relaxation

Summary

Summary: Activity which reduces feelings of tension.

Top Publications

  1. ncbi Mozart versus new age music: relaxation states, stress, and ABC relaxation theory
    Jonathan C Smith
    Roosevelt University Stress Institute, Roosevelt University, Chicago, IL 60605, USA
    J Music Ther 41:215-24. 2004
  2. ncbi Differences in relaxation by means of guided imagery in a healthy community sample
    Eri Watanabe
    Department Health Promotion and Human Behavior, Kyoto University Graduate School of Public Health, Japan
    Altern Ther Health Med 12:60-6. 2006
  3. ncbi Comparative efficacy, speed, and adverse effects of three PTSD treatments: exposure therapy, EMDR, and relaxation training
    Steven Taylor
    Department of Psychiatry, University of British Columbia, Vancouver, Canada
    J Consult Clin Psychol 71:330-8. 2003
  4. ncbi Immune modulation in response to stress and relaxation
    - Mahbub-E-Sobhani
    Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna 9208, Bangladesh
    Pak J Biol Sci 14:363-74. 2011
  5. doi The development of a patient-centered program based on the relaxation response: the Relaxation Response Resiliency Program (3RP)
    Elyse R Park
    Massachusetts General Hospital Benson Henry Institute for Mind Body Medicine, Boston, MA 02114, USA
    Psychosomatics 54:165-74. 2013
  6. doi A comparison of the effect of attention training and relaxation on responses to pain
    L Sharpe
    Clinical Psychology Unit, School of Psychology, University of Sydney, NSW 2006, Australia
    Pain 150:469-76. 2010
  7. ncbi Clinical applications of the relaxation response and mind-body interventions
    G D Jacobs
    Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Altern Complement Med 7:S93-101. 2001
  8. ncbi Lavender fragrance cleansing gel effects on relaxation
    Tiffany Field
    Touch Research Institutes, University of Miami School of Medicine, Miami, Florida 33101, USA
    Int J Neurosci 115:207-22. 2005
  9. ncbi Effects of excitative and sedative music on subjective and physiological relaxation
    M Iwanaga
    Department of Behavioral Sciences, Faculty of Integrated Arts and Sciences, Hiroshima University, Japan
    Percept Mot Skills 85:287-96. 1997
  10. ncbi A controlled study of the effects of mental relaxation on autonomic excitatory responses in healthy subjects
    D Lucini
    Centro Ricerca Neurovegetativa, Ospedale L Sacco, Universita di Milano, Italy
    Psychosom Med 59:541-52. 1997

Research Grants

  1. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
  2. Ang II and Aldosterone Effects on Insulin Resistance in Cardiovascular Tissue
    JAMES RUSSELL SOWERS; Fiscal Year: 2013
  3. JAMES RUSSELL SOWERS; Fiscal Year: 2015
  4. Skeletal Muscle. Ca Release Control Inside the Sarcoplasmic Reticulum.
    Eduardo Rios; Fiscal Year: 2013
  5. ALTERED CARDIAC MYOCYTE SIGNALING IN DIABETIC MYOCARDIUM AND FUNCTIONAL SEQUELAE
    ANTHONY JUSTIN MUSLIN; Fiscal Year: 2010
  6. Gene Therapy with Cardiotropic Vectors for the Treatment of Heart Failure
    Roger J Hajjar; Fiscal Year: 2013
  7. JAMES RUSSELL SOWERS; Fiscal Year: 2016
  8. Gregory L Stahl; Fiscal Year: 2016
  9. Myosin phosphatase autoinhibition in gastrointestinal smooth muscle contraction
    Avril V Somlyo; Fiscal Year: 2012
  10. Design and Synthesis of Anxioselective Anxiolytics
    James M Cook; Fiscal Year: 2010

Detail Information

Publications208 found, 100 shown here

  1. ncbi Mozart versus new age music: relaxation states, stress, and ABC relaxation theory
    Jonathan C Smith
    Roosevelt University Stress Institute, Roosevelt University, Chicago, IL 60605, USA
    J Music Ther 41:215-24. 2004
    Smith's (2001) Attentional Behavioral Cognitive (ABC) relaxation theory proposes that all approaches to relaxation (including music) have the potential for evoking one or more of 15 factor-analytically derived relaxation states, or "R-..
  2. ncbi Differences in relaxation by means of guided imagery in a healthy community sample
    Eri Watanabe
    Department Health Promotion and Human Behavior, Kyoto University Graduate School of Public Health, Japan
    Altern Ther Health Med 12:60-6. 2006
    This study investigated differences in relaxation induced by guided imagery in healthy community samples.
  3. ncbi Comparative efficacy, speed, and adverse effects of three PTSD treatments: exposure therapy, EMDR, and relaxation training
    Steven Taylor
    Department of Psychiatry, University of British Columbia, Vancouver, Canada
    J Consult Clin Psychol 71:330-8. 2003
    ..and incidence of symptom worsening for 3 treatments of posttraumatic stress disorder (PTSD): prolonged exposure, relaxation training, or eye movement desensitization and reprocessing (EMDR; N = 60)...
  4. ncbi Immune modulation in response to stress and relaxation
    - Mahbub-E-Sobhani
    Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna 9208, Bangladesh
    Pak J Biol Sci 14:363-74. 2011
    ..network the effects of psychological stress (acute, brief naturalistic and chronic) and relaxation on immune modulation has been shown...
  5. doi The development of a patient-centered program based on the relaxation response: the Relaxation Response Resiliency Program (3RP)
    Elyse R Park
    Massachusetts General Hospital Benson Henry Institute for Mind Body Medicine, Boston, MA 02114, USA
    Psychosomatics 54:165-74. 2013
    ..Dr. Benson highlighted how the mind and body function together in one's experience of the stress response and proposed the existence of the relaxation response (RR).
  6. doi A comparison of the effect of attention training and relaxation on responses to pain
    L Sharpe
    Clinical Psychology Unit, School of Psychology, University of Sydney, NSW 2006, Australia
    Pain 150:469-76. 2010
    ..Participants were then re-randomized to receive either ATT or progressive muscle relaxation (PMR). Hence, the present study had a 2 (threat expectancy: high vs. low)x2 (training: ATT vs. PMR) design...
  7. ncbi Clinical applications of the relaxation response and mind-body interventions
    G D Jacobs
    Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Altern Complement Med 7:S93-101. 2001
    Several hundred peer-reviewed studies in the past 20 years have shown that the relaxation response and mind-body interventions are clinically effective in the treatment of many health problems that are caused or made worse by stress...
  8. ncbi Lavender fragrance cleansing gel effects on relaxation
    Tiffany Field
    Touch Research Institutes, University of Miami School of Medicine, Miami, Florida 33101, USA
    Int J Neurosci 115:207-22. 2005
    ..The self-report and physiological data are consistent with relaxation profiles during other sensory stimuli such as massage and music, as reported in the literature...
  9. ncbi Effects of excitative and sedative music on subjective and physiological relaxation
    M Iwanaga
    Department of Behavioral Sciences, Faculty of Integrated Arts and Sciences, Hiroshima University, Japan
    Percept Mot Skills 85:287-96. 1997
    ..This result suggests that musical effect was observed in measures of the parasympathetic nervous system but not in the sympathetic nervous system...
  10. ncbi A controlled study of the effects of mental relaxation on autonomic excitatory responses in healthy subjects
    D Lucini
    Centro Ricerca Neurovegetativa, Ospedale L Sacco, Universita di Milano, Italy
    Psychosom Med 59:541-52. 1997
    ..Accordingly, it might be useful to study the effects of behavioral interventions, such as mental relaxation, that might be capable of blunting excitatory autonomic responses...
