catheter ablation

Summary

Summary: Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias.

Top Publications

  1. ncbi Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC)
    A John Camm
    Eur Heart J 31:2369-429. 2010
  2. pmc Percutaneous radiofrequency ablation with multiple electrodes for medium-sized hepatocellular carcinomas
    Jung Lee
    Seoul National University Hospital, Seoul 110 744, Korea
    Korean J Radiol 13:34-43. 2012
  3. ncbi Updated worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation
    Riccardo Cappato
    Arrhythmias and Electrophysiology Center, IRCCS, Policlinico San Donato, Milan, Italy
    Circ Arrhythm Electrophysiol 3:32-8. 2010
  4. ncbi The use of dabigatran immediately after atrial fibrillation ablation
    Roger A Winkle
    Cardiovascular Medicine and Cardiac Arrhythmias, E Palo Alto, Sequoia Hospital, Redwood City, California, USA
    J Cardiovasc Electrophysiol 23:264-8. 2012
  5. ncbi 2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design
    Hugh Calkins
    Johns Hopkins Hospital, Baltimore, MD, USA
    J Interv Card Electrophysiol 33:171-257. 2012
  6. ncbi Feasibility and safety of dabigatran versus warfarin for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from a multicenter prospective registry
    Dhanunjaya Lakkireddy
    Division of Cardiovascular Diseases, Cardiovascular Research Institute, Mid America Cardiology, University of Kansas Hospital and Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160 7200, USA
    J Am Coll Cardiol 59:1168-74. 2012
  7. ncbi Sustained complete response and complications rates after radiofrequency ablation of very early hepatocellular carcinoma in cirrhosis: Is resection still the treatment of choice?
    Tito Livraghi
    Department of Radiology, Ospedale Civile, Vimercate, Milano, Italy
    Hepatology 47:82-9. 2008
  8. ncbi Pericardial fat is associated with atrial fibrillation severity and ablation outcome
    Christopher X Wong
    Centre for Heart Rhythm Disorders CHRD, Royal Adelaide Hospital and the University of Adelaide, Adelaide, Australia
    J Am Coll Cardiol 57:1745-51. 2011
  9. ncbi Novel advancements in the management of hepatocellular carcinoma in 2008
    Josep M Llovet
    Barcelona Clinic Liver Cancer BCLC Group, Liver Unit, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, CIBERehd, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    J Hepatol 48:S20-37. 2008
  10. ncbi HRS/EHRA/ECAS expert Consensus Statement on catheter and surgical ablation of atrial fibrillation: recommendations for personnel, policy, procedures and follow-up. A report of the Heart Rhythm Society (HRS) Task Force on catheter and surgical ablation of
    Hugh Calkins
    Johns Hopkins Hospital, Maryland, USA
    Heart Rhythm 4:816-61. 2007

Detail Information

Publications313 found, 100 shown here

  1. ncbi Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC)
    A John Camm
    Eur Heart J 31:2369-429. 2010
  2. pmc Percutaneous radiofrequency ablation with multiple electrodes for medium-sized hepatocellular carcinomas
    Jung Lee
    Seoul National University Hospital, Seoul 110 744, Korea
    Korean J Radiol 13:34-43. 2012
    ..To prospectively evaluate the safety and short-term therapeutic efficacy of switching monopolar radiofrequency ablation (RFA) with multiple electrodes to treat medium-sized (3.1-5.0 cm), hepatocellular carcinomas (HCC)...
  3. ncbi Updated worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation
    Riccardo Cappato
    Arrhythmias and Electrophysiology Center, IRCCS, Policlinico San Donato, Milan, Italy
    Circ Arrhythm Electrophysiol 3:32-8. 2010
    The purpose of this study was to provide an updated worldwide report on the methods, efficacy, and safety of catheter ablation of atrial fibrillation (AF).
  4. ncbi The use of dabigatran immediately after atrial fibrillation ablation
    Roger A Winkle
    Cardiovascular Medicine and Cardiac Arrhythmias, E Palo Alto, Sequoia Hospital, Redwood City, California, USA
    J Cardiovasc Electrophysiol 23:264-8. 2012
    ..Dabigatran is a new anticoagulant and may be useful after AF ablation to prevent thromboembolic events...
  5. ncbi 2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design
    Hugh Calkins
    Johns Hopkins Hospital, Baltimore, MD, USA
    J Interv Card Electrophysiol 33:171-257. 2012
    ..This is endorsed by the governing bodies of the ACC Foundation, the AHA, the ECAS, the EHRA, the STS, the APHRS, and the HRS...
  6. ncbi Feasibility and safety of dabigatran versus warfarin for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from a multicenter prospective registry
    Dhanunjaya Lakkireddy
    Division of Cardiovascular Diseases, Cardiovascular Research Institute, Mid America Cardiology, University of Kansas Hospital and Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160 7200, USA
    J Am Coll Cardiol 59:1168-74. 2012
    ..The purpose of this study was to evaluate the feasibility and safety of periprocedural dabigatran during atrial fibrillation (AF) ablation...
  7. ncbi Sustained complete response and complications rates after radiofrequency ablation of very early hepatocellular carcinoma in cirrhosis: Is resection still the treatment of choice?
    Tito Livraghi
    Department of Radiology, Ospedale Civile, Vimercate, Milano, Italy
    Hepatology 47:82-9. 2008
    ..Perioperative mortality, major complication, and 5-year survival rates were 0%, 1.8%, and 68.5%, respectively...
  8. ncbi Pericardial fat is associated with atrial fibrillation severity and ablation outcome
    Christopher X Wong
    Centre for Heart Rhythm Disorders CHRD, Royal Adelaide Hospital and the University of Adelaide, Adelaide, Australia
    J Am Coll Cardiol 57:1745-51. 2011
    ..The aim of this study was to characterize the relationship between pericardial fat and atrial fibrillation (AF)...
  9. ncbi Novel advancements in the management of hepatocellular carcinoma in 2008
    Josep M Llovet
    Barcelona Clinic Liver Cancer BCLC Group, Liver Unit, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, CIBERehd, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    J Hepatol 48:S20-37. 2008
    ..Now, the research effort faces other areas of unmet need, such as the adjuvant setting of resection/local ablation and combination therapies...
  10. ncbi HRS/EHRA/ECAS expert Consensus Statement on catheter and surgical ablation of atrial fibrillation: recommendations for personnel, policy, procedures and follow-up. A report of the Heart Rhythm Society (HRS) Task Force on catheter and surgical ablation of
    Hugh Calkins
    Johns Hopkins Hospital, Maryland, USA
    Heart Rhythm 4:816-61. 2007
  11. pmc A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma
    Min shan Chen
    Department of Hepatobiliary Surgery, Cancer Centre of Sun Yat sen University, Guangzhou, China
    Ann Surg 243:321-8. 2006
    ..To compare the results of percutaneous local ablative therapy (PLAT) with surgical resection in the treatment of solitary and small hepatocellular carcinoma (HCC)...
  12. ncbi Percutaneous radiofrequency ablation for hepatocellular carcinoma. An analysis of 1000 cases
    Ryosuke Tateishi
    Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    Cancer 103:1201-9. 2005
    ..Previously reported treatment efficacy and complication rates have varied considerably...
  13. ncbi ESH position paper: renal denervation - an interventional therapy of resistant hypertension
    Roland E Schmieder
    University Hospital Erlangen, Nephrology and Hypertension, Erlangen, Germany
    J Hypertens 30:837-41. 2012
    ..This position statement intends to facilitate a better understanding of the effectiveness, safety, limitations and issues still to be addressed with RDN...
