hemostatic techniques

Summary

Summary: Techniques for controlling bleeding.

Top Publications

  1. ncbi Complications associated with the arterial puncture closure device--Angio-Seal
    Alexander Kadner
    Swiss Cardiovascular Center, University Hospital, Freiburgerstrasse, Bern, Switzerland
    Vasc Endovascular Surg 42:225-7. 2008
  2. ncbi Early ambulation after diagnostic heart catheterization
    Bilal Boztosun
    Kosuyolu Heart and Research Centre, Cardiology Department, Istanbul, Turkey
    Angiology 58:743-6. 2007
  3. doi Reducing complications of femoral access
    Lowell Satler
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 71:524-5. 2008
  4. ncbi Closure of the femoral artery after cardiac catheterization: a comparison of Angio-Seal, StarClose, and manual compression
    J H H Deuling
    Department of Cardiology, Thorax Center, University Medical Center Groningen, University of Groningen, The Netherlands
    Catheter Cardiovasc Interv 71:518-23. 2008
  5. doi Common femoral artery stenosis after deployment of vascular clip closure device
    Larry A Osborn
    Division of Cardiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA
    Catheter Cardiovasc Interv 71:736-7. 2008
  6. ncbi Predictors of complications and learning curve using the Angio-Seal closure device following interventional and diagnostic catheterization
    B S Warren
    Department of Chemistry, Carleton College, Northfield, Minnesota, USA
    Catheter Cardiovasc Interv 48:162-6. 1999
  7. doi Efficacy of three topical hemostatic agents applied by medics in a lethal groin injury model
    Vance Y Sohn
    Department of Surgery and the Andersen Simulation Center, Madigan Army Medical Center, Tacoma, Washington 98431, USA
    J Surg Res 154:258-61. 2009
  8. ncbi Hemorrhage control research on today's battlefield: lessons applied
    John G McManus
    Brooke Army Medical Center, USA
    J Trauma 62:S14. 2007
  9. ncbi Safety and efficacy of a novel gel for vascular occlusion in off-pump surgery
    Munir Boodhwani
    Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Ann Thorac Surg 80:2333-7. 2005
  10. ncbi Arterial puncture closing devices compared with standard manual compression after cardiac catheterization: systematic review and meta-analysis
    Maria Koreny
    Department of Emergency Medicine, University of Vienna, Vienna General Hospital, Vienna, Austria
    JAMA 291:350-7. 2004

Research Grants

Detail Information

Publications190 found, 100 shown here

  1. ncbi Complications associated with the arterial puncture closure device--Angio-Seal
    Alexander Kadner
    Swiss Cardiovascular Center, University Hospital, Freiburgerstrasse, Bern, Switzerland
    Vasc Endovascular Surg 42:225-7. 2008
    ..Arterial puncture closure devices (APCD) are frequently used after cardiac catheterization. Here, the diagnosis and therapy of femoral artery complications after the use of the Angio-Seal APCD is reported...
  2. ncbi Early ambulation after diagnostic heart catheterization
    Bilal Boztosun
    Kosuyolu Heart and Research Centre, Cardiology Department, Istanbul, Turkey
    Angiology 58:743-6. 2007
    ..Early mobilization of selected patients undergoing diagnostic heart catheterization through the femoral artery via 6-Fr catheters is safe and associated with acceptable bleeding complication rates...
  3. doi Reducing complications of femoral access
    Lowell Satler
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 71:524-5. 2008
  4. ncbi Closure of the femoral artery after cardiac catheterization: a comparison of Angio-Seal, StarClose, and manual compression
    J H H Deuling
    Department of Cardiology, Thorax Center, University Medical Center Groningen, University of Groningen, The Netherlands
    Catheter Cardiovasc Interv 71:518-23. 2008
    ..To compare Angio-Seal (AS) and StarClose (SC) and manual compression (MC) on efficacy of hemostasis, complication rate, safety of early mobilization, and patient comfort...
  5. doi Common femoral artery stenosis after deployment of vascular clip closure device
    Larry A Osborn
    Division of Cardiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA
    Catheter Cardiovasc Interv 71:736-7. 2008
    ..We describe a case of symptomatic common femoral artery stenosis following use of a vascular clip closure device (StarClose). Operative repair was performed, with removal of the clip device and subsequent vein patch angioplasty...
  6. ncbi Predictors of complications and learning curve using the Angio-Seal closure device following interventional and diagnostic catheterization
    B S Warren
    Department of Chemistry, Carleton College, Northfield, Minnesota, USA
    Catheter Cardiovasc Interv 48:162-6. 1999
    ..009) and failure to deploy was independent of sheath size used. Angio-Seal can be used with reasonable safety and efficacy immediately after diagnostic and interventional procedures. Cathet. Cardiovasc. Intervent. 48:162-166, 1999...
  7. doi Efficacy of three topical hemostatic agents applied by medics in a lethal groin injury model
    Vance Y Sohn
    Department of Surgery and the Andersen Simulation Center, Madigan Army Medical Center, Tacoma, Washington 98431, USA
    J Surg Res 154:258-61. 2009
    ..We sought to determine the efficacy of three chitosan based hemostatic agents in a lethal groin injury model when applied by combat medic first responders...
  8. ncbi Hemorrhage control research on today's battlefield: lessons applied
    John G McManus
    Brooke Army Medical Center, USA
    J Trauma 62:S14. 2007
  9. ncbi Safety and efficacy of a novel gel for vascular occlusion in off-pump surgery
    Munir Boodhwani
    Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Ann Thorac Surg 80:2333-7. 2005
    ..We evaluated a novel gel with reverse thermosensitive properties for internal vessel occlusion during off-pump coronary artery bypass surgery...
  10. ncbi Arterial puncture closing devices compared with standard manual compression after cardiac catheterization: systematic review and meta-analysis
    Maria Koreny
    Department of Emergency Medicine, University of Vienna, Vienna General Hospital, Vienna, Austria
    JAMA 291:350-7. 2004
    ..Arterial puncture closing devices (APCDs) were developed to replace standard compression at the puncture site and to shorten bed rest following percutaneous coronary intervention...
  11. pmc Efficacy of femoral vascular closure devices in patients treated with anticoagulant, abciximab or thrombolytics during percutaneous endovascular procedures
    Ha Young Kim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Radiol 7:35-40. 2006
    ....
