computer assisted surgery

Summary

Summary: Surgical procedures conducted with the aid of computers. This is most frequently used in orthopedic and laparoscopic surgery for implant placement and instrument guidance. Image-guided surgery interactively combines prior CT scans or MRI images with real-time video.

Top Publications

  1. ncbi Computer-assisted knee arthroplasty versus a conventional jig-based technique. A randomised, prospective trial
    S K Chauhan
    Royal Perth Hospital, Perth, Western Australia
    J Bone Joint Surg Br 86:372-7. 2004
  2. ncbi Preoperative localization and radioguided parathyroid surgery
    Giuliano Mariani
    Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy
    J Nucl Med 44:1443-58. 2003
  3. ncbi Leg axis after computer-navigated total knee arthroplasty: a prospective randomized trial comparing computer-navigated and manual implantation
    Ralf Decking
    Department of Orthopaedic Surgery, University of Ulm, RKU, 89081 Ulm, Germany
    J Arthroplasty 20:282-8. 2005
  4. ncbi Randomized control trial comparing radiographic total knee arthroplasty implant placement using computer navigation versus conventional technique
    Pak Lin Chin
    Department of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore
    J Arthroplasty 20:618-26. 2005
  5. ncbi Early experiences of endoscopic procedures in general surgery assisted by a computer-enhanced surgical system
    M Hashizume
    Department of Disaster and Emergency Medicine, Graduate School of Medical Sciences, Kyushu University, 3 1 1, Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Surg Endosc 16:1187-91. 2002
  6. ncbi Imageless navigation for insertion of the acetabular component in total hip arthroplasty: is it as accurate as CT-based navigation?
    T Kalteis
    Department of Orthopaedic Surgery, University of Regensburg, Asklepios Klinikum Bad Abbach, Kaiser Karl V Allee 3, 93077 Bad Abbach, Germany
    J Bone Joint Surg Br 88:163-7. 2006
  7. ncbi Blood loss after total knee replacement: effects of computer-assisted surgery
    Y Kalairajah
    SPORTSMED SA, 32 Payneham Road, Stepney, Adelaide 5069, South Australia
    J Bone Joint Surg Br 87:1480-2. 2005
  8. ncbi Factors affecting error in integration of electroanatomic mapping with CT and MR imaging during catheter ablation of atrial fibrillation
    E Kevin Heist
    Cardiac Arrhythmia Service and Cardiac Unit, Massachusetts General Hospital, Gray 109, 55 Fruit St, Boston, MA, 02114, USA
    J Interv Card Electrophysiol 17:21-7. 2006
  9. ncbi Optimum threshold setting for a positron-sensitive probe with background rejection capability
    Seiichi Yamamoto
    Department of Electrical Engineering, Kobe City College of Technology, Japan
    Ann Nucl Med 18:251-6. 2004
  10. ncbi Learning the vagaries of computer-assisted total knee replacement
    J M Sikorski
    Hollywood Specialist Centre, Suite 8 95 Monash Avenue, Nedlands, Western Australia 6009, Australia
    J Bone Joint Surg Br 87:903-10. 2005

Research Grants

Detail Information

Publications258 found, 100 shown here

  1. ncbi Computer-assisted knee arthroplasty versus a conventional jig-based technique. A randomised, prospective trial
    S K Chauhan
    Royal Perth Hospital, Perth, Western Australia
    J Bone Joint Surg Br 86:372-7. 2004
    ..011) and femorotibial mismatch (p = 0.037). Standing alignment was also improved (p = 0.004) and blood loss was less (p = 0.0001). Computer-assisted surgery took longer with a mean increase of 13 minutes (p = 0.0001)...
  2. ncbi Preoperative localization and radioguided parathyroid surgery
    Giuliano Mariani
    Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy
    J Nucl Med 44:1443-58. 2003
    ..Specific guidelines should be followed when selecting patients for gamma-probe-guided MIP...
  3. ncbi Leg axis after computer-navigated total knee arthroplasty: a prospective randomized trial comparing computer-navigated and manual implantation
    Ralf Decking
    Department of Orthopaedic Surgery, University of Ulm, RKU, 89081 Ulm, Germany
    J Arthroplasty 20:282-8. 2005
    ..This difference was statistically significant. The femoral and tibial mechanical anteroposterior axis and the femoral and tibial sagittal tilt (slope) measured on sagittal x-rays were not significantly improved in this patient group...
  4. ncbi Randomized control trial comparing radiographic total knee arthroplasty implant placement using computer navigation versus conventional technique
    Pak Lin Chin
    Department of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore
    J Arthroplasty 20:618-26. 2005
    ..0%). In the sagittal axis, 90.0% CAS also had better outcomes compared with EM (63.3%) and IM (76.7%). Computer-navigated total knee arthroplasty helps increase accuracy and reduce "outliers" for implant placement...
  5. ncbi Early experiences of endoscopic procedures in general surgery assisted by a computer-enhanced surgical system
    M Hashizume
    Department of Disaster and Emergency Medicine, Graduate School of Medical Sciences, Kyushu University, 3 1 1, Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Surg Endosc 16:1187-91. 2002
    ....
  6. ncbi Imageless navigation for insertion of the acetabular component in total hip arthroplasty: is it as accurate as CT-based navigation?
    T Kalteis
    Department of Orthopaedic Surgery, University of Regensburg, Asklepios Klinikum Bad Abbach, Kaiser Karl V Allee 3, 93077 Bad Abbach, Germany
    J Bone Joint Surg Br 88:163-7. 2006
    ..001). The duration of the operation was increased by eight minutes with imageless and by 17 minutes with CT-based navigation. Imageless navigation proved as reliable as that using CT in positioning the acetabular component...
  7. ncbi Blood loss after total knee replacement: effects of computer-assisted surgery
    Y Kalairajah
    SPORTSMED SA, 32 Payneham Road, Stepney, Adelaide 5069, South Australia
    J Bone Joint Surg Br 87:1480-2. 2005
    ..This allows the ordering of less blood before the operation, reduces risks at transfusion and gives financial saving. Computer-assisted surgery may also be useful for patients in whom blood products are not acceptable...
  8. ncbi Factors affecting error in integration of electroanatomic mapping with CT and MR imaging during catheter ablation of atrial fibrillation
    E Kevin Heist
    Cardiac Arrhythmia Service and Cardiac Unit, Massachusetts General Hospital, Gray 109, 55 Fruit St, Boston, MA, 02114, USA
    J Interv Card Electrophysiol 17:21-7. 2006
    ..We sought to examine the effect of patient- and technique-related factors on integration accuracy of electroanatomic mapping with CT and MR imaging of the left atrium...
  9. ncbi Optimum threshold setting for a positron-sensitive probe with background rejection capability
    Seiichi Yamamoto
    Department of Electrical Engineering, Kobe City College of Technology, Japan
    Ann Nucl Med 18:251-6. 2004
    ..3 of the peak level of the pulse for the plastic scintillator and 0.7 of that for the BGO. With these threshold levels, the background counts could be decreased to less than 0.2% of the true positron counts...
