Summary: The act of blowing a powder, vapor, or gas into any body cavity for experimental, diagnostic, or therapeutic purposes.
Publications229 found, 100 shown here
- NORCCAP (Norwegian colorectal cancer prevention): a randomised trial to assess the safety and efficacy of carbon dioxide versus air insufflation in colonoscopyM Bretthauer
NORCCAP Centre, Telemark Central Hospital, Porsgrunn, Norway Department of Anaesthesiology, Telemark Central Hospital, Porsgrunn, Norway
Gut 50:604-7. 2002..the risk of combustion during electrosurgical procedures and to reduce patient discomfort, carbon dioxide (CO2) insufflation has been recommended during colonoscopy...
- Randomized, controlled trial of carbon dioxide insufflation during colonoscopyJ Church
Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Dis Colon Rectum 46:322-6. 2003b>Insufflation of air is a cause of discomfort during and after colonoscopy. Although this can be minimized by good technique, the use of carbon dioxide insufflation may provide further benefits...
- Automated insufflation of carbon dioxide for MDCT colonography: distension and patient experience compared with manual insufflationDavid Burling
Department of Intestinal Imaging, St Mark s and Northwick Park Hospitals, Harrow HA1 3UJ, UJK
AJR Am J Roentgenol 186:96-103. 2006The purpose of our study was to compare the effects of automated and manual carbon dioxide insufflation before CT colonography on distention and patient acceptance.
- Constant flow insufflation of oxygen as the sole mode of ventilation during out-of-hospital cardiac arrestCatherine Bertrand
Henri Mondor Hospital, Paris 12 University, Department of Anesthesiology and Emergency Medical Service of Creteil, AP HP, Creteil, France
Intensive Care Med 32:843-51. 2006Constant flow insufflation of oxygen (CFIO) through a Boussignac multichannel endotracheal tube has been reported to be an efficient ventilatory method during chest massage for cardiac arrest.
- Sympathetic and cardiovascular responses to glossopharyngeal insufflation in trained apnea diversKarsten Heusser
Institute of Clinical Pharmacology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
J Appl Physiol (1985) 109:1728-35. 2010Glossopharyngeal insufflation (lung packing) is a common maneuver among experienced apnea divers by which additional air is pumped into the lungs. It has been shown that packing may compromise cardiovascular homeostasis...
- Carbon dioxide insufflation improves intubation depth in double-balloon enteroscopy: a randomized, controlled, double-blind trialD Domagk
Department of Medicine B, University Hospital of Munster, Munster, Germany
Endoscopy 39:1064-7. 2007..However, intubation depth is limited by distention of the small bowel due to air insufflation during the procedure...
- Automated carbon dioxide insufflation for CT colonography: effectiveness of colonic distention in cancer patients with severe luminal narrowingSo Yeon Kim
Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 388 1 Poongnap dong, Songpa Gu, 138 040 Seoul, Korea
AJR Am J Roentgenol 190:698-706. 2008The objective of our study was to determine the effectiveness of automated CO2 insufflation in colonic distention for CT colonography (CTC) in patients with severe luminal narrowing by colorectal cancer and preliminarily evaluate its ..
- Lung insufflation capacity in neuromuscular diseaseJohn Robert Bach
Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey, USA
Am J Phys Med Rehabil 87:720-5. 2008To compare maximal passive lung insufflation capacity (LIC) with lung inflation by air stacking (to maximum insufflation capacity [MIC]) and with vital capacity (VC); to explore relationships between these variables that correlate with ..
- Tracheal gas insufflation-augmented continuous positive airway pressure in a spontaneously breathing model of neonatal respiratory distressThomas L Miller
Nemours Research Lung Center, Nemours Children s Clinic Wilmington, Nemours Foundation, Alfred I duPont Children s Hospital, Delaware 19803, USA
Pediatr Pulmonol 38:386-95. 2004..However, CO2 retention during CPAP often results in the need for mechanical ventilation. Since tracheal gas insufflation (TGI) promotes CO2 elimination by reducing prosthetic dead space, we hypothesized that TGI used with CPAP may ..
- Study of the effectiveness of bronchial clearance in subjects with upper spinal cord injuries: examination of a rehabilitation programme involving mechanical insufflation and exsufflationP Pillastrini
Department of Neurological Sciences, Rehabilitative Sciences S S D MED 48, University of Bologna, Bologna, Italy
Spinal Cord 44:614-6. 2006..Randomized controlled trial...
- CO2 environment influences the growth of cultured human cancer cells dependent on insufflation pressureC N Gutt
Department of General and Vascular Surgery, Johann Wolfgang Goethe University, Theodor Ster Kai 7, Frankfurt Main, Germany
Surg Endosc 15:314-8. 2001..Previous experiments performed both in vitro and in vivo have proved that CO2 insufflation stimulates malignant cell growth...
- Performance of the coughassist insufflation-exsufflation device in the presence of an endotracheal tube or tracheostomy tube: a bench studyClaude Guerin
Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, Lyon, France
Respir Care 56:1108-14. 2011..The device may benefit intubated and tracheotomized patients. We assessed the impact of various artificial airways on peak expiratory flow (PEF) with the CoughAssist...
- Helium and other alternative insufflation gases for laparoscopyS J Neuhaus
Department of Surgery, The University of Adelaide, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia 5000, Australia
Surg Endosc 15:553-60. 2001BACKGROUND: Carbon dioxide (CO(2)) is currently the insufflation gas of choice for laparoscopy. It fulfills most of the requirements for an ideal insufflation gas, being colorless, noninflammable, and rapidly excreted from the circulation...
- The effects of different insufflation pressures on liver functions assessed with LiMON on patients undergoing laparoscopic cholecystectomyH Barıs Eryılmaz
Department of Anaesthesiology and Reanimation, Trakya University Medical Faculty, 22030 Edirne, Turkey
ScientificWorldJournal 2012:172575. 2012..We assessed the effects of different insufflation pressures on liver functions by using indocyanine green elimination tests (ICG-PDR).
- Mechanical insufflation-exsufflation device prescription for outpatients with tetraplegiaJames D Crew
Spinal Cord Injury Service, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA
J Spinal Cord Med 33:128-34. 2010Mechanical insufflation-exsufflation (MIE) is an option for secretion mobilization in outpatients with spinal cord injury (SCI) who lack an effective cough and are at high risk for developing pneumonia.
- Patient-controlled room air insufflation versus automated carbon dioxide delivery for CT colonographyTheodore J Shinners
Department of Radiology, University of Wisconsin Medical School, Clinical Science Center, 600 Highland Ave, Madison, WI 53792, USA
AJR Am J Roentgenol 186:1491-6. 2006Our objective was to prospectively compare colonic distention and patient comfort at screening CT colonography (CTC) with patient-controlled room air (RA) insufflation versus automated carbon dioxide (CO2) delivery.
- Continuous intratracheal insufflation of oxygen improves the efficacy of mechanical chest compression-active decompression CPRStig Steen
Department of Cardiothoracic Surgery, Heart Lung Division, University Hospital of Lund, SE 221 85 Lund, Sweden
Resuscitation 62:219-27. 2004The aim of the present study was to compare the efficacy of intratracheal continuous insufflation of oxygen (CIO) with intermittent positive pressure ventilation (IPPV) regarding gas exchange and haemodynamics during mechanical chest ..
- Mechanical insufflation-exsufflation: pressure, volume, and flow relationships and the adequacy of the manufacturer's guidelinesElia Gomez-Merino
Pneumology Department, Hospital Clínico Universitario Sant Joan d Alacant, Alicante, Spain
Am J Phys Med Rehabil 81:579-83. 2002..The purpose of this study was to examine the pressure, volume, and flow relationships for a range of settings generated by this device, and compare them with clinically efficacious values and the manufacturer's guidelines...
- Reliable and effective oxygen-ozone therapy at a crossroads with ozonated saline infusion and ozone rectal insufflationVelio Bocci
Dip di Fisiologia, Universita degli Studi di Siena, Siena, Italy
J Pharm Pharmacol 64:482-9. 2012..This review aims to highlight the advantages and safety of oxygen-ozone therapy (OOT) and to suggest ways to enhance its acceptance...
- Prolonged carbon dioxide insufflation under general anesthesia for endoscopic submucosal dissectionT Suzuki
Department of Anesthesia, Showa University Northern Yokohama Hospital, Yokohama, Kanagawa, Japan
Endoscopy 42:1021-9. 2010Carbon dioxide (CO (2)) insufflation for endoscopy has been reported to provide superior recovery and is expected to reduce the risk of serious complications, including air embolism and tension pneumothorax, whereas general anesthesia ..
- Chitosan microspheres as a delivery system for nasal insufflationSanjay B Patil
Shri Neminath Jain Brahmacharyashram s, Shriman Sureshdada Jain College of Pharmacy PG Course, Neminagar, Chandwad, Dist Nashik 423 101, Maharashtra, India sbpatil
Colloids Surf B Biointerfaces 84:384-9. 2011..The core of the clouds was homogeneous which can be expected to provide effective distribution pattern...
- Impact of laparoscopic CO2-insufflation on tumor-associated molecules in cultured colorectal cancer cellsZ G Kim
Department of General and Vascular Surgery, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt Main, Germany
Surg Endosc 16:1182-6. 2002Laparoscopic CO2-insufflation is believed to stimulate proliferation and metastatic potential of gastrointestinal carcinomas. E-cadherin, I-CAM1, I-CAM2, and CD44 are involved into the metastatic process of different cancer cell lines...
- Experimental study of peritoneal blood flow and insufflation pressure during laparoscopyS M Brundell
Department of Surgery, University of Adelaide, The Queen Elizabeth Hospital, Woodville South, Australia
Br J Surg 89:617-22. 2002..The possibility that insufflation may increase peritoneal blood flow producing a wound environment conducive to the formation of metastases was ..
- Pneumothorax associated with mechanical insufflation-exsufflation and related factorsPradeep Suri
Department of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA
Am J Phys Med Rehabil 87:951-5. 2008..Mechanical insufflation-exsufflation (MI-E) is a respiratory aid used by patients with weak respiratory muscles to increase cough peak ..
- Higher CO2-insufflation pressure inhibits the expression of adhesion molecules and the invasion potential of colon cancer cellsJun Jun Ma
Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Minimally Invasive Surgery Center, Shanghai, China
World J Gastroenterol 15:2714-22. 2009To investigate the influence of CO(2)-insufflation pressure on adhesion, invasion and metastatic potential of colon cancer cells based on adhesion molecules expression.
- Lung injury following thoracoscopic talc insufflation: experience of a single North American centerAnne V Gonzalez
Montreal Chest Institute, McGill University Health Centre, 3650 Saint Urbain St K1 09, Montreal, QC, Canada H2X 2P4
Chest 137:1375-81. 2010Thoracoscopic talc insufflation (TTI) has been used to obliterate the pleural space and prevent recurrent pleural effusions or pneumothorax. Reports of acute pneumonitis and ARDS after the use of talc raised concern about its safety...
- Increased insufflation pressure enhances the development of liver metastasis in a mouse laparoscopy model: possible mechanismsH Ishida
Department of Surgery, Saitama Medical Center, Saitama Medical School, 1981 Kamoda Kawagoe, Saitama 350 8550, Japan
Surg Endosc 16:331-5. 2002The effect of different insufflation pressures and durations of CO2 pneumoperitoneum on the growth of liver metastasis was investigated in a mouse model...
- Mechanical insufflation-exsufflation improves outcomes for neuromuscular disease patients with respiratory tract infectionsAndrea Vianello
Unità di Terapia Semi Intensiva Respiratoria, Azienda Ospedaliera di Padova, Padova, Italy
Am J Phys Med Rehabil 84:83-8; discussion 89-91. 2005The efficacy of mechanical insufflation-exsufflation, in addition to standard chest physical treatments, was investigated as a first-line intervention for patients with neuromuscular diseases with respiratory tract infections and airway ..
- Effects of mechanical insufflation-exsufflation on respiratory parameters for patients with chronic airway secretion encumbranceJoão C Winck
Pneumology Department, Hospital Sao Joao, Faculdade de Medicina, Universidade do Porto Porto, Portugal
Chest 126:774-80. 2004To analyze the physiologic effects and tolerance of mechanical insufflation-exsufflation (MI-E) for patients with chronic ventilatory failure of various etiologies.
- Outcome of goal-directed non-invasive ventilation and mechanical insufflation/exsufflation in spinal muscular atrophy type IM Chatwin
Sleep and Ventilation Unit, Clinical and Academic Department of Sleep and Breathing, Royal Brompton Hospital, Sydney Street, London, UK
Arch Dis Child 96:426-32. 2011..There are widely discrepant views on the respiratory management of infants with spinal muscular atrophy (SMA) type I. Typically, management is palliative...
- Effects of CO2 insufflation on cerebrum during endoscopic thyroidectomy in a porcine modelWenbin Yu
Department of General Surgery, Qilu Hospital of Shandong University, Wenhua Xi Road 107, Jinan, 250012, Shandong, People s Republic of China
Surg Endosc 25:1495-504. 2011The operative cavity during endoscopic thyroidectomy is maintained mainly by CO2 insufflation. We designed this study to explore the effects of CO2 insufflation on the cerebrum during endoscopic thyroidectomy in a porcine model.
- Renal effects of carbon dioxide insufflation in rabbit pneumoretroperitoneum modelC Guler
Department of Urology, Dokuz Eylul University School of Medicine, Inciralti Izmir, Turkey
J Endourol 12:367-70. 1998To determine the effects of carbon dioxide insufflation on renal function in a pneumoretroperitoneum model, 24 adult New Zealand rabbits were divided into four groups, six rabbits in each...
- Actual colonic perforation in virtual colonoscopy: report of a caseMoshe Kamar
Department of Surgery and Transplantation, Sheba Medical Center, Tel Hashomer, Israel
Dis Colon Rectum 47:1242-4; discussion 1244-6. 2004..Thus, it is suggested that in such cases, air insufflation should be gradual, thereby minimizing the risk of perforation.
- Perforated colon secondary to virtual colonoscopy: report of a caseLoretta Coady-Fariborzian
Division of Colon and Rectal Surgery, Department of Surgery, North Shore University Hospital, Manhasset, New York, USA
Dis Colon Rectum 47:1247-9. 2004..The pathologic findings were described as ulcerative colitis with full-thickness perforation. To the best of our knowledge, this is the first complication from a virtual colonoscopy reported in the literature...
- The effect of insufflation pressure on pulmonary mechanics in infants during laparoscopic surgical proceduresCarolyn F Bannister
Assistant Professor of Anesthesiology and Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
Paediatr Anaesth 13:785-9. 2003..We objectively measured the pulmonary effects of laparoscopically-induced pneumoperitoneum in infants less than 1 year of age undergoing surgical procedures under general anaesthesia...
- Carbon dioxide insufflation compared with air insufflation in double-balloon enteroscopy: a prospective, randomized, double-blind trialFumihito Hirai
Department of Gastroenterology, Fukuoka University Chikushi Hospital, 1 1 1, Zokumyoin, Chikushino, Japan
Gastrointest Endosc 73:743-9. 2011Few studies have evaluated the degree of pain, the amount of retained gas, and the safety of carbon dioxide (CO(2)) insufflation in patients undergoing double-balloon enteroscopy (DBE).
- Effects of intra-abdominal CO2-insufflation on normal and impaired myocardial function: an experimental studyC A Greim
Klinik fur Anaesthesiologie, Universitatsklinikum Wurzburg, Germany
Acta Anaesthesiol Scand 47:751-60. 2003..This study focused on the effects of acute IAP increases on left and right ventricular loadings and contractility in the heart with impaired global function...
- Helium vs carbon dioxide gas insufflation with or without saline lavage during laparoscopyC J O'Boyle
University of Adelaide, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia 5000, Australia
Surg Endosc 16:620-5. 2002Helium is an inert gas that, if used for insufflation during laparoscopy, may be followed by less postoperative pain than carbon dioxide (CO2) insufflation, due to a more limited effect on intraabdominal pH and metabolism...
- Cough augmentation with mechanical insufflation/exsufflation in patients with neuromuscular weaknessM Chatwin
Sleep and Ventilation Unit, Royal Brompton Hospital, London, UK
Eur Respir J 21:502-8. 2003..Mechanical insufflation/exsufflation may improve cough efficacy by increasing peak cough flow...
- Increasing the size limit of benign thyroid lesions resectable by endoscopic thyroidectomy via a unilateral axillo-breast approach without gas insufflationWon Shik Kim
Department of Otorhinolaryngology, Yonsei University College of Medicine, 134 Shinchon dong, Seodaemun gu, Seoul 120 752, Korea
World J Surg 35:2203-11. 2011..We examined the feasibility and safety of endoscopic thyroidectomy via a unilateral axillo-breast approach without gas insufflation for resection of large thyroid tumors (≥4 cm).
- Meta-analysis: the use of carbon dioxide insufflation vs. room air insufflation for gastrointestinal endoscopyW L Wang
Key Laboratory of Combined Multi organ Transplantation, Ministry of Public Health, Hangzhou, China
Aliment Pharmacol Ther 35:1145-54. 2012Carbon dioxide (CO(2)) insufflation has been proposed as an alternative to air insufflation to distend the lumen in gastrointestinal (GI) endoscopy.
- Randomized comparison between different insufflation pressures for laparoscopic cholecystectomyE Perrakis
Department of Surgery, Western Attica General Hospital, Athens, Greece
Surg Laparosc Endosc Percutan Tech 13:245-9. 2003Laparoscopy using carbon dioxide insufflation induces adverse effects in both the cardiovascular and the respiratory function. The use of low pressure pneumoperitoneum has been shown to reduce adverse hemodynamic effects...
- Amniotic air insufflation during minimally invasive fetoscopic fetal cardiac interventions is safe for the fetal brain in sheepThomas Kohl
Division of Obstetrics and Prenatal Medicine, University Hospital of Bonn, Bonn, Germany
J Thorac Cardiovasc Surg 128:467-71. 2004Amniotic air insufflation during experimental fetoscopic fetal cardiac interventions greatly improves the visualization of intra-amniotic contents...
- Carbon dioxide insufflation during withdrawal of the colonoscope improved postprocedure discomfort: a prospective, randomized, controlled trialWen Hsin Hsu
Division of Gastroenterology, Department of Internal Medicine, Yuan s General Hospital, Kaohsiung, Taiwan
Kaohsiung J Med Sci 28:265-9. 2012In colonoscopy, the question of when and how to use carbon dioxide (CO(2)) insufflation remains uncertain. Inspection for the pathological changes during colonoscopy takes place during the withdrawal of the scope...
- Safe and novel technique for peritoneal access in urologic laparoscopy without prior insufflationLiam Hickey
Department of Urology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
J Endourol 20:622-6. 2006..When the technique was described initially, capnoperitoneum was obtained prior to trocar insertion. We describe the results of our series using the EndoTIP port without prior capnoperitoneum...
- Effects of glossopharyngeal pistoning for lung insufflation on vital capacity in healthy womenMalin Nygren-Bonnier
Division of Physiotherapy, Department of Neurobiology, Care Science and Society, Karolinska Institutet, Sweden
Am J Phys Med Rehabil 86:290-4. 2007..to perform glossopharyngeal pistoning (GP) to insufflate the lungs to volumes exceeding maximum inspiratory capacity (IC), whether such insufflation caused discomfort, and the immediate and long-term effects on vital capacity (VC).
- Abdominal insufflation for control of bleeding after severe splenic injuryGeorge C Velmahos
Division of Trauma, Emergency Surgery, and Surgical Critical Care, Department of Surgery, The Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
J Trauma 63:285-8; discussion 288-90. 2007..Abdominal insufflation (AI) by carbon dioxide has been shown to reduce the rate of bleeding after intra-abdominal injury in pigs...
- Hyperbaric treatment of arterial CO2 embolism occuring after laparoscopic surgery: a case reportR S Reust
Oklahoma State University Center for Health Sciences, Tulsa, OK, USA
Undersea Hyperb Med 33:317-20. 2006..The HBO2 protocol was 2.8 atmospheres for 90 minutes, which resolved the problem with no adverse effects...
- A randomized, controlled comparison of warm water infusion in lieu of air insufflation versus air insufflation for aiding colonoscopy insertion in sedated patients undergoing colorectal cancer screening and surveillanceJoseph W Leung
Section of Gastroenterology, Sacramento Veterans Affairs Medical Center, Veterans Affairs Northern California Health Care System, Mather, California 95655, USA
Gastrointest Endosc 70:505-10. 2009..Pilot studies using a novel water method to perform screening colonoscopy allowed patients to complete colonoscopy without sedation medications and also significantly increased the cecal intubation success rate...
- Passive oxygen insufflation is superior to bag-valve-mask ventilation for witnessed ventricular fibrillation out-of-hospital cardiac arrestBentley J Bobrow
Arizona Department of Health Services Bureau of Emergency Medical Services and Trauma System, Phoenix, AZ, USA
Ann Emerg Med 54:656-662.e1. 2009..We compare the adjusted neurologically intact survival of out-of-hospital cardiac arrest patients receiving initial passive ventilation with those receiving initial bag-valve-mask ventilation...
- Tumour implantation following laparoscopy using different insufflation gasesAnurag Gupta
University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia
ANZ J Surg 72:254-7. 2002..studies have suggested that chemical, metabolic and immunological changes following carbon dioxide (CO2) insufflation may be responsible for this phenomenon...
- The effects of intraabdominally insufflated carbon dioxide on hepatic blood flow during laparoscopic surgery assessed by transesophageal echocardiographyRainer Meierhenrich
Department of Anesthesiology, University of Ulm, Steinhovelstrasse 9, 89075 Ulm, Germany
Anesth Analg 100:340-7. 2005..Five minutes after insufflation of CO(2) the median right hepatic blood flow index increased from 196 mL/min/m(2) (95% confidence interval (CI),..
- Reduction of carbon dioxide embolism for endoscopic saphenous vein harvestingKuan Ming Chiu
Department of Cardiovascular Surgery, Far Eastern Memorial Hospital, National Taiwan University College of Medicine, Taipei, Taiwan
Ann Thorac Surg 81:1697-9. 2006..Carbon dioxide (CO2) insufflation is used during EVH to facilitate the procedure...
- CO(2) insufflation for potentially difficult colonoscopies: efficacy when used by less experienced colonoscopistsToshio Uraoka
Department of Endoscopy, Okayama University Hospital, Kita ku, Okayama 700 8558, Japan
World J Gastroenterol 15:5186-92. 2009To clarify the effectiveness of CO(2) insufflation in potentially difficult colonoscopy cases, particularly in relation to the experience level of colonoscopists.
- The role of carbon dioxide insufflation in colonoscopy: a systematic review and meta-analysisJ Wu
Department of Endoscopy, Eastern Hepatobiliary Hospital, The Second Military Medical University, Shanghai, China
Endoscopy 44:128-36. 2012b>Insufflation of the intestinal tract, usually with room air, is necessary to improve visualization during colonoscopy. However, most patients complain of bowel distension and abdominal pain afterwards...
- High flow insufflation for the maintenance of the pneumoperitoneum during bariatric surgeryMarkos Daskalakis
Centre for Minimal Invasive Surgery, Department of General and Bariatric Surgery, Krankenhaus Sachsenhausen, Frankfurt M, Germany
Obes Facts 2:37-40. 2009....
- Coronary endothelial damage during off-pump CABG related to coronary-clamping and gas insufflationY Okazaki
Department of Thoracic and Cardiovascular Surgery, Saga Medical School, 5 1 1 Nabeshima, Saga City, 849 8501, Saga, Japan
Eur J Cardiothorac Surg 19:834-9. 2001..The present study was designed to evaluate the adverse effects of coronary snaring with looped sutures and gas insufflation on the coronary endothelium...
- The use of carbon dioxide for insufflation during GI endoscopy: a systematic reviewEvan S Dellon
Department of Medicine, Division of Gastroenterology and Hepatology, Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7080, USA
Gastrointest Endosc 69:843-9. 2009b>Insufflation of the lumen is required for visualization during GI endoscopy. Carbon dioxide (CO(2)) has been proposed as an alternative to room air for insufflation.
- Abdominal insufflation decreases blood loss without worsening the inflammatory response: implications for prehospital control of internal bleedingGeorge C Velmahos
Division of Trauma, Emergency Surgery, and Surgical Critical Care, The Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
Am Surg 74:297-301. 2008Abdominal insufflation (AI) by carbon dioxide has been shown to decrease the rate of bleeding in different swine models of abdominal organ injuries...
- Hemodynamics and gas exchange during carbon dioxide insufflation for totally endoscopic coronary artery bypass graftingC Byhahn
Department of Anesthesiology, JW Goethe University Hospital, Frankfurt, Germany
Ann Thorac Surg 71:1496-501; discussion 1501-2. 2001In addition to single-lung ventilation (SLV), positive-pressure CO2 insufflation is mandatory for totally endoscopic coronary artery bypass grafting...
- Retroperitoneoscopic living donor nephrectomy without gas insufflation: the five-year Hamamatsu University experienceKazuo Suzuki
Department of Urology, Hamamatsu University School of Medicine, 1 20 1 Handayama, Hamamatsu 431 3192, Japan
Transplant Proc 34:720-1. 2002
- Carbon dioxide insufflation for colonoscopy: evaluation of gas volume, abdominal pain, examination time and transcutaneous partial CO2 pressureHiro o Yamano
Department of Gastroenterology, Akita Red Cross Hospital, 222 1 Kami kitade saruta, Akita, Akita, 010 1495, Japan
J Gastroenterol 45:1235-40. 2010b>Insufflation with carbon dioxide (CO(2)) in colonoscopy has not been widely adopted and, consequently, limited data are available on insufflated gas volume and blood pCO(2)...
- The cardiopulmonary effects of single-lung ventilation and carbon dioxide insufflation during thoracoscopic internal mammary artery harvestingThomas A Vassiliades
Pensacola Heart Institute, Pensacola, Florida, USA
Heart Surg Forum 5:22-4. 2002..The technique involves the use of single-lung ventilation and carbon dioxide insufflation to maximize exposure and facilitate rapid dissection...
- Effects of pneumoperitoneum created through CO2 insufflation and parameters of mechanical ventilation (PEEP application) on systemic dissemination of intraabdominal infectionsU Barbaros
Department of General Surgery, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey
Surg Endosc 18:501-7. 2004..To examine whether CO2 pneumoperitoneum and positive end expiratory pressure (PEEP) in mechanical ventilation affect the systemic spread of intraabdominal infection...
- Heating of carbon dioxide during insufflation alters the peritoneal fibrinolytic response to laparoscopic surgery : A clinical trialW J A Brokelman
Department of Surgery, Alysis Zorggroep, locatie Rijnstate, Wagnerlaan 55, 6815, AD, Arnhem, The Netherlands
Surg Endosc 22:1232-6. 2008..It involves the creation of a pneumoperitoneum, mostly using carbon dioxide. Cooling of the peritoneum, due to insufflation, might traumatize the peritoneum and disturb peritoneal fibrinolysis, important in peritoneal healing processes...
- Safe laparoscopic entry guided by Veress needle CO2 insufflation pressureGeorge A Vilos
Department of Obstetrics and Gynecology, University of Western Ontario, London, Ontario, Canada
J Am Assoc Gynecol Laparosc 10:415-20. 2003..Pressures greater than 8 mm Hg indicate interstitial placement including colon. Adequate pneumoperitoneum is determined by CO2 insufflation to a pressure of 25 mm Hg and not by a preconceived volume of CO2.
- Feasibility and surgical approach of transaxillary robotic thyroidectomy without CO(2) insufflationCarol M Lewis
Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
Head Neck 32:121-6. 2010..Our objective was to evaluate the anatomic basis for robotic-assisted transaxillary thyroidectomy and to determine its feasibility in a prospective clinical trial...
- A pilot study to assess the safety and efficacy of carbon dioxide insufflation during colorectal endoscopic submucosal dissection with the patient under conscious sedationYutaka Saito
Division of Endoscopy, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
Gastrointest Endosc 65:537-42. 2007..This procedure is performed by using air insufflation, is time consuming, and is associated with severe abdominal discomfort...
- Arterial PCO2 and cardiovascular function during endoscopic neck surgery with carbon dioxide insufflationR Bellantone
Division of Endopcrine Surgery, Catholic University, Rome, Italy
Arch Surg 136:822-7. 2001..Concerns about the use of carbon dioxide insufflation in the neck exist owing to reports of potential adverse metabolic and hemodynamic changes...
- Paradoxical carbon dioxide embolism during endoscopic thyroidectomy confirmed by transesophageal echocardiographySeong Hyop Kim
Department of Anesthesiology and Pain Medicine, Konkuk University School of Medicine, 1 Hwayang dong, Gwanggin Gu, Seoul 143 701, South Korea
J Anesth 24:774-7. 2010..Although endoscopic thyroidectomy using CO₂ gas insufflation appears to be superior to conventional open thyroidectomy in terms of cosmetic results, it may cause venous or ..
- A novel laparoscopic technique for removal of foreign bodies from the urinary bladder using carbon dioxide insufflationBala S Reddy
Department of Paediatric Surgery, Hull Royal Infirmary, Kingston upon Hull, United Kingdom
Surg Laparosc Endosc Percutan Tech 14:238-9. 2004....
- Cardiac function during intraperitoneal CO2 insufflation for aortic surgery: a transesophageal echocardiographic studyPascal Alfonsi
Department of Anesthesiology, and Intensive Care Unit, Ambroise Pare University Hospital, Assistance Publique Hopitaux de Paris, Boulogne, Cedex, France
Anesth Analg 102:1304-10. 2006..In conclusion, peritoneal CO2 insufflation in patients scheduled for laparoscopic aortic surgery could impair LV and RV systolic functions as a ..
- Increased expression of P-cadherin mRNA in the mouse peritoneum after carbon dioxide insufflationK Tahara
Department of Surgery I, Oita Medical University, 1 1 Idaigaoka, Hasama machi, Oita 879 5593, Japan
Surg Endosc 15:946-9. 2001..We investigated the expression of mRNA for adhesion molecules involved in cell-cell interactions, including ICAM-1, VCAM-1, CD44, E-cadherin, P-cadherin, and N-cadherin, after the induction of a CO(2) pneumoperitoneum in mice...
- Transcutaneous monitoring of partial pressure of carbon dioxide during endoscopic submucosal dissection of early colorectal neoplasia with carbon dioxide insufflation: a prospective studyTsuyoshi Kikuchi
Endoscopy Division, National Cancer Center Hospital, Chuo Ku, Tokyo, 104 0045, Japan
Surg Endosc 24:2231-5. 2010The authors have reported that carbon dioxide (CO(2)) insufflation is safe and effective for lengthy endoscopic submucosal dissection (ESD) with the patient under conscious sedation...
- Meta-analysis of the effect of warm humidified insufflation on pain after laparoscopyT Sammour
Department of Surgery, South Auckland Clinical School, University of Auckland, New Zealand
Br J Surg 95:950-6. 2008Studies on the use of warmed and humidified insufflation (WHI) in laparoscopic abdominal procedures to reduce pain have been inconclusive owing to small sample sizes.
- Hemodynamic responses to intrapleural insufflation with hemipulmonary collapseT Ohtsuka
Department of Cardiothoracic Surgery, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
Surg Endosc 15:1327-30. 2001The hemodynamic effects of carbon dioxide (CO2) insufflation with hemipulmonary collapse were studied in consecutive thoracoscopic harvests of the left or right internal mammary artery (IMA), which were used for video-assisted coronary ..
- Is carbon dioxide insufflation safe for laparoscopic surgery? A model to assess the effects of carbon dioxide on transitional-cell carcinoma growth, apoptosis, and necrosisBeng Jit Tan
Department of Urology, Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA
J Endourol 20:965-9. 2006To study the effects of carbon dioxide insufflation pressure and concentration on the adhesion, growth, apoptosis, and necrosis of transitional-cell carcinoma (TCC).
- Carbon dioxide embolism during laparoscopic cholecystectomy due to a patent paraumbilical veinPeter Mattei
Pediatric General, Thoracic and Fetal Surgery, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Pediatr Surg 42:570-2. 2007..cause is inadvertent injection of carbon dioxide into a large vein or solid organ during initial peritoneal insufflation. We describe a case of carbon dioxide embolism in a 13-year-old boy during an elective laparoscopic ..
- Carbon dioxide insufflation in colonoscopy: safe and effective in sedated patientsM Bretthauer
Dept of Gastroenterology, Rikshospitalet University Hospital, Oslo, Norway
Endoscopy 37:706-9. 2005Several studies have shown that insufflation of carbon dioxide (CO2) instead of air during colonoscopy can reduce postprocedural pain. However, CO2 insufflation might also lead to CO2 retention in the human body...
- Intraoperative evaluation of laparoscopic insufflation technique for quality control in the ORV R Jacobs
Department of Surgery, Fayette Medical Center, AL 35555, USA
JSLS 4:189-95. 2000..For intraoperative evaluation of insufflation techniques, a data acquisition model for quality control study of potential insufflation problems is necessary.
- Safety of carbon dioxide insufflation for upper gastrointestinal tract endoscopic treatment of patients under deep sedationSatoru Nonaka
Endoscopy Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
Surg Endosc 24:1638-45. 2010..This study aimed to investigate the safety of CO(2) insufflation used for esophageal and gastric endoscopic submucosal dissection (ESD) in patients under deep sedation.
- Minimizing postcolonoscopy abdominal pain by using CO(2) insufflation: a prospective, randomized, double blind, controlled trial evaluating a new commercially available CO(2) delivery systemKatica Sumanac
McMaster University Medical Center, Hamilton, Ontario, Canada
Gastrointest Endosc 56:190-4. 2002..A commercially available CO(2) delivery system has only recently become available. The effects of CO(2) and air insufflation on residual bowel gas and postprocedure pain were compared.
- Carbon dioxide insufflation for more comfortable endoscopic retrograde cholangiopancreatography: a randomized, controlled, double-blind trialM Bretthauer
Department of Medicine, Section of Gastroenterology, Rikshospitalet University Hospital, Oslo, Norway
Endoscopy 39:58-64. 2007The effect on abdominal pain of using carbon dioxide (CO2) for insufflation during endoscopic retrograde cholangiopancreatography (ERCP) has not been investigated...
- Nasopharyngeal oxygen insufflation following pre-oxygenation using the four deep breath techniqueS K Taha
Department of Anaesthesiology, American University of Beirut, Beirut, Lebanon
Anaesthesia 61:427-30. 2006This paper evaluates the effectiveness of nasopharyngeal oxygen insufflation following preoxygenation using the four deep breath technique within 30 s, on the onset of haemoglobin desaturation during the subsequent apnoea...
- CO2 abdominal insufflation pretreatment increases survival after a lipopolysaccharide-contaminated laparotomyJoseph M Fuentes
Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Gastrointest Surg 10:32-8. 2006..The presented studies were designed to determine whether treating animals with CO(2) abdominal insufflation before undergoing a lipopolysaccharide (LPS)-contaminated laparotomy would serve as "shock prophylaxis&..
- Mechanical properties of the human abdominal wall measured in vivo during insufflation for laparoscopic surgeryC Song
Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, Scotland
Surg Endosc 20:987-90. 2006Carbon dioxide insufflation of the peritoneal cavity for laparoscopic surgery offers a unique opportunity to measure some mechanical properties of the human abdominal wall that hitherto have been difficult to obtain.
- Cardiopulmonary, blood and peritoneal fluid alterations associated with abdominal insufflation of carbon dioxide in standing horsesF G Latimer
Equine Health Studies Program, Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, USA
Equine Vet J 35:283-90. 2003Abdominal insufflation is performed routinely during laparoscopy in horses to improve visualisation and facilitate instrument and visceral manipulations during surgery...
- Minimizing diaphragmatic injury during radiofrequency ablation: efficacy of intraabdominal carbon dioxide insufflationSteven S Raman
Department of Radiology, David Geffen School of Medicine at UCLA, BL 428 CHS Box 951721, Los Angeles, CA 90095 1721, USA
AJR Am J Roentgenol 183:197-200. 2004The purpose of our study was to determine whether intraperitoneal insufflation of carbon dioxide (CO(2)) reduces adjacent diaphragmatic injury.
- Double-blind, prospective, randomized study of warmed, humidified carbon dioxide insufflation vs standard carbon dioxide for patients undergoing laparoscopic cholecystectomyDavid R Farley
Departments of Surgery and Biostatistics, Mayo Clinic, Rochester, Minn 55905, USA
Arch Surg 139:739-43; discussion 743-4. 2004Patients undergoing warmed, humidified carbon dioxide (CO2) insufflation for laparoscopic cholecystectomy will (1) maintain a warmer intraoperative core temperature, (2) have their surgeon experience less fogging of the camera lens, and (..
- Primary microparticles and agglomerates of morphine for nasal insufflationPaola Russo
Department of Pharmacy, University of Parma, Parco Area delle Scienze 27 A, 43100 Parma, Italy
J Pharm Sci 95:2553-61. 2006..The agglomerates of morphine crystals mixed with mannitol/lecithin microparticles showed superior stability. However, the drug permeation through rabbit mucosa was slower than with spray-dried morphine microparticle agglomerates...
- Prospective randomized trial of heated humidified versus cold dry carbon dioxide insufflation during laparoscopic gastric bypassJ K Champion
Department of Surgery, Emory Dunwoody Medical Center, Atlanta, GA 30060, USA
Surg Obes Relat Dis 2:445-9; discussion 449-50. 2006The replacement of cold dry carbon dioxide with heated humidified gas for insufflation during complex laparoscopic procedures has been reported to decrease hypothermia and peritoneal cell desiccation, with a resultant decrease in ..
- Bedside transpyloric tube placement in the pediatric intensive care unit: a modified insufflation air techniquePaulo Sergio Lucas da Silva
Rua das Aroeiras, 30 ap 22 Bairro Jardim, Santo Andre, Sao Paulo, 09090 000, Brazil
Intensive Care Med 28:943-6. 2002To test air insufflation as an adjunct to placement of enteral feeding tubes and the effectiveness of using a smaller insufflation volume in pediatric patients.
- Supplementation of pre-oxygenation in morbidly obese patients using nasopharyngeal oxygen insufflationA S Baraka
Department of Anaesthesiology, American University of Beirut, Beirut, Lebanon
Anaesthesia 62:769-73. 2007..This study compares pre-oxygenation alone with pre-oxygenation followed by nasopharyngeal oxygen insufflation on the onset of desaturation occurring during the subsequent apnoea...
- Effect of manually assisted cough and mechanical insufflation on cough flow of normal subjects, patients with chronic obstructive pulmonary disease (COPD), and patients with respiratory muscle weaknessP Sivasothy
Respiratory Support and Sleep Centre, Papworth Hospital, Papworth Everard, Cambridge CB3 8RE, UK
Thorax 56:438-44. 2001It has been suggested that cough effectiveness can be improved by assisted techniques. The effects of manually assisted cough and mechanical insufflation on cough flow physiology are reported in this study.
- Effects of carbon dioxide insufflation for laparoscopic cholecystectomy on the respiratory systemP Pelosi
Department of Anaesthesia and Intensive Care, University of Milan, Ospedale Maggiore IRCCS, Italy
Anaesthesia 51:744-9. 1996..in total respiratory system, lung and chest wall mechanics, lung volume and gas-exchange during abdominal insufflation with carbon dioxide for laparoscopic cholecystectomy were studied...
- Endoscopic cross-trigonal ureteral reimplantation under carbon dioxide bladder insufflation: a novel techniqueC K Yeung
Division of Paediatric Surgery, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China
J Endourol 19:295-9. 2005..of endoscopic intravesical ureteral mobilization and cross-trigonal ureteral reimplantation under carbon dioxide insufflation of the bladder (pneumovesicum) for correcting primary vesicoureteral reflux (VUR) in infants and children.
- Colonic perforation at CT colonography in a patient without known colonic diseaseBrett M Young
Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
AJR Am J Roentgenol 186:119-21. 2006
- Initial trocar placement and abdominal insufflation in laparoscopic bariatric surgeryAtul K Madan
Minimally Invasive Surgery Section, Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Surg Res 148:210-3. 2008Initial trocar placement and abdominal insufflation in laparoscopic bariatric surgery can be challenging for the novice. One technique is the use of an optical viewing trocar without prior abdominal insufflation...
- New tools in ventilatory support: high frequency ventilation, nitric oxide, tracheal gas insufflation, non-invasive ventilationD Biarent
Pediatric and Neonatal Intensive Care Unit, Hopital Universitaire des Enfants, Reine Fabiola, Brussels, Belgium
Pediatr Pulmonol Suppl 18:178-81. 1999..Tracheal gas insufflation, in addition to conventional ventilation, by washing dead space during exhalation, improves gas exchange while ..
- Endoscopic thyroid resection using cutaneous elevation in lieu of insufflationH Kitano
Department of Otolaryngology, Head and Neck Surgery, Shiga University of Medical Science, Seta, Otsu, Shiga 520 2192, Japan
Surg Endosc 16:88-91. 2002..Laparoscopic surgery to resect cervical masses has gained increasing acceptance during the past decade. This report describes the authors' technique and experience using total video endoscopic surgery to resect thyroid masses...
- Acetazolamide reduces referred postoperative pain after laparoscopic surgery with carbon dioxide insufflationHarvey J Woehlck
Department of Anethesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
Anesthesiology 99:924-8. 2003..Acidification of the peritoneum by carbonic acid may be the major cause of pain from carbon dioxide insufflation. Carbonic anhydrase is an enzyme that increases the rate of carbonic acid formation from carbon dioxide...
- TRACHEAL GAS INSUFFLATION - PATIENT INTERFACE SYSTEMROBERT VIRAG; Fiscal Year: 2004The benefits of Tracheal Gas Insufflation (TGI) as an adjunct to mechanical ventilation are well known...
- Developing Physics-Based Virtual Simulation Technology for Natural Orifice TranslDANIEL BOUGERE JONES; Fiscal Year: 2013..is pumped into the body cavity (this is known as pneumoperitoneum and is achieved through a process known as insufflation) through the endoscope to increase work volume;(3) maintaining spatial orientation inside the body cavity;(4) ..
- Mechanisms and consequences of sleep disordered breathing in COPDCynthia D Brown; Fiscal Year: 2012..Individuals with COPD will undergo further evaluation with use of nocturnal nasal insufflation (NNI)...
- PROINFLAMMATORY ROLE OF URIC ACID IN LUNG DISEASE: NOVEL MODELS AND CLINICAL VALIRichard M Wright; Fiscal Year: 2013..ALI/ARDS will be induced using Th1 cytokine or LPS insufflation subsequent to XOR ablation...
- Comparative efficacy of water &indigo carmine vs water or air methodJoseph W Leung; Fiscal Year: 2013..In separate studies we reported that water infusion in lieu of air insufflation (water method) provided a significantly higher overall adenoma detection rate (ADR) and proximal diminutive ADR ..
- Pathogenesis and Outcomes of Sleep Disordered Breathing in COPDHartmut Schneider; Fiscal Year: 2013..In contrast, the PI recently established that nasal insufflation of room air (NI) effectively stabilizes breathing during sleep in patients with inspiratory flow limitation...
- Utilizing Ethyl Nitrate Gas in Laparoscopic SurgeryJames Reynolds; Fiscal Year: 2006..In addition, due to its plasma solubility, insufflation with CO2 will increase pCOz and decrease blood pH, actions that can produce respiratory acidosis, tachycardia, ..
- MBRS/SCORE Program at Fisk UniversityWARREN COLLINS; Fiscal Year: 2004..with specific emphasis on serotonin receptors; (2) Efforts to develop a mathematical model for tracheal gas insufflation; (3) Evaluate the performance of a series of porous glass ceramics on enzyme carriers, and to study the ..
- PULMONARY MASS AND HEAT TRANSPORTJames Grotberg; Fiscal Year: 2002..In the first project pulmonary gas transport during intra-tracheal insufflation (ITI), with or without external chest vibrations, will be studied to investigate ITI as a means of enhancing ..
- Human Cocaine DiscriminationCRAIG RUSH; Fiscal Year: 2006..Elucidating the role of dopamine in mediating the effects of cocaine may guide the development of pharmacological interventions for cocaine. ..
- LABORATORY ANALYSIS OF COCAINE ABSTINENCERICHARD FOLTIN; Fiscal Year: 2007..abstract_text> ..
- Preventing Cocaine Relapse: Developing PharmacotherapiesCRAIG RUSH; Fiscal Year: 2008..Reducing relapse to drug use is important because intravenous abuse of cocaine may be associated with increased risk of acquired immunodeficiency syndrome (A.I.D.S.). ..
- Mechanisms of Vitamin E Function Studied in ZebrafishMaret G Traber; Fiscal Year: 2010..the molecular targets altered by - tocopherol-deficiency in the zebrafish will provide a solid basis for understanding why humans require -tocopherol for reproduction as well as to maintain a healthy nervous system ..
- Agonist Replacement Therapy for Cocaine Dependence: Identifying Novel MedicationsCRAIG RUSH; Fiscal Year: 2009..Identifying novel agonist replacement therapies is important because clinicians may be reluctant to use d-amphetamine because of its abuse potential. ..
- Stimulant Abuse Pharmacotherapy: Novel AntipsychoticsCRAIG RUSH; Fiscal Year: 2009..The proposed research will provide initial scientific and clinical information regarding the use of aripiprazole as a pharmacotherapy for the treatment of methamphetamine dependence, and guide the design of future clinical trials. ..
- Reflexes and Supraesophageal Consequences of Reflux DiseaseBrendan J Canning; Fiscal Year: 2010..This research may also help identify novel therapeutic strategies for treating both GERD and chronic cough. ..
- Alpha-Tocopherol Modulation of Xenobiotic MetabolismMaret Traber; Fiscal Year: 2009..We believe that our findings may well have a significant impact on current self-medication practices of the millions of Americans currently taking prescription drugs and vitamin E supplements. ..
- IV COCAINE ABUSE TREATMENT: A LABORATORY MODELRICHARD FOLTIN; Fiscal Year: 2007..abstract_text> ..
- KININS AS MEDIATORS OF HUMAN REACTIONSBRENDAN CANNING; Fiscal Year: 2003..These rigorous studies will not only clarify the role of BK in airway diseases, but will also have broader relevance by providing new and important insights into how neural function is altered in asthma and rhinitis. ..
- Antioxidant Supplementation,Oxidative Stress & Enduranc*Maret Traber; Fiscal Year: 2002..Finally, the investigators plan to measure markers of inflammatory response, such as C-oxidants increase and vitamin E decreases these markers. ..
- GABA Agonists as Pharmacotherapies for Cocaine AbuseCRAIG RUSH; Fiscal Year: 2003..Finally, the proposed research will allow us to conduct retrospective analyses to determine the influence of individual differences (e.g., gender, other drug use) on the reinforcing and subjective effects of cocaine. ..
- ASSESSING ABUSE POTENTIAL IN HUMAN--CNS STIMULANTSCRAIG RUSH; Fiscal Year: 2004..abstract_text> ..
- Oral Care and Respiratory Pathogen ColonizationOzan Akca; Fiscal Year: 2004..Reducing respiratory pathogen colonization in the mouth could significantly reduce the morbidity and cost of VAP. ..
- AUTONOMIC REGULATION OF AIRWAY SMOOTH MUSCLE TONEBRENDAN CANNING; Fiscal Year: 2001..It is anticipated that this information will improve our understanding of the role of the autonomic innervation of the healthy and diseased lung. ..
- Oxidative Stress and Vitamin E RequirementsMaret Traber; Fiscal Year: 2005..These proposed studies will further our goal of understanding the role of vitamin E in the amelioration of oxidative damage in aging and in chronic diseases, such as heart disease, diabetes and cancer. ..
- Lung cancer chemoprevention and tocopheryl succinateRichard Wright; Fiscal Year: 2005..The overall goal of this work is that it may contribute to an eventual reduction in the incidence or severity of human lung cancers. ..
- Non-Surgical Device for Treatment of Middle Ear EffusionShlomo Silman; Fiscal Year: 2002..Although the custom-made device costs $325 including product liability, when commercially produced, it will cost about $5.00. ..
- AIRWAY PERFUSION ASSISTED LIQUID VENTILATORJames Parker; Fiscal Year: 2002..Other applications include continuous intrapulmonary administration of drugs and anesthetics and clearance of material from the lungs...
- Role of Estrogen in Exercise-Induced VEGF ExpressionPauline Entin; Fiscal Year: 2003..The results of this study will contribute to the assessment of the risk/benefit ratio for hormone replacement therapy, particularly in the context of those at risk for cardiovascular disease. ..
- TRPV4 Initiates Ventilator Induced Lung InjuryJames C Parker; Fiscal Year: 2010..and that lung PAR1 and PAR2 activation peptidesincrease lung vascular permeability in TRPV4+/+ mice ventilated with high airway pressures but not in TRPV4-/- mice, or either genotype ventilated with low airway pressures ..
- Peptides surface modification to prevent stent blockageJoseph Leung; Fiscal Year: 2006..The results may shed new lights in the prevention of chronic implanted medical device related infections and specifically in prolonging plastic stent patency. [unreadable] [unreadable]..
- Quantifying Left Ventricular Ejection EffectivenessMichael Pinsky; Fiscal Year: 2007..The ultimate goal of this proposal is to develop and validate an echocardiographic-based algorithm that quantifies LV ejection effectiveness by merging both power and synchrony of contraction into a common metric. ..
- Mechanical Injury to Lung EndotheliumJames Parker; Fiscal Year: 2001....