  11. ncbi Treatment of menopausal symptoms with applied relaxation: a pilot study
    K Wijma
    University Hospital, Linkoping, Sweden
    J Behav Ther Exp Psychiatry 28:251-61. 1997
    Applied relaxation (AR) was tested in a series of six women with postmenopausal hot flushes. The AR program consisted of group instructions 1 hour per week over a 12 week duration...
  12. ncbi Early experiences with tobacco among women smokers, ex-smokers, and never-smokers
    O F Pomerleau
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, USA
    Addiction 93:595-9. 1998
    ..Recent research suggests that people who become smokers may be more sensitive to the positive effects of nicotine than those who do not take up smoking...
  13. ncbi Source localization of EEG activity during hypnotically induced anxiety and relaxation
    T Isotani
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, Lenggstrasse 31, CH 8029, Zurich, Switzerland
    Int J Psychophysiol 41:143-53. 2001
    ..We studied brain electric activity during hypnotically induced anxiety and relaxation in 11 right-handed normals (5 males, 6 females, mean age 26.5+/-7.6 years)...
  14. ncbi The physiology of mind-body interactions: the stress response and the relaxation response
    G D Jacobs
    Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Altern Complement Med 7:S83-92. 2001
    ..Recent studies using spectral analysis and topographic electroencephalographic (EEG) mapping of the relaxation response demonstrate that by changing mental activity we can demonstrate measurable changes in central nervous ..
  15. ncbi Yoga-based guided relaxation reduces sympathetic activity judged from baseline levels
    R P Vempati
    Swami Vivekananda Yoga Research Foundation, Chamarajpet, Bangalore, India
    Psychol Rep 90:487-94. 2002
    35 male volunteers whose ages ranged from 20 to 46 years were studied in two sessions of yoga-based guided relaxation and supine rest...
  16. ncbi Treatment of panic disorder via the Internet: a randomized trial of CBT vs. applied relaxation
    Per Carlbring
    Department of Psychology, Uppsala University, Box 1225, Uppsala, SE 751 42, Sweden
    J Behav Ther Exp Psychiatry 34:129-40. 2003
    ..structured clinical interview for DSM-IV (SCID) interview 22 participants were randomized to either applied relaxation (AR) or a multimodal treatment package based on cognitive behavioral therapy (CBT)...
  17. ncbi S-adenosyl-L-methionine: effects on brain bioenergetic status and transverse relaxation time in healthy subjects
    Marisa M Silveri
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Biol Psychiatry 54:833-9. 2003
    ..were employed to test if S-adenosyl-L-methionine supplementation alters brain bioenergetics and/or transverse relaxation time (T2RT) in a nondepressed cohort...
  18. ncbi Effects of acute stress, relaxation, and a neurogenic inflammatory stimulus on interleukin-6 in humans
    Susan K Lutgendorf
    Department of Psychology, E11 Seashore Hall, University of Iowa, Iowa City, IA 52242, USA
    Brain Behav Immun 18:55-64. 2004
    Effects of three experimental manipulations: mental stress, relaxation, and a nociceptive inflammatory stimulus, capsaicin, on levels of interleukin-6 (IL-6) were examined...
  19. ncbi Recollections and repercussions of the first inhaled cigarette
    Joseph R DiFranza
    Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, USA
    Addict Behav 29:261-72. 2004
    ..It has not been determined if a youth's reaction to the first smoking experience is predictive of future nicotine dependence, or whether the impact of the first cigarette can be altered by manipulating levels of tar, nicotine and menthol...
  20. ncbi The relaxing effect of negative air ions on ambulatory surgery patients
    Hiroshi Iwama
    Can J Anaesth 51:187-8. 2004
  21. ncbi Effects of music listening and relaxation instructions on arousal changes and the working memory task in older adults
    Eri Hirokawa
    University of Kansas, USA
    J Music Ther 41:107-27. 2004
    The purpose of this study was to examine the effects of subject-preferred music and relaxation instructions on older adults' arousal and working memory...
  22. ncbi Relaxation as a cognitive task
    L Sebastiani
    Dipartimento di Fisiologia e Biochimica, Via S Zeno 31, 56127 Pisa, Italy
    Arch Ital Biol 143:1-12. 2005
    ..Results suggest that Highs and Lows used different cognitive strategies in the elaboration of the relaxation request and that Highs performed the task through a higher integrative activity.
  23. ncbi The biomechanical and clinical significance of the lumbar erector spinae flexion-relaxation phenomenon: a review of literature
    Christopher J Colloca
    Department of Kinesiology, Exercise and Sport Science Research Institute, Arizona State University, Tempe, Arizona, USA
    J Manipulative Physiol Ther 28:623-31. 2005
    The aim of this study was to review the biomedical literature to ascertain the biomechanical and clinical significance of the lumbar erector spinae flexion-relaxation phenomenon (FRP).
  24. ncbi Association between oxygen consumption and nitric oxide production during the relaxation response
    Jeffery A Dusek
    Mind Body Medical Institute, 824 Boylston Street, Chestnut Hill, MA 02467, USA
    Med Sci Monit 12:CR1-10. 2006
    Mind/body practices that elicit the relaxation response (RR) are currently practiced by over 30% of American adults...
  25. ncbi Gender differences in adolescents' responses to themes of relaxation in cigarette advertising: Relationship to intentions to smoke
    Danae N Dirocco
    Department of Sociomedical Sciences, Columbia University, USA
    Addict Behav 32:205-13. 2007
    ..The purpose of this study was to examine if gender moderates the degree to which the relaxation valence (i.e...
  26. ncbi Corticotropin releasing factor in urine--a possible biochemical marker of fibromyalgia. Responses to massage and guided relaxation
    Irene Lund
    Department of Physiology and Pharmacology, von Eulers väg 4 8, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Neurosci Lett 403:166-71. 2006
    ..Another purpose was to study the effects of massage and guided relaxation, with respect to change in the same variables...
  27. ncbi The relaxation response: reducing stress and improving cognition in healthy aging adults
    Jennifer A Galvin
    Mind Body Medical Institute and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Complement Ther Clin Pract 12:186-91. 2006
    Aging adults are vulnerable to the effects of a negative emotional state. The relaxation response (RR) is a mind-body intervention that counteracts the harmful effects of stress...
  28. ncbi Aftereffects of exercise and relaxation on blood pressure
    Danilo Forghieri Santaella
    Exercise Hemodynamic Laboratory, School of Physical Education and Sport, Hypertension Unit, General Hospital, Heart Institute InCor, University of Sao Paulo, Brazil
    Clin J Sport Med 16:341-7. 2006
    To study the acute aftereffects of exercise and relaxation, performed alone and in combination, on blood pressure (BP) measured at baseline and during stressful conditions.
  29. ncbi Relaxation: molecular and physiological significance
    George B Stefano
    Neuroscience Research Institute, State University of New York College at Old Westbury, Old Westbury, NY 11568, USA
    Med Sci Monit 12:HY21-31. 2006
    There appears to be a molecular process for relaxation. Given this, we attempt to demonstrate this phenomenon based on established molecular and physiological processes in light of our current understanding of central and peripheral ..
  30. ncbi Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans
    Adham M Abdou
    Department of Research and Development, Pharma Foods International Co Ltd, Kyoto, Japan
    Biofactors 26:201-8. 2006
    The effect of orally administrated gamma-aminobutyric acid (GABA) on relaxation and immunity during stress has been investigated in humans. Two studies were conducted...
  31. ncbi Role of relaxation and specific suggestions in hypnotic emotional numbing
    Laura Sebastiani
    Department of Physiology and Biochemistry, University of Pisa, Via San Zeno 31, 56127 Pisa, Italy
    Int J Psychophysiol 63:125-32. 2007
    ..of fear/stress, but also show an EEG pattern indicating a balance between fear-induced arousal and hypnotic relaxation. Indeed, hypnosis is effective in the attenuation of both emotional experience and behaviour (emotional numbing)...