  12. ncbi Femoral artery stenosis following percutaneous closure using a starclose closure device
    Clare Louise Bent
    Department of Diagnostic Imaging, Barts and The London NHS Trust, Whitechapel, London, E1 1BB, UK
    Cardiovasc Intervent Radiol 31:814-6. 2008
    ..A Starclose femoral artery closure device was used to achieve hemostasis with subsequent femoral artery stenosis...
  13. ncbi Vascular closure devices: the second decade
    Harold L Dauerman
    Division of Cardiology, University of Vermont College of Medicine, Burlington, Vermont 05401, USA
    J Am Coll Cardiol 50:1617-26. 2007
    ..Challenges in the second decade of VCD experience will include performing definitive randomized trials, evaluating outcomes in higher-risk patients, and developing more ideal closure devices...
  14. ncbi Efficacy and safety of the perclose closer s device after neurointerventional procedures: prospective study and literature review
    Kamran Khaghany
    Michigan State University College of Human Medicine, Kalamazoo Center for Medical Studies, 49048, USA
    AJNR Am J Neuroradiol 26:1420-4. 2005
    ....
  15. ncbi Liver hemostasis with high-intensity ultrasound: repair and healing
    Shahram Vaezy
    Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, Seattle, WA 98105, USA
    J Ultrasound Med 23:217-25. 2004
    ..This study investigated long-term hemostasis and tissue repair after high-intensity focused ultrasound treatment in liver...
  16. ncbi Abdominal insufflation for control of bleeding after severe splenic injury
    George C Velmahos
    Division of Trauma, Emergency Surgery, and Surgical Critical Care, Department of Surgery, The Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Trauma 63:285-8; discussion 288-90. 2007
    ..This model represents a clinically relevant scenario of continuous bleeding, which does not kill the patient immediately but may ultimately result in death if not managed early...
  17. ncbi Percutaneous transluminal dilatation of inadvertent partial or complete occlusion of the femoral artery caused by Angio-Seal deployment for puncture site closure after cardiac catheterization
    Martin Brueck
    Department of Cardiology, Interventional Radiology, Clinic of Wetzlar, Wetzlar, Germany
    J Invasive Cardiol 22:353-7. 2010
    ..PTA appears to be a safe and effective method of treatment, avoiding surgical removal of the plug...
  18. ncbi Host-guest composites for induced hemostasis and therapeutic healing in traumatic injuries
    Todd A Ostomel
    Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, California, 93106, USA
    J Thromb Thrombolysis 22:55-67. 2006
    ..Five ion exchanged derivatives of the parent HA were prepared and characterized with regard to their material and thermal properties, in vitro hemostatic efficacy, and antibacterial activity...
  19. ncbi Vascular complications after percutaneous coronary interventions following hemostasis with manual compression versus arteriotomy closure devices
    G Dangas
    Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York, New York, USA
    J Am Coll Cardiol 38:638-41. 2001
    ..5 vs. 1.5%, p = 0.03). CONCLUSIONS: In this early experience with ACD after PCI, their use was associated with higher vascular complication rates than hemostasis with manual compression...
  20. ncbi Advanced hemostatic dressing development program: animal model selection criteria and results of a study of nine hemostatic dressings in a model of severe large venous hemorrhage and hepatic injury in Swine
    Anthony E Pusateri
    US Army Institute of Surgical Research, Fort Sam Houston, TX 78234 6315, USA
    J Trauma 55:518-26. 2003
    ..A systematic approach to the study of dressings is described. We studied the effects of nine hemostatic dressings on blood loss using a model of severe venous hemorrhage and hepatic injury in swine...
  21. ncbi Angioseal versus manual compression for haemostasis following peripheral vascular diagnostic and interventional procedures--a randomized controlled trial
    S S Upponi
    Department of Clinical Radiology, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DZ, United Kingdom
    Eur J Radiol 61:332-4. 2007
    ..0 min in the angioseal group (t-test p<0.0001). In conclusion, no significant differences in complications were found between manual compression and angioseal. However, there was a significant difference in time to haemostasis...
  22. doi Direct retroperitoneal pelvic packing versus pelvic angiography: A comparison of two management protocols for haemodynamically unstable pelvic fractures
    Patrick M Osborn
    Department of Orthopaedic Surgery, Denver Health Medical Center, University of Colorado School of Medicine, 777 Bannock Street, Denver, CO 80204, USA
    Injury 40:54-60. 2009
    ..To evaluate the outcomes of haemodynamically unstable cases of pelvic ring injury treated with a protocol focused on either direct retroperitoneal pelvic packing or early pelvic angiography and embolisation...
  23. ncbi The coagulopathy of trauma versus disseminated intravascular coagulation
    John R Hess
    Department of Pathology, University of Maryland Medical Center, Baltimore, 21201, USA
    J Trauma 60:S12-9. 2006
    ..The coagulopathy of trauma should be anticipated in massive transfusion situations. Early treatment with plasma can delay its onset. The underlying mechanisms should be confirmed with laboratory testing...
  24. ncbi Local vascular complications after use of the hemostatic puncture closure device Angio-Seal
    C Kirchhof
    Department of Medicine, Park Krankenhaus Leipzig Südost GmbH, Leipzig, Germany
    Vasa 31:101-6. 2002
    ..Here we report about the diagnosis and therapy of femoral artery complications after use of the closure device Angio-Seal, consisting of an intraarterial anchor and extravascular collagen plug...
  25. doi Posterior wall capture and resultant common femoral occlusion complicating StarClose access closure
    Patrick A Stone
    West Virginia University School of Medicine, Charleston Division, Charleston, WV, USA
    J Vasc Surg 48:469-71. 2008
    ..We provide objective observations from the rescue surgical intervention and discuss potential mechanisms of device failure...
  26. ncbi Acute arterial occlusion after deployment of the Angio-Seal closure device: is it as uncommon as we think?
    H J J van der Steeg
    Department of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur J Vasc Endovasc Surg 38:715-7. 2009
    ..Surgical intervention was necessary in all cases. Acute arterial occlusion after deployment of the Angio-Seal in patients with peripheral arterial disease might be less uncommon than the literature suggests...
  27. ncbi Training with the compactEASIE biologic endoscopy simulator significantly improves hemostatic technical skill of gastroenterology fellows: a randomized controlled comparison with clinical endoscopy training alone
    Juergen Hochberger
    Gastrointest Endosc 61:204-15. 2005
    ..study, therefore, was conducted to compare the effects of intensive 7-month, hands-on training in hemostatic techniques by using the compactEASIE model (in addition to clinical endoscopic training) vs...
