bone transplantation

....

..05). Autogenous bone generally resulted in a more favorable outcome over a 3-year period. Smoking adversely impacted implant survival in sinus grafts...

..Scaffolds processed by using a methodology based on extrusion with blowing agents...

....

..The technique of impaction grafting appears to be reliable, can be learned rapidly and produces a predictably low incidence of aseptic loosening...

..The purpose was to qualitatively and quantitatively compare the bone formation and graft resorption of two different bone substitutes used in both orthopedic and oral surgery, with autogenous bone as a positive control...

..Much more research and development are necessary to find a suitable carrier for rhBMP-2, and to study the properties of newly formed bone that it has induced before it can be a substitute for autogenous bone...

..4+/-3.7% initially to 1.7+/-1.2% at 12 weeks). This study shows that synthetic bone substitutes may have superior stability and osteogenic properties than autologous bone grafts in critical-sized bone defects...

..5% to 63.5%) and 82% (95% CI 72.4% to 91.6%), respectively. The mid-term results of revision total hip replacement with the Kerboull device were better when bulk graft was used in any size of bone defect...

..We present our current approach to the use of the RIA system, including the preoperative planning, the details of the operative procedure, the pitfalls and the potential complications that could be encountered...

..The induced membrane appears as a biological chamber, which allows the conception of numerous experimental models of bone reconstruction. This concept could probably be extended to other tissue repair...

..BMAC combined with HA can reduce the time needed for healing of bone defects when compared to BMAC in combination with collagen sponge...

..Femoral impaction grafting requires vigorous impaction to obtain adequate stability without risk of fracture, but the force of impaction has not been determined. We determined this threshold force in a preliminary study using animal femurs...

..Although the problems associated with the use of OP-1 in impaction grafting may be solved by adding a bisphosphonate, some of the benefits of OP-1 can be lost...

..This combination might be useful in various conditions in orthopedic reconstruction...

..Level of Evidence: Therapeutic study, Level IV (case series--no, or historical control group). See the Guidelines for Authors for a complete description of levels of evidence...

..Single-level cervical radiculopathy was treated with four different techniques. The clinical outcome and cost-effectiveness were compared in this study...

..The article also examines some of the research being done in "tissue engineering" to get a sense of the future of bone grafting...

..The vascularized fibula can be used to maintain growth by virtue of transferring the physis. The vascularized fibula is thus both the workhorse and thoroughbred in long bone construction...

..However, increased soft tissue damage and high complication rate has led to search less invasive surgical methods such as minimal invasive plating technique...

..The future will show if further sockets loosen and if the loose sockets up to date will end up in rerevisions...

..1% of the grafted region after 9 months at the time when the canine and lateral incisor in the affected side erupted in the reconstructed alveolar ridge...

..Bisphosphonates are used to reduce resorption of necrotic bone. We tested a systemic pretreatment before harvesting the graft in order to protect the bone and cartilage against collapse and secondary arthrosis...

..Harvesting bone from the iliac crest for alveolar bone grafting is well tolerated by patients, has few important complications, and gives an aesthetically acceptable scar at the donor site...

..In addition, we report our preliminary results with trabecular metal cups and trabecular metal cup-cage constructs used in conjunction with bone graft for addressing major bone defects...

....

..001). Washing had no effect on cohesion. The addition of clotted blood significantly increased the cohesion of both pure bone (p < 0.019) and mixes with pure bone and with porous graft extender (p < 0.044)...

..Procedures whereby an existing acetabulum defect was filled with bone chips that were impacted into a strong layer, after which a cemented total hip prosthesis was implanted...

..The purpose of this study is to evaluate the bony regeneration of premaxillary clefts in humans using recombinant human bone morphogenetic protein type 2 in a collagen sponge carrier...

..In the current study we examined whether this reduction represented a final loss of ingrowth or was just a delay, and whether the reduction can be overcome and ultimately results in a better late ingrowth...