  32. ncbi Mental fatigue-induced decrease in levels of several plasma amino acids
    K Mizuno
    Department of Physiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Neural Transm 114:555-61. 2007
    ..As a control, 8-hr relaxation session was performed in the same subjects at an interval of 4 weeks...
  33. ncbi Normal-appearing brain t1 relaxation time predicts disability in early primary progressive multiple sclerosis
    Francesco Manfredonia
    Department of Brain Repair and Rehabilitation, Institute of Neurology, University College London, London, England
    Arch Neurol 64:411-5. 2007
    To investigate whether patients with early primary progressive multiple sclerosis show changes in T1 relaxation time (T1-RT) in normal-appearing white matter (NAWM) and normal-appearing gray matter (NAGM) during 2 years and whether T1-RT ..
  34. ncbi Expectancies, not aroma, explain impact of lavender aromatherapy on psychophysiological indices of relaxation in young healthy women
    Siobhan Howard
    National University of Ireland, Galway, Ireland
    Br J Health Psychol 13:603-17. 2008
    In aromatherapy, lavender aroma is reputed to assist with relaxation. However, while there is much anecdotal evidence to that effect, the empirical literature is very inconsistent...
  35. pmc Fetal responses to induced maternal relaxation during pregnancy
    Janet A Dipietro
    Department of Population, Family and Reproductive Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, United States
    Biol Psychol 77:11-9. 2008
    Fetal responses to induced maternal relaxation during the 32nd week of pregnancy were recorded in 100 maternal-fetal pairs using a digitized data collection system...
  36. ncbi Negative psychological effects of watching the news in the television: relaxation or another intervention may be needed to buffer them!
    Attila Szabo
    National Institute for Sport Talent Care, Budapest, Hungary
    Int J Behav Med 14:57-62. 2007
    ..n = 179) of undergraduate students who watched a 15-min random newscast followed by either a 15-min progressive relaxation exercise or a 15-min lecture (control condition)...
  37. pmc The combined effect of relaxation response and acupuncture on quality of life in patients with HIV: a pilot study
    Bei Hung Chang
    Department of Health Policy and Management, Boston University School of Public Health, Boston, MA 02130, USA
    J Altern Complement Med 13:807-15. 2007
    ..Some studies have shown the individual effects of acupuncture and the relaxation response (RR) in improving QoL of patients with HIV/AIDS...
  38. ncbi Anticipatory stress response: a significant commonality in stress, relaxation, pleasure and love responses
    George B Stefano
    Neuroscience Research Institute, State University of New York, College at Old Westbury, Old Westbury, NY 11568 0210, USA
    Med Sci Monit 14:RA17-21. 2008
    ..and autoregulatory similarities between different physiological phenomena, particularly with regard to stress, relaxation and love responses, against the background of recent research findings...
  39. doi Differential effects of relaxation techniques on ultraweak photon emission
    Eduard P A Van Wijk
    International Institute of Biophysics, Neuss, Germany
    J Altern Complement Med 14:241-50. 2008
    ..However, most are invasive and none are applicable to all conditions. Attention has recently been drawn to spontaneous ultraweak photon emission (UPE). However, the application of this method in meditation studies is very limited...
  40. doi Effectiveness of relaxation for postoperative pain and anxiety: randomized controlled trial
    Kate Seers
    RCN Research Institute, School of Health and Social Studies, University of Warwick, Coventry, UK
    J Adv Nurs 62:681-8. 2008
    This paper is a report of a study to determine the effectiveness of jaw and total body relaxation for postoperative pain, anxiety and level of relaxation, and to determine any patient expectancy effects.
  41. pmc Simultaneous EEG/functional magnetic resonance imaging at 4 Tesla: correlates of brain activity to spontaneous alpha rhythm during relaxation
    Mark W DiFrancesco
    Division of Pediatric Radiology, Cincinnati Children s Hospital Medical Center, Pediatric Neuroimaging Research Consortium, Cincinnati, Ohio, USA
    J Clin Neurophysiol 25:255-64. 2008
    ....
  42. doi Efficacy of functional relaxation and patient education in the treatment of somatoform heart disorders: a randomized, controlled clinical investigation
    Claas Lahmann
    Department of Psychosomatic Medicine and Psychotherapy, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
    Psychosomatics 49:378-85. 2008
    ..Recurrent heart problems and, especially, chest pain in the absence of somatic heart disease is a common finding, although challenging to treat...
  43. doi Mental and physical fatigue-related biochemical alterations
    Satoshi Nozaki
    Department of Physiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Nutrition 25:51-7. 2009
    To confirm fatigue-related biochemical alterations, we measured various parameters just before and after relaxation and fatigue-inducing mental or physical sessions.
  44. ncbi Immediate effects of two relaxation techniques on healthy volunteers
    Sushilkumar S Khemka
    Swami Vivekananda Yoga Anusanthana Samsthana, Eknath Bhavan, 19, Gavipuram Circle, Bangalore 560 019
    Indian J Physiol Pharmacol 53:67-72. 2009
    This controlled study compared immediate effects of two relaxation techniques on state anxiety and sustained attention in healthy subjects...
  45. ncbi Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian
    Benjamin S Weeks
    Department of Biology, Adelphi University, Garden City, NY 11530, USA
    Med Sci Monit 15:RA256-62. 2009
    ..This review focuses on supplements which have anxiolytic or mild relaxation properties and enhance mood...
  46. doi The physiological and psychological effects of slow-stroke back massage and hand massage on relaxation in older people
    Melodee Harris
    College of Nursing, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    J Clin Nurs 19:917-26. 2010
    ..This review examines the physiological and psychological effects of slow-stroke back massage and hand massage on relaxation in older people and identifies effective protocols for massage in older people.
  47. doi Development of need for recovery from work over one year: a person-centered approach
    Marjo Siltaloppi
    Department of Psychology, University of Tampere, Finland
    Anxiety Stress Coping 25:23-42. 2012
    ..Thus, the antecedents examined play a significant role in maintaining need for recovery over time...
  48. doi A comparative study of 2 manual-based self-help interventions, acceptance and commitment therapy and applied relaxation, for persons with chronic pain
    Jenny Thorsell
    Department of Psychology, Uppsala University, Sweden
    Clin J Pain 27:716-23. 2011
    The aim of this study was to compare 2 self-help-based interventions; a coping-oriented approach, applied relaxation (AR) and an acceptance-oriented approach, acceptance and commitment therapy (ACT), for persons with chronic pain.
  49. doi The shielding function of task sets and its relaxation during task switching
    Gesine Dreisbach
    Department of Experimental Psychology, University of Regensburg, D 93053 Regensburg, Germany
    J Exp Psychol Learn Mem Cogn 37:1540-6. 2011
    The goal of the presented experiments was to investigate the dynamic interplay of task shielding and its relaxation during task switching...
  50. pmc The protocol of a randomized controlled trial for playgroup mothers: Reminder on Food, Relaxation, Exercise, and Support for Health (REFRESH) Program
    Sarojini M D R Monteiro
    Western Australian Centre for Health Promotion Research, School of Public Health, Curtin University, Western Australia, Australia
    BMC Public Health 11:648. 2011
    ..This study aims to confirm if a low-cost, accessible playgroup based intervention program can improve the dietary and physical activity behaviours of mothers with young children...
  51. doi Psychobiological changes from relaxation response elicitation: long-term practitioners vs. novices
    Bei Hung Chang
    Boston University School of Public Health, Department of Health Policy and Management, Boston, MA, USA
    Psychosomatics 52:550-9. 2011
    The relaxation response (RR) is a physiological state that is the counterpart to the stress response...
