cytapheresis

Summary

Summary: Separation of one or more kinds of cells from whole blood with the return of other blood cell constituents to the patient or donor. This is accomplished with an instrument that uses centrifugation to separate the cells into different layers based on the differences in cell density (displacement) or drag coefficients in a current (elutriation). The procedure is commonly used in adoptive transfer to isolate NK cells, lymphocytes, or monocytes.

Top Publications

  1. doi Long-term prognosis of patients with ulcerative colitis treated with cytapheresis therapy
    Tetsuro Takayama
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
    J Crohns Colitis 7:e49-54. 2013
  2. ncbi Predicting the clinical response to cytapheresis in steroid-refractory or -dependent ulcerative colitis using contrast-enhanced ultrasonography
    Toshiki Yamaguchi
    Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Scand J Gastroenterol 44:831-7. 2009
  3. ncbi A pilot study on the efficacy of ketorolac plus tramadol infusion combined with erythrocytapheresis in the management of acute severe vaso-occlusive crises and sickle cell pain
    Lucia De Franceschi
    Haematologica 89:1389-91. 2004
  4. ncbi Efficacy of granulocytapheresis and leukocytapheresis for the treatment of microscopic polyangiitis
    Midori Hasegawa
    Department of Nephrology, Fujita Health University School of Medicine, Aichi, Japan
    Ther Apher Dial 8:212-6. 2004
  5. ncbi A new treatment for HCV-ulcerative colitis comorbidity intolerant to INF-alpha
    Koji Sawada
    Am J Gastroenterol 98:228-9. 2003
  6. doi Quality of leucoreduced red blood cell concentrates: 5 years of follow-up in France
    A Chabanel
    Etablissement Français du Sang, Paris, France
    Vox Sang 94:41-7. 2008
  7. ncbi Granulocyte and monocyte adsorptive apheresis in a case with severe ulcerative colitis unresponsive to conventional medication
    Yasuo Suzuki
    The Second Department of Internal Medicine, Chiba University School of Medicine, Chiba, Japan
    J Clin Apher 18:40-2. 2003
  8. ncbi Use of cellular and plasma apheresis in the critically ill patient: Part II: Clinical indications and applications
    Michael L Linenberger
    Apheresis and Cellular Therapy, Seattle Cancer Care Alliance, Seattle, WA 98109, USA
    J Intensive Care Med 20:88-103. 2005
  9. ncbi Administration of erythopoietin and granulocyte colony-stimulating factor in donor/recipient pairs to collect peripheral blood progenitor cells (PBPC) and red blood cell units for use in the recipient after allogeneic PBPC transplantation
    B Sautois
    Department of Medicine, Division of Haematology, , , Belgium
    Haematologica 86:1209-18. 2001
  10. ncbi Why do some apheresis donors donate blood just once?
    J Ringwald
    Department of Transfusion Medicine and Haemostaseology, University Hospital of Erlangen, D 91054 Erlangen, Germany
    Vox Sang 93:354-62. 2007

Research Grants

  1. EOSINOPHIL AND BASOPHIL GRANULE PROTEINS
    Gerald Gleich; Fiscal Year: 2001

Detail Information

Publications134 found, 100 shown here

  1. doi Long-term prognosis of patients with ulcerative colitis treated with cytapheresis therapy
    Tetsuro Takayama
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
    J Crohns Colitis 7:e49-54. 2013
    Although accumulating studies in Japan show that cytapheresis (CAP) therapy is safe and effective for the induction of remission of moderate or severe ulcerative colitis (UC), the long-term prognosis of UC patients treated with CAP is ..
  2. ncbi Predicting the clinical response to cytapheresis in steroid-refractory or -dependent ulcerative colitis using contrast-enhanced ultrasonography
    Toshiki Yamaguchi
    Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Scand J Gastroenterol 44:831-7. 2009
    To evaluate the usefulness of transabdominal ultrasound (US), including contrast-enhanced ultrasonography (CEUS), in predicting the response to cytapheresis therapy in patients with steroid-refractory or -dependent ulcerative colitis (UC).
  3. ncbi A pilot study on the efficacy of ketorolac plus tramadol infusion combined with erythrocytapheresis in the management of acute severe vaso-occlusive crises and sickle cell pain
    Lucia De Franceschi
    Haematologica 89:1389-91. 2004
    ..Here we report a pilot study which combined balanced analgesia with tramadol plus ketorolac and erythrocytapheresis. Key words: sickle cell disease, therapeutic erythrocytapheresis, HbS, visual analog scale, vaso-occlusive crisis...
  4. ncbi Efficacy of granulocytapheresis and leukocytapheresis for the treatment of microscopic polyangiitis
    Midori Hasegawa
    Department of Nephrology, Fujita Health University School of Medicine, Aichi, Japan
    Ther Apher Dial 8:212-6. 2004
    ..All four lung hemorrhage episodes were ameliorated. We concluded that combined therapy of GCAP or LCAP and corticosteroids is effective for the treatment of RPGN and lung hemorrhage due to microscopic polyangiitis...
  5. ncbi A new treatment for HCV-ulcerative colitis comorbidity intolerant to INF-alpha
    Koji Sawada
    Am J Gastroenterol 98:228-9. 2003
  6. doi Quality of leucoreduced red blood cell concentrates: 5 years of follow-up in France
    A Chabanel
    Etablissement Français du Sang, Paris, France
    Vox Sang 94:41-7. 2008
    ..Since 1998, prestorage leucoreduction of all cellular blood components has been made mandatory in France. The French blood service needed to follow the data on the quality of the blood components prepared by blood centres...
  7. ncbi Granulocyte and monocyte adsorptive apheresis in a case with severe ulcerative colitis unresponsive to conventional medication
    Yasuo Suzuki
    The Second Department of Internal Medicine, Chiba University School of Medicine, Chiba, Japan
    J Clin Apher 18:40-2. 2003
  8. ncbi Use of cellular and plasma apheresis in the critically ill patient: Part II: Clinical indications and applications
    Michael L Linenberger
    Apheresis and Cellular Therapy, Seattle Cancer Care Alliance, Seattle, WA 98109, USA
    J Intensive Care Med 20:88-103. 2005
    ..Ongoing studies are investigating the potential utility of conventional plasma exchange, ex vivo plasma manipulation, and newer technologies for these and other disorders in severely ill patients...
  9. ncbi Administration of erythopoietin and granulocyte colony-stimulating factor in donor/recipient pairs to collect peripheral blood progenitor cells (PBPC) and red blood cell units for use in the recipient after allogeneic PBPC transplantation
    B Sautois
    Department of Medicine, Division of Haematology, , , Belgium
    Haematologica 86:1209-18. 2001
    ....
  10. ncbi Why do some apheresis donors donate blood just once?
    J Ringwald
    Department of Transfusion Medicine and Haemostaseology, University Hospital of Erlangen, D 91054 Erlangen, Germany
    Vox Sang 93:354-62. 2007
    ..We interviewed returning (RBD) and non-returning apheresis BDs (NRBD) of our university hospital-based BDS...
  11. ncbi [Indications of urgent plasma exchange and cytapheresis therapies--a review based on literature data and personal experience]
    Mihály Belák
    Országos Gyógyintézeti Központ, Belgyógyászati és Geriatriai Klinika
    Orv Hetil 147:1843-8. 2006
    ..Similarly, urgent thrombocytapheresis should be administered above platelet numbers 1000 G/l, when there is concomitant thrombophilia or clinical symptoms of thrombostasis are present...
  12. ncbi Treatment of pyoderma gangrenosum associated with Crohn's disease
    Toshihide Ohmori
    Am J Gastroenterol 98:2101-2. 2003
  13. ncbi Development of a rare cell fractionation device: application for cancer detection
    Hisham Mohamed
    Wadsworth Center, New York State Department of Health, Albany, NY 12201, USA
    IEEE Trans Nanobioscience 3:251-6. 2004
    ..Devices designed to capture rare cells in peripheral circulation for downstream analysis will provide an important tool for diagnosis and treatment...
  14. ncbi Guidelines for policies on alternatives to allogeneic blood transfusion. 1. Predeposit autologous blood donation and transfusion
    F E Boulton
    National Blood Service, Southampton, UK
    Transfus Med 17:354-65. 2007
  15. ncbi Multicomponent collection as of 2005
    M Valbonesi
    Department of Immunohematology, San Martino University Hospital, Largo Rosanna Benzi 10, 16132 Genova, Italy
    Transfus Apher Sci 32:287-97. 2005
    ..In terms of donor acceptance it is our experience that, since 1989 no donor has refused MCC, consisting at least in the concurrent collection of plasma along with platelets, but also RBC and or a second unit of platelets...
  16. ncbi Use of cellular and plasma apheresis in the critically ill patient: part 1: technical and physiological considerations
    Michael L Linenberger
    Seattle Cancer Care Alliance, Seattle, WA 98109, USA
    J Intensive Care Med 20:18-27. 2005
    ..Part 2 of this series will deal with the clinical indications and applications for specific disorders that are most likely to affect patients in the intensive care unit...
  17. ncbi Treatment with cytapheresis for antineutrophil cytoplasmic antibody-associated renal vasculitis and its effect on anti-inflammatory factors
    Midori Hasegawa
    Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    Ther Apher Dial 9:297-302. 2005
    To evaluate the efficacy of cytapheresis for the treatment of rapidly progressive glomerulonephritis (RPGN) caused by myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA)-associated vasculitis, the renal prognosis and the ..
  18. ncbi Cytapheresis for the treatment of myeloperoxidase antineutrophil cytoplasmic autoantibody-associated vasculitis: a pilot study of 21 patients
    Midori Hasegawa
    Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    Ther Apher Dial 10:412-8. 2006
    ..myeloperoxidase-antineutrophil cytoplasmic autoantibody (MPO-ANCA)-associated vasculitis were treated using cytapheresis. Of these, 17 were treated for glomerulonephritis and four were treated for pulmonary hemorrhage...
  19. pmc Sensitive PCR method for the detection and real-time quantification of human cells in xenotransplantation systems
    M Becker
    , , 13092 Berlin, Germany
    Br J Cancer 87:1328-35. 2002
    ..4) Engraftment studies with blood stem cells originating from cytapheresis samples of tumour patients or from cord blood were undertaken in NOD/SCID mice in order to define conditions of ..
  20. pmc Exploring the feasibility of selective depletion of T lymphocyte subsets by whole blood immunoadsorption cytapheresis
    M Belak
    Section of Hematology and Oncology, Department of Medicine, Boston University Medical Center, Boston, MA, USA
    Clin Exp Immunol 150:477-86. 2007
    ..It is possible that such apheresis techniques could achieve targeted forms of immunosuppression not possible with drugs or radiation...
  21. pmc Ten-year follow-up of unrelated volunteer granulocyte donors who have received multiple cycles of granulocyte-colony-stimulating factor and dexamethasone
    Karen Quillen
    Department of Transfusion Medicine, Warren G Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    Transfusion 49:513-8. 2009
    ..The short-term side effects of G-CSF are well studied, but the potential long-term effects of repeated G-CSF stimulation in unrelated volunteer granulocyte donors have not been reported...
  22. ncbi Cytapheresis in the treatment of cell-affected blood disorders and abnormalities
    Bela Balint
    Department of Experimental Hematology, Institute for Medical Research, Belgrade, Serbia and Montenegro
    Transfus Apher Sci 35:25-31. 2006
    ..The best clinical effect and long-term benefits were obtained using RBCX and antimalarial drugs in malaria patients who have had high-level parasitized-RBCs with multiorgan dysfunction...
  23. ncbi Evaluation of a new apheresis system for the collection of leukoreduced single-donor platelets
    Jürgen Zingsem
    Department of Transfusion Medicine and Haemostaseology, University Hospital Erlangen, Erlangen, Germany
    Transfusion 47:987-94. 2007
    ..cell concentrates (WBCs) and leukoreduced single-donor platelet concentrates (SDPs) and performing therapeutic cytapheresis and plasmapheresis that might replace the Fresenius systems AS104 and AS.TEC 204...
  24. doi [A contribution to a study of apoptosis of hematopoietic stem cells CD34+ by flow cytometry before and after cryopreservation]
    M Ben Nasr
    Laboratoire d immunologie cellulaire et de cytométrie, centre national de transfusion sanguine de Tunis, 11, rue Djebel Lakdhar Bab Sa, BP 294 El Manar II 2092, Tunis, Tunisie
    Transfus Clin Biol 15:91-7. 2008
    ..But, we have noted a pronounced induction of apoptosis in peripheral mobilized blood compared to cytapheresis (after cryopreservation: 29.79% of apoptotic HSC CD34+ in peripheral mobilized blood but only 11...
  25. doi Immunoadsorption in dermatology
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, 23560, Lubeck, Germany
    Arch Dermatol Res 302:241-53. 2010
    ..effective and specific tool advantageous to plasmapheresis to remove immunoglobulin and immune complexes and in cytapheresis, immune cells from the circulation. IA was successfully used in various autoantibody-mediated diseases, e.g...
  26. ncbi Donor-derived hematopoietic stem cells in organ transplantation: technical aspects and hurdles yet to be cleared
    Patrick Herve
    Establissement Français du Sang Borgogne Franche Comté, Besancon, France
    Transplantation 75:55S-57S. 2003
    ..The best yield of HSC is obtained from vertebral bodies. HSC harvesting by cytapheresis after cell mobilization with a cytokine such as granulocyte colony-stimulating factor should be preferred with ..
  27. pmc Cytapheresis in patients with severe ulcerative colitis after failure of intravenous corticosteroid: a long-term retrospective cohort study
    Ken Fukunaga
    Division of Lower Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan
    Gut Liver 3:41-7. 2009
    b>Cytapheresis (CAP) is a novel strategy for ulcerative colitis (UC). However, there is insufficient data on the long-term outcome of UC patients who achieve remission by CAP...
  28. pmc DNAM-1 and PVR regulate monocyte migration through endothelial junctions
    Nicolas Reymond
    Institut National de la Santé et de la Recherche Médicale UMR599, Institut de Cancérologie de Marseille, IFR 137, 27 Bd Lei Roure, 13009 Marseille, France
    J Exp Med 199:1331-41. 2004
    ..Altogether, our results demonstrate that DNAM-1 regulates monocyte extravasation via its interaction with PVR expressed at endothelial junctions on normal cells...
  29. ncbi Lymphocytapheresis in the treatment of psoriasis vulgaris
    Giancarlo Maria Liumbruno
    Apheresis Unit of Blood Bank and Transfusion Service, Hospital of Livorno, Livorno, Italy
    J Clin Apher 21:158-64. 2006
    ..Since cytapheresis has been widely applied to autoimmune disorders, emphasizing the recently reported results of granulocyte and ..
  30. doi CD34+ cells obtained from "good mobilizers" are more activated and exhibit lower ex vivo expansion efficiency than their counterparts from "poor mobilizers"
    Zoran Ivanovic
    Aquitaine Limousin Branch of French Blood Institute and the University Victor Segalen Bordeaux 2, Bordeaux, France
    Transfusion 50:120-7. 2010
    ..We hypothesized that, apart from their mobilization from marrow to the blood, the response to G-CSF of CD34+ cells also includes activation of proliferation, metabolic activity, and proliferative capacity...
  31. ncbi Cytapheresis with a filter for selective removal of CD4+ T cells in experimental autoimmune encephalomyelitis
    Shunya Nakane
    Department of Neurology, Kawatana National Hospital, Nagasaki, Japan
    Mult Scler 9:579-84. 2003
    ..These results suggest that depletion of CD4+ T cells from the systemic circulation by extracorporeal treatment is a potentially useful strategy for treatment of acute phase and relapsing MS...
  32. ncbi Release of potential immunomodulatory factors during platelet storage
    Fabrice Cognasse
    EFS Auvergne Loire, Saint Etienne, France
    Transfusion 46:1184-9. 2006
    ..Recent studies have demonstrated that PLTs promote immunity and inflammation mainly by means of the CD40/CD40L pathway. Our objective was to describe the accumulation of cytokines in PLT concentrates during storage...
  33. ncbi Adverse events and problems in therapeutic hemapheresis. A report from the Swedish registry
    R Norda
    Department of Transfusion Medicine and Immunohemotherapy, Orebro Medical Center Hospital, Sweden
    Transfus Apher Sci 25:33-41. 2001
    ..Since 1996 adverse events (AE) in therapeutic apheresis (TA) have been more extensively registered in Sweden. This report analyzes the extent and relation of AEs to procedures and diagnoses...
  34. doi Persistence of lymphocyte function perturbations after granulocyte-colony-stimulating factor mobilization and cytapheresis in normal peripheral blood stem cell donors
    Caroline Marmier-Savet
    INSERM, Universite de Franche Comte, IFR133, and Etablissement Français du Sang, Bourgogne Franche Comté, UMR 645, Besancon, France
    Transfusion 50:2676-85. 2010
    ..In this respect, duration of G-CSF-induced perturbations has been less studied than short-term effects and needs to be evaluated...
  35. ncbi Pharmaco-economic study of intensive chemotherapy with peripheral blood progenitor cell support for advanced breast cancer
    F Pinguet
    Pharmacy Oncopharmacology Department, Val d Aurelle Anticancer Center, Parc Euromedecine, 34298 Montpellier Cedex 05, France
    Oncol Rep 8:1013-7. 2001
    ..We collected the data from the induction chemotherapy cycle (followed by cytapheresis) to the end of the hospitalisation for autograft...
  36. ncbi [The indication of steroid pulse therapy and apheresis therapy for multiple sclerosis]
    Satoru Ohji
    Department of Neurology, Saitama Medical Center, Saitama Medical University
    Nihon Rinsho 66:1127-32. 2008
    ..Apheresis therapy includes plasmapheresis and cytapheresis, and plasmapheresis includes plasma exchange (PE) and immunoadsorption plasmapheresis (IAPP)...
  37. ncbi Ex vivo cytokine expansion of peripheral blood Ph-negative cells in chronic myeloid leukaemia
    F X Mahon
    Laboratoire de Greffe de Moelle, UMR CNRS 5540, FR60, Universite Victor Segalen Bordeaux 2, France
    Leuk Lymphoma 32:151-7. 1998
    ..Therefore ex vivo expansion of putatively normal hematopoietic progenitor cells from cytapheresis is feasible in CML.
  38. ncbi Correction of hyperviscosity by apheresis
    Mirjana Zarkovic
    Hematology Oncology Division, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Semin Thromb Hemost 29:535-42. 2003
    ..purification technique designed for the removal of either plasma (plasmapheresis) or cellular blood components (cytapheresis)...
  39. pmc Transfusion immunomodulation--the case for leukoreduced and (perhaps) washed transfusions
    Katie L Lannan
    Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Blood Cells Mol Dis 50:61-8. 2013
    ..The present review will focus on two approaches, leukoreduction and saline washing, as means to reduce adverse transfusion outcomes...
  40. doi Safety of hematopoietic stem cell donation in glucose 6 phosphate dehydrogenase-deficient donors
    F Pilo
    Unità Operativa Ematologia e Centro Trapianti Midollo Osseo, Ospedale Oncologico di Riferimento Regionale Armando Businco, Cagliari, Italy
    Bone Marrow Transplant 48:36-9. 2013
    ..No difference was found in transplant outcome. From this retrospective analysis, we conclude that a G6PD-deficient but otherwise healthy volunteer can be selected as a HSC donor...
  41. doi Analysis of 120 pediatric patients with nonmalignant disorders transplanted using unrelated plasma-depleted or -reduced cord blood
    Lawrence Petz
    StemCyte International Cord Blood Center, Covina, California 91722, USA
    Transfusion 52:1311-20. 2012
    ..However, there are relatively limited data regarding outcomes of CB transplants using units processed by PDR...
  42. pmc Automated processing of whole blood units: operational value and in vitro quality of final blood components
    Marisa Jurado
    Community Transfusion Centre, Madrid, Spain
    Blood Transfus 10:63-71. 2012
    ..Interim platelet unit are pooled to produce a transfusable platelet unit. In this study the Atreus 3C system was evaluated and compared to the routine method with regards to product quality and operational value...
  43. ncbi In vitro and in vivo evaluation of Adacolumn cytapheresis in healthy subjects
    Wolfgang Ramlow
    Dialysis Group North, Rostock, Germany
    J Clin Apher 20:72-80. 2005
    Adacolumn is a medical device for adsorptive cytapheresis. It has been developed for selective adsorption of granulocytes and monocytes from peripheral blood of patients with immune disorders, such as autoimmune diseases and chronic ..
  44. doi Utility of impedance cardiography for the detection of hemodynamic changes in stable patients with sickle cell disease
    Bibhuti B Das
    Department of Pediatrics, Division of Pediatric Cardiology, University of Texas Southwestern Medical Center, Dallas, TX 75235, USA
    J Pediatr Hematol Oncol 34:336-9. 2012
    ..The study sought to assess the potential utility of impedance cardiography (ICG) to detect hemodynamic changes after erythrocytapheresis in stable children with sickle cell disease (SCD)...
  45. doi Questionnaire based assessment of patients' acceptability of leukocytapheresis for the treatment of inflammatory bowel disease
    Kazuko Nagase
    Department of Internal Medicine, Division of Lower, Hyogo College of Medicine, Nishinomiya, Japan
    Ther Apher Dial 17:490-7. 2013
    The aim of the present study was to assess patients' acceptance of therapeutic leukocytapheresis known as cytapheresis (CAP) for the treatment of an active flare of inflammatory bowel disease (IBD)...
  46. ncbi Leucocytapheresis with Adacolumn enhances HCV-specific proliferative responses in patients infected with hepatitis C virus genotype 1
    Helmut M Diepolder
    Institute for Immunology, University of Munich, Germany
    J Med Virol 77:209-15. 2005
    ..This study examined the effect of cytapheresis on the subsequent response to interferon/ribavirin treatment in patients infected with HCV...
  47. doi Short-term femoral catheter insertion: a promising alternative to consistently allow long-term erythrocytapheresis therapy in children with sickle cell anemia
    Marie Billard
    Hospices Civils de Lyon, Lyon, France
    J Pediatr 162:423-6. 2013
    ..We have successfully used short-term femoral catheter insertion, during a 6.5-year period for a total of 443 procedures, to perform long-term erythrocytapheresis in 18 consecutive children with sickle cell disease...
  48. ncbi Pilot clinical study of Adacolumn cytapheresis in patients with systemic lupus erythematosus
    Helmut Soerensen
    Hospital Waldfriede, Berlin, Germany
    Rheumatol Int 26:409-15. 2006
    The aim of this study is to investigate the clinical effects of cytapheresis using the Adacolumn system (selective removal of circulating monocytes and granulocytes by means of an extracorporeal type column) in patients with active ..
  49. ncbi [Extracorporeal photochemotherapy for treatment of clonal T cell proliferations]
    Joel Plumas
    Unité mixte de therapie cellulaire et tissulaire, EFS Rhone Alpes, BP 35, 38701, La Tronche, France
    Bull Cancer 90:763-70. 2003
    ..Mononuclear cells are harvested by cytapheresis and reinfused to the patient after irradiation...
  50. ncbi [Therapeutic apheresis in multiple sclerosis]
    Kyoichi Nomura
    Department of Neurology, Saitama Medical School
    Nihon Rinsho 61:1388-95. 2003
    Therapeutic apheresis is divided in cytapheresis and plasmapheresis. And plasmapheresis(PP) is divided into three treatments, plasma exchange(PE), double filtration plasmapheresis(DFPP) and immunoadsorption plasmapheresis(IAPP)...
  51. doi Beyond dialysis: current and emerging blood purification techniques
    Bernd Stegmayr
    Department of Public Health and Medicine, Umeå University and Division of Nephrology, Department of Internal Medicine, University Hospital, Umea, Sweden
    Semin Dial 25:207-13. 2012
    ..This comprises therapeutic apheresis (plasma exchange and cytapheresis), plasma adsorption, hemoperfusion, and the bio-artificial devices.
  52. ncbi Stem cell harvesting protocol research in autologous transplantation setting: large volume vs. conventional cytapheresis
    Bela Balint
    Military Medical Academy, Institute of Transfusiology, Belgrade, Serbia
    Vojnosanit Pregl 65:545-51. 2008
    ..The basic goal of the study was to evaluate the influence of apheresis protocol (collection timing, processed blood volume and cell yield) upon the clinical outcome of transplantation...
  53. doi Differentiation of monocyte-derived dendritic cells under the influence of platelets
    X D Nguyen
    Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, Red Cross Blood Donation Service of Baden Wurttemberg Hessen, Germany
    Cytotherapy 10:720-9. 2008
    ..Platelets (Plt) are invariably found as a contaminant in the final monocytapheresis product. The aim of this study was to investigate DC differentiation under the influence of Plt with regard to their function and phenotype...
  54. doi Granulocytapheresis in the treatment of patients with active ulcerative colitis
    Giampaolo Bresci
    U O Gastroenterologia, Azienda Ospedaliera Universitaria Pisana, Via A Della Spina, Pisa 1156125, Italy
    Expert Rev Gastroenterol Hepatol 2:639-43. 2008
    ..This article will review the clinical applications and issues concerning the use of granulocytapheresis in ulcerative colitis...
  55. doi How I treat hemochromatosis
    Paul C Adams
    University Hospital, University of Western Ontario, London, ON, Canada
    Blood 116:317-25. 2010
    ....
  56. ncbi Cell salvage and leucodepletion
    M H Cross
    Department of Anaesthesia, The General Infirmary at Leeds, UK
    Perfusion 16:61-6. 2001
    ..This may be due to bradykinin production following platelet exposure to negatively charged leucocyte filters...
  57. doi Peripheral blood stem cell recovery following early termination of apheresis due to hypotension in a 4.8-kg infant
    Jessie Alex
    DeGowin Blood Center, Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
    J Clin Apher 24:120-1. 2009
    ..If the procedure must be terminated early, sufficient PBSC may be recoverable from the blood in the apheresis instrument...
  58. ncbi Plasma level of granulocyte-colony stimulating factor during granulocyte and monocyte adsorptive apheresis in patients with ulcerative colitis
    Hiroaki Takeda
    Division of Endoscopy, Yamagata University Hospital, Yamagata, Japan
    Hepatogastroenterology 56:348-51. 2009
    b>Cytapheresis with extra-corporeal circulation for ulcerative colitis is effective but its mechanisms are still unclear...
  59. doi Comparison of the efficacy of granulocyte and monocyte/macrophage adsorptive apheresis and leukocytapheresis in active ulcerative colitis patients: a prospective randomized study
    Yasuhisa Sakata
    Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Saga, Japan
    Eur J Gastroenterol Hepatol 20:629-33. 2008
    ..Recently, cytapheresis has emerged as a new treatment for patients with UC...
  60. ncbi [Episcleritis and erythema nodosum in a patient with ulcerative colitis]
    Satoshi Maekawa
    Third Department of Internal Medicine, Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine
    Nihon Shokakibyo Gakkai Zasshi 105:686-91. 2008
    ..Although concurrent onset of episcleritis and erythema nodosum associated with UC is also extremely rare, clinical course in this case suggests a possible association among ulcerative colitis, episcleritis and erythema nodosum...
  61. doi Cytapheresis in inflammatory bowel diseases: current evidence and perspectives
    Silvio Danese
    Division of Gastroenterology, Istituto Clinico Humanitas, IRCCS in Gastroenterology, University of Milan, Rozzano Milan, Italy
    Digestion 77:96-107. 2008
    ....
  62. pmc Regulatory T cells in patients with inflammatory bowel diseases treated with adacolumn granulocytapheresis
    Emilio Cuadrado
    Immunology Unit, Hospital Donostia, P o doctor Begiristain s n, Donostia 20014, San Sebastian, Spain
    World J Gastroenterol 14:1521-7. 2008
    ....
  63. ncbi Current topics on cytapheresis technologies
    K Yamaji
    Department of Internal Medicine and Rheumatology, Juntendo University, Tokyo, Japan
    Ther Apher 5:287-92. 2001
    b>Cytapheresis has been investigated recently for the treatment of autoimmune related diseases, such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), multiple sclerosis, and so on...
  64. ncbi Assessment of corrected QT interval in sickle-cell disease patients who undergo erythroapheresis
    C Boga
    Department of Hematology, Baskent University Faculty of Medicine, Ankara, Turkey
    Transfus Med 17:466-72. 2007
    ..Fifty percent QTc values returned to baseline after the procedure. The independent variables were not significantly associated with QTc interval. Exchange procedures can induce QTc prolongation in patients with SCD...
  65. ncbi Effects of cytapheresis on tumor necrosis factor receptor and on expression of CD63 in myeloperoxidase--antineutrophil cytoplasmic autoantibody-associated vasculitis
    Midori Hasegawa
    Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    Ther Apher Dial 11:337-40. 2007
    To evaluate the therapeutic potential of cytapheresis in myeloperoxidase-antineutrophil cytoplasmic autoantibody (MPO-ANCA)-associated vasculitis, plasma levels of soluble tumor necrosis factor receptors (sTNFR1, sTNFR2) and the ..
  66. doi Mobilized allogeneic peripheral stem/progenitor cell apheresis with Spectra Optia v.5·0, a novel, automatic interface-controlled apheresis system: results from the first feasibility trial
    S Bräuninger
    German Red Cross Blood Service Baden Wuerttemberg Hesse, Institute Frankfurt, and Institute for Transfusion Medicine and Immunohematology of Goethe University Medical Center, Frankfurt, Germany
    Vox Sang 101:237-46. 2011
    ....
  67. ncbi Quantitative expression of adhesion molecules on granulocyte colony-stimulating factor-mobilized peripheral blood, bone marrow, and cord blood CD34+ cells
    C Gigant
    , LEMTA UMR CNRS 7563, , , France
    J Hematother Stem Cell Res 10:807-14. 2001
    ..Finally, the quantitative expression of the main receptors on CD34(+) cells explained cellular functions during the different steps of hematopoietic stem cells transplantation...
  68. ncbi Bi-phasic CD34+ cell mobilization of a syngeneic donor during prolonged G-CSF delivery
    S M Arnold
    Division of Hematology and Oncology, Markey Cancer Center, University of Kentucky, Chandler Medical Center, Kentucky 40536, USA
    Cytotherapy 1:119-22. 1999
    G-CSF administration over 10 days and neutrophil cytapheresis have been reported in the literature, but the kinetics of CD34+ cells in this situation is unclear.
  69. ncbi Filtration of malignant cells: tumour cell depletion in an ex vivo model using a leukocyte adhesion filter
    N R Fruhauf
    Abteilung für Allgemein und Transplantationschirurgie, Westdeutsches Tumorzentrum Universitätsklinikum Essen, Germany
    Perfusion 16:51-5. 2001
    ..These experiments and further investigation are supposed to help to reduce the risk of dissemination of tumour cells in patients undergoing oncological surgery...
  70. ncbi Erythrocytapheresis for Plasmodium falciparum infection complicated by cerebral malaria and hyperparasitemia
    Y Zhang
    Department of Pathology, Blood Bank Division, University of Texas Medical Branch, Galveston, Texas, USA
    J Clin Apher 16:15-8. 2001
    ..In combination with effective anti-malarial chemotherapy, apheresis RCE is a safe and rapid approach to treat complicated malaria due to P. falciparum...
  71. ncbi Erythrocytapheresis limits iron accumulation in chronically transfused sickle cell patients
    L M Hilliard
    Department of Pediatrics, University of Alabama at Birmingham, USA
    Am J Hematol 59:28-35. 1998
    ..Erythrocytapheresis is a safe method of controlling Hb S levels and limiting or preventing iron load in chronically transfused sickle cell patients...
  72. ncbi Biocompatibility of a new cell separator studied by flow cytometry: analyses of platelet antigens during apheresis and storage
    K Gutensohn
    Department of Transfusion Medicine Transplantation Immunology, University Hospital Eppendorf, University of Hamburg, Germany
    Transfusion 39:742-7. 1999
    Alterations of platelet antigens are known to occur during cytapheresis and storage. These changes have been shown to be dependent on the biomaterials, techniques, and devices used...
  73. ncbi Long-term immune recovery after CD34+ immunoselected and unselected peripheral blood progenitor cell transplantation: a case-control study
    L Laurenti
    Divisione di Ematologia, Istituto Semeiotica Medica, Universita Cattolica Sacro Cuore, Largo A Gemelli 8, 00168 Rome, Italy
    Haematologica 84:1100-3. 1999
    ..We compared the long term immunologic recovery in two groups of patients submitted to CD34+ PBPCT or unselected autologous peripheral blood progenitor cell transplantation (uPBPCT)...
  74. ncbi Autologous stem cell transplantation for acute myeloid leukemia in first remission
    C A Linker
    University of California, San Francisco, USA
    Biol Blood Marrow Transplant 6:50-7. 2000
    ..Preliminary efficacy analysis is very encouraging, with outcomes that appear superior to those of conventional chemotherapy...
  75. ncbi National survey of hemapheresis practice in Turkey (1998)
    O Ilhan
    Department of Hematology, Ankara University Medical School, Hemapheresis Unit, Sihhiye 06100, Ankara, Turkey
    Transfus Sci 22:195-201. 2000
    ..Therapeutic cytapheresis procedures like leukapheresis, plateletapheresis and erythrocyte apheresis were performed especially for ..
  76. ncbi Do automated red cell exchanges relieve priapism in patients with sickle cell anemia?
    L J McCarthy
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine and Indiana University Hospital, Indianapolis 46202 5283, USA
    Ther Apher 4:256-8. 2000
    ..One adult experienced resolution 8 h postexchange. However, he had a history of "stuttering" priapism. All required decompression procedures. Automated RBC exchanges were not effective in achieving detumescence or reducing pain...
  77. doi Conventional apheresis therapies: a review
    David M Ward
    Division of Nephrology, University of California San Diego, San Diego, California, USA
    J Clin Apher 26:230-8. 2011
    This article reviews advances in the scientific basis and medical practice of plasmapheresis and cytapheresis therapies...
  78. doi Use of hemovigilance data to evaluate the effectiveness of diversion and bacterial detection
    Pierre Robillard
    Institut National de Sante Publique du Quebec, Montreal, Canada
    Transfusion 51:1405-11. 2011
    ..We evaluated the effectiveness of these measures in Québec using hemovigilance data from January 2000 to December 2008...
  79. doi Treatment of acute carbon-monoxide poisoning with therapeutic erythrocytapheresis: clinical effects and results in 17 victims
    Alper Celikdemir
    Department of Emergency, Faculty of Medicine, University of Cukurova, 01330 Adana, Turkey
    Transfus Apher Sci 43:327-9. 2010
    ..None of the patients died. Two victims (11.7%) experienced ischemic encephalopathy. Therapeutic red cell-exchange therapy can be an effective treatment in reducing mortality and morbidity in carbon-monoxide poisoning...
  80. ncbi Therapeutic apheresis
    J P Isbister
    Royal North Shore Hospital of Sydney, St. Leonards, New South Wales, Australia
    Indian J Pediatr 68:61-7. 2001
    ..This requires successful cooperation between medical, nursing and scientific personnel...
  81. doi The impact of a regular erythrocytapheresis programme on the acute and chronic complications of sickle cell disease in adults
    Anna Kalff
    Department of Laboratory Haematology, Royal Melbourne Hospital, Vic, Australia
    Br J Haematol 149:768-74. 2010
    ..Regular ECP was demonstrated to be an effective, well-tolerated therapy for both acute and chronic complications of SCD in adults...
  82. ncbi In vitro production of dendritic cells from human blood monocytes for therapeutic use
    L Garderet
    INSERM U76, , Paris et Fontenay Aux Roses, France
    J Hematother Stem Cell Res 10:553-67. 2001
    ..The results obtained demonstrate that the experimental conditions we set up are easily applicable in clinical trials and lead to large numbers of well-defined DC. Clinical trials using DC already published will be discussed...
  83. doi Are cell salvage and autologous blood transfusion safe in endonasal surgery?
    Shane Anderson
    The University of Queensland, The Princess Alexandra Hospital, Department of Otolaryngology Head and Neck Surgery, Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Otolaryngol Head Neck Surg 142:S3-6. 2010
    ..In this literature review, we present the evidence for perioperative cell saver blood transfusion in potentially contaminated fields and the need for further investigation of its use in endonasal surgery...
  84. ncbi Mathematical modeling and computer simulation of erythrocytapheresis for SCD
    T P Nifong
    Department of Pathology, Pennsylvania State College of Medicine, Hershey, Pennsylvania, USA
    Transfusion 41:256-63. 2001
    ..CONCLUSION: Computer modeling of erythrocytapheresis can be used to optimize chronic treatment regimens for SCD patients and potentially to minimize the risks of overtransfusion...
  85. doi Applications of platelet-rich fibrin matrix in facial plastic surgery
    Anthony P Sclafani
    Director of Facial Plastic Surgery, The New York Eye and Ear Infirmary, New York, New York 10003, USA
    Facial Plast Surg 25:270-6. 2009
    ..PRFM provides autologous, natural, but concentrated platelet growth factor release and stimulation of surrounding tissue. This article describes its use for cosmetic facial applications...
  86. ncbi Mobilization of peripheral blood progenitor cells after DHAP regimen with or without rituximab: a large multicenter comparative study in patients with malignant lymphoma
    Regis Peffault De Latour
    Department of Clinical Hematology, Institut Curie, Paris, France
    Leuk Lymphoma 48:897-904. 2007
    ..The first cytapheresis was performed at day 10 in the R-DHAP group versus day 11 in the DHAP group...
  87. ncbi Granulocyte and monocyte adsorptive apheresis for patients with chronic hepatitis C virus infection: a report on six cases with high plasma viremia
    Koji Sawada
    Department of Gastroenterology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
    Ther Apher Dial 7:547-53. 2003
    ..The most effective frequency of GMA needs to be determined in future clinical studies...
  88. ncbi Cytapheresis for the treatment of myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculitis: report of five cases
    Midori Hasegawa
    Department of Nephrology, Fujita Health University School of Medicine, Aichi, Japan
    Ther Apher 6:443-9. 2002
    ..RPGN) and one patient with pulmonary hemorrhage due to MPO-ANCA-associated vasculitis were treated by cytapheresis. The prednisolone (PSL) dose was 0.28 +/- 0.15 mg/kg/day (mean +/- SD) (range 0.18-0.50 g/kg/day)...
  89. ncbi Erythrocytapheresis plus erythropoietin: an alternative therapy for selected patients with hemochromatosis and severe organ damage
    Raffaella Mariani
    Haematologica 90:717-8. 2005
    ..Results indicate that this regimen could be a valid therapeutic alternative in complicated HH patients. Its cost, however, limits its use to patients whose clinical conditions prevent a proper phlebotomy regimen...
  90. ncbi Quality of packed red blood cells and platelet concentrates collected by multicomponent collection using the MCS plus device
    G C Leitner
    Department of Blood Group Serology and Transfusion Medicine, University of Vienna, Vienna, Austria
    J Clin Apher 18:21-5. 2003
    ..These results indicate less storage lesion in MCC-derived PRBCs compared to manually collected units and no compromise in the quality of MCC PCs obtained in the same apheresis procedure...
  91. ncbi Apheresis for MPO-ANCA-associated RPGN-indications and efficacy: lessons learned from Japan nationwide survey of RPGN
    Kunihiro Yamagata
    Department of Nephrology, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan
    J Clin Apher 20:244-51. 2005
    ..In this situation, cytapheresis is the treatment of choice...
  92. ncbi Cost of autologous peripheral blood stem cell transplantation: the Norwegian experience from a multicenter cost study
    V Mishra
    Health Professional Support Department, Rikshospitalet University Hospital, Oslo, Norway
    Bone Marrow Transplant 35:1149-53. 2005
    ..Average total costs were considerably higher than actual DRG-based reimbursement from the government, indicating that the treatment of these patients was heavily subsidized by the basic hospital grants...
  93. ncbi [Therapeutic hemapheresis]
    Eli Taraldsrud
    Immunologisk og transfusjonsmedisinsk avdeling
    Tidsskr Nor Laegeforen 123:2439-42. 2003
    ..This is the first survey of therapeutic hemapheresis in Norway. The purpose was to collect data from all Norwegian dialysis and blood units performing hemapheresis treatment and stem cell collection for comparison with Swedish data...
  94. ncbi Surgery sans blood
    Dan Emerson
    Minn Med 87:30-1. 2004
  95. ncbi Cytapheresis therapy for ulcerative colitis in three pediatric patients
    Kanako Mori
    Department of Pediatrics, Matsushita Memorial Hospital, Moriguchi Shi, Osaka, Japan
    J Pediatr Gastroenterol Nutr 39:549-51. 2004
  96. ncbi Kill the messenger of bad news?
    Jorge Amil Dias
    J Pediatr Gastroenterol Nutr 39:485-6. 2004
  97. ncbi Granulocyte and monocyte adsorptive apheresis in the treatment of active distal ulcerative colitis: a prospective, pilot study
    T Yamamoto
    Inflammatory Bowel Disease Centre, Yokkaichi Social Insurance Hospital, Yokkaichi, Mie, Japan
    Aliment Pharmacol Ther 20:783-92. 2004
    ..To assess safety and clinical efficacy of granulocyte and monocyte adsorptive apheresis for distal ulcerative colitis...
  98. ncbi [Granulocyte-apheresis in ocular Behçet's disease resistant to medical treatment]
    O García García
    Ciutat Sanitaria i Universitaria de Bellvitge, Barcelona, Spain
    Arch Soc Esp Oftalmol 79:335-40. 2004
    ..To assess the feasibility of granulocyte apheresis (GCAP) in patients with Ocular Behçet's Disease (BD) resistant to immunosuppressive therapy (prednisone, cyclosporin, azathyoprine or mycophenolate mofetil)...
  99. ncbi A novel, point-of-care test for lithium levels: description and reliability
    William M Glazer
    ReliaLAB, Inc, Basking Ridge, NJ, USA
    J Clin Psychiatry 65:652-5. 2004
    ..This article describes a novel instant blood test that will facilitate the routine monitoring process...
  100. ncbi Peripheral blood cell separation through surface-modified polyurethane membranes
    Akon Higuchi
    Department of Applied Chemistry, Seikei University, 3 1 Kichijoji kitamachi 3, Musashino, Tokyo 180 8633, Japan
    J Biomed Mater Res A 68:34-42. 2004
    ..The PU membranes showed different permeation and recovery ratios of specific cells depending on the functional groups attached to the membranes...
  101. ncbi Effects of erythrocytapheresis transfusion on the viscoelasticity of sickle cell blood
    George B Thurston
    Rheology Laboratory, Department of Mechanical Engineering, University of Texas at Austin, TX, USA
    Clin Hemorheol Microcirc 30:61-75. 2004
    ..This study confirms the beneficial effects on viscosity, elasticity, and relaxation time of erythrocytapheresis...

Research Grants7

  1. EOSINOPHIL AND BASOPHIL GRANULE PROTEINS
    Gerald Gleich; Fiscal Year: 2001
    ..Basophils from a patient with basophilic leukemia were obtained by cytapheresis and granules isolated...