  28. ncbi Angio-Seal use in patients with peripheral arterial disease (ASPIRE)
    Reinhold Katzenschlager
    Department of Angiology, Hanusch Hospital, Vienna, Austria
    Angiology 60:536-8. 2009
    ..To investigate the incidence of complications after the use of an arterial closure device (Angio-Seal) in patients with peripheral arterial disease...
  29. ncbi Recent experiences with a multidisciplinary approach to complex hepatic trauma
    Shawn MacKenzie
    Department of General Surgery, University of Calgary, Calgary, Alta, Canada T2N 2T9
    Injury 35:869-77. 2004
    ..This is often followed by hepatic arteriography with angioembolization, resuscitation, and early re-exploration under more optimal physiological conditions. This study describes the initial outcomes of this approach...
  30. ncbi Hemodynamic efficacy of the new resolution clip device in comparison with high-volume injection therapy in spurting bleeding: a prospective experimental trial using the compactEASIE simulator
    J Maiss
    Deparment of Medicine I, University of Erlangen Nuremberg, Erlangen, Germany
    Endoscopy 38:808-12. 2006
    ..However, hemoclips have not previously been compared with injection therapy in an experimental setting using objective parameters...
  31. ncbi Consensus recommendations for managing patients with nonvariceal upper gastrointestinal bleeding
    Alan Barkun
    McGill University, Montreal, Quebec, Canada
    Ann Intern Med 139:843-57. 2003
    ..The management of patients with acute nonvariceal upper gastrointestinal bleeding has evolved substantially over the past 10 years amid a paucity of published consensus guidelines...
  32. ncbi Efficacy and complications of Angioseal in antegrade puncture
    Kausik Mukhopadhyay
    Derriford Hospital, Plymouth, UK
    Eur J Radiol 56:409-12. 2005
    ..Although arterial closure devices are in use for over a decade, there have been no specific study to assess the use of the same in antegrade puncture...
  33. ncbi Damage control orthopaedics in unstable pelvic ring injuries
    P V Giannoudis
    Departments of Trauma and Orthopaedic Surgery, St James s University Hospital, University of Leeds, Leeds LS9 7TF, UK
    Injury 35:671-7. 2004
    ....
  34. ncbi Guidelines for the use of recombinant activated factor VII (rFVIIa) in uncontrolled bleeding: a report by the Israeli Multidisciplinary rFVIIa Task Force
    U Martinowitz
    National Hemophilia Center, Chaim Sheba Medical Center, Tel Hashomer and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Thromb Haemost 3:640-8. 2005
    ..While evidence-based guidelines exist for rFVIIa treatment in hemophilia, none are available for its off-label use...
  35. ncbi Extraperitoneal pelvic packing: a salvage procedure to control massive traumatic pelvic hemorrhage
    Anna Tötterman
    Orthopedic Centre, Ulleval University Hospital, Oslo, Norway
    J Trauma 62:843-52. 2007
    ..To describe the method of extraperitoneal pelvic packing (EPP), and to assess the impact of EPP on outcome in severely hemodynamically unstable patients after blunt pelvic trauma...
  36. ncbi Packing for control of hemorrhage in major liver trauma
    A J Nicol
    Department of Surgery, Trauma Unit, Ward C14, Groote Schuur Hospital, Anzio Road, Observatory, Cape Town, 7925, South Africa
    World J Surg 31:569-74. 2007
    ..The aim of the present study was to determine the optimum timing of pack removal and to assess whether the total duration of packing increases the incidence of these complications...
  37. pmc Clinical review: initial management of blunt pelvic trauma patients with haemodynamic instability
    Thomas Geeraerts
    département d anesthésie réanimation chirurgicale, Centre Hospitalier Universitaire de Bicetre, Assistance Publique Hopitaux de Paris, Univ Paris Sud, Le Kremlin Bicetre, France
    Crit Care 11:204. 2007
    ..A decision making algorithm is proposed for the treatment of trauma patients with pelvic fracture that takes haemodynamic status and associated lesions into account...
  38. pmc Management of bleeding following major trauma: a European guideline
    Donat R Spahn
    Department of Anesthesiology, University Hospital Zurich, Zurich, Switzerland
    Crit Care 11:R17. 2007
    ..Evidence-based recommendations can be made with respect to many aspects of the acute management of the bleeding trauma patient, which when implemented may lead to improved patient outcomes...
  39. ncbi Retroperitoneal packing as a resuscitation technique for hemodynamically unstable patients with pelvic fractures: report of two representative cases and a description of technique
    Wade R Smith
    Department of Orthopaedic Surgery, Denver Health Medical Center, University of Colorado School of Medicine, Denver, Colorado 80204, USA
    J Trauma 59:1510-4. 2005
  40. ncbi Damage control management of experimental grade 5 renal injuries: further evaluation of FloSeal gelatin matrix
    Nathan F Pursifull
    Urology Service, Brooke Army Medical Center, Fort Sam Houston, Texas 78324, USA
    J Trauma 60:346-50. 2006
    ..We developed a porcine grade 5 renal laceration damage control model to evaluate the hemostatic efficacy of FloSeal gelatin matrix (Baxter Healthcare, Corp., Deerfield, Ill)...
  41. ncbi Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerations
    David S Kauvar
    United States Army Institute of Surgical Research, Fort Sam Houston, San Antonio, Texas 78234, USA
    J Trauma 60:S3-11. 2006
    ..Improvements in early hemorrhage control and resuscitation and the prevention and aggressive treatment of coagulopathy appear to have the greatest potential to improve outcomes in severely injured trauma patients...
  42. ncbi Guidelines on the management of massive blood loss
    D Stainsby
    National Blood Service, UK
    Br J Haematol 135:634-41. 2006
  43. ncbi Modified rapid deployment hemostat bandage terminates bleeding in coagulopathic patients with severe visceral injuries
    David R King
    DeWitt Daughtry Family Department of Surgery, Division of Trauma, Trauma and Surgical Critical Care Research Institute, University of Miami School of Medicine, Miami, Florida 33136, USA
    J Trauma 57:756-9. 2004
    ..The purpose of this study was to evaluate the MRDH in coagulopathic trauma patients undergoing abbreviated laparotomy...
  44. ncbi Efficacy and safety of the angioseal vascular closure device post antegrade puncture
    S Looby
    Department of Radiology, Beaumont Hospital, Dublin 9, Ireland
    Cardiovasc Intervent Radiol 31:558-62. 2008
    ..Nine of these patients had undergone ipsilateral Angioseal deployment in the previous 3 months. We conclude that the Angioseal vascular closure device is a safe and efficient means of achieving hemostasis post antegrade puncture...
