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| insufflationSummarySummary: The act of blowing a powder, vapor, or gas into any body cavity for experimental, diagnostic, or therapeutic purposes. Top Publications
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Publications
Feasibility and surgical approach of transaxillary robotic thyroidectomy without CO(2) insufflationCarol M Lewis
Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
Head Neck 32:121-6. 2010..Our objective was to evaluate the anatomic basis for robotic-assisted transaxillary thyroidectomy and to determine its feasibility in a prospective clinical trial...
NORCCAP (Norwegian colorectal cancer prevention): a randomised trial to assess the safety and efficacy of carbon dioxide versus air insufflation in colonoscopyM Bretthauer
NORCCAP Centre, Telemark Central Hospital, Porsgrunn, Norway Department of Anaesthesiology, Telemark Central Hospital, Porsgrunn, Norway
Gut 50:604-7. 2002..the risk of combustion during electrosurgical procedures and to reduce patient discomfort, carbon dioxide (CO2) insufflation has been recommended during colonoscopy...
Randomized, controlled trial of carbon dioxide insufflation during colonoscopyJ Church
Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Dis Colon Rectum 46:322-6. 2003INTRODUCTION: Insufflation of air is a cause of discomfort during and after colonoscopy. Although this can be minimized by good technique, the use of carbon dioxide insufflation may provide further benefits...
A pilot study to assess the safety and efficacy of carbon dioxide insufflation during colorectal endoscopic submucosal dissection with the patient under conscious sedationYutaka Saito
Division of Endoscopy, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
Gastrointest Endosc 65:537-42. 2007..This procedure is performed by using air insufflation, is time consuming, and is associated with severe abdominal discomfort...
Minimizing postcolonoscopy abdominal pain by using CO(2) insufflation: a prospective, randomized, double blind, controlled trial evaluating a new commercially available CO(2) delivery systemKatica Sumanac
McMaster University Medical Center, Hamilton, Ontario, Canada
Gastrointest Endosc 56:190-4. 2002..The effects of CO(2) and air insufflation on residual bowel gas and postprocedure pain were compared...
Effects of pneumoperitoneum created through CO2 insufflation and parameters of mechanical ventilation (PEEP application) on systemic dissemination of intraabdominal infectionsU Barbaros
Department of General Surgery, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey
Surg Endosc 18:501-7. 2004..To examine whether CO2 pneumoperitoneum and positive end expiratory pressure (PEEP) in mechanical ventilation affect the systemic spread of intraabdominal infection...
The use of carbon dioxide for insufflation during GI endoscopy: a systematic reviewEvan S Dellon
Department of Medicine, Division of Gastroenterology and Hepatology, Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7080, USA
Gastrointest Endosc 69:843-9. 2009b>Insufflation of the lumen is required for visualization during GI endoscopy. Carbon dioxide (CO(2)) has been proposed as an alternative to room air for insufflation.
Heating of carbon dioxide during insufflation alters the peritoneal fibrinolytic response to laparoscopic surgery : A clinical trialW J A Brokelman
Department of Surgery, Alysis Zorggroep, locatie Rijnstate, Wagnerlaan 55, 6815, AD, Arnhem, The Netherlands
Surg Endosc 22:1232-6. 2008..It involves the creation of a pneumoperitoneum, mostly using carbon dioxide. Cooling of the peritoneum, due to insufflation, might traumatize the peritoneum and disturb peritoneal fibrinolysis, important in peritoneal healing processes...
Is carbon dioxide insufflation safe for laparoscopic surgery? A model to assess the effects of carbon dioxide on transitional-cell carcinoma growth, apoptosis, and necrosisBeng Jit Tan
Department of Urology, Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA
J Endourol 20:965-9. 2006To study the effects of carbon dioxide insufflation pressure and concentration on the adhesion, growth, apoptosis, and necrosis of transitional-cell carcinoma (TCC).
Hemodynamics and gas exchange during carbon dioxide insufflation for totally endoscopic coronary artery bypass graftingC Byhahn
Department of Anesthesiology, JW Goethe University Hospital, Frankfurt, Germany
Ann Thorac Surg 71:1496-501; discussion 1501-2. 2001In addition to single-lung ventilation (SLV), positive-pressure CO2 insufflation is mandatory for totally endoscopic coronary artery bypass grafting...
Safety of carbon dioxide insufflation for upper gastrointestinal tract endoscopic treatment of patients under deep sedationSatoru Nonaka
Endoscopy Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
Surg Endosc 24:1638-45. 2010..This study aimed to investigate the safety of CO(2) insufflation used for esophageal and gastric endoscopic submucosal dissection (ESD) in patients under deep sedation.
Abdominal insufflation decreases blood loss without worsening the inflammatory response: implications for prehospital control of internal bleedingGeorge C Velmahos
Division of Trauma, Emergency Surgery, and Surgical Critical Care, The Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
Am Surg 74:297-301. 2008Abdominal insufflation (AI) by carbon dioxide has been shown to decrease the rate of bleeding in different swine models of abdominal organ injuries...
Carbon dioxide insufflation in colonoscopy: safe and effective in sedated patientsM Bretthauer
Dept of Gastroenterology, Rikshospitalet University Hospital, Oslo, Norway
Endoscopy 37:706-9. 2005Several studies have shown that insufflation of carbon dioxide (CO2) instead of air during colonoscopy can reduce postprocedural pain. However, CO2 insufflation might also lead to CO2 retention in the human body...
Carbon dioxide insufflation for more comfortable endoscopic retrograde cholangiopancreatography: a randomized, controlled, double-blind trialM Bretthauer
Department of Medicine, Section of Gastroenterology, Rikshospitalet University Hospital, Oslo, Norway
Endoscopy 39:58-64. 2007The effect on abdominal pain of using carbon dioxide (CO2) for insufflation during endoscopic retrograde cholangiopancreatography (ERCP) has not been investigated...
