Summary: Separation of one or more kinds of cells from whole blood with the return of other blood cell constituents to the patient or donor. This is accomplished with an instrument that uses centrifugation to separate the cells into different layers based on the differences in cell density (displacement) or drag coefficients in a current (elutriation). The procedure is commonly used in adoptive transfer to isolate NK cells, lymphocytes, or monocytes.
Publications144 found, 100 shown here
- [Indications of urgent plasma exchange and cytapheresis therapies--a review based on literature data and personal experience]Mihály Belák
Országos Gyógyintézeti Központ, Belgyógyászati és Geriatriai Klinika
Orv Hetil 147:1843-8. 2006..Similarly, urgent thrombocytapheresis should be administered above platelet numbers 1000 G/l, when there is concomitant thrombophilia or clinical symptoms of thrombostasis are present...
- Long-term prognosis of patients with ulcerative colitis treated with cytapheresis therapyTetsuro Takayama
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
J Crohns Colitis 7:e49-54. 2013Although accumulating studies in Japan show that cytapheresis (CAP) therapy is safe and effective for the induction of remission of moderate or severe ulcerative colitis (UC), the long-term prognosis of UC patients treated with CAP is ..
- Predicting the clinical response to cytapheresis in steroid-refractory or -dependent ulcerative colitis using contrast-enhanced ultrasonographyToshiki Yamaguchi
Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
Scand J Gastroenterol 44:831-7. 2009To evaluate the usefulness of transabdominal ultrasound (US), including contrast-enhanced ultrasonography (CEUS), in predicting the response to cytapheresis therapy in patients with steroid-refractory or -dependent ulcerative colitis (UC).
- Use of cellular and plasma apheresis in the critically ill patient: Part II: Clinical indications and applicationsMichael L Linenberger
Apheresis and Cellular Therapy, Seattle Cancer Care Alliance, Seattle, WA 98109, USA
J Intensive Care Med 20:88-103. 2005..Ongoing studies are investigating the potential utility of conventional plasma exchange, ex vivo plasma manipulation, and newer technologies for these and other disorders in severely ill patients...
- A new treatment for HCV-ulcerative colitis comorbidity intolerant to INF-alphaKoji Sawada
Am J Gastroenterol 98:228-9. 2003
- Granulocyte and monocyte adsorptive apheresis in a case with severe ulcerative colitis unresponsive to conventional medicationYasuo Suzuki
The Second Department of Internal Medicine, Chiba University School of Medicine, Chiba, Japan
J Clin Apher 18:40-2. 2003
- Why do some apheresis donors donate blood just once?J Ringwald
Department of Transfusion Medicine and Haemostaseology, University Hospital of Erlangen, D 91054 Erlangen, Germany
Vox Sang 93:354-62. 2007..We interviewed returning (RBD) and non-returning apheresis BDs (NRBD) of our university hospital-based BDS...
- Treatment of pyoderma gangrenosum associated with Crohn's diseaseToshihide Ohmori
Am J Gastroenterol 98:2101-2. 2003
- Guidelines for policies on alternatives to allogeneic blood transfusion. 1. Predeposit autologous blood donation and transfusionF E Boulton
National Blood Service, Southampton, UK
Transfus Med 17:354-65. 2007
- Use of cellular and plasma apheresis in the critically ill patient: part 1: technical and physiological considerationsMichael L Linenberger
Seattle Cancer Care Alliance, Seattle, WA 98109, USA
J Intensive Care Med 20:18-27. 2005..Part 2 of this series will deal with the clinical indications and applications for specific disorders that are most likely to affect patients in the intensive care unit...
- Exploring the feasibility of selective depletion of T lymphocyte subsets by whole blood immunoadsorption cytapheresisM Belak
Section of Hematology and Oncology, Department of Medicine, Boston University Medical Center, Boston, MA, USA
Clin Exp Immunol 150:477-86. 2007..It is possible that such apheresis techniques could achieve targeted forms of immunosuppression not possible with drugs or radiation...
- Ten-year follow-up of unrelated volunteer granulocyte donors who have received multiple cycles of granulocyte-colony-stimulating factor and dexamethasoneKaren Quillen
Department of Transfusion Medicine, Warren G Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
Transfusion 49:513-8. 2009..The short-term side effects of G-CSF are well studied, but the potential long-term effects of repeated G-CSF stimulation in unrelated volunteer granulocyte donors have not been reported...
- Evaluation of a new apheresis system for the collection of leukoreduced single-donor plateletsJürgen Zingsem
Department of Transfusion Medicine and Haemostaseology, University Hospital Erlangen, Erlangen, Germany
Transfusion 47:987-94. 2007..cell concentrates (WBCs) and leukoreduced single-donor platelet concentrates (SDPs) and performing therapeutic cytapheresis and plasmapheresis that might replace the Fresenius systems AS104 and AS.TEC 204...
