Genomes and Genes
Summary: Therapy whose basic objective is to restore the volume and composition of the body fluids to normal with respect to water-electrolyte balance. Fluids may be administered intravenously, orally, by intermittent gavage, or by hypodermoclysis.
Publications330 found, 100 shown here
- Early goal-directed therapy in the treatment of severe sepsis and septic shockE Rivers
Department of Emergency Medicine, Henry Ford Health Systems, Case Western Reserve University, Detroit, MI 48202, USA
N Engl J Med 345:1368-77. 2001..The purpose of this study was to evaluate the efficacy of early goal-directed therapy before admission to the intensive care unit...
- Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) GroupRinaldo Bellomo
Department of Intensive Care and Medicine, Austin Health, Melbourne, Australia
Crit Care 8:R204-12. 2004..Accordingly, we sought to review the available evidence, make recommendations and delineate key questions for future studies...
- Comparison of two fluid-management strategies in acute lung injuryHerbert P Wiedemann
Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic, 9500 Euclid Ave, Desk A 90, Cleveland, OH 44195, USA
N Engl J Med 354:2564-75. 2006..Optimal fluid management in patients with acute lung injury is unknown. Diuresis or fluid restriction may improve lung function but could jeopardize extrapulmonary-organ perfusion...
- Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008R Phillip Dellinger
Cooper University Hospital, Camden, NJ, USA
Crit Care Med 36:296-327. 2008..To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," published in 2004...
- Dynamic changes in arterial waveform derived variables and fluid responsiveness in mechanically ventilated patients: a systematic review of the literaturePaul E Marik
Division of Pulmonary and Critical Care Medicine PEM, Eastern Virginia Medical School, Norfolk, VA, USA
Crit Care Med 37:2642-7. 2009..Dynamic changes in systolic pressure, pulse pressure, and stroke volume in patients undergoing mechanical ventilation have emerged as useful techniques to assess volume responsiveness...
- Intraoperative oesophageal Doppler guided fluid management shortens postoperative hospital stay after major bowel surgeryH G Wakeling
Department of Anaesthesia, Worthing Hospital, Lyndhurst Road, Worthing BN11 2DH, UK
Br J Anaesth 95:634-42. 2005..We assessed whether using intraoperative oesophageal Doppler guided fluid management to minimize hypovolaemia would reduce postoperative hospital stay and the time before return of gut function after colorectal surgery...
- Pulmonary artery occlusion pressure and central venous pressure fail to predict ventricular filling volume, cardiac performance, or the response to volume infusion in normal subjectsAnand Kumar
Division of Cardiovascular Disease and Critical Care Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL, USA
Crit Care Med 32:691-9. 2004..Neither central venous pressure nor pulmonary artery occlusion pressure appears to be a useful predictor of ventricular preload with respect to optimizing cardiac performance...
- Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trialBirgitte Brandstrup
Clinical Unit of Preventive Medicine and Health Promotion, H S Bispebjerg University Hospital, Bispebjerg Bakke 23, DK 2400 Copenhagen NV, Denmark
Ann Surg 238:641-8. 2003..To investigate the effect of a restricted intravenous fluid regimen versus a standard regimen on complications after colorectal resection...
- Assessing fluid responsiveness in critically ill patients: False-positive pulse pressure variation is detected by Doppler echocardiographic evaluation of the right ventricleYazine Mahjoub
Medical YM, CP, AF, El, Ft, CG, HD and Surgical Intensive Care Unit EZ, Department of Anesthesia and Intensive Care, Amiens University Hospital, Amiens, France
Crit Care Med 37:2570-5. 2009..Pulse pressure variation is used to predict fluid responsiveness in mechanically ventilated patients. However, this parameter has been reported to be falsely positive, especially in patients with right ventricular dysfunction...
- Respiratory changes in aortic blood velocity as an indicator of fluid responsiveness in ventilated patients with septic shockM Feissel
, Centre Hospitalier, Belfort, France
Chest 119:867-73. 2001....
- Passive leg raising predicts fluid responsiveness in the critically illXavier Monnet
, , , , , France
Crit Care Med 34:1402-7. 2006....
- Systolic pressure variation as a guide to fluid therapy in patients with sepsis-induced hypotensionB Tavernier
Department of Anesthesia 2, University Hospital, Lille, France
Anesthesiology 89:1313-21. 1998....
- The respiratory variation in inferior vena cava diameter as a guide to fluid therapyMarc Feissel
, Centre Hospitalier de Belfort, Belfort, France
Intensive Care Med 30:1834-7. 2004..CONCLUSION: Analysis of DeltaD(IVC) is a simple and non-invasive method to detect fluid responsiveness in mechanically ventilated patients with septic shock...
- Randomized controlled trial to investigate influence of the fluid challenge on duration of hospital stay and perioperative morbidity in patients with hip fracturesR Venn
Department of Anaesthesia and Intensive Care, Worthing Hospital, W. Sussex UK
Br J Anaesth 88:65-71. 2002..fluid management with two differing methods of invasive haemodynamic monitoring to optimize intraoperative fluid therapy, in patients undergoing proximal femoral fracture repair under general anaesthesia...
- Intraoperative fluid optimization using stroke volume variation in high risk surgical patients: results of prospective randomized studyJan Benes
Department of Anesthesiology and Intensive Care, Charles University Teaching Hospital, Alej Svobody 80, Plzen 304 60, Czech Republic
Crit Care 14:R118. 2010..variation (SVV) is a good and easily obtainable predictor of fluid responsiveness, which can be used to guide fluid therapy in mechanically ventilated patients...