Carbon dioxide insufflation improves intubation depth in double-balloon enteroscopy: a randomized, controlled, double-blind trialD Domagk
Department of Medicine B, University Hospital of Munster, Munster, Germany
Endoscopy 39:1064-7. 2007..However, intubation depth is limited by distention of the small bowel due to air insufflation during the procedure...
Transcutaneous monitoring of partial pressure of carbon dioxide during endoscopic submucosal dissection of early colorectal neoplasia with carbon dioxide insufflation: a prospective studyTsuyoshi Kikuchi
Endoscopy Division, National Cancer Center Hospital, Chuo Ku, Tokyo, 104 0045, Japan
Surg Endosc 24:2231-5. 2010The authors have reported that carbon dioxide (CO(2)) insufflation is safe and effective for lengthy endoscopic submucosal dissection (ESD) with the patient under conscious sedation...
Lung insufflation capacity in neuromuscular diseaseJohn Robert Bach
Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey, USA
Am J Phys Med Rehabil 87:720-5. 2008To compare maximal passive lung insufflation capacity (LIC) with lung inflation by air stacking (to maximum insufflation capacity [MIC]) and with vital capacity (VC); to explore relationships between these variables that correlate with ..
The cardiopulmonary effects of single-lung ventilation and carbon dioxide insufflation during thoracoscopic internal mammary artery harvestingThomas A Vassiliades
Pensacola Heart Institute, Pensacola, Florida, USA
Heart Surg Forum 5:22-4. 2002..The technique involves the use of single-lung ventilation and carbon dioxide insufflation to maximize exposure and facilitate rapid dissection...
Carbon dioxide insufflation for colonoscopy: evaluation of gas volume, abdominal pain, examination time and transcutaneous partial CO2 pressureHiro o Yamano
Department of Gastroenterology, Akita Red Cross Hospital, 222 1 Kami kitade saruta, Akita, Akita, 010 1495, Japan
J Gastroenterol 45:1235-40. 2010b>Insufflation with carbon dioxide (CO(2)) in colonoscopy has not been widely adopted and, consequently, limited data are available on insufflated gas volume and blood pCO(2)...
Retroperitoneoscopic living donor nephrectomy without gas insufflation: the five-year Hamamatsu University experienceKazuo Suzuki
Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Japan
Transplant Proc 34:720-1. 2002
Hemodynamic responses to intrapleural insufflation with hemipulmonary collapseT Ohtsuka
Department of Cardiothoracic Surgery, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
Surg Endosc 15:1327-30. 2001The hemodynamic effects of carbon dioxide (CO2) insufflation with hemipulmonary collapse were studied in consecutive thoracoscopic harvests of the left or right internal mammary artery (IMA), which were used for video-assisted coronary ..
Intraoperative evaluation of laparoscopic insufflation technique for quality control in the ORV R Jacobs
Department of Surgery, Fayette Medical Center, AL 35555, USA
JSLS 4:189-95. 2000..For intraoperative evaluation of insufflation techniques, a data acquisition model for quality control study of potential insufflation problems is necessary.
Perforated colon secondary to virtual colonoscopy: report of a caseLoretta Coady-Fariborzian
Division of Colon and Rectal Surgery, Department of Surgery, North Shore University Hospital, Manhasset, New York, USA
Dis Colon Rectum 47:1247-9. 2004..The pathologic findings were described as ulcerative colitis with full-thickness perforation. To the best of our knowledge, this is the first complication from a virtual colonoscopy reported in the literature...
Endoscopic thyroid resection using cutaneous elevation in lieu of insufflationH Kitano
Department of Otolaryngology, Head and Neck Surgery, Shiga University of Medical Science, Seta, Otsu, Shiga 520 2192, Japan
Surg Endosc 16:88-91. 2002..Laparoscopic surgery to resect cervical masses has gained increasing acceptance during the past decade. This report describes the authors' technique and experience using total video endoscopic surgery to resect thyroid masses...
Colonic perforation at CT colonography in a patient without known colonic diseaseBrett M Young
Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
AJR Am J Roentgenol 186:119-21. 2006
Automated insufflation of carbon dioxide for MDCT colonography: distension and patient experience compared with manual insufflationDavid Burling
Department of Intestinal Imaging, St. Mark's and Northwick Park Hospitals, Harrow HA1 3UJ, UJK
AJR Am J Roentgenol 186:96-103. 2006OBJECTIVE: The purpose of our study was to compare the effects of automated and manual carbon dioxide insufflation before CT colonography on distention and patient acceptance...
Endoscopic cross-trigonal ureteral reimplantation under carbon dioxide bladder insufflation: a novel techniqueC K Yeung
Division of Paediatric Surgery, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China
J Endourol 19:295-9. 2005..of endoscopic intravesical ureteral mobilization and cross-trigonal ureteral reimplantation under carbon dioxide insufflation of the bladder (pneumovesicum) for correcting primary vesicoureteral reflux (VUR) in infants and children.
Mechanical properties of the human abdominal wall measured in vivo during insufflation for laparoscopic surgeryC Song
Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, Scotland
Surg Endosc 20:987-90. 2006BACKGROUND: Carbon dioxide insufflation of the peritoneal cavity for laparoscopic surgery offers a unique opportunity to measure some mechanical properties of the human abdominal wall that hitherto have been difficult to obtain...
Minimizing diaphragmatic injury during radiofrequency ablation: efficacy of intraabdominal carbon dioxide insufflationSteven S Raman
Department of Radiology, David Geffen School of Medicine at UCLA, BL 428 CHS Box 951721, Los Angeles, CA 90095 1721, USA
AJR Am J Roentgenol 183:197-200. 2004The purpose of our study was to determine whether intraperitoneal insufflation of carbon dioxide (CO(2)) reduces adjacent diaphragmatic injury.
