Genomes and Genes
Summary: Use of a device for the purpose of controlling movement of all or part of the body. Splinting and casting are FRACTURE FIXATION.
Publications210 found, 100 shown here
- Consumption of molecular hydrogen prevents the stress-induced impairments in hippocampus-dependent learning tasks during chronic physical restraint in miceKazufumi Nagata
Department of Biochemistry and Cell Biology, Institute of Development and Aging Sciences, Graduate School of Medicine, Nippon Medical School, Nakahara ku, Kawasaki, Japan
Neuropsychopharmacology 34:501-8. 2009..Chronic physical restraint stress to mice enhanced levels of oxidative stress markers, malondialdehyde and 4-hydroxy-2-nonenal, in the ..
- Chronic stress alters dendritic morphology in rat medial prefrontal cortexSusan C Cook
Department of Psychology, Indiana University, Bloomington, Indiana 47405, USA
J Neurobiol 60:236-48. 2004..This reorganization likely reflects functional changes in prefrontal cortex and may contribute to stress-induced changes in cognition...
- Chronic restraint stress induces changes in synapse morphology in stratum lacunosum-moleculare CA1 rat hippocampus: a stereological and three-dimensional ultrastructural studyH S Donohue
Department of Biological Sciences, The Open University, Walton Hall, Milton Keynes MK7 6AA, UK
Neuroscience 140:597-606. 2006..The data indicate a structural remodeling of excitatory axo-spinous synaptic connectivity in rat CA1 stratum lacunosum-moleculare as a result of chronic restraint stress...
- Constraint-induced movement therapy during early stroke rehabilitationCorwin Boake
Department of Physical Medicine, Baylor College of Medicine University of Texas Houston Medical School, Houston, TX, USA
Neurorehabil Neural Repair 21:14-24. 2007..Limited data are available about the effectiveness of early rehabilitation after stroke...
- Use of physical restraint in nursing homes: clinical-ethical considerationsC Gastmans
Center for Biomedical Ethics and Law, Catholic University of Leuven, Kapucijnenvoer 35, B 3000 Leuven, Belgium
J Med Ethics 32:148-52. 2006This article gives a brief overview of the state of the art concerning physical restraint use among older persons in nursing homes...
- Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrusKara Pham
Laboratory of Neuroendocrinology, Rockefeller University, New York, New York 10021, USA
Eur J Neurosci 17:879-86. 2003..These studies may help us understand the basis for hippocampal shrinkage and raise questions about the ultimate reversibility of the effects of chronic stress...
- Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor kappaB-mediated mechanismsJ L Madrigal
, Facultad de Medicina, Universidad Complutense, Madrid, Spain
J Neurochem 76:532-8. 2001....
- Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in miceDavid J Rademacher
Medical College of Wisconsin, Department of Pharmacology and Toxicology, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Neuropharmacology 54:108-16. 2008..These studies are consistent with the hypothesis that stress exposure alters endocannabinoid signaling in the brain and that alterations in endocannabinoid signaling occur during habituation to stress...
- Effects of chronic stress on hippocampal long-term potentiationConstantine Pavlides
The Rockefeller University, New York, New York 10021, USA
Hippocampus 12:245-57. 2002..Furthermore, they suggest that chronic stress produces changes in the input-output relationship in the hippocampal trisynaptic circuit which could affect information flow through this structure...
- Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvementN Sousa
Department of Anatomy, Porto Medical School, Alameda Prof Hernani Monteiro, 4200 319, Porto, Portugal
Neuroscience 97:253-66. 2000..We conclude that there is an intimate relationship between corticosteroid levels, hippocampal neuritic structure and hippocampal-dependent learning and memory...
- Physical restraint use in a Korean ICUEunha Choi
Seoul National University Hospital, Seoul, Korea
J Clin Nurs 12:651-9. 2003....
- 'It's part of the job, but it spoils the job': a phenomenological study of physical restraintStuart Bigwood
Mental Health Services, Canterbury District Health Board, Christchurch, New Zealand
Int J Ment Health Nurs 17:215-22. 2008This paper examines mental health nurses' experiences of physical restraint in an acute inpatient psychiatric setting using Van Manen's descriptive hermeneutic phenomenological methodology...
- Influence of physical restraint on unplanned extubation of adult intensive care patients: a case-control studyLi Yin Chang
Taichung Veterans General Hospital, Taichung, Taiwan
Am J Crit Care 17:408-15; quiz 416. 2008..Various physical restraints have been used to prevent patients from removing their endotracheal tubes. However, physical restraint not only does not consistently prevent injury but also may be a safety hazard to patients.
- An audit of physical restraint and seclusion in five psychogeriatric admission wards in Victoria, AustraliaDaniel O'Connor
Int J Geriatr Psychiatry 19:797-9. 2004
- Psychiatric inpatients' perceptions of positive and negative aspects of physical restraintWai Tong Chien
The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, CUHK, Shatin, NT, SAR, China
Patient Educ Couns 59:80-6. 2005..study explored the experiences and feelings of psychiatric inpatients concerning their first encounter with physical restraint. Its purpose was to determine whether restraint has any other effects, other than the intended one of ..
- The conceptualization of physical restraint as a nursing-sensitive adverse outcome in acute care psychiatric treatment settingsAngela M Gerolamo
Center for Health Outcomes and Policy Research, University of Pennsylvania, Philadelphia, PA
Arch Psychiatr Nurs 20:175-85. 2006The occurrence of physical restraint episodes in psychiatric settings is a major public health issue because the therapeutic utility of this form of behavior control has not been substantiated empirically...
- Repeated stress induces dendritic spine loss in the rat medial prefrontal cortexJason J Radley
Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
Cereb Cortex 16:313-20. 2006..Dendritic atrophy and spine loss may be important cellular features of stress-related psychiatric disorders where the PFC is functionally impaired...
- Responding to a violent incident: physical restraint or anger management as therapeutic interventionsD M Lewis
Queen Anne s Gate, London, UK
J Psychiatr Ment Health Nurs 9:57-63. 2002..The importance of this paper lies in reorienting forensic clinicians away from the perceived ideologies of physical restraint as a primary intervention, moving towards the productive use of anger management.