  45. doi Massive hemorrhage in facial fracture patients: definition, incidence, and management
    Nicola R Dean
    Flinders Medical Center, Flinders University, Adelaide, Australia
    Plast Reconstr Surg 123:680-90. 2009
    ..Significant hemorrhage from fractures of the midface is a recognized phenomenon, but because it is an uncommon occurrence, there is little in the literature to guide management of these patients...
  46. doi The effectiveness of a damage control resuscitation strategy for vascular injury in a combat support hospital: results of a case control study
    Charles J Fox
    Department of Surgery, Walter Reed Army Medical Center, Washington, DC 20307, USA
    J Trauma 64:S99-106; discussion S106-7. 2008
    ..The objective of this report is to establish the use and effectiveness of a damage control resuscitation (DCR) strategy in the setting of wartime vascular injury...
  47. ncbi High intensity focused ultrasound: a method of hemostasis
    S Vaezy
    Department of Bioengineering, Box 357962, University of Washington, Seattle, WA 98195, USA
    Echocardiography 18:309-15. 2001
    ..Image-guided acoustic hemostasis may provide a valuable method of hemostasis in surgical and prehospital settings with applications in trauma and elective surgery...
  48. ncbi Microbubble-enhanced hemorrhage control using high intensity focused ultrasound
    Vesna Zderic
    Department of Bioengineering, University of Washington, Seattle, WA 98195, USA
    Ultrasonics 45:113-20. 2006
    ..Our results suggest potential utility of UCA for increasing efficiency of HIFU-induced hemostasis of solid organ injuries...
  49. ncbi Major postpartum hemorrhage: survey of maternity units in the United Kingdom
    Hatem A Mousa
    University Department of Obstetrics and Gynecology, Liverpool Women s Hospital, UK
    Acta Obstet Gynecol Scand 81:727-30. 2002
    ..To determine current clinical practice among different maternity units in the United Kingdom for the management of major postpartum hemorrhage...
  50. ncbi Vascular closure devices in patients treated with anticoagulation and IIb/IIIa receptor inhibitors during percutaneous revascularization
    Robert J Applegate
    Section of Cardiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1045, USA
    J Am Coll Cardiol 40:78-83. 2002
    ..The study assessed clinical outcomes of closure device use following percutaneous coronary revascularization using current standards of anticoagulation and antiplatelet therapy...
  51. ncbi Usefulness of collagen plugging with VasoSeal after PTCA as compared to manual compression with identical sheath dwell times
    S Silber
    Dr Muller Hospital, Munich, Germany
    Cathet Cardiovasc Diagn 43:421-7. 1998
    ..Although the incidence of medium or large hematoma was low, the trend towards a decreased risk of smaller hematomas seemed to be counterbalanced by an increased risk of larger hematomas...
  52. ncbi A prospective randomized trial comparing the safety and efficacy of three commercially available closure devices (Angioseal, Vasoseal and Duett)
    Lampros K Michalis
    Cardiac Department, University Hospital of Ioannina, Ioannina, Greece
    Cardiovasc Intervent Radiol 25:423-9. 2002
    ..We compared the safety and efficacy of three closure devices (Angioseal, Vasoseal and Duett) used to close arterial puncture sites in patients who underwent coronary percutaneous procedures...
  53. ncbi Femoral arterial puncture management after percutaneous coronary procedures: a comparison of clinical outcomes and patient satisfaction between manual compression and two different vascular closure devices
    D C Duffin
    Division of Cardiology, LDS Hospital, 8th Avenue and C Street, Salt Lake City, Utah 84143, USA
    J Invasive Cardiol 13:354-62. 2001
    ..Additionally, Angio-Seal performed better than Perclose in exhibiting a superior 30-day patient satisfaction and patient assessment of wound healing with less discomfort...
  54. ncbi Interruption of blood flow during compression and radial artery occlusion after transradial catheterization
    Marcelo Sanmartin
    Unidad de Cardiologia Intervencionista, Medtec, Hospital Meixoeiro, Vigo, Spain
    Catheter Cardiovasc Interv 70:185-9. 2007
    ..To analyze the possible relationship between compression after transradial catheterization and radial artery occlusion...
  55. ncbi Initial experience with the Cardiva Boomerang vascular closure device in diagnostic catheterization
    Brendan J Doyle
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
    Catheter Cardiovasc Interv 69:203-8. 2007
    ..The authors studied the safety and efficacy of the Cardiva Boomerang vascular closure device in patients undergoing diagnostic cardiac catheterization...
  56. ncbi Randomized controlled trial of topical hemostasis pad use for achieving vascular hemostasis following percutaneous coronary intervention
    Nhan Nguyen
    Division of Cardiology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Catheter Cardiovasc Interv 69:801-7. 2007
    ..We conducted a randomized trial to determine the efficacy of two topical hemostasis pads in promoting vascular hemostasis following PCI, and to assess the appropriate level of anticoagulation for sheath removal...
  57. ncbi Contemporary management of acute lower extremity ischemia following percutaneous coronary and cardiac interventional procedures using femoral access--a case series and discussion
    Andrew J Klein
    University of Colorado Health Sciences at Denver, Denver, Colorado 80262, USA
    Catheter Cardiovasc Interv 70:129-37. 2007
    ....
  58. ncbi Prevention of radial artery occlusion-patent hemostasis evaluation trial (PROPHET study): a randomized comparison of traditional versus patency documented hemostasis after transradial catheterization
    Samir Pancholy
    Department of Cardiology, Mercy Hospital and Community Medical Center, Scranton, PA, USA
    Catheter Cardiovasc Interv 72:335-40. 2008
    ..The objective of this study was to evaluate the efficacy of hemostasis with patency in avoiding radial artery occlusion after transradial catheterization...
  59. ncbi Ischemic complications of percutaneous femoral artery catheterization
    Paul M Schumacher
    Department of Vascular Surgery, Vanderbilt University Medical Center, Nashville, TN 37232 2735, USA
    Ann Vasc Surg 21:704-12. 2007
    ..Vascular surgeons should anticipate a new pattern of injury following femoral artery catheterization, one that often requires complex arterial reconstruction...
  60. doi The matter at hand
    Samuel Butman
    Catheter Cardiovasc Interv 72:341-2. 2008
  61. ncbi The StarClose Vascular Closure System: interventional results from the CLIP study
    J B Hermiller
    St Vincent s Hospital, Indianapolis, Indiana, USA
    Catheter Cardiovasc Interv 68:677-83. 2006
    ..The Clip CLosure In Percutaneous Procedures study was initiated to study the safety and efficacy of the StarClose device in subjects undergoing diagnostic and interventional catheterization procedures...
