autologous transplantation

Summary

Summary: Transplantation from another site in or on the body of the individual receiving it.

Top Publications

  1. pmc Salvage regimens with autologous transplantation for relapsed large B-cell lymphoma in the rituximab era
    Christian Gisselbrecht
    Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010 Paris, France
    J Clin Oncol 28:4184-90. 2010
  2. ncbi Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial
    Eriko Tateishi-Yuyama
    Department of Medicine II and Cardiovascular Centre, Kansai Medical University, Osaka, Japan
    Lancet 360:427-35. 2002
  3. ncbi Iliac crest bone graft harvest donor site morbidity. A statistical evaluation
    J C Banwart
    Section of Orthopedic Surgery, University of Kansas Medical Center, Kansas City, USA
    Spine (Phila Pa 1976) 20:1055-60. 1995
  4. doi Bortezomib as induction before autologous transplantation, followed by lenalidomide as consolidation-maintenance in untreated multiple myeloma patients
    Antonio Palumbo
    Divisione di Ematologia dell Universita di Torino, Azienda Ospedaliero Universitaria San Giovanni Battista, Via Genova 3, 10126 Torino, Italy
    J Clin Oncol 28:800-7. 2010
  5. ncbi Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial
    Gunnar Knutsen
    Department of Orthopaedic Surgery, University Hospital Tromsø, 9038 Tromsø, Norway
    J Bone Joint Surg Am 86:455-64. 2004
  6. pmc Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation
    Mari Dezawa
    Department of Anatomy and Neurobiology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    J Clin Invest 113:1701-10. 2004
  7. ncbi Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium
    Kohji Nishida
    Department of Ophthalmology, Osaka University Medical School, Suita, Osaka, Japan
    N Engl J Med 351:1187-96. 2004
  8. ncbi Three-, 6-, and 12-month results of autologous transplantation of mononuclear bone marrow cells in patients with acute myocardial infarction
    Jaroslav Meluzin
    1st Department of Internal Medicine Cardioangiology, St Anna Hosp, MU Czech Republic
    Int J Cardiol 128:185-92. 2008
  9. doi Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe 2009
    P Ljungman
    Department of Haematology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Bone Marrow Transplant 45:219-34. 2010
  10. pmc Intense T cell depletion followed by autologous bone marrow transplantation for severe multiple sclerosis
    J P A Samijn
    Department of Neurology, MS Centre ErasErasmus MC, Postbox 2040, 3000 CA Rotterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 77:46-50. 2006

Research Grants

Detail Information

Publications228 found, 100 shown here

  1. pmc Salvage regimens with autologous transplantation for relapsed large B-cell lymphoma in the rituximab era
    Christian Gisselbrecht
    Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010 Paris, France
    J Clin Oncol 28:4184-90. 2010
    ..Salvage regimens have never been compared; their efficacy in the rituximab era is unknown...
  2. ncbi Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial
    Eriko Tateishi-Yuyama
    Department of Medicine II and Cardiovascular Centre, Kansai Medical University, Osaka, Japan
    Lancet 360:427-35. 2002
    ..We investigated efficacy and safety of autologous implantation of bone marrow-mononuclear cells in patients with ischaemic limbs because of peripheral arterial disease...
  3. ncbi Iliac crest bone graft harvest donor site morbidity. A statistical evaluation
    J C Banwart
    Section of Orthopedic Surgery, University of Kansas Medical Center, Kansas City, USA
    Spine (Phila Pa 1976) 20:1055-60. 1995
    ..The findings suggest that procedural refinements of limiting subcutaneous dissection and providing layered tension-free incision closure may improve results...
  4. doi Bortezomib as induction before autologous transplantation, followed by lenalidomide as consolidation-maintenance in untreated multiple myeloma patients
    Antonio Palumbo
    Divisione di Ematologia dell Universita di Torino, Azienda Ospedaliero Universitaria San Giovanni Battista, Via Genova 3, 10126 Torino, Italy
    J Clin Oncol 28:800-7. 2010
    PURPOSE To evaluate the effect of bortezomib as induction therapy before autologous transplantation, followed by lenalidomide as consolidation-maintenance in myeloma patients...
  5. ncbi Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial
    Gunnar Knutsen
    Department of Orthopaedic Surgery, University Hospital Tromsø, 9038 Tromsø, Norway
    J Bone Joint Surg Am 86:455-64. 2004
    ..The objective of the present study was to compare autologous chondrocyte implantation with microfracture in a randomized trial. We are not aware of any previous randomized studies comparing these methods...
  6. pmc Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation
    Mari Dezawa
    Department of Anatomy and Neurobiology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    J Clin Invest 113:1701-10. 2004
    ..This study shows that a population of neuronal cells can be specifically generated from MSCs and that induced cells may allow for a neuroreconstructive approach...
  7. ncbi Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium
    Kohji Nishida
    Department of Ophthalmology, Osaka University Medical School, Suita, Osaka, Japan
    N Engl J Med 351:1187-96. 2004
    ..We studied the use of autologous oral mucosal epithelial cells as a source of cells for the reconstruction of the corneal surface...
  8. ncbi Three-, 6-, and 12-month results of autologous transplantation of mononuclear bone marrow cells in patients with acute myocardial infarction
    Jaroslav Meluzin
    1st Department of Internal Medicine Cardioangiology, St Anna Hosp, MU Czech Republic
    Int J Cardiol 128:185-92. 2008
    ..There are only few data on long-term effectiveness of the stem cell therapy...
  9. doi Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe 2009
    P Ljungman
    Department of Haematology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Bone Marrow Transplant 45:219-34. 2010
    ..The introduction of alternative therapies, such as imatinib for CML, has challenged well-established indications. An updated report with revised tables and operating definitions is presented...
  10. pmc Intense T cell depletion followed by autologous bone marrow transplantation for severe multiple sclerosis
    J P A Samijn
    Department of Neurology, MS Centre ErasErasmus MC, Postbox 2040, 3000 CA Rotterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 77:46-50. 2006
    ..Certain stem cell transplantation procedures might slow down inflammatory pathology in multiple sclerosis (MS)...