  52. pmc Water and metabolite transverse T2 relaxation time abnormalities in the white matter in schizophrenia
    Fei Du
    McLean Hospital, Belmont, MA 02478, USA
    Schizophr Res 137:241-5. 2012
    ..provide evidence on tissue structure have been widely used to probe these abnormalities in vivo, but transverse relaxation times (T2) may provide additional insights since they are determined by molecule-microenvironment interactions ..
  53. doi Modulation of somatosensory evoked potentials during force generation and relaxation
    Toshiaki Wasaka
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 4448585, Japan
    Exp Brain Res 219:227-33. 2012
    ..the modulation of somatosensory evoked potentials (SEPs) during precisely controlled force generation and force relaxation in a visuomotor tracking task...
  54. doi Hypnotizability modulates the cardiovascular correlates of subjective relaxation
    Enrica L Santarcangelo
    Department of Physiological Sciences, University of Pisa, Pisa, Italy
    Int J Clin Exp Hypn 60:383-96. 2012
    ..rate (HRV), blood pressure, and skin blood flow were studied in high and low hypnotizable subjects during simple relaxation. Similar subjective relaxation was reported by highs and lows...
  55. pmc Relaxation response induces temporal transcriptome changes in energy metabolism, insulin secretion and inflammatory pathways
    Manoj K Bhasin
    Benson Henry Institute for Mind Body Medicine at Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 8:e62817. 2013
    The relaxation response (RR) is the counterpart of the stress response. Millennia-old practices evoking the RR include meditation, yoga and repetitive prayer...
  56. ncbi Exercise and relaxation in health promotion
    R J Shephard
    School of Physical and Health Education, Faculty of Medicine, University of Toronto, Ontario, Canada
    Sports Med 23:211-7. 1997
    ..If exercise is to be effective in inducing relaxation, it must be noncompetitive, moderate in intensity, and pursued in pleasant surroundings.
  57. ncbi Effects of individualized versus classical "relaxation" music on the frequency of agitation in elderly persons with Alzheimer's disease and related disorders
    L A Gerdner
    Health Services Research and Development, Center for Mental Healthcare and Outcomes Research, Veterans Administration, University of Arkansas for Medical Sciences, Little Rock, USA
    Int Psychogeriatr 12:49-65. 2000
    ..crossover design compared the immediate and residual effects of individualized music to classical "relaxation" music relative to baseline on the frequency of agitated behaviors in elderly persons with Alzheimer's disease ..
  58. ncbi Differentiation of hypnosis and relaxation by analysis of narrow band theta and alpha frequencies
    J D Williams
    Imperial College of Science Technology and Medicine, London, UK Psychology Group, School of Health and Social Sciences, Coventry University, Coventry, CV1 5FB, UK
    Int J Clin Exp Hypn 49:185-206. 2001
    ..These findings common to low and high susceptibles suggest that theta is an index of relaxation that continues after hypnosis in highs...
  59. ncbi Biofeedback-assisted relaxation in migraine headache: relationship to cerebral blood flow velocity in the middle cerebral artery
    Sachinder Vasudeva
    Departments of Psychiatry, Medical College of Ohio, Toledo, Spain
    Headache 43:245-50. 2003
    To determine if migraineurs with aura respond differently to biofeedback/relaxation than those without aura and, if so, whether the variability in outcome can be explained by blood flow velocity. Background...
  60. ncbi Relaxation versus cognitive therapies for dental fear--a psychophysiological approach
    Jesper Lundgren
    Department of Psychology, Goteborg University, Goteborg, Sweden
    Health Psychol 25:267-73. 2006
    ..Before and after either relaxation or cognitively oriented treatment, subjects were exposed to neutral and fear-relevant video sequences while the ..
  61. ncbi An evaluation of two behavioral rehabilitation programs, qigong versus progressive relaxation, in improving the quality of life in cardiac patients
    Peggy Ngor Hui
    Occupational Therapy Department, United Christian Hospital, Hospital Authority, Kwun Tong, Kowloon, Hong Kong
    J Altern Complement Med 12:373-8. 2006
    ..The aim of the current study was to evaluate and compare two different behavioral rehabilitation programs in improving the quality of life in cardiac patients in Hong Kong...
  62. ncbi A comparison of selected osteopathic treatment and relaxation for tension-type headaches
    Rosemary E Anderson
    Toronto Rehabilitation Institute, Toronto, Canada
    Headache 46:1273-80. 2006
    The objective of this study was to compare the effects of osteopathic treatment and progressive muscular relaxation (PMR) exercises on patients with tension-type headache (TTH).
  63. pmc Relaxation response with acupuncture trial in patients with HIV: feasibility and participant experiences
    Bei Hung Chang
    Department of Health Policy and Management, Boston University School of Public Health, Boston, MA 02130, USA
    J Altern Complement Med 13:719-24. 2007
    ..We designed an RCT, which avoided these two common challenges, to evaluate the effect of adding the relaxation response (RR) to usual acupuncture treatment...
  64. pmc Emotional approach coping and self-efficacy moderate the effects of written emotional disclosure and relaxation training for people with migraine headaches
    Christina A Kraft
    Wayne State University, Detroit, Michigan 48202, USA
    Br J Health Psychol 13:67-71. 2008
    We tested whether emotional skills and headache management self-efficacy (HMSE) moderated effects of written emotional disclosure (WED) compared with control writing and a different intervention, relaxation training (RT).
  65. doi Stress management intervention reduces serum cortisol and increases relaxation during treatment for nonmetastatic breast cancer
    Kristin M Phillips
    Department of Psychology, University of Miami, Coral Gables, Florida 33124, USA
    Psychosom Med 70:1044-9. 2008
    To examine the effects of a cognitive-behavioral stress management (CBSM) intervention, which was composed of relaxation, cognitive restructuring, and coping skills training on late afternoon serum cortisol and relaxation indicators in ..
  66. ncbi The effect of psychological stress and relaxation on interoceptive accuracy: Implications for symptom perception
    Stephen H Fairclough
    School of Psychology, Liverpool John Moores University, Liverpool, United Kingdom
    J Psychosom Res 62:289-95. 2007
    ..b>relaxation) would influence heartbeat detection performance in a laboratory environment and (ii) whether interoceptive ..
  67. ncbi Granulocyte activation in humans is modulated by psychological stress and relaxation
    Margit Keresztes
    Medical Faculty, Institute of Biochemistry, University of Szeged, Hungary
    Stress 10:271-81. 2007
    ..of an examination period, which was associated with elevated blood plasma cortisol level, and following relaxation hypnosis in both students, during their examination term, and patients...
  68. ncbi The effect of moderate aerobic exercise and relaxation on secretory immunoglobulin A
    M R Reid
    School of Psychology, Murdoch University, Western Australia, Australia
    Int J Sports Med 22:132-7. 2001
    ..The aim of this paper was to investigate the effect of aerobic exercise and relaxation on various indices of sIgA in 12 male and 8 female adults who varied in levels of recreational activity...
  69. ncbi Contributions of imagery ability to stress and relaxation
    E L Johnsen
    Department of Psychology, University of Iowa, Iowa City 52242, USA
    Ann Behav Med 23:273-81. 2001
    ..This study examined the contribution of imagery ability to psychological and physiological responses to stress and relaxation. Individuals (N = 176) participated in two study sessions...
  70. ncbi Effects of hydrocortisone and beta-aminopropionitrile on stress-strain and stress-relaxation behaviors, and birefringent retardation of collagen fibers in the rat incisor periodontal ligament
    K Komatsu
    Department of Pharmacology, School of Dental Medicine, Tsurumi University, Tsurumi ku, Yokohama, Japan
    Connect Tissue Res 43:581-8. 2002
    ..The shear stress-strain and stress-relaxation properties of the incisor periodontal ligament were examined in transverse sections from dissected mandibles...