..We conclude that the size of grafted particles of bone and the spaces between particles are important determinants of osteogenesis during guided bone regeneration...

....

..Long-term survival of uncemented total joint replacements relies on osseointegration. With reduced bone stock impacted morselized allograft enhances early implant fixation but is subject to resorption...

..The fibula is a source of bone graft for reconstruction of the appendicular and axial skeleton...

..The findings suggest that procedural refinements of limiting subcutaneous dissection and providing layered tension-free incision closure may improve results...

..The data suggest that a cage filled with a loaded morselized graft could be an alternative for the massive cortical graft in reconstruction of large diaphyseal defects in an animal model...

..This study was undertaken to evaluate the effect of hyperbaric oxygen (HBO) on the repair of critical-sized defects in the presence and absence of a nonvascularized autogenous bone graft...

..Level of Evidence: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence...

..LEVEL OF EVIDENCE: Level II, prognostic study...

..Strontium delivered as doping of an HA bone graft extender showed potential as a dual acting agent in the interface. However, delivery methods of strontium to the bone-implant interface clearly need further investigation...

..A new procedure using a resorbable collagen matrix with bone morphogenetic protein (BMP)-2 was compared with traditional iliac crest bone graft to close alveolar defects in older patients...

..The limited contact between implant and host bone does not seem to compromise implant survival in the 7- to 11-year perspective...

..Clefts of the lip and palate are the most prevalent congenital craniofacial birth defect in humans. The developing field of tissue engineering is considered for the management of clefts of the lip and palate...

..Our findings support the conclusion that the outcome of early SABG is superior to late SABG. The overall success rate of SABG sample (74%) compared relatively well with other published results...

..In clinical practice, vascularized bioartificial bone grafts could change the principles of bone transplantation with minimal donor site morbidity and no shape or volume limitations.

..The removal of these antigenic proteins from the allografts prior to surgery may alleviate this immunological reactivity and improve graft outcome...

..In this study, we examined the rates of perioperative complications associated with posterior lumbar decompression and arthrodesis in patients sixty-five years of age or older...

..Complete osseous remodeling may not be necessary to obtain a good clinical result with a morselized impacted graft...

..Grafted material was also identified using follow-up radiographs. In the presented cases, PBBM showed clinically satisfactory results as a biocompatible filler in bone augmentation procedures...

..Local graft treatment with a bisphosphonate before insertion seems to be risk-free, and may prevent mechanical graft failure due to resorption in patients...

..CONCLUSION: Although more extensive testing is needed to explain the clinical implications of these results, the findings of this study may help clinicians choose the most appropriate donor bone...

..In patients who fail to heal a scaphoid fracture, several factors may contribute, including delay in treatment, fracture displacement, proximal third location, avascular necrosis, and associated carpal instability...

..The results were compared with a group of 3 patients treated with sinus floor elevation and autogenous bone grafts...

..In cases where more resources are available, the addition of adjuvant therapies, as noted in the recent literature, may be beneficial. The results of this study should be considered when designing multicenteric studies in the future...

..The purpose of this investigation was to assess the functional outcome and complication rate following treatment with a bone allograft to reconstruct the pelvis...

..Conventional treatment for tibiotalar joint arthritis relies on arthrodesis or prosthetic arthroplasty. Fresh osteochondral allografting is an alternative procedure to replace diseased articular cartilage...

..This was usually apparent by 6 months postoperatively. We conclude that the addition of autologous marrow to irradiated bone allograft during impaction grafting is a cheap and highly effective way of achieving graft incorporation...

..Antibiotic loaded allograft bone is a powerful tool in septic revision surgery, enabling restoration of bone stock, insertion of a new implant and control of infection in a single operation...

..Giant cell tumors of bone rarely metastasize but often recur locally after surgery. There is limited knowledge about the risk of recurrence related to different types of treatment...