  10. ncbi Learning the vagaries of computer-assisted total knee replacement
    J M Sikorski
    Hollywood Specialist Centre, Suite 8 95 Monash Avenue, Nedlands, Western Australia 6009, Australia
    J Bone Joint Surg Br 87:903-10. 2005
  11. ncbi A prospective, randomized study of computer-assisted and conventional total knee arthroplasty. Three-dimensional evaluation of implant alignment and rotation
    Georg Matziolis
    Center for Musculoskeletal Surgery, Charite University Medicine Berlin, Chariteplatz 1, D 10117 Berlin, Germany
    J Bone Joint Surg Am 89:236-43. 2007
    ..The objective of this study was to determine whether computer-assisted total knee arthroplasty is superior to the conventional surgical method with regard to the precision of implant positioning...
  12. ncbi Alignment in total knee arthroplasty. A comparison of computer-assisted surgery with the conventional technique
    H Bathis
    Department of Orthopaedic Surgery, University of Regensburg, Germany
    J Bone Joint Surg Br 86:682-7. 2004
    ..Potential benefits in the long-term outcome and functional improvement require further investigation...
  13. ncbi Validation and usefulness of a computer-assisted cup-positioning system in total hip arthroplasty. A prospective, randomized, controlled study
    Sebastien Parratte
    Department of Orthopedic Surgery, Aix Marseille University, Hopital Sainte Marguerite, Marseille, France
    J Bone Joint Surg Am 89:494-9. 2007
    ..The purpose of this study was to compare computer-assisted with freehand insertion of the acetabular component...
  14. ncbi Accuracy and potential pitfalls of fluoroscopy-guided acetabular cup placement
    Moritz Tannast
    Department of Orthopaedic Surgery, Inselspital
    Comput Aided Surg 10:329-36. 2005
    ....
  15. ncbi Implementation, accuracy evaluation, and preliminary clinical trial of a CT-free navigation system for high tibial opening wedge osteotomy
    Gongli Wang
    Maurice E Mueller Research Center for Orthopaedic Surgery, University of Bern, Bern, Switzerland
    Comput Aided Surg 10:73-85. 2005
    ..All these common problems can be addressed by the use of a surgical navigation system...
  16. ncbi Imaging-guided percutaneous radiofrequency ablation of solid renal masses: techniques and outcomes of 38 treatment sessions in 32 consecutive patients
    William W Mayo-Smith
    Department of Diagnostic Imaging, Rhode Island Hospital, Brown Medical School, 593 Eddy St, Providence 02903, USA
    AJR Am J Roentgenol 180:1503-8. 2003
    ..The purpose of this study was to describe the treatment techniques and results of 38 consecutive imaging-guided percutaneous radiofrequency ablations of solid renal masses performed in 32 patients...
  17. ncbi Reliability of navigated lower limb alignment in high tibial osteotomies
    Patrick Goleski
    Orthopaedic Department, Hospital for Special Surgery, New York, NY 10021, USA
    Am J Sports Med 36:2179-86. 2008
    ....
  18. ncbi Renal mass core biopsy: accuracy and impact on clinical management
    Katherine E Maturen
    Department of Radiology, UH B1D407, University of Michigan Hospitals, Ann Arbor, MI, USA
    AJR Am J Roentgenol 188:563-70. 2007
    ..The objective of our study was to determine the accuracy of imaging-guided percutaneous renal mass biopsy and its impact on clinical management...
  19. ncbi Role of navigation in total hip arthroplasty
    Todd C Kelley
    Department of Orthopaedics, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267 0212, USA
    J Bone Joint Surg Am 91:153-8. 2009
    ....
  20. ncbi Navigated open-wedge high tibial osteotomy: advantages and disadvantages compared to the conventional technique in a cadaver study
    S Hankemeier
    Trauma Department of Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Knee Surg Sports Traumatol Arthrosc 14:917-21. 2006
    ..Future studies have to analyse the clinical effects of navigation on corrective osteotomies...
  21. ncbi Consistency of implantation of a total knee arthroplasty with a non-image-based navigation system: a case-control study of 235 cases compared with 235 conventionally implanted prostheses
    Jean Yves Jenny
    Centre de Traumatologie et d Orthopedie, Strasbourg, France
    J Arthroplasty 20:832-9. 2005
    ..In accordance with current literature, survival of the navigated implanted prostheses is expected to be longer...
  22. ncbi Mid-term results of cementless total hip replacement using a ceramic-on-ceramic bearing with and without computer navigation
    N Sugano
    Department of Medical Engineering, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita 565 0871, Osaka, Japan
    J Bone Joint Surg Br 89:455-60. 2007
    ..It also reduced the rate of dislocation and mechanical problems related to impingement...
  23. ncbi Percutaneous sonographically guided radiofrequency ablation of medium-sized fibroids: feasibility study
    Chiara Recaldini
    Department of Radiology, University of Insubria, Viale Borri 57, 21100 Varese, Italy
    AJR Am J Roentgenol 189:1303-6. 2007
    ..The purpose of this study was to assess the feasibility and safety of percutaneous radiofrequency ablation under sonographic guidance as a unique procedure in the management of symptomatic uterine myomas...
  24. ncbi Measurements of acetabular cup position and pelvic spatial orientation after total hip arthroplasty using computed tomography/radiography matching
    Sorin Blendea
    Institute for Computer Assisted Orthopaedic Surgery, The Western Pennsylvania Hospital, Pittsburgh, Pennsylvania, USA
    Comput Aided Surg 10:37-43. 2005
    ..The Xalign method offered reasonable accuracy for cup orientation, and allowed cup and pelvic 3D anatomic measurements at different times...
  25. ncbi Comparison of conventional versus computer-navigated acetabular component insertion
    Rolf G A Haaker
    Facharzt für Orthopädie Rheumatologie Sportmedizin, Chirotherapie, Phys Med Orthopädische Klinik, Brakel, Germany
    J Arthroplasty 22:151-9. 2007
    ..F ratio was 5.56 for inclination and 3.67 for anteversion (P < .0001). This study demonstrated substantial statistical improvement in accuracy of cup placement using CT-based navigation compared with freehand methods...
  26. ncbi Accuracy of treatment planning based on stereolithography in computer assisted surgery
    Kurt Schicho
    University Hospital of Cranio Maxillofacial and Oral Surgery, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Med Phys 33:3408-17. 2006
    ..5 mm. This study verifies that preoperative planning on SL models and intraoperative transfer of this plan with computer assisted navigation is a suitable and sufficiently reliable method for clinical applications...
  27. ncbi Are systemic emboli reduced in computer-assisted knee surgery?: A prospective, randomised, clinical trial
    Y Kalairajah
    SPORTSMED SA, 32 Payneham Road, Stepney, Adelaide 5069, South Australia
    J Bone Joint Surg Br 88:198-202. 2006
    ..0003).Our findings show that computer-assisted total knee arthroplasty, when compared with conventional jig-based surgery, significantly reduces systemic emboli as detected by transcranial Doppler ultrasonography...
  28. ncbi Navigated total knee replacement. A meta-analysis
    Kai Bauwens
    Department of Trauma and Orthopedic Surgery, Center for Clinical Research, Unfallkrankenhaus Berlin, Warener Strasse 7, 12683 Berlin, Germany
    J Bone Joint Surg Am 89:261-9. 2007
    ..Proponents of navigated knee arthroplasty stress its potential to increase the precision of component placement. We conducted a systematic review and meta-analysis to substantiate the validity and relevance of this contention...