- Cytapheresis in the treatment of cell-affected blood disorders and abnormalitiesBela Balint
Department of Experimental Hematology, Institute for Medical Research, Belgrade, Serbia and Montenegro
Transfus Apher Sci 35:25-31. 2006..The best clinical effect and long-term benefits were obtained using RBCX and antimalarial drugs in malaria patients who have had high-level parasitized-RBCs with multiorgan dysfunction...
- Immunoadsorption in dermatologyEnno Schmidt
Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, 23560, Lubeck, Germany
Arch Dermatol Res 302:241-53. 2010..effective and specific tool advantageous to plasmapheresis to remove immunoglobulin and immune complexes and in cytapheresis, immune cells from the circulation. IA was successfully used in various autoantibody-mediated diseases, e.g...
- Donor-derived hematopoietic stem cells in organ transplantation: technical aspects and hurdles yet to be clearedPatrick Herve
Establissement Français du Sang Borgogne Franche Comté, Besancon, France
Transplantation 75:55S-57S. 2003..The best yield of HSC is obtained from vertebral bodies. HSC harvesting by cytapheresis after cell mobilization with a cytokine such as granulocyte colony-stimulating factor should be preferred with ..
- CD34+ cells obtained from "good mobilizers" are more activated and exhibit lower ex vivo expansion efficiency than their counterparts from "poor mobilizers"Zoran Ivanovic
Aquitaine Limousin Branch of French Blood Institute and the University Victor Segalen Bordeaux 2, Bordeaux, France
Transfusion 50:120-7. 2010..We hypothesized that, apart from their mobilization from marrow to the blood, the response to G-CSF of CD34+ cells also includes activation of proliferation, metabolic activity, and proliferative capacity...
- Cytapheresis with a filter for selective removal of CD4+ T cells in experimental autoimmune encephalomyelitisShunya Nakane
Department of Neurology, Kawatana National Hospital, Nagasaki, Japan
Mult Scler 9:579-84. 2003..These results suggest that depletion of CD4+ T cells from the systemic circulation by extracorporeal treatment is a potentially useful strategy for treatment of acute phase and relapsing MS...
- Release of potential immunomodulatory factors during platelet storageFabrice Cognasse
EFS Auvergne Loire, Saint Etienne, France
Transfusion 46:1184-9. 2006..Recent studies have demonstrated that PLTs promote immunity and inflammation mainly by means of the CD40/CD40L pathway. Our objective was to describe the accumulation of cytokines in PLT concentrates during storage...
- Pharmaco-economic study of intensive chemotherapy with peripheral blood progenitor cell support for advanced breast cancerF Pinguet
Pharmacy Oncopharmacology Department, Val d Aurelle Anticancer Center, Parc Euromedecine, 34298 Montpellier Cedex 05, France
Oncol Rep 8:1013-7. 2001..We collected the data from the induction chemotherapy cycle (followed by cytapheresis) to the end of the hospitalisation for autograft...
- [The indication of steroid pulse therapy and apheresis therapy for multiple sclerosis]Satoru Ohji
Department of Neurology, Saitama Medical Center, Saitama Medical University
Nihon Rinsho 66:1127-32. 2008..Apheresis therapy includes plasmapheresis and cytapheresis, and plasmapheresis includes plasma exchange (PE) and immunoadsorption plasmapheresis (IAPP)...
- Treatment with cytapheresis for antineutrophil cytoplasmic antibody-associated renal vasculitis and its effect on anti-inflammatory factorsMidori Hasegawa
Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
Ther Apher Dial 9:297-302. 2005To evaluate the efficacy of cytapheresis for the treatment of rapidly progressive glomerulonephritis (RPGN) caused by myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA)-associated vasculitis, the renal prognosis and the ..
- Cytapheresis for the treatment of myeloperoxidase antineutrophil cytoplasmic autoantibody-associated vasculitis: a pilot study of 21 patientsMidori Hasegawa
Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
Ther Apher Dial 10:412-8. 2006..myeloperoxidase-antineutrophil cytoplasmic autoantibody (MPO-ANCA)-associated vasculitis were treated using cytapheresis. Of these, 17 were treated for glomerulonephritis and four were treated for pulmonary hemorrhage...
- Good manufacturing practices production of natural killer cells for immunotherapy: a six-year single-institution experienceDavid H McKenna
Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota Medical School, Minnesota 55108, USA
Transfusion 47:520-8. 2007..Herein is a report on the experience of clinical-scale, good manufacturing practices (GMPs) production of NK cells to treat advanced cancer...
- Lymphocytapheresis in the treatment of psoriasis vulgarisGiancarlo Maria Liumbruno
Apheresis Unit of Blood Bank and Transfusion Service, Hospital of Livorno, Livorno, Italy
J Clin Apher 21:158-64. 2006..Since cytapheresis has been widely applied to autoimmune disorders, emphasizing the recently reported results of granulocyte and ..