..The purpose of this study was to evaluate the clinical and radiographic outcomes of revision of the femoral component of a hip arthroplasty with use of an impaction bone-grafting technique and a cemented polished stem...

The terminology of bone transplantation is complicated by the various histologic types of bone grafts...

..Although our results remain inconsistent, tibial allograft reconstruction in selected patients may restore complete and durable function of the limb...

..Level of Evidence: Level III, prognostic study. See Guidelines for Authors for a complete description of levels of evidence...

..The purpose of this study was to evaluate and compare postoperative anterior knee pain, knee stability, and functional scores of an autogenous bone-patellar tendon-bone (BPTB) graft and a quadriceps tendon-bone (QTB) graft...

..Rough surfaces and delayed implant placement seem to increase implant success in these areas...

....

..In both patients, the osseous reconstruction of the residual ridge allowed the placement of implants for a fixed bridge reconstruction...

..To present a simple and objective method for the planning of maxillary implant reconstruction with autogenous bone graft in maxilla atrophy...

..This study was designed to clinically and histologically evaluate the integration of titanium implants in different grafting materials used for maxillary sinus augmentation procedures...

..Histologically, both MCBA and ABBM particles were surrounded by new bone, osteoid, and osteoblasts. A higher average percentage of new vital bone was seen around the MCBA particles than around the ABBM particles...

..The purpose of this clinical follow-up study was to report the clinical outcome of osseointegrated implants placed in extremely atrophied edentulous maxillae after Le Fort I osteotomy and interpositional autogenous iliac bone grafts...

..Sparse particles of grafted bone were evident in direct contact with the regenerated bone. Marrow spaces showed a normal stromal component with limited grafted particles...

..This article discusses this information and answers further questions relating to the sinus elevation procedure...

..Surgical access to the zygoma is simple and can be performed using local anesthesia. Postoperative complications after zygomatic bone harvest are minimal...

..The clinical report demonstrated the potential of the titanium mesh to achieve extensive alveolar ridge augmentation, whereas the augmented ridge may possess an inferior capability forbone remodeling...

..Significant differences were found for mean percentage reduction of the defect height and area only between the two implant subgroups within each group...

..To evaluate healing of marginal defects in immediate transmucosal implants grafted with anorganic bovine bone, and to assess mucosal and radiographic outcomes 3-4 years following restoration...

....

..Localized internal sinus elevation may represent a more conservative approach to treat the deficient posterior maxilla, but at present the histologic and clinical comparisons to the traditional lateral sinus elevation are lacking...

..A prospective, randomized clinical study comparing beta-tricalcium phosphate (beta-TCP) with autograft bone graft with follow-up of 3 years...

..In cases when the alveolar crest is too narrow to host an implant, lateral augmentation is required. The use of autogenous bone blocks harvested from the iliac crest is often demanded. One disadvantage is the associated patient morbidity...

..2 months). The success rate was 97.4% according to Albrektsson's criteria. These preliminary data indicate that the simplified osteotome technique is effective and safe, though long-term, multicenter studies are still needed...

..The mean functioning time was 12 months, varying from 9 to 24 months. CONCLUSION: The results indicate that DFBP resorbs earlier than PHA and DBBG in sinus lift procedures...

..Histologic analysis revealed bone regeneration. Although this approach needs further investigation, this report emphasizes the potential for the use of rhPDGF for simultaneous soft and hard tissue implant site preparation...

..Objectives: The aim of the following investigation was to quantify the resorption rate of tissue-engineered bone grafts in the maxillary sinus using volume measurements...

..The aim of this study was to determine the clinical and histologic results of a porous synthetic hydroxyapatite (HA) compared with bovine-derived HA used in maxillary sinus augmentation...

..The purpose of the present review is to provide a critical overview of the current applications of DBM in a clinical setting...

..5 years of functional loading. No fixture loss occurred in non-augmented areas...

