mastectomy

Summary

Top Publications

  1. ncbi Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
    Edward H Romond
    National Surgical Adjuvant Breast and Bowel Project, Pittsburgh, USA
    N Engl J Med 353:1673-84. 2005
  2. ncbi Ductal carcinoma in situ of the breast
    Harold J Burstein
    Division of Medical Oncology and the Department of Medicine, Dana Farber Cancer Institute, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 350:1430-41. 2004
  3. pmc Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile
    K Graham
    Boston University School of Medicine and Boston Medical Center, MA, USA
    Br J Cancer 102:1284-93. 2010
  4. ncbi Granulomatous lobular mastitis: a complex diagnostic and therapeutic problem
    Alper Akcan
    Department of General Surgery, Erciyes University Medical Faculty, Kayseri, Turkey
    World J Surg 30:1403-9. 2006
  5. ncbi Lung carcinoma after radiation therapy in women treated with lumpectomy or mastectomy for primary breast carcinoma
    Lydia B Zablotska
    Department of Epidemiology, Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Cancer 97:1404-11. 2003
  6. pmc Lymphedema and quality of life in breast cancer survivors: the Iowa Women's Health Study
    Rehana L Ahmed
    Department of Dermatology, University of Minnesota, Minneapolis, MN 55455 0392, USA
    J Clin Oncol 26:5689-96. 2008
  7. ncbi Eighteen-year results in the treatment of early breast carcinoma with mastectomy versus breast conservation therapy: the National Cancer Institute Randomized Trial
    Matthew M Poggi
    Radiation Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA
    Cancer 98:697-702. 2003
  8. ncbi The oncological safety of skin sparing mastectomy with conservation of the nipple-areola complex and autologous reconstruction: an extended follow-up study
    Bernd Gerber
    Department of Obstetrics and Gynecology, University of Rostock, Rostock, Germany
    Ann Surg 249:461-8. 2009
  9. ncbi Randomized clinical trial investigating the use of drains and fibrin sealant following surgery for breast cancer
    P K Jain
    Department of Surgery, Scarborough General Hospital, Woodland Drive, Scarborough YO12 6QL, UK
    Br J Surg 91:54-60. 2004
  10. ncbi Breast conserving therapy versus mastectomy for stage I-II breast cancer: 20 year follow-up of the EORTC 10801 phase 3 randomised trial
    Saskia Litière
    European Organisation for Research and Treatment of Cancer, Brussels, Belgium
    Lancet Oncol 13:412-9. 2012

Research Grants

  1. Cellular Mechanisms of Lymphatic Muscle Contractility
    Michael Davis; Fiscal Year: 2009
  2. Cellular Mechanisms of Lymphatic Muscle Contractility
    MICHAEL JOHN DAVIS; Fiscal Year: 2010
  3. A new class of biodegradable synthetic biomaterial for seroma prevention
    Michael Craven; Fiscal Year: 2012
  4. VARIABLES AFFECTING OSTOMY PATIENT OUTCOME
    Debra Jackson; Fiscal Year: 1991
  5. Managed Care Penetration and Cancer Care
    Edward Guadagnoli; Fiscal Year: 2002
  6. Managed Care Penetration and Cancer Care
    Edward Guadagnoli; Fiscal Year: 2001
  7. Managed Care Penetration and Cancer Care
    Nancy Keating; Fiscal Year: 2003
  8. Presurgery Hypnosis--Benefits Analysis in Breast Cancer
    Guy Montgomery; Fiscal Year: 2002
  9. Presurgery Hypnosis--Benefits Analysis in Breast Cancer
    Guy Montgomery; Fiscal Year: 2001
  10. TRAUMATIC PAINFUL NEUROPATHY AND CALCIUM SIGNALING
    Quinn Hogan; Fiscal Year: 2002

Detail Information

Publications301 found, 100 shown here

  1. ncbi Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
    Edward H Romond
    National Surgical Adjuvant Breast and Bowel Project, Pittsburgh, USA
    N Engl J Med 353:1673-84. 2005
    ..We present the combined results of two trials that compared adjuvant chemotherapy with or without concurrent trastuzumab in women with surgically removed HER2-positive breast cancer...
  2. ncbi Ductal carcinoma in situ of the breast
    Harold J Burstein
    Division of Medical Oncology and the Department of Medicine, Dana Farber Cancer Institute, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 350:1430-41. 2004
  3. pmc Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile
    K Graham
    Boston University School of Medicine and Boston Medical Center, MA, USA
    Br J Cancer 102:1284-93. 2010
    ..between breast cancer patients and usual-risk controls undergoing reduction mammoplasty (RM), and that gene expression in NlEpi from cancer-free prophylactic mastectomy (PM) samples from high-risk women would resemble HN gene expression.
  4. ncbi Granulomatous lobular mastitis: a complex diagnostic and therapeutic problem
    Alper Akcan
    Department of General Surgery, Erciyes University Medical Faculty, Kayseri, Turkey
    World J Surg 30:1403-9. 2006
    ..The purpose of this study is to evaluate diagnostic difficulties and discuss the outcome of surgical treatment in a series of 21 patients with granulomatous lobular mastitis...
  5. ncbi Lung carcinoma after radiation therapy in women treated with lumpectomy or mastectomy for primary breast carcinoma
    Lydia B Zablotska
    Department of Epidemiology, Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Cancer 97:1404-11. 2003
    Prior studies have demonstrated that women who receive adjuvant radiation therapy (RT) after mastectomy for breast carcinoma have an increased risk of a second primary lung carcinoma after 10 years, but, to the authors' knowledge, the ..
  6. pmc Lymphedema and quality of life in breast cancer survivors: the Iowa Women's Health Study
    Rehana L Ahmed
    Department of Dermatology, University of Minnesota, Minneapolis, MN 55455 0392, USA
    J Clin Oncol 26:5689-96. 2008
    ..The impact of lymphedema or related arm symptoms on health-related quality of life (HRQOL) in breast cancer (BrCa) survivors has not been examined using a large population-based cohort...
  7. ncbi Eighteen-year results in the treatment of early breast carcinoma with mastectomy versus breast conservation therapy: the National Cancer Institute Randomized Trial
    Matthew M Poggi
    Radiation Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA
    Cancer 98:697-702. 2003
    Between 1979-1987, the National Cancer Institute conducted a randomized, prospective study of mastectomy (MT) versus breast conservation therapy (BCT) in the treatment of patients with early-stage breast carcinoma...
  8. ncbi The oncological safety of skin sparing mastectomy with conservation of the nipple-areola complex and autologous reconstruction: an extended follow-up study
    Bernd Gerber
    Department of Obstetrics and Gynecology, University of Rostock, Rostock, Germany
    Ann Surg 249:461-8. 2009
    To find out if skin sparing mastectomy (SSM) and nipple sparing mastectomy (NSM) with immediate autologous reconstruction as safe in oncological terms as modified radical mastectomy (MRM).
  9. ncbi Randomized clinical trial investigating the use of drains and fibrin sealant following surgery for breast cancer
    P K Jain
    Department of Surgery, Scarborough General Hospital, Woodland Drive, Scarborough YO12 6QL, UK
    Br J Surg 91:54-60. 2004
    ..The aim of this study was to evaluate the effect of drains and fibrin sealant on the incidence of seroma formation...
  10. ncbi Breast conserving therapy versus mastectomy for stage I-II breast cancer: 20 year follow-up of the EORTC 10801 phase 3 randomised trial
    Saskia Litière
    European Organisation for Research and Treatment of Cancer, Brussels, Belgium
    Lancet Oncol 13:412-9. 2012
    The EORTC 10801 trial compared breast-conserving therapy (BCT) with modified radical mastectomy (MRM) in patients with tumours 5 cm or smaller and axillary node negative or positive disease...
  11. ncbi Differences in risk factors for local and distant recurrence after breast-conserving therapy or mastectomy for stage I and II breast cancer: pooled results of two large European randomized trials
    A C Voogd
    Eindhoven Cancer Registry, The Netherlands Cancer Institute, Eindhoven, The Netherlands
    J Clin Oncol 19:1688-97. 2001
    Risk factors for local and distant recurrence after breast-conserving therapy and mastectomy were compared to define guidelines for the decision making between both treatments.