  29. ncbi Periprosthetic femoral supracondylar fracture after total knee arthroplasty with navigation system
    Chi Huan Li
    Department of Orthopedics and Traumatology, Taipei Veterans General Hospital, and Department of Surgery, School of Medicine, National Yang Ming University, Taipei, Taiwan
    J Arthroplasty 23:304-7. 2008
    ..Intramedullary nailing of the left femur was performed under close reduction. The possible complication of pinhole fracture to total knee arthroplasty with navigation system should be kept in mind...
  30. ncbi Novel robotic catheter remote control system: feasibility and safety of transseptal puncture and endocardial catheter navigation
    Walid Saliba
    Section of Cardiac Electrophysiology and Pacing, Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Cardiovasc Electrophysiol 17:1102-5. 2006
    ..The aims of this study were to demonstrate the safety and the feasibility of the robotic catheter remote control system (CCS) in endocardial navigation in all cardiac chambers, as well as facilitation of the transseptal puncture...
  31. ncbi The impact of CT image integration into an electroanatomic mapping system on clinical outcomes of catheter ablation of atrial fibrillation
    Peter M Kistler
    Department of Cardiology, St Bartholomew s Hospital and Queen Mary College, University of London, London, UK
    J Cardiovasc Electrophysiol 17:1093-101. 2006
    ..A detailed appreciation of left atrial/pulmonary vein (LA/PV) anatomy may be important in improving the safety and success of catheter ablation (CA) for atrial fibrillation (AF)...
  32. ncbi [CT analysis of leg alignment after conventional vs. navigated knee prosthesis implantation. Initial results of a controlled, prospective and randomized study]
    M Oberst
    Klinik fur Unfall und Wiederherstellungschirurgie, Katharinenhospital, Stuttgart
    Unfallchirurg 106:941-8. 2003
    ..This article presents the first results of a controlled, prospective and randomised trial comparing navigation versus free-hand implantation in TKA with special reference to the rotation of the femoral component...
  33. ncbi [Sonography aided computer assisted surgery (SACAS) in orbital surgery]
    P U Lohnstein
    Hals Nasen Ohren Klinik, Universitatsklinikum Freiburg, 79106, Freiburg i Br
    HNO 55:778-84. 2007
    ..The application of computer assisted procedures in orbital surgery is made more difficult by the intraoperative tissue shift in intraorbital structures, since this intraoperative dislocation cannot be imaged in preoperative CT/MR datasets...
  34. pmc Radiographic and navigation measurements of TKA limb alignment do not correlate
    Mark A Yaffe
    Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Clin Orthop Relat Res 466:2736-44. 2008
    ..This technology can function as an effective tool for assessing pre- and postoperative limb alignment and relating intraoperative alignment measurements to clinical and functional outcomes...
  35. ncbi Accuracy of a computer-assisted navigation system for total knee replacement
    R P Pitto
    University of Auckland, and Department of Orthopaedics, Middlemore Hospital, 93311 Otahuhu, Auckland, New Zealand
    J Bone Joint Surg Br 88:601-5. 2006
    ..This is the first study designed to assess the accuracy of a clinically-validated navigation system. It demonstrates in vitro accuracy of the image-free navigation system in both normal and abnormal leg alignment settings...
  36. pmc Reliability of limb alignment measurement for high tibial osteotomy with a navigation system
    J Lützner
    Department of Orthopaedic Surgery, University Hospital Carl Gustav Carus, Medical Faculty of the Technical University of Dresden, Dresden, Germany
    Eur J Med Res 14:447-50. 2009
    ..This study investigates the accuracy of limb alignment measurements with a navigation system on a cadaver specimen...
  37. ncbi Closed-wedge high tibial osteotomy using computer-assisted surgery compared to the conventional technique
    D K Bae
    Department of Orthopaedic Surgery, School of Medicine Kyung Hee University, 1 Hoeki dong, Dongdaemun ku, Seoul 130 702, Korea
    J Bone Joint Surg Br 91:1164-71. 2009
    ..3 degrees vs 3.7 degrees , p = 0,012). We conclude that navigation provides reliable real-time intra-operative information, may increase accuracy, and improves the precision of a closed-wedge HTO...
  38. ncbi Initial experience in the use of integrated electroanatomic mapping with three-dimensional MR/CT images to guide catheter ablation of atrial fibrillation
    Jun Dong
    Department of Medicine, John Hopkins University School of Medicine, Baltimore, MD 21287 0409, USA
    J Cardiovasc Electrophysiol 17:459-66. 2006
    ..No prior studies have reported the use of integrated electroanatomic mapping with preacquired magnetic resonance/computed tomographic (MR/CT) images to guide catheter ablation of atrial fibrillation (AF) in a series of patients...
  39. ncbi Accuracy evaluation of direct navigation with an isocentric 3D rotational X-ray system
    Everine B van de Kraats
    Image Sciences Institute, University Medical Center Utrecht, Q0S 459, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Med Image Anal 10:113-24. 2006
    ..The individual steps in the registration procedure are explained and evaluated. The acquired navigation accuracy using this coupling is approximately one millimeter...
  40. ncbi Evaluation of different miniplates in fixation of fractured human mandible with the finite element method
    Hasan Husnu Korkmaz
    Civil Engineering Department, Engineering and Architecture Faculty, Selcuk University, Konya, Turkey
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:e1-13. 2007
    ..The results obtained from this study offer the choice of a particular plate size, thickness, design, or configuration for application and thus provide information for clinical use...
  41. pmc Positron detection for the intraoperative localisation of cancer deposits
    Morand Piert
    Department of Nuclear Medicine, Technische Universitat Munchen, Ismaningerstrasse 22, 81675 Munich, Germany
    Eur J Nucl Med Mol Imaging 34:1534-44. 2007
    ..The study investigated the feasibility of a positron-sensitive hand-held detector system for the intraoperative localisation of tumour deposits resulting from intravenous [(18)F]FDG administration...
  42. ncbi Digital correction of magnification in pelvic x rays for preoperative planning of hip joint replacements: theoretical development and clinical results of a new protocol
    B The
    Department of Orthopedic Surgery, University Medical Center Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands
    Med Phys 32:2580-9. 2005
    ..Future research might clarify if a strict calibration protocol, as presented in this study, results in more accurate preoperative planning of hip joint replacements...
  43. ncbi Two-year outcomes of computed tomography-based and computed tomography free navigation for total knee arthroplasties
    Arno Martin
    Department of Orthopedic Surgery, Academic Teaching Hospital, Medical University of Innsbruck, Feldkirch, Austria
    Clin Orthop Relat Res 449:275-82. 2006
    ..The computed tomography-based approach has a good pre-operative planning procedure, but is more expensive and time consuming...
  44. ncbi Total hip arthroplasty through a minimal posterior approach using imageless computer-assisted hip navigation
    Richard L Wixson
    Department of Orthopaedics, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611 2983, USA
    J Arthroplasty 20:51-6. 2005
    ..The use of a computer-assisted surgery navigation system with a minimal posterior incision for a total hip arthroplasty results in significantly more reproducible acetabular component placement...
  45. ncbi Focused ultrasound surgery of intramural leiomyomas may facilitate fertility: a case report
    Miriam M F Hanstede
    Department of Obstetrics, Gynecology, and Reproductive Biology, Boston, Massachusetts, USA
    Fertil Steril 88:497.e5-7. 2007
    ..To describe a successful pregnancy after a change in configuration of the endometrial cavity after magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) for leiomyomas...