Bedside transpyloric tube placement in the pediatric intensive care unit: a modified insufflation air techniquePaulo Sergio Lucas da Silva
Rua das Aroeiras, 30 ap 22 Bairro Jardim, Santo Andre, Sao Paulo, 09090 000, Brazil
Intensive Care Med 28:943-6. 2002To test air insufflation as an adjunct to placement of enteral feeding tubes and the effectiveness of using a smaller insufflation volume in pediatric patients.
Acetazolamide reduces referred postoperative pain after laparoscopic surgery with carbon dioxide insufflationHarvey J Woehlck
Department of Anethesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
Anesthesiology 99:924-8. 2003..Acidification of the peritoneum by carbonic acid may be the major cause of pain from carbon dioxide insufflation. Carbonic anhydrase is an enzyme that increases the rate of carbonic acid formation from carbon dioxide...
Actual colonic perforation in virtual colonoscopy: report of a caseMoshe Kamar
Department of Surgery and Transplantation, Sheba Medical Center, Tel-Hashomer, Israel
Dis Colon Rectum 47:1242-4; discussion 1244-6. 2004..Thus, it is suggested that in such cases, air insufflation should be gradual, thereby minimizing the risk of perforation.
Cardiopulmonary, blood and peritoneal fluid alterations associated with abdominal insufflation of carbon dioxide in standing horsesF G Latimer
Equine Health Studies Program, Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, USA
Equine Vet J 35:283-90. 2003REASONS FOR PERFORMING STUDY: Abdominal insufflation is performed routinely during laparoscopy in horses to improve visualisation and facilitate instrument and visceral manipulations during surgery...
Effects of expiratory tracheal gas insufflation in patients with severe head trauma and acute lung injuryMelcior Martínez-Pérez
Critical Care Center, Hospital de Sabadell, Corporacio Parc Tauli, Institut Universitari Fundació Parc Taulí, Universitat Autonoma de Barcelona corrected 08206 Sabadell, Spain
Intensive Care Med 30:2021-7. 2004This study analyzed the effect of phasic tracheal gas insufflation at mid- to end-expiration in patients with severe head trauma and acute lung injury (ALI)/acute respiratory distress syndrome (ARDS).
Double-blind, prospective, randomized study of warmed, humidified carbon dioxide insufflation vs standard carbon dioxide for patients undergoing laparoscopic cholecystectomyDavid R Farley
Departments of Surgery and Biostatistics, Mayo Clinic, Rochester, Minn. 55905, USA
Arch Surg 139:739-43; discussion 743-4. 2004HYPOTHESIS: Patients undergoing warmed, humidified carbon dioxide (CO2) insufflation for laparoscopic cholecystectomy will (1) maintain a warmer intraoperative core temperature, (2) have their surgeon experience less fogging of the camera ..
Heated and humidified insufflation during laparoscopic gastric bypass surgery: effect on temperature, postoperative pain, and recovery outcomesMohamed A Hamza
Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center at Dallas, 5161 Harry Hines Boulevard, CS 2.282, Dallas, TX 75390, USA
J Laparoendosc Adv Surg Tech A 15:6-12. 2005..We performed a sham-controlled study to test the hypothesis that active warming and humidification of the insufflation gas reduces intraoperative heat loss and improves recovery outcomes...
Supplementation of pre-oxygenation in morbidly obese patients using nasopharyngeal oxygen insufflationA S Baraka
Department of Anaesthesiology, American University of Beirut, Beirut, Lebanon
Anaesthesia 62:769-73. 2007..This study compares pre-oxygenation alone with pre-oxygenation followed by nasopharyngeal oxygen insufflation on the onset of desaturation occurring during the subsequent apnoea...
Primary microparticles and agglomerates of morphine for nasal insufflationPaola Russo
Department of Pharmacy, University of Parma, Parco Area delle Scienze 27/A, 43100 Parma, Italy
J Pharm Sci 95:2553-61. 2006..The agglomerates of morphine crystals mixed with mannitol/lecithin microparticles showed superior stability. However, the drug permeation through rabbit mucosa was slower than with spray-dried morphine microparticle agglomerates...
Prospective randomized trial of heated humidified versus cold dry carbon dioxide insufflation during laparoscopic gastric bypassJ K Champion
Department of Surgery, Emory Dunwoody Medical Center, Atlanta, GA 30060, USA
Surg Obes Relat Dis 2:445-9; discussion 449-50. 2006The replacement of cold dry carbon dioxide with heated humidified gas for insufflation during complex laparoscopic procedures has been reported to decrease hypothermia and peritoneal cell desiccation, with a resultant decrease in ..
Effect of manually assisted cough and mechanical insufflation on cough flow of normal subjects, patients with chronic obstructive pulmonary disease (COPD), and patients with respiratory muscle weaknessP Sivasothy
Respiratory Support and Sleep Centre, Papworth Hospital, Papworth Everard, Cambridge CB3 8RE, UK
Thorax 56:438-44. 2001It has been suggested that cough effectiveness can be improved by assisted techniques. The effects of manually assisted cough and mechanical insufflation on cough flow physiology are reported in this study.
Comparison between intraperitoneal CO2 insufflation and abdominal wall lift on QT dispersion and rate-corrected QT dispersion during laparoscopic cholecystectomyH Egawa
Department of Anesthesiology, Dokkyo University School of Medicine, Mibu, Tochigi 321-0293, Japan
Surg Laparosc Endosc Percutan Tech 16:78-81. 2006This study compared the effect of intraperitoneal CO2 insufflation with abdominal wall lift on RR interval, QT interval, the rate-corrected QT (QTc) interval, QT dispersion (QTD), and the rate-corrected QTD (QTcD) using computerized ..
CO2 environment influences the growth of cultured human cancer cells dependent on insufflation pressureC N Gutt
Department of General and Vascular Surgery, Johann Wolfgang Goethe University, Theodor Ster Kai 7, Frankfurt Main, Germany
Surg Endosc 15:314-8. 2001..Previous experiments performed both in vitro and in vivo have proved that CO2 insufflation stimulates malignant cell growth...