  12. ncbi Skin-sparing mastectomy and immediate reconstruction is an acceptable treatment option for patients with high-risk breast carcinoma
    Kevin J Downes
    Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Cancer 103:906-13. 2005
    Skin-sparing mastectomy (SSM) followed by immediate reconstruction is an effective treatment option for patients with early-stage breast carcinoma, but its use in patients with more advanced disease is controversial.
  13. ncbi Post mastectomy adjuvant radiotherapy in breast cancer: a comparision of three hypofractionated protocols
    Abubaker Shahid
    Institute of Nuclear Medicine and Oncology INMOL, Wahdat Road, Lahore, Pakistan
    J Pak Med Assoc 59:282-7. 2009
    ..To compare three hypofractionated protocols in postmastectomy cancinoma breast in terms of local control, toxicity and work load...
  14. ncbi Quality of life at the end of primary treatment of breast cancer: first results from the moving beyond cancer randomized trial
    Patricia A Ganz
    School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
    J Natl Cancer Inst 96:376-87. 2004
    ..We investigated the baseline psychosocial status of women enrolled in a randomized trial testing two psychosocial interventions for women at the end of primary treatment...
  15. ncbi Recurrence after mastectomy for ductal carcinoma in situ
    Laura N Godat
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 75:592-5; discussion 595-7. 2009
    b>Mastectomy has long been a standard option for patients with ductal carcinoma in situ (DCIS). It is preferentially chosen by some women and may be suggested for individuals with recurrent, multifocal, or multicentric disease...
  16. ncbi Randomized multicenter trial of sentinel node biopsy versus standard axillary treatment in operable breast cancer: the ALMANAC Trial
    Robert E Mansel
    Department of Surgery, Cardiff University, Cardiff, UK
    J Natl Cancer Inst 98:599-609. 2006
    ....
  17. ncbi Postmastectomy radiotherapy: clinical practice guidelines of the American Society of Clinical Oncology
    A Recht
    Beth Israel Deaconess Medical Center, Boston, MA, USA
    J Clin Oncol 19:1539-69. 2001
    ..VALIDATION: Seven outside reviewers, the American Society of Clinical Oncology (ASCO) Health Services Research Committee members, and the ASCO Board of Directors reviewed this document...
  18. ncbi Is the benefit of postmastectomy irradiation limited to patients with four or more positive nodes, as recommended in international consensus reports? A subgroup analysis of the DBCG 82 b&c randomized trials
    Marie Overgaard
    Department of Oncology, Aarhus University Hospital, Denmark
    Radiother Oncol 82:247-53. 2007
    ..A subgroup analysis of the DBCG 82 b&c trials was performed to evaluate the loco-regional recurrence rate and survival in relation to number of positive nodes...
  19. ncbi Complications in postmastectomy breast reconstruction: two-year results of the Michigan Breast Reconstruction Outcome Study
    Amy K Alderman
    Robert Wood Johnson Clinical Scholars Program, The University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0340, USA
    Plast Reconstr Surg 109:2265-74. 2002
    In this study, the effects of procedure type, timing, and other clinical variables on complication rates in mastectomy reconstruction were prospectively evaluated...
  20. doi Estrogen receptor, progesterone receptor, HER-2, and response to postmastectomy radiotherapy in high-risk breast cancer: the Danish Breast Cancer Cooperative Group
    Marianne Kyndi
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Arhus Sygehus, Noerrebrogade 44, Building 5, 2, DK 8000 Aarhus C, Denmark
    J Clin Oncol 26:1419-26. 2008
    ....
  21. ncbi Concurrent validity of upper-extremity volume estimates: comparison of calculated volume derived from girth measurements and water displacement volume
    Joy R Karges
    Department of Physical Therapy, Division of Health Sciences, School of Medicine, University of South Dakota, 414 E Clark St, Vermillion 57069, USA
    Phys Ther 83:134-45. 2003
    ..The purpose of this study was to determine the concurrent validity of calculated volume and water displacement volume measurements...
  22. ncbi Boost radiotherapy in young women with ductal carcinoma in situ: a multicentre, retrospective study of the Rare Cancer Network
    Aurelius Omlin
    Department of Radiation Oncology, University of Bern, Inselspital, Bern, Switzerland
    Lancet Oncol 7:652-6. 2006
    ..Outcome data in young women with ductal carcinoma in situ (DCIS) are rare. The benefits of boost radiotherapy in this group are also unknown. We aimed to assess the effect of boost radiotherapy in young patients with DCIS...
  23. ncbi Locoregional failure 10 years after mastectomy and adjuvant chemotherapy with or without tamoxifen without irradiation: experience of the Eastern Cooperative Oncology Group
    A Recht
    Joint Center for Radiation Therapy, Harvard Medical School, and Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Clin Oncol 17:1689-700. 1999
    ..failure and how selected prognostic and treatment factors affect the risks of locoregional failure (LRF) after mastectomy in breast cancer patients with histologically involved axillary nodes treated with chemotherapy with or without ..
  24. pmc Factors associated with local recurrence after skin-sparing mastectomy and immediate breast reconstruction for invasive breast cancer
    Heriberto Medina-Franco
    Department of Surgery, Section of Surgical Oncology, University of Alabama at Birmingham, USA
    Ann Surg 235:814-9. 2002
    To examine the incidence of local recurrence (LR) and factors associated with it in a population of patients who underwent skin-sparing mastectomy (SSM) and immediate reconstruction for invasive carcinoma.
  25. ncbi Patient involvement in surgery treatment decisions for breast cancer
    Steven J Katz
    Division of General Medicine, Department of Internal Medicine, University of Michigan, 300 N Ingalls, Ste 7E12, Box 0429, Ann Arbor, MI 48109 0429, USA
    J Clin Oncol 23:5526-33. 2005
    High rates of mastectomy and marked regional variations have motivated lingering concerns about overtreatment and failure to involve women in treatment decisions...
  26. doi Prophylactic mastectomy in high risk patients: a practice-based review of the indications. Do we follow guidelines?
    Derrick J Hoover
    Department of Surgery, Saint Barnabas Medical Center, Livingston, NJ 07039, USA
    Breast Dis 31:19-27. 2010
    ..The present study analyzed the indications and possible decision-making process leading to PM among 579 patients who underwent mastectomy.
  27. doi The increasing use of prophylactic mastectomy in the prevention of breast cancer
    Todd M Tuttle
    Department of Surgery, Division of Surgical Oncology, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55424, USA
    Curr Oncol Rep 12:16-21. 2010
    Selected high-risk women without breast cancer choose to undergo bilateral prophylactic mastectomy (BPM) to reduce their risk of developing the disease...
  28. doi Contralateral prophylactic mastectomy for unilateral breast cancer: an increasing trend at a single institution
    Natalie B Jones
    Department of Surgery, Division of Surgical Oncology, The Ohio State University, Columbus, OH, USA
    Ann Surg Oncol 16:2691-6. 2009
    An increasing trend in the use of contralateral prophylactic mastectomy (CPM) for the treatment of unilateral breast cancer has been observed nationally...
  29. doi Preoperative fluid and electrolyte management with oral rehydration therapy
    Hideki Taniguchi
    Department of Anesthesiology, Kanagawa Cancer Center, 1 1 2 Nakao, Asahi ku, Yokohama, 241 0815, Japan
    J Anesth 23:222-9. 2009
    ....
  30. pmc A novel technique for post-mastectomy breast irradiation utilising non-coplanar intensity-modulated radiation therapy
    M Koshy
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Br J Radiol 83:874-81. 2010
    The aim of this study was to investigate if non-coplanar intensity-modulated radiation therapy (IMRT) in the post-mastectomy setting can reduce the dose to normal structures and improve target coverage...
  31. doi Nipple-sparing mastectomy for breast cancer and risk-reducing surgery: the Memorial Sloan-Kettering Cancer Center experience
    Paulo de Alcantara Filho
    Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 18:3117-22. 2011
    Nipple-sparing mastectomy (NSM) has been gathering increased recognition as an alternative to more traditional mastectomy approaches. Initially, questions concerning its oncologic safety limited the use of NSM...
  32. doi Effects of mastectomy on shoulder and spinal kinematics during bilateral upper-limb movement
    Jack Crosbie
    Clinical Rehabilitation Sciences Research Group, Discipline of Physiotherapy, Faculty of Health Sciences, University of Sydney, PO Box 170, East Street, Lidcombe, New South Wales 1825, Australia
    Phys Ther 90:679-92. 2010
    ..Shoulder movement impairment is a commonly reported consequence of surgery for breast cancer...