  46. pmc PET probe-guided surgery: applications and clinical protocol
    Seza A Gulec
    Center for Cancer Care at Goshen Health System, Goshen, IN, USA
    World J Surg Oncol 5:65. 2007
    ..Intraoperative localization of PET positive recurrent/metastatic lesions can be facilitated using a hand-held PET probe...
  47. pmc Influence of electrical and thermal properties on RF ablation of breast cancer: is the tumour preferentially heated?
    Vilhelm Ekstrand
    Department of Surgical Sciences, Karolinska Institutet, Stockholm, Sweden
    Biomed Eng Online 4:41. 2005
    ..The object of this study was to investigate if this preferential heating existed during experimental in vitro protocols and during computer simulations...
  48. ncbi [Implantation of a non-cemented acetabulum with the use of a navigation system]
    V Stipcák
    Ortopedické oddĕlení Nemocnice Znojmo
    Acta Chir Orthop Traumatol Cech 71:288-91. 2004
    ..To compare, on the basis of clinical and radiographic findings, the results of non-cemented acetabulum implantation involving the use of a CT-free navigation system with those of implantation without its use...
  49. ncbi An intra-operative positron probe with background rejection capability for FDG-guided surgery
    Seiichi Yamamoto
    Department of Electrical Engineering, Kobe City College of Technology, Japan
    Ann Nucl Med 19:23-8. 2005
    ..These results indicate that our developed intra-operative positron probe is valuable for radio-guided surgery on tumors using F-18-FDG in a high flux of background annihilation gamma photons...
  50. ncbi Modeling for radio-frequency conductive keratoplasty: implications for the maximum temperature reached in the cornea
    Enrique J Berjano
    Center for Research and Innovation on Bioengineering, Valencia Polytechnic University, Camino de Vera s n, 46022 Valencia, Spain
    Physiol Meas 26:157-72. 2005
    ....
  51. ncbi Fractures associated with computer-navigated total knee arthroplasty. A report of two cases
    Ho Joong Jung
    Department of Orthopaedic Surgery, Medical Center of Chung Ang University, 224 1 Heukseok dong, Dongjak Gu, Seoul 156 755, Republic of Korea
    J Bone Joint Surg Am 89:2280-4. 2007
  52. ncbi PET probe-guided surgery
    Seza A Gulec
    Center for Cancer Care, Goshen Health System, Goshen, IN, USA
    J Surg Oncol 96:353-7. 2007
    ..Due to high-energy photon fluxes, achieving a satisfactory TBR intraoperatively is challenging and requires development of a clinically feasible PET-probe guided surgery protocol...
  53. ncbi Radio-guided surgery in neuroendocrine tumors
    Seza A Gulec
    Center for Cancer Care at Goshen Health System, Goshen, IN, USA
    J Surg Oncol 96:309-15. 2007
    ..Somatostatin analog radiopharmacy continues to evolve to include the development of more selective and higher affinity analogs and PET tracers. These changes are expected to open new venues for radio-guided surgery technology...
  54. ncbi Image-guided sinus surgery: practical considerations
    Ralph Metson
    Department of Otology and Laryngology Harvard Medical School, Boston, MA 02114, USA
    Otolaryngol Clin North Am 38:527-34. 2005
    ..Surgeons who use this technology must do so with an appreciation of its potential benefits, as well as its possible pitfalls...
  55. ncbi [Computer assisted orthopedics surgery]
    E Stindel
    CHU de Brest, Service d Orthopedie, traumatologie et chirurgie réparatrice, Hopital de la Cavale Blanche, Boulevard Tanguy Prigent, 29609 Brest Cedex
    Rev Chir Orthop Reparatrice Appar Mot 93:2S11-32. 2007
    ..We will terminate this round table with a presentation of future technological advances and propose our advice for an increasingly widespread use of these new techniques...
  56. ncbi Functional impact of navigation-assisted minimally invasive total knee arthroplasty
    Jong Keun Seon
    Center for Joint Disease, Chonnam National University Hwasun Hospital, Jeonnam, Korea
    Orthopedics 28:s1251-4. 2005
    ....
  57. ncbi Process optimization in navigated total knee arthroplasty
    Tim Alexander Walde
    Nordwestkrankenhaus Sanderbusch, Sande, Germany
    Orthopedics 28:s1255-8. 2005
    ..For all patients, alignment was within 3 degrees varus/valgus postoperatively, and the mean Knee Society Score improved from 25 points preoperatively to 83 points 6 weeks postoperatively...
  58. pmc Theoretical modeling for radiofrequency ablation: state-of-the-art and challenges for the future
    Enrique J Berjano
    Center for Research and Innovation on Bioengineering, Valencia Polytechnic University, Camino de Vera s n, 46022 Valencia, Spain
    Biomed Eng Online 5:24. 2006
    ..After analyzing the current and future benefits of this technique it finally suggests future lines and trends in the research of this area...
  59. ncbi Three-dimensional rotational X-ray navigation for needle guidance in percutaneous vertebroplasty: an accuracy study
    Everine B van de Kraats
    Image Sciences Institute, University Medical Center, Utrecht, The Netherlands
    Spine (Phila Pa 1976) 31:1359-64. 2006
    ....
  60. pmc Navigation in total knee arthroplasty. A multicenter study
    F Maculé-Beneyto
    Knee Surgery Unit, Hospital Clinic, Barcelona, Spain
    Int Orthop 30:536-40. 2006
    ..001). No significant differences were found in the final angle of the extremity with the different navigation systems. The navigation systems used in this study improve the frontal angle of the arthroplasty...
  61. ncbi Computer navigation of the acetabular component: a cadaver reliability study
    J M F Spencer
    Department of Medical Engineering and Physics, Royal Perth Hospital, 6 Selby Street, Shenton Park, Perth 6008, Western Australia
    J Bone Joint Surg Br 88:972-5. 2006
    ..3 degrees ). The present method for registering pelvic landmarks shows significant inaccuracy, which highlights the need for improved methods of registration before this technique is considered to be safe...
  62. ncbi Accuracy of acetabular component positioning with a fluoroscopically referenced CAOS system
    James B Stiehl
    Department of Orthopaedic Surgery, Medical College of Wisconsin, Columbia St Mary s Hospital, Milwaukee, Wisconsin, USA
    Comput Aided Surg 10:321-7. 2005
    ..This study evaluated the accuracy, repeatability, and reproducibility of a fluoroscopic referenced system used for guiding acetabular component positioning...
  63. ncbi Femoral stress fracture after computer navigated total knee arthroplasty
    Christian Ossendorf
    Balgrist University Hospital, Department of Orthopedics, University of Zurich Forchstr 340, 8008 Zurich, Switzerland
    Knee 13:397-9. 2006
    ..However, every new technique is associated with its own complications. Here, we report on a patient who developed a distal femoral stress fracture after two attempts at fixing the navigation tracker...
  64. ncbi [Optimization of cup positioning in THA--comparison between conventional mechanical instrumentation and computer-assisted implanted cups by using the orthopilot navigation system]
    A Ottersbach
    Orthopädische Klinik im St Vincenz Hospital, Danziger Str 17, 33034 Brakel
    Z Orthop Ihre Grenzgeb 143:611-5. 2005
    ..The goal of the current study was to determine the accuracy of free-hand and computer-assisted cup replacement...