- Development of a rare cell fractionation device: application for cancer detectionHisham Mohamed
Wadsworth Center, New York State Department of Health, Albany, NY 12201, USA
IEEE Trans Nanobioscience 3:251-6. 2004..Devices designed to capture rare cells in peripheral circulation for downstream analysis will provide an important tool for diagnosis and treatment...
- [A study on cellular matrix via cell extraction from bovine pericardium]J Y Zhou
Division of Cardiac Valve, Fuwai Cardiovascular Institute, CAMS, PUMC, Beijing 100037, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 23:193-5. 2001..To obtain an acellular matrix from bovine pericardial tissue, as a scaffold for tissue engineering of heart valves or cardiovascular patching applications...
- Collection of MNCs with two cell separators for adoptive immunotherapy in patients with stage IV melanomaA Glaser
Department of Transfusion Medicine and Haemostaseology, University of Erlangen NYrnberg, Erlangen, Germany
Transfusion 41:117-22. 2001..MNCs for adoptive immunotherapy may be collected by leukocytapheresis with a cell separator...
- Quality of leucoreduced red blood cell concentrates: 5 years of follow-up in FranceA Chabanel
Etablissement Français du Sang, Paris, France
Vox Sang 94:41-7. 2008..Since 1998, prestorage leucoreduction of all cellular blood components has been made mandatory in France. The French blood service needed to follow the data on the quality of the blood components prepared by blood centres...
- [A contribution to a study of apoptosis of hematopoietic stem cells CD34+ by flow cytometry before and after cryopreservation]M Ben Nasr
Laboratoire d immunologie cellulaire et de cytométrie, centre national de transfusion sanguine de Tunis, 11, rue Djebel Lakdhar Bab Sa, BP 294 El Manar II 2092, Tunis, Tunisie
Transfus Clin Biol 15:91-7. 2008..But, we have noted a pronounced induction of apoptosis in peripheral mobilized blood compared to cytapheresis (after cryopreservation: 29.79% of apoptotic HSC CD34+ in peripheral mobilized blood but only 11...
- DNAM-1 and PVR regulate monocyte migration through endothelial junctionsNicolas Reymond
Institut National de la Santé et de la Recherche Médicale UMR599, Institut de Cancérologie de Marseille, IFR 137, 27 Bd Lei Roure, 13009 Marseille, France
J Exp Med 199:1331-41. 2004..Altogether, our results demonstrate that DNAM-1 regulates monocyte extravasation via its interaction with PVR expressed at endothelial junctions on normal cells...
- Efficacy of granulocytapheresis and leukocytapheresis for the treatment of microscopic polyangiitisMidori Hasegawa
Department of Nephrology, Fujita Health University School of Medicine, Aichi, Japan
Ther Apher Dial 8:212-6. 2004..All four lung hemorrhage episodes were ameliorated. We concluded that combined therapy of GCAP or LCAP and corticosteroids is effective for the treatment of RPGN and lung hemorrhage due to microscopic polyangiitis...
- A pilot study on the efficacy of ketorolac plus tramadol infusion combined with erythrocytapheresis in the management of acute severe vaso-occlusive crises and sickle cell painLucia De Franceschi
Haematologica 89:1389-91. 2004..Here we report a pilot study which combined balanced analgesia with tramadol plus ketorolac and erythrocytapheresis. Key words: sickle cell disease, therapeutic erythrocytapheresis, HbS, visual analog scale, vaso-occlusive crisis...
- Sensitive PCR method for the detection and real-time quantification of human cells in xenotransplantation systemsM Becker
, , 13092 Berlin, Germany
Br J Cancer 87:1328-35. 2002..4) Engraftment studies with blood stem cells originating from cytapheresis samples of tumour patients or from cord blood were undertaken in NOD/SCID mice in order to define conditions of ..
- A case report of a successful monochorionic diamniotic twin pregnancy in a patient affected by sickle cell disease treated with erythrocytapheresisSerena Motta
Department of Pediatrics, University of Milano Bicocca, San Gerardo Hospital, Monza, Italy
Ther Apher Dial 14:112-5. 2010....
- Prevalence of posterior subcapsular cataracts in volunteer cytapheresis donorsJanine A Clayton
Division of Epidemiology and Clinical Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 1863, USA
Transfusion 51:921-8. 2011..Granulocyte donors routinely receive dexamethasone orally before donation. Steroids may increase the risk of posterior subcapsular cataract (PSC) formation...
- High white blood cell concentration in the peripheral blood stem cell product can induce seizures during infusion of autologous peripheral blood stem cellsCarlos Bachier
Texas Transplant Institute, 7711 Louis Pasteur, San Antonio, TX, USA
Biol Blood Marrow Transplant 18:1055-60. 2012..Seizures during infusion of autologous PBSC in 3 of our patients prompted us to review our cell therapy and cytapheresis protocols and procedures...