- The passive leg-raising maneuver cannot accurately predict fluid responsiveness in patients with intra-abdominal hypertensionYazine Mahjoub
Medical and Surgical Intensive Care Unit, Department of Anesthesia and Intensive Care, Amiens University Medical Center, Amiens, France
Crit Care Med 38:1824-9. 2010..The aim of the present study was to determine whether intra-abdominal hypertension (which impairs venous return) reduces the ability of passive leg raising to detect fluid responsiveness in critically ill ventilated patients...
- American Burn Association practice guidelines burn shock resuscitationTam N Pham
University of Washington Burn Center, Seattle, Washington 98104, USA
J Burn Care Res 29:257-66. 2008
- Prediction of fluid responsiveness in acute respiratory distress syndrome patients ventilated with low tidal volume and high positive end-expiratory pressureChung Chi Huang
Division of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, Gweishan, Taoyuan, Taiwan
Crit Care Med 36:2810-6. 2008....
- Monitoring intravascular volumes for postoperative volume therapyH Brock
General Hospital, Department of Anaesthesia and Intensive Care Medicine, Linz, Austria
Eur J Anaesthesiol 19:288-94. 2002..The feasibility of monitoring measured intravascular volumes and the cardiac filling pressures were compared to reflect the optimal volume status of postoperative patients...
- Severe hypoxemic respiratory failure: part 2--nonventilatory strategiesSuhail Raoof
Division of Pulmonary and Critical Care Medicine, New York Methodist Hospital, 506 Sixth St, Brooklyn, NY 11215, USA
Chest 137:1437-48. 2010..These interventions may be considered for use, particularly for cases of refractory severe hypoxemia, with proper appreciation of potential costs and adverse effects...
- The impact of fluid therapy on microcirculation and tissue oxygenation in hypovolemic patients: a reviewJoachim Boldt
Department of Anesthesiology and Intensive Care Medicine, Klinikum der Stadt Ludwigshafen, Bremserstr 79, 67063 Ludwigshafen, Germany
Intensive Care Med 36:1299-308. 2010..This review presents the (patho)physiological basis of hypovolemia, microcirculation, and tissue oxygenation and presents a literature review on the effects of plasma substitutes on microperfusion and oxygenation in the clinical setting...
- Comparison of three fluid solutions for resuscitation in dengue shock syndromeBridget A Wills
Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
N Engl J Med 353:877-89. 2005..Although volume replacement is recognized as the critical therapeutic intervention, World Health Organization management guidelines remain empirical rather than evidence-based...
- Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical studyMoritz Wyler von Ballmoos
Department of Intensive Care Medicine, Bern University Hospital and University of Bern Inselspital, Freiburgstrasse 10, 3010 Bern, Switzerland
Crit Care 14:R111. 2010..We aimed to assess prediction of volume responsiveness with PPV in patients with increased pulmonary artery pressure...
- Colloid administration normalizes resuscitation ratio and ameliorates "fluid creep"Amanda Lawrence
Burn Trauma ICU, Department of Surgery, University of Utah College of Medicine, Salt Lake City, Utah, USA
J Burn Care Res 31:40-7. 2010..This practice can be applied selectively as needed using predetermined algorithms...
- Arterial versus plethysmographic dynamic indices to test responsiveness for testing fluid administration in hypotensive patients: a clinical trialGiuseppe Natalini
Department of Anesthesiology, Intensive Care Medicine and Emergency Medicine, Poliambulanza Foundation Hospital, Brescia, Italy
Anesth Analg 103:1478-84. 2006..These plethysmographic indices could provide a noninvasive tool for predicting the cardiac output increase by administering fluid...
- Conservative vs restrictive individualized goal-directed fluid replacement strategy in major abdominal surgery: A prospective randomized trialEmmanuel Futier
Department of Anesthesiology and Critical Care, University Hospital of Clermont Ferrand, France
Arch Surg 145:1193-200. 2010To compare the influence of 2 volumes of fluid, integrated with goal-directed fluid therapy, on hypovolemia (a key trigger of tissue hypoperfusion) and central venous oxygen saturation (Scvo₂) and to assess their relationships with ..
- Physiological effects of hyperchloraemia and acidosisJ M Handy
Chelsea and Westminster NHS Foundation Trust, Imperial College London, 369 Fulham Road, London SW10 9NH, UK
Br J Anaesth 101:141-50. 2008..It is intended to provide an assessment of the importance of hyperchloraemic acidosis and thereby the likely benefits of balanced solutions...
- Goal-directed intraoperative fluid administration reduces length of hospital stay after major surgeryTong J Gan
Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
Anesthesiology 97:820-6. 2002..The objective of this prospective, randomized study was to assess the effect of goal-directed intraoperative fluid administration on length of postoperative hospital stay...
- How perioperative fluid balance influences postoperative outcomesDileep N Lobo
Division of Gastrointestinal Surgery, Section of Surgery, E Floor, West Block, University Hospital, Queen s Medical Centre, Nottingham NG7 2UH, UK
Best Pract Res Clin Anaesthesiol 20:439-55. 2006..Perioperative fluid therapy has a direct bearing on outcome, and prescriptions should be tailored to the needs of the patient...
- Fluid therapy for the surgical patientBirgitte Brandstrup
Surgical Department, Slagelse University Hospital, Ingemannsvej 18, DK 4200 Slagelse, Denmark
Best Pract Res Clin Anaesthesiol 20:265-83. 2006Perioperative fluid therapy is the subject of much controversy, and the results of the clinical trials investigating the effect of fluid therapy on outcome of surgery seem contradictory...