..The aim of this study was to determine the effectiveness of this technique in delayed and immediate implant cases in which specific augmentation materials differed...

..Following an adequate healing period, the patient's treatment was completed by an implant-supported restoration. The case is used to illustrate surgical options available in the restoration of the anterior partially edentulous maxilla...

..The aim of this study was to compare, through histomorphometric analysis, the use of donor autogenous bone graft from calvarial or iliac sources for maxillary sinus lift procedures...

..To analyze publications related to augmentation procedures and to evaluate the success of different surgical techniques for ridge reconstruction and the survival/success rates of implants placed in the augmented areas...

....

..The aim of this study was to evaluate the capability of a configured titanium mesh (CTM) to serve as a mechanical and biologic device for restoring a vertically defected/resorbed alveolar ridge...

..A prospective, randomized, controlled, multicenter clinical study was conducted...

..There were no adverse events related to the OP-1 putty implant in this study, which supports findings in other studies suggesting the safety of bone morphogenetic proteins in spinal surgery...

..Future research is needed to determine the clinical significance and the cost- and risk-benefit considerations of the approach...

..Part of this study was presented at the 15th ICOMS, Durban, South Africa, 19-24 May 2001...

..The sinus graft showed intense bone formation 6 months after grafting and a further increase in bone growth 10 months after grafting...

..We present a new internal crestal approach that addresses these issues...

....

..This grant will provide a head to head comparison of the osteoprogenitor potential for bone transplantation of cells from 5 different tissues...

..This grant will provide a head to head comparison of the osteoprogenitor potential for bone transplantation of cells from 5 different tissues...

..This could be especially valuable in assessing retinal function of patients with heterogeneous damage as in retinitis pigmentosa, diabetic retinopathy, and glaucoma. ..

..monkeys in which INL activity is pharmacologically dissected, b. normal human subjects, c. patients with disease of the INL, and d. mathematical work. ..

..These same techniques can enable the ophthalmologist to monitor the health of these cells and, thus the effectiveness of alternative treatments. ..

..Finally, patients with acute optic neuritis will be followed with behavioral and mVEP techniques. An attempt will be made to understand the recovery o vision following optic neuritis (ON). ..

..The experiments under Aim 4 are designed to improve on the currently available methods of recording and analyzing the multifocal VEP. The aim is to improve the efficacy of the multifocal VEP technique in the clinic. ..

..The experiments under Aim 4 are designed to improve on the currently available methods of recording and analyzing the multifocal VEP. The aim is to improve the efficacy of the multifocal VEP technique in the clinic. ..

..We propose as part of aim 3 to improve our understanding of these relationships as well as to improve our analysis of visual field data. ..

..Finally, we intend to obtain a better understanding of the relative involvement of the rod and different cone mechanisms in retinitis pigmentosa and in progressive cone dystrophy...

..The data will be analyzed within the context of recent models of cone systems, models based on recent physiology...

..Thus, we propose to develop a model of the human ERG that encompasses the activity of the inner nuclear layer as well as the receptors...

..abstract_text> ..

..Standardized hard and soft tissue data will be collected preextraction as baseline, and then prospectively for at least two years in this trial, to compare and contrast the methods. ..

..It is suggested that these results will provide insight into the role these factors play in bone development and repair. ..

..The technology that will be developed in performing the proposed work will have broad impact on the field of stem cell biology, the application of tissue engineering, and on the treatment of children with craniosynostosis. ..

..abstract_text> ..

..These procedures can be designed to specifically irradicatge all of MTSCs and thus improve patient survival rate and functional outcome of tumor therapy. ..

..Both organizations, IRG and WCOI-6 have approved the collaborations. Experience has been that 400 or more implant dentists attend the WCOI-6 and i00 or more researchers attend the IRG satellite sessions. ..

..The technology that will be developed in performing the proposed work will have broad impact on the field of stem cell biology, the application of tissue engineering, and on the treatment of children with craniosynostosis. ..