  62. ncbi Moving in the right direction
    George W Vetrovec
    Catheter Cardiovasc Interv 70:634. 2007
  63. ncbi Risk of local adverse events by gender following cardiac catheterization
    Dale R Tavris
    Food and Drug Administration, Center for Devices and Radiological Health Epidemiology Branch Gallauresi Beverly, MA, USA
    Pharmacoepidemiol Drug Saf 16:125-31. 2007
    ..To assess the reason for the relative high risk of local complications for women following cardiac catheterization by evaluating the associations between gender, sheath size, and local adverse outcomes following cardiac catheterization...
  64. ncbi Stent-grafts in the management of hemorrhagic complications related to hemostatic closure devices: report of two cases
    Daniel Giansante Abud
    Department of Interventional Neuroradiology, Fondation Rothschild, 25 29 rue Manin, 75940 Paris Cedex 19, France
    Cardiovasc Intervent Radiol 30:104-7. 2007
    ..The lesions were managed with stent-grafts. The use of stent-grafts proved to be efficient in the management of these life-threatening hemorrhagic complications following the use of the Angio-Seal hemostatic closure device...
  65. ncbi Acute claudication caused by Angio-Seal closure devices: a report of four cases
    E Mattens
    Department of Surgery, Diaconessenhuis, Meppel, The Netherlands
    Acta Chir Belg 108:247-50. 2008
    ..The occurrence of few serious complications can outweigh the relative small benefits these devices offer...
  66. ncbi Arterial puncture closure using a clip device after transpopliteal retrograde approach for recanalization of the superficial femoral artery
    Elias Noory
    Department of Angiology, Herz Zentrum Bad Krozingen, Germany
    J Endovasc Ther 15:310-4. 2008
    ..To report the safety and efficacy of a clip device to close retrograde popliteal artery puncture sites used in recanalization of the superficial femoral artery (SFA)...
  67. ncbi [Vascular approaches and closure devices for percutaneous coronary intervention]
    J Monsegu
    Service de cardiologie, Hopital du Val de Grace, 74, boulevard de Port Royal, 75230 Paris Cedex 05, France
    Ann Cardiol Angeiol (Paris) 56:263-8. 2007
    ..Since the emergent transradial approach in France has led to a dramatic reduction in local vascular complications, we also discuss the remaining place of femoral approach and the usefulness of femoral percutaneous closure devices...
  68. ncbi The experience with the Epiclose-T vascular access closure device: a human study
    Hurkan Kursaklioglu
    Department of Cardiology, Gulhane Military Medical Academy, Ankara, Turkey
    Anadolu Kardiyol Derg 8:38-42. 2008
    ..We assessed prospectively the initial safety and efficacy of the Epiclose-T after diagnostic cardiac catheterization, and evaluated patient comfort...
  69. ncbi The safety and efficacy of an extravascular, water-soluble sealant for vascular closure: initial clinical results for Mynx
    D Scheinert
    Department of Angiology, Heart Center, University of Leipzig, Leipzig, Germany
    Catheter Cardiovasc Interv 70:627-33. 2007
    ..The purpose of this study was to evaluate the hemostatic efficacy and safety of the Mynx extravascular sealant for femoral artery closure...
  70. ncbi Treatment of iatrogenic femoral pseudoaneurysm by ultrasound-guided compression therapy and thrombin injection
    Mark Luedde
    Department of Cardiology, University of Heidelberg, Germany heidelberg de
    Angiology 58:435-9. 2007
    ..Patients with a pseudoaneurysm with a wide "neck" should be treated surgically, because the risk of an arterial occlusion following thrombin injection cannot be excluded...
  71. ncbi Angio-seal in antegrade endovascular interventions: technical success and complications in a 55-patient series
    Baljendra Kapoor
    Vascular and Interventional Radiology, The University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    J Endovasc Ther 14:382-6. 2007
    ..To assess the technical success and complications of Angio-Seal vascular closure device in antegrade common femoral artery (CFA) punctures...
  72. ncbi Midterm outcomes of femoral arteries after percutaneous endovascular aortic repair using the Preclose technique
    W Anthony Lee
    University of Florida, Division of Vascular Surgery and Endovascular Therapy, Gainesville, FL 32610 0286, USA
    J Vasc Surg 47:919-23. 2008
    ..The purpose of this study is to examine the late outcomes of those femoral arteries repaired in this manner...
  73. ncbi StarClose vascular closure device: prospective study on 222 deployments in an interventional radiology practice
    Atique Imam
    Department of Radiology, John Radcliffe Hospital, Headley Way, OX3 9DU, Headington, Oxford, UK
    Cardiovasc Intervent Radiol 30:738-42. 2007
    ..Deployments were successful in 96% achieving immediate hemostasis. Mean deployment time was 48 s. There were no major complications. The StarClose device was found to have a high technical and clinical efficacy...
  74. doi The road to perfect closure--still unpaved
    Zoltan G Turi
    Catheter Cardiovasc Interv 71:738-9. 2008
  75. ncbi Trapping of vascular clip closure device in previously accessed femoral puncture site
    Steven J Fowler
    Division of Cardiology, The University of California, Irvine Medical Center, Orange, California 92868 4080, USA
    Catheter Cardiovasc Interv 70:62-4. 2007
  76. doi Cutaneous migration of the StarClose device
    Markus Aschwanden
    Department of Angiology, University Hospital Basel, Basel, Switzerland
    Catheter Cardiovasc Interv 71:744-6. 2008
    ..We postulate focal inflammatory vascular wall changes as the predisposing factor in this patient with giant cell arteritis...
  77. ncbi Comparison of arterial closure devices in antegrade and retrograde punctures
    Albert Ho Yuen Chiu
    Department of Radiology, Sir Charles Gairdner Hospital, Perth, Australia
    J Endovasc Ther 15:315-21. 2008
    ..To compare the efficacy, primary failure rates, and complications for the Angio-Seal and Perclose closure devices in antegrade and retrograde common femoral artery (CFA) punctures during peripheral angioplasty procedures...
  78. ncbi Arterial closure devices. A review
    J B Madigan
    Radiology Department, St Georges Hospital, London, UK
    J Cardiovasc Surg (Torino) 48:607-24. 2007
    ..In spite of the wide range of devices currently available there remains room for improvement...