- Dynamic arterial elastance to predict arterial pressure response to volume loading in preload-dependent patientsManuel Ignacio Monge García
Servicio de Cuidados Criticos y Urgencias, Unidad de Investigación Experimental, Hospital del SAS de Jerez, Jerez de la Frontera, Spain
Crit Care 15:R15. 2011....
- The Parkland formula under fire: is the criticism justified?Jennifer Blumetti
University of Texas Southwestern, Dallas, Texas, USA
J Burn Care Res 29:180-6. 2008..The Parkland formula only represents a resuscitation "starting" point. The UOP is the important parameter...
- Respiratory pulse pressure variation fails to predict fluid responsiveness in acute respiratory distress syndromeKarim Lakhal
Service de Réanimation Médicale et Maladies Infectieuses, Hopital Bichat Claude Bernard, Assistance Publique des Hopitaux de Paris, 18 rue Henri Huchard, F 75018 Paris, France
Crit Care 15:R85. 2011..We aimed to assess ΔRESPPP in a large ARDS population...
- Influence of increased intra-abdominal pressure on fluid responsiveness predicted by pulse pressure variation and stroke volume variation in a porcine modelJochen Renner
Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig Holstein, Campus Kiel, Germany
Crit Care Med 37:650-8. 2009..Therefore, the present study was designed to evaluate whether PPV and SVV are suitable for predicting fluid responsiveness during elevated IAP...
- Safety of rapid intravenous rehydration and comparative efficacy of 3 oral rehydration solutions in the treatment of severely malnourished children with dehydrating choleraNur H Alam
Clinical Sciences Division, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
J Pediatr Gastroenterol Nutr 48:318-27. 2009..Assess the safety of rapid intravenous rehydration of severely malnourished children and compare the efficacy of 3 formulations of oral rehydration salts solutions...
- The use of theraputic plasma exchange (TPE) in the setting of refractory burn shockLucas P Neff
Wake Forest University Baptist Medical Center, Department of General Surgery, Winston Salem, NC 27157, USA
Burns 36:372-8. 2010..This study examines the physiologic effects of theraputic plasma exchange (TPE) in the setting of refractory burn shock and attempts to identify variables that correlate with the eventual need for TPE...
- Predicting increased fluid requirements during the resuscitation of thermally injured patientsLeopoldo C Cancio
US Army Institute of Surgical Research, Charleston, South Carolina, USA
J Trauma 56:404-13; discussion 413-4. 2004....
- Pulse pressure variations adjusted by alveolar driving pressure to assess fluid responsivenessFabrice Vallee
Pôle Anesthésie et Réanimation, unité de réanimation polyvalente de Purpan, GRCB 48, Universite Paul Sabatier, Toulouse, France
Intensive Care Med 35:1004-10. 2009....
- Preoperative fluid and electrolyte management with oral rehydration therapyHideki Taniguchi
Department of Anesthesiology, Kanagawa Cancer Center, 1 1 2 Nakao, Asahi ku, Yokohama, 241 0815, Japan
J Anesth 23:222-9. 2009....
- The impact of opioid administration on resuscitation volumes in thermally injured patientsLucy Wibbenmeyer
Department of Surgery, The University of Iowa Carver College of Medicine, Iowa City, UT 52246, USA
J Burn Care Res 31:48-56. 2010..Because increased fluid resuscitation has been associated with adverse consequences in other studies, further research on alternative pain control strategies in thermally injured patients is warranted...
- Preliminary results of a prospective randomized trial of restrictive versus standard fluid regime in elective open abdominal aortic aneurysm repairGeralde T McArdle
Regional Vascular Surgery Unit, Royal Victoria Hospital Belfast, Belfast Health and Social Care Trust, Belfast BT14 6AB, Northern Ireland
Ann Surg 250:28-34. 2009..We tested the hypothesis that perioperative fluid restriction would reduce complications and improve outcome after elective open AAA repair...
- 'Liberal' vs. 'restrictive' perioperative fluid therapy--a critical assessment of the evidenceM Bundgaard-Nielsen
Section of Surgical Pathophysiology, University of Copenhagen, Copenhagen, Denmark
Acta Anaesthesiol Scand 53:843-51. 2009..Several studies have assessed the effect of a 'liberal' vs. a 'restrictive' perioperative fluid regimen on post-operative outcome. The literature was reviewed in order to provide recommendations regarding perioperative fluid regimens...
- Goal-directed fluid management based on the pulse oximeter-derived pleth variability index reduces lactate levels and improves fluid managementPatrice Forget
Department of Anesthesiology, St Luc Hospital, Brussels, Belgium
Anesth Analg 111:910-4. 2010..We investigated whether displaying the variability in the pulse oximeter plethysmogram (pleth variability index; PVI) would guide intraoperative fluid management and improve circulation as assessed by lactate levels...
- Relation between respiratory variations in pulse oximetry plethysmographic waveform amplitude and arterial pulse pressure in ventilated patientsMaxime Cannesson
Service de Reanimation Medicale, Centre Hospitalier Lyon Sud, Pierre Benite, France
Crit Care 9:R562-8. 2005..We conducted a prospective study to evaluate the relationship between respiratory variation in arterial pulse pressure and respiratory variation in pulse oximetry plethysmographic (POP) waveform amplitude...