Initial trocar placement and abdominal insufflation in laparoscopic bariatric surgeryAtul K Madan
Minimally Invasive Surgery Section, Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Surg Res 148:210-3. 2008Initial trocar placement and abdominal insufflation in laparoscopic bariatric surgery can be challenging for the novice. One technique is the use of an optical viewing trocar without prior abdominal insufflation...
Application of tracheal gas insufflation to acute unilateral lung injury in an experimental modelL Blanch
Department of Pulmonary and Critical Care Medicine, University of Minnesota, Regions Hospital, St Paul, Minnesota, USA
Am J Respir Crit Care Med 164:642-7. 2001..We hypothesized that selective application of tracheal gas insufflation (TGI) will recruit the injured lung without causing overdistension of the normal lung...
Patient-controlled room air insufflation versus automated carbon dioxide delivery for CT colonographyTheodore J Shinners
Department of Radiology, University of Wisconsin Medical School, Clinical Science Center, 600 Highland Ave, Madison, WI 53792, USA
AJR Am J Roentgenol 186:1491-6. 2006..colonic distention and patient comfort at screening CT colonography (CTC) with patient-controlled room air (RA) insufflation versus automated carbon dioxide (CO2) delivery...
Effects of carbon dioxide insufflation for laparoscopic cholecystectomy on the respiratory systemP Pelosi
Department of Anaesthesia and Intensive Care, University of Milan, Ospedale Maggiore IRCCS, Italy
Anaesthesia 51:744-9. 1996..in total respiratory system, lung and chest wall mechanics, lung volume and gas-exchange during abdominal insufflation with carbon dioxide for laparoscopic cholecystectomy were studied...
CO2 abdominal insufflation pretreatment increases survival after a lipopolysaccharide-contaminated laparotomyJoseph M Fuentes
Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Gastrointest Surg 10:32-8. 2006..The presented studies were designed to determine whether treating animals with CO(2) abdominal insufflation before undergoing a lipopolysaccharide (LPS)-contaminated laparotomy would serve as "shock prophylaxis&..
New tools in ventilatory support: high frequency ventilation, nitric oxide, tracheal gas insufflation, non-invasive ventilationD Biarent
Pediatric and Neonatal Intensive Care Unit, Hopital Universitaire des Enfants, Reine Fabiola, Brussels, Belgium
Pediatr Pulmonol Suppl 18:178-81. 1999..Tracheal gas insufflation, in addition to conventional ventilation, by washing dead space during exhalation, improves gas exchange while ..
Nasopharyngeal oxygen insufflation following pre-oxygenation using the four deep breath techniqueS K Taha
Department of Anaesthesiology, American University of Beirut, Beirut, Lebanon
Anaesthesia 61:427-30. 2006This paper evaluates the effectiveness of nasopharyngeal oxygen insufflation following preoxygenation using the four deep breath technique within 30 s, on the onset of haemoglobin desaturation during the subsequent apnoea...
Advice for optimizing colonic distention and minimizing risk of perforation during CT colonographyAbraham H Dachman
Department of Radiology, MC 2026, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
Radiology 239:317-21. 2006
Minimally invasive neck surgery. Surgical feasibility and physiological effects of carbon dioxide insufflation in a unilateral subplatysmal approachP A Kessler
Department of Cranio Maxillofacial Surgery, Maastricht UMC, Postbus 5800, NL 6202 Maastricht, The Netherlands
Int J Oral Maxillofac Surg 38:766-72. 2009Endoscopically assisted, minimally invasive techniques to regions without a natural cavity require insufflation with carbon dioxide (CO2)...
Tracheal gas insufflation as an adjunct to mechanical ventilationAvi Nahum
Pulmonary and Critical Care Department, Regions Hospital, 640 Jackson Street, St Paul, MN 55101 2595, USA
Respir Care Clin N Am 8:171-85, v-vi. 2002Tracheal gas insufflation (TGI) as an adjunct to mechanical ventilation delivers fresh gas into the central airways continuously or in a phasic fashion to improve the efficiency of alveolar ventilation or to minimize the ventilatory ..
Animal and lung model studies of tracheal gas insufflationA Nahum
Regions Hospital, Pulmonary and Critical Care Department, 640 Jackson Street, St Paul MN 55101 2595, USA
Respir Care 46:149-57. 2001Tracheal gas insufflation (TGI) is the continuous or phasic insufflation of fresh gas into the central airways for the purpose of improving the efficiency of alveolar ventilation and/or minimizing the ventilatory pressure requirements...
Twenty-five simple ways to increase insufflation performance and patient safety in laparoscopyVolker R Jacobs
Frauenklinik (OB/GYN, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
J Am Assoc Gynecol Laparosc 11:410-23. 2004Technical aspects of laparoscopic insufflation technique and interaction among patient, technique, and physician can affect the performance of laparoscopy and patient safety...
Comparison of high-frequency oscillation and tracheal gas insufflation versus standard high-frequency oscillation at two levels of tracheal pressureSpyros D Mentzelopoulos
First Department of Intensive Care Medicine, University of Athens Medical School, Athens, Greece
Intensive Care Med 36:810-6. 2010In acute respiratory distress syndrome (ARDS), combined high-frequency oscillation (HFO) and tracheal gas insufflation (TGI) may improve oxygenation through a TGI-induced increase in mean tracheal pressure (P(tr))...
A novel laparoscopic technique for removal of foreign bodies from the urinary bladder using carbon dioxide insufflationBala S Reddy
Department of Paediatric Surgery, Hull Royal Infirmary, Kingston upon Hull, United Kingdom
Surg Laparosc Endosc Percutan Tech 14:238-9. 2004....