  14. ncbi Acute pulmonary vein isolation is achieved by a combination of reversible and irreversible atrial injury after catheter ablation: evidence from magnetic resonance imaging
    Aruna Arujuna
    Division of Imaging Sciences and Biomedical Engineering, King s College London, London, United Kingdom
    Circ Arrhythm Electrophysiol 5:691-700. 2012
    ..We used cardiac magnetic resonance imaging after radiofrequency ablation to investigate the hypothesis that acute pulmonary vein isolation results from a combination of irreversible and reversible atrial injury...
  15. ncbi Laparoscopic radiofrequency ablation of neuroendocrine liver metastases: a 10-year experience evaluating predictors of survival
    Peter J Mazzaglia
    Rhode Island Hospital, Providence, RI, USA
    Surgery 142:10-9. 2007
    ..This study analyzes our 10-year experience and determines characteristics predictive of survival...
  16. ncbi Catheter ablation for atrial fibrillation: are results maintained at 5 years of follow-up?
    Rukshen Weerasooriya
    Hopital Cardiologique du Haut Leveque, Bordeaux Pessac, France
    J Am Coll Cardiol 57:160-6. 2011
    This study describes 5-year follow-up results of catheter ablation for atrial fibrillation (AF).
  17. ncbi A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation: the APAF Study
    Carlo Pappone
    Division of Cardiac Pacing and Electrophysiology, San Raffaele University Hospital, Milan, Italy
    J Am Coll Cardiol 48:2340-7. 2006
    ..We compared ablation strategy with antiarrhythmic drug therapy (ADT) in patients with paroxysmal atrial fibrillation (PAF)...
  18. ncbi The use of a radiofrequency needle improves the safety and efficacy of transseptal puncture for atrial fibrillation ablation
    Roger A Winkle
    Cardiovascular Medicine and Cardiac Arrhythmias, East Palo Alto, California 94303, USA
    Heart Rhythm 8:1411-5. 2011
    ..Atrial fibrillation (AF) ablation requires transseptal puncture to gain entry to the left atrium (LA). On rare occasions, LA entry cannot be achieved or cardiac perforation results in pericardial tamponade...
  19. pmc Detection and quantification of left atrial structural remodeling with delayed-enhancement magnetic resonance imaging in patients with atrial fibrillation
    Robert S Oakes
    Atrial Fibrillation Program, University of Utah School of Medicine, Salt Lake City, UT 84132 2400, USA
    Circulation 119:1758-67. 2009
    ..In this study, we report the utility of delayed-enhancement magnetic resonance imaging (DE-MRI) in detecting abnormal atrial tissue before radiofrequency ablation and in predicting procedural outcome...
  20. ncbi Prognostic implications of the high-sensitive C-reactive protein in the catheter ablation of atrial fibrillation
    Yenn Jiang Lin
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Am J Cardiol 105:495-501. 2010
    ..study investigated the association among hs-CRP, substrate properties, and long-term clinical outcomes after catheter ablation of atrial fibrillation (AF)...
  21. ncbi Associations among the CHADS(2) score, atrial substrate properties, and outcome of catheter ablation in patients with paroxysmal atrial fibrillation
    Tze Fan Chao
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Heart Rhythm 8:1155-9. 2011
    ..The CHADS₂ score (congestive heart failure, hypertension, age >75 years, diabetes, and previous stroke/transient ischemic attack) is used for the risk stratification of strokes in patients with atrial fibrillation (AF)...
  22. ncbi Outcome parameters for trials in atrial fibrillation: executive summary
    Paulus Kirchhof
    Department of Cardiology and Angiology, University Hospital Munster, Albert Schweitzer Strasse 33, D 48149 Munster, Germany
    Eur Heart J 28:2803-17. 2007
    ..In addition to a careful selection of a relevant primary outcome parameter, coverage of outcomes in all major domains of AF-related morbidity and mortality is desirable for any clinical trial in AF...
  23. ncbi Systematic review and meta-analysis of survival and disease recurrence after radiofrequency ablation for hepatocellular carcinoma
    L Tiong
    University of Adelaide Department of Surgery, Queen Elizabeth Hospital, Woodville, Adelaide, South Australia 5011, Australia
    Br J Surg 98:1210-24. 2011
    ..This review examined the survival and disease recurrence rates after RFA for HCC over the past decade...
  24. ncbi A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrate
    Koonlawee Nademanee
    Pacific Rim Electrophysiology Research Institute, Inglewood, California 90301, USA
    J Am Coll Cardiol 43:2044-53. 2004
    We sought to test the hypothesis that complex fractionated electrograms (CFAEs) recorded during atrial fibrillation (AF) could be used as target sites for catheter ablation of AF.
  25. pmc Radiofrequency ablation for hepatocellular carcinoma: 10-year outcome and prognostic factors
    Shuichiro Shiina
    Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Am J Gastroenterol 107:569-77; quiz 578. 2012
    ..However, there has been no report on 10-year outcome of RFA. The objective of this study was to report a 10-year consecutive case series at a tertiary referral center...
  26. ncbi Radiofrequency ablation for hepatocellular carcinoma: updated review in 2010
    Masatoshi Kudo
    Department of Gastroenterology and Hepatology, Kinki University School of Medicine, Osaka, Japan m kudo med kindai ac jp
    Oncology 78:113-24. 2010
    ..Adjuvant therapy, such as interferon and molecular targeted therapies following curative therapy, is expected to further improve survival after RFA...
  27. pmc Thermal ablation for benign thyroid nodules: radiofrequency and laser
    Jung Hwan Baek
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138 736, Korea
    Korean J Radiol 12:525-40. 2011
    ..This article reviews the basic physics, techniques, applications, results, and complications of thyroid RF ablation, in comparison to laser ablation...
  28. ncbi Ganglionated plexi ablation for longstanding persistent atrial fibrillation
    Evgeny Pokushalov
    Arrhythmia Department, State Research Institute of Circulation Pathology, Novosibirsk, Russia
    Europace 12:342-6. 2010
    ..To study the potential efficacy of ganglionated plexi (GP) ablation in the setting of longstanding persistent atrial fibrillation (AF)...
  29. ncbi Comparison of antiarrhythmic drug therapy and radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation: a randomized controlled trial
    David J Wilber
    Cardiovascular Institute, Department of Medicine, Loyola University Medical Center, 2160 S First Ave, Bldg 110, Room 6232, Maywood, IL 60153, USA
    JAMA 303:333-40. 2010
    Antiarrhythmic drugs are commonly used for prevention of recurrent atrial fibrillation (AF) despite inconsistent efficacy and frequent adverse effects. Catheter ablation has been proposed as an alternative treatment for paroxysmal AF.
  30. ncbi Hepatic tumors treated with percutaneous radio-frequency ablation: CT and MR imaging follow-up
    Clarisse Dromain
    Department of Radiology, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Radiology 223:255-62. 2002
    ....
  31. ncbi Radiofrequency ablation for hepatocellular carcinoma abutting the diaphragm: the value of artificial ascites
    Hyunchul Rhim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam Gu, Seoul, Korea
    Abdom Imaging 34:371-80. 2009
    ..Complications related to the use of artificial ascites including hemoperitoneum are rare. Peritoneal adhesion and tumor location in the bare area are the limitations for the application of this technique...
  32. ncbi Early-stage hepatocellular carcinoma: radiofrequency ablation combined with chemoembolization versus hepatectomy
    Koichiro Yamakado
    Department of Radiology, Mie University School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Radiology 247:260-6. 2008
    ..To retrospectively evaluate the long-term results of radiofrequency (RF) ablation combined with chemoembolization (combination therapy) as compared with hepatectomy for the treatment of early-stage hepatocellular carcinoma (HCC)...
  33. ncbi Treatment of focal liver tumors with percutaneous radio-frequency ablation: complications encountered in a multicenter study
    Tito Livraghi
    Department of Radiology, Ospedale Civile, Vimercate, Italy
    Radiology 226:441-51. 2003
    ..To report complications encountered by members of a collaborative group who performed radio-frequency (RF) ablation in patients with focal liver cancer...
  34. ncbi Worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation
    Riccardo Cappato
    Arrhythmia and Electrophysiology Center, Policlinico San Donato, Via Morandi 30, 20097 San Donato Milanese, Milan, Italy
    Circulation 111:1100-5. 2005
    The purpose of this study was to conduct a worldwide survey investigating the methods, efficacy, and safety of catheter ablation (CA) of atrial fibrillation (AF).
  35. ncbi Small hepatocellular carcinoma in cirrhosis: randomized comparison of radio-frequency thermal ablation versus percutaneous ethanol injection
    Riccardo A Lencioni
    Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, I 56125 Pisa, Italy
    Radiology 228:235-40. 2003
    ..To compare the effectiveness of radio-frequency (RF) thermal ablation with that of percutaneous ethanol injection (PEI) for the treatment of small hepatocellular carcinoma (HCC) in patients with cirrhosis...
  36. ncbi Rapid pulmonary vein isolation combined with autonomic ganglia modification: a randomized study
    Demosthenes G Katritsis
    Department of Cardiology, Athens Euroclinic, Athens, Greece
    Heart Rhythm 8:672-8. 2011
    ..Evidence indicates that the combination of left atrial ganglionated plexi (GP) ablation and pulmonary vein (PV) isolation is beneficial for treatment of paroxysmal atrial fibrillation (AF)...
  37. ncbi Pulmonary vein isolation for the maintenance of sinus rhythm in patients with atrial fibrillation: a meta-analysis of randomized, controlled trials
    Jonathan P Piccini
    Division of Cardiology, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Circ Arrhythm Electrophysiol 2:626-33. 2009
    b>Catheter ablation is an established yet evolving nonpharmacologic intervention for the maintenance of sinus rhythm in patients with atrial fibrillation (AF)...
  38. ncbi Treatment of atrial fibrillation with antiarrhythmic drugs or radiofrequency ablation: two systematic literature reviews and meta-analyses
    Hugh Calkins
    Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Circ Arrhythm Electrophysiol 2:349-61. 2009
    Although radiofrequency catheter ablation (RFA) has evolved from an experimental procedure to an important treatment option for atrial fibrillation, the relative safety and efficacy of catheter ablation relative to that of antiarrhythmic ..
  39. ncbi HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for personnel, policy, procedures and follow-up. A report of the Heart Rhythm Society (HRS) Task Force on Catheter and Surgical Ablation of
    Hugh Calkins
    Johns Hopkins Hospital, Maryland, USA
    Europace 9:335-79. 2007
  40. ncbi Complications of radiofrequency coagulation of liver tumours
    S Mulier
    Department of General Surgery, University Hospital Mont Godinne, Catholic University of Louvain, Belgium
    Br J Surg 89:1206-22. 2002
    ..The purpose of this study was to assess critically the complication rates of RFC in centres with both large and limited initial experience, and to establish causes and possible means of prevention and treatment...
  41. ncbi Midterm outcomes in patients with intermediate-sized hepatocellular carcinoma: a randomized controlled trial for determining the efficacy of radiofrequency ablation combined with transcatheter arterial chemoembolization
    Manabu Morimoto
    Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan
    Cancer 116:5452-60. 2010
    ..To improve the efficacy of radiofrequency ablation (RFA) for the treatment of intermediate-sized hepatocellular carcinomas (HCCs), the authors compared RFA combined with transcatheter arterial chemoembolization (TACE) to RFA alone...
  42. pmc Randomised controlled trial comparing percutaneous radiofrequency thermal ablation, percutaneous ethanol injection, and percutaneous acetic acid injection to treat hepatocellular carcinoma of 3 cm or less
    S M Lin
    Liver Research Unit, Chang Gung Memorial Hospital, Chang Gung University, 199 Tung Hwa North Rd, Taipei, Taiwan
    Gut 54:1151-6. 2005
    ..The aim of this study was to compare the outcomes of radiofrequency thermal ablation (RFTA), percutaneous ethanol injection (PEI), and percutaneous acetic acid injection (PAI) in the treatment of hepatocellular carcinoma (HCC)...
  43. pmc Prophylactic catheter ablation for the prevention of defibrillator therapy
    Vivek Y Reddy
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, USA
    N Engl J Med 357:2657-65. 2007
    ..We designed this randomized trial to examine whether prophylactic radiofrequency catheter ablation of arrhythmogenic ventricular tissue would reduce the incidence of ICD therapy.
  44. ncbi Radiofrequency ablation versus hepatic resection for the treatment of hepatocellular carcinomas 2 cm or smaller: a retrospective comparative study
    Zhen wei Peng
    Department of Hepatobiliary Surgery, Cancer Centre of Sun Yat sen University, 651 Dongfeng Rd East, Guangzhou 510060, China
    Radiology 262:1022-33. 2012
    ..To compare retrospectively the effects of percutaneous radiofrequency (RF) ablation with those of hepatic resection in the treatment of hepatocellular carcinoma (HCC) measuring 2 cm or smaller...
  45. ncbi Dabigatran vs warfarin for radiofrequency catheter ablation of atrial fibrillation
    Jin Seok Kim
    Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48105 5853, USA
    Heart Rhythm 10:483-9. 2013
    It is not clear whether dabigatran is as safe and effective as uninterrupted anticoagulation with warfarin during radiofrequency catheter ablation (RFA) of atrial fibrillation (AF).
  46. ncbi Association between epicardial adipose tissue volumes on 3-dimensional reconstructed CT images and recurrence of atrial fibrillation after catheter ablation
    Koichi Nagashima
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 75:2559-65. 2011
    Whether epicardial adipose tissue (EAT) is independently associated with atrial fibrillation (AF) and outcome after catheter ablation (CA) for AF remains unclear.
  47. ncbi Systematic review of randomized trials for hepatocellular carcinoma treated with percutaneous ablation therapies
    Yun Ku Cho
    Department of Radiology, Seoul Veterans Hospital, Seoul, Korea
    Hepatology 49:453-9. 2009
    ..The definition of local tumor progression or major complication was not unified among the trials included in the meta-analysis...
  48. pmc Multiple-electrode radiofrequency ablations using Octopus® electrodes in an in vivo porcine liver model
    E S Lee
    Department of Radiology, Seoul NationalUniversity College of Medicine, Seoul, Republic of Korea
    Br J Radiol 85:e609-15. 2012
    ..The objective of this study was to determine the in vivo efficacy of radiofrequency ablation (RFA) in porcine liver using Octopus® electrodes for creating a large coagulation compared with RFA using clustered electrodes...
  49. ncbi Hybrid thoracoscopic surgical and transvenous catheter ablation of atrial fibrillation
    Laurent Pison
    Department of Cardiology, Maastricht University Medical Center and Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands
    J Am Coll Cardiol 60:54-61. 2012
    ..The purpose of this study was to evaluate the feasibility, safety, and clinical outcomes up to 1 year in patients undergoing combined simultaneous thoracoscopic surgical and transvenous catheter atrial fibrillation (AF) ablation...
  50. ncbi Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation
    Carlo Pappone
    Department of Cardiology, San Raffaele University Hospital, Via Olgettina 60, 20132, Milan, Italy
    Circulation 109:327-34. 2004
    ..This study assesses the incremental benefit of vagal denervation by radiofrequency in preventing recurrent AF in a large series of patients undergoing CPVA for paroxysmal AF...
  51. ncbi Safety and efficacy of pulmonary vein antral isolation in patients with obstructive sleep apnea: the impact of continuous positive airway pressure
    Dimpi Patel
    St David s Medical Center, Austin, TX, USA
    Circ Arrhythm Electrophysiol 3:445-51. 2010
    ..Obstructive sleep apnea (OSA) may be associated with pulmonary vein antrum isolation (PVAI) failure. The aim of the present study was to investigate if treatment with continuous positive airway pressure (CPAP) improved PVAI success rates...
  52. ncbi The minimal ablative margin of radiofrequency ablation of hepatocellular carcinoma (> 2 and < 5 cm) needed to prevent local tumor progression: 3D quantitative assessment using CT image fusion
    Young Sun Kim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul 135 710, Republic of Korea
    AJR Am J Roentgenol 195:758-65. 2010
    ....
  53. ncbi Predictive value of obstructive sleep apnoea assessed by the Berlin Questionnaire for outcomes after the catheter ablation of atrial fibrillation
    Karuna Chilukuri
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Europace 11:896-901. 2009
    Obstructive sleep apnoea (OSA) is a risk factor for atrial fibrillation (AF) recurrence after catheter ablation. The purpose of this study is to determine whether OSA assessed by the simple tool, the Berlin Questionnaire (BQ), is useful ..
  54. ncbi Radiofrequency ablation of atrial fibrillation: is the persistence of all intraprocedural targets necessary for long-term maintenance of sinus rhythm?
    Claudio Pratola
    St Anna University Hospital, Corso Giovecca 203, 44100 Ferrara, Italy
    Circulation 117:136-43. 2008
    Several approaches have been developed for radiofrequency catheter ablation of atrial fibrillation, but the correct intraprocedural end point is still under debate, and few data exist about the destiny of ablation lesions over time...
  55. ncbi Principles of and advances in percutaneous ablation
    Muneeb Ahmed
    Laboratory for Minimally Invasive Tumor Therapy, Section of Interventional Radiology, and Section of Abdominal Imaging, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 1 Deaconess Rd, Boston, MA 02215, USA
    Radiology 258:351-69. 2011
    ..Advances in technique will also be covered, including combination therapies, tissue property modulation, and the role of computer modeling for treatment optimization...
  56. pmc Image-guided tumor ablation: standardization of terminology and reporting criteria
    S Nahum Goldberg
    Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    Radiology 235:728-39. 2005
    ....
  57. ncbi Percutaneous radiofrequency ablation versus partial hepatectomy for multicentric small hepatocellular carcinomas: a nonrandomized comparative study
    Wei Xing Guo
    Eastern Hepatobiliary Surgery Hospital, The Second Military Medical University, No 225 Changhai Road, 200438, Shanghai, China
    World J Surg 34:2671-6. 2010
    ..With advances in RFA, it is not known whether the minimally invasive approach with percutaneous RFA could attain comparable survival outcomes but with a lower morbidity in patients with multicentric HCCs...
  58. ncbi Not only randomized controlled trials, but also case series should be considered in systematic reviews of rapidly developing technologies
    Duncan Chambers
    Centre for Reviews and Dissemination, University of York, UK
    J Clin Epidemiol 62:1253-1260.e4. 2009
    ..We evaluated the contribution of case series to a systematic review of radiofrequency catheter ablation (RFCA) for treatment of atrial fibrillation (AF).
  59. pmc Mechanochemical tumescentless endovenous ablation: final results of the initial clinical trial
    S Elias
    Columbia Vein Programmes, Columbia University, New York, NY, USA
    Phlebology 27:67-72. 2012
    ..The purpose of this study was to assess the safety and efficacy of the ClariVein(®) system that employs mechanochemical ablation of the great saphenous vein (GSV)...
  60. ncbi Efficacy and safety of periprocedural dabigatran in patients undergoing catheter ablation of atrial fibrillation
    Kenichi Kaseno
    Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3 12 Kameizumi, Maebashi 371 0004, Japan
    Circ J 76:2337-42. 2012
    ..Few studies, however, have evaluated the efficacy and safety of periprocedural dabigatran in AF ablation...
  61. ncbi Six year follow-up after catheter ablation of atrial fibrillation: a palliation more than a true cure
    Antonio Sorgente
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 109:1179-86. 2012
    ..In this study, 103 patients with symptomatic AF who underwent catheter ablation at a single academic medical center from 2002 to 2006 were evaluated, with a median follow-up time of 6 ..
  62. ncbi Utility of contrast-enhanced ultrasonography with Sonazoid in radiofrequency ablation for hepatocellular carcinoma
    Ryota Masuzaki
    Graduate School of Medicine, Department of Gastroenterology, The University of Tokyo, Tokyo, Japan
    J Gastroenterol Hepatol 26:759-64. 2011
    ..The utility of Sonazoid in radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC) was investigated in this study...
  63. ncbi Effect of epicardial fat pad ablation on acute atrial electrical remodeling and inducibility of atrial fibrillation
    Dong Chang
    Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China
    Circ J 74:885-94. 2010
    ..Atrial electrical remodeling (AER) is the underlying mechanism of atrial fibrillation (AF). The present study investigated the impact of epicardial fat pad (FP) ablation on acute AER (AAER) and inducibility of AF...
  64. ncbi Low efficacy of atrial fibrillation ablation in severe obstructive sleep apnoea patients
    Maria Matiello
    Arrhythmia Section, Cardiology Department, Thorax Institute, Hospital Clinic Universitari, Institut de Investigació Biomèdica August Pi i Sunyer, University of Barcelona, 08036 Barcelona, Catalonia, Spain
    Europace 12:1084-9. 2010
    ..Although the association of obstructive sleep apnoea (OSA) and AF is well established, data on AF ablation efficacy in OSA are scarce. The aim of this study was to clarify the effect of OSA on the outcome of AF ablation...
  65. ncbi High-sensitivity C-reactive protein as a predictor of atrial fibrillation recurrence after primary circumferential pulmonary vein isolation
    Jun Liu
    Center for Arrhythmia Diagnosis and Treatment, Fu Wai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
    Pacing Clin Electrophysiol 34:398-406. 2011
    ..However, it is unknown whether plasma hsCRP concentration before CPVI can be used as a predictor for AF recurrence...
  66. pmc Evaluation of the left atrial substrate in patients with lone atrial fibrillation using delayed-enhanced MRI: implications for disease progression and response to catheter ablation
    Christian Mahnkopf
    Comprehensive Arrhythmia and Research Management CARMA Center, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Heart Rhythm 7:1475-81. 2010
    ..Lone atrial fibrillation (AF) is thought to be a benign type or an early stage of the disease...
  67. pmc The long- and short-term impact of elevated body mass index on the risk of new atrial fibrillation the WHS (women's health study)
    Usha B Tedrow
    Center for Arrhythmia Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Coll Cardiol 55:2319-27. 2010
    ..The purpose of this study was to characterize the relationship between changes in body mass index (BMI) and incident atrial fibrillation (AF) in a large cohort of women...
  68. ncbi Prevention of biliary complication in radiofrequency ablation for hepatocellular carcinoma-Cooling effect by endoscopic nasobiliary drainage tube
    Tsuneyoshi Ogawa
    Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Eur J Radiol 73:385-90. 2010
    ..The purpose of this study is to clarify the feasibility and safety of bile duct cooling using an endoscopic nasobiliary drainage (ENBD) tube in RFA for HCC close to major bile ducts...
  69. ncbi The current role of radiofrequency ablation in the management of hepatocellular carcinoma: a systematic review
    Wan Yee Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Ann Surg 249:20-5. 2009
    ..To review the current status of radiofrequency ablation (RFA) in the management of hepatocellular carcinoma (HCC)...
  70. ncbi Catheter ablation versus antiarrhythmic drugs for atrial fibrillation: the A4 study
    Pierre Jais
    Hopital Cardiologique du Haut Leveque, Avenue de Magellan, 33604 Bordeaux Pessac, France
    Circulation 118:2498-505. 2008
    The mainstay of treatment for atrial fibrillation (AF) remains pharmacological; however, catheter ablation has increasingly been used over the last decade. The relative merits of each strategy have not been extensively studied.
  71. ncbi Outcomes and complications of catheter ablation for atrial fibrillation in females
    Dimpi Patel
    St David s Medical Center, Texas Cardiac Arrhythmia Institute, Austin, TX, USA
    Heart Rhythm 7:167-72. 2010
    Most atrial fibrillation (AF) ablation studies have consisted predominantly of males; accordingly, there is a paucity of information on the safety and efficacy of catheter ablation in a large cohort of female AF patients.
  72. ncbi Medium-sized (3.1-5.0 cm) hepatocellular carcinoma: transarterial chemoembolization plus radiofrequency ablation versus radiofrequency ablation alone
    Jin Hyoung Kim
    Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
    Ann Surg Oncol 18:1624-9. 2011
    ..1-5.0 cm) hepatocellular carcinoma (HCC)...
  73. ncbi Long-term results of atrial fibrillation ablation: the importance of all initial ablation failures undergoing a repeat ablation
    Roger A Winkle
    Cardiovascular Medicine and Cardiac Arrhythmias, E Palo Alto, CA 94303, USA
    Am Heart J 162:193-200. 2011
    ..Many patients fail initial ablation and undergo repeat ablations. Little is known about repeat ablation procedure times, complications, and outcomes...
  74. ncbi How effective is cryoablation for atrial fibrillation during concomitant cardiac surgery?
    Christian Fielder Camm
    New College, University of Oxford, Holywell Street, Oxford OX1 3BN, UK
    Interact Cardiovasc Thorac Surg 13:410-4. 2011
    ..We conclude that cryoablation during concomitant surgery is a safe and acceptable intervention for the treatment of AF with an SR conversion rate of between 60% and 82% at 12-months postsurgery...
  75. ncbi Robotic navigation in catheter ablation for paroxysmal atrial fibrillation: midterm efficacy and predictors of postablation arrhythmia recurrences
    Peter Hlivák
    Department of Cardiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    J Cardiovasc Electrophysiol 22:534-40. 2011
    Remote navigation systems represent a novel strategy for catheter ablation of atrial fibrillation (AF)...
  76. ncbi Patients treated with catheter ablation for atrial fibrillation have long-term rates of death, stroke, and dementia similar to patients without atrial fibrillation
    T Jared Bunch
    Intermountain Heart Rhythm Specialists Department of Cardiology, Intermountain Medical Center, Murray, Utah 84107, USA
    J Cardiovasc Electrophysiol 22:839-45. 2011
    ..AF ablation eliminates AF in most patients. We evaluated the long-term impact of AF ablation on mortality, heart failure (HF), stroke, and dementia in a large system-wide patient population...
  77. pmc Radiofrequency ablation vs hepatic resection for solitary colorectal liver metastasis: a meta-analysis
    Yun Zi Wu
    Department of Hepato Biliary Pancreato Vascular Surgery, The First Affiliated Hospital of Xiamen University, Xiamen 361003, Fujian Province, China
    World J Gastroenterol 17:4143-8. 2011
    ..To evaluate the comparative therapeutic efficacy of radiofrequency ablation (RFA) and hepatic resection (HR) for solitary colorectal liver metastases (CLM)...
  78. ncbi Incidence of silent cerebral thromboembolic lesions after atrial fibrillation ablation may change according to technology used: comparison of irrigated radiofrequency, multipolar nonirrigated catheter and cryoballoon
    Fiorenzo Gaita
    Cardiology Division, Department of Internal Medicine, San Giovanni Battista Hospital, University of Turin, Italy
    J Cardiovasc Electrophysiol 22:961-8. 2011
    ..The study purpose is to compare the incidence of new silent cerebral ischemic events in patients with paroxysmal atrial fibrillation (PAF) undergoing PVI with different ablation technologies...
  79. ncbi Neutrophil-to-lymphocyte ratio associated with mortality in early hepatocellular carcinoma patients after radiofrequency ablation
    Tsung Ming Chen
    Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
    J Gastroenterol Hepatol 27:553-61. 2012
    ..We studied whether peripheral blood neutrophil-to-lymphocyte ratio (NLR), a marker of systemic inflammatory response, would be a useful predictor for outcome in patients with early HCC undergoing radiofrequency ablation (RFA)...
  80. ncbi Five-year survival in 309 patients with colorectal liver metastases treated with radiofrequency ablation
    A R Gillams
    University College Hospital and University College London Medical School, London, UK
    Eur Radiol 19:1206-13. 2009
    ..There were 23/617(3.7%) local complications requiring intervention. Five-year survival of 24-33% post ablation in selected patients is superior to any published chemotherapy data and approaches the results of liver resection...
  81. ncbi Long-term outcome after successful catheter ablation of atrial fibrillation
    Wendy S Tzou
    Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    Circ Arrhythm Electrophysiol 3:237-42. 2010
    ..We determined 5-year outcomes of PVI among patients with freedom from AF off antiarrhythmic drugs (AAD) for 1 year after PVI...
  82. ncbi Feasibility and safety of remote-controlled magnetic navigation for ablation of atrial fibrillation
    William T Katsiyiannis
    Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA
    Am J Cardiol 102:1674-6. 2008
    ..In conclusion, radiofrequency ablation of AF performed with RMN is safe and feasible. Compared with conventional hand-navigated ablation, RMN ablation results in similar clinical outcomes with decreased fluoroscopy and procedure times...
  83. ncbi Catheter ablation of long-standing persistent atrial fibrillation: a lesson from circumferential pulmonary vein isolation
    Roland Richard Tilz
    II Medizinische Abteilung, Asklepios Klinik St Georg, Hamburg, Germany
    J Cardiovasc Electrophysiol 21:1085-93. 2010
    ..However, in patients with long-standing persistent AF, the ideal ablation strategy still remains a matter of debate...
  84. ncbi Radiofrequency ablation for incidentally identified primary intrahepatic cholangiocarcinoma
    Witold Zgodzinski
    Second Department of General Surgery, Skubiszewski Medicaal University of Lublin, Poland
    World J Gastroenterol 11:5239-40. 2005
    ..The patient remained free of disease 24 mo after the procedure, and is still followed up. This is the first report of RFA application in the treatment of primary intrahepatic cholangiocarcinoma...
  85. ncbi Prevention of ventricular fibrillation episodes in Brugada syndrome by catheter ablation over the anterior right ventricular outflow tract epicardium
    Koonlawee Nademanee
    Pacific Rim Electrophysiology Research Institute, 1700 Cesar E Chavez Avenue, Los Angeles, CA 90033, USA
    Circulation 123:1270-9. 2011
    ..who have frequent recurrent VF episodes, the substrate site is the RVOT, either over the epicardium or endocardium; abnormal electrograms would be identified at this location, which would serve as the target site for catheter ablation.
  86. ncbi Radiofrequency thermal ablation vs. percutaneous ethanol injection for small hepatocellular carcinoma in cirrhosis: meta-analysis of randomized controlled trials
    Ambrogio Orlando
    Department of Medicine, Pneumology and Nutrition Clinic, V Cervello Hospital, University of Palermo, Piazza Mameli 1, Palermo, Italy
    Am J Gastroenterol 104:514-24. 2009
    ..The aim of the study was to review the available evidence comparing RF to PEI for small HCC...
  87. ncbi Treatment of hepatocellular carcinoma with radiofrequency ablation: radiologic-histologic correlation during follow-up periods
    Manabu Morimoto
    Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan
    Hepatology 35:1467-75. 2002
    ..These pathologic findings can be correlated with those of contrast-enhanced CT...
  88. ncbi Radiofrequency tumor ablation: principles and techniques
    S N Goldberg
    Laboratory of Minimally Invasive Therapy, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 300 Brookline Avenue, Boston, MA 02215, USA
    Eur J Ultrasound 13:129-47. 2001
    ..Lastly, the principles governing safe usage of the system, such as proper grounding pad placement, will be adressed...
  89. ncbi Repeated radiofrequency ablation for management of patients with cirrhosis with small hepatocellular carcinomas: a long-term cohort study
    Sandro Rossi
    VI Department of Internal Medicine, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
    Hepatology 53:136-47. 2011
    ..5%) cases. No procedure-related deaths occurred in 1,921 RFA sessions. Estimated 3- and 5-year overall and disease-free (after repeated RFAs) survival rates were 67.0% and 40.1% and 68.0 and 38.0%, respectively...
  90. ncbi Minimally-invasive thermal ablation of early-stage breast cancer: a systemic review
    Z Zhao
    Department of Medical Information, Chongqing Medical University, Chongqing 400016, China
    Eur J Surg Oncol 36:1149-55. 2010
    ..Minimally-invasive thermal ablation techniques provide an effective approach for local destruction of solid tumor. A novel application is the use for treatment of early-stage breast carcinoma...
  91. ncbi Planning sonography to assess the feasibility of percutaneous radiofrequency ablation of hepatocellular carcinomas
    Hyunchul Rhim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, IlWon Dong, Kangnam Ku, Seoul 135 710, Korea
    AJR Am J Roentgenol 190:1324-30. 2008
    ..The objective of our study was to evaluate the feasibility rate and the reasons for infeasibility of percutaneous radiofrequency ablation of hepatocellular carcinomas (HCCs) at planning sonography...
  92. ncbi The role of ganglionated plexi in apnea-related atrial fibrillation
    Muhammad Ghias
    Heart Rhythm Institute, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    J Am Coll Cardiol 54:2075-83. 2009
    ..This study was conducted to simulate sleep apnea-induced atrial fibrillation (AF) in an experimental model and to determine whether neural ablation will prevent AF...
  93. ncbi Low-dose, long-term, intermittent interferon-alpha-2b therapy after radical treatment by radiofrequency ablation delays clinical recurrence in patients with hepatitis C virus-related hepatocellular carcinoma
    Yasuhiro Sakaguchi
    Department of Gastroenterology and Hepatology, Kinki University School of Medicine, Osaka Sayama, Osaka, Japan
    Intervirology 48:64-70. 2005
    ..To assess whether or not interferon (IFN) therapy prevents recurrence, and eventually improves the prognosis of patients with hepatocellular carcinoma (HCC) after completion of radical radiofrequency ablation (RFA) therapy...
  94. ncbi Multiple-electrode radiofrequency ablation of in vivo porcine liver: comparative studies of consecutive monopolar, switching monopolar versus multipolar modes
    Jeong Min Lee
    Department of Radiology, Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Korea
    Invest Radiol 42:676-83. 2007
    ..To evaluate the in vivo efficiency of 2 multiple-electrode radiofrequency (RF) systems to create confluent areas of coagulation in porcine liver, compared with consecutive overlapping ablation...
  95. ncbi Ultrasonography-guided percutaneous radiofrequency ablation of hepatocellular carcinomas: a feasibility scoring system for planning sonography
    Hyunchul Rhim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Eur J Radiol 75:253-8. 2010
    ....
  96. pmc Neural mechanisms of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia in ambulatory canines
    Alex Y Tan
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Circulation 118:916-25. 2008
    ..The relationship between autonomic activation and the mechanisms of paroxysmal atrial fibrillation remains unclear...
  97. ncbi Meta-analysis of obstructive sleep apnea as predictor of atrial fibrillation recurrence after catheter ablation
    Chee Yuan Ng
    Cedars Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    Am J Cardiol 108:47-51. 2011
    ..However, studies on the role of OSA on AF recurrence after catheter ablation have yielded conflicting results...
  98. pmc Computed tomography-guided transpulmonary radiofrequency ablation for hepatocellular carcinoma located in hepatic dome
    Mitsuo Toyoda
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3 39 15 Showa Machi, Maebashi, Gunma 371 8511, Japan
    World J Gastroenterol 12:608-11. 2006
    ..To determine the feasibility of performing computed tomography (CT)-guided transpulmonary radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) located in the hepatic dome...
  99. ncbi A randomized controlled trial of radiofrequency ablation with ethanol injection for small hepatocellular carcinoma
    Shuichiro Shiina
    Department of Gastroenterology, University of Tokyo, Japan
    Gastroenterology 129:122-30. 2005
    ..Percutaneous radiofrequency ablation is a recently introduced treatment for hepatocellular carcinoma, whereas ethanol injection is now a standard therapy. We compared their long-term outcomes...
  100. ncbi Circumferential pulmonary-vein ablation for chronic atrial fibrillation
    Hakan Oral
    Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, USA
    N Engl J Med 354:934-41. 2006
    ..We conducted a randomized, controlled trial of circumferential pulmonary-vein ablation for the treatment of chronic atrial fibrillation...
  101. ncbi A randomized double-blind study of epicardial left atrial cryoablation for permanent atrial fibrillation in patients undergoing mitral valve surgery: the SWEDish Multicentre Atrial Fibrillation study (SWEDMAF)
    Carina Blomstrom-Lundqvist
    Department of Cardiology, Uppsala University Hospital, SE 75185 Uppsala, Sweden
    Eur Heart J 28:2902-8. 2007
    ..The efficacy of epicardial left atrial (LA) cryoablation in eliminating atrial fibrillation (AF) in patients undergoing mitral valve surgery (MVS) is unknown. We hypothesized that MVS combined with LA cryoablation is superior to MVS alone...

Research Grants62

  1. Substrate Mapping & Ablation of Ventricular Tachycardia
    Vivek Reddy; Fiscal Year: 2006
    ..Radiofrequency (RF) catheter ablation is an effective less-invasive alternative, but is largely limited to hemodynamically-tolerated VT-which ..
  2. Functional Assessment of the Locus for Atrial Fibrillation on Chromosome 4q25
    PATRICK THOMAS ELLINOR; Fiscal Year: 2010
    ..Ectopic electrical foci within the pulmonary veins initiates fibrillatory activity and is the target of catheter ablation procedures used to treat AF...
  3. Targeted cell therapy for the treatment of ventricular tachycardia
    KENNETH LAURITA; Fiscal Year: 2010
    ..Radiofrequency (RF) catheter ablation can cure arrhythmias associated with MI;however, many patients are not suitable and the recurrence rate is ..
  4. Comparative effectiveness of catheter ablation vs medical therapy for atrial fibr
    James Freeman; Fiscal Year: 2013
    ..6 million by 2050. Catheter ablation for atrial fibrillation (AF), using radiofrequency energy or cryotherapy to electrically isolate the ..
  5. Rational Design of New Drugs to Treat Ventricular Arrhythmias
    Jonathan J Abramson; Fiscal Year: 2012
    ..or suppression of episodes of ventricular tachycardia include implantable cardioverter-defibrillators (ICD), catheter ablation, and anti-arrhythmic drugs...
  6. Applications of Magnetic Resonance for Management of Ventricular Tachycardia
    Saman Nazarian; Fiscal Year: 2013
    ..Implantable defibrillators cause painful shocks and decrease quality of life, and catheter ablation is associated with failures deriving from the inability to visualize the VT substrate with fluoroscopy...
  7. Patterns of Health Care Use, Treatment &Outcomes in Atrial Fibrillation: PATH-AF
    SUSAN HECKBERT; Fiscal Year: 2012
    ..treat AF patients, including the use of home monitoring devices to measure INR and the use of radiofrequency catheter ablation. Again, in subgroup analyses we will examine differential use by age, sex, race, and geography...
  8. Cardiac Magnetic Resonance IMaging During Arrhythmia
    Aravindan Kolandaivelu; Fiscal Year: 2013
    ..While many tachy-arrhythmias are curable by catheter ablation, some common conditions, in particular atrial fibrillation and ventricular tachycardia (VT), are sub-..
  9. Improved Targeting and Assessment of Electrophysiology Intervention
    Henry R Halperin; Fiscal Year: 2013
    ..These arrhythmias can be cured with catheter ablation, but the arrhythmias often recur...
  10. Contemporary Treatment and Outcomes for Atrial Fibrillation in Clinical Practice
    DANIEL EDWIN SINGER; Fiscal Year: 2010
    ..g., catheter ablation and surgical ablation)...
  11. Vein of Marshall Ethanol Infusion for Persistent Atrial Fibrillation
    Miguel Valderrabano; Fiscal Year: 2013
    ..this project is to evaluate the therapeutic value of vein of Marshall (VOM) ethanol infusion when added to catheter ablation of atrial fibrillation (AF)...
  12. ANCILLARY STUDY OF SUBSTRATE AND INTERVENTION MECHANISMS FOR MALIGNANT ARRHYTHMIA
    Saman Nazarian; Fiscal Year: 2013
    ..details of the VT substrate and its effects upon patient response to antiarrhythmic drug therapy and catheter ablation, an alternative mode of therapy that aims to destroy the VT substrate...
  13. Real-time MRI-guided RF Ablation of Cardiac TachyArrhythmias
    Orhan Unal; Fiscal Year: 2010
    ..However, catheter ablation guided by X-ray fluoroscopy (XRF) with adjunctive electroanatomic/ mechanical mapping (EMM) is challenging ..
  14. Three Dimensional Electrocardiographic Imaging
    Bin He; Fiscal Year: 2010
    ..critical foundation for establishing the proposed 3-DEIT as a novel tomographic imaging modality to guide catheter ablation of arrhythmias, and to develop and to assess the effects of new therapeutic approaches targeted to specific ..
  15. High Frequency Ultrasound Arrays for Cardiac Imaging
    David J Sahn; Fiscal Year: 2012
    ..such as the rapid and irregular rhythms referred to as atrial fibrillation, often require treatment by trans-catheter ablation procedures...
  16. Low-Dose Tomosynthetic Interventional System For Quantitative Cardiac Imaging
    Michael A Speidel; Fiscal Year: 2013
    ..of conventional fluoroscopy also fails to provide the 3D device and anatomic information needed for modern catheter ablation procedures...
  17. Image-based models that predict arrhythmia morphology in post-infarction hearts
    HERMENEGILD JAVIER AREVALO; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): While catheter ablation to terminate ventricular tachycardia (VT) due to myocardial infarction (Ml) has been shown to be a promising therapy, the technique's 30% failure rate in treating ..
  18. Catheter Ablation versus Antiarrythmic Drug Therapy for Atrial Fibrilllation Tria
    Douglas L Packer; Fiscal Year: 2013
    The investigator-initiated, Catheter Ablation Versus Anti-arrhythmic Drug Therapy for Atrial Fibrillation (CABANA) Trial will test the hypothesis that the treatment strategy of percutaneous left atrial catheter ablation for the purpose ..
  19. CABANA-AF Trial
    Kerry L Lee; Fiscal Year: 2013
    The investigator-initiated, Catheter Ablation Versus Anti-arrhythmic Drug Therapy for Atrial Fibrillation (CABANA) Trial will test the hypothesis that the treatment strategy of percutaneous left atrial catheter ablation for the purpose ..
  20. Cabana Image Analysis Lab
    Richard A Robb; Fiscal Year: 2013
    The investigator-initiated, Catheter Ablation Versus Anti-arrhythmic Drug Therapy for Atrial Fibrillation (CABANA) Trial will test the hypothesis that the treatment strategy of percutaneous left atrial catheter ablation for the purpose ..
  21. WAVEFORM AND FREQUENCY ANALYSES TO DIAGNOSE ATRIAL TACHYCARDIAS AFTER ATRIAL FIBR
    Angelo Biviano; Fiscal Year: 2013
    ..intracardiac electrograms to classify and localize arrhythmias that develop in patients after percutaneous catheter ablation for atrial fibrillation...
  22. Rapid High-Resolution Electroanatomical Cardiac Mapping System for the Treatment
    DORON HARLEV; Fiscal Year: 2009
    ..Minimally invasive procedures, such as catheter ablation, have established themselves as the preferred approach to eliminating cardiac arrhythmias and restoring ..
  23. Cardothoracic Surgery Network
    JOHN DANIEL PUSKAS; Fiscal Year: 2013
    ..have significantly greater freedom from AF 12 months after minimally invasive surgical ablation than after catheter ablation, measured by an autocapture continuous event monitor...
  24. Late gadolinium enhancement cardiovascular MR for the Detection of Pre-Existent L
    Dana C Peters; Fiscal Year: 2011
    ..this LGE CMR method, we will study control subjects and patients prior to undergoing treatment either by catheter ablation, minimally invasive surgery, or drug therapy...
  25. Method for guiding ablative therapy of cardiac arrythmias
    Antonis A Armoundas; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Ventricular catheter ablation has been established as the most desirable from cost and patient safety point of view approach in treating cardiac arrhythmias, yet its success rate has not broad ..
  26. Novel 3D Catheter Tracking System for Intracardiac Navigation
    DORON HARLEV; Fiscal Year: 2009
    ..Minimally invasive procedures, such as catheter ablation, are quickly emerging as the preferred approach to eliminate cardiac arrhythmias and restore normal heart ..
  27. Laser Cather for Ablation of Ventricular Tachycardia
    Ashok Gowda; Fiscal Year: 2002
    ..b>Catheter ablation has been shown to be an effective means for curing many arrhythmias, but current approaches are not able to ..
  28. MRI Compatible Electrode Catheter System
    STEVEN WEDAN; Fiscal Year: 2009
    ..arrhythmias can be cured by selective destruction of critical electrical pathways with radiofrequency (RF) catheter ablation. Attempts at applying ablation to atrial fibrillation and ventricular tachycardia have been made...
  29. LASER CATHETER FOR ABLATION OF VENTRICULAR TACHYCARDIA
    Ashok Gowda; Fiscal Year: 1999
    ..b>Catheter ablation has been shown to be an effective means for curing many arrhythmias, but current approaches are not able to ..
  30. MODEL BASED INTERPRETATION OF INTRACARDIAC ELECTROGRAMS
    David Tong; Fiscal Year: 2000
    b>Catheter ablation is a medical procedure that involves the destruction of small volumes of heart tissue with radiofrequency energy. To be successful, catheter ablation requires precise localization of the tissue to be destroyed...
  31. New Technologies in Electrophysiology Intervention
    Henry Halperin; Fiscal Year: 2005
    ..Another major limitation is the lack of ability to visualize ablated areas of myocardium during catheter ablation procedures. Dr...
  32. MRI Compatible Electrode Catheter System
    YAKOV GELFAND; Fiscal Year: 2003
    ..arrhythmias can be cured by selective destruction of critical electrical pathways with radiofrequency (RF) catheter ablation. Attempts at applying ablation to atrial fibrillation and ventricular tachycardia have been made...
  33. Virtual cardiac electrophysiologic testing for sudden death risk stratification
    Jason Ng; Fiscal Year: 2010
    ..of electrical dyssynchrony in candidates for bi- ventricular pacing therapy, pre-procedure planning for catheter ablation of patients with documented ventricular tachycardias, and as an educational software tool for training ..
  34. Atrionodal Bundles:Histologic and Physiologic Validation
    DARLENE RACKER; Fiscal Year: 2005
    Radiofrequency (RF) catheter ablation of either the "slow" or "fast" AV nodal pathways can cure AV node reentrant tachycardia (AVNRT) and also modify ventricular response to atrial flutter and fibrillation...
  35. PROSPECTIVE ASSESSMENT AFTER PEDIATRIC CARDIAC ABLATION
    George Van Hare; Fiscal Year: 2002
    DESCRIPTION: (Adapted from Investigator's Abstract) Radiofrequency catheter ablation is a catheterization laboratory technique for the cure of cardiac arrhythmias, which has become common in pediatric cardiology practice...
  36. Phased Array Ultrasound System for Cardiac Ablation
    Kullervo Hynynen; Fiscal Year: 2006
    ..Despite these major advances, catheter ablation has major limitations effecting both efficacy and safety...
  37. ATRIAL FIBRILLATION: ANATOMY VERSUS CELL PHYSIOLOGY
    HAROLD HASTINGS; Fiscal Year: 2003
    ..fibrillation to become sustained, the anticipated clinical relevance to treatments such as radiofrequency catheter ablation is significant, in that it may be possible to develop more effective ablation patterns by taking into ..
  38. X-RAY BACKSCATTER IMAGING OF VENTRICULAR ACTIVATION
    JOSEPH MC INERNEY; Fiscal Year: 1990
    ..Death usually results from ventricular tachycardia degenerating into fibrillation. Surgical and trans-catheter ablation therapies have emerged from the treatment of such arrhythmias...
  39. NEW TECHNIQUE FOR QUANTIFYING ATRIAL FIBRILLATION
    DAVID KYNOR; Fiscal Year: 1999
    ..in selecting optimal treatment regimes for patients and for guiding specific interventions including catheter ablation, cardioversion, and administration of antiarrhythmic medications...
  40. MICROWAVE DEVICE FOR MYOCARDIAL ABLATION
    KENNETH CARR; Fiscal Year: 1991
    ..This configuration would allow intraoperative ablation or catheter ablation for treatment of cardiac arrhythmias, particularly ventricular tachyarrhythmias...
  41. CLINICAL TRIAL MANAGAEMENT OF FIBRILLATION
    H Greene; Fiscal Year: 2000
    ..In the second strategy, a different group of drugs and/or catheter ablation will be used for the purpose of heart rate control only...
  42. BODY SURFACE LOCALIZATION OF QRS LATE POTENTIALS
    Roger Freedman; Fiscal Year: 1991
    ..Substantiation of this hypothesis would allow for noninvasive determination of the extent and location of arrhythmogenic myocardium in patients with ventricular arrhythmias, which may help direct surgical and catheter ablation.
  43. Electric Micro-Steerable catheter using smart electroactive polymers
    Shihai Zhang; Fiscal Year: 2009
    ..This will enable the wide accessibility and acceptance of the life-saving curative catheter ablation to millions of Americans threaded by cardiac arrhythmias.
  44. A NOVEL ENDOCARDIAL MAPPING SYSTEM
    DAVID KYNOR; Fiscal Year: 2000
    b>Catheter ablation has become the treatment of choice for many types of arrhythmias largely because it is curative, safe, and relatively inexpensive...
  45. Computer-guided designer ablation of atrial fibrillation
    ELIZABETH CHERRY; Fiscal Year: 2004
    b>Catheter ablation techniques to treat chronic reentrant atrial fibrillation (AF) have been largely unsuccessful...
  46. The Pathophysiology of T-wave Alternans
    Sanjiv Narayan; Fiscal Year: 2005
    ..This structured approach will ensure the successful completion of this project and, in this way, the development of the applicant into an independent clinician-investigator. ..
  47. Visualizing the Substrate for Sudden Cardiac Death
    Vivek Reddy; Fiscal Year: 2006
    ..First, catheter ablation procedures to eliminate VT could be precisely targeted by pre-procedural MR imaging and 3D reconstruction to ..
  48. Gene Targets of NKX 2.5 in the Conduction System
    Melvin Scheinman; Fiscal Year: 2004
    ..MinK and HCN-1) in the pathogenesis of arrhythmias in the ventricular restricted knockout mouse model. This will be done by using in-situ hybridization and immunohistochemistry to follow the pattern of expression of these ion channels. ..
  49. Epidemiologic Case-control Study of Barrett's Esophagus
    Nicholas Shaheen; Fiscal Year: 2005
    ..Finally, by comparing subjects with Barrett's to controls with reflux, and controlling for severs of reflux, the impact of a Barrett's diagnosis on quality of life and psychological stress may be seen. ..
  50. The Perception of Cancer Risk in Patients with Barrett's Esophagus
    Nicholas Shaheen; Fiscal Year: 2007
    ..The resultant study application will assess health-related quality of life, health-related anxiety and healthcare utilization as outcomes. [unreadable] [unreadable]..
  51. Percutaneous Removal & Margin Ablation for Breast Cancer
    VICKI KLIMBERG; Fiscal Year: 2004
    ..abstract_text> ..
  52. Tau Nitration in Alzheimer's Pathogenesis
    Matthew Reynolds; Fiscal Year: 2007
    ..In this proposal, we will characterize the specific sites of T nitration in vitro and in situ, and determine the effects of nitration on T folding and function. ..
  53. Cost Effectiveness of Catheter Ablation for Atrial Fibrillation (AF)
    Matthew Reynolds; Fiscal Year: 2008
    ..Electrical isolation of the pulmonary veins from the left atrium with radiofrequency catheter ablation has recently emerged as an important new therapy for AF...
  54. Interneuronal mechanisms for the control of walking
    Jianguo Cheng; Fiscal Year: 2009
    ....
  55. Advancing an Evidence-Based Approach to Barrett's Esophagus: A Health Outcomes Re
    Chin Hur; Fiscal Year: 2007
    ..We plan to published the proceedings of the meeting and anticipate future project collaborations, grant applications as well as new investigators will arise as a result of this conference. [unreadable] [unreadable] [unreadable]..
  56. Image-guided Fetal Cardiac Intervention
    John Triedman; Fiscal Year: 2005
    ..abstract_text> ..
  57. Barrett's Esophagus Ablation with Celocoxib Trial
    Charles Lightdale; Fiscal Year: 2002
    ..Patients will be accrued during the first study year, and will be followed until the last patient enrolled completes one year of treatment. ..
  58. Towards a Non-Invasive Therapy for Atrial Fibrillation
    Benjamin Scherlag; Fiscal Year: 2004
    ..This new therapeutic approach could be utilized as a non-invasive application or incorporated into an implantable device for treatment of patients with PAF. ..