- Persistence of lymphocyte function perturbations after granulocyte-colony-stimulating factor mobilization and cytapheresis in normal peripheral blood stem cell donorsCaroline Marmier-Savet
INSERM, Universite de Franche Comte, IFR133, and Etablissement Français du Sang, Bourgogne Franche Comté, UMR 645, Besancon, France
Transfusion 50:2676-85. 2010..In this respect, duration of G-CSF-induced perturbations has been less studied than short-term effects and needs to be evaluated...
- Ex vivo cytokine expansion of peripheral blood Ph-negative cells in chronic myeloid leukaemiaF X Mahon
Laboratoire de Greffe de Moelle, UMR CNRS 5540, FR60, Universite Victor Segalen Bordeaux 2, France
Leuk Lymphoma 32:151-7. 1998..Therefore ex vivo expansion of putatively normal hematopoietic progenitor cells from cytapheresis is feasible in CML.
- Cytapheresis in patients with severe ulcerative colitis after failure of intravenous corticosteroid: a long-term retrospective cohort studyKen Fukunaga
Division of Lower Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan
Gut Liver 3:41-7. 2009b>Cytapheresis (CAP) is a novel strategy for ulcerative colitis (UC). However, there is insufficient data on the long-term outcome of UC patients who achieve remission by CAP...
- Factors affecting short- and long-term effects of leukocyte removal therapy in active ulcerative colitisRyo Nakano
Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Saga, Japan
J Gastroenterol Hepatol 28:303-8. 2013..Leukocyte removal therapy (LRT) is recognized as an effective treatment for active ulcerative colitis (UC). In this study, factors associated with the efficacy and long-term effects of LRT were evaluated...
- Adverse events and problems in therapeutic hemapheresis. A report from the Swedish registryR Norda
Department of Transfusion Medicine and Immunohemotherapy, Orebro Medical Center Hospital, Sweden
Transfus Apher Sci 25:33-41. 2001..Since 1996 adverse events (AE) in therapeutic apheresis (TA) have been more extensively registered in Sweden. This report analyzes the extent and relation of AEs to procedures and diagnoses...
- First human application of a novel adsorptive-type cytapheresis module in patients with active ulcerative colitis: a pilot studyWolfgang Ramlow
Apheresis Center, Rostock, Germany
Ther Apher Dial 17:339-47. 2013..to evaluate the safety, tolerability, technical performance and clinical efficacy of a novel adsorptive-type cytapheresis module in patients with active ulcerative colitis...
- Administration of erythopoietin and granulocyte colony-stimulating factor in donor/recipient pairs to collect peripheral blood progenitor cells (PBPC) and red blood cell units for use in the recipient after allogeneic PBPC transplantationB Sautois
Department of Medicine, Division of Haematology, , , Belgium
Haematologica 86:1209-18. 2001....
- Multicomponent collection as of 2005M Valbonesi
Department of Immunohematology, San Martino University Hospital, Largo Rosanna Benzi 10, 16132 Genova, Italy
Transfus Apher Sci 32:287-97. 2005..In terms of donor acceptance it is our experience that, since 1989 no donor has refused MCC, consisting at least in the concurrent collection of plasma along with platelets, but also RBC and or a second unit of platelets...
- Diagnosis and treatment of hereditary hemochromatosis: an updatePushpjeet Kanwar
Liver Center for Excellence, Digestive Disease Institute, Virginia Mason Medical Center, Seattle, WA, USA
Expert Rev Gastroenterol Hepatol 7:517-30. 2013..Iron overload is being recognized to play a carcinogenic role in hepatocellular carcinoma and other cancers, possibly supporting iron depletion in these patients...
- [Evaluation of methods for collection of peripheral blood stem cells in children]Guomei Yin
The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
Zhejiang Da Xue Xue Bao Yi Xue Ban 42:350-4. 2013..To evaluate the methods for collection of peripheral blood stem cells (PBSC) in children...
- In vitro and in vivo evaluation of Adacolumn cytapheresis in healthy subjectsWolfgang Ramlow
Dialysis Group North, Rostock, Germany
J Clin Apher 20:72-80. 2005Adacolumn is a medical device for adsorptive cytapheresis. It has been developed for selective adsorption of granulocytes and monocytes from peripheral blood of patients with immune disorders, such as autoimmune diseases and chronic ..
- Automated processing of whole blood units: operational value and in vitro quality of final blood componentsMarisa Jurado
Community Transfusion Centre, Madrid, Spain
Blood Transfus 10:63-71. 2012..Interim platelet unit are pooled to produce a transfusable platelet unit. In this study the Atreus 3C system was evaluated and compared to the routine method with regards to product quality and operational value...
- Correction of hyperviscosity by apheresisMirjana Zarkovic
Hematology Oncology Division, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Semin Thromb Hemost 29:535-42. 2003..purification technique designed for the removal of either plasma (plasmapheresis) or cellular blood components (cytapheresis)...