Cough augmentation with mechanical insufflation/exsufflation in patients with neuromuscular weaknessM Chatwin
Sleep and Ventilation Unit, Royal Brompton Hospital, London, UK
Eur Respir J 21:502-8. 2003..Mechanical insufflation/exsufflation may improve cough efficacy by increasing peak cough flow...
Meta-analysis of the effect of warm humidified insufflation on pain after laparoscopyT Sammour
Department of Surgery, South Auckland Clinical School, University of Auckland, New Zealand
Br J Surg 95:950-6. 2008Studies on the use of warmed and humidified insufflation (WHI) in laparoscopic abdominal procedures to reduce pain have been inconclusive owing to small sample sizes.
Intra-airway gas transport during high-frequency chest vibration with tracheal insufflation in dogsN Gavriely
Department of Anesthesia, Northwestern University Medical School, Chicago 60611, USA
J Appl Physiol 79:243-50. 1995High-frequency external chest vibration with tracheal insufflation (high-frequency vibration ventilation) has previously been shown to be an effective mode of artificial ventilation in experimental animals...
Arterial PCO2 and cardiovascular function during endoscopic neck surgery with carbon dioxide insufflationR Bellantone
Division of Endopcrine Surgery, Catholic University, Rome, Italy
Arch Surg 136:822-7. 2001..Concerns about the use of carbon dioxide insufflation in the neck exist owing to reports of potential adverse metabolic and hemodynamic changes...
Cardiac function during intraperitoneal CO2 insufflation for aortic surgery: a transesophageal echocardiographic studyPascal Alfonsi
Department of Anesthesiology, and Intensive Care Unit, Ambroise Pare University Hospital, Assistance Publique Hopitaux de Paris, Boulogne, Cedex, France
Anesth Analg 102:1304-10. 2006..In conclusion, peritoneal CO2 insufflation in patients scheduled for laparoscopic aortic surgery could impair LV and RV systolic functions as a ..
Reduction of abdominal wall blood flow by clamping or carbon dioxide insufflation increases tumor growth in the abdominal wall: an experimental study in ratsO Lundberg
Department of Surgical and Perioperative Sciences, Umea University Hospital, SE 901 85, Umea, Sweden
Surg Endosc 19:720-3. 2005..The present study was designed to examine whether a reduction of blood flow achieved by clamping or insufflation with carbon dioxide (CO(2)) would increase tumor growth in the abdominal wall.
Tracheal gas insufflation-augmented continuous positive airway pressure in a spontaneously breathing model of neonatal respiratory distressThomas L Miller
Nemours Research Lung Center, Nemours Children s Clinic Wilmington, Nemours Foundation, Alfred I duPont Children s Hospital, Delaware 19803, USA
Pediatr Pulmonol 38:386-95. 2004..However, CO2 retention during CPAP often results in the need for mechanical ventilation. Since tracheal gas insufflation (TGI) promotes CO2 elimination by reducing prosthetic dead space, we hypothesized that TGI used with CPAP may ..
Carbon dioxide embolism during laparoscopic cholecystectomy due to a patent paraumbilical veinPeter Mattei
Pediatric General, Thoracic and Fetal Surgery, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Pediatr Surg 42:570-2. 2007..cause is inadvertent injection of carbon dioxide into a large vein or solid organ during initial peritoneal insufflation. We describe a case of carbon dioxide embolism in a 13-year-old boy during an elective laparoscopic ..
Pathogenesis of CO(2) pneumoperitoneum-induced metabolic hypoxemia in a rabbit modelOspan A Mynbaev
Centre for Surgical Technologies, K.U. Leuven, Minderbroederstraat 17, B-3000 Leuven, Belgium
J Am Assoc Gynecol Laparosc 9:306-14. 2002..optimal ventilation without pneumoperitoneum, and with pneumoperitoneum at low (6 mm Hg) and higher (10 mm Hg) insufflation pressures were compared...
Effect of pneumoperitoneum on hemodynamics and inspiratory pressures during natural orifice transluminal endoscopic surgery (NOTES): an experimental, controlled study in an acute porcine modelS von Delius
2nd Medical Department, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany
Endoscopy 39:854-61. 2007..This experimental study assessed the effect of pneumoperitoneum induced by endoscope air pump on hemodynamics and inspiratory pressures during transgastric peritoneoscopy...
The effect of warm humidified CO2 on the dissipation of residual gas following laparoscopy in pigletsPeter A Glew
Department of Anesthesia, University of Otago, Dunedin, New Zealand
J Am Assoc Gynecol Laparosc 11:204-10. 2004STUDY OBJECTIVE: To determine whether residual gas volume reduces more quickly after insufflation with humidified CO(2) compared with dry CO(2). DESIGN: Animal study (Canadian Task Force classification I). SETTING: University...
A versatile dual-channel carbon dioxide (CO2) insufflator for various CO2)applications. The prototypeK Nakajima
Department of Surgery E1, Osaka University Graduate School of Medicine, 2 2, Yamadaoka, Suita Osaka, 565 0871, Japan
Surg Endosc 20:334-8. 2006..However, CO2 insufflation has not gained wide clinical acceptance, mainly because there has been no suitable feeding system...
Effect of intraabdominal pressure elevation and positioning on hemodynamic responses during carbon dioxide pneumoperitoneum for laparoscopic donor nephrectomy: a prospective controlled clinical studyI R A M Mertens zur Borg
Department of Anesthesiology, Erasmus University Medical Center, P O Box 2040, 3000, Rotterdam, CA, The Netherlands
Surg Endosc 18:919-23. 2004..This study evaluated the hemodynamic effects of elevated intraabdominal pressure (IAP) occurring during laparoscopic donor nephrectomy (LDN)...
Fewer adhesions induced by laparoscopic surgery?C N Gutt
Department of General, Visceral and Trauma Surgery, Ruprecht Karls University, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany
Surg Endosc 18:898-906. 2004..Laparoscopic surgery has potential theoretical advantages over open surgery in reducing the rate of adhesion formation, but very few comparative studies are available to prove this...