- Deep venous thrombosis and pulmonary embolism following physical restraintS B Laursen
University Clinic of Neuroanaesthesia, The Neuroscience Center, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Acta Psychiatr Scand 111:324-7; discussion 327. 2005We describe a case of deep venous thrombosis (DVT) and pulmonary embolism (PE) following the use of physical restraint in a patient with a diagnosis of acute delusional psychotic disorder.
- A program to reduce use of physical restraint in psychiatric inpatient facilitiesJessica A Jonikas
Department of Psychiatry, University of Illinois at Chicago, 104 South Michigan Avenue, Suite 900, Chicago, IL 60603, USA
Psychiatr Serv 55:818-20. 2004The authors describe a program to reduce the use of physical restraint on three psychiatric units of a university hospital...
- A review of physical restraint minimization in the acute and residential care settingsDavid Evans
Department of Clinical Nursing, University of Adelaide, Adelaide, South Australia, Australia
J Adv Nurs 40:616-25. 2002The objective of this review was to investigate physical restraint minimization in acute and residential care settings...
- The effects of chronic stress on hippocampal morphology and function: an evaluation of chronic restraint paradigmsKatie J McLaughlin
Department of Psychology, Arizona State University, Tempe, AZ 85287 1104, USA
Brain Res 1161:56-64. 2007....
- Chronic stress alters synaptic terminal structure in hippocampusA M Magarinos
The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Proc Natl Acad Sci U S A 94:14002-8. 1997....
- Mild, short-term stress alters dendritic morphology in rat medial prefrontal cortexSarah M Brown
Department of Psychology, Indiana University, Bloomington, IN 47405, USA
Cereb Cortex 15:1714-22. 2005..Thus, the stress-induced dendritic changes in medial prefrontal cortex occur rapidly, and in response to a mild stressor...
- Stressor categorization: acute physical and psychological stressors elicit distinctive recruitment patterns in the amygdala and in medullary noradrenergic cell groupsC V Dayas
School of Biomedical Sciences, Department of Physiology and Pharmacology, University of Queensland, Brisbane, Australia 4072
Eur J Neurosci 14:1143-52. 2001..Moreover, the present data suggest that the neural activation footprint that is left in the brain by stressors can be used to determine the category to which they have been assigned by the brain...
- Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axisSachin Patel
Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Endocrinology 145:5431-8. 2004....
- Oxytocin attenuates stress-induced c-fos mRNA expression in specific forebrain regions associated with modulation of hypothalamo-pituitary-adrenal activityRichard J Windle
University Research Centre for Neuroendocrinology, University of Bristol, Bristol Royal Infirmary, Bristol BS2 8HW, United Kingdom
J Neurosci 24:2974-82. 2004..These data show that central oxytocin attenuates both the stress-induced neuroendocrine and molecular responses of the HPA axis and that the dorsal hippocampus, LSV, and PVN constitute an oxytocin-sensitive forebrain stress circuit...
- Increased sensitivity to restraint stress and novelty-induced emotionality following long-term, high dose cannabinoid exposureMatthew N Hill
Department of Psychology, University of British Columbia, Vancouver, BC, Canada V6T 1Z4
Psychoneuroendocrinology 31:526-36. 2006..This interaction was not seen in the basolateral amygdala. Together, these findings suggest that chronic high dose, but not low dose, cannabinoid administration may result in increased emotionality and sensitization of the stress axis...
- Reproducibility of patient positioning for fractionated extracranial stereotactic radiotherapy using a double-vacuum techniqueMeinhard Nevinny-Stickel
Department of Radiotherapy Radiooncology, University Hospital Innsbruck, Austria
Strahlenther Onkol 180:117-22. 2004..A fixation system based on double-vacuum technology is presented which can be used for conventional as well as hypofractionated stereotactic extracranial radiotherapy...
- The use of physical restraint in critical careKaren Hine
Intensive Care Unit, County Hospital, Lincoln, UK
Nurs Crit Care 12:6-11. 2007..The use of physical restraint appears to be a useful and simple solution to prevent this treatment interference...
- Re-designing state mental health policy to prevent the use of seclusion and restraintKevin Ann Huckshorn
National Technical Assistance Center, National Association of State Mental Health Program Directors NAMSHPD, Alexandria, VA 22314, USA
Adm Policy Ment Health 33:482-91. 2006..Endorsed by the State Mental Health Directors, July 13, 1999). (NASMHPD 1999, NASMHPD Position Statement on Seclusion and Restraint. Alexandria, VA: National Technical Assistance Center for State Mental Health Planning.)...
- A review of agitation in mental illness: treatment guidelines and current therapiesStephen R Marder
Department of Psychiatry, David Geffen School of Medicine at the University of California Los Angeles, VISN 22 Mental Illness Research, Education, and Clinical Center, Los Angeles, Calif, USA
J Clin Psychiatry 67:13-21. 2006..Agitation is an important therapeutic target in the acute and/or emergent setting, as well as for longer-term care of patients with psychiatric illness...
- The medial prefrontal cortex differentially regulates stress-induced c-fos expression in the forebrain depending on type of stressorHelmer F Figueiredo
Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, Ohio 45267 0559, USA
Eur J Neurosci 18:2357-64. 2003..Taken together, this study indicates that the medial prefrontal cortex differentially regulates cellular activation of specific stress-related brain regions, thus exerting stressor-dependent inhibition of the HPA axis...
- Regulation of CART mRNA by stress and corticosteroids in the hippocampus and amygdalaRichard G Hunter
Laboratory of Neuroendocrinology, Rockefeller University, New York, New York, NY 10021, USA
Brain Res 1152:234-40. 2007..Our data establish that CART expression is regulated by stress in a regionally and time specific manner and that CART is regulated by corticosteroid actions in the hippocampus...
- Lipid peroxidation and total radical-trapping potential of the lungs of rats submitted to chronic and sub-chronic stressR L Torres
Departamento de Bioquimica, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 90035 003 Porto Alegre, RS, Brasil
Braz J Med Biol Res 37:185-92. 2004..48 +/- 0.42; stressed: 3.65 +/- 0.16, P < 0.05). We conclude that different stressors induce different effects on the oxidative status of the organism...