  79. ncbi Use of the profunda femoris to facilitate closure of an antegrade puncture with the StarClose device after proximal SFA angioplasty
    Susan Yeung-Ngok-Kao
    Interventional Radiology and Northern Vascular Center, Radiology Department, Freeman Hospital, Newcastle upon Tyne, UK
    J Endovasc Ther 13:522-6. 2006
    ..To report a novel technique for safely closing antegrade common femoral artery (CFA) punctures using the StarClose device after proximal superficial femoral artery (SFA) angioplasty...
  80. ncbi Safety of heparin reversal with protamin and immediate sheath removal after coronary angioplasty
    F Lohne
    Faculty of Medicine, Department of Cardiovascular Radiology, Ulleval University Hospital, Oslo, Norway
    Acta Radiol 45:171-5. 2004
    ..To study the safety of giving protamin after coronary angioplasty to reverse heparin for immediate removal of the femoral sheath...
  81. ncbi Hemorrhage control in arteries using high-intensity focused ultrasound: a survival study
    Vesna Zderic
    Applied Physics Laboratory, Center for Industrial and Medical Ultrasound, University of Washington, 1013 NE 40th Street, Seattle, WA 98105, USA
    Ultrasonics 44:46-53. 2006
    ..The results show that HIFU can produce effective and long-term (up to 60 days) hemostasis of punctured femoral arteries while preserving normal blood flow and vessel wall structure in the majority of vessels...
  82. ncbi [Treatment of pseudoaneurysms after vascular interventions]
    Ragnhild Marie Undseth
    Hjerte og karradiologisk avdeling, Ulleval universitetssykehus, 0407 Oslo
    Tidsskr Nor Laegeforen 124:1384-6. 2004
    ..Until recently, ultrasound-guided compression was the preferred method of treatment, in a few cases surgery. A newer method with ultrasound-guided injection of thrombin has been shown to be effective...
  83. ncbi Application of the poly-N-acetyl glucosamine-derived rapid deployment hemostat trauma dressing in severe/lethal Swine hemorrhage trauma models
    Raymond J Connolly
    Department of Surgery, New England Medical Center, Boston, Massachusetts 02111, USA
    J Trauma 57:S26-8. 2004
    ..The Rapid Deployment Hemostat (RDH) Bandage was developed for the rapid control of bleeding caused by trauma...
  84. ncbi Risk of local adverse events following cardiac catheterization by hemostasis device use and gender
    Dale R Tavris
    Food and Drug Administration, Center for Devices and Radiological Health, Division of Postmarket Surveilance, USA
    J Invasive Cardiol 16:459-64. 2004
    ..This study assessed the relative risk of serious complications following the use of the two main types of hemostasis devices (as compared with manual compression), and assessed the relative rates of these complications by gender...
  85. ncbi The use of closure devices
    Steven G Katz
    Keck USC School of Medicine, 1975 Zonal Ave, Los Angeles, CA 90033, USA
    Surg Clin North Am 84:1267-80, vi. 2004
    ..Their use may be of particular benefit inpatients that are anticoagulated. We believe that their use should be strongly considered in all patients following femoral artery catheterization...
  86. ncbi Relative risks of reported serious injury and death associated with hemostasis devices by gender
    Dale R Tavris
    Epidemiology Branch, Division of Postmarket Surveillance, Office of Surveillance and Biometrics, Center for Devices and Radiological Health, Food and Drug Administration, 1350 Piccard Drive, HFZ 541, Rockville, MD 20850, USA
    Pharmacoepidemiol Drug Saf 12:237-41. 2003
    ..To assess relative risks by gender of reported serious injuries and deaths associated with the use of hemostasis devices, stratified by year of report, type of injury, and type of device...
  87. ncbi Case-controlled comparison of a percutaneous collagen arteriotomy closure device versus manual compression after liver chemoembolization
    Kelvin Hong
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, 600 North Wolfe Street, Blalock 545, Baltimore, Maryland 21287, USA
    J Vasc Interv Radiol 16:339-45. 2005
    ....
  88. ncbi Predictors of complications associated with closure devices after transfemoral percutaneous coronary procedures
    Jenny B Hamner
    Auburn University School of Nursing, Auburn, Ala, USA
    Crit Care Nurse 25:30-2, 34-7. 2005
  89. ncbi [Local lysis with alteplase for the treatment of acute embolic leg ischemia following the use of the duett closure device: preliminary results]
    K Schurmann
    Klinik für Radiologische Diagnostik des Universitätsklinikums der RWTH Aachen
    Rofo 176:574-9. 2004
    ..To analyze retrospectively the result of the alteplase lysis therapy of embolic complications following the use of the Duett closure device...
  90. ncbi The safety and efficacy of angioseal in therapeutic endovascular interventions
    M Aksoy
    Department of General Surgery, Medical Faculty of Istanbul, Istanbul, Turkey
    Eur J Vasc Endovasc Surg 32:90-3. 2006
    ..The aim of this study was to evaluate the safety and efficacy of the closure device Angioseal...
  91. pmc To plug or not to plug?
    Joseph Varon
    The University of Texas Health Science Center, St Luke s Episcopal Hospital, Houston, Texas, USA
    Crit Care 8:87-8. 2004
    ..Further, well designed studies are necessary to document the comparative effects of these devices versus manual compression...
  92. ncbi The management of peripheral vascular complications associated with the use of percutaneous suture-mediated closure devices
    L R Sprouse
    University of Tennessee College of Medicine, Chattanooga Unit, Department of Surgery, USA
    J Vasc Surg 33:688-93. 2001
    ....
  93. ncbi Clinical evaluation of SyvekPatch in patients undergoing interventional, EPS and diagnostic cardiac catheterization procedures
    R G Nader
    Mt Sinai Medical Center and Miami Heart Institute, Miami Beach, FL, USA
    J Invasive Cardiol 14:305-7. 2002
    ..A clinical evaluation was designed to determine the efficacy and safety of this vascular closure device in 1,000 consecutive patients after routine diagnostic and interventional procedures...
  94. ncbi Systematic use of a collagen-based vascular closure device immediately after cardiac catheterization procedures in 1,317 consecutive patients
    Holger Eggebrecht
    Department of Cardiology, Center of Internal Medicine, University Hospital Essen, Essen, Germany
    Catheter Cardiovasc Interv 57:486-95. 2002
    ..The use of a collagen-based closure device is associated with a low rate of clinically significant complications...