- Liberal or restrictive fluid administration in fast-track colonic surgery: a randomized, double-blind studyK Holte
Department of Surgical Gastroenterology, Hvidovre University Hospital, DK 2650 Hvidovre, Denmark
Br J Anaesth 99:500-8. 2007..Therefore, we investigated the effects of two regimens of intraoperative fluids with physiological recovery as the primary outcome measure after fast-track colonic surgery...
- Pulse pressure variations to predict fluid responsiveness: influence of tidal volumeDaniel De Backer
Department of Intensive Care, Erasme University Hospital of the Free University of Brussels, Route de Lennik 808, 1070 Brussels, Belgium
Intensive Care Med 31:517-23. 2005..To evaluate the influence of tidal volume on the capacity of pulse pressure variation (DeltaPP) to predict fluid responsiveness...
- Volumetric preload measurement by thermodilution: a comparison with transoesophageal echocardiographyC K Hofer
Institute of Anaesthesiology and Intensive Care Medicine, Triemli City Hospital, Zurich, Switzerland
Br J Anaesth 94:748-55. 2005..The aim of this study was to compare volume preload monitoring using the two different thermodilution techniques with left ventricular preload assessment by transoesophageal echocardiography (TOE)...
- Plethysmographic dynamic indices predict fluid responsiveness in septic ventilated patientsMarc Feissel
Medical Intensive Care Unit, Centre Hospitalier, Belfort, France
Intensive Care Med 33:993-9. 2007....
- Pulmonary-artery versus central venous catheter to guide treatment of acute lung injuryArthur P Wheeler
Vanderbilt University, Nashville, USA
N Engl J Med 354:2213-24. 2006..The balance between the benefits and the risks of pulmonary-artery catheters (PACs) has not been established...
- Cardiac filling pressures are not appropriate to predict hemodynamic response to volume challengeDavid Osman
Service de Reanimation Medicale, Centre Hospitalo Universitaire de Bicêtre, Assistance Publique Hopitaux de Paris, Universite Paris XI, Le Kremlin Bicetre, France
Crit Care Med 35:64-8. 2007..By analyzing a large number of volume challenges, our aim was to test the significance of the recommended target values in terms of prediction of volume responsiveness...
- Randomized clinical trial assessing the effect of Doppler-optimized fluid management on outcome after elective colorectal resectionS E Noblett
Department of Surgery, Freeman Hospital, and Department of Surgical and Reproductive Sciences, University of Newcastle upon Tyne, UK
Br J Surg 93:1069-76. 2006..039). CONCLUSION: A protocol-based fluid optimization programme using intraoperative oesophageal Doppler monitoring leads to a shorter hospital stay and decreased morbidity in patients undergoing elective colorectal resection...
- Early coagulopathy in multiple injury: an analysis from the German Trauma Registry on 8724 patientsMarc Maegele
Department of Trauma and Orthopedic Surgery, University of Witten Herdecke, Cologne Merheim Medical Center, Ostmerheimerstr 200, D 51109 Cologne, Germany
Injury 38:298-304. 2007..There is increasing evidence for acute traumatic coagulopathy occurring prior to emergency room (ER) admission but detailed information is lacking...
- Acute traumatic coagulopathyKarim Brohi
Trauma and Critical Care Unit, Royal London Hospital, United Kingdom
J Trauma 54:1127-30. 2003..Traumatic coagulopathy is thought to be caused primarily by fluid administration and hypothermia...
- Postoperative complications in gastrointestinal cancer patients: the joint role of the nutritional status and the nutritional supportFederico Bozzetti
Department of Surgery, Hospital of Prato, Piazza dell Ospedale 5, 59100 Prato, Italy
Clin Nutr 26:698-709. 2007..This study investigated the effects of nutritional support on postoperative complications, in relation with demographic and nutritional factors, intraoperative factors, type and routes of nutritional regimens...
- Liberal versus restrictive fluid management in knee arthroplasty: a randomized, double-blind studyKathrine Holte
Department of Surgical Gastroenterology, Hvidovre University Hospital, Hvidovre, Denmark
Anesth Analg 105:465-74. 2007..In this study we investigated the effects of two levels of intravascular fluid administration ("liberal" versus "restrictive") in knee arthroplasty on physiological recovery as the primary outcome variable...
- Meta-analysis of standard, restrictive and supplemental fluid administration in colorectal surgeryN N Rahbari
Department of Surgery, University of Heidelberg, Heidelberg, Germany
Br J Surg 96:331-41. 2009Optimal fluid therapy for colorectal surgery remains uncertain.
- Goal-directed haemodynamic therapy and gastrointestinal complications in major surgery: a meta-analysis of randomized controlled trialsM T Giglio
Anaesthesia and Intensive Care Unit, Department of Emergency and Organ Transplantation, University of Bari, Policlinico, Piazza G Cesare 11, 70124 Bari, Italy
Br J Anaesth 103:637-46. 2009..In patients undergoing major surgery, GDT, by maintaining an adequate systemic oxygenation, can protect organs particularly at risk of perioperative hypoperfusion and is effective in reducing GI complications...
- A comparison of stroke volume variation measured by Vigileo/FloTrac system and aortic Doppler echocardiographyMatthieu Biais
Service d anesthésie réanimation I, Hopital Pellegrin, Centre Hospitalo Universitaire de Bordeaux, 33076 Bordeaux Cedex, France
Anesth Analg 109:466-9. 2009..The goal of this study was to compare stroke volume variation (SVV) assessed from a peripheral artery with the Vigileo/FloTrac system (SVV-FloTrac) with SVV derived close to the heart by aortic Doppler (SVV-Doppler)...