  71. ncbi A pilot study addressing the effect of aromatherapy massage on mood, anxiety and relaxation in adult mental health
    Jennifer Edge
    Lavender Day Hospital, Horsham Formerly Sussex Weald and Downs NHS Trust, West Sussex Health and Social Care NHS Trust, UK
    Complement Ther Nurs Midwifery 9:90-7. 2003
    ..The subjects' levels of mood, anxiety and relaxation were recorded using a visual analogue before and after each massage and then again 6 weeks after the last ..
  72. ncbi Worry and heart rate variables: autonomic rigidity under challenge
    Maryanne Davis
    School of Psychology, University of Tasmania, Hobart, Australia
    J Anxiety Disord 16:639-59. 2002
    ..third experiments measured average heart rate and heart period variability (HPV) in worriers and controls during relaxation, non-stressful cognitive tasks, worried thinking, and aversive imagery conditions...
  73. ncbi Auricular acupressure as a treatment for anxiety in prehospital transport settings
    Alexander Kober
    Department of Anesthesiology and General Intensive Care, University Hospital of Vienna, Austria
    Anesthesiology 98:1328-32. 2003
    Auricular acupuncture at the relaxation point has been previously shown to be an effective treatment for anxiety in the preoperative setting...
  74. ncbi Relaxing intraoperative natural sound blunts haemodynamic change at the emergence from propofol general anaesthesia and increases the acceptability of anaesthesia to the patient
    M Tsuchiya
    Department of Biochemistry and Molecular Pathology, Osaka City University Medical School, Abeno Ku, Osaka, Japan
    Acta Anaesthesiol Scand 47:939-43. 2003
    ..As auditory perception has been demonstrated to remain active under general anaesthesia, playing comforting sounds to patients under general anaesthesia might also modulate the response of these patients to surgical stress...
  75. ncbi Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress and levels of cortisol, dehydroepiandrosterone sulfate (DHEAS) and melatonin in breast and prostate cancer outpatients
    Linda E Carlson
    Department of Psychosocial Resources, Tom Baker Cancer Centre, Alberta Cancer Board, 1331 29 Street NW, Calgary, Alta, Canada T2N 4N2
    Psychoneuroendocrinology 29:448-74. 2004
    ....
  76. ncbi [Psychological and physiological evaluations of music listening for mental stress]
    Hiroki Hasegawa
    Department of Computer Science and Systems Engineering, Muroran Institute of Technology, Muroran 050 8585, Japan
    Hokkaido Igaku Zasshi 79:225-35. 2004
    Music elicits emotional and physiological responses in humans, providing excitement, mood elevation, relaxation, sedation and so on...
  77. ncbi Effect of psychological stress on the salivary cortisol and amylase levels in healthy young adults
    Noriyasu Takai
    Department of Physiology, Osaka Dental University, 8 1, Kuzuha hanazono cho, Hirakata, Osaka 573 1121, Japan
    Arch Oral Biol 49:963-8. 2004
    ..We examined the effects of psychological stressor and soother on the salivary cortisol and amylase levels in young adults, and compared the characteristics of these parameters...
  78. ncbi Occurrence of imagery and its link with early memories in agoraphobia
    Samantha J Day
    University College London, UK
    Memory 12:416-27. 2004
    ..While these exploratory findings require replication, potential treatment implications are discussed...
  79. ncbi The effect of mental stress on the non-dipolar components of the T wave: modulation by hypnosis
    Peter Taggart
    Department of Cardiology, The Hatter Institute and Centre for Cardiology, University College London Hospitals, Grafton Way, London WC1E 6DB, UK
    Psychosom Med 67:376-83. 2005
    ..that in the absence of ischemia, mental stress may modulate repolarization by changing autonomic balance; and mental relaxation induced by hypnosis may offset the potentially adverse effects of stress on the cardiac electrophysiology.
  80. ncbi Aromatherapy for outpatients with menopausal symptoms in obstetrics and gynecology
    Shio Murakami
    Green Flask Laboratory, Green Flask Co, Ltd, Tokyo, Japan
    J Altern Complement Med 11:491-4. 2005
    ....
  81. ncbi Patients' existential situation prior to colorectal surgery
    Monica Moene
    Faculty of Health and Caring Sciences, Institute of Nursing, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    J Adv Nurs 54:199-207. 2006
    ..The aim of this paper is to present a hermeneutic phenomenological study illuminating patients' existential situation prior to colorectal surgery. The intention was also to explore the value of the encounter between patient and nurse...
  82. ncbi [Music therapy as a part of complex healing]
    Agnieszka Sliwka
    Akademia Wychowania Fizycznego w Krakowie, Wydział Rehabilitacji Ruchowej
    Pol Merkur Lekarski 21:401-5. 2006
    ..Music therapy is treated as a method which complements conventional treatment and makes up part of an integral whole together with physiotherapy, kinesitherapy and recuperation...
  83. ncbi The effect of preferred music genre selection versus preferred song selection on experimentally induced anxiety levels
    Darcy DeLoach Walworth
    The Florida State University and Tallahassee Memorial Health Care, USA
    J Music Ther 40:2-14. 2003
    ..filled out a questionnaire prior to participating in the study indicating their preference of music used for relaxation purposes...
  84. ncbi Coping with stress: the effectiveness of different types of music
    Elise Labbé
    Department of Psychology, University of South Alabama, Mobile, AL 36688, USA
    Appl Psychophysiol Biofeedback 32:163-8. 2007
    ..should result in significant reductions in anxiety, anger, and sympathetic nervous system arousal, and increased relaxation compared to those who sit in silence or listen to heavy metal music...
  85. ncbi Complementary treatments for tobacco cessation: a survey
    Amit Sood
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Nicotine Tob Res 8:767-71. 2006
    ..The interventions most commonly used were hypnosis, relaxation, acupuncture, and meditation...
  86. ncbi Psychophysiological effects of human-animal interaction: theoretical issues and long-term interaction effects
    Javier Virues-Ortega
    Instituto de Salud Carlos III, Centro Nacional de Epidemiologia, Madrid, Spain
    J Nerv Ment Dis 194:52-7. 2006
    ..1) stress-buffering effects of noncritical social support provided by pets; and (2) classical conditioning of relaxation. These mechanisms may partially account for the long-term health outcomes observed in a number of human-animal ..
  87. ncbi Effects of flotation therapy on relaxation and mental state
    Pei cheng Hu
    Department of Medical Psychology, Peking University Health Science Centre, Beijing 100083, China
    Chin Med J (Engl) 117:1579-81. 2004
  88. pmc Cardiovascular, cerebrovascular, and respiratory changes induced by different types of music in musicians and non-musicians: the importance of silence
    L Bernardi
    Department of Internal Medicine, IRCCS S Matteo, University of Pavia, Pavia, Italy
    Heart 92:445-52. 2006
    ....
  89. ncbi Alarm reaction and serum K+ in hypertensive patients
    F V Costa
    Cattedra di Terapia Medica Sistematica, , Italy
    Am J Hypertens 3:638-40. 1990
    ..The increase in serum K+ induced by relaxation was significantly related to heart rate decrease (r = 0.73)...
  90. ncbi Music for relaxation: a comparison of musicians and nonmusicians on ratings of selected musical recordings
    David E Wolfe
    University of the Pacific, USA
    J Music Ther 39:40-55. 2002
    ..was to determine the kinds of musical selections/CDs to place in a portfolio to be used within a music listening/relaxation program for parents of children in a pediatric hospital...
  91. ncbi Psychological effects of forest environments on healthy adults: Shinrin-yoku (forest-air bathing, walking) as a possible method of stress reduction
    E Morita
    Department of Health Promotion and Human Behaviour, Graduate School of Medicine, Kyoto University, Yoshida Konoe, Sakyo ku, Kyoto 606 8501, Japan
    Public Health 121:54-63. 2007
    Shinrin-yoku (walking and/or staying in forests in order to promote health) is a major form of relaxation in Japan; however, its effects have yet to be completely clarified...