  95. ncbi Restick following initial Angioseal use
    Robert J Applegate
    Section of Cardiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Catheter Cardiovasc Interv 58:181-4. 2003
    ..There were no major bleeding, vascular repair, vessel occlusion, or embolizations. Three large hematomas (1.7%) were noted. These data suggest that restick can be performed safely after initial Angioseal deployment...
  96. ncbi Addition of a propyl gallate-based procoagulant to a fibrin bandage improves hemostatic performance in a swine arterial bleeding model
    Stephen W Rothwell
    Department of Blood Research, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Thromb Res 108:335-40. 2002
    ..8+/-66.5 g for TC-S bandage alone, n=12 vs. 121+/-40.7 g, n=13 for the TC-S+HS bandage, P=0.05. Bleeding times were shortened for animals treated with the HS fortified bandages and residual platelets counts in these animals were higher...
  97. ncbi [Evaluation of a hemostatic device with percutaneous collagen application (VasoSeal) compared to a mechanical compression system (Compressar) after transfemoral catheterization of patients suffering from arterial occlusive disease]
    A Neudecker
    Institut für Röntgendiagnostik, Klinikum der Universitat Regensburg
    Rofo 175:676-81. 2003
    ..Comparison of the efficacy of VasoSeal and a mechanical compression system (Compressar) for percutaneous hemostasis after femoral arterial catheterization of patients with arterial occlusive disease...
  98. ncbi Arterial hemostasis using the Duett sealing device
    Kevin W Dickey
    Division of Vascular and Interventional Radiology, Dartmouth Hitchcock Medical Center, Dartmouth Medical School, Lebanon, NH 03756, USA
    Tech Vasc Interv Radiol 6:85-91. 2003
    ..The Duett sealing device is simple to use, safe, effective and a viable alternative to other available devices and/or manual compression...
  99. ncbi Reduced vascular complications after percutaneous coronary interventions with a nonmechanical suture device: results from the randomized RACE study
    Timothy A Sanborn
    Evanston Northwestern Healthcare, Evanston, Illinois 60201, USA
    Catheter Cardiovasc Interv 61:327-32. 2004
    ..The incidence of major complications after PCI was reduced with the device...
  100. ncbi What is the proper activated clotting time (ACT) at which to remove a femoral sheath after PCI? What are the best "protocols" for sheath removal?
    Annmarie Galli
    The Medicines Company, Waltham, Mass, USA
    Crit Care Nurse 25:88-92, 94-5. 2005
  101. ncbi Evaluation of hydrogel tissue sealant in porcine laparoscopic partial-nephrectomy model
    Jonathan E Bernie
    Department of Urology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Endourol 19:1122-6. 2005
    ..b>Hemostatic techniques can include intracorporeal suturing, vascular coagulation (argon-beam coagulator, bipolar cautery, laser), ..

Research Grants58

  1. Reducing Mortality from Acute Hemorrhage in Trauma
    John Hess; Fiscal Year: 2006
    ..Reducing death from acute hemorrhage in trauma care will be a major step forward in reducing overall trauma mortality. ..
  2. UTERINE TUMOR TREATMENT USING HIGH INTENSITY ULTRASOUND
    Shahram Vaezy; Fiscal Year: 2003
    ..Ultimately, this treatment approach may also provide an option to preserve fertility and improve reproductive outcomes in patients with fibroid tumors. ..
  3. ORGAN HEMOSTASIS IN TRAUMA BY HIGH INTENSITY ULTRASOUND
    Shahram Vaezy; Fiscal Year: 2003
    ..Thus, the investigators believe that their proposed studies will result in a new and clinically applicable methodology for reducing mortality and morbidity in abnormal trauma. ..
  4. Focused Ultrasound for Treatment of Nerves
    Shahram Vaezy; Fiscal Year: 2008
    ..It is our goal to develop image- guided focused ultrasound as a non-invasive alternative for the treatment of spasticity and pain. ..
  5. Focused Ultrasound for Treatment of Nerves
    Shahram Vaezy; Fiscal Year: 2007
    ..It is our goal to develop image guided focused ultrasound as a non-invasive alternative for the treatment of spasticity and pain. [unreadable] [unreadable] [unreadable]..
  6. Chitosan hemostatic device for laparoscopic applications
    Hua Xie; Fiscal Year: 2005
    ..abstract_text> ..
  7. Mechanism of Traumatic Coagulopathy
    Mitchell Cohen; Fiscal Year: 2008
    ..Aim 3 entails dynamic modeling based on the results of Aim 1 and 2 data and as such is an interesting approach. The question is how will it be validated as reflective of what occurs in trauma patients? ..
  8. 5-Year Survival Following Injury in Geriatric Patients
    Laura Criddle; Fiscal Year: 2006
    ..Contribution: This foundational study will provide basic information about the survival patterns of injured elders as a basis for the development of interventions to improve geriatric survival. [unreadable] [unreadable] [unreadable]..
  9. An Automated System to Monitor Medical Device Safety
    Frederic Resnic; Fiscal Year: 2006
    ..This approach can be readily extended to monitor the safety of technologies outside of interventional cardiology as outcomes data repositories become available. ..
  10. Regulation of Stellate Cell Contractility
    Don Rockey; Fiscal Year: 2005
    ..Physiologic endpoints will be an important focus. The proposed studies will shed light on the molecular basis of stellate cell contractility and moreover have direct relevance to human liver disease. ..
  11. UGI Hemorrhage and Barrett's Epithelium
    Dennis Jensen; Fiscal Year: 2007
    ..This award will continue to enhance the applicant's research productivity and provide skilled mentoring for young investigators, so they can become independent patient-oriented investigators in digestive diseases. ..
  12. GASTROENTEROLOGY
    Dennis Jensen; Fiscal Year: 2007
    ..Continued support is needed to maintain the quality and productivity of this program which is training future academicians in digestive diseases. ..
  13. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2007
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. [unreadable] [unreadable]..
  14. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2004
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  15. Regulation of Stellate Cell Contractility
    Don Rockey; Fiscal Year: 2007
    ..Physiologic endpoints will be an important focus. The proposed studies will shed light on the molecular basis of stellate cell contractility and moreover have direct relevance to human liver disease. ..
  16. UIC Program for Interdisciplinary Careers in Women's Health Research
    Stacie Geller; Fiscal Year: 2007
    ..Work in women's health ranges from the molecular and cellular level to the community level; these levels are inter-related. Therefore, UlC's research programs are translational and incorporate multiple levels of analysis. ..