- The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunctionAngel Ponferrada
Servicio de Aparato Digestivo, Hospital General Universitario Gregorio Maranon, Madrid
Gastroenterology 132:1791-803. 2007..Psychological stress has been implicated in the clinical course of several gastrointestinal diseases, but the mechanisms implicated and the effects of stress on the normal colon are not yet fully understood...
- Acute stress modulates the histamine content of mast cells in the gastrointestinal tract through interleukin-1 and corticotropin-releasing factor release in ratsHelene Eutamene
Institut National de la Recherche Agronomique, Department of Neurogastroenterology and Nutrition, 180 chemin de Tournefeuille, BP 3, 31931 Toulouse, France
J Physiol 553:959-66. 2003..C.V. CRF administration. These results suggest that in rats acute stress increases colonic mast cell histamine content. This effect is mediated by the release in cascade in the brain first of IL-1 and secondly of CRF...
- L-NAME prevents anxiety-like and depression-like behavior in rats exposed to restraint stressS Sevgi
Department of Pharmacology and Clinical Pharmacology, Istanbul Faculty of Medicine, Istanbul University, Capa Istanbul, Turkey
Methods Find Exp Clin Pharmacol 28:95-9. 2006..These data lead to the conclusion that stress and NO seem to be involved in the generation of anxiety and depression...
- Norepinephrine release in medial amygdala facilitates activation of the hypothalamic-pituitary-adrenal axis in response to acute immobilisation stressS Ma
Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas Health Science Center, San Antonio, TX 78229 3900, USA
J Neuroendocrinol 17:22-8. 2005....
- Morphological changes in the hippocampal CA3 region induced by non-invasive glucocorticoid administration: a paradoxA M Magarinos
Department of Biology, Arizona State University, Tempe, USA
Brain Res 809:314-8. 1998....
- Development and testing of tools to assess physical restraint useNancy Edwards
School of Nursing, Department of Epidemiology and Community Medicine, University of Ottawa, Ontario, Canada
Worldviews Evid Based Nurs 3:73-85. 2006..There is a need for a reliable and valid instrument that is feasible for use in these settings to rapidly assess physical restraint use.
- Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdalaSachin Patel
Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Neuropsychopharmacology 30:497-507. 2005....
- Antioxidant potential of vitamins A, E and C in modulating oxidative stress in rat brainS M Kashif R Zaidi
Department of Biochemistry, Faculty of Life Sciences, A M U 202002, Aligarh, India
Clin Chim Acta 340:229-33. 2004..The efficacy of antioxidant vitamins A, E and C alone and in combination was also evaluated in modulating inherent antioxidant system in stressed rats...
- Use of physical restraints with cognitively impaired nursing home residentsJan P H Hamers
Associate Professor, Department of Health Care Studies, Section of Nursing Science, Universiteit Maastricht, Maastricht, The Netherlands
J Adv Nurs 45:246-51. 2004The aim of the study was to examine the prevalence of physical restraint use in cognitively impaired nursing home residents, the manner in which restraints are used, reasons for using them, and relationships between residents' ..
- The mentally ill and social exclusion: a critical examination of the use of seclusion from the patient's perspectiveDave Holmes
University of Ottawa, Faculty of Health Sciences, School of Nursing Ottawa, Ontario, Canada
Issues Ment Health Nurs 25:559-78. 2004..A need for modifying the institutional culture surrounding seclusion and transforming nursing practices are discussed as are future research endeavours...
- The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/nitrosative mediators in brain after acute stress in ratsBorja García-Bueno
Department of Pharmacology, Faculty of Medicine, Universidad Complutense Madrid, 28040, Madrid, Spain
Psychopharmacology (Berl) 180:513-22. 2005....
- Immediate active mobilization versus immobilization for opposition tendon transfer in the handSantosh Rath
LEPRA HOINA Leprosy Reconstructive Surgery Unit, Muniguda, Orissa, India
J Hand Surg Am 31:754-9. 2006..To test the hypothesis that immediate postoperative active mobilization of the hand after opposition tendon transfer will achieve outcomes similar to those of the standard practice of cast immobilization...
- SAMHSA's commitment to eliminating the use of seclusion and restraintCharles G Curie
Substance Abuse and Mental Health Services Administration, 1 Choke Cherry Road, Rockville, Maryland 20857, USA
Psychiatr Serv 56:1139-40. 2005
- Description of an advanced practice nursing consultative model to reduce restrictive siderail use in nursing homesLaura M Wagner
Baycrest Centre for Geriatric Care, Kunin Lunenfeld Applied Research Unit, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
Res Nurs Health 30:131-40. 2007..Findings suggest that an APN consultation model can effectively be implemented through comprehensive, individualized assessment without incurring substantial costs to the nursing home...
- Minimizing the use of restrictive devices in dementia patients at risk for fallingElizabeth Capezuti
John A Hartford Foundation Institute for Geriatric Nursing, Division of Nursing, Steinhardt School of Education, New York University, 246 Greene Street, 6th Floor, New York, NY 10003 6677, USA
Nurs Clin North Am 39:625-47. 2004..New institutional models of care discouraging routine use of restrictive devices also will foster innovative solutions to clinical problems associated with dementia...
- Pharmacological and biochemical studies on the possible role of nitric oxide in stress adaptation in ratsAnbrin Masood
Department of Pharmacology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi 110007, India
Eur J Pharmacol 493:111-5. 2004..The results are suggestive of the role of nitric oxide in stress adaptation and this may be due to the effects of restraint stress on brain NOS activity...
- A systematic review of the safety and effectiveness of restraint and seclusion as interventions for the short-term management of violence in adult psychiatric inpatient settings and emergency departmentsLouise Nelstrop
Royal College of Nursing Institute, Radcliffe Infirmary, Oxford, UK
Worldviews Evid Based Nurs 3:8-18. 2006..The review was undertaken as part of the development process for a national guideline on the short-term management of disturbed/violent behaviour in adult psychiatric inpatient settings and emergency departments in the United Kingdom...
- Short-term effects of an educational intervention on physical restraint use: a cluster randomized trialAnna R Huizing
Department of Health Care Studies, Section of Nursing Science, Maastricht University, Maastricht, The Netherlands
BMC Geriatr 6:17. 2006..The aim of this study was to investigate the short-term effects of an educational intervention on the use of physical restraints in psycho-geriatric nursing home residents...
- Differences in period prevalence of the use of physical restraints in elderly inpatients of European hospitals and nursing homesOscar J de Vries
J Gerontol A Biol Sci Med Sci 59:M922-3. 2004
- [Effectiveness of a multifactorial intervention to reduce physical restraints in nursing home residents with dementia]P Koczy
Klinik für Geriatrische Rehabilitation, Robert Bosch Krankenhaus Stuttgart, Akademisches Lehrkrankenhaus der Universität Tübingen, Auerbachstrasse 110, 70376 Stuttgart, Germany
Z Gerontol Geriatr 38:33-9. 2005..The aim of the study is to develop an evidence-based model for a knowledge transfer project to implement minimum restraint environments in LTC...
- Why do we use physical restraints in the elderly?J P H Hamers
Universiteit Maastricht, Department of Health Care Studies, Section of Nursing Science, 6200 MD Maastricht, The Netherlands
Z Gerontol Geriatr 38:19-25. 2005....
- The effect of staff training on the use of restraint in dementia: a single-blind randomised controlled trialI Testad
Stavanger University Hospital, Psychiatric Clinic, Stavanger Norway
Int J Geriatr Psychiatry 20:587-90. 2005..Use of restraint amongst institutionalised elderly with dementia and problem behaviour not only remains widespread, but also appears to be accepted as inevitable...
- Effects of a rostral motor cortex lesion on primary motor cortex hand representation topography in primatesKathleen M Friel
Department of Molecular and Integrative Physiology, Landon Center on Aging, and Smith Mental Retardation Research Center, University of Kansas Medical Center, Kansas City, KS, USA
Neurorehabil Neural Repair 21:51-61. 2007..The goal of the present study was to determine if rehabilitative training has similar effects on functional topography of the spared M1 after rostral versus previously reported caudal M1 lesions...
- Inhibition of restraint stress-induced neural and behavioural activation by endogenous cannabinoid signallingSachin Patel
Department of Pharmacology and Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Eur J Neurosci 21:1057-69. 2005....
- Overexpression of agouti protein and stress responsiveness in miceR B Harris
Pennington Biomedical Research Center, 6400 Perkins Road, 70808, Baton Rouge, LA, USA
Physiol Behav 73:599-608. 2001..Thus, the increased stress responsiveness in BAPa mice may be a developmental compensation for chronic inhibition of melanocortin receptors...
- Body weight gain and diurnal differences of corticosterone changes in response to acute and chronic stress in ratsS Retana-Marquez
Department of Reproductive Biology, Universidad Autonoma Metropolitana Iztapalapa, Mexico City, Mexico
Psychoneuroendocrinology 28:207-27. 2003....
- Chronic stress and sex differences on the recall of fear conditioning and extinctionSarah E Baran
Department of Psychology, Arizona State University, Tempe, AZ 85287 1104, United States
Neurobiol Learn Mem 91:323-32. 2009....
- Perceptions regarding the use of physical restraints with elderly persons: comparison of Israeli health care nurses and social workersPerla Werner
Department of Gerontology, Faculty of Social Welfare and Health Studies, University of Haifa, Mt Carmel, Haifa 31905, Israel
J Interprof Care 16:59-68. 2002....
- Feasibility of randomized controlled trials on seclusion and mechanical restraintJan Bergk
Department of Psychiatry I, University of Ulm, Weingartshofe str 2, 88214 Ravensburg, Germany
Clin Trials 5:356-63. 2008..The least restrictive alternative is recommended. Evidence about what kind of intervention is least restrictive is only scarcely available. Up to now, no randomized controlled trial (RCT) on this subject has been conducted...
- Coercive procedures and facilities in Swiss psychiatryIan Needham
Kantonale Psychiatric Hospital, CH 9500 Wil, Switzerland
Swiss Med Wkly 132:253-8. 2002..Coercive measures in psychiatry,although in many cases effective in violence management and injury reduction, have been criticised from a consumerist point of view...
- Attitudes of Dutch, German and Swiss nursing staff towards physical restraint use in nursing home residents, a cross-sectional studyJan P H Hamers
Maastricht University, The Netherlands
Int J Nurs Stud 46:248-55. 2009....
- Perceptions of older people who have experienced physical restraintR Gallinagh
University of Ulster, Jordanstown and United Hospitals, Antrim, Northern Ireland
Br J Nurs 10:852-9. 2001..However, the negative comments of the patients were more prevalent and their responses were categorized in terms of institutional control, ritualised care, entrapment and discomfort, and possible alternatives...
- Side rail use and bed-related fall outcomes among nursing home residentsElizabeth Capezuti
School of Nursing and the Emory Center for Health in Aging, Emory University, Atlanta, GA 30329, USA
J Am Geriatr Soc 50:90-6. 2002To analyze the effect of physical restraint reduction on nighttime side rail use and to examine the relationship between bilateral side rail use and bed-related falls/injuries among nursing home residents.
- Involvement of dynorphin in immobilization stress-induced antinociception in the mouseH W Suh
Hallym University, College of Medicine, Institute of Natural Medicine, Department of Pharmacology, Chunchon, Kangwon Do, 200 702, South
Eur Neuropsychopharmacol 10:407-13. 2000..Our results suggest that supraspinally and spinally located dynorphin appears to be involved in the production of immobilization stress-induced antinociception via stimulating kappa-opioid receptors...
- Effect of repeated stress on novelty-induced antinociception in ratsI L Torres
Departamento de Bioquimica, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil
Braz J Med Biol Res 34:241-4. 2001..These results suggest that repeated restraint stress induces an alteration in the nociceptive response, perhaps as a result of an alteration in endogenous opioids in these animals...
- Stress upregulates TPH1 but not TPH2 mRNA in the rat dorsal raphe nucleus: identification of two TPH2 mRNA splice variantsNashat Abumaria
Clinical Neurobiology Laboratory, German Primate Center, Leibniz Institute for Primate Research, Kellnerweg 4, Gottingen, 37077, Germany
Cell Mol Neurobiol 28:331-42. 2008..Expression of both TPH2 splice variants is not affected by stress, neither in DRN nor in the PiG. These data indicate that TPH1 in the serotonergic neurons of the DRN might be relevant for stress-induced psychopathologies...
- Adaptation to prolonged or repeated stress--comparison between rat strains showing intrinsic differences in reactivity to acute stressF S Dhabhar
Laboratory of Neuroendocrinology, The Rockefeller University, New York, N Y 10021, USA
Neuroendocrinology 65:360-8. 1997..These differences under prolonged or repeated stress conditions may consequently magnify the behavioral and immunological differences observed between strains under basal as well as challenged conditions...
- Patient injury and physical restraint devices: a systematic reviewDavid Evans
Department of Clinical Nursing, University of Adelaide, Adelaide, Australia
J Adv Nurs 41:274-82. 2003To investigate physical restraint-related injuries. Areas of interest were the prevalence of injury, types of injuries, risk of sustaining an injury and specific restraint devices associated with injury.
- An updated national survey on seclusion and restraintW B Crenshaw
Family Service and Guidance Center of Topeka, KS 66606, USA
Psychiatr Serv 48:395-7. 1997..Small positive correlations were found between seclusion and restraint and between the proportion of beds occupied by patients committed as criminally insane and the use of restrictive procedures...
- Consequences of an intervention to reduce restrictive side rail use in nursing homesElizabeth Capezuti
John A Hartford Foundation Institute for Geriatric Nursing, New York University College of Nursing, New York, New York 10003, USA
J Am Geriatr Soc 55:334-41. 2007..A secondary question explored the association between restrictive side rail reduction and bed-related falls...
- Chronic restraint stress during early Theiler's virus infection exacerbates the subsequent demyelinating disease in SJL mice: II. CNS disease severityErin E Young
Department of Psychology, College of Liberal Arts, Texas A and M University College Station, TX 77843, United States
J Neuroimmunol 220:79-89. 2010..These findings indicate that RS during early TMEV infection increases CNS lesion formation during the late phase and suggest that the effects of RS are sex-dependent...
- Restraint stress fails to render C57BL/6 mice susceptible to Theiler's virus-induced demyelinationAndrew J Steelman
Department of Veterinary Integrative Biosciences, College of Liberal Arts, Texas A and M University, College Station, Tex, USA
Neuroimmunomodulation 17:109-19. 2010..Although its cause is unknown, multiple factors are thought to influence both the onset and exacerbation of the disease, including both genetic background as well as environmental factors...
- A cluster-randomized trial of an educational intervention to reduce the use of physical restraints with psychogeriatric nursing home residentsAnna R Huizing
Health Care and Nursing Science, Maastricht University, Maastricht, The Netherlands
J Am Geriatr Soc 57:1139-48. 2009..To investigate the effects of an educational intervention on the use of physical restraints with psychogeriatric nursing home residents...
- Neuroendocrine responses to an emotional stressor: evidence for involvement of the medial but not the central amygdalaC V Dayas
Department of Physiology, University of Queensland, Brisbane, QLD 4072, Australia
Eur J Neurosci 11:2312-22. 1999....
- Acute stress causes mucin release from rat colon: role of corticotropin releasing factor and mast cellsI Castagliuolo
Division of Gastroenterology, Beth Israel Hospital, Harvard Medical School, Boston 02215, USA
Am J Physiol 271:G884-92. 1996..We conclude that CRF released during immobilization stress increases colonic transit via a neuronal pathway and stimulates colonic mucin secretion via activation of neurons and mast cells...
- Preventing the use of physical restraints on residents newly admitted to psycho-geriatric nursing home wards: a cluster-randomized trialAnna R Huizing
Department of Health Care Studies, Section of Nursing Science, Maastricht University, The Netherlands
Int J Nurs Stud 46:459-69. 2009..Although there is an urgent need for restraint-free care, the number of randomized clinical trials on preventing or reducing physical restraints has been limited...
- Restraint stress modulates virus specific adaptive immunity during acute Theiler's virus infectionAndrew J Steelman
Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 4458, USA
Brain Behav Immun 23:830-43. 2009..As T cells mediate viral clearance in this model, our data support the hypothesis that stress-induced immunosuppression may provide a mechanism for enhanced viral persistence within the CNS...
- Restraint use among nursing home residents: cross-sectional study and prospective cohort studyGabriele Meyer
Unit of Health Sciences and Education, University of Hamburg, Hamburg, Germany
J Clin Nurs 18:981-90. 2009....
- The effect of physical restraints on fall rates in older adults who are institutionalizedK S Dunn
Oakland University, School of Nursing, Rochester, MI 48309-4401, USA
J Gerontol Nurs 27:40-8. 2001..Removing physical barriers from older adults and allowing freedom of movement may decrease the severity of injury sustained in a fall...
- Does risk adjustment of the CMS quality measures for nursing homes matter?Dana B Mukamel
University of California Irvine, Center for Health Policy Research, Irvine, California 92697 5800, USA
Med Care 46:532-41. 2008..The Centers for Medicare and Medicaid Services (CMS) publish a report card for nursing homes with 19 clinical quality measures (QMs). These measures include minimal risk adjustment...
- Adverse effects associated with physical restraintWanda K Mohr
Rutgers University, College of Nursing, Newark, New Jersey, USA
Can J Psychiatry 48:330-7. 2003..This paper reviews the literature concerning actual and potential causes of deaths proximal to the use of physical restraint.
- Physical restraint initiation in nursing homes and subsequent resident healthJohn Engberg
RAND Corporation, Pittsburgh, PA, USA
Gerontologist 48:442-52. 2008It is widely believed that physical restraint use causes mental and physical health decline in nursing home residents. Yet few studies exist showing an association between restraint initiation and health decline...
- Sustained release of corticosterone in rats affects reactivity, but does not affect habituation to immobilization and acoustic stimuliMarit A C Tanke
Graduate School of Behavioral and Cognitive Neuroscience, University of Groningen, University Center of Psychiatry, University Medical Center Groningen, The Netherlands
Life Sci 83:135-41. 2008..This implies that altered HPA-axis function in depressed patients may not be causally related to stress coping, but instead may influence the course of the disorder...
- Changes in hypothalamic-pituitary-adrenal function, body temperature, body weight and food intake with repeated social stress exposure in ratsS Bhatnagar
Department of Anaesthesiology, Abranson Building Ste 402, Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
J Neuroendocrinol 18:13-24. 2006....
- Prolactin-releasing peptide is a potent mediator of stress responses in the brain through the hypothalamic paraventricular nucleusT Mera
Department of Physiology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Kitakyushu 807 8555, Japan
Neuroscience 141:1069-86. 2006..These results suggest that prolactin-releasing peptide is a potent and important mediator of the stress response in the brain through the hypothalamic paraventricular nucleus...
- Intracerebroventricular administration of corticotrophin-releasing hormone receptor antagonists produces different effects on hypothalamic pituitary adrenal responses to novel restraint depending on the stress history of the animalC Vining
Department of Anesthesiology, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Neuroendocrinol 19:198-207. 2007..In summary, these results indicate that manipulations of the CRH receptor have different effects on HPA activity depending on the stress history of the animal...
- Effect of voluntary wheel running on circadian corticosterone release and on HPA axis responsiveness to restraint stress in Sprague-Dawley ratsSergiu Fediuc
School of Kinesiology and Health Science, Faculty of Pure and Applied Science, York University, 4700 Keele St, Toronto, ON, Canada M3J 1P3
J Appl Physiol 100:1867-75. 2006....
- Limited brain diffusion of the glucocorticoid receptor agonist RU28362 following i.c.v. administration: implications for i.c.v. drug delivery and glucocorticoid negative feedback in the hypothalamic-pituitary-adrenal axisA B Francis
Campus Box 345, University of Colorado at Boulder, Boulder, CO 80309, USA
Neuroscience 141:1503-15. 2006....
- Corticosterone can act at the posterior paraventricular thalamus to inhibit hypothalamic-pituitary-adrenal activity in animals that habituate to repeated stressAzra Jaferi
Department of Psychology, University of Michigan, Ann Arbor, 48109, USA
Endocrinology 147:4917-30. 2006....
- [Effect of Jiawei Sini Decoction on HPA function of rats with restraint psychological stress]Ya fei Shi
Guangzhou University of Chinese Medicine, Guangzhou 510405, China
Zhong Yao Cai 31:88-91. 2008..To observe the effect of Jiawei Sini Decoction (JWSND) on HPA function of rats with restraint psychological stress and the pathway of thymus immunosuppressive function...
- Daily cocaine self-administration under long-access conditions augments restraint-induced increases in plasma corticosterone and impairs glucocorticoid receptor-mediated negative feedback in ratsJohn R Mantsch
Department of Biomedical Sciences, Box 1881, Marquette University, Milwaukee, WI 53201 1881, USA
Brain Res 1167:101-11. 2007..The findings suggest that cocaine use produces persistent changes in individual responsiveness to stressors that may contribute to the addiction process...
- The nociceptin/orphanin FQ antagonist UFP-101 differentially modulates the glucocorticoid response to restraint stress in rats during the peak and nadir phases of the hypothalamo-pituitary-adrenal axis circadian rhythmJ D Leggett
Department of Anatomy, University of Bristol, Southwell Street, Bristol, UK
Neuroscience 147:757-64. 2007....
- Chronic nicotine self-administration augments hypothalamic-pituitary-adrenal responses to mild acute stressHao Chen
Department of Pharmacology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Neuropsychopharmacology 33:721-30. 2008..Furthermore, chronic nicotine SA selectively cross-sensitized the HPA response to a novel stressor. These observations suggest that nicotine may selectively increase the HPA response to stressors in human smokers...
- Estrogen potentiates adrenocortical responses to stress in female ratsHelmer F Figueiredo
Department of Psychiatry, University of Cincinnati, Genome Research Institute, Psychiatry North, ML 0506, Bldg 43, 2nd Floor, 2170 East Galbraith Road, Reading, OH 45237 0506, USA
Am J Physiol Endocrinol Metab 292:E1173-82. 2007..These results suggest that enhanced adrenal sensitive to ACTH is an important physiological mechanism mediating E(2)-related glucocorticoid hypersecretion in stressed females...
- Antagonism of corticotrophin-releasing factor receptors in the fourth ventricle modifies responses to mild but not restraint stressJoanna R Miragaya
Department of Foods and Nutrition, Dawson Hall, University of Georgia, Athens, GA 30602, USA
Am J Physiol Regul Integr Comp Physiol 295:R404-16. 2008..Hindbrain CRFR do not appear to influence stress-induced corticosterone release in RRS rats...
- Characteristics of behavior and stress reactivity of the hypophyseal-adrenocortical system in rats with prenatal inhibition of testosterone metabolismS G Pivina
I P Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034 St Petersburg, Russia
Neurosci Behav Physiol 37:53-8. 2007....
- Physical Restraints and Therapy Disruption in HospitalsAnn Minnick; Fiscal Year: 2005..death, fracture, aspiration and delirium) have been reported to be the direct or indirect result of physical restraint (PR)...
- Stress and CRF Signaling in Alzheimer?s Disease PathogenesisPaul E Sawchenko; Fiscal Year: 2012..We have found that acute exposure to an emotional stressor (physical restraint) elicits robust increases in tau phosphorylation (tau-P) in mouse hippocampus, a pivotal structure in ..
- Interaction Behaviors Effect on Nursing Care Quality of Older Adults in the ICUMarci Lee Nilsen; Fiscal Year: 2012..the association between interaction behaviors and nursing care quality indicators (sedation use and level, physical restraint use, pain management, and unplanned device disruption);3) psychometrically evaluate an interaction behavior ..
- Patient Care Outcomes at End-of-Life for Older Adults in ICUJennifer B Seaman; Fiscal Year: 2013..to end-of-life (EOL) care;these include unrelieved pain, ICU-acquired pressure ulcers, heavy sedation and physical restraint use...
- CMS Nonpayment for Nosocomial Injury and Risk of Falls in HospitalsRonald I Shorr; Fiscal Year: 2010..The tertiary aims of this study are to determine: 3. The relationship between physical restraint use and the risk of patient falls at the level of the: 3a. nursing unit, and 3b. patient, and 4...
- CONSEQUENCES OF PHYSICAL RESTRAINTSNicholas Castle; Fiscal Year: 2004..BY APPLICANT): In nursing home inspections conducted by state licensure and certification agencies, a physical restraint is defined as a device that is attached and cannot be easily removed by the resident which restricts freedom ..
- USE OF PHYSICAL RESTRAINTS FOR ELDERLY PATIENTSLorraine Mion; Fiscal Year: 1991..b>Physical restraint is a common but increasingly controversial practice in the United States...
- DOT and fMRI Studies of Visual Perception and ImageryGiorgio Ganis; Fiscal Year: 2005..important for healthy infants and young children, in which fMRI cannot easily be used without extreme physical restraint measures (e.g...
- Improving Communication with NonSpeaking ICU PatientsMARY HAPP; Fiscal Year: 2007..Primary covariates include severity of illness, level of consciousness, and physical restraint use...
- NEURODEVELOPMENTAL INSULTS AND SCHIZOPHRENIARUSSELL POLAND; Fiscal Year: 2001..the investigator proposes a characterization of the effects of prenatal stress in the form of repeated daily physical restraint of pregnant dams...
- HOSPTIAL STAFFING, PHYSICAL RESTRAINT & PATIENT OUTCOMESEILEEN SULLIVAN MARX; Fiscal Year: 2002..It is hypothesized that hospital nurse staffing and organization affect the rate of physical restraint use, and that such use is associated with poorer outcomes at discharge...
- LONG-TERM SENSITIZATION AFTER ACUTE STRESSORSSEYMOUR ANTELMAN; Fiscal Year: 1993..For example, a single exposure to either physical restraint of amphetamine (AM) can augment an animal's behavioral response to subsequent AM given one month later...
- A TREATMENT FOR EXCESS MOTOR DISABILITY IN THE AGEDEdward Taub; Fiscal Year: 2007..abstract_text> ..
- Randomized Controlled Trial of Pediatric CI TherapyEdward Taub; Fiscal Year: 2006..abstract_text> ..
- The Influence of Staff Turnover on QualityNicholas Castle; Fiscal Year: 2007..We propose to use five well-accepted indicators of care quality in nursing homes. These are the rates of physical restraint use, urethral catheterization, pressure ulcers, psychoactive medication use, and persistent pain...
- EXAMINING NURSING HOME COMPARENicholas Castle; Fiscal Year: 2005..abstract_text> ..
- Staffing Characteristics of Nursing Homes and QualityNicholas Castle; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Effects of Aging on Cancellation TasksVICTOR MARK; Fiscal Year: 2002..The findings will provide normative data for future research to determine whether cancellation tests may be sensitive to functional decline in aging and neurologic disorders. ..
- Cognitive Screening for CI Therapy after StrokeVICTOR MARK; Fiscal Year: 2004....
- INCIDENT REPORTING IN NURSING HOMESNicholas Castle; Fiscal Year: 2008..This information will further our development of a standardized incident reporting mechanism recommended by the Institute of Medicine and others. [unreadable] [unreadable] [unreadable]..
- Sex Differences in Hippocampal Synaptic Protein & mRNARussell Romeo; Fiscal Year: 2005..Finally, additional experiments will provide novel information on how exposure to steroid hormones during prenatal development sexually differentiates the ability of estrogen to affect hippocampal synapses. ..
- Mental Practice Dosing and Mechanisms in StrokeStephen Page; Fiscal Year: 2006..Identification of MP mechanisms of action and optimal dosing is fundamental to cost-effective, appropriate implementation of this promising, CAM, mind-body technique, and will enable a subsequent MP clinical trial. ..
- Prevention of Neck Injuries in Older Adults During Rear Motor Vehicle CollsionsPAUL IVANCIC; Fiscal Year: 2009..The proposed project will provide important research-based data that may form the basis for future safety standards and help to decrease the frequency and severity of neck injuries in older adults, thus benefiting society. ..
- EXTREMITY CONSTRAINT INDUCED THERAPY EVALUATION (EXCITE)Steven Wolf; Fiscal Year: 2004..Primary outcome measures are a laboratory motor function test and amount of extremity use in the real world setting. Changes in psychosocial functioning will also be measured. ..
- Social Stress, GC Resistance and Innate ImmunityJohn Sheridan; Fiscal Year: 2008..4. Determine the effect of SDR on innate immunity and susceptibility to infectious disease. This study will elucidate the mechanisms of immunoregulation and host resistance to disease that are altered by social stress. ..
- CRF2 Receptor Modulation of Colonic Response to StressMILLION MULUGETA; Fiscal Year: 2006..abstract_text> ..
- Stress Response Differences in Females: Estradiol's RoleMartha Faraday; Fiscal Year: 2003..abstract_text> ..
- MOLECULAR BIOLOGY OF NOREPINEPHRINE BIOSYNTHESISEsther Sabban; Fiscal Year: 2006..These findings will contribute to the development of new strategies to prevent the harmful maladaptive changes in catecholamine neurotransmission, while enhancing its beneficial adaptive aspects ..
- Sympathetic Ganglia: New Target for ACTH with StressEsther Sabban; Fiscal Year: 2008..abstract_text> ..
- Phox2a/2b Function in the Mature Locus Coeruleus.Meng Yang Zhu; Fiscal Year: 2008..This information may greatly facilitate the development of meaningful, testable therapeutic intervention for aging, PD, and AD. [unreadable] [unreadable] [unreadable]..
- Improved Methodology: A Factorial Survey StudyRuth Ludwick; Fiscal Year: 2003..Descriptive statistics, regression, and a repeated measures within subjects ANOVA will be used to analyze the data. ..
- ALTERED ETHANOL EFFECTS ON OSTEOCALCIN NULL MUTANT MICEPatricia Patterson Buckendahl; Fiscal Year: 2006....
- NASD Academic ED Collaborative - UC San DiegoTheodore Chan; Fiscal Year: 2004..UCSD ED investigators will be responsible for following up on difficult to reach) patients. Local data and survey results will be submitted to the R-25 and R-21 sites for analysis. ..
- Significance of Stress-Induced Hippocampal AtrophyCHERYL CONRAD; Fiscal Year: 2006..abstract_text> ..
- Development and control of repetitive leg movements during embryonic developmentNINA BRADLEY; Fiscal Year: 2008..We will accelerate the time to hatch by incubating eggs in constant light and delay time to hatch by incubating eggs in constant dark. [unreadable] [unreadable] [unreadable]..
- Stress Sensitization of CRF-Induced Withdrawal BehaviorsGeorge Breese; Fiscal Year: 2009..New treatment strategies could emerge from such knowledge ..
- SYMPATHETIC NEURAL FUNCTION AND GLUCOCORTICOIDSDEBORAH SCHEUER; Fiscal Year: 2001..The results will provide fundamental new knowledge of the mechanisms of glucocorticoid-mediated modulation of arterial pressure regulation. ..
- Nursing Homes Response to Quality Indictors PublicationDana Mukamel; Fiscal Year: 2008..Statistical regression techniques will be used to analyze the data and test specific hypotheses. ..
- NEUROPHARMACOLOGY OF PRIMATE COGNITIONMICHAEL TAFFE; Fiscal Year: 2002..abstract_text> ..
- Neuroscience Center for Biomedical Research ExcellenceFrancis W Flynn; Fiscal Year: 2010....
- Multilevel Intervention to Improve Nursing Home OutcomesMarilyn Rantz; Fiscal Year: 2009..Similarly, we will observe processes of care delivery before, during and after the multilevel intervention to describe the adoption of the care delivery strategies recommended in the intervention. ..
- Songbird Neurogenomics InitiativeDavid F Clayton; Fiscal Year: 2010..Moreover, the approach here may serve as a model for doing science on a community scale, embracing individual initiative but coordinating efforts to achieve a larger synergy. ..
- Legacy Intervention Family Enactment (LIFE): An Effectiveness TrialRebecca Allen; Fiscal Year: 2009....
- Dysregulation of Brain Stress Systems and of RelapseFriedbert Weiss; Fiscal Year: 2008....
- Corticotropin Releasing Factor-Norepinephrine Interactions in Stress & DepressionADRIAN DUNN; Fiscal Year: 2008..The results should establish a model and indicate the nature of the cerebral structures involved, so that we can subsequently test the feed-forward hypothesis [unreadable] [unreadable]..
- 2008 Genes and Behavior Gordon Research ConferenceDavid Clayton; Fiscal Year: 2007..This conference will promote progress towards this understanding by bringing together experts working with a variety of organismal models, human populations and technical approaches. [unreadable] [unreadable] [unreadable]..
- Genetic Analysis of Stress Response on EtOH SensitivityClarissa Parker; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- User adjustable support surfaces for wheelchair comfortDouglas Hobson; Fiscal Year: 2004..In sub-task 4, these results will be compiled and submitted for an STTR phase II work continuation. All of these sub-tasks will assist in meeting the overall goal ..
- Stress Effects on an Animal Model of Autoimmune DiseaseCHRISTABEL WELSH; Fiscal Year: 2005..Clarifying how environmental stressors influence an individual's vulnerability to autoimmune disease may increase our understanding of diseases such as multiple sclerosis and thus lead to the development of therapeutic regimens. ..
- EXPERIENCE DEPENDENT CHANGES IN THE BRAINDavid Clayton; Fiscal Year: 2003..This program of basic research has fundamental applicability to issues of human health and disease, including various psychiatric conditions and learning disorders. ..
- 5-HT1A RECEPTOR/G PROTEIN COUPLING AND ADAPTATIONEmanuel Meller; Fiscal Year: 2003..abstract_text> ..
- COGNITIVE EFFECTS OF ALCOHOL IN PERI-ADOLESCENT MONKEYSMICHAEL TAFFE; Fiscal Year: 2006..This exploratory study will provide evidence regarding the risks posed to cognition by heavy alcohol drinking in the peri-adolescent period. ..
- DST and Suicide PredictionElizabeth Young; Fiscal Year: 2003....
- Mineralocorticoid-R Control of HPA Stress ResponseTHADDEUS PACE; Fiscal Year: 2003..And finally, the role of MR in controlling HPA responding will be examined after a stressor has been experienced repeatedly, a situation previously shown to increase the number of brain MR. ..
- WAGES: Workplace Activity for Employee Goal SettingRODNEY DISHMAN; Fiscal Year: 2006..The project will implement and rigorously evaluate a multilevel physical activity intervention that has potential for broad application to workplace health promotion. ..
- Collaborative Care of Depression in Nursing HomesMark Snowden; Fiscal Year: 2006....
- Task Practice Schedules to Enhance Recovery after StrokeNicolas Schweighofer; Fiscal Year: 2006..The hypothesis is that subjects with mild deficits benefit most from expanded variable practice, whereas subjects with moderate deficits benefit most from massed practice schedules. [unreadable] [unreadable]..
- FUNCTIONAL NEUROANATOMY OF MOVEMENT DISORDERSLucy Brown; Fiscal Year: 2006..The studies may provide clues to the function of the gene huntingtin, and define a target for therapeutic strategies. In addition, these studies address the plastic and proliferative capacity of the adult brain. ..
- PRENATAL ALCOHOL EXPOSURE AND PREMATURE AGINGROBERT MC GIVERN; Fiscal Year: 2002..A potential relationship between prenatal exposure to subteratogenic levels of ethanol and an accelerated rate of aging has broad implications for NIH with regard to treatment, health education, and clinical services. ..
- FETAL ALCOHOL EXPOSURE--NEUROIMMUNE INTERACTIONSAnna Taylor; Fiscal Year: 2001....
- VERY EARLY CONSTRAINT-INDUCED MOVEMENT THERAPY:STROKEAlexander Dromerick; Fiscal Year: 2004....
- Effects of Short Chain Fatty Acids on Colonic MotilityToku Takahashi; Fiscal Year: 2009..These results may provide a rational explanation as to how low concentrations of luminal SCFAs and stress contributes to the pathogenesis of diarrhea-predominant irritable bowel syndrome (IBS). ..
- CAREER DEVELOPMENT AWARD IN PEDIATRIC PSYCHOPHARMACOLOGYAndres Martin; Fiscal Year: 2004..abstract_text> ..