- Analysis of 120 pediatric patients with nonmalignant disorders transplanted using unrelated plasma-depleted or -reduced cord bloodLawrence Petz
StemCyte International Cord Blood Center, Covina, California 91722, USA
Transfusion 52:1311-20. 2012..However, there are relatively limited data regarding outcomes of CB transplants using units processed by PDR...
- Transfusion immunomodulation--the case for leukoreduced and (perhaps) washed transfusionsKatie L Lannan
Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
Blood Cells Mol Dis 50:61-8. 2013..The present review will focus on two approaches, leukoreduction and saline washing, as means to reduce adverse transfusion outcomes...
- Safety of hematopoietic stem cell donation in glucose 6 phosphate dehydrogenase-deficient donorsF Pilo
Unità Operativa Ematologia e Centro Trapianti Midollo Osseo, Ospedale Oncologico di Riferimento Regionale Armando Businco, Cagliari, Italy
Bone Marrow Transplant 48:36-9. 2013..No difference was found in transplant outcome. From this retrospective analysis, we conclude that a G6PD-deficient but otherwise healthy volunteer can be selected as a HSC donor...
- Pilot clinical study of Adacolumn cytapheresis in patients with systemic lupus erythematosusHelmut Soerensen
Hospital Waldfriede, Berlin, Germany
Rheumatol Int 26:409-15. 2006The aim of this study is to investigate the clinical effects of cytapheresis using the Adacolumn system (selective removal of circulating monocytes and granulocytes by means of an extracorporeal type column) in patients with active ..
- Leucocytapheresis with Adacolumn enhances HCV-specific proliferative responses in patients infected with hepatitis C virus genotype 1Helmut M Diepolder
Institute for Immunology, University of Munich, Germany
J Med Virol 77:209-15. 2005..This study examined the effect of cytapheresis on the subsequent response to interferon/ribavirin treatment in patients infected with HCV...
- Short-term femoral catheter insertion: a promising alternative to consistently allow long-term erythrocytapheresis therapy in children with sickle cell anemiaMarie Billard
Hospices Civils de Lyon, Lyon, France
J Pediatr 162:423-6. 2013..We have successfully used short-term femoral catheter insertion, during a 6.5-year period for a total of 443 procedures, to perform long-term erythrocytapheresis in 18 consecutive children with sickle cell disease...
- [Extracorporeal photochemotherapy for treatment of clonal T cell proliferations]Joel Plumas
Unité mixte de therapie cellulaire et tissulaire, EFS Rhone Alpes, BP 35, 38701, La Tronche, France
Bull Cancer 90:763-70. 2003..Mononuclear cells are harvested by cytapheresis and reinfused to the patient after irradiation...
- [Therapeutic apheresis in multiple sclerosis]Kyoichi Nomura
Department of Neurology, Saitama Medical School
Nihon Rinsho 61:1388-95. 2003Therapeutic apheresis is divided in cytapheresis and plasmapheresis. And plasmapheresis(PP) is divided into three treatments, plasma exchange(PE), double filtration plasmapheresis(DFPP) and immunoadsorption plasmapheresis(IAPP)...
- Questionnaire based assessment of patients' acceptability of leukocytapheresis for the treatment of inflammatory bowel diseaseKazuko Nagase
Department of Internal Medicine, Division of Lower, Hyogo College of Medicine, Nishinomiya, Japan
Ther Apher Dial 17:490-7. 2013The aim of the present study was to assess patients' acceptance of therapeutic leukocytapheresis known as cytapheresis (CAP) for the treatment of an active flare of inflammatory bowel disease (IBD)...
- Utility of impedance cardiography for the detection of hemodynamic changes in stable patients with sickle cell diseaseBibhuti B Das
Department of Pediatrics, Division of Pediatric Cardiology, University of Texas Southwestern Medical Center, Dallas, TX 75235, USA
J Pediatr Hematol Oncol 34:336-9. 2012..The study sought to assess the potential utility of impedance cardiography (ICG) to detect hemodynamic changes after erythrocytapheresis in stable children with sickle cell disease (SCD)...
- Beyond dialysis: current and emerging blood purification techniquesBernd Stegmayr
Department of Public Health and Medicine, Umeå University and Division of Nephrology, Department of Internal Medicine, University Hospital, Umea, Sweden
Semin Dial 25:207-13. 2012..This comprises therapeutic apheresis (plasma exchange and cytapheresis), plasma adsorption, hemoperfusion, and the bio-artificial devices.
- Plasma level of granulocyte-colony stimulating factor during granulocyte and monocyte adsorptive apheresis in patients with ulcerative colitisHiroaki Takeda
Division of Endoscopy, Yamagata University Hospital, Yamagata, Japan
Hepatogastroenterology 56:348-51. 2009b>Cytapheresis with extra-corporeal circulation for ulcerative colitis is effective but its mechanisms are still unclear...