  92. ncbi Perceived health is associated with visiting natural favourite places in the vicinity
    Kalevi M Korpela
    Department of Psychology, University of Tampere, 33014 Tampere, Finland
    Health Place 13:138-51. 2007
    ..The change toward positive feelings was associated in particular with natural favourite places and relaxing in them. The results give impetus to research on the self-regulation of mood and neighbourhood context in health...
  93. pmc The influence of anger expression on wound healing
    Jean Philippe Gouin
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 22:699-708. 2008
    ..This enhanced cortisol secretion was in turn related to longer time to heal. These findings suggest that the ability to regulate the expression of one's anger has a clinically relevant impact on wound healing...
  94. ncbi Stress and methods of dealing with it among students of Arts Departments at the UMCS
    D Zołnierczuk-Kieliszek
    Miedzywydziałowa Katedra i Zakład Zdrowia Publicznego, Akademii Medycznej w Lublinie
    Ann Univ Mariae Curie Sklodowska Med 54:235-40. 1999
    ..The research results were confronted with similar survey carried out among students of the Faculty of Medicine at Medical University...
  95. ncbi Stress and methods of dealing with it among the students of the Faculty of Medicine of Medical University in Lublin
    D Zołnierczuk-Kieliszek
    Miedzywydziałowa Katedra i Zakład Zdrowia Publicznego, Akademii Medycznej w Lublinie
    Ann Univ Mariae Curie Sklodowska Med 54:227-33. 1999
    ..The analysis of these kinds of behaviour according to such factors: sex, social background and temporary or permanent residence of the subject was carried out...
  96. ncbi [Psychological stress in oncology: the role of glucocorticoids]
    Alain Ronson
    Psychiatre, Institut Jules Bordet, Clinique de Psycho Oncologie, 121, boulevard de Waterloo, 1000 Bruxelles
    Bull Cancer 93:699-708. 2006
    ..Such advances could lead to profound changes in the way we understand and treat psychological distress in patients with cancer, both pharmacologically and psychotherapeutically...
  97. ncbi Complementary and alternative medicine for low-back pain in pregnancy: a cross-sectional survey
    Shu Ming Wang
    Department of Anesthesiology, Yale University School of Medicine, New Haven, CT 06518, USA
    J Altern Complement Med 11:459-64. 2005
    ..To identify common treatments used for low-back pain (LBP) during pregnancy...
  98. doi Mind-body interventions during pregnancy
    Amy E Beddoe
    School of Nursing, San Jose State University, CA 95192 0057, USA
    J Obstet Gynecol Neonatal Nurs 37:165-75. 2008
    ..To examine published evidence on the effectiveness of mind-body interventions during pregnancy on perceived stress, mood, and perinatal outcomes...
  99. ncbi Yoga: an adjunct to infertility treatment
    Hari Kaur Khalsa
    West Medford, MA 02155, USA
    Fertil Steril 80:46-51. 2003
    Yoga and meditation can help women experiencing the challenges of infertility. The practice of meditation and relaxation can help increase the clarity of the mind, maintain healthy body chemistry, and give patients the patience to undergo ..
  100. ncbi Effects of flotation-restricted environmental stimulation technique on stress-related muscle pain: what makes the difference in therapy--attention-placebo or the relaxation response?
    Sven A Bood
    Department of Psychology, Karlstad University, SE 651 88 Karlstad, Sweden
    Pain Res Manag 10:201-9. 2005
    ..Flotation-restricted environmental stimulation technique is a method whereby an individual lies in a floating tank and all stimuli are reduced to a minimum...
  101. ncbi The repose of wellbeing
    Susan Vorce Crocker
    Nebr Nurse 41:13. 2008

Research Grants72

  1. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
  2. Ang II and Aldosterone Effects on Insulin Resistance in Cardiovascular Tissue
    JAMES RUSSELL SOWERS; Fiscal Year: 2013
    ..activates ROS/ROK pathways leading to impairment of vasorelaxation, myocardial glucose utilization and diastolic relaxation because of ROK induced site-specific Ser phosphorylation of IRS-1...
  3. JAMES RUSSELL SOWERS; Fiscal Year: 2015
    ..INS metabolic signaling and biological consequences, such as impaired nitric oxide (NO)-mediated vascular relaxation. This proposal seeks to investigate novel molecular mechanisms by which ANG II and over-nutrition individually ..
  4. Skeletal Muscle. Ca Release Control Inside the Sarcoplasmic Reticulum.
    Eduardo Rios; Fiscal Year: 2013
    ..its patterns of interest cover multiple time scales: milliseconds -Ca2+ movements that determine contraction and relaxation-;seconds to minutes -when sustained activity may lead to myogenic fatigue- and hours to weeks -patterns that ..
  5. ALTERED CARDIAC MYOCYTE SIGNALING IN DIABETIC MYOCARDIUM AND FUNCTIONAL SEQUELAE
    ANTHONY JUSTIN MUSLIN; Fiscal Year: 2010
    ..or coronary artery disease and that is characterized by ventricular hypertrophy, decreased ventricular diastolic relaxation, and a reduced peak filling rate...
  6. Gene Therapy with Cardiotropic Vectors for the Treatment of Heart Failure
    Roger J Hajjar; Fiscal Year: 2013
    ..Deficient SR Ca2+ uptake during relaxation has been identified in failing hearts from both humans and animal models and has been associated with a decrease ..
  7. JAMES RUSSELL SOWERS; Fiscal Year: 2016
    ..INS metabolic signaling and biological consequences, such as impaired nitric oxide (NO)-mediated vascular relaxation. This proposal seeks to investigate novel molecular mechanisms by which Ang II, aldosterone and a WD ..
  8. Gregory L Stahl; Fiscal Year: 2016
    ..e., loss of endothelium-dependent relaxation) and cardiomyopathy (i.e., left ventricular dysfunction, hypertrophy and cardiac fibrosis)...
  9. Myosin phosphatase autoinhibition in gastrointestinal smooth muscle contraction
    Avril V Somlyo; Fiscal Year: 2012
    ..while cAMP/cGMP signals and the cyclic nucleotide target, telokin, reverse the inhibitory effect, causing GI SM relaxation. Our collaboration has lead to a novel model for the mechanism underlying the inhibition of MLCP activity upon ..
  10. Design and Synthesis of Anxioselective Anxiolytics
    James M Cook; Fiscal Year: 2010
    ..It is also active in primates in the conflict paradigm with no signs of muscle relaxation, or ataxia or sedation. The prodrug (2) of this anxiolytic agent exhibits a similar profile in rodents...
  11. Nitric Oxide and gastric motility in female diabetics
    Pandu R Gangula; Fiscal Year: 2010
    ..Our preliminary data suggests that a significant impairment of nitrergic relaxation and delayed gastric emptying for solids was demonstrated selectively in females after diabetes induction with ..
  12. Potentiation of Glycine Receptors by Ethanol
    LUIS GERARDO AGUAYO; Fiscal Year: 2010
    ..receptors by toxins and drugs such as ethanol leads to a wide range of effects varying from sedation and muscle relaxation to convulsions, respiratory arrest and death...
  13. John P Forman; Fiscal Year: 2016
    ..Besides serving as an antioxidant, melatonin suppresses sympathetic outflow, promotes vascular relaxation, and affects insulin secretion...
  14. Zbigniew Darzynkiewicz; Fiscal Year: 2014
    ..changes in the maximal pixel intensity of fluorescence of DNA-bound fluorescent ligands, a reporter of chromatin relaxation, the initial event in a cell's DNA damage response (DDR)...
  15. HUA LINDA CAI; Fiscal Year: 2016
    ..This shares some similarity with endothelium regulation of vascular smooth muscle relaxation and signaling in conduit arteries...