  65. ncbi The efficacy of computer assisted surgery in the endoscopic management of cerebrospinal fluid rhinorrhea
    Abtin Tabaee
    Department of Otorhinolaryngology Head and Neck Surgery, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, NY, USA
    Otolaryngol Head Neck Surg 133:936-43. 2005
    To determine the outcome of endoscopic repair of cerebrospinal fluid (CSF) rhinorrhea with and without computer assisted surgery.
  66. ncbi The role of a positron- and high-energy gamma photon probe in intraoperative localization of recurrent melanoma
    Benjamin L Franc
    Department of Radiology, University of California San Francisco, San Francisco, CA 94143 0252, USA
    Clin Nucl Med 30:787-91. 2005
    ....
  67. ncbi Nationwide survey on the use of image-guided functional endoscopic sinus surgery
    Edward J Hepworth
    Associates of Otolaryngology, P C, 950 E Harvard Avenue, Denver, CO 80210, USA
    Otolaryngol Head Neck Surg 135:68-73. 2006
    ..To evaluate impressions and usage of sinus surgery image-guided surgical (IGS) systems by ENT surgeons in the United States...
  68. ncbi How does soft tissue distribution affect anteversion accuracy of the palpation procedure in image-free acetabular cup navigation? An ultrasonographic assessment
    Jens A Richolt
    Orthopaedic University Clinic, Friedrichsheim Foundation, Marienburgstrasse 2, D 60528 Frankfurt am Main, Germany
    Comput Aided Surg 10:87-92. 2005
    ..In comparison with these permitted +/- 10 degrees windows, the amount of misinterpretation that was found due to uneven soft tissue distribution seems to be acceptable...
  69. ncbi [The history and development of computer assisted orthopaedic surgery]
    J Y Jenny
    Centre de Traumatologie et d Orthopedie, 10 avenue Baumann, F 67400, Illkirch, Fankreich
    Orthopade 35:1038-42. 2006
    ..Currently, several applications for computer assisted surgery are available...
  70. ncbi Orientation of the acetabular component. A comparison of five navigation systems with conventional surgical technique
    M Honl
    Department of Orthopaedic Surgery, LKH Klagenfurt, A 9020 Klagenfurt, St Veiter Strasse 47, Carinthia, Austria
    J Bone Joint Surg Br 88:1401-5. 2006
    ..966). The use of computer navigation helps a surgeon to orientate the acetabular component with less variation regarding inclination and anteversion...
  71. ncbi Radiofrequency ablation of hepatic tumors: simulation, planning, and contribution of virtual reality and haptics
    Caroline Villard
    LSIIT, Boulevard Sebastien Brant, Illkirch, F67400, France
    Comput Methods Biomech Biomed Engin 8:215-27. 2005
    ..We also studied how the use of virtual reality and haptic devices are valuable to make simulation and training realistic and effective...
  72. pmc Experiences with computer navigated total knee arthroplasty
    Zoltán Bejek
    Department of Orthopedics, Semmelweis University Budapest, Karolina u 27, Budapest, Hungary
    Int Orthop 31:617-22. 2007
    ..The decision is in the hands of the doctor during the entire procedure. The real benefits of the computer navigated technique require further research and can be determined only after long-term analyses...
  73. ncbi Preliminary radiological evaluation of the Vector Vision CT-free knee module for implantation of the LCS knee prosthesis
    M H A Malik
    Arrowe Park Hospital, Wirral NHS Trust, Upton, Wirral CH49 5PE, United Kingdom
    Knee 14:19-21. 2007
    We have assessed the bone cuts achieved at surgery as compared to the planned cuts produced during computer assisted surgery (CAS) using a CT-free navigation system...
  74. ncbi [Radiologic evaluation of cup placement variation in conventional total hip arthroplasty]
    U Leichtle
    Orthopadische Klinik, Universitätsklinik Tübingen
    Rofo 179:46-52. 2007
    ..Determination of the amount of variation in conventional acetabular cup positioning (radiological inclination and anteversion) in view of different factors that could influence the measured angles...
  75. ncbi Robotic technology in surgery: past, present, and future
    David B Camarillo
    Department of Mechanical Engineering, Stanford University, Stanford, California, USA
    Am J Surg 188:2S-15S. 2004
    ..Such advances will enable continued progress in surgical instrumentation and, ultimately, surgical care...
  76. ncbi Initial experience with the four-arm computer-enhanced telesurgery device in foregut surgery
    Matthew E Newlin
    Department of Surgery and Center for Minimally Invasive Surgery, Ohio State University School of Medicine and Public Health, Columbus, 43210, USA
    J Laparoendosc Adv Surg Tech A 14:121-4. 2004
    ..In this report, we describe our experience with the da Vinci robot with a fourth arm modification for the performance of selected surgical procedures...
  77. pmc The accuracy of free-hand cup positioning--a CT based measurement of cup placement in 105 total hip arthroplasties
    G Saxler
    Department of Orthopaedic Surgery, University of Duisburg Essen, Hufelandstrasse 55, 45122, Germany
    Int Orthop 28:198-201. 2004
    ..and found that only 27/105 cups were implanted within the limits of the safe position. We conclude that a safe position as defined by Lewinnek et al. [13] was only achieved in a minority of the cups that were implanted freehand...
  78. pmc Greater accuracy in positioning of the acetabular cup by using an image-free navigation system
    T Kalteis
    Department of Orthopaedic Surgery, University of Regensburg, Bad Abbach, Germany
    Int Orthop 29:272-6. 2005
    ..001 each). While only 11/22 of the cups in the control group were within the Lewinnek safe zone, 21/23 of the cups in the study group were placed in this target region (p=0.003)...
  79. ncbi Thermal-electrical modeling for epicardial atrial radiofrequency ablation
    Enrique J Berjano
    Departamento de Ingenieria Electronica, Universidad Politécnica de Valencia Camino de Vera s n, Valencia, Spain
    IEEE Trans Biomed Eng 51:1348-57. 2004
    ..It was also proved that the presence of a fat layer between the electrode and the atrial tissue decreased significantly the lesion dimensions...
  80. ncbi Three-dimensional computer-aided endoscopic sinus surgery
    F J Uddin
    Department of Otorhinolaryngology, Head and Neck Surgery, Queen s Medical Centre, Nottingham, UK
    J Laryngol Otol 117:333-9. 2003
    ..It can augment the learning curve and enhance teaching and training in endoscopic sinus surgery but it is not a substitute for a thorough knowledge of paranasal sinus anatomy...
  81. ncbi Computer-assisted orthopaedic surgery: do we need CAOS?
    J M Sikorski
    Hollywood Private Hospital, Nedlands, Western Australia
    J Bone Joint Surg Br 85:319-23. 2003
  82. ncbi Mini-incision technique for total hip arthroplasty with navigation
    Anthony M DiGioia
    Institute for Computer Assisted Orthopaedic Surgery, The Western Pennsylvania Hospital, Pittsburgh, Pennsylvania 15242, USA
    J Arthroplasty 18:123-8. 2003
    ..05), distance walked (P<.001), and stairs (P < 0.001). There was no significant difference between groups for pain, function, or range of motion at the 1-year follow-up examination...