  33. doi Surveillance, control, and prevention of surgical site infections in breast cancer surgery: a 5-year experience
    Diana Vilar-Compte
    Department of Infectious Diseases, National Cancer Institute, Tlalpan, Mexico
    Am J Infect Control 37:674-9. 2009
    ..We analyzed variations in surgical site infections (SSIs) during 5 years of a prospective surveillance program and investigated possible contributors to SSIs in a cohort of patients who underwent surgery for breast cancer...
  34. pmc Tailoring communication in consultations with women from high risk breast cancer families
    E A Lobb
    Medical Psychology Research Unit, Department of Psychological Medicine, University of Sydney, Sydney, New South Wales 2006, Australia
    Br J Cancer 87:502-8. 2002
    ..01) and breast cancer prevention with younger women (P=0.01). Prophylactic mastectomy was discussed more frequently with women with medical and allied health training (P=0...
  35. pmc Breast cancer among the oldest old: tumor characteristics, treatment choices, and survival
    Mara A Schonberg
    Beth Israel Deaconess Medical Center, 1309 Beacon, Office 202, Brookline, MA 02446, USA
    J Clin Oncol 28:2038-45. 2010
    ..Epidemiology and End Results-Medicare data set from 1992 to 2003 to examine tumor characteristics, treatments (mastectomy, breast-conserving surgery [BCS] with radiation therapy or alone, or no surgery), and outcomes of women age 80 ..
  36. doi Breast cancer recurrence following postmastectomy reconstruction compared to mastectomy with no reconstruction
    Sashank Reddy
    Department of Surgery, Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Ann Plast Surg 66:466-71. 2011
    ..This study compares incidence, detection, and management of recurrent breast cancer in a large series of patients treated with mastectomy alone or with mastectomy and various forms of reconstruction.
  37. ncbi Comparing two treatment methods for post mastectomy lymphedema: complex decongestive therapy alone and in combination with intermittent pneumatic compression
    S Haghighat
    Breast Research Department, Iranian Center for Breast Cancer, Tehran, Iran
    Lymphology 43:25-33. 2010
    ..that the use of CDT alone, or in combination with IPC significantly reduced limb volume in patients with post mastectomy lymphedema. CDT alone provided better results in both treatment phases...
  38. doi Defining the role for autologous breast reconstruction after mastectomy: social and oncologic implications
    Warren Matthew Rozen
    Jack Brockhoff Reconstructive Plastic Surgery Research Unit, Department of Anatomy and Cell Biology, The University of Melbourne, Parkville, Victoria, Australia
    Clin Breast Cancer 8:134-42. 2008
    ..performed to evaluate the interplay between the psychosocial need for breast reconstruction in patients after mastectomy and the issues surrounding its oncologic safety...
  39. pmc Trends in mastectomy rates at the Mayo Clinic Rochester: effect of surgical year and preoperative magnetic resonance imaging
    Rajini Katipamula
    Department of Oncology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Clin Oncol 27:4082-8. 2009
    ..We sought to analyze the trends in mastectomy rates and the relationship to preoperative MRI and surgical year at Mayo Clinic, Rochester, MN.
  40. doi The impact of skin-sparing mastectomy with immediate reconstruction in patients with Stage III breast cancer treated with neoadjuvant chemotherapy and postmastectomy radiation
    Roshan Prabhu
    Department of Radiation Oncology, Emory University, Atlanta, GA 30322, USA
    Int J Radiat Oncol Biol Phys 82:e587-93. 2012
    The safety and efficacy of skin-sparing mastectomy (SSM) with immediate reconstruction (IR) in patients with locally advanced breast cancer are unclear...
  41. ncbi Applicability of the nipple-areola complex-sparing mastectomy: a prediction model using mammography to estimate risk of nipple-areola complex involvement in breast cancer patients
    Amy K Schecter
    North Shore Long Island Jewish Health System, Department of General Surgery, New Hyde Park, NY, USA
    Ann Plast Surg 56:498-504; discussion 504. 2006
    ..cancer patients at lowest risk for neoplastic nipple-areola complex (NAC) involvement to offer total NAC-sparing mastectomy with immediate reconstruction...
  42. doi Percent positive axillary involvement predicts for the development of brain metastasis in high-risk patients with nonmetastatic breast cancer receiving post-mastectomy radiotherapy
    Ibtisam Lale Atahan
    Department of Radiation Oncology, Haceteppe University, Faculty of Medicine, Ankara, Turkey
    Breast J 14:245-9. 2008
    ..the predictive factors for brain metastasis in high-risk breast cancer patients receiving radiotherapy after mastectomy. Between January 1994 and 2002, the medical charts of nonmetastatic breast cancer patients receiving post-..
  43. doi Analyzing the risk of recurrence after mastectomy for DCIS: a new use for the USC/Van Nuys Prognostic Index
    Leah Kelley
    Department of Surgical Oncology, University of Southern California, Los Angeles, USA
    Ann Surg Oncol 18:459-62. 2011
    Patients with ductal carcinoma in situ (DCIS) who are treated with mastectomy seldom recur locally or with metastatic disease. When patients with DCIS recur with invasive cancer, they are upstaged and their lives are threatened...
  44. ncbi ACR appropriateness criteria on postmastectomy radiotherapy expert panel on radiation oncology-breast
    Marie E Taylor
    Washington University, Saint Louis, Missouri 63110 1032, USA
    Int J Radiat Oncol Biol Phys 73:997-1002. 2009
    This summary focuses on the role of postoperative radiation therapy in patients treated with modified radical mastectomy for invasive breast cancer, particularly in patients receiving systemic therapy.
  45. doi Prognostic significance of tumor grading and staging in mammary carcinomas with neuroendocrine differentiation
    Zhen Tian
    Department of Oral Pathology, Ninth People s Hospital, Shanghai Jiao Tong University, 200011 Shanghai, China
    Hum Pathol 42:1169-77. 2011
    ..Our data suggest that routine evaluation of Ki-67 proliferation index in these unusual tumors may provide more valuable information than mitotic count alone...
  46. ncbi Dosimetry around metallic ports in tissue expanders in patients receiving postmastectomy radiation therapy: an ex vivo evaluation
    Janaki Moni
    Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA
    Med Dosim 29:49-54. 2004
    ..Strategies designed to reduce the breast reconstruction complication rate in this clinical setting will need to focus on factors other than adjusting the dosimetry around the tissue expander metallic port...
  47. doi Cowden syndrome and reconstructive breast surgery: case reports and review of the literature
    E Ali
    Cambridge Breast Unit, Addenbrooke s University Hospital, Cambridge, UK
    J Plast Reconstr Aesthet Surg 64:545-9. 2011
    ..We briefly describe the syndrome and review management of the risk of CS-associated malignancies. Three cases of bilateral risk-reducing mastectomy and immediate breast reconstruction are described.
  48. doi A false positive for metastatic lymph nodes in the axillary region of a breast cancer patient following mastectomy
    Nobuko Fujiuchi
    Department of Breast Oncology, Saitama International Medical Center, Saitama Medical University, 1397 1 Yaname, Hidaka, Saitama, Japan
    Breast Cancer 18:141-4. 2011
    ..nodes that were diagnosed by PET/CT and ultrasonography in a 48-year-old breast cancer patient who had undergone mastectomy. The tumors, which were oval shaped and resembled lymph nodes, were detected by ultrasonography...
  49. pmc Long-term follow-up of breast cancer survivors with post-mastectomy pain syndrome
    L Macdonald
    Department of Anaesthesia, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
    Br J Cancer 92:225-30. 2005
    Post-mastectomy pain syndrome (PMPS) is a recognised complication of breast surgery although little is known about the long-term outcome of this chronic pain condition...
  50. ncbi Breast conservation surgery achieving>or=2 mm tumor-free margins results in decreased local-regional recurrence rates
    Charles Kunos
    Department of Radiation Oncology, University Hospitals of Cleveland, Cleveland, Ohio 44106 5000, USA
    Breast J 12:28-36. 2006
    ..Based on our findings, cosmetically acceptable tumor-free (>or=2 mm) surgical margins significantly reduce local in-breast and regional lymph node recurrences with fractionated radiation therapy, chemotherapy, and hormonal therapy...