  16. Innate Immunity and Cardiovascular Function
    Gregory L Stahl; Fiscal Year: 2010
    ..e., loss of endothelium-dependent relaxation) and cardiomyopathy (i.e., left ventricular dysfunction, hypertrophy and cardiac fibrosis)...
  17. Epigenetic Regulation Of Sex-dependent Liver Cancer
    Arlin B Rogers; Fiscal Year: 2012
    ..Nevertheless, while nucleosomal relaxation may facilitate required Stat5b access to g-associated sequences (GAS) and other DNA motifs, an unintended ..
  18. Raouf A Khalil; Fiscal Year: 2016
    ..perfusion pressure (RUPP) in late pregnant rats is associated with HTN, increased vasoconstriction and reduced relaxation. In search for the mechanisms linking RUPP to HTN, we have found that elevation of plasma levels of tumor ..
  19. SMOOTH MUSCLE MYOSIN PHOSPHATASE SUBUNIT ISOFORMS
    Steven A Fisher; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Myosin phosphatase (MP) is the primary effector of smooth muscle relaxation and a key target of signaling pathways that regulate vessel tone...
  20. Function and regulation of elemental Ca2+ signaling in urethral smooth muscle
    Ronghua Zhuge; Fiscal Year: 2013
    ..and NO, we will establish that PE and NO differentially modulate RyR2 and ANO1, resulting in the contraction and relaxation of urethra, respectively (Aim 3)...
  21. Genomic actions of progesterone receptors in human myometrial cells
    Sam Mesiano; Fiscal Year: 2010
    ..Those observations have led to the PR-A/PR-B hypothesis, which posits that a) progesterone promotes myometrial relaxation during most of human pregnancy via PR-B, which modulates the expression of a specific cohort of relaxatory genes,..
  22. Warren G Hill; Fiscal Year: 2014
    ..are strongly indicative of an obstructed bladder phenotype possibly due to inadequate urethral sphincter relaxation. Taken together these symptoms indicate a mechanical signaling deficit originating in the urothelium which leads ..
  23. PTSD Hyperarousal Symptoms Treated with Physiological Stress Management
    WALTON THOMPSON ROTH; Fiscal Year: 2011
    ..with PTSD related to combat experience in the last 10 years and to test the efficacy of physiological relaxation training in reducing this hyperarousal...
  24. Redox Regulation of SERCA by Nitric Oxide
    Richard A Cohen; Fiscal Year: 2013
    ..C674S knock-in (SKI+/-) mice that preliminary studies show have abnormal 7NO-stimulated SERCA activity and relaxation, and decreased VEGF- and ischemia-induced angiogenesis...
  25. IVAN B YANACHKOV; Fiscal Year: 2015
    ..P2Y4, P2Y6, or P2X1 receptors, and had good safety margin in the endothelium P2Y-dependent guinea pig aorta relaxation model...
  26. Khalid Matrougui; Fiscal Year: 2014
    ..receptor gene) associated with coronary arteriolar dysfunction characterized by a reduced endothelial-dependent relaxation and potentiation of myogenic tone...
  27. Cardiomyocyte Zinc and its Regulation of Contraction-Relaxation Function
    Bradley M Palmer; Fiscal Year: 2012
    ..an elevation in intracellular zinc ion concentration ([Zn2+]int) in the isolated cardiomyocyte leads to improved relaxation dynamics...
  28. Gary M Brittenham; Fiscal Year: 2014
    ..by the high-Tc susceptometer with (i) estimates derived from liver magnetic resonance imaging (MRI) relaxation rates (R2, R2*, signal intensity ratios), (ii) with determinations of serum ferritin, and (iii) with ..
  29. Blood Pressure -- Determinants &Controllers
    Allen W Cowley; Fiscal Year: 2012
    ..reactivity and how defects in the SS renin allele lead to increased oxidative stress and impaired vascular relaxation. Project 5 focuses on the microcirculation and the mechanisms that control and alter organ and tissue perfusion ..
  30. IRES-mediated translation initiation on viral mRNAs
    CHRISTOPHER ULRICH TRISTRAM HELLEN; Fiscal Year: 2013
    ..We will determine whether these mechanisms account for the relaxation on this IRES of the ribosome's normally strict avoidance of initiation at non-AUG codons...
  31. WILLIAM BRYSON CAMPBELL; Fiscal Year: 2014
    ..These studies will test the hypothesis that 11,12,15-THETA causes relaxation by inhibiting RhoA activation resulting in decreased Rho kinase activity increasing myosin light chain ..
  32. Sheila H Ridner; Fiscal Year: 2014
    ..Hatha Yoga includes basic practices of postures (asanas), breathing (pranayama), relaxation (pratyahara), and meditation (dhyana)...
  33. WILLIAM BRYSON CAMPBELL; Fiscal Year: 2015
    ..AIII is 10-fold more potent than AII in stimulating ZG cell-dependent, EET-mediated relaxation. Inhibition of AII metabolism to AIII blocks the ZG cell-mediated relaxation to AII...
  34. Molecular mechanism of regulation of mI(CAT) in intestinal smooth muscle cells
    Michael X Zhu; Fiscal Year: 2012
    ..systems, where TRPC4 and related TRPC5 channels are known to involve in functions such as vasoconstriction/relaxation, synaptic transmission, neurite outgrowth/neural development, and learning...
  35. HIGH SALT DIET, ANGIOTENSIN II, AND MICROVESSEL DILATION
    Julian H Lombard; Fiscal Year: 2012
    ..provided by applicant): High salt (HS) diet leads to a dramatic and widespread impairment of vascular relaxation mechanisms and an impaired ability to regulate tissue perfusion in the absence of an elevated blood pressure...
  36. Helene M Langevin; Fiscal Year: 2015
    ..Secondary outcome measures will be intersegmental motion during gait (in vivo), areolar PCT cell-mediated tissue relaxation (ex vivo), markers of areolar PCT neurogenic inflammation (NGF, IL1-2 and TNF-1) and spinal cord Substance P and ..
  37. Activation of PI Specific Phospholipase C Enzymes
    MARY FEDARKO ROBERTS; Fiscal Year: 2013
    ..specific nonsubstrate/allosteric phospholipid binding site(s) using high resolution field cycling 31P NMR relaxation experiments;(ii) orient these PI-PLCs on model membranes, particularly with respect to the mobile loops and ..
  38. Calcium wave propagation along microvascular endothelial tubes
    MATTHEW JOHN SOCHA; Fiscal Year: 2012
    ..initiates a Ca+2 wave that travels from EC to EC for hundreds of microns along the intima to promote relaxation of surrounding SMCs by releasing nitric oxide...
  39. Restorative Yoga for Therapy of the Metabolic Syndrome (RHYTHMS) study
    Alka M Kanaya; Fiscal Year: 2012
    ..two pilot trials of Restorative yoga, a type of yoga that uses supported poses to induce a state of total relaxation without muscular strain...
  40. Stephen J Lippard; Fiscal Year: 2016
    ..either fluorescent or phosphorescent, for use in optical imaging (OI) experiments, or capable of altering water relaxation rates, for use in magnetic resonance imaging (MRI) studies...
  41. Michael Regnier; Fiscal Year: 2015
    ..increasing [dATP] in cultured adult rat cardiomyocytes by over-expression of R1R2 enhances contraction, speeds relaxation and has no effect on intracellular Ca2+ transient amplitude but speeds it's decay...
  42. Cellular Mechanisms of Lymphatic Muscle Contractility
    MICHAEL JOHN DAVIS; Fiscal Year: 2012
    ..that the expression of these three proteins imparts the uniquely high rate of lymphatic muscle contraction/relaxation required for intrinsic pacemaker activity to be translated into efficient lymphatic pumping...