  83. ncbi Reduction in variability of acetabular cup abduction using computer assisted surgery: a prospective and randomized study
    T Leenders
    Department of Orthopaedic Surgery, University Hospital of Antwerp, Belgium
    Comput Aided Surg 7:99-106. 2002
    ..to position the cup, although these procedures were performed in the period after we had begun using the Computer Assisted Surgery (CAS) system. The variability in cup abduction angle was assessed in all three groups and compared...
  84. ncbi Evaluation of component positioning in primary total hip arthroplasty using an imageless navigation device compared with traditional methods
    Brian C Najarian
    Department of Orthopaedic Surgery Wayne State University School of Medicine, Detroit, Michigan, USA
    J Arthroplasty 24:15-21. 2009
    ..Navigation provided controlled, reproducible acetabular alignment; but a learning curve existed in terms of accuracy, estimated blood loss, and operating room time...
  85. pmc Radiological results of image-based and non-image-based computer-assisted total knee arthroplasty
    H Bathis
    Department of Orthopaedic Surgery, University of Regensburg, PO Box 100662, 93042 Regensburg, Germany
    Int Orthop 28:87-90. 2004
    ..No significant differences were found for varus/valgus orientation of the femoral and tibial components...
  86. ncbi Computer-assisted navigation in total knee replacement: results of an initial experience in thirty-five patients
    S David Stulberg
    Department of Orthopaedic Surgery, Northwestern University Medical School, Chicago, IL 60611, USA
    J Bone Joint Surg Am 84:90-8. 2002
  87. pmc Robotic assisted radio-frequency ablation of liver tumors--randomized patient study
    A Patriciu
    The Johns Hopkins University, Baltimore, MD 21224, USA
    Med Image Comput Comput Assist Interv 8:526-33. 2005
    ..The results of this study show that in our case robotic interventions were a very viable solution. Several treatment parameters such as radiation exposures and procedure-times were found to be significantly improved in the robotic case...
  88. ncbi Endoscopic navigation for minimally invasive suturing
    Christian Wengert
    Computer Vision Laboratory, ETH Zurich, 8092 Zurich, Switzerland
    Med Image Comput Comput Assist Interv 10:620-7. 2007
    ..Finally, a visual navigation aid can be incorporated, if a 3D surface is intraoperatively reconstructed from video or registered from preoperative imaging...
  89. ncbi [Sources of error and risks in CT based navigation]
    M Arand
    Abteilung fur Unfallchirurgie, Hand und Wiederherstellungschirurgie, Universitat Ulm, Steinhovelstrasse 9, 89075 Ulm
    Orthopade 31:378-84. 2002
    ..Further, the CT-based navigation of fractured vertebrae or unstable iliosacral joints is not safe, because dislocations between acquisition of the dataset and operation will lead to misguidance...
  90. ncbi Soft-tissue motion tracking and structure estimation for robotic assisted MIS procedures
    Danail Stoyanov
    Royal Society Wolfson Foundation Medical Image Computing Laboratory, Imperial College of Science, Technology and Medicine, London SW7 2BZ, UK
    Med Image Comput Comput Assist Interv 8:139-46. 2005
    ..The practical value of the technique is demonstrated on both a deformable phantom model with tomographically derived surface geometry and in vivo robotic assisted minimally invasive surgery (MIS) image sequences...
  91. ncbi [Stereotactic telepresence in otorhinolaryngologic surgery]
    W Freysinger
    4D Visualisierung, Klinische Abteilung für allgemeine Hals, Nasen und Ohrenerkrankungen, Klinik fur Hals, Nasen und Ohrenheilkunde, Universitat Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Osterreich
    HNO 50:424-32. 2002
    ..Thus, optimal access paths and anatomical structures such as the a. carotis interna or the n. opticus can be displayed...
  92. ncbi Virtual reality system for planning minimally invasive neurosurgery. Technical note
    Axel Thomas Stadie
    Neuosurgery Clinic, Johannes Gutenberg University, Mainz, Germany
    J Neurosurg 108:382-94. 2008
    ..The authors report on their experience with a 3D virtual reality system for planning minimally invasive neurosurgical procedures...
  93. ncbi Verification of clinical precision after computer-aided reconstruction in craniomaxillofacial surgery
    Marc Christian Metzger
    Department of Craniomaxillofacial Surgery, Albert Ludwigs University Freiburg, Freiburg, Germany
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:e1-10. 2007
    ..The aim of this study was to evaluate the accuracy of the preoperative planning and the postoperative result regarding the skeletal reconstruction...
  94. ncbi Data-fusion display system with volume rendering of intraoperatively scanned CT images
    Mitsuhiro Hayashibe
    Institute for High Dimensional Medical Imaging, Jikei Univ School of Medicine, 4 11 1, Izumihoncho, Komae shi, Tokyo 201 8601, Japan
    Med Image Comput Comput Assist Interv 8:559-66. 2005
    ..The system performance was validated in an experiment carried out in the operating room...
  95. ncbi A review of the endoscopic approach to the pituitary through the sphenoid sinus
    Marc R Rosen
    Department of Otolaryngology Head and Neck Surgery, Thomas Jefferson University, 925 Chestnut St, 6th Floor, Philadelphia, PA 19107, USA
    Curr Opin Otolaryngol Head Neck Surg 14:6-13. 2006
    ..The refinement of minimally invasive endoscopic techniques has resulted in 'pure' endoscopic endonasal trans-sphenoidal surgery, which is a new approach for the removal of pituitary tumors...
  96. ncbi Stereo display of 3D ultrasound images for surgical robot guidance
    Paul M Novotny
    Division of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA
    Conf Proc IEEE Eng Med Biol Soc 1:1509-12. 2006
    ..Results indicate that subjects were able to complete surgical tasks 35 % faster with stereo-displayed 3DUS images compared to conventional two dimensional display of 3DUS...
  97. ncbi [CRANIO--development of a system for computer- and robot-assisted craniotomy]
    P Bast
    Institut für Biomedizinische Technologien, RWTH Aachen, Deutschland
    Biomed Tech (Berl) 47:9-11. 2002
    ..In this context, work space tests were performed with a hexapod parallel robot. The milling of any contour geometry could be realized with different tool angles using the existing CRIGOS robot system without additional axes...
  98. ncbi Automatic generation of hexahedral and tetrahedral meshes
    P Zerfass
    Surgical Systems Lab, Research Center Caesar Friedensplatz 16, 53111 Bonn, Germany
    Biomed Tech (Berl) 47:79-82. 2002
    ..The software creates a pipeline to automatically construct meshed datasets for finite element modelling from presegmented patient data...
  99. ncbi Design and development of a computer assisted glenoid implantation technique for shoulder replacement surgery
    Duong Nguyen
    Bioengineering Research Laboratory, The Hand and Upper Limb Centre, St Joseph s Health Care London, London, Ontario, Canada
    Comput Aided Surg 12:152-9. 2007
    ..The objective of this study was to develop and evaluate a Computer Assisted Glenoid Implantation (CAGI) technique to achieve a more accurate and reliable placement of the glenoid component...