- Assessing shock resuscitation strategies by oxygen debt repaymentRobert Wayne Barbee
Department of Emergency Medicine, Virginia Commonwealth University Medical Center, Richmond, VA 23298, USA
Shock 33:113-22. 2010..The model also provides an unambiguous and objective standard for quantifying the behavior of various postulated shock "markers"...
- Diabetic ketoacidosis in infants, children, and adolescents: A consensus statement from the American Diabetes AssociationJoseph Wolfsdorf
Division of Endocrinology, Children's Hospital Boston, Boston, Massachusetts, USA
Diabetes Care 29:1150-9. 2006
- Influence of systolic-pressure-variation-guided intraoperative fluid management on organ function and oxygen transportM Buettner
Department of Anaesthesiology and Intensive Care Medicine, Hospital Worms, Germany
Br J Anaesth 101:194-9. 2008..We analysed the effects of SPV-guided intraoperative fluid management on organ function and perfusion when compared with routine care...
- Abdominal compartment syndrome in the severely burned patientRichard C Hershberger
University of Texas Southwestern, Dallas, USA
J Burn Care Res 28:708-14. 2007..When the Ivy score reaches 200 ml/kg, measure bladder pressures hourly. Decompressive laparotomies should be performed in all patients with ACS if less-invasive maneuvers fail...
- Isotonic is better than hypotonic saline for intravenous rehydration of children with gastroenteritis: a prospective randomised studyK A Neville
Department of Endocrinology, Sydney Children s Hospital, Sydney, Australia
Arch Dis Child 91:226-32. 2006..To determine whether the risk of hyponatraemia in children with gastroenteritis receiving intravenous (IV) fluids is decreased by the use of 0.9% saline...
- Acute respiratory distress syndromeSusannah K Leaver
Department of Critical Care, Imperial College School of Medicine, Royal Brompton Hospital, London SW3 6NP
BMJ 335:389-94. 2007
- Hypotonic versus isotonic saline in hospitalised children: a systematic reviewK Choong
Department of Paediatrics, McMaster University, Hamilton, Ontario, Canada
Arch Dis Child 91:828-35. 2006..v.) maintenance fluids are the solutions of choice in paediatric patients have not been rigorously tested in clinical trials, and may not be appropriate for all children...
- Randomised controlled trial of intravenous maintenance fluidsMichael Yung
Paediatric Intensive Care Unit, Women s and Children s Hospital, South Australia, Australia
J Paediatr Child Health 45:9-14. 2009..However, this may cause hyponatraemia in sick and post-operative children. We studied the effect of two types of intravenous maintenance fluid and two administration rates on plasma sodium concentration in intensive care patients...
- Incidence of postoperative hyponatremia and complications in critically-ill children treated with hypotonic and normotonic solutionsAlicia K Au
Department of Pediatrics, Children s National Medical Center, Washington, DC, USA
J Pediatr 152:33-8. 2008..To determine the incidence and clinical consequences of postoperative hyponatremia in children...
- The use of isotonic fluid as maintenance therapy prevents iatrogenic hyponatremia in pediatrics: a randomized, controlled open studyP Alvarez Montañana
Pediatric Intensive Care Unit, Hospital La Fe, Valencia, Spain
Pediatr Crit Care Med 9:589-97. 2008..We primarily intend to determine whether the use of isotonic fluids prevents hyponatremia and, secondly, whether these fluids increase the incidence of adverse events...
- Home management of diarrhea among underfives in a rural community in Kenya: household perceptions and practicesDoreen M Othero
Maseno University, School of Public Health and Community Development, Private Bag, Maseno Kenya
East Afr J Public Health 5:142-6. 2008..Home management of diarrhea is one of the key household practices targeted for enhancement in the Community Integrated Management of Childhood Illness (C-IMCI) strategy...
- Perceived causes and management of diarrhoea in young children by market women in Enugu State, NigeriaH N Ene-Obong
Department of Home Science and Nutrition, University of Nigeria, Nuskka, Nigeria
J Health Popul Nutr 18:97-102. 2000..The results of the study showed the evidence of unnecessary use of drugs and ignorance about their potential adverse effects. These underscore the need for appropriate primary care education among the market women in Nigeria...
- Resuscitation from septic shock with capillary leakage: hydroxyethyl starch (130 kd), but not Ringer's solution maintains plasma volume and systemic oxygenationGernot Marx
Department of Anaesthesia, University of Liverpool, Liverpool L69 3GA, United Kingdom
Shock 21:336-41. 2004..40% +/- 14%, P < 0.05) than RS animals. In this porcine septic shock model with concomitant capillary leakage syndrome, resuscitation with HES 130 kD but not RS could maintain PV and preserve systemic hemodynamics and oxygenation...
- Fluid therapy in septic shockEmanuel P Rivers
Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, Michigan, USA
Curr Opin Crit Care 16:297-308. 2010To examine the role of fluid therapy in the pathogenesis of severe sepsis and septic shock. The type, composition, titration, management strategies and complications of fluid administration will be examined in respect to outcomes.
- Relative value of pressures and volumes in assessing fluid responsiveness after valvular and coronary artery surgeryRose Marieke B G E Breukers
Department of Intensive Care, Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
Eur J Cardiothorac Surg 35:62-8. 2009..The aim of the study was to compare VS and CAS in the value of cardiac filling pressures and volumes herein...