  17. An Automated System to Monitor Medical Device Safety
    Frederic Resnic; Fiscal Year: 2007
    ..This approach can be readily extended to monitor the safety of technologies outside of interventional cardiology as outcomes data repositories become available. ..
  18. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don C Rockey; Fiscal Year: 2010
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  19. Nitric Oxide and the Cellular Pathogenesis of Portal Hypertension
    Don C Rockey; Fiscal Year: 2010
    ..This leads to intestinal bleeding and severe clinical consequences. This proposal aims to understand the cause of elevated resistance to blood flow and would shed light on potential treatments for this problem. ..
  20. An Automated System to Monitor Medical Device Safety
    Frederic Resnic; Fiscal Year: 2009
    ..This approach can be readily extended to monitor the safety of technologies outside of interventional cardiology as outcomes data repositories become available. ..
  21. CORE-Instrument Development Laboratory
    Kirk Beach; Fiscal Year: 2008
    ..The overall objective of the IDL Core is to support all phases of the research cycle. ..
  22. Nitric Oxide and the Cellular Pathogenesis of Portal Hypertension
    Don Rockey; Fiscal Year: 2009
    ..This leads to intestinal bleeding and severe clinical consequences. This proposal aims to understand the cause of elevated resistance to blood flow and would shed light on potential treatments for this problem. ..
  23. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2009
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  24. UIC Program for Interdisciplinary Careers in Women's Health Research
    Stacie Geller; Fiscal Year: 2008
    ..Work in women's health ranges from the molecular and cellular level to the community level; these levels are inter-related. Therefore, UlC's research programs are translational and incorporate multiple levels of analysis. ..
  25. An Automated System to Monitor Medical Device Safety
    Frederic Resnic; Fiscal Year: 2008
    ..This approach can be readily extended to monitor the safety of technologies outside of interventional cardiology as outcomes data repositories become available. ..
  26. UGI Hemorrhage and Barrett's Epithelium
    Dennis Jensen; Fiscal Year: 2008
    ..This award will continue to enhance the applicant's research productivity and provide skilled mentoring for young investigators, so they can become independent patient-oriented investigators in digestive diseases. ..
  27. GASTROENTEROLOGY
    Dennis Jensen; Fiscal Year: 2008
    ..Continued support is needed to maintain the quality and productivity of this program which is training future academicians in digestive diseases. ..
  28. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2008
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  29. Regulation of Stellate Cell Contractility
    Don Rockey; Fiscal Year: 2008
    ..Physiologic endpoints will be an important focus. The proposed studies will shed light on the molecular basis of stellate cell contractility and moreover have direct relevance to human liver disease. ..
  30. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2006
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. [unreadable] [unreadable]..
  31. QUANTIFICATION OF FACTORS LEADING TO VEIN GRAFT FAILURE
    JOHN KUCEWICZ; Fiscal Year: 2002
    ..By developing methods to detect the early indicators of impending failure, this project offers the opportunity to extend the useful life of the grafts by permitting early treatment of the lesions. ..
  32. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2002
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  33. PROSPECTIVE COMPARISON OF COLONIC IMAGING TEST
    Don Rockey; Fiscal Year: 2001
    ..The information gained from this study is expected to form the basis for national policy and decision making with reward to colonic imaging tests. ..
  34. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2001
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  35. QUANTIFICATION OF FACTORS LEADING TO VEIN GRAFT FAILURE
    JOHN KUCEWICZ; Fiscal Year: 2001
    ..By developing methods to detect the early indicators of impending failure, this project offers the opportunity to extend the useful life of the grafts by permitting early treatment of the lesions. ..
  36. PROSPECTIVE COMPARISON OF COLONIC IMAGING TEST
    Don Rockey; Fiscal Year: 2000
    ..The information gained from this study is expected to form the basis for national policy and decision making with reward to colonic imaging tests. ..
  37. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2000
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  38. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 1999
    ..These studies have direct relevance to human liver disease and are likely to lead to new approaches for the treatment of portal hypertension, hepatic fibrosis and possibly other forms of fibrosing injury. ..
  39. Nitric Oxide and the Liver
    Don Rockey; Fiscal Year: 2003
    ..The dates of the entire AASLD scientific meeting are November 3rd to November 5th. The participants will be invited speakers and attendees of the annual 2002 AASLD meeting. ..
  40. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2003
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  41. Regulation of Stellate Cell Contractility
    Don Rockey; Fiscal Year: 2006
    ..Physiologic endpoints will be an important focus. The proposed studies will shed light on the molecular basis of stellate cell contractility and moreover have direct relevance to human liver disease. ..
  42. Functional Ultrasonic Tissue Pulsatility: Brain Imaging
    JOHN KUCEWICZ; Fiscal Year: 2005
    ..This new ultrasonic method holds the promise of extremely low cost. Currently, ultrasound instruments with similar complexity can be purchased at prices affordable by primary care clinics. ..
  43. A System to Monitor Safety in Interventional Cardiology
    Frederic Resnic; Fiscal Year: 2005
    ..Once validated, the analytic software will be made publicly available. ..
  44. Regulation of Stellate Cell Contractility
    Don Rockey; Fiscal Year: 2005
    ..Physiologic endpoints will be an important focus. The proposed studies will shed light on the molecular basis of stellate cell contractility and moreover have direct relevance to human liver disease. ..
  45. A System to Monitor Safety in Interventional Cardiology
    Frederic Resnic; Fiscal Year: 2004
    ..Once validated, the analytic software will be made publicly available. ..
  46. Functional Ultrasonic Tissue Pulsatility: Brain Imaging
    JOHN KUCEWICZ; Fiscal Year: 2004
    ..This new ultrasonic method holds the promise of extremely low cost. Currently, ultrasound instruments with similar complexity can be purchased at prices affordable by primary care clinics. ..
  47. Functional Ultrasonic Tissue Pulsatility: Brain Imaging
    JOHN KUCEWICZ; Fiscal Year: 2003
    ..This new ultrasonic method holds the promise of extremely low cost. Currently, ultrasound instruments with similar complexity can be purchased at prices affordable by primary care clinics. ..
  48. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2004
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  49. Regulation of Stellate Cell Contractility
    Don Rockey; Fiscal Year: 2004
    ..Physiologic endpoints will be an important focus. The proposed studies will shed light on the molecular basis of stellate cell contractility and moreover have direct relevance to human liver disease. ..
  50. A System to Monitor Safety in Interventional Cardiology
    Frederic Resnic; Fiscal Year: 2003
    ..Once validated, the analytic software will be made publicly available. ..