  51. ncbi Use of abdominal quilting sutures for seroma prevention in TRAM flap reconstruction: a prospective, controlled trial
    Colleen McCarthy
    Division of Plastic Surgery, Department of Surgery, University of British Columbia, Vancouver, BC, Canada
    Ann Plast Surg 54:361-4. 2005
    ..Most importantly, there was no significant decrease in the incidence of seroma formation with the use of abdominal quilting sutures in this series...
  52. pmc Vocational rehabilitation services for patients with cancer: design of a feasibility study incorporating a pilot randomised controlled trial among women with breast cancer following surgery
    Richard G Kyle
    Cancer Care Research Centre, School of Nursing, Midwifery and Health, University of Stirling, Stirling, UK
    Trials 12:89. 2011
    ..A pilot randomised controlled trial among women with breast cancer has been designed to assess the feasibility of a larger definitive trial of VR services for people with cancer...
  53. ncbi Radiotherapy for breast cancer in patients undergoing breast reconstruction or augmentation
    Elzbieta Senkus-Konefka
    Department of Oncology and Radiotherapy, Medical University of Gdansk, Debinki 7, 80 211 Gdansk, Poland
    Cancer Treat Rev 30:671-82. 2004
    ..To minimize the risk of unfavourable outcome, the techniques and timing of both breast reconstruction and radiotherapy should be given meticulous attention...
  54. ncbi Randomized clinical trial on the preservation of the medial pectoral nerve following mastectomy due to breast cancer: impact on upper limb rehabilitation
    Andrea de Vasconcelos Gonçalves
    Department of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas UNICAMP, Sao Paulo, Brazil
    Sao Paulo Med J 127:117-21. 2009
    Systematic modifications to the surgical technique of mastectomy have been proposed with the objective of minimizing injuries to the pectoral nerves and their effects...
  55. ncbi Adjuvant radiotherapy after mastectomy for pT1-pT2 node negative (pN0) breast cancer: is it worth the effort?
    Mia Voordeckers
    Department of Radiotherapy, Academic Hospital V U B, Laarbeeklaan 101, 1090 Jette, Brussels, Belgium
    Radiother Oncol 68:227-31. 2003
    ..Since little data on the importance of RT in this subgroup are known, we reviewed the clinical records with regard to overall survival...
  56. ncbi Long-term survival outcomes following breast cancer surgery in Western Australia
    Katrina Spilsbury
    Western Australian Safety and Quality of Surgical Care Project, Centre for Health Services Research, School of Population Health, University of Western Australia, Crawley, Australia
    ANZ J Surg 75:625-30. 2005
    ..The aim of the present study was to investigate how hospital, social and demographic factors were associated with survival outcomes from surgically treated breast cancer for all women living in Western Australia...
  57. ncbi Decision aids and breast cancer: do they influence choice for surgery and knowledge of treatment options?
    Jennifer F Waljee
    Section of General Surgery and Section of Plastic Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI, USA
    J Clin Oncol 25:1067-73. 2007
    ..To describe the effect of decision aids on the choice for surgery and knowledge of surgical therapy among women with early-stage breast cancer...
  58. ncbi Antibiotic prophylaxis for preventing wound infection after breast surgery: a systematic review and metaanalysis
    Talar Tejirian
    Department of Surgery, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA 90027, USA
    J Am Coll Surg 203:729-34. 2006
  59. doi Measuring and managing patient expectations for breast reconstruction: impact on quality of life and patient satisfaction
    Andrea L Pusic
    Division of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Expert Rev Pharmacoecon Outcomes Res 12:149-58. 2012
    ..Specifically, we consider how systematic measurement and management of patient expectations may improve patient education, shared medical decision-making and patient perception of outcomes...
  60. pmc Patterns and correlates of adjuvant radiotherapy receipt after lumpectomy and after mastectomy for breast cancer
    Reshma Jagsi
    Department of Radiation Oncology, University of Michigan, UHB2C490, SPC 5010, 1500 E Medical Center Dr, Ann Arbor, MI 48109 5010, USA
    J Clin Oncol 28:2396-403. 2010
    ..To use patient self-report to provide more valid estimates of whether radiotherapy (RT) is underutilized than possible with registry data, as well as to evaluate for disparities and the influence of preferences and provider interactions...
  61. pmc Clinical practice guidelines for the care and treatment of breast cancer: 16. Locoregional post-mastectomy radiotherapy
    Pauline T Truong
    BC Cancer Agency Vancouver Island Centre
    CMAJ 170:1263-73. 2004
    To provide information and recommendations to assist women with breast cancer and their physicians in making decisions regarding the use of locoregional post-mastectomy radiotherapy (PMRT).
  62. pmc Survival analysis of cancer risk reduction strategies for BRCA1/2 mutation carriers
    Allison W Kurian
    Departments of Medicine, Health Research and Policy, and Radiology, Stanford University School of Medicine, Stanford, CA, USA
    J Clin Oncol 28:222-31. 2010
    ..We used decision analysis to simulate risk-reducing strategies in BRCA1/2 mutation carriers and to compare resulting survival probability and causes of death...
  63. ncbi Ultracision reduces acute blood loss but not seroma formation after mastectomy and axillary dissection: a pilot study
    A Adwani
    Breast Unit, Mayday University Hospital, London Road, Croydon, Surrey, UK
    Int J Clin Pract 60:562-4. 2006
    ..However, there was little difference between the two groups in terms of hospital stay, volume or duration of postoperative drainage or subsequent aspiration of seroma...
  64. doi Nipple-sparing mastectomy
    J E Rusby
    Academic Surgery, Royal Marsden NHS Foundation Trust, London, UK
    Br J Surg 97:305-16. 2010
    ..Nipple-sparing mastectomy aims to address this, but there is no consensus on its clinical application...
  65. ncbi Prospective analysis of psychosocial outcomes in breast reconstruction: one-year postoperative results from the Michigan Breast Reconstruction Outcome Study
    E G Wilkins
    Section of Plastic and Reconstructive Surgery, University of Michigan Health System, Ann Arbor 48109 0340, USA
    Plast Reconstr Surg 106:1014-25; discussion 1026-7. 2000
    ..among both patients and providers have led a growing number of women to seek breast reconstruction after mastectomy. Although investigators have documented the psychological, social, emotional, and functional benefits of breast ..
  66. ncbi Infectious complications following breast reconstruction with expanders and implants
    Maurice Y Nahabedian
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Plast Reconstr Surg 112:467-76. 2003
    ..29 times higher than when no lymph nodes were removed. No significant association between implant infection and age, diabetes, tobacco use, tumor stage, timing of implant insertion, or chemotherapy was found...
  67. ncbi Comparison of immediate and delayed free TRAM flap breast reconstruction in patients receiving postmastectomy radiation therapy
    N V Tran
    Department of Plastic Surgery, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Plast Reconstr Surg 108:78-82. 2001
    Tumor pathologic features and the extent of nodal involvement dictate whether radiation therapy is given after mastectomy for breast cancer...
  68. ncbi Risk-reduction mastectomy: clinical issues and research needs
    M Stefanek
    Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 93:1297-306. 2001
    Risk-reduction mastectomy (RRM), also known as bilateral prophylactic mastectomy, is a controversial clinical option for women who are at increased risk of breast cancer...
  69. ncbi Repeat breast-conserving surgery for in-breast local breast carcinoma recurrence: the potential role of partial breast irradiation
    Henry M Kuerer
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 100:2269-80. 2004
    b>Mastectomy is the current standard of care for in-breast local recurrence of breast carcinoma...
  70. ncbi Impact of IRB requirements on a multicenter survey of prophylactic mastectomy outcomes
    Sarah M Greene
    Group Health Cooperative Center for Health Studies, Seattle, WA 98101, USA
    Ann Epidemiol 16:275-8. 2006
    ..This study assesses the variability in requirements among six institutional review boards (IRBs) and the resulting protocol variations for a multicenter mailed survey...
  71. ncbi Necrotic complications after nipple- and areola-sparing mastectomy
    Andrzej L Komorowski
    Department of Surgical Oncology, Maria Skłodowska Curie Memorial Institute of Oncology, Cancer Centre, Krakow, Poland
    World J Surg 30:1410-3. 2006
    ..frequency and factors influencing necrotic complication in female patients undergoing nipple- and areola-sparing mastectomy. Nipple- and areola-sparing mastectomy has recently been shown to yield satisfactory results in a carefully ..
  72. pmc The psychosocial impact of bilateral prophylactic mastectomy: prospective study using questionnaires and semistructured interviews
    M B Hatcher
    Cancer Research Campaign Psychosocial Oncology Group, Bland Sutton Institute, Royal Free and University College Medical School, London W1P 7PL
    BMJ 322:76. 2001
    OBJECTIVES: To investigate the psychosocial impact of bilateral prophylactic mastectomy for women with increased risk of breast cancer and to identify, preoperatively, risk factors for postoperative distress...
  73. ncbi Epithelial lesions in prophylactic mastectomy specimens from women with BRCA mutations
    Noah D Kauff
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer 97:1601-8. 2003
    ..To investigate this hypothesis, the authors compared the prevalence of histopathologic lesions in prophylactic mastectomy (PM) specimens from women with BRCA mutations and in mastectomy specimens obtained at autopsy from an age and ..
  74. doi The value of latissimus dorsi flap with implant reconstruction for total mastectomy after conservative breast cancer surgery recurrence
    Cristina Garusi
    Division of Plastic Surgery, European Institute of Oncology, Via Ripamonti 435, 20141 Milano, Italy
    Breast 20:141-4. 2011
    Total mastectomy is usually indicated after breast conservative treatment cancer recurrence. Breast reconstruction in this group can be performed with many options...
  75. ncbi Early results of an endoscope-assisted subcutaneous mastectomy and reconstruction for breast cancer
    Kaoru Kitamura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Surgery 131:S324-9. 2002
    Subcutaneous mastectomy and reconstruction (SMR) is well established; however, most incisions are made directly on the breast, and the majority of patients care about visible scars even if they are satisfied with the reconstructed breast.
  76. ncbi Low locoregional recurrence rate among node-negative breast cancer patients with tumors 5 cm or larger treated by mastectomy, with or without adjuvant systemic therapy and without radiotherapy: results from five national surgical adjuvant breast and bowel
    Alphonse G Taghian
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistical Centers, Graduate School of Public Health, University of Pittsburgh, PA, USA
    J Clin Oncol 24:3927-32. 2006
    ..In this study, we assess patterns of locoregional failure (LRF) in LN-negative patients who underwent mastectomy, either with or without adjuvant chemotherapy or hormonal therapy and without postmastectomy radiation therapy (..
  77. ncbi Success of neoadjuvant chemotherapy in conversion of mastectomy to breast conservation surgery
    Paul Kaufmann
    Harbor UCLA Medical Center, Torrance, California, USA
    Am Surg 72:935-8. 2006
    ..the purpose of reducing tumor size and achieving breast conservation (BC) in individuals who initially require mastectomy. Our objective is to determine the success of NC in achieving BC in women who initially were not candidates for ..
  78. doi Minimising contralateral breast dose in post-mastectomy intensity-modulated radiotherapy by incorporating conformal electron irradiation
    Hans Paul van der Laan
    Department of Radiation Oncology, University Medical Center Groningen University of Groningen, Groningen, The Netherlands
    Radiother Oncol 94:235-40. 2010
    To assess the potential benefit of incorporating conformal electron irradiation in intensity-modulated radiotherapy (IMRT) for loco-regional post-mastectomy RT.
  79. ncbi Female BRCA mutation carriers with a preference for prophylactic mastectomy are more likely to participate an educational-support group and to proceed with the preferred intervention within 2 years
    Karin M Landsbergen
    Department of Human Genetics, Raboud University Nijmegen Medical Centre, Geert Grooteplein zuid 10, 6525 GA Nijmegen, The Netherlands
    Fam Cancer 9:213-20. 2010
    Women with a BRCA mutation face a complex choice between breast cancer surveillance and prophylactic mastectomy. We determined risk management preferences shortly after genetic test disclosure and mastectomy status after a median ..
  80. pmc Predictors of patients' choices for breast-conserving therapy or mastectomy: a prospective study
    S Molenaar
    Academic Medical Center, Department of Medical Psychology J4 401, PO Box 22 660, 1100 DD Amsterdam, The Netherlands
    Br J Cancer 90:2123-30. 2004
    ..of patients with breast cancer, and to identify predictors of undergoing breast-conserving therapy (BCT) or mastectomy (MT). Consecutive patients with stage I/II breast cancer were eligible...
  81. ncbi TRAM flap for immediate post mastectomy reconstruction: comparison between pedicled and free transfer
    Mahmoud M Bassiouny
    The Department of Surgical Oncology, National Cancer Institute, Cairo University
    J Egypt Natl Canc Inst 17:231-8. 2005
    Breast reconstruction after mastectomy is primarily carried out to improve the patients' quality of life. The most commonly used autologous tissue for reconstruction is the transverse rectus abdominis musculocutaneous flap (TRAM)...
  82. ncbi Physical activity for the affected limb and arm lymphedema after breast cancer surgery. A prospective, randomized controlled trial with two years follow-up
    Ase Sagen
    Department of Breast and Endocrine Surgery, Oslo University Hospital, Ullevaal, Norway
    Acta Oncol 48:1102-10. 2009
    ..CONCLUSION. Patients that undergo breast cancer surgery with axillary lymph node dissection should be encouraged to maintain physical activity in their daily lives without restrictions and without fear of developing ALE...
  83. pmc Are breast cancer screening programmes increasing rates of mastectomy? Observational study
    Eugenio Paci
    Unit of Epidemiology, Centre for the Study and Prevention of Cancer CSPO, Via di S Salvi 12, 50135 Florence, Italy
    BMJ 325:418. 2002
  84. doi Nipple-sparing mastectomy: initial experience at the Memorial Sloan-Kettering Cancer Center and a comprehensive review of literature
    Carlos A Garcia-Etienne
    Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, New York NY 10021, USA
    Breast J 15:440-9. 2009
    Success achieved with skin-sparing mastectomy has led surgeons to reconsider the necessity of nipple-areola complex removal...
  85. doi Nipple areola skin-sparing mastectomy with immediate transverse rectus abdominis musculocutaneous flap reconstruction is an oncologically safe procedure: a single center study
    Hee Jeong Kim
    Department of Surgery, College of Medicine, Asan Medical Center, University of Ulsan, Seoul, Korea
    Ann Surg 251:493-8. 2010
    The present study evaluated the oncological safety and technical outcomes following nipple areola skin-sparing mastectomy (NASSM), skin-sparing mastectomy (SSM), and mastectomy.
  86. doi Patient satisfaction following nipple-sparing mastectomy and immediate breast reconstruction: an 8-year outcome study
    Risal Djohan
    Department of Plastic Surgery, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
    Plast Reconstr Surg 125:818-29. 2010
    Nipple-sparing mastectomy has become an accepted treatment for appropriately selected breast cancers. No reports have correlated patient satisfaction following nipple-sparing mastectomy with objective observer assessments.
  87. ncbi Locoregional recurrence rates and prognostic factors for failure in node-negative patients treated with mastectomy: implications for postmastectomy radiation
    Reshma Jagsi
    Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, 100 Blossom Street, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 62:1035-9. 2005
    ..Survival appears improved in patients at higher risk for LRR. This study addresses whether subsets of node-negative patients with sufficiently high risk of LRR might benefit from PMRT...
  88. ncbi Dosimetric comparison of conventional and forward-planned intensity-modulated techniques for comprehensive locoregional irradiation of post-mastectomy left breast cancers
    Matthew L Cavey
    Department of Radiation Oncology, University of Texas Medical Branch, Galveston, TX 77555 0711, USA
    Med Dosim 30:107-16. 2005
    ..The fIMRT technique demonstrated the ability to maintain the advantage of each of the other 2 techniques: reducing the dose to OARs, as with PE, and providing superior target volume coverage, as with PWT...
  89. ncbi Satisfaction after contralateral prophylactic mastectomy: the significance of mastectomy type, reconstructive complications, and body appearance
    Marlene H Frost
    Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 23:7849-56. 2005
    Contralateral prophylactic mastectomy (CPM) is one option for reducing the risk of a second breast cancer in women with a personal and family history of breast cancer...
  90. doi Are mastectomy rates really increasing in the United States?
    Elizabeth B Habermann
    University of Minnesota andVeterans Affairs Medical Center, Minneapolis, MN, USA
    J Clin Oncol 28:3437-41. 2010
    ..Institutes of Health Consensus Statement in 1990, breast-conserving surgery (BCS) became more common while mastectomy rates decreased...
  91. ncbi Do intraoperative analgesics influence breast cancer recurrence after mastectomy? A retrospective analysis
    Patrice Forget
    Department of Anesthesiology, Universite Catholique de Louvain, Louvain la Neuve, Belgium
    Anesth Analg 110:1630-5. 2010
    ..We retrospectively reviewed our series of breast cancer surgery patients...
  92. ncbi Contentment with quality of life among breast cancer survivors with and without contralateral prophylactic mastectomy
    Ann M Geiger
    Research and Evaluation Department, Kaiser Permanente Southern California, Pasadena, USA
    J Clin Oncol 24:1350-6. 2006
    ..To understand psychosocial outcomes after prophylactic removal of the contralateral breast in women with unilateral breast cancer...
  93. pmc Preoperative dexamethasone reduces postoperative pain, nausea and vomiting following mastectomy for breast cancer
    Jorge Gómez-Hernández
    Breast Tumor Clinic Oncologic Institute of Jalisco, Health Secretary, CalleCoronel Calderon 715, Colonia El Retiro, Postal code 44280, Guadalajara, Jalisco, Mexico
    BMC Cancer 10:692. 2010
    ..We evaluated the efficacy of preoperative dexamethasone in ameliorating postoperative nausea and vomiting (PONV), and pain after mastectomy.
  94. ncbi Breast cancer local recurrence after mastectomy and TRAM flap reconstruction: incidence and treatment options
    Michael A Howard
    Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 117:1381-6. 2006
    ..The purpose of this study was to examine the incidence of local recurrence of breast cancer after TRAM flap breast reconstruction, evaluate treatment modalities, and determine outcomes in such cases...
  95. doi Use of tumescent mastectomy technique as a risk factor for native breast skin flap necrosis following immediate breast reconstruction
    Yoon S Chun
    Department of Surgery, Brigham and Women s Hospital, Faulkner Hospital, Boston, MA, USA
    Am J Surg 201:160-5. 2011
    Native breast skin flap necrosis is a complication that can result from ischemic injury following mastectomy and can compromise immediate breast reconstruction...
  96. doi Prevention of seroma formation after mastectomy and axillary dissection by lymph vessel ligation and dead space closure: a randomized trial
    Yiping Gong
    Department of Oncological Surgery, Zhongnan Hospital, Wuhan University, Hubei, China
    Am J Surg 200:352-6. 2010
    ..We aimed to reduce the incidence of seroma formation by altering surgical technique...
  97. doi Decision making regarding prophylactic mastectomy: stability of preferences and the impact of anticipated feelings of regret
    Sandra van Dijk
    Department of Medical Psychology, Leiden University Medical Center, Pieter de la Court Building, Postbox 9555, 2300 RB Leiden, The Netherlands
    J Clin Oncol 26:2358-63. 2008
    ..difficult choices to manage their breast cancer risk; one of these choices is whether to opt for prophylactic mastectomy. Few data are available about this decision-making process...
  98. doi Nipple-sparing mastectomy
    Scott L Spear
    Department of Plastic Surgery, Georgetown University Hospital, Washington, DC 20007, USA
    Plast Reconstr Surg 123:1665-73. 2009
    The debate over nipple-sparing mastectomy continues to evolve...
  99. pmc Genetic counselling and the intention to undergo prophylactic mastectomy: effects of a breast cancer risk assessment
    S van Dijk
    Department of Medical Decision Making, Leiden University Medical Center, PO Box 9600, The Netherlands
    Br J Cancer 88:1675-81. 2003
    Scientific reports suggest that women at risk for familial breast cancer may benefit from prophylactic mastectomy. However, few data are available about how women decide upon this clinical option, and in particular, what role an objective ..
  100. ncbi Terminal duct lobular units are scarce in the nipple: implications for prophylactic nipple-sparing mastectomy: terminal duct lobular units in the nipple
    Alan J Stolier
    Tulane University Department of Surgery and Omega Hospital, 2525 Severn Ave, New Orleans, LA, USA
    Ann Surg Oncol 15:438-42. 2008
    The use of nipple-sparing mastectomy (NSM) for both breast cancer treatment and risk reduction is increasing. There is no randomized data comparing nipple-sparing mastectomy with standard mastectomy techniques...
  101. pmc Sequencing chemotherapy and radiotherapy in locoregional advanced breast cancer patients after mastectomy - a retrospective analysis
    Marc D Piroth
    Department of Radiation Oncology, RWTH Aachen University Hospital, Aachen, Germany
    BMC Cancer 8:114. 2008
    ..This retrospective analysis aimed to assess the role of sequencing in patients after mastectomy because of advanced locoregional disease.

Research Grants80

  1. Cellular Mechanisms of Lymphatic Muscle Contractility
    Michael Davis; Fiscal Year: 2009
    ..in the US currently suffer from some form of lymphedema, including a high percentage of patients recovering from mastectomy or reconstructive surgery...
  2. Cellular Mechanisms of Lymphatic Muscle Contractility
    MICHAEL JOHN DAVIS; Fiscal Year: 2010
    ..in the US currently suffer from some form of lymphedema, including a high percentage of patients recovering from mastectomy or reconstructive surgery...
  3. A new class of biodegradable synthetic biomaterial for seroma prevention
    Michael Craven; Fiscal Year: 2012
    ..vivo) into biocompatible products, and successful elimination of seroma in an accepted animal model of radical mastectomy. Phase I efforts will focus on determining the range of efficacy of MPEG-pDHA in vivo and on evaluating its ..
  4. VARIABLES AFFECTING OSTOMY PATIENT OUTCOME
    Debra Jackson; Fiscal Year: 1991
    ..g., diabetes, hypertension, transplantation, mastectomy)...
  5. Managed Care Penetration and Cancer Care
    Edward Guadagnoli; Fiscal Year: 2002
    ..care penetration and the use of treatments that are equally effective but that differ in cost for breast cancer (mastectomy versus breast conserving surgery) and prostate cancer (conservative management versus surgery or radiation ..
  6. Managed Care Penetration and Cancer Care
    Edward Guadagnoli; Fiscal Year: 2001
    ..care penetration and the use of treatments that are equally effective but that differ in cost for breast cancer (mastectomy versus breast conserving surgery) and prostate cancer (conservative management versus surgery or radiation ..
  7. Managed Care Penetration and Cancer Care
    Nancy Keating; Fiscal Year: 2003
    ..care penetration and the use of treatments that are equally effective but that differ in cost for breast cancer (mastectomy versus breast conserving surgery) and prostate cancer (conservative management versus surgery or radiation ..
  8. Presurgery Hypnosis--Benefits Analysis in Breast Cancer
    Guy Montgomery; Fiscal Year: 2002
    ..o achieve these aims, 140 breast cancer patients scheduled for mastectomy will be randomly assigned to a hypnosis intervention group or an attention control group...
  9. Presurgery Hypnosis--Benefits Analysis in Breast Cancer
    Guy Montgomery; Fiscal Year: 2001
    ..o achieve these aims, 140 breast cancer patients scheduled for mastectomy will be randomly assigned to a hypnosis intervention group or an attention control group...
  10. TRAUMATIC PAINFUL NEUROPATHY AND CALCIUM SIGNALING
    Quinn Hogan; Fiscal Year: 2002
    Nerve injury results in chronic pain following surgery, such as amputation, thoracotomy and mastectomy, as well as in cancer, degenerative conditions and metabolic diseases...
  11. TRAUMATIC PAINFUL NEUROPATHY AND CALCIUM SIGNALING
    Quinn Hogan; Fiscal Year: 2003
    Nerve injury results in chronic pain following surgery, such as amputation, thoracotomy and mastectomy, as well as in cancer, degenerative conditions and metabolic diseases...
  12. TRAUMATIC PAINFUL NEUROPATHY AND CALCIUM SIGNALING
    Quinn Hogan; Fiscal Year: 2004
    Nerve injury results in chronic pain following surgery, such as amputation, thoracotomy and mastectomy, as well as in cancer, degenerative conditions and metabolic diseases...
  13. TRAUMATIC PAINFUL NEUROPATHY AND CALCIUM SIGNALING
    Quinn Hogan; Fiscal Year: 2001
    Nerve injury results in chronic pain following surgery, such as amputation, thoracotomy and mastectomy, as well as in cancer, degenerative conditions and metabolic diseases...
  14. Presurgery Hypnosis--Benefits Analysis in Breast Cancer
    Guy Montgomery; Fiscal Year: 2003
    ..o achieve these aims, 140 breast cancer patients scheduled for mastectomy will be randomly assigned to a hypnosis intervention group or an attention control group...
  15. STEROID METABOLISM AND ACTION IN CANCER
    Mortimer Levitz; Fiscal Year: 1993
    ..The tissues will be dissected promptly from breast obtained at mastectomy. This model, though subject to interpretation, eliminates the troublesome features of differential clearance and ..
  16. MULTILEVEL COMPLIANCE MODEL OF BREAST CANCER TREATMENTS
    Mary Fennell; Fiscal Year: 1999
    ..primary treatment has been breast conserving surgery (BCS) plus radiation therapy (RT), or modified radical mastectomy. Nonetheless, geographic and hospital variation in the use of BCS, and a high portion of women, particularly ..
  17. A Decision Making Framework for Contralateral Prophylactic Mastectomy
    Patricia A Parker; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): The use of contralateral prophylactic mastectomy (CPM) in the United States among patients with unilateral invasive breast cancer has increased by 150% from 1993 to 2003 with no evidence of a plateau ..
  18. Presurgery Hypnosis in Breast Cancer: Benefits Analysis
    Guy Montgomery; Fiscal Year: 2005
    ..goal is to establish the relative efficacy and cost of "live" and recorded presurgical hypnosis interventions in mastectomy patients...
  19. Presurgery Hypnosis in Breast Cancer: Benefits Analysis
    Guy Montgomery; Fiscal Year: 2004
    ..goal is to establish the relative efficacy and cost of "live" and recorded presurgical hypnosis interventions in mastectomy patients...
  20. Presurgery Hypnosis in Breast Cancer: Benefits Analysis
    Guy Montgomery; Fiscal Year: 2006
    ..goal is to establish the relative efficacy and cost of "live" and recorded presurgical hypnosis interventions in mastectomy patients...
  21. PRIMARY BREAST CANCER THERAPY GROUP
    Richard Margolese; Fiscal Year: 1990
    ..We have made a major contribution to protocol 4, evaluating the relative efficacy of radical mastectomy versus total mastectomy with radiation, versus total mastectomy alone, in patients with clinically negative ..
  22. PRIMARY BREAST CANCER THERAPY GROUP
    Henry Shibata; Fiscal Year: 1980
    ..randomized clinical trial that: 1) Local therapy as indicated by Protocol B-04, a comparison of Radical Mastectomy versus Total Mastectomy versus Total Mastectomy with postoperative irradiation has no significant influence on ..
  23. Soy-rich diet for preventing chronic post breast cancer surgery pain
    Yoram Shir; Fiscal Year: 2009
    ..postmenopausal status and the planned type of surgery, i.e., formal mastectomy vs. breast-conserving surgery...
  24. Prophylactic, risk-reducing surgery in BRCA-positive women: sexual functioning a
    Sharon Tollin; Fiscal Year: 2010
    ..Prophylactic surgeries including bilateral prophylactic mastectomy (BPM) and bilateral prophylactic salpingo-oophorectomy (BPSO) are utilized to substantially decrease cancer risk...
  25. Use of Regression Models in Cost-effectiveness Analysis
    Joseph Gardiner; Fiscal Year: 2005
    ..artery bypass surgery, percutaneous coronary intervention); (b) for women with breast cancer, undergoing mastectomy or lumpectomy; (c) for patients with colorectal cancer undergoing colectomy...
  26. Use of Regression Models in Cost-effectiveness Analysis
    Joseph Gardiner; Fiscal Year: 2006
    ..artery bypass surgery, percutaneous coronary intervention); (b) for women with breast cancer, undergoing mastectomy or lumpectomy; (c) for patients with colorectal cancer undergoing colectomy...
  27. Use of Regression Models in Cost-effectiveness Analysis
    Joseph Gardiner; Fiscal Year: 2004
    ..artery bypass surgery, percutaneous coronary intervention); (b) for women with breast cancer, undergoing mastectomy or lumpectomy; (c) for patients with colorectal cancer undergoing colectomy...
  28. Screening for Breast Cancer Using Molecular Signatures
    Timothy Yeatman; Fiscal Year: 2004
    ..signatures, within zones of histologically non-malignant breast tissue adjacent to invasive cancer derived from mastectomy specimens (n = 100). Specific Aim II...
  29. Screening for Breast Cancer Using Molecular Signatures
    Timothy Yeatman; Fiscal Year: 2007
    ..signatures, within zones of histologically non-malignant breast tissue adjacent to invasive cancer derived from mastectomy specimens (n = 100). Specific Aim II...
  30. Screening for Breast Cancer Using Molecular Signatures
    Timothy Yeatman; Fiscal Year: 2005
    ..signatures, within zones of histologically non-malignant breast tissue adjacent to invasive cancer derived from mastectomy specimens (n = 100). Specific Aim II...
  31. Screening for Breast Cancer Using Molecular Signatures
    Timothy Yeatman; Fiscal Year: 2003
    ..signatures, within zones of histologically non-malignant breast tissue adjacent to invasive cancer derived from mastectomy specimens (n = 100). Specific Aim II...
  32. Screening for Breast Cancer Using Molecular Signatures
    Timothy Yeatman; Fiscal Year: 2006
    ..signatures, within zones of histologically non-malignant breast tissue adjacent to invasive cancer derived from mastectomy specimens (n = 100). Specific Aim II...
  33. PRIMARY BREAST CANCER THERAPY GROUP (NSABP)
    Richard Margolese; Fiscal Year: 1980
    ..We have made a major contribution to Protocol 4, a comparison of Radical Mastectomy versus Total Mastectomy with Radiation vs. Total Mastectomy alone...
  34. Wwox as a Critical Signal Mediator in Breast Cancer
    Kay Huebner; Fiscal Year: 2006
    ..cancers will be sensitive to tamoxifen therapy; map the extent of WWOX promoter methylation throughout cancerous mastectomy specimens, as a marker for breast cancer field cancerization...
  35. Fasting Glucose in Long-Term Breast Cancer Survival
    Paola Muti; Fiscal Year: 2005
    ..who received complete resection of the neoplastic lesion (lumpectomy with margin clear of invasive cancer or mastectomy)...
  36. Clinical/pathologic predictors for recurrence after DCIS
    Laurel Habel; Fiscal Year: 2003
    ..Consequently, treatment decisions are difficult and up to 40% of DCIS patients will have a mastectomy. We propose to conduct a nested case-control study to identify clinical and pathologic factors that could be ..
  37. Fasting Glucose in Long-Term Breast Cancer Survival
    Paola Muti; Fiscal Year: 2004
    ..who received complete resection of the neoplastic lesion (lumpectomy with margin clear of invasive cancer or mastectomy)...
  38. Wwox as a Critical Signal Mediator in Breast Cancer
    Kay Huebner; Fiscal Year: 2007
    ..cancers will be sensitive to tamoxifen therapy; map the extent of WWOX promoter methylation throughout cancerous mastectomy specimens, as a marker for breast cancer field cancerization...
  39. Surgical Treament for Early State Breast Cancer
    Steven Katz; Fiscal Year: 2002
    ..Although many women with DCIS appear to be ideal candidates for breast conserving therapy, mastectomy rates for this particular form of breast cancer remain high...
  40. Surgical Treament for Early State Breast Cancer
    Steven Katz; Fiscal Year: 2001
    ..Although many women with DCIS appear to be ideal candidates for breast conserving therapy, mastectomy rates for this particular form of breast cancer remain high...
  41. Surgical Treament for Early State Breast Cancer
    Steven Katz; Fiscal Year: 2003
    ..Although many women with DCIS appear to be ideal candidates for breast conserving therapy, mastectomy rates for this particular form of breast cancer remain high...
  42. Feasibility of optoacoustic tomography in backward mode
    Alexander Oraevsky; Fiscal Year: 2002
    ..Comprehensive tests in phantoms resembling properties of the breast with tumors, extensive studies in mastectomy specimen surgically excised from the breast cancer patients and pilot clinical studies on breast cancer patients ..
  43. NSABP B-27--Preoperative doxorubicin/cyclophosphamide/docetaxel in breast cancer
    Scott Kurtzman; Fiscal Year: 2000
    ..respectively, every 21 days followed by surgery (lumpectomy and axillary node dissection, or modified radical mastectomy)...
  44. Feasibility of optoacoustic tomography in backward mode
    Alexander Oraevsky; Fiscal Year: 2004
    ..Comprehensive tests in phantoms resembling properties of the breast with tumors, extensive studies in mastectomy specimen surgically excised from the breast cancer patients and pilot clinical studies on breast cancer patients ..
  45. PRIMARY BREAST CANCER THERAPY GROUP--NSABP
    Nicholas Robert; Fiscal Year: 1990
    ..38 patients per year based on the opening of NSABP breast protocols to patients who have undergone segmental mastectomy, education of surgeons regarding referral of node-negative and intraductal breast cancer patients and recent ..
  46. Feasibility of optoacoustic tomography in backward mode
    Alexander Oraevsky; Fiscal Year: 2003
    ..Comprehensive tests in phantoms resembling properties of the breast with tumors, extensive studies in mastectomy specimen surgically excised from the breast cancer patients and pilot clinical studies on breast cancer patients ..
  47. COMMUNITY CLINICAL ONCOLOGY PROGRAM
    Janardan Khandekar; Fiscal Year: 1993
    ..These include: a NCI-funded study of low-fat diet in postmenopausal breast cancer, treatment of post-mastectomy arm lymphedema; a Stop Smoking Clinic, and prevention of oral complications from chemotherapy and bereavement ..
  48. PRIMARY BREAST CANCER THERAPY GROUP (NSABP)
    David Plotkin; Fiscal Year: 1980
    ..the worth of three-drug chemotherapy (L-PAM, 5-FU and Methotrexate) with two-drug chemotherapy segmental mastectomy with and without breast radiation with total mastectomy plus axillary dissection...
  49. Breast Cancer Treatment Effectiveness in Older Women
    Rebecca Silliman; Fiscal Year: 2003
    ..primary tumor therapy (breast conserving surgery, axillary dissection, and radiation therapy or modified radical mastectomy) versus other than standard therapy in preventing breast cancer recurrences and mortality, adjusting for co-..
  50. Decision-making regarding radiation therapy in breast cancer"
    RINAA PUNGLIA; Fiscal Year: 2009
    ..the SEER-Medicare database, by analyzing the factors that predict for the receipt of radiation therapy after mastectomy, The selection of patients who benefit from the addition of radiation in this setting is the subject of ..
  51. Primary Hormonal Therpay for DCIS of the Breast
    E Hwang; Fiscal Year: 2006
    ..interventions such as hormonal therapy could be instituted in the place of lumpectomy and radiation or mastectomy for at least a subset of patients...
  52. Decision-making regarding radiation therapy in breast cancer"
    Rinaa S Punglia; Fiscal Year: 2010
    ..the SEER-Medicare database, by analyzing the factors that predict for the receipt of radiation therapy after mastectomy, The selection of patients who benefit from the addition of radiation in this setting is the subject of ..
  53. Decision-making regarding radiation therapy in breast cancer"
    RINAA PUNGLIA; Fiscal Year: 2007
    ..the SEER-Medicare database, by analyzing the factors that predict for the receipt of radiation therapy after mastectomy, The selection of patients who benefit from the addition of radiation in this setting is the subject of ..
  54. Decision-making regarding radiation therapy in breast cancer"
    RINAA PUNGLIA; Fiscal Year: 2006
    ..the SEER-Medicare database, by analyzing the factors that predict for the receipt of radiation therapy after mastectomy, The selection of patients who benefit from the addition of radiation in this setting is the subject of ..
  55. PRIMARY BREAST CANCER THERAPY GROUP
    Roger Poisson; Fiscal Year: 1990
    ..a trial of breast preservation (protocol 6) is underway within the NSABP to compare the value of segmental mastectomy with and without breast irradiation vs. total mastectomy...
  56. Primary Hormonal Therpay for DCIS of the Breast
    E Hwang; Fiscal Year: 2005
    ..interventions such as hormonal therapy could be instituted in the place of lumpectomy and radiation or mastectomy for at least a subset of patients...
  57. Primary Hormonal Therapy for DCIS of the Breast
    E Hwang; Fiscal Year: 2004
    ..interventions such as hormonal therapy could be instituted in the place of lumpectomy and radiation or mastectomy for at least a subset of patients...
  58. BEHAVIORAL CONTROL OF PAIN WITH CANCER TREATMENT
    William Redd; Fiscal Year: 1980
    ..Twenty-four mastectomy patients will be asked to keep hourly records (during the day of treatment) of nausea (as measured by a visual ..
  59. Primary Hormonal Therapy for DCIS of the Breast
    EUN SIL HWANG; Fiscal Year: 2007
    ..interventions such as hormonal therapy could be instituted in the place of lumpectomy and radiation or mastectomy for at least a subset of patients...
  60. Hospital and County-Level Predictors of Immediate Breast Reconstruction Post-Mast
    CATHERINE ANN RICHARDS; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Immediate breast reconstruction post-mastectomy is underutilized and there are significant racial, economic and geographic disparities...
  61. MBSR Symptom Cluster Trial for Breast Cancer Survivors
    Cecile A Lengacher; Fiscal Year: 2010
    ..clinical trial of 330 women with Stage 0, I, II, and III breast cancer who have undergone lumpectomy and/or mastectomy, and are within 2 years of completion of treatment with adjuvant radiation and/or chemotherapy...
  62. PRIMARY BREAST CANCER THERAPY GROUP
    Henry Shibata; Fiscal Year: 1990
    ..P. PROTOCOL B-06: As the follow-up study to Protocol B-04, this protocol was designed to determine whether Total Mastectomy (the least traumatizing arm in B-04) is comparable to Segmental Mastecomy plus Breast Irradiation or Segmental ..
  63. MBSR Symptom Cluster Trial for Breast Cancer Survivors
    Cecile Lengacher; Fiscal Year: 2009
    ..clinical trial of 330 women with Stage 0, I, II, and III breast cancer who have undergone lumpectomy and/or mastectomy, and are within 2 years of completion of treatment with adjuvant radiation and/or chemotherapy...
  64. Intra-operative specimen tomosynthesis for margin assessment in breast surgery
    EMRE TOKER; Fiscal Year: 2009
    ..shown no significant difference in survival rates between women with breast cancer who are treated with radical mastectomy versus those treated with lumpectomy in conjunction with radiation therapy...
  65. MBSR Symptom Cluster Trial for Breast Cancer Survivors
    Cecile A Lengacher; Fiscal Year: 2010
    ..clinical trial of 330 women with Stage 0, I, II, and III breast cancer who have undergone lumpectomy and/or mastectomy, and are within 2 years of completion of treatment with adjuvant radiation and/or chemotherapy...
  66. Isolation of human tumor cells in dormant cancer
    Jonathan Uhr; Fiscal Year: 2006
    ..the presence of circulating tumor cells (CTCs) in patients with prior breast cancer who are 7-22 years post-mastectomy and who have no evidence of disease (NED), thus very likely to be in a tumor dormancy state...
  67. Isolation of human tumor cells in dormant cancer
    Jonathan Uhr; Fiscal Year: 2005
    ..the presence of circulating tumor cells (CTCs) in patients with prior breast cancer who are 7-22 years post-mastectomy and who have no evidence of disease (NED), thus very likely to be in a tumor dormancy state...
  68. PRIMARY BREAST CANCER THERAPY GROUP
    Roger Poisson; Fiscal Year: 1980
    ..6, which is a protocol to compare worth of segmental mastectomy with and without breast radiation with total mastectomy plus axillary dissection...
  69. Isolation of human tumor cells in dormant cancer
    Jonathan Uhr; Fiscal Year: 2007
    ..the presence of circulating tumor cells (CTCs) in patients with prior breast cancer who are 7-22 years post-mastectomy and who have no evidence of disease (NED), thus very likely to be in a tumor dormancy state...
  70. Feasibility of CT in high risk breast cancer patients
    John Boone; Fiscal Year: 2001
    ..the potential of dedicated breast CT using computer simulation techniques coupled with CT of cadaver breasts and mastectomy specimens...
  71. Feasibility of CT in high risk breast cancer patients
    John Boone; Fiscal Year: 2002
    ..the potential of dedicated breast CT using computer simulation techniques coupled with CT of cadaver breasts and mastectomy specimens...
  72. Feasibility of CT in high risk breast cancer patients
    John Boone; Fiscal Year: 2003
    ..the potential of dedicated breast CT using computer simulation techniques coupled with CT of cadaver breasts and mastectomy specimens...