- Pediatric hydration therapy: historical review and a new approachAaron L Friedman
Brown Medical School, and Hasbro Children's Hospital, Providence, Rhode Island 02903, USA
Kidney Int 67:380-8. 2005
- Clinical and laboratory assessment of dehydration severity in children with acute gastroenteritisPatricia C Parkin
Division of Pediatric Medicine and the Pediatric Outcomes Research Team, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
Clin Pediatr (Phila) 49:235-9. 2010..To evaluate clinical and laboratory assessment of dehydration severity in children, 1 to 36 months, with acute gastroenteritis...
- Intraoperative fluid management--what and how much?M H Rosenthal
Department of Anesthesia, Stanford University School of Medicine, CA 94305, USA
Chest 115:106S-112S. 1999..Explanations for this fluid redistribution have included tissue trauma, endotoxemia, and proinflammatory cytokines with resultant increased capillary permeability...
- Fluid resuscitation in major burnsBiswadev Mitra
The Alfred Emergency and Trauma Centre, Prahran, Victoria 3181, Australia
ANZ J Surg 76:35-8. 2006....
- Central venous O₂ saturation and venous-to-arterial CO₂ difference as complementary tools for goal-directed therapy during high-risk surgeryEmmanuel Futier
Department of Anaesthesiology and Critical Care Medicine, Estaing Hospital, University Hospital of Clermont Ferrand, 1 Place Lucie Aubrac, Clermont Ferrand, 63000, France
Crit Care 14:R193. 2010..a global index of tissue perfusion, could be used as a complementary tool to ScvO2 for goal-directed fluid therapy (GDT) to identify persistent low flow after optimization of preload has been achieved by fluid loading during ..
- Assessing fluid responses after coronary surgery: role of mathematical coupling of global end-diastolic volume to cardiac output measured by transpulmonary thermodilutionRose Marieke B G E Breukers
Department of Intensive Care and Institute for Cardiovascular Research, The Netherlands
Eur J Anaesthesiol 26:954-60. 2009....
- Intravenous rehydration for gastroenteritis: how long does it really take?Brenda J Bender
Department of Pediatrics, Albert Einstein College of Medicine, Children s Hospital at Montefiore, Bronx, NY 10467, USA
Pediatr Emerg Care 20:215-8. 2004..Studies suggest that a major barrier is a perception that the time requirement for oral rehydration therapy is too long relative to intravenous (IV) hydration...
- Trends in burn resuscitation: shifting the focus from fluids to adequate endpoint monitoring, edema control, and adjuvant therapiesKarla S Ahrns
University of Michigan Trauma Burn Center, 1500 East Medical Center Drive, Room UH1C340, Ann Arbor, MI 48109, USA
Crit Care Nurs Clin North Am 16:75-98. 2004..Future technologies targeted at microcirculatory perfusion and cellular oxygenation offer an exciting promise for less invasive, easily accessible, more accurate endpoints and treatments for bum shock resuscitation...
- Comparison between normal saline and a polyelectrolyte solution for fluid resuscitation in severely dehydrated infants with acute diarrhoeaConceição A Jucá
Emergency Unit, Hospital Infantil Albert Sabin, Fortaleza, Brazil
Ann Trop Paediatr 25:253-60. 2005..The optimal intravenous solution for rehydration of infants and children with severe dehydration is debated...
- Comparison of ultrarapid and rapid intravenous hydration in pediatric patients with dehydrationAlan L Nager
Department of Pediatrics, Division of Emergency and Transport Medicine, Children s Hospital Los Angeles, University of Southern California and the Keck School of Medicine, Los Angeles, CA, USA
Am J Emerg Med 28:123-9. 2010..The purpose of this study is to test the efficacy of ultrarapidly infused vs rapidly infused intravenous (IV) hydration in pediatric patients with acute gastroenteritis and moderate dehydration...
- Fluid therapy for children: facts, fashions and questionsMalcolm A Holliday
Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143, USA
Arch Dis Child 92:546-50. 2007b>Fluid therapy restores circulation by expanding extracellular fluid...
- Burn wound infectionsDeirdre Church
Calgary Laboratory Services, 9 3535 Research Rd N W, Calgary, Alberta, Canada T2L 2K8
Clin Microbiol Rev 19:403-34. 2006..Improved outcomes for severely burned patients have been attributed to medical advances in fluid resuscitation, nutritional support, pulmonary and burn wound care, and infection control practices...
- The treatment of pediatric gastroenteritis: a comparative analysis of pediatric emergency physicians' practice patternsStephen B Freedman
Division of Pediatric Emergency Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Acad Emerg Med 18:38-45. 2011..This study sought to describe the ED treatments administered to children with acute gastroenteritis and to compare management between Canadian and U.S. physicians practicing pediatric emergency medicine (PEM)...
- Stroke volume variation during hemorrhage and after fluid loading: impact of different tidal volumesJ Renner
Departments of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig Holstein, Campus Kiel, Schwanenweg 21, D 24105 Kiel, Germany
Acta Anaesthesiol Scand 51:538-44. 2007..This study was designed to evaluate whether the predictive value of SVV depends on the tidal volume applied particularly during acute changes of preload...
- Intravenous dextrose during outpatient rehydration in pediatric gastroenteritisJason A Levy
Division of Emergency Medicine, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
Acad Emerg Med 14:324-30. 2007..Rapid intravenous (IV) rehydration in the emergency department (ED) is required for certain children with acute gastroenteritis (AGE)...
