mastectomy

Summary

Top Publications

  1. ncbi Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
    Edward H Romond
    National Surgical Adjuvant Breast and Bowel Project, Pittsburgh, USA
    N Engl J Med 353:1673-84. 2005
  2. ncbi Ductal carcinoma in situ of the breast
    Harold J Burstein
    Division of Medical Oncology and the Department of Medicine, Dana Farber Cancer Institute, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 350:1430-41. 2004
  3. pmc Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile
    K Graham
    Boston University School of Medicine and Boston Medical Center, MA, USA
    Br J Cancer 102:1284-93. 2010
  4. ncbi Is the benefit of postmastectomy irradiation limited to patients with four or more positive nodes, as recommended in international consensus reports? A subgroup analysis of the DBCG 82 b&c randomized trials
    Marie Overgaard
    Department of Oncology, Aarhus University Hospital, Denmark
    Radiother Oncol 82:247-53. 2007
  5. doi Breast reconstruction after surgery for breast cancer
    Peter G Cordeiro
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    N Engl J Med 359:1590-601. 2008
  6. ncbi Evaluation of the isoflurane-sparing effects of lidocaine and fentanyl during surgery in dogs
    Paulo V M Steagall
    Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, Sao Paulo State University, Botucatu, SP 18618 000, Brazil
    J Am Vet Med Assoc 229:522-7. 2006
  7. ncbi Granulomatous lobular mastitis: a complex diagnostic and therapeutic problem
    Alper Akcan
    Department of General Surgery, Erciyes University Medical Faculty, Kayseri, Turkey
    World J Surg 30:1403-9. 2006
  8. ncbi Lung carcinoma after radiation therapy in women treated with lumpectomy or mastectomy for primary breast carcinoma
    Lydia B Zablotska
    Department of Epidemiology, Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Cancer 97:1404-11. 2003
  9. pmc Lymphedema and quality of life in breast cancer survivors: the Iowa Women's Health Study
    Rehana L Ahmed
    Department of Dermatology, University of Minnesota, Minneapolis, MN 55455 0392, USA
    J Clin Oncol 26:5689-96. 2008
  10. pmc Breast cancer among the oldest old: tumor characteristics, treatment choices, and survival
    Mara A Schonberg
    Beth Israel Deaconess Medical Center, 1309 Beacon, Office 202, Brookline, MA 02446, USA
    J Clin Oncol 28:2038-45. 2010

Detail Information

Publications340 found, 100 shown here

  1. ncbi Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
    Edward H Romond
    National Surgical Adjuvant Breast and Bowel Project, Pittsburgh, USA
    N Engl J Med 353:1673-84. 2005
    ..We present the combined results of two trials that compared adjuvant chemotherapy with or without concurrent trastuzumab in women with surgically removed HER2-positive breast cancer...
  2. ncbi Ductal carcinoma in situ of the breast
    Harold J Burstein
    Division of Medical Oncology and the Department of Medicine, Dana Farber Cancer Institute, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 350:1430-41. 2004
  3. pmc Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile
    K Graham
    Boston University School of Medicine and Boston Medical Center, MA, USA
    Br J Cancer 102:1284-93. 2010
    ..between breast cancer patients and usual-risk controls undergoing reduction mammoplasty (RM), and that gene expression in NlEpi from cancer-free prophylactic mastectomy (PM) samples from high-risk women would resemble HN gene expression.
  4. ncbi Is the benefit of postmastectomy irradiation limited to patients with four or more positive nodes, as recommended in international consensus reports? A subgroup analysis of the DBCG 82 b&c randomized trials
    Marie Overgaard
    Department of Oncology, Aarhus University Hospital, Denmark
    Radiother Oncol 82:247-53. 2007
    ..A subgroup analysis of the DBCG 82 b&c trials was performed to evaluate the loco-regional recurrence rate and survival in relation to number of positive nodes...
  5. doi Breast reconstruction after surgery for breast cancer
    Peter G Cordeiro
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    N Engl J Med 359:1590-601. 2008
  6. ncbi Evaluation of the isoflurane-sparing effects of lidocaine and fentanyl during surgery in dogs
    Paulo V M Steagall
    Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, Sao Paulo State University, Botucatu, SP 18618 000, Brazil
    J Am Vet Med Assoc 229:522-7. 2006
    ..To evaluate the isoflurane-sparing effects of lidocaine and fentanyl administered by constant rate infusion (CRI) during surgery in dogs...
  7. ncbi Granulomatous lobular mastitis: a complex diagnostic and therapeutic problem
    Alper Akcan
    Department of General Surgery, Erciyes University Medical Faculty, Kayseri, Turkey
    World J Surg 30:1403-9. 2006
    ..The purpose of this study is to evaluate diagnostic difficulties and discuss the outcome of surgical treatment in a series of 21 patients with granulomatous lobular mastitis...
  8. ncbi Lung carcinoma after radiation therapy in women treated with lumpectomy or mastectomy for primary breast carcinoma
    Lydia B Zablotska
    Department of Epidemiology, Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Cancer 97:1404-11. 2003
    Prior studies have demonstrated that women who receive adjuvant radiation therapy (RT) after mastectomy for breast carcinoma have an increased risk of a second primary lung carcinoma after 10 years, but, to the authors' knowledge, the ..
  9. pmc Lymphedema and quality of life in breast cancer survivors: the Iowa Women's Health Study
    Rehana L Ahmed
    Department of Dermatology, University of Minnesota, Minneapolis, MN 55455 0392, USA
    J Clin Oncol 26:5689-96. 2008
    ..The impact of lymphedema or related arm symptoms on health-related quality of life (HRQOL) in breast cancer (BrCa) survivors has not been examined using a large population-based cohort...
  10. pmc Breast cancer among the oldest old: tumor characteristics, treatment choices, and survival
    Mara A Schonberg
    Beth Israel Deaconess Medical Center, 1309 Beacon, Office 202, Brookline, MA 02446, USA
    J Clin Oncol 28:2038-45. 2010
    ..Epidemiology and End Results-Medicare data set from 1992 to 2003 to examine tumor characteristics, treatments (mastectomy, breast-conserving surgery [BCS] with radiation therapy or alone, or no surgery), and outcomes of women age 80 ..
  11. ncbi The oncological safety of skin sparing mastectomy with conservation of the nipple-areola complex and autologous reconstruction: an extended follow-up study
    Bernd Gerber
    Department of Obstetrics and Gynecology, University of Rostock, Rostock, Germany
    Ann Surg 249:461-8. 2009
    To find out if skin sparing mastectomy (SSM) and nipple sparing mastectomy (NSM) with immediate autologous reconstruction as safe in oncological terms as modified radical mastectomy (MRM).
  12. ncbi Eighteen-year results in the treatment of early breast carcinoma with mastectomy versus breast conservation therapy: the National Cancer Institute Randomized Trial
    Matthew M Poggi
    Radiation Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA
    Cancer 98:697-702. 2003
    Between 1979-1987, the National Cancer Institute conducted a randomized, prospective study of mastectomy (MT) versus breast conservation therapy (BCT) in the treatment of patients with early-stage breast carcinoma...
  13. ncbi Locoregional failure 10 years after mastectomy and adjuvant chemotherapy with or without tamoxifen without irradiation: experience of the Eastern Cooperative Oncology Group
    A Recht
    Joint Center for Radiation Therapy, Harvard Medical School, and Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Clin Oncol 17:1689-700. 1999
    ..failure and how selected prognostic and treatment factors affect the risks of locoregional failure (LRF) after mastectomy in breast cancer patients with histologically involved axillary nodes treated with chemotherapy with or without ..
  14. ncbi Prevalence of and factors associated with persistent pain following breast cancer surgery
    Rune Gärtner
    Department of Breast Surgery, Rigshospitalet 2101, University of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    JAMA 302:1985-92. 2009
    ..The pathogenic mechanisms are complex and may be related to patient characteristics, surgical technique, and adjuvant therapy...
  15. ncbi Do patients and providers agree about the most important facts and goals for breast reconstruction decisions?
    Clara N Lee
    Division of Plastic and Reconstructive Surgery, University of North Carolina, Chapel Hill, NC 27599 7195, USA
    Ann Plast Surg 64:563-6. 2010
    Decisions about breast reconstruction after mastectomy are some of the most difficult decisions a breast cancer patient makes...
  16. ncbi Impact of breast surgery on survival in patients with distant metastases at initial presentation: a systematic review of the literature
    Jetske Ruiterkamp
    Department of Surgery, Jeroen Bosch Hospital, P O Box 90153, 5200 ME, s Hertogenbosch, The Netherlands
    Breast Cancer Res Treat 120:9-16. 2010
    ..In order to provide a definite answer on whether local tumor control in patients with primary metastatic disease improves survival, a randomized controlled trial comparing systemic therapy with and without breast surgery is needed...
  17. ncbi Clinicians' concerns about decision support interventions for patients facing breast cancer surgery options: understanding the challenge of implementing shared decision-making
    Lisa J M Caldon
    Department of Oncology, University of Sheffield, Sheffield, UK
    Health Expect 14:133-46. 2011
    ..in interventions that provide support for patients facing challenging decisions, such as the choice between mastectomy and breast conservation surgery for breast cancer. However, it is difficult to implement these interventions...
  18. ncbi Current trends in breast reconstruction: survey of American Society of Plastic Surgeons 2010
    Raffi Gurunluoglu
    Plastic and Reconstructive Surgery, Denver Health Medical Center, University of Colorado Health Sciences, Denver, Colorado 80204, USA
    Ann Plast Surg 70:103-10. 2013
    ..We conducted a retrospective survey of American Society of Plastic Surgeons to ascertain the current trends in breast reconstruction (BR)...
  19. pmc Are patients making high-quality decisions about breast reconstruction after mastectomy? [outcomes article]
    Clara N Lee
    Division of Plastic and Reconstructive Surgery, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599 7195, USA
    Plast Reconstr Surg 127:18-26. 2011
    Variation in rates of breast reconstruction after mastectomy has raised concerns about the quality of decisions about reconstruction...
  20. ncbi Evaluation of a local anaesthesia regimen following mastectomy
    H Talbot
    Department of Surgery, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
    Anaesthesia 59:664-7. 2004
    ..irrigation of axillary wound drains on postoperative pain during the first 24 h following a modified Patey mastectomy (mastectomy with complete axillary node clearance)...
  21. ncbi Prospective analysis of psychosocial outcomes in breast reconstruction: one-year postoperative results from the Michigan Breast Reconstruction Outcome Study
    E G Wilkins
    Section of Plastic and Reconstructive Surgery, University of Michigan Health System, Ann Arbor 48109 0340, USA
    Plast Reconstr Surg 106:1014-25; discussion 1026-7. 2000
    ..among both patients and providers have led a growing number of women to seek breast reconstruction after mastectomy. Although investigators have documented the psychological, social, emotional, and functional benefits of breast ..
  22. ncbi Quality of life at the end of primary treatment of breast cancer: first results from the moving beyond cancer randomized trial
    Patricia A Ganz
    School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
    J Natl Cancer Inst 96:376-87. 2004
    ..We investigated the baseline psychosocial status of women enrolled in a randomized trial testing two psychosocial interventions for women at the end of primary treatment...
  23. ncbi Differences in risk factors for local and distant recurrence after breast-conserving therapy or mastectomy for stage I and II breast cancer: pooled results of two large European randomized trials
    A C Voogd
    Eindhoven Cancer Registry, The Netherlands Cancer Institute, Eindhoven, The Netherlands
    J Clin Oncol 19:1688-97. 2001
    Risk factors for local and distant recurrence after breast-conserving therapy and mastectomy were compared to define guidelines for the decision making between both treatments.
  24. ncbi Randomized clinical trial investigating the use of drains and fibrin sealant following surgery for breast cancer
    P K Jain
    Department of Surgery, Scarborough General Hospital, Woodland Drive, Scarborough YO12 6QL, UK
    Br J Surg 91:54-60. 2004
    ..The aim of this study was to evaluate the effect of drains and fibrin sealant on the incidence of seroma formation...
  25. ncbi Post mastectomy adjuvant radiotherapy in breast cancer: a comparision of three hypofractionated protocols
    Abubaker Shahid
    Institute of Nuclear Medicine and Oncology INMOL, Wahdat Road, Lahore, Pakistan
    J Pak Med Assoc 59:282-7. 2009
    ..To compare three hypofractionated protocols in postmastectomy cancinoma breast in terms of local control, toxicity and work load...
  26. ncbi Recurrence after mastectomy for ductal carcinoma in situ
    Laura N Godat
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 75:592-5; discussion 595-7. 2009
    b>Mastectomy has long been a standard option for patients with ductal carcinoma in situ (DCIS). It is preferentially chosen by some women and may be suggested for individuals with recurrent, multifocal, or multicentric disease...
  27. ncbi Postmastectomy radiotherapy: clinical practice guidelines of the American Society of Clinical Oncology
    A Recht
    Beth Israel Deaconess Medical Center, Boston, MA, USA
    J Clin Oncol 19:1539-69. 2001
    ..VALIDATION: Seven outside reviewers, the American Society of Clinical Oncology (ASCO) Health Services Research Committee members, and the ASCO Board of Directors reviewed this document...