  100. ncbi A probabilistic framework for tracking deformable soft tissue in minimally invasive surgery
    Peter Mountney
    Department of Computing, Imperial College, London SW7 2BZ, UK
    Med Image Comput Comput Assist Interv 10:34-41. 2007
    ..The performance of the proposed method is evaluated with both simulated data with known ground truth, as well as in vivo video sequences recorded from robotic assisted MIS procedures...
  101. ncbi A new registration/visualization paradigm for CT-fluoroscopy guided RF liver ablation
    Ruxandra Micu
    Chair for Computer Aided Medical Procedures, TU Munich, Germany
    Med Image Comput Comput Assist Interv 9:882-90. 2006
    ..Experiments on synthetic and real patient data and direct feedback of two interventionalists validate our alternative approach...

Research Grants62

  1. High Intensity Ultrasound in Gastroenterology
    JOO HWANG; Fiscal Year: 2003
    ..It is anticipated that this work will help to gain a better understanding of the mechanisms of HIFU and its potential role for other GI applications such as tumor therapy. ..
  2. AAOS Multi-Year Research Symposia for 2006-2010
    Christopher H Evans; Fiscal Year: 2010
    ..Fracture Repair: Critical Issues in Furthering our Understanding (2007), Musculoskeletal Imaging and Computer Assisted Surgery (2008), Orthopaedic Randomized Clinical Trials: Opportunities and Challenges (2009), and Musculoskeletal ..
  3. AAOS/NIH Mulit-Year Research Symposia for 2005-2009
    Christopher Evans; Fiscal Year: 2005
    ..Disc Degeneration (2005), Developmental Biology and Orthopaedics (2006), Musculoskeletal Imaging and Computer Assisted Surgery (2007), Senior Sports and Aging (2008), Clinical Trials in Orthopaedics (2009)...
  4. Computer Assisted Surgery Prenatal Cardiac Intervention
    Constantinos Nikou; Fiscal Year: 2004
    ..In Phase Two, we will conduct in vivo tests of the sensors in appropriate animal models. ..
  5. Software Selective Focus for Cell Analysis
    Gregory Johnson; Fiscal Year: 2004
    ..even larger market in medical industrial and consumer applications: Surgical imaging used in remote and computer assisted surgery, Diagnostic imaging applications, e.g...
  6. A General Model of Saccadic Selectivity in Visual Search
    Marc Pomplun; Fiscal Year: 2007
    ..Moreover, the results of the study can directly be applied to improve current human-computer interfaces for computer-assisted surgery and x-ray image analysis. [unreadable] [unreadable] [unreadable]..
  7. Computer Assisted Surgery Prenatal Cardiac Intervention
    Constantinos Nikou; Fiscal Year: 2006
    ..This technology has broad applicability to other ultrasound-guided procedures in the fetus, child, and adult. ..
  8. CORE SEGMENTATION TOOLS FOR COMPUTER ASSISTED SURGERY
    Ron Kikinis; Fiscal Year: 2001
    ..The segmentation algorithms will be enhanced and expanded, and protocols will be developed to assess their reproducibility, accuracy, and precision, based on currently accepted standard comparative measures. ..
  9. CORE SEGMENTATION TOOLS FOR COMPUTER ASSISTED SURGERY
    Ron Kikinis; Fiscal Year: 2002
    ..The segmentation algorithms will be enhanced and expanded, and protocols will be developed to assess their reproducibility, accuracy, and precision, based on currently accepted standard comparative measures. ..
  10. Minimally Invasive Vertebral Tracking System for CAS
    Neil Glossop; Fiscal Year: 2002
    ..The instrumentation developed here will be offered to computer assisted surgery (CAS) vendors for incorporation into their product lines.
  11. Image-Guided Otologic Surgery
    Robert Labadie; Fiscal Year: 2004
    ..It is anticipated that this system will make ear surgery safer and more efficient. ..
  12. Robotic Mastoidectomy
    Robert Labadie; Fiscal Year: 2008
    ..It is hypothesized that this strategy will be more efficient than either the human or robotic interventions examined in Specific Aim 2. [unreadable] [unreadable] [unreadable]..
  13. OR2020 Workshop: Operating Room of the Future
    Kevin Cleary; Fiscal Year: 2004
    ..The workshop is currently scheduled to be held from April 16-17, 2004, at Turf Valley Conference Center in Ellicot City, Maryland. ..
  14. Developing computerized tools for cryosurgery planning
    Yoed Rabin; Fiscal Year: 2007
    ..Such visualization capabilities will provide surgeons with insights into the physics of cryosurgery that are difficult to obtain from physical experiments or surgical practice. [unreadable] [unreadable]..
  15. Software Toolkit for Image Guided Surgery
    Kevin Cleary; Fiscal Year: 2005
    ..Dissemination activities will be undertaken with the aim of fostering the use of the toolkit in research and clinical applications. ..
  16. Robotically Assisted Mouse Interventions
    Kevin Cleary; Fiscal Year: 2008
    ..3. Perform a feasibility study using 10 mice to demonstrate the ability of the robot to biopsy the mouse flank as selected on the MRI images and evaluate the accuracy of the system. [unreadable] [unreadable] [unreadable]..
  17. A Beta-Sensitive Probe System for Use in Endoscopy
    RAYMOND RAYLMAN; Fiscal Year: 2002
    ..abstract_text> ..
  18. CT fluoroscopy guided robotically assisted lung biopsy
    Kevin Cleary; Fiscal Year: 2005
    ..The system will be validated in phantom and animal studies. The R33 phase will result in a system that is ready for clinical trials. ..
  19. Continued Development for The Image-guided Surgical Toolkit Project (IGSTK)
    Kevin Cleary; Fiscal Year: 2009
    ....
  20. Thermo mechanical stress in cryopreserved blood vessels
    Yoed Rabin; Fiscal Year: 2006
    ..Although the experimental work in this study is targeted to blood vessels, the results of this study could be expanded and become useful for a wide variety of cryopreserved natural tissues and engineered constructs. ..
  21. High Resolution Imaging Endoscopic Probe
    Nicusor Iftimia; Fiscal Year: 2006
    ..It is evident that earlier diagnosis results in an improved outcome, decreased morbidity and reduced mortality from disease. [unreadable] [unreadable] [unreadable]..
  22. Intraoperative 3T MRI Scanner for Minimally Invasive Therapy
    Ferenc Jolesz; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  23. Haptic Feedback for Robot-Assisted Surgical Systems
    Allison Okamura; Fiscal Year: 2006
    ..abstract_text> ..
  24. In Vivo PCL Biomechanics
    Guoan Li; Fiscal Year: 2007
    ..Our image technique will be further applicable to other soft tissue injuries such as cartilage defects and soft tissue defects in the shoulder, hip, wrist, ankle and spine. ..
  25. IMAGE GUIDED THERAPY CENTER
    Ferenc Jolesz; Fiscal Year: 2009
    ..abstract_text> ..
  26. In-vivo ACL Tension
    Guoan Li; Fiscal Year: 2007
    ..This methodology can be readily extended to investigate and optimize the treatment of soft tissue injures of other articular joints such as the spine, shoulder, wrist and ankle. [unreadable] [unreadable] [unreadable]..
  27. Deformable image registration and reconstruction for radiotherapy applications
    Martin J Murphy; Fiscal Year: 2010
    ..The third aim of the project is to develop measurement and validation procedures to assess the accuracy and reliability of these novel image registration and reconstruction techniques. ..