- Accelerated intravenous rehydrationUsama Kanaan
Department of Pediatrics, Rainbow Babies and Children's Hospital and Case Western Reserve University, Cleveland, OH 44106, USA
Clin Pediatr (Phila) 42:421-6. 2003..v. fluid therapy or length of hospital stay, we conducted a retrospective cohort study utilizing chart review...
- External validation of the clinical dehydration scale for children with acute gastroenteritisBenoit Bailey
Division of Emergency Medicine, Department of Pediatrics, CHU Sainte Justine, Montreal, Quebec, Canada
Acad Emerg Med 17:583-8. 2010..The objective was to validate the clinical dehydration scale (CDS) for children with gastroenteritis in a different pediatric emergency department (ED) from where it was initially derived and validated...
- Resuscitation from hemorrhagic shock: experimental model comparing normal saline, dextran, and hypertonic saline solutionsOsvaldo Chiara
Dipartimento Scienze Chirurgiche, Universita delgi Studi di Milano, IRCCS Ospedale Maggiore, Italy
Crit Care Med 31:1915-22. 2003..To compare the effectiveness of normal saline, dextran, hypertonic, and hypertonic-hyperoncotic solutions in hemorrhagic shock...
- Treatment of calf diarrhea: intravenous fluid therapyJoachim Berchtold
Veterinary Practice, Drs Prechtl and Berchtold, Haiming 4, 83119 Obing, Germany
Vet Clin North Am Food Anim Pract 25:73-99, vi. 2009..Intravenous fluid therapy is also indicated for sick calves without obvious dehydration, such as calves with strong ion acidosis, ..
- A randomized clinical trial comparing oral ondansetron with placebo in children with vomiting from acute gastroenteritisChris Ramsook
Section of Pediatric Emergency Medicine, Wendy Fitzwilliam Pediatric Hospital, Eric Williams Medical Sciences Complex, Mt. Hope, Trinidad, West Indies
Ann Emerg Med 39:397-403. 2002..A lower proportion of patients receiving ondansetron compared with placebo required intravenous fluid therapy (P =.015). The admission rate was also lower in patients receiving ondansetron (P =.007)...
- Probing the limits of arterial pulse contour analysis to predict preload responsivenessMichael R Pinsky
Anesth Analg 96:1245-7. 2003
- Oral ondansetron for gastroenteritis in a pediatric emergency departmentStephen B Freedman
Division of Pediatric Emergency Medicine, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
N Engl J Med 354:1698-705. 2006..We conducted a double-blind trial to determine whether a single oral dose of ondansetron, an antiemetic, would improve outcomes in children with gastroenteritis...
- Normal saline versus lactated Ringer's solution for intraoperative fluid management in patients undergoing abdominal aortic aneurysm repair: an outcome studyJ H Waters
Department of General Anesthesiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Anesth Analg 93:817-22. 2001..These changes should be considered when choosing fluids for surgical procedures involving extensive blood loss and requiring extensive fluid administration...
- Influence of tidal volume on left ventricular stroke volume variation measured by pulse contour analysis in mechanically ventilated patientsDaniel A Reuter
Department of Anesthesiology, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
Intensive Care Med 29:476-80. 2003..CONCLUSIONS: In addition to intravascular volume status SVV is affected by the depth of tidal volume under mechanical ventilation. This influence must be regarded when using SVV for functional preload monitoring...
- Colloid or crystalloid for resuscitation of major burnsS J Hemington-Gorse
Plastic Surgery, Countess of Chester Hospital, Chester, UK
J Wound Care 14:256-8. 2005..This article reviews fluids used in burn resuscitation and discusses potential advantages and disadvantages of colloid and crystalloid...
- Fluid resuscitation of trauma patients: how fast is the optimal rate?Yasuaki Mizushima
Osaka Prefectural Senshu Critical Care Medical Center, Osaka 598 0048, Japan
Am J Emerg Med 23:833-7. 2005..Moderate fluid infusion rate should be considered to allow identification of the patient's response to initial fluid resuscitation...
- [The effects of rapid and slow infusion of fluid on coagulation factors in hemorrhagic shock: an experimental dogs model]Ibrahim Ikizceli
Department of Emergency Medicine, Medicine Faculty of Erciyes University, Kayseri, Turkey
Ulus Travma Acil Cerrahi Derg 12:95-100. 2006..In this study on a canine model of deep hemorrhagic shock induced by bleeding, we used various amounts of fluid infusion to determine the most appropriate amount of fluid resuscitation...
- Titrated hypertonic/hyperoncotic solution for hypotensive fluid resuscitation during uncontrolled hemorrhagic shock in ratsRainer Kentner
Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, 3434 Fifth Avenue, Pittsburgh, PA 15260, USA
Resuscitation 65:87-95. 2005..v. infusion of HHS can maintain controlled hypotension with only one-tenth of the volume of LR required, without increasing blood loss. This titrated HHS strategy may not increase the chance of long-term survival...
Research Grants108 found, 100 shown here
- Decision-Assist and Closed-Loop Fluid Resuscitation of Burn-Injured PatientsGeorge Kramer; Fiscal Year: 2009..This project will develop software and associated hardware systems to guide and perform fluid therapy in critically injured patients...
- MOLECULAR MECHANISMS OF INTESTINAL TRANSPORTErnest M Wright; Fiscal Year: 2010..Furthermore, our unexpected finding that the glucose and neurotransmitter transporters share a common structure has broad implications for transporters expressed in the enteric and central nervous systems. ..