- Mobilization of peripheral blood progenitor cells after DHAP regimen with or without rituximab: a large multicenter comparative study in patients with malignant lymphomaRegis Peffault De Latour
Department of Clinical Hematology, Institut Curie, Paris, France
Leuk Lymphoma 48:897-904. 2007..The first cytapheresis was performed at day 10 in the R-DHAP group versus day 11 in the DHAP group...
- Peripheral blood stem cell recovery following early termination of apheresis due to hypotension in a 4.8-kg infantJessie Alex
DeGowin Blood Center, Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
J Clin Apher 24:120-1. 2009..If the procedure must be terminated early, sufficient PBSC may be recoverable from the blood in the apheresis instrument...
- Automated red cell collection--quality and valueJ F Harrison
National Blood Service, Colindale, London, UK
Transfus Med 16:155-64. 2006..The use of a double dose red cell product for transfusion to a single patient also confers benefit in terms of reduction in donor exposure...
- The impact of a regular erythrocytapheresis programme on the acute and chronic complications of sickle cell disease in adultsAnna Kalff
Department of Laboratory Haematology, Royal Melbourne Hospital, Vic, Australia
Br J Haematol 149:768-74. 2010..Regular ECP was demonstrated to be an effective, well-tolerated therapy for both acute and chronic complications of SCD in adults...
- Safety of 2-RBC donation: donor and recipient considerationsMark A Popovsky
Harvard Medical School and BethIsreal Deaconess Medical Center, Haemonetics Corporation, Braintree, MA 02184, USA
Transfus Apher Sci 35:3-4. 2006
- Regulatory T cells in patients with inflammatory bowel diseases treated with adacolumn granulocytapheresisEmilio Cuadrado
Immunology Unit, Hospital Donostia, P o doctor Begiristain s n, Donostia 20014, San Sebastian, Spain
World J Gastroenterol 14:1521-7. 2008....
- Are cell salvage and autologous blood transfusion safe in endonasal surgery?Shane Anderson
The University of Queensland, The Princess Alexandra Hospital, Department of Otolaryngology Head and Neck Surgery, Queensland Institute of Medical Research, Brisbane, Queensland, Australia
Otolaryngol Head Neck Surg 142:S3-6. 2010..In this literature review, we present the evidence for perioperative cell saver blood transfusion in potentially contaminated fields and the need for further investigation of its use in endonasal surgery...
- Bi-phasic CD34+ cell mobilization of a syngeneic donor during prolonged G-CSF deliveryS M Arnold
Division of Hematology and Oncology, Markey Cancer Center, University of Kentucky, Chandler Medical Center, Kentucky 40536, USA
Cytotherapy 1:119-22. 1999G-CSF administration over 10 days and neutrophil cytapheresis have been reported in the literature, but the kinetics of CD34+ cells in this situation is unclear.
- How I treat hemochromatosisPaul C Adams
University Hospital, University of Western Ontario, London, ON, Canada
Blood 116:317-25. 2010....
- [Episcleritis and erythema nodosum in a patient with ulcerative colitis]Satoshi Maekawa
Third Department of Internal Medicine, Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine
Nihon Shokakibyo Gakkai Zasshi 105:686-91. 2008..Although concurrent onset of episcleritis and erythema nodosum associated with UC is also extremely rare, clinical course in this case suggests a possible association among ulcerative colitis, episcleritis and erythema nodosum...
- Applications of platelet-rich fibrin matrix in facial plastic surgeryAnthony P Sclafani
Director of Facial Plastic Surgery, The New York Eye and Ear Infirmary, New York, New York 10003, USA
Facial Plast Surg 25:270-6. 2009..PRFM provides autologous, natural, but concentrated platelet growth factor release and stimulation of surrounding tissue. This article describes its use for cosmetic facial applications...
- Cytapheresis in inflammatory bowel diseases: current evidence and perspectivesSilvio Danese
Division of Gastroenterology, Istituto Clinico Humanitas, IRCCS in Gastroenterology, University of Milan, Rozzano Milan, Italy
Digestion 77:96-107. 2008....
- Mobilized allogeneic peripheral stem/progenitor cell apheresis with Spectra Optia v.5·0, a novel, automatic interface-controlled apheresis system: results from the first feasibility trialS Bräuninger
German Red Cross Blood Service Baden Wuerttemberg Hesse, Institute Frankfurt, and Institute for Transfusion Medicine and Immunohematology of Goethe University Medical Center, Frankfurt, Germany
Vox Sang 101:237-46. 2011....
- Stem cell harvesting protocol research in autologous transplantation setting: large volume vs. conventional cytapheresisBela Balint
Military Medical Academy, Institute of Transfusiology, Belgrade, Serbia
Vojnosanit Pregl 65:545-51. 2008..The basic goal of the study was to evaluate the influence of apheresis protocol (collection timing, processed blood volume and cell yield) upon the clinical outcome of transplantation...