  28. Image Overlay for MRI-Guided Needle Insertions
    JOHN ANTHONY CARRINO; Fiscal Year: 2010
    ..It can also reduce variability among practitioners, facilitate training, and serve as a research validation tool by providing precisely placed minimally invasive percutaneous conduit under MR guidance. ..
  29. Bioimage Suite: A structural, functional and metabolic image analysis platform
    Xenophon Papademetris; Fiscal Year: 2009
    ..g. diabetes, cardiovascular disease, autism, epilepsy), planning therapy (e.g. neurosurgery) and evaluating other proposed treatment procedures (e.g. new drugs) ..
  30. Machine Learning for Improved Mammography Screening
    Elizabeth S Burnside; Fiscal Year: 2010
    ....
  31. 2008 Summer Bioengineering Conference
    Baruch Lieber; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  32. Angiogenesis and Cardiac Growth as Heart Failure Therapy
    Y Woo; Fiscal Year: 2008
    ..The candidate's institution, sponsor, and chairman provide a uniquely supportive, high-caliber, educationally stimulating environment highly conducive to the achievement of these goals. ..
  33. Real-Time Monitoring of Laser Ablation with OCT
    BRIAN GOLDBERG; Fiscal Year: 2008
    ..Although our approach is applicable to a spectrum of diseases, we will specifically focus on the treatment of Barrett's esophagus. [unreadable] [unreadable] [unreadable]..
  34. Image-guided intervention system for pancreatic cancer
    Nicusor Iftimia; Fiscal Year: 2007
    ..An animal study will be performed as well to test the efficiency of laser therapy. ..
  35. Novel Cancer Targeting Mechanism for Nuclear Imaging
    Benjamin Franc; Fiscal Year: 2006
    ..In summary, the targeting strategy developed in this project aims to open the door to novel cancer targets for nuclear imaging. ..
  36. Na Channels in Afferents after Bladder Obstruction
    William Steers; Fiscal Year: 2006
    ..Insight into these cellular processes could be exploited to develop afferent based treatments for OAB employing pharmacologic, molecular or gene based strategies. ..
  37. Eliciting Truly Informed Consent
    William Hendee; Fiscal Year: 2003
    ..abstract_text> ..
  38. CEREBRAL MITOCHONDRIAL METABOLISM IN NEURODEGENERATION
    William Powers; Fiscal Year: 2004
    ..If such studies yield consistent results, they will establish the basis for the utilization of platelet rnitochondrial function assays to monitor cerebral mitochondrial metabolism. ..
  39. 3D CORONARY RECONSTRUCTION AND MULTIMODALITY FUSION
    Shiuh Yung Chen; Fiscal Year: 2003
    ..abstract_text> ..
  40. ONTOGENY OF GABAA RECEPTOR COMPLEX MEASURED WITH PET
    Otto Muzik; Fiscal Year: 2002
    ..abstract_text> ..
  41. Prostate Cancer Screening With Electrical Impedance Measurements
    Alexander Hartov; Fiscal Year: 2010
    ..We also will develop new electronics and reconstruction techniques applicable to this configuration. This project capitalizes on our group's extensive experience in impedance imaging. ..
  42. IN VIVO IMAGING OF FORMATION OF HEPATIC METASTASES
    Jonathan Kruskal; Fiscal Year: 2002
    ..This project will allow identification of a series of in vivo steps that can be used to explore novel diagnostic and therapeutic probes in animal studies. ..
  43. Cryosurgery with Electrical Impedance Tomography
    Alexander Hartov; Fiscal Year: 2001
    ..The integration of EIT capabilities with their existing equipment would constitutive a unique and possible very significant improvement in the current state of the art in cryosurgery. ..
  44. Software tools for pediatric neuroimaging
    Otto Muzik; Fiscal Year: 2004
    ..If successful, this determination will impact upon a large number of children with uncontrolled epilepsy as well as other neurological disorders. ..
  45. Transrectal Ultrasound Ablation Of The Prostate
    Gabor Fichtinger; Fiscal Year: 2004
    ..The resulting system will be tested on canine subjects and in a limited manner on human patients. The endpoint of the proposed research is a system for which IRB approval can be sought to conduct clinical trials. ..
  46. Biomechanical Modeling for Steerable Needles
    Allison Okamura; Fiscal Year: 2005
    ..A particular challenge is the development of new modeling techniques that simultaneously handle needle and tissue deformation. ..
  47. Electromagnetic Tracking of Tumors for Radiotherapy
    Martin Murphy; Fiscal Year: 2006
    ..The augmented Calypso targeting system will be designed for integration into existing radiation therapy systems to provide enhanced beam targeting capability. [unreadable] [unreadable]..
  48. Minimally Invasive Approaches for Craniofacial Surgery
    Maria Troulis; Fiscal Year: 2005
    ..abstract_text> ..
  49. Substrate Mapping & Ablation of Ventricular Tachycardia
    Vivek Reddy; Fiscal Year: 2006
    ..abstract_text> ..
  50. ROLE OF FDG-PET, 1H-MRSI, AND MSI IN EPILEPSY SURGERY
    Robert Knowlton; Fiscal Year: 2005
    ....
  51. PET Imaging of the Pancreas in Murine Models of Diabetes
    Paige Clark; Fiscal Year: 2005
    ..The method could also be useful in evaluating the function of pancreatic transplants and successful engraftment of transplanted progenitor or beta cells. ..
  52. Gene methylation in glioma and normal glial cells
    Justin Smith; Fiscal Year: 2005
    ..Furthermore, comparison of methylation patterns may: 1) identify subtype-specific markers to aid in classifying gliomas and 2) provide clues to the cells of origin of gliomas. ..
  53. Steering Flexible Needles in Soft Tissue
    ALLISON MARIKO OKAMURA; Fiscal Year: 2010
    ....
  54. RETROSPECTIVE IMAGE REGISTRATION EVALUATION
    J Fitzpatrick; Fiscal Year: 2003
    ..The objective assessment provided by this project should foster improvement of the accuracy of retrospective registration techniques. ..
  55. RETROSPECTIVE IMAGE REGISTRATION EVALUATION
    J Fitzpatrick; Fiscal Year: 2002
    ..The objective assessment provided by this project should foster improvement of the accuracy of retrospective registration techniques. ..
  56. HIGH SPEED GRADIENT DRIVER UPGRADE FOR IMRI SCANNER
    R Butts; Fiscal Year: 2001
    ..This upgrade will allow us to bring all applications into the real-time regime which is absolutely critical for interventional procedures. ..
  57. Novel Signaling Targets in GI Neuroendocrine Tumors
    Herbert Chen; Fiscal Year: 2005
    ..The possibility that raf-l-mediated hormone suppression could be induced by a soluble factor would provide a plausible, therapeutic delivery method. ..
  58. Phase II Clinical Trial Utilizing Lithium for Patients with Neuroendocrine Tumors
    Herbert Chen; Fiscal Year: 2008
    ..Besides surgery, there are limited curative and palliative treatments available to patients with metastatic NE tumors, emphasizing the need for development of other forms of therapy. [unreadable] [unreadable] [unreadable]..
  59. Signaling Pathways in Medullary Thyroid Cancer
    Herbert Chen; Fiscal Year: 2004
    ..abstract_text> ..