- MOLECULAR MECHANISMS OF INTESTINAL TRANSPORTERNEST WRIGHT; Fiscal Year: 2009..Furthermore, our unexpected finding that the glucose and neurotransmitter transporters share a common structure has broad implications for transporters expressed in the enteric and central nervous systems. ..
- Probiotics in Pediatric Diarrhea in PeruRichard Oberhelman; Fiscal Year: 2007....
- LONG-TERM IMPACT AND INTERVENTION FOR DIARRHEA IN BRAZILRichard Guerrant; Fiscal Year: 2006..abstract_text> ..
- Microvascular Barrier Dysfunction in Thermal InjurySarah Y Yuan; Fiscal Year: 2010..Intensive fluid therapy is necessary for maintaining circulatory stability during the initial resuscitation period;however, without ..
- Microvascular Barrier Dysfunction in Thermal InjurySarah Yuan; Fiscal Year: 2009..Intensive fluid therapy is necessary for maintaining circulatory stability during the initial resuscitation period; however, without ..
- PROBIOTICS IN PEDIATRIC DIARRHEA IN PERU: PLANNING GRANTRichard Oberhelman; Fiscal Year: 2006..Support for these activities during a planning period before the clinical trial will greatly facilitate the implementation of the trial. ..
- Fluid Therapy and Cerebral Injury in Pediatric Diabetic KetoacidosisNATHAN contact KUPPERMANN; Fiscal Year: 2010..The relationship of fluid therapy for DKA and risk of cerebral injury and cerebral edema is not well understood and has been debated for decades...
- Decision-Assist and Closed-Loop Fluid Resuscitation of Burn-Injured PatientsGeorge C Kramer; Fiscal Year: 2010..This project will develop software and associated hardware systems to guide and perform fluid therapy in critically injured patients...
- Vibrio Cholerae as a bioterror agent: New means of treating a potential pandemicAnjaparavanda Naren; Fiscal Year: 2007..cholerae or due to natural causes. ..
- MOLECULAR MECHANISMS OF INTESTINAL TRANSPORTERNEST WRIGHT; Fiscal Year: 2007..The impact of the work ranges from a molecular understanding of oral rehydration therapy to how large class of membrane transport proteins work. ..
- MOLECULAR ARCHITECTURE OF THE NA+/GLUCOSE COTRANSPORTERERNEST WRIGHT; Fiscal Year: 2005..coli, purified and reconstituted into liposomes. The results will provide a direct test of the alternating access model for sodium/sugar cotransport. ..
- CLINICAL RESEARCH ENHANCEMENT FROM SUPPLEMENTAL TRAININGRavindra Mehta; Fiscal Year: 2007..IOur goal is to ensure that scholars emerging from this program will have the fundamental skills Inecessary for independent clinical research. ..
- PREDICTING AND IMPROVING OUTCOMES IN ACUTE RENAL FAILURERavindra Mehta; Fiscal Year: 2001..It is anticipated (by the applicants) that information gained from this study, being largely observational, will be used to rationally design intervention strategies in future years. ..
- Hypertonic Modulation of Inflammation following InjuryEileen M Bulger; Fiscal Year: 2010..The results of these studies will provide valuable information to determine the ultimate therapeutic use of the resuscitation strategy. ..
- Protocolized Goal-directed Resuscitation of Septic Shock to Prevent AKI (ProGReSSJohn A Kellum; Fiscal Year: 2010....
- Biological Markers of Recovery for the KidneyJohn Kellum; Fiscal Year: 2007..For analyses requiring serial samples and urine samples, we propose to study a subset of trial patients enrolled at 5 sites who consent to additional sample collection (208 patients) ..
- Systems Engineering of Pheresis Intervention for SepsisJohn Kellum; Fiscal Year: 2007..We will also call on the expertise of two companies, one specializing in adsorbent polymer technology (MedaSorb Technologies, LLC) and the other in complex systems modeling (Immunetrics, Inc.). ..
- Systems Engineering of Pheresis Intervention for SepsisJohn Kellum; Fiscal Year: 2009..We will also call on the expertise of two companies, one specializing in adsorbent polymer technology (MedaSorb Technologies, LLC) and the other in complex systems modeling (Immunetrics, Inc.). ..
- Cerebral edema in pediatric ketoacidosisNicole Glaser; Fiscal Year: 2009..This initial animal data will form the basis for a randomized clinical trial of interventions for the prevention of CE in children with DKA which will be the main focus of the study. ..
- Acute Renal Failure Mediated Lung InjurySarah Faubel; Fiscal Year: 2009....
- Novel treatments for polycystic kidney diseaseVicente Torres; Fiscal Year: 2009..abstract_text> ..
- Changing Cafeteria Portion Sizes to Prevent Weight GainStella Volpe; Fiscal Year: 2003..Thus, our next step would be to work with larger communities to focus on altering portion sizes in cafeterias, and even restaurants that do not offer "all you can eat" options. ..
- Supplemental Fluid & Collagen DepositionNancy Stotts; Fiscal Year: 2005..Significance: Findings from the study have the potential to significantly change how fluid is managed in nursing home residents and to lay the foundation for a major intervention study on pressure ulcer healing. ..
- KIDNEY DISEASE RESEARCH TRAINING PROGRAMVicente Torres; Fiscal Year: 2007..abstract_text> ..
- Immunological Basis of Egg AllergyAnna Nowak Wegrzyn; Fiscal Year: 2007..Intestinal permeability will also be measured at 3 and 12 months, and correlated with oral egg challenge outcome, fecal and serum anti-egg IgE and anti-egg IgG antibody levels. ..