  43. HTS assay development targeting Yersinia pestis topoisomerase I
    Yuk Ching Tse-Dinh; Fiscal Year: 2011
    ..Secondary topoisomerase relaxation and cleavage activity assays are already in place...
  44. Role of Endothelin B Receptor in Vascular Protection in Females
    Raouf A Khalil; Fiscal Year: 2011
    ..An increase in the expression/activity of ETBR activates endothelium-dependent vascular relaxation pathways, and counteracts the ET- 1/ETAR-mediated vasoconstriction, and thereby provides a vascular protective ..
  45. Michael F Romero; Fiscal Year: 2015
    ..It is our premise that KATP channel activation leads to a relaxation of the trabecular meshwork resulting in increased permeability, improved fluid flow, augmented outflow facility, ..
  46. Armen Sarvazyan; Fiscal Year: 2014
    ..impulse to generate localized displacements in tissue and the resulting displacements will be tracked during relaxation using cross-correlation based methods...
  47. Exercise training improves erectile dysfunction in diabetes: role of central mech
    Kaushik P Patel; Fiscal Year: 2012
    ..Apart from peripheral actions of corporal smooth muscle relaxation, the activation of sympathetic and parasympathetic nerves involved central mechanisms are also responsible for ..
  48. Histone proline isomerization and gene regulation
    Nobuaki Kikyo; Fiscal Year: 2010
    ..and PPIA organize a specific set of epigenetic modifications on the target genes, which leads to chromatin relaxation and nuclear reprogramming. To test this hypothesis, following specific aims are proposed...
  49. Behavior Therapy for Adults with Tourette Syndrome
    Lawrence Scahill; Fiscal Year: 2009
    ..approach that includes awareness training, selfmonitoring, contingency management, inconvenience review, relaxation training and competing responses. HRT is designed as a monotherapy and/or as an augmentation to pharmacotherapy...
  50. Evaluation of an MRI Biomarker for Meniscal Repair
    Hollis G Potter; Fiscal Year: 2010
    ..of the meniscus produces limited signal intensity during standardized imaging due to short transverse relaxation times (T2)...
  51. Yulin Ge; Fiscal Year: 2016
    ..These include a recently developed T2-Relaxation-Under-Spin-Tagging (TRUST) for the evaluation of global cerebral metabolic rate of oxygen (CMRO2) and a patient-..
  52. Technical Development of Quantitative Biomarkers of Fatty Liver Disease with MRI
    Scott B Reeder; Fiscal Year: 2013
    ..Other important confounding factors must also be addressed. These include: T1 relaxation, image noise, the multiple NMR spectral peaks of fat, and eddy currents...
  53. Statistical models to investigate long-distance QTL transcription regulation
    BARBARA ELIZABETH ENGELHARDT; Fiscal Year: 2011
    ..We will use Markov chain Monte Carlo and linear programming relaxation methods that have been shown to find near-optimal solutions to this type of problem...
  54. Nitrergic Neuro-smooth Muscle Transmission in the Gut
    Raj K Goyal; Fiscal Year: 2013
    ..As a neurotransmitter, NO plays a key role in peristalsis and physiological relaxation of the sphincters and thus facilitates transport of food through the gastrointestinal tract...
  55. Adiponetin and AMPK Biosensor
    John Y J Shyy; Fiscal Year: 2010
    ..e., blood pressure, NO bioavailability, aortic ring relaxation) will be investigated...
  56. Stephanie W Watts; Fiscal Year: 2015
    ..Aim 2 will dissect whether 5-HT causes direct vascular relaxation and/or reduces sympathetic nerve activity to decrease blood pressure...
  57. MEMBRANE BASIS OF VISUAL EXCITATION
    Michael F Brown; Fiscal Year: 2012
    ..Further innovation entails ultra-large scale molecular dynamics (MD) simulations and 2H NMR relaxation measurements...
  58. Endogenous Gas Molecules As Transcription Factors
    Leo E Otterbein; Fiscal Year: 2012
    ..Prize in Medicine was awarded for the discovery and characterization of nitric oxide (NO) as endothelial derived relaxation factor...
  59. Mission Reconnect: Promoting Resilience and Reintegration of Post-Deployment Vete
    Janet Kahn; Fiscal Year: 2013
    ..Mission Reconnect" is an integrated program of (1) guided mind/body stress reduction and relaxation practices, (2) contemplative practices to engender and support appreciation, empathy and forgiveness for oneself ..
  60. Christine E Seidman; Fiscal Year: 2016
    ..Impaired LV relaxation and increased myocardial collagen synthesis both precede the onset of LVH...
  61. KIRSTEEN NAIRN BROWNING; Fiscal Year: 2014
    ..The receptive relaxation reflex is a classical, vagally-mediated reflex activated upon distension of the esophagus (during swallowing, ..
  62. Nitroso/redox balance in myocardial infarction
    Joshua M Hare; Fiscal Year: 2013
    ..exerts a broad range of regulatory influences in the cardiovascular system that extend from endothelial relaxation to platelet function, myocardial contractility, Ca2+ cycling, and energy metabolism...
  63. CARL WEI CHAN TONG; Fiscal Year: 2016
    ..filament, converting stored chemical energy to force, and then detaching forms the basis for contraction and relaxation of heart. MyBPC3 inhibits cross-bridge interaction with actin...
  64. ACTIONS OF CYCLIC GMP IN SMOOTH MUSCLE
    Thomas Lincoln; Fiscal Year: 1999
    Cyclic GMP mediates vascular smooth muscle relaxation to nitric oxide and atrial natriuretic peptides...
  65. Vascular Angiotensin Type-2 Receptor in Normal and Hypertensive Pregnancy
    Raouf A Khalil; Fiscal Year: 2010
    ..and angiotensin type 2 receptor (AT2R) to induce the release of vasodilator substances and promote vascular relaxation. The objective of this proposal is to test the hypothesis that AT2R-mediated signaling is an important regulator ..
  66. THE HIGH PRESSURE ZONE OF THE DISTAL ESOPHAGUS
    Larry Miller; Fiscal Year: 2006
    ..The PI plans to define the relative motion of the CD to the intrinsic LES the relaxation and contraction of the CD in relationship to the LES, the compressive effect and forces of the CD on the distal ..
  67. K Channel Plasticity and Regulation of Vasomotor Tone
    STEPHEN T O apos ROURKE; Fiscal Year: 2010
    ..Namely, that coincident with tolerance to the nitrates, blood vessels adapt by developing a compensatory relaxation pathway...
  68. REGULATION OF CYCLIC GMP DEPENDENT PROTEIN KINASE
    MICHAEL UHLER; Fiscal Year: 1999
    ..is believed to mediate the intracellular effects of nitric oxide and atrial natriuretic factor (ANF) on the relaxation of smooth muscle...
  69. HIV PROTEASE INHIBITORS EFFECT--NENDOTHELIAL DYSFUNCTION
    Changyi Chen; Fiscal Year: 2004
    ..McClure R01) of SHIV infection will allow analysis of vessel contraction and relaxation, endothelial cell morphology and substructures...
  70. DIASTOLIC PROPERTIES OF DEVELOPING MYOCARDIUM
    Kent Thornburg; Fiscal Year: 1993
    Although much has been learned about systolic function in the fetal sheep, little is known about the relaxation and filling phases of the cardiac cycle in immature hearts...
  71. Mechanisms of the Relaxation Response in Elderly Hypertensives
    Jeffery A Dusek; Fiscal Year: 2010
    ..We have recently completed a preliminary study showing that 8-weeks of relaxation response (RR) training significantly reduced systolic blood pressure in individuals with SH...
  72. NONPHARMACOLOGIC ANALGESIA FOR INVASIVE PROCEDURES
    Elvira Lang; Fiscal Year: 2005
    ..Nonpharmacologic analgesia includes relaxation training, self-hypnosis, and imagery...