  11. pmc Yttrium-90 ibritumomab tiuxetan doses calculated to deliver up to 15 Gy to critical organs may be safely combined with high-dose BEAM and autologous transplantation in relapsed or refractory B-cell non-Hodgkin's lymphoma
    Jane N Winter
    Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Clin Oncol 27:1653-9. 2009
    ..radiation-absorbed dose (RAD) to critical organs delivered by yttrium-90 ((90)Y) ibritumomab tiuxetan in combination with high-dose carmustine, etoposide, cytarabine, and melphalan (BEAM) chemotherapy with autologous transplantation.
  12. pmc Idiotype-pulsed antigen-presenting cells following autologous transplantation for multiple myeloma may be associated with prolonged survival
    Martha Q Lacy
    Division of Hematology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Am J Hematol 84:799-802. 2009
    ..This approach warrants further investigation to confirm this and define the role of vaccine therapy in myeloma...
  13. doi Poor mobilization of hematopoietic stem cells-definitions, incidence, risk factors, and impact on outcome of autologous transplantation
    Patrick Wuchter
    Department of Internal Medicine V, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    Biol Blood Marrow Transplant 16:490-9. 2010
    ..mobilization" (PM), we have analyzed the efficiency of mobilization in patients intended to receive autologous transplantation at our center in the past 6 years...
  14. doi A prospective, randomized clinical study of osteochondral autologous transplantation versus microfracture for the treatment of osteochondritis dissecans in the knee joint in children
    Rimtautas Gudas
    Kaunas University of Medicine, Kaunas, Lithuania
    J Pediatr Orthop 29:741-8. 2009
    The aim of this study was to compare the outcomes of the arthroscopic mosaic-type osteochondral autologous transplantation (OAT) and microfracture (MF) procedures for the treatment of osteochondritis dissecans (OCD) defects of the femoral ..
  15. doi Impact of mobilization and remobilization strategies on achieving sufficient stem cell yields for autologous transplantation
    Iskra Pusic
    Washington University School of Medicine, Siteman Cancer Center, St Louis, Missouri 63110, USA
    Biol Blood Marrow Transplant 14:1045-56. 2008
    ..study we analyzed clinical records of 1834 patients who underwent stem cell mobilization for autologous transplantation from November 1995 to October 2006 at the Washington University in St. Louis...
  16. ncbi Safety analysis and improved cardiac function following local autologous transplantation of CD133(+) enriched bone marrow cells after myocardial infarction
    Hossein Ahmadi
    Tehran Heart Center, Tehran University of Medical Sciences, Tehran, I R Iran
    Curr Neurovasc Res 4:153-60. 2007
    ..Moreover, these cells might restore tissue viability and improve perfusion of the infarcted myocardium, suggesting that they may induce myogenesis as well as angiogenesis...
  17. pmc Magnetically labeled mesenchymal stem cells after autologous transplantation into acutely injured liver
    Xiao Lei Shi
    Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, No 321 Zhongshan Road, Nanjing, Jiangsu Province, China
    World J Gastroenterol 16:3674-9. 2010
    ..To evaluate tracking of magnetically labeled mesenchymal stem cells (MSCs) after intraportal transplantation...
  18. ncbi In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/
    Anthony H Goldstone
    North London Cancer Network, University College London Hospitals, London, United Kingdom
    Blood 111:1827-33. 2008
    ..the role of allogeneic transplantation for adults with acute lymphoblastic leukemia (ALL) and compare autologous transplantation with standard chemotherapy...
  19. ncbi Repair of cartilage defect in the rabbit with cultured mesenchymal stem cells from bone marrow
    G I Im
    Hallym University, Chunchon, Korea
    J Bone Joint Surg Br 83:289-94. 2001
    ..These findings suggest that repair of cartilage defects can be enhanced by the implantation of cultured mesenchymal stem cells...
  20. pmc Treatment of focal articular cartilage defects in the knee: a systematic review
    Robert A Magnussen
    Vanderbilt Orthopaedic Institute, 4200 Medical Center East, 1215 21st Avenue South, Suite 4200, Nashville, TN, 37232 8774, USA
    Clin Orthop Relat Res 466:952-62. 2008
    ..A large prospective trial investigating these techniques with the addition of a control group would be the best way to definitively address the clinical questions...
  21. doi Autologous transplantation of endothelial progenitor cells attenuates acute lung injury in rabbits
    Chen Fuh Lam
    Department of Anesthesiology, National Cheng Kung University College of Medicine and Hospital, Tainan, Taiwan
    Anesthesiology 108:392-401. 2008
    ..Here, the authors present the first study demonstrating the therapeutic potential of EPCs in a rabbit model of ALI/ARDS...
  22. ncbi Catheter-based autologous bone marrow myocardial injection in no-option patients with advanced coronary artery disease: a feasibility study
    Shmuel Fuchs
    Cardiovascular Research Institute, MedStar Research Institute, Washington Hospital Center, 110 Irving Street NW, 4B 1, Washington, DC 20010, USA
    J Am Coll Cardiol 41:1721-4. 2003
    ..We conducted a pilot study to evaluate the feasibility of transendocardial delivery of autologous bone marrow (ABM) strategy in patients with severe symptomatic chronic myocardial ischemia not amenable to conventional revascularization...
  23. ncbi High dose sequential chemotherapy with autologous transplantation versus dose-dense chemotherapy MegaCEOP as first line treatment in poor-prognosis diffuse large cell lymphoma: an "Intergruppo Italiano Linfomi" randomized trial
    Umberto Vitolo
    Ematologia, Azienda Ospedaliera S Giovanni Battista, Corso Bramante 88, 10126 Turin, Italy
    Haematologica 90:793-801. 2005
    ....
  24. doi Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy
    Nathalie Cartier
    INSERM UMR745, University Paris Descartes, 75279 Paris, France
    Science 326:818-23. 2009
    ..Thus, lentiviral-mediated gene therapy of hematopoietic stem cells can provide clinical benefits in ALD...
  25. ncbi Second allogeneic transplantation after failure of first autologous transplantation
    J P Radich
    Clinical Research Division of the Fred Hutchinson Cancer Research Center University of Washington School of Medicine, 98109, USA
    Biol Blood Marrow Transplant 6:272-9. 2000
    ..allogeneic bone marrow transplantations (BMTs) in 59 patients aged 1-57 years who relapsed after initial autologous transplantation. Patients received a second transplantation for recurrent acute myeloid leukemia (AML) (n = 24), acute ..
  26. doi Autologous transplantation of EPCs encoding FGF1 gene promotes neovascularization in a porcine model of chronic myocardial ischemia
    Shu yan Chen
    Department of Cardiology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, No 1665 Kong Jiang Road, Shanghai 200092, China
    Int J Cardiol 135:223-32. 2009
    ..fibroblast growth factor (sp-FGF1) gene transfer may achieve functional improvement of EPCs and that autologous transplantation of sp-FGF1-modified EPCs can facilitate neovascularization in a porcine model of chronic myocardial ..
  27. ncbi Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases: the evolution from myeloablative to lymphoablative transplant regimens
    Richard K Burt
    Northwestern University Feinberg School of Medicine, Chicago, Illinois 60011, USA
    Arthritis Rheum 54:3750-60. 2006
  28. doi Allogeneic transplantation improves the overall and progression-free survival of Hodgkin lymphoma patients relapsing after autologous transplantation: a retrospective study based on the time of HLA typing and donor availability
    Barbara Sarina
    Hematology Department, Istituto Clinico Humanitas, Milano, Italy
    Blood 115:3671-7. 2010
    Hodgkin lymphoma relapsing after autologous transplantation (autoSCT) has a dismal outcome. Allogeneic transplantation (alloSCT) using reduced intensity conditioning (RIC) is a salvage option, but its effectiveness is still unclear...
  29. doi Therapeutic angiogenesis in Buerger's disease (thromboangiitis obliterans) patients with critical limb ischemia by autologous transplantation of bone marrow mononuclear cells
    Vishnu Motukuru
    Jain Institute of Vascular Sciences, Bhagawan Mahaveer Jain Hospital, Bangalore, India
    J Vasc Surg 48:53S-60S; discussion 60S. 2008
    ..We have reviewed our series of patients who underwent autologous bone marrow mononuclear cell transplantation during the last 2 years...
  30. ncbi Autologous bone marrow-derived mononuclear cell therapy prevents the damage of viable myocardium and improves rat heart function following acute anterior myocardial infarction
    Hon Kan Yip
    Division of Cardiology, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Circ J 72:1336-45. 2008
    ..We examined the effects of bone marrow-derived mononuclear cells (BMDMNCs) on preventing viable myocardium damage from myocardial infarction (MI) in a rat MI model...
  31. ncbi A randomized trial comparing autologous chondrocyte implantation with microfracture. Findings at five years
    Gunnar Knutsen
    Department of Orthopaedic Surgery, University of Tromsø, University Hospital North Norway, 9038 Tromsø, Norway
    J Bone Joint Surg Am 89:2105-12. 2007
    ..The objective of this randomized trial was to compare autologous chondrocyte implantation with microfracture. This paper represents an update, with presentation of the clinical results at five years...
  32. ncbi Molecular remission after allogeneic or autologous transplantation of hematopoietic stem cells for multiple myeloma
    G Martinelli
    Institute of Hematology and Medical Oncology Seragnoli, University of Bologna, Italy
    J Clin Oncol 18:2273-81. 2000
    ....
  33. ncbi Early autologous stem-cell transplantation versus conventional chemotherapy as front-line therapy in high-risk, aggressive non-Hodgkin's lymphoma: an Italian multicenter randomized trial
    Maurizio Martelli
    Department of Cellular Biotechnology and Hematology, University La Sapienza of Rome, Italy
    J Clin Oncol 21:1255-62. 2003
    ..To evaluate the role of early intensification with high-dose therapy (HDT) and autologous stem-cell transplantation (ASCT) as front-line chemotherapy for patients with high-risk, histologically aggressive non-Hodgkin's lymphoma (NHL)...
  34. ncbi Single versus double autologous stem-cell transplantation for multiple myeloma
    Michel Attal
    Department of Hematology and Biostatistics, Hopital Purpan, Toulouse, France
    N Engl J Med 349:2495-502. 2003
    ..We conducted a randomized trial of the treatment of multiple myeloma with high-dose chemotherapy followed by either one or two successive autologous stem-cell transplantations...
  35. ncbi Nonmyeloablative allogeneic hematopoietic transplantation: a promising salvage therapy for patients with non-Hodgkin's lymphoma whose disease has failed a prior autologous transplantation
    Maricer P Escalon
    Department of Blood and Marrow Transplantation, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 22:2419-23. 2004
    Allogeneic transplantation for patients with lymphoma who experience a recurrence after an autologous transplantation has been considered a hazardous therapeutic choice...
  36. ncbi Autologous transplantation of muscle-derived CD133+ stem cells in Duchenne muscle patients
    Y Torrente
    Fondazione IRCCS Ospedale Maggiore Policlinico of Milan, Department of Neurological Sciences, Dino Ferrari Center, University of Milan, Italy
    Cell Transplant 16:563-77. 2007
    ..Here we tested the safety of autologous transplantation of muscle-derived CD133+ cells in eight boys with Duchenne muscular dystrophy in a 7-month, double-blind ..
  37. ncbi Prospective nonrandomized comparison of an allograft with bone morphogenic protein versus an iliac-crest autograft in anterior cervical discectomy and fusion
    Glenn Robin Buttermann
    Midwest Spine Institute Stillwater, Spine Surgery Division, 1950 Curve Crest Blvd, Stillwater, MN 55115, USA
    Spine J 8:426-35. 2008
    ..This has led some surgeons to use alternatives to iliac bone graft, but often the alternatives have greater rates of nonunion and delayed union. Bone morphogenic protein (BMP) studies have found high arthrodesis rates in lumbar fusions...
  38. ncbi Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life
    Riccardo Saccardi
    Bone Marrow Transplantation Unit, Careggi Hospital, University of Florence, Italy
    Blood 105:2601-7. 2005
    ..HSCT is able to induce a prolonged clinical stabilization in severe progressive MS patients, resulting in both sustained treatment-free periods and quality of life improvement...
  39. ncbi Osteochondral lesions of the talus: randomized controlled trial comparing chondroplasty, microfracture, and osteochondral autograft transplantation
    Alberto Gobbi
    Orthopaedic Arthroscopic Surgery International, Milan, Italy
    Arthroscopy 22:1085-92. 2006
    The purpose of this study was to compare outcomes of chondroplasty versus microfracture versus osteochondral autologous transplantation (OAT) in patients with osteochondral lesions of the talus (OLT).
  40. ncbi Arthroscopic autologous chondrocyte transplantation: technical note
    M Marcacci
    Laboratorio di Biomeccanica, Istituti Ortopedici Rizzoli, Via Di Barbiano 1 10, 40136 Bologna, Italy
    Knee Surg Sports Traumatol Arthrosc 10:154-9. 2002
    ..The procedure includes the advantages of arthroscopic osteochondral grafting without donor site morbidity. With this technique is possible to reduce the patient morbidity, time and cost of surgery...
  41. doi Long-term follow-up results of IFM99-03 and IFM99-04 trials comparing nonmyeloablative allotransplantation with autologous transplantation in high-risk de novo multiple myeloma
    Philippe Moreau
    Blood 112:3914-5. 2008
  42. ncbi CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis: report of toxicity and treatment results at one year of follow-up in 15 patients
    Enric Carreras
    BMT Unit, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Haematologica 88:306-14. 2003
    ..We report the results of a phase II trial to evaluate feasibility and toxicity of CD34+ selected ASCT (CD34+/ASCT) and treatment results at one year of follow-up...
  43. ncbi Treatment of multiple myeloma
    Bart Barlogie
    Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Blood 103:20-32. 2004
    ..Fundamental and clinical research should, therefore, focus on the molecular and biologic mechanisms of treatment failure in the high-risk subgroup...
  44. ncbi Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: definitions and current practice in Europe
    P Ljungman
    Department of Hematology, Karolinska University Hospital, Stockholm, Sweden
    Bone Marrow Transplant 37:439-49. 2006
    ..The introduction of alternative therapies has challenged well-established indications such as imatinib for chronic myeloid leukaemia. An updated report with revised tables and operating definitions is presented here...
  45. ncbi Autologous transplantation of porcine myogenic precursor cells in skeletal muscle
    Nicolas Holzer
    Department of Clinical Neurosciences and Dermatology, Geneva Faculty of Medicine and University Hospital, Geneva, Switzerland
    Neuromuscul Disord 15:237-44. 2005
    ..b>Autologous transplantation of 3[H]-thymidine labeled porcine myogenic precursor cells indicated 60% survival at day 1 followed by a ..
  46. ncbi Impact of chromosome 13 deletion and plasma cell load on long-term survival of patients with multiple myeloma undergoing autologous transplantation
    Esbjörn Paul
    Hematology Center, Karolinska University Hospital and Division of Hematology, Department of Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Oncol Rep 22:137-42. 2009
    ..020), whereas the plasma cell load had no effect on survival of patients with del(13). Overall, the absence of del(13) in combination with low plasma cell infiltration at diagnosis predicts the best survival...
  47. ncbi Peripheral blood stem cell mobilization by granulocyte colony-stimulating factor alone and engraftment kinetics following autologous transplantation in children and adolescents with solid tumor
    H Watanabe
    Department of Pediatrics, University of Tokushima Graduate School of Medical Science, Tokushima, Japan
    Bone Marrow Transplant 37:661-8. 2006
    ....
  48. doi Human islet isolation for autologous transplantation: comparison of yield and function using SERVA/Nordmark versus Roche enzymes
    T Anazawa
    Schulze Diabetes Institute, Department of Surgery, University of Minnesota, Minneapolis, MN, USA
    Am J Transplant 9:2383-91. 2009
    ..The SN and LH enzymes are associated with similar outcomes for IAT. Further optimization of the collagenase/neutral protease ratio is necessary to reduce the number of embedded islets obtained when using the SN enzyme...
  49. ncbi Occult tumor contamination of hematopoietic stem-cell products does not affect clinical outcome of autologous transplantation in patients with metastatic breast cancer
    B W Cooper
    Department of Medicine, Ireland Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA
    J Clin Oncol 16:3509-17. 1998
    ..To determine whether occult tumor contamination of autologous bone marrow or peripheral-blood progenitor cells (PBPC) influences clinical outcome after high-dose chemotherapy in patients with stage IV breast cancer...
  50. doi Plerixafor (Mozobil) alone to mobilize hematopoietic stem cells from multiple myeloma patients for autologous transplantation
    Neal Flomenberg
    Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Biol Blood Marrow Transplant 16:695-700. 2010
    ..Further research into single agent use should focus on alternate route of administration as well as adjustment of the timing of the apheresis to improve cell HSC yield...
  51. ncbi Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction
    Volker Schachinger
    Department of Internal Medicine III, Johann Wolfgang Goethe University, Frankfurt, Germany
    N Engl J Med 355:1210-21. 2006
    ..Pilot trials suggest that the intracoronary administration of autologous progenitor cells may improve left ventricular function after acute myocardial infarction...
  52. ncbi Pilot trial of autologous dendritic cells loaded with tumor lysate(s) from allogeneic tumor cell lines in patients with metastatic medullary thyroid carcinoma
    Thomas Bachleitner-Hofmann
    Department of Surgery, Medical University of Vienna, A 1090 Vienna, Austria
    Oncol Rep 21:1585-92. 2009
    ..Combined treatment with different tumor cell lysate-pulsed DCs increases the likelihood of a calcitonin tumor marker response and should therefore be preferred over monotherapy with DCs pulsed with a single lysate...
  53. ncbi Heat-shock proteins and their role in chondrocyte protection, an application for autologous transplantation
    D A Sawatzky
    Experimental Pathology Group, William Harvey Research Institute, Saint Bartholomew s and the Royal London School of Medicine and Dentistry, Queen Mary and Westfield College, Charterhouse Square, London, EC1M 6BQ, UK
    Inflammopharmacology 12:569-89. 2005
    ....
  54. ncbi Outcome of diffuse alveolar hemorrhage in hematopoietic stem cell transplant recipients
    Bekele Afessa
    Department of Medicine, Divisions of Pulmonary and Critical Care Medicine and Hematology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Respir Crit Care Med 166:1364-8. 2002
    ..This study shows that survival rate of hematopoietic stem cell transplant recipients with diffuse alveolar hemorrhage is better than previously reported, and that early onset and autologous transplant are favorable prognostic indicators...
  55. ncbi Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure
    Emerson C Perin
    Texas Heart Institute at St Luke s Episcopal Hospital, Houston, Tex, USA
    Circulation 107:2294-302. 2003
    ....
  56. ncbi Autologous transplantation of bone marrow mononuclear stem cells by mini-thoracotomy in dilated cardiomyopathy: technique and early results
    Renato Abdala Karam Kalil
    Instituto de Cardiologia do Rio Grande do Sul, Fundação Universitária de Cardiologia, Porto Alegre, Rio Grande do Sul, Brazil
    Sao Paulo Med J 126:75-81. 2008
    ..This study describes a novel technique of BMMC transplantation and the results up to one year after the procedure...
  57. ncbi Randomized comparison of granulocyte colony-stimulating factor versus granulocyte-macrophage colony-stimulating factor plus intensive chemotherapy for peripheral blood stem cell mobilization and autologous transplantation in multiple myeloma
    Mukta Arora
    Department of Medicine, University of Minnesota, Minneapolis 55455, USA
    Biol Blood Marrow Transplant 10:395-404. 2004
    ..colony-stimulating factor (GM-CSF) for peripheral blood stem cell mobilization followed by autologous transplantation. The major study end points were the comparative utility of G-CSF versus GM-CSF, the percentage of ..
  58. doi Autologous transplantation of RPE with partial-thickness choroid after mechanical debridement of Bruch membrane in the rabbit
    Yuntao Hu
    Peking University Eye Center, Peking University Third Hospital, Beijing, China
    Invest Ophthalmol Vis Sci 49:3185-92. 2008
    ..An improved translocation technique for autologous retinal pigment epithelium (RPE) transplantation is presented. The graft consists of a sheet of a partial-thickness choroid with RPE attached...
  59. ncbi Cryopreservation of human brain tissue allowing timely production of viable adult human brain cells for autologous transplantation
    Jean Francois Brunet
    Department of Neurosurgery of Lausanne and Geneva University Medical School, Bugnon 46, 1011, Lausanne, Switzerland
    Cryobiology 47:179-83. 2003
    b>Autologous transplantation is an attractive approach to treat some neurological diseases. A major obstacle is the capacity to produce cells for transplantation at the appropriate time...
  60. doi Photoreceptors repair by autologous transplantation of retinal pigment epithelium and partial-thickness choroid graft in rabbits
    Taoran Zhang
    Peking University Eye Center, Peking University Third Hospital, Beijing, China
    Invest Ophthalmol Vis Sci 50:2982-8. 2009
    ..To investigate whether autologous retinal pigment epithelium (RPE) and a partial-thickness graft can repair degenerated photoreceptors overlying a mechanically damaged Bruch's membrane...
  61. doi Intensive induction chemotherapy followed by high dose chemotherapy with autologous hematopoietic progenitor cell rescue in young children newly diagnosed with central nervous system atypical teratoid rhabdoid tumors
    Sharon L Gardner
    Department of Pediatrics, New York University, New York, New York 10016, USA
    Pediatr Blood Cancer 51:235-40. 2008
    ..Historically, surgery and standard dose chemotherapy have resulted in a median survival of 8.5 months from diagnosis...
  62. ncbi Long-term outcome of autologous transplantation of peripheral blood progenitor cells as postremission management of patients > or =60 years with acute myelogenous leukemia
    Ashkan Lashkari
    Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Biol Blood Marrow Transplant 12:466-71. 2006
    ..To better understand the long-term outcome of autologous transplantation in AML patients > or =60 years of age, we evaluated high-dose chemoradiotherapy preparative conditioning ..
  63. ncbi Syngeneic hematopoietic stem-cell transplantation for non-Hodgkin's lymphoma: a comparison with allogeneic and autologous transplantation--The Lymphoma Working Committee of the International Bone Marrow Transplant Registry and the European Group for Blood
    Philip J Bierman
    University of Nebraska Medical Center, Omaha, NE 68198 7680, USA
    J Clin Oncol 21:3744-53. 2003
    ..To compare results of syngeneic, allogeneic, and autologous hematopoietic stem-cell transplantation for non-Hodgkin's lymphoma (NHL)...
  64. pmc A comparison of HLA-identical sibling allogeneic versus autologous transplantation for diffuse large B cell lymphoma: a report from the CIBMTR
    Hillard M Lazarus
    Department of Medicine, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA
    Biol Blood Marrow Transplant 16:35-45. 2010
    ....
  65. pmc Reconstruction of damaged cornea by autologous transplantation of epidermal adult stem cells
    Xueyi Yang
    Department of Life Sciences, Luoyang Normal University, Luoyang, China
    Mol Vis 14:1064-70. 2008
    ..Here, we report a new strategy for reconstructing the damaged corneal surface in a goat model of total limbal stem cell deficiency (LSCD) by autologous transplantation of epidermal adult stem cells (EpiASC).
  66. ncbi Shortened first-line high-dose chemotherapy for patients with poor-prognosis aggressive lymphoma
    Christian Gisselbrecht
    Institut d Hematologie, GELA Hôpital Saint Louis, 1 avenue Claude Vellefaux, 75475 Paris Cedex 10, France
    J Clin Oncol 20:2472-9. 2002
    ....
  67. ncbi Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarction
    Yao Liang Tang
    Department of Physiology and Biophysics, College of Medicine, University of South Florida, St Petersburg, Florida, USA
    Ann Thorac Surg 80:229-36; discussion 236-7. 2005
    ..We hypothesize that transplantation of MSCs enhances vascular regeneration through a paracrine action...
  68. ncbi Prolonged remission of neuro-Behcet disease following autologous transplantation
    A De Cata
    Department of Internal Medicine, IRCCS, Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy
    Int J Immunopathol Pharmacol 20:91-6. 2007
    ..Immune ablation followed by APBSCT can modify the course of severe N-BD. Because of the high risk and the transplant-related mortality, these cases have to be carefully selected...
  69. ncbi Progressive disease following autologous transplantation in patients with chemosensitive relapsed or primary refractory Hodgkin's disease or aggressive non-Hodgkin's lymphoma
    T Kewalramani
    Department of Medicine, Lymphoma and Hematology Services, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Bone Marrow Transplant 32:673-9. 2003
    ....
  70. pmc Controversies in the treatment of lymphoma with autologous transplantation
    Alison J Moskowitz
    Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Oncologist 14:921-9. 2009
    ....
  71. ncbi BEAM allogeneic transplantation for patients with Hodgkin's disease who relapse after autologous transplantation is safe and effective
    Julian P Cooney
    BMT Program, Loyola University Medical Center, Maywood, Illinois, USA
    Biol Blood Marrow Transplant 9:177-82. 2003
    Because few patients failing autologous transplantation for Hodgkin's disease survive long-term, we explored reduced-intensity allografts using BEAM conditioning and early withdrawal of immunosuppression as an alternative to palliative ..
  72. ncbi Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector
    Naoki Yokoo
    Department of Orthopaedic Surgery, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama 236 0004, Japan
    Arthritis Rheum 52:164-70. 2005
    ..To examine the effects of basic fibroblast growth factor (bFGF) gene-transduced chondrocytes on the repair of articular cartilage defects...
  73. doi Complete remission status before autologous stem cell transplantation is an important prognostic factor in patients with multiple myeloma undergoing upfront single autologous transplantation
    Jin Seok Kim
    Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
    Biol Blood Marrow Transplant 15:463-70. 2009
    ..Our findings suggest that the development of more effective induction regimens, including novel antimyeloma agents to improve initial response, should be pursued to enhance clinical benefits post-ASCT...
  74. ncbi Tandem high-dose chemotherapy followed by autologous transplantation in patients with locally advanced or metastatic sarcoma
    Ashkan Lashkari
    City of Hope Comprehensive Cancer Center, Division of Medical Oncology, 1500 E Duarte Road, Duarte, CA 91010, USA
    Anticancer Res 29:3281-8. 2009
    ..The purpose of our phase II study was to assess the feasibility, safety and efficacy of tandem high-dose chemotherapy (HDCT) followed by autologous stem cell transplantation (ASCT) in such patients...
  75. pmc Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells
    Yoo Jin Kim
    Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health NIH, Bethesda, MD 20852, USA
    Blood 113:5434-43. 2009
    ....
  76. ncbi Artificial niches for human adult neural stem cells: possibility for autologous transplantation therapy
    Charles Y Liu
    Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, 90033, USA
    J Hematother Stem Cell Res 12:689-99. 2003
    ..the clinical perspective and summarizes ongoing work aimed at exploring the intriguing possibility of autologous transplantation, whereby neural stem cells can be harvested from adult patients, expanded or modified in vitro in ..
  77. ncbi Efficacy of autologous transplantation of noncultured epidermal suspension in two different dilutions in the treatment of vitiligo
    Geeta R Tegta
    Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Int J Dermatol 45:106-10. 2006
    ....
  78. ncbi Quality of life assessment in patients undergoing reduced intensity conditioning allogeneic as compared to autologous transplantation: results of a prospective study
    M Diez-Campelo
    Servicio de Hematologia, Hospital Universitario de Salamanca, Paseo de San Vicente, S N, 37007 Salamanca, Spain
    Bone Marrow Transplant 34:729-38. 2004
    ..We have observed similar QOL among patients undergoing RIC-allo as compared to ASCT although GVHD remains an important 'event' in QOL...
  79. ncbi Therapeutic neovascularization by autologous transplantation with expanded endothelial progenitor cells from peripheral blood into ischemic hind limbs
    Chun ling Fan
    Shanghai Key Laboratory of Vascular Biology, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China
    Acta Pharmacol Sin 26:1069-75. 2005
    ..To investigate the hypothesis that transplantation with expanded autologous endothelial progenitor cells (EPC) could enhance neovascularization...
  80. ncbi Negative selection of peripheral blood stem cells to support a tandem autologous transplantation programme in multiple myeloma
    Anna Maria Barbui
    Divisione di Ematologia, Radioterapia and Centro Trasfusionale, Ospedali Riuniti, Bergamo, Italy
    Br J Haematol 116:202-10. 2002
    ..05), whereas the estimated overall survival was 83% in both arms. This suggests that autologous transplantation using efficiently purged PBSCs can be performed safely, but confirms the need for innovative protocols ..
  81. ncbi The morbidity associated with osteochondral harvest from asymptomatic knees for the treatment of osteochondral lesions of the talus
    Sudheer Reddy
    Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Sports Med 35:80-5. 2007
    ..Mosaic autogenous osteochondral transplantation has been used to treat large osteochondral defects...
  82. ncbi Direct intramyocardial percutaneous delivery of autologous bone marrow in patients with refractory myocardial angina
    Carlo Briguori
    Vita Salute University School of Medicine, San Raffaele Hospital, Milan, Italy
    Am Heart J 151:674-80. 2006
    ..Intramyocardial injection of autologous bone marrow (ABM) may induce angiogenesis. We tested the safety and feasibility of catheter-based direct percutaneous intramyocardial delivery of ABM in patients with refractory angina pectoris...
  83. ncbi Impact of different strategies of second-line stem cell harvest on the outcome of autologous transplantation in poor peripheral blood stem cell mobilizers
    R Goterris
    Hematology and Medical Oncology Service, Hospital Clinico Universitario, University of Valencia, Valencia, Spain
    Bone Marrow Transplant 36:847-53. 2005
    ..PBSC harvest yielded significantly more CD34+ cells than BM collection. Autologous transplantation was performed in 30, 23 and 11 patients from groups A, B and C, respectively...
  84. ncbi Prognostic importance of the axillary lymph node ratio in autologous transplantation for high-risk stage II/III breast cancer
    B Bolwell
    Department of Hematology and Medical Oncology, and Transplant Center, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Bone Marrow Transplant 27:843-6. 2001
    ..0001 and P = 0.004, respectively). We conclude that patients having a node ratio of < 0.7 have a significantly better prognosis following autologous PBPC transplantation than do patients with a ratio > or = 0.7...
  85. ncbi Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial
    Amar Gajjar
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Lancet Oncol 7:813-20. 2006
    ..We aimed to investigate the effectiveness of risk-adapted radiotherapy followed by a shortened period of dose-intense chemotherapy in children with medulloblastoma...
  86. ncbi Infections after CD34-selected or unmanipulated autologous hematopoietic stem cell transplantation
    Pascale Frère
    Division of Hematology, Department of Medicine, University of Liege, Liege, Belgium
    Eur J Haematol 76:102-8. 2006
    ..The role of extended infection prophylaxis should be evaluated...
  87. ncbi Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network
    Isme de Kleer
    University Medical Center Utrecht, Wilhelmina Children s Hospital, Home Mailbox KC 03 063 0, Department of Pediatric Immunology, PO Box 85090, 3508 AB Utrecht, The Netherlands
    Blood 107:1696-702. 2006
    ....
  88. ncbi Autologous cartilage implantation for full thickness articular cartilage defects of the knee
    J Wasiak
    Alfred Hospital, Victorian Adult Burns Service, Commercial Road, Prahran, Melbourne, Victoria, Australia 3004
    Cochrane Database Syst Rev 3:CD003323. 2006
    ..An alternative is the surgical implantation of healthy cartilage cells into damaged areas (autologous cartilage implantation)...
  89. ncbi Early lymphocyte recovery predicts longer survival after autologous peripheral blood stem cell transplantation in multiple myeloma
    H Kim
    Division of Hematology Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea
    Bone Marrow Transplant 37:1037-42. 2006
    ..031) and prolonged PFS (P=0.011), and that serum beta2-microglobulin was marginally significant for prolonged OS (P=0.066). In conclusion, ALC recovery was an independent predictor of both OS and PFS in MM...
  90. ncbi Orthotopic transplantation of fresh ovarian cortex: a report of two cases
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires Saint Luc, Brussels, Belgium
    Fertil Steril 84:1018. 2005
    ..To report two cases of orthotopic transplantation of fresh ovarian tissue...
  91. ncbi Percutaneous intracoronary cellular cardiomyoplasty for nonischemic cardiomyopathy: clinical and histopathological results: the first-in-man ABCD (Autologous Bone Marrow Cells in Dilated Cardiomyopathy) trial
    Sandeep Seth
    J Am Coll Cardiol 48:2350-1. 2006
  92. ncbi The results of consolidation with autologous stem-cell transplantation in patients with peripheral T-cell lymphoma (PTCL) in first complete remission: the Spanish Lymphoma and Autologous Transplantation Group experience
    J Rodriguez
    Service of Oncology, Hospital Universitario Son Dureta, Av Andrea Doria 55, Palma de Mallorca 07014, Spain
    Ann Oncol 18:652-7. 2007
    ..Consolidation with autologous stem-cell transplantation (ASCT) may improve survival. We present 74 patients transplanted in first complete response (CR) from the Spanish Lymphoma and Autologous Transplantation Group cooperative group.
  93. ncbi High-dose therapy with single autologous transplantation versus chemotherapy for newly diagnosed multiple myeloma: A systematic review and meta-analysis of randomized controlled trials
    John Koreth
    Division of Hematologic Malignancies, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Biol Blood Marrow Transplant 13:183-96. 2007
    ..96). The totality of the randomized data indicates PFS benefit but not OS benefit for HDT with single autologous transplantation performed early in multiple myeloma...
  94. pmc Membrane-seeded autologous chondrocytes: cell viability and characterization at surgery
    Antonio Gigante
    Department of Orthopaedics, Polytechnic University of Marche, Via Tronto 10, 60020 Ancona, Italy
    Knee Surg Sports Traumatol Arthrosc 15:88-92. 2007
    ..These data reassure in that the MACI procedure provides a suitable engineered tissue for cartilage repair, in line with the clinical evidences emerging in the literature...
  95. ncbi Early lymphocyte recovery following autologous peripheral stem cell transplantation is associated with better survival in younger patients with lymphoproliferative disorders
    M R Boulassel
    Division of Hematology, McGill University Health Centre, Royal Victoria Hospital, Montreal, Que, H3A 1A1 Canada
    Hematology 11:165-70. 2006
    ..A shorter time from diagnosis to APSCT may favor recovery of ALC independent of the infused stem cell or lymphocyte doses...
  96. ncbi Autologous transplantation of the retinal pigment epithelium and choroid in the treatment of neovascular age-related macular degeneration
    Robert E MacLaren
    Moorfields Eye Hospital, City Road, London, UK
    Ophthalmology 114:561-70. 2007
    To assess excision of choroidal new vessels (CNV) combined with autologous transplantation of the equatorial retinal pigment epithelium (RPE) as a means of restoring vision for patients with acute neovascular age-related macular ..
  97. ncbi Early lymphocyte recovery after autologous stem cell transplantation predicts superior survival in mantle-cell lymphoma
    C Joao
    Hematology Department, Portuguese Institute of Oncology, Lisbon, Portugal
    Bone Marrow Transplant 37:865-71. 2006
    ..0006, respectively). Multivariate analysis demonstrated ALC-15 to be an independent prognostic factor for OS and PFS. The ALC-15 >or=500 cells/microl is associated with a significantly improved clinical outcome following ASCT in MCL...
  98. ncbi Apheresis instrument settings influence infused absolute lymphocyte count affecting survival following autologous peripheral hematopoietic stem cell transplantation in non-Hodgkin's lymphoma: the need to optimize instrument setting and define a lymphocyte
    R Katipamula
    Division of Transfusion Medicine, Mayo Clinic, Rochester, MN 55902, USA
    Bone Marrow Transplant 37:811-7. 2006
    ..These data suggest that apheresis instrument settings should be optimized to collect CD34(+) cells as well as an A-ALC target, with direct impact on survival post-APHSCT...
  99. ncbi Fat grafting to the breast revisited: safety and efficacy
    Sydney R Coleman
    New York University School of Medicine, New York, NY 10013, USA
    Plast Reconstr Surg 119:775-85; discussion 786-7. 2007
    ..As discussions of fat grafting to the breast are surfacing all over the world, it is time to reexamine the opinions of the 1987 American Society of Plastic and Reconstructive Surgeons position paper...
  100. ncbi Maintenance therapy with thalidomide improves overall survival after autologous hematopoietic progenitor cell transplantation for multiple myeloma
    Brett T Brinker
    Division of Hematology and Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer 106:2171-80. 2006
    ..The objective of this retrospective review of autologous HPC transplantation for patients with MM was to evaluate the impact of conditioning regimens and posttransplantation therapy on survival...
  101. ncbi Harvesting and autotransplantation of vascularized ovarian grafts: approaches and techniques
    Mohamed A Bedaiwy
    Minimally Invasive Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Reprod Biomed Online 14:360-71. 2007
    ..The inferior epigastric vessel is probably the most suitable heterotopic vascularizing vessel. End-to-end anastomosis yields the highest patency rate of vascularized grafts...

Research Grants76

  1. Stem cell-mediated delivery of neurotrophic factors for treatment of glaucoma
    Donald S Sakaguchi; Fiscal Year: 2010
    ..First, MSCs can be easily isolated, cultured, and propagated as a source of adult stem cells for autologous transplantation, inciting minimal host immune response...
  2. GENE THERAPY FOR INHERITED JAUNDICE
    Jayanta Roy Chowdhury; Fiscal Year: 1993
    ..Because the method involves autologous transplantation, immune rejection is not a problem and immunosuppression will not be needed...
  3. ICE-FREE PRESERVATION OF OVARIES FOR LONG-TERM FECUNDITY
    Ying Song; Fiscal Year: 2004
    ..Cryopreservation of ovarian tissue prior to initiation of cancer therapy, followed by autologous transplantation or in vitro maturation and in vitro fertilization after remission, could provide a means of protecting ..
  4. PROLIFERATIVE CAPACITY AND RADIOBIOLOGY OF STEM CELLS
    Peter Mauch; Fiscal Year: 1999
    ..For autologous transplantation, especially when transplantation is being proposed for correction of genetic disorders, there may be an ..
  5. Anti-TfR IgG3-Av: A New Drug Against Multiple Myeloma
    MANUEL PENICHET; Fiscal Year: 2007
    ..efficient purging of myeloma cells during ex vivo expansion of hematopoietic progenitor-cells for use in autologous transplantation in MM patients...
  6. Anti-TfR IgG3-Av: A New Drug Against Multiple Myeloma
    MANUEL PENICHET; Fiscal Year: 2007
    ..efficient purging of myeloma cells during ex vivo expansion of hematopoietic progenitor-cells for use in autologous transplantation in MM patients...
  7. Anti-TfR IgG3-Av: A New Drug Against Multiple Myeloma
    MANUEL PENICHET; Fiscal Year: 2009
    ..efficient purging of myeloma cells during ex vivo expansion of hematopoietic progenitor-cells for use in autologous transplantation in MM patients...
  8. IMPROVED CONDITIONS FOR HUMAN HEMATOPOIETIC CELL CULTURE
    ELEFTHERIOS PAPOUTSAKIS; Fiscal Year: 1993
    ..system to amplify hematopoietic progenitor cells could increase the number of patients eligible for autologous transplantation, allow use of cord blood hematopoietic cells to repopulate an adult, reduce the amount of bone marrow ..
  9. PO2 AND PH AS POTENT MODULATORS OF HEMATOPOIESIS
    ELEFTHERIOS PAPOUTSAKIS; Fiscal Year: 2002
    ..system to amplify hematopoietic progenitor cells could increase the number of patients eligible for autologous transplantation, allow use of cord blood hematopoietic cells to repopulate an adult, reduce the amount of bone marrow ..
  10. Keratin Gene Targeting for the Treatment of Epidermolysis Bullosa
    Daniel G Miller; Fiscal Year: 2010
    ..We propose to correct the phenotype of EBS-patient keratinocytes and prepare them for autologous transplantation by using a gene targeting approach...
  11. AAV-mediated gene therapy for metabolic bone disease
    Selvarangan Ponnazhagan; Fiscal Year: 2009
    ..Thus, we hypothesize that autologous transplantation of culture-expanded MSC, transduced with rAAV encoding BMP-2 under the control of osteoprogenitor-..
  12. Symposium- Advances in Stem Cell Transplantation
    Edward Ball; Fiscal Year: 2003
    ..myeloablative transplants may permit innovative approaches to stem cell transplantation including tandem autologous transplantation to achieve cytoreduction followed by non-myeloablative allogeneic transplants to achieve the ..
  13. MOLECULAR STUDY OF MPSI-GENE THERAPY IN CANINE MODEL
    ELIZABETH NEUFELD; Fiscal Year: 1993
    ..The effects of autologous transplantation of genetically modified bone marrow on the course of the disease will be compared to the previously ..
  14. Bone Marrow Stem Cells: Novel Treatment of Human Glioma
    Frederick Lang; Fiscal Year: 2007
    ..Additionally, to better mimic autologous transplantation, the capacity of mMSCs to survive within and outside gliomas will be explored in syngeneic, ..
  15. Bone Marrow Stem Cells: Novel Treatment of Human Glioma
    Frederick F Lang; Fiscal Year: 2010
    ..Additionally, to better mimic autologous transplantation, the capacity of mMSCs to survive within and outside gliomas will be explored in syngeneic, ..
  16. Bone Marrow Stem Cells: Novel Treatment of Human Glioma
    Frederick Lang; Fiscal Year: 2009
    ..Additionally, to better mimic autologous transplantation, the capacity of mMSCs to survive within and outside gliomas will be explored in syngeneic, ..
  17. MOLECULAR PATHOGENESIS/TREATMENT OF HYPOPHOSPHATASIA
    Jose Luis Millan; Fiscal Year: 2003
    ..results from mutations affecting different functional domains in the TNAP molecule and B) that autologous transplantation of ex vivo manipulated bone marrow osteoprogenitor stem cells may be a viable treatment modality for ..
  18. OSTEOGENIC MECHANISMS OF SHED
    Songtao Shi; Fiscal Year: 2009
    ..Finally, we develop optimal conditions to expand minipig SHED and utilize them for autologous transplantation to repair parietal defects, which is a necessary pre-clinical step to examine any efficacy and potential ..
  19. OSTEOGENIC MECHANISMS OF SHED
    Songtao Shi; Fiscal Year: 2010
    ..Finally, we develop optimal conditions to expand minipig SHED and utilize them for autologous transplantation to repair parietal defects, which is a necessary pre-clinical step to examine any efficacy and potential ..