Cardiac and hemodynamic changes during carbon dioxide pneumoperitoneum for laparoscopic gynecologic surgery in Rajavithi HospitalWiboon Kamolpornwijit
Gynecologic Endoscopy Unit, Department of Obstetrics and Gynecology, Rajavithi Hospital, Bangkok 10400, Thailand
J Med Assoc Thai 91:603-7. 2008To study the effects of intraperitoneal CO2 insufflation on cardiopulmonary variables in gynecological laparoscopic patients.
Local and systemic impact of pneumoperitoneum on prepuberal ratsAlfonso Papparella
Department of Pediatric, Pediatric Surgery Unit, Second University of Naples, Via Pansini 5, 80131 Naples, Italy
Pediatr Surg Int 23:453-7. 2007..The aim of this study was to verify the effects of intra-abdominal carbon dioxide (CO(2)) and air insufflation on the peritoneum, as well as the cortico-surrenal response in prepuberal rats...
Microsphere intestinal blood flow analysis during pneumoperitoneum using carbon dioxide and heliumD Goitein
Department of Surgery, The Western Pennsylvania Hospital, Temple University School of Medicine, Clinical Campus, 4800 Friendship Avenue, Pittsburgh, PA 15224, USA
Surg Endosc 19:541-5. 2005..Different colored microspheres were injected directly into the left ventricle before, 40, 80, and 120 min after insufflation with either gas at a pressure of 15 mmHg...
Morphological changes in hepatic vascular endothelium after carbon dioxide pneumoperitoneum in a murine modelK Izumi
Department of Surgery I, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasama machi, Oita 879 5593, Japan
Surg Endosc 19:554-8. 2005..In the present study, we used scanning electron microscopy (SEM) to investigate morphological changes in hepatic vascular endothelium after CO2 pneumoperitoneum in a murine model...
[Arterial to end-tidal carbon dioxide tension difference during laparoscopic colorectal surgery]Tomoharu Tanaka
Department of Anesthesia, National Hospital Organization Kyoto Medical Center, Kyoto 612-8555
Masui 55:988-91. 2006..But deltaa-ET(CO2) may change during laparoscopic surgery, because peritoneal insufflation of CO2 will increase CO2 production and reduce functional residual volume...
The immunomodulatory effects of laparoscopic surgeryMark Corrigan
Department of Academic Surgery, Cork University Hospital, Wilton, Cork, Ireland
Surg Laparosc Endosc Percutan Tech 17:256-61. 2007..Although the initial investigations into the immunological effects of laparoscopy are encouraging, many of the intricacies associated with this approach still await elaboration...
Early peritoneal macrophage function after laparoscopic surgery compared with laparotomy in a mouse modeU Moehrlen
Department of Pediatric Surgery, University Children's Hospital, Steinwiesstrasse 75, Zurich, CH-8032, Switzerland
Surg Endosc 19:958-63. 2005..divided into five groups: anesthesia only, abdominal skin incision, laparotomy, peritoneal carbon dioxide (CO2) insufflation, and peritoneal air insufflation...
Stepwise rising CO2 insufflation as an ischemic preconditioning methodDursun A Sahin
Department of General Surgery, Afyonkarahisar Kocatepe University, School of Medicine, Afyonkarahisar, Turkey
J Laparoendosc Adv Surg Tech A 17:723-9. 2007..In this experimental, randomized, controlled trial with a blind assessment of the outcome, we evaluated the effects of a new IP method, stepwise rising CO(2) insufflation, on oxidative stress and inflammatory cytokine response.
Influence of different pneumoperitoneal pressures on tumor cell distribution in ratsH Nakada
Department of Surgery, Saitama Medical Center, Saitama Medical School, 1981 Kamoda Kawagoe, Saitama 350-8550, Japan
Surg Endosc 19:563-8. 2005..CONCLUSIONS: These results suggest that an elevated insufflation pressure facilitates the location of intraportally injected tumor cells in the liver, and that pulmonary ..
Effect of body habitus and parity on insufflated CO2 volume at various intraabdominal pressures during laparoscopic access in womenBasim Abu-Rafea
St Joseph s Health Care, Department of Obstetrics and Gynecology, The University of Western Ontario, London, Ontario, Canada
J Minim Invasive Gynecol 13:205-10. 2006..To determine height, weight, body mass index (BMI), parity, and age effect on the volume of CO2 pneumoperitoneum during laparoscopic access in women...
[Laparoscopy under local anaesthesia and hypnoanaesthesia about 35 cholecystectomies and 15 inguinal hernia repair]T Séfiani
Service d Anesthésie, Centre hospitalier de Saint Junien, 87200 Saint Junien, France
Ann Fr Anesth Reanim 23:1093-101. 2004..To present hypnosedation and the feasibility of this technique performed for laparoscopic procedure...
Evaluation of intra-abdominal pressures and gas embolism during laparoscopic partial nephrectomy in a porcine modelKyle J Weld
Division of Urologic Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA
J Urol 174:1457-9. 2005..IAP was increased in 5 mm Hg increments in 4 pigs each by 1) insufflation pressure adjustment to a maximum of 30 mm Hg and 2) intermittent application of an argon beam coagulator (ABC) ..
Effects of pneumoperitoneal gases and pressures on transitional cell carcinoma adhesion, growth, apoptosis and necrosis: an in vitro studyBeng Jit Tan
Department of Urology, Long Island Jewish Medical Center, New Hyde Park, New York 11040-1496, USA
J Urol 174:1463-7. 2005PURPOSE: We studied the effects of insufflation gas and pressure on the adhesion, growth, apoptosis and necrosis of transitional cell carcinoma (TCC) in an in vitro model...
The effects of intraabdominally insufflated carbon dioxide on hepatic blood flow during laparoscopic surgery assessed by transesophageal echocardiographyRainer Meierhenrich
Department of Anesthesiology, University of Ulm, Steinhovelstrasse 9, 89075 Ulm, Germany
Anesth Analg 100:340-7. 2005..Five minutes after insufflation of CO(2) the median right hepatic blood flow index increased from 196 mL/min/m(2) (95% confidence interval (CI),..
Cardiovascular autonomic function in patients with hemodynamic instability at induction of capnoperitoneum: a case-control studyA Alijani
Department of Surgery, Ninewells Hospital and Medical School, DD1 9SY, Dundee, Scotland, UK
Surg Endosc 18:915-8. 2004..CONCLUSIONS: Patients in whom bradycardia and hypotension develop with induction of positive-pressure capnoperitoneum have cardiovascular autonomic dysfunction, which is identifiable by bedside stress tests of autonomic function...
Effects of abdominal Co2 insufflation on renal and hepatic blood flows during acute hemorrhage in anesthetized pigsC M Pastor
, , Geneva, Switzerland
Crit Care Med 29:1017-22. 2001..during hemorrhage, we studied the respiratory, renal, and hepatic blood flow changes induced by abdominal Co2 insufflation during severe hemorrhage in anesthetized pigs. DESIGN: Prospective animal study...
Impact of carbon dioxide and helium insufflation on cardiorespiratory function during prolonged pneumoperitoneum in an experimental rat modelE J Hazebroek
Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
Surg Endosc 16:1073-8. 2002..the aim of this study was to investigate in spontaneously breathing rats the effects of CO2 and helium, insufflation pressure, and duration of pneumoperitoneum on blood pressure, arterial pH, pCO2, pO2, HCO3-, base excess, and ..
Variables in the spread of tumor cells to trocars and port sites during operative laparoscopyS M Brundell
Department of Surgery, University of Adelaide, The Queen Elizabeth Hospital, Woodville South, South Australia
Surg Endosc 16:1413-9. 2002..In the first study, tumor inocula were varied from 1.5 x 10(5) to 120 x 10(5). In the second study, insufflation pressure was varied, with pressures 0, 4, 8 and 12 mmHg were studied...
[Subarachnoid anesthesia in the repair of urinary stress incontinence using a Burch-type colposuspension by means of extraperitoneal laparoscopy]P de Santos
Servicio de Anestesiologia, Reanimación y Tratamiento del Dolor, Universidad de Barcelona, C Villarroel no 170, 08036 Barcelona
Rev Esp Anestesiol Reanim 49:76-9. 2002..Therefore, subarachnoid anesthesia might possibly be appropriate for this type of procedure...
Impact of dopamine and endothelin-1 antagonism on portal venous blood flow during laparoscopic surgeryZ-G Kim
Department of General and Vascular Surgery, Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, D-60590 Frankfurt/Main, Germany
Surg Endosc 16:1292-6. 2002BACKGROUND: Recent data indicate that pneumoperitoneal carbondioxide (CO2) insufflation impairs hepatic macro- and microcirculation...
Peritoneal, systemic, and distant organ inflammatory responses are reduced by a laparoscopic approach and carbon dioxide versus airB M Ure
Department of Pediatric Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
Surg Endosc 16:836-42. 2002..The objective of the study was to determine the impact of laparoscopy and laparotomy with exposure to CO2 and room air under a similar pressure on local, systemic, and distant organ immune responses...
The effects of increased intraabdominal pressure on colonic anastomosesC Polat
Department of General Surgery, Afyon Kocatepe University, Afyon, Turkey
Surg Endosc 16:1314-9. 2002..This experimental, randomized, controlled study was designed to investigate the effects of increased intraabdominal pressure (IAP) on colocolic anastomoses. To our knowledge, this is the first study to address this important issue...
The effect of insufflation pressure on CO(2) pneumoperitoneum and embolism in pigletsDavid S Beebe
Department of Anesthesiology, University of Minnesota Medical School, Minneapolis, Minnesota 55435, USA
Anesth Analg 94:1182-7, table of contents. 2002We conducted this study to investigate the effect of insufflation pressure on the pathophysiology of CO(2) pneumoperitoneum and embolism in an infant model...
Mechanical ventilation with positive end-expiratory pressure preserves arterial oxygenation during prolonged pneumoperitoneumE J Hazebroek
Department of Surgery, Erasmus Medical Center, Rotterdam, Rotterdam, The Netherlands
Surg Endosc 16:685-9. 2002..The objective of this study was to investigate the effect of abdominal gas insufflation on arterial oxygenation during mechanical ventilation with and without PEEP in rats...
Tracheal gas insufflation during late exhalation efficiently reduces PaCO(2) in experimental acute lung injuryChristopher Carter
Regions Hospital, Pulmonary Research, 640 Jackson Street, St. Paul, MN 55101, USA
Intensive Care Med 28:504-8. 2002OBJECTIVE: Tracheal gas insufflation (TGI) reduces PaCO(2) by flushing the tracheal and mechanical deadspace, and may have its maximum benefit when TGI gas is unopposed by significant expiratory gas flow...
The effects of vasoactive drugs on hepatic blood flow changes induced by CO2 laparoscopy: an animal studyM Agusti
Department of Anesthesia URSC, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
Anesth Analg 93:1121-6. 2001..A small-dose infusion of neither dobutamine nor dopamine corrects the total hepatic blood flow impairment, but the former is able to restore the hepatic arterial blood supply in an animal model mimicking this condition...
Effects of helium pneumoperitoneum in pregnant ewesM J Curet
Department of Surgery, ACC-2, University of New Mexico School of Medicine, 2211 Lomas Boulevard NE, Albuquerque, NM, 87131, USA
Surg Endosc 15:710-4. 2001..Therefore, He may be a safer gas than CO(2) to use for laparoscopic procedures in pregnant patients...
Carbon dioxide pneumoperitoneum reduces levels of TNF-a mRNA in the brain, liver, and peritoneum in miceH Kamei
Department of Surgery, School of Medicine, Kurume University, Kurume, Fukuoka 830-0011, Japan
Surg Endosc 15:609-13. 2001..METHODS: Mice were randomly assigned to one of six groups: control, anesthesia alone, insufflation with carbon dioxide, insufflation with air, laparotomy by short incision, or laparotomy by long incision...
The impact of gas laparoscopy on abdominal plasminogen activator activityM Nagelschmidt
Second Department of Surgery, Biochemical and Experimental Division, University of Cologne, Ostmerheimer Strasse 200, 51109 Cologne, Germany
Surg Endosc 15:585-8. 2001..A 15 mmHg pneumoperitoneum was established for 3 h by the insufflation of carbon dioxide (group 2, n = 6) or helium (group 3, n = 6). Group 1 (n = 7) received no gas insufflation...
Morphology of the murine peritoneum after pneumoperitoneum vs laparotomyT Suematsu
Department of Surgery I, Oita Medical University, 1-1 Idaigaoka, Hasama-machi, Oita 879-5593, Japan
Surg Endosc 15:954-8. 2001..from those after laparotomy and were influenced by the type of gas, amount of pressure, and duration of insufflation. These peritoneal changes after pneumoperitoneum may be associated with a specific intraperitoneal tumor spread ..
Effects of intraperitoneal and extraperitoneal carbon dioxide insufflation on blood gases during the perioperative periodSener Demiroluk
University of Istanbul, Medical School of Cerrahpasa, Istanbul, Turkey
J Laparoendosc Adv Surg Tech A 14:219-22. 2004The aim of this study was to evaluate the effects of intraperitoneal and extraperitoneal CO2 insufflation on blood gases during and after laparoscopic surgery. Forty patients were included in this study...
Research Grants
- TRACHEAL GAS INSUFFLATION - PATIENT INTERFACE SYSTEMROBERT VIRAG; Fiscal Year: 2004The benefits of Tracheal Gas Insufflation (TGI) as an adjunct to mechanical ventilation are well known...
- Utilizing Ethyl Nitrate Gas in Laparoscopic SurgeryJames Reynolds; Fiscal Year: 2006..In addition, due to its plasma solubility, insufflation with CO2 will increase pCOz and decrease blood pH, actions that can produce respiratory acidosis, tachycardia, ..
- THE ESOPHAGOGASTRIC JUNCTION IN HEALTH AND DISEASEPeter Kahrilas; Fiscal Year: 2005..of gastric distension and to ascertain EGJ compliance during fluoroscopy of the EGJ, using intragastric air insufflation to study the physiology of transient LES relaxations and high resolution manometry to map the geometry and ..
- THE ROLE OF SELECTINS IN BURNS AND INHALATION INJURYDaniel Traber; Fiscal Year: 2003..antibodies to the selectins will effect the cardiopulmonary sequelae seen with burns in combination with smoke insufflation. 3...
- UPPER AIRWAY CONTROL OF TRANSTRACHEAL INSUFFLATIONAlan Schwartz; Fiscal Year: 2003..proposal, we outline a potentially novel approach for treating apneic patients with high flow transtracheal insufflation (hf-TTI), a method for delivering airflow to the trachea through a thin cannula...
- PULMONARY MASS AND HEAT TRANSPORTJames Grotberg; Fiscal Year: 2002..In the first project pulmonary gas transport during intra-tracheal insufflation (ITI), with or without external chest vibrations, will be studied to investigate ITI as a means of enhancing ..
- Quantifying Left Ventricular Ejection EffectivenessMichael Pinsky; Fiscal Year: 2007..The ultimate goal of this proposal is to develop and validate an echocardiographic-based algorithm that quantifies LV ejection effectiveness by merging both power and synchrony of contraction into a common metric. ..
- TRPV4 Initiates Ventilator Induced Lung InjuryJames Parker; Fiscal Year: 2009..and that lung PAR1 and PAR2 activation peptidesincrease lung vascular permeability in TRPV4+/+ mice ventilated with high airway pressures but not in TRPV4-/- mice, or either genotype ventilated with low airway pressures ..
- Multicenter Trial of Fetal Myelomeningocele RepairJohn Brock; Fiscal Year: 2006..In summary, the proposed trial is expected to demonstrate whether fetal intervention offers improved outcome with a reasonable quality of life for spina bifida children. ..
- AIRWAY PROTECTION DURING VOMITINGIvan Lang; Fiscal Year: 2002..Finally, the relative contribution of peripheral reflexes and direct central nervous system control over the motor events that comprise vomiting will be studied. ..
- AIRWAY PERFUSION ASSISTED LIQUID VENTILATORJames Parker; Fiscal Year: 2002..Other applications include continuous intrapulmonary administration of drugs and anesthetics and clearance of material from the lungs...
- Non-Surgical Device for Treatment of Middle Ear EffusionShlomo Silman; Fiscal Year: 2002..Although the custom-made device costs $325 including product liability, when commercially produced, it will cost about $5.00. ..
- Mechanical Injury to Lung EndotheliumJames Parker; Fiscal Year: 2001....
- Peptides surface modification to prevent stent blockageJoseph Leung; Fiscal Year: 2006..The results may shed new lights in the prevention of chronic implanted medical device related infections and specifically in prolonging plastic stent patency. ..
- Role of Estrogen in Exercise-Induced VEGF ExpressionPauline Entin; Fiscal Year: 2003..The results of this study will contribute to the assessment of the risk/benefit ratio for hormone replacement therapy, particularly in the context of those at risk for cardiovascular disease. ..
- TRPV4 Initiates Ventilator Induced Lung InjuryJames C Parker; Fiscal Year: 2010..and that lung PAR1 and PAR2 activation peptidesincrease lung vascular permeability in TRPV4+/+ mice ventilated with high airway pressures but not in TRPV4-/- mice, or either genotype ventilated with low airway pressures ..