- Conventional apheresis therapies: a reviewDavid M Ward
Division of Nephrology, University of California San Diego, San Diego, California, USA
J Clin Apher 26:230-8. 2011This article reviews advances in the scientific basis and medical practice of plasmapheresis and cytapheresis therapies...
- Comparison of the efficacy of granulocyte and monocyte/macrophage adsorptive apheresis and leukocytapheresis in active ulcerative colitis patients: a prospective randomized studyYasuhisa Sakata
Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Saga, Japan
Eur J Gastroenterol Hepatol 20:629-33. 2008..Recently, cytapheresis has emerged as a new treatment for patients with UC...
- Use of hemovigilance data to evaluate the effectiveness of diversion and bacterial detectionPierre Robillard
Institut National de Sante Publique du Quebec, Montreal, Canada
Transfusion 51:1405-11. 2011..We evaluated the effectiveness of these measures in Québec using hemovigilance data from January 2000 to December 2008...
- Differentiation of monocyte-derived dendritic cells under the influence of plateletsX D Nguyen
Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, Red Cross Blood Donation Service of Baden Wurttemberg Hessen, Germany
Cytotherapy 10:720-9. 2008..Platelets (Plt) are invariably found as a contaminant in the final monocytapheresis product. The aim of this study was to investigate DC differentiation under the influence of Plt with regard to their function and phenotype...
- Granulocytapheresis in the treatment of patients with active ulcerative colitisGiampaolo Bresci
U O Gastroenterologia, Azienda Ospedaliera Universitaria Pisana, Via A Della Spina, Pisa 1156125, Italy
Expert Rev Gastroenterol Hepatol 2:639-43. 2008..This article will review the clinical applications and issues concerning the use of granulocytapheresis in ulcerative colitis...
- Effects of cytapheresis on tumor necrosis factor receptor and on expression of CD63 in myeloperoxidase--antineutrophil cytoplasmic autoantibody-associated vasculitisMidori Hasegawa
Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
Ther Apher Dial 11:337-40. 2007To evaluate the therapeutic potential of cytapheresis in myeloperoxidase-antineutrophil cytoplasmic autoantibody (MPO-ANCA)-associated vasculitis, plasma levels of soluble tumor necrosis factor receptors (sTNFR1, sTNFR2) and the ..
- Partial remission of refractory RA after Adacolumn cytapheresis: a case reportL Bazzichi
Department of Internal Medicine, Division of Rheumatology, S Chiara Hospital, Pisa, Italy
Rheumatol Int 28:295-7. 2008..This improvement was maintained for over 2 months. At week 38, the patient was re-treated achieving again an ACR response >20...
- Assessment of corrected QT interval in sickle-cell disease patients who undergo erythroapheresisC Boga
Department of Hematology, Baskent University Faculty of Medicine, Ankara, Turkey
Transfus Med 17:466-72. 2007..Fifty percent QTc values returned to baseline after the procedure. The independent variables were not significantly associated with QTc interval. Exchange procedures can induce QTc prolongation in patients with SCD...
- Acute normovolemic red cell exchange for cardiopulmonary bypass in sickle cell diseaseG Shulman
Department of Pathology and Laboratory Medicine Blood Bank Division, University of Texas Medical Branch at Galveston 77555 0717, USA
Ann Thorac Surg 65:1444-6. 1998..Both techniques yielded fresh autologous plasma for use; sequestration yielded a platelet-pheresis product. Adequate postbypass hemostasis was demonstrated...
- Quantitative expression of adhesion molecules on granulocyte colony-stimulating factor-mobilized peripheral blood, bone marrow, and cord blood CD34+ cellsC Gigant
, LEMTA UMR CNRS 7563, , , France
J Hematother Stem Cell Res 10:807-14. 2001..Finally, the quantitative expression of the main receptors on CD34(+) cells explained cellular functions during the different steps of hematopoietic stem cells transplantation...
- Erythropoietin overdose treated with emergent erythropheresisRobert S Hoffman
New York City Poison Control Center, NY 10016, USA
Vet Hum Toxicol 44:157-9. 2002..This rare case of EPO overdose highlights the complications of essential erythrocytosis, with central nervous system, peripheral, and presumed mesenteric ischemia...
- Oxygen saturation and hemoglobin A content in patients with sickle cell disease undergoing erythrocytapheresisThomas P Nifong
Department of Pathology, Penn State Milton S Hershey Medical Center, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA
Ther Apher 6:390-3. 2002..We have shown that decreased baseline oxygen saturation in sickle cell disease is related to abnormal hemoglobin S levels, and oxygen saturation can be improved with erythrocytapheresis, independent of any change in the total hematocrit...
- Cytapheresis for the treatment of myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculitis: report of five casesMidori Hasegawa
Department of Nephrology, Fujita Health University School of Medicine, Aichi, Japan
Ther Apher 6:443-9. 2002..RPGN) and one patient with pulmonary hemorrhage due to MPO-ANCA-associated vasculitis were treated by cytapheresis. The prednisolone (PSL) dose was 0.28 +/- 0.15 mg/kg/day (mean +/- SD) (range 0.18-0.50 g/kg/day)...
- Do automated red cell exchanges relieve priapism in patients with sickle cell anemia?L J McCarthy
Department of Pathology and Laboratory Medicine, Indiana University School of Medicine and Indiana University Hospital, Indianapolis 46202 5283, USA
Ther Apher 4:256-8. 2000..One adult experienced resolution 8 h postexchange. However, he had a history of "stuttering" priapism. All required decompression procedures. Automated RBC exchanges were not effective in achieving detumescence or reducing pain...
- Quality of packed red blood cells and platelet concentrates collected by multicomponent collection using the MCS plus deviceG C Leitner
Department of Blood Group Serology and Transfusion Medicine, University of Vienna, Vienna, Austria
J Clin Apher 18:21-5. 2003..These results indicate less storage lesion in MCC-derived PRBCs compared to manually collected units and no compromise in the quality of MCC PCs obtained in the same apheresis procedure...
- [Therapeutic hemapheresis]Eli Taraldsrud
Immunologisk og transfusjonsmedisinsk avdeling
Tidsskr Nor Laegeforen 123:2439-42. 2003..This is the first survey of therapeutic hemapheresis in Norway. The purpose was to collect data from all Norwegian dialysis and blood units performing hemapheresis treatment and stem cell collection for comparison with Swedish data...
- Peripheral blood cell separation through surface-modified polyurethane membranesAkon Higuchi
Department of Applied Chemistry, Seikei University, 3 1 Kichijoji kitamachi 3, Musashino, Tokyo 180 8633, Japan
J Biomed Mater Res A 68:34-42. 2004..The PU membranes showed different permeation and recovery ratios of specific cells depending on the functional groups attached to the membranes...
- Effects of erythrocytapheresis transfusion on the viscoelasticity of sickle cell bloodGeorge B Thurston
Rheology Laboratory, Department of Mechanical Engineering, University of Texas at Austin, TX, USA
Clin Hemorheol Microcirc 30:61-75. 2004..This study confirms the beneficial effects on viscosity, elasticity, and relaxation time of erythrocytapheresis...
- Current topics on cytapheresis technologiesK Yamaji
Department of Internal Medicine and Rheumatology, Juntendo University, Tokyo, Japan
Ther Apher 5:287-92. 2001b>Cytapheresis has been investigated recently for the treatment of autoimmune related diseases, such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), multiple sclerosis, and so on...
- In vitro production of dendritic cells from human blood monocytes for therapeutic useL Garderet
INSERM U76, , Paris et Fontenay Aux Roses, France
J Hematother Stem Cell Res 10:553-67. 2001..The results obtained demonstrate that the experimental conditions we set up are easily applicable in clinical trials and lead to large numbers of well-defined DC. Clinical trials using DC already published will be discussed...
- Cell salvage and leucodepletionM H Cross
Department of Anaesthesia, The General Infirmary at Leeds, UK
Perfusion 16:61-6. 2001..This may be due to bradykinin production following platelet exposure to negatively charged leucocyte filters...
- Erythrocytapheresis limits iron accumulation in chronically transfused sickle cell patientsL M Hilliard
Department of Pediatrics, University of Alabama at Birmingham, USA
Am J Hematol 59:28-35. 1998..Erythrocytapheresis is a safe method of controlling Hb S levels and limiting or preventing iron load in chronically transfused sickle cell patients...
- Biocompatibility of a new cell separator studied by flow cytometry: analyses of platelet antigens during apheresis and storageK Gutensohn
Department of Transfusion Medicine Transplantation Immunology, University Hospital Eppendorf, University of Hamburg, Germany
Transfusion 39:742-7. 1999Alterations of platelet antigens are known to occur during cytapheresis and storage. These changes have been shown to be dependent on the biomaterials, techniques, and devices used...
- Long-term immune recovery after CD34+ immunoselected and unselected peripheral blood progenitor cell transplantation: a case-control studyL Laurenti
Divisione di Ematologia, Istituto Semeiotica Medica, Universita Cattolica Sacro Cuore, Largo A Gemelli 8, 00168 Rome, Italy
Haematologica 84:1100-3. 1999..We compared the long term immunologic recovery in two groups of patients submitted to CD34+ PBPCT or unselected autologous peripheral blood progenitor cell transplantation (uPBPCT)...
- Autologous stem cell transplantation for acute myeloid leukemia in first remissionC A Linker
University of California, San Francisco, USA
Biol Blood Marrow Transplant 6:50-7. 2000..Preliminary efficacy analysis is very encouraging, with outcomes that appear superior to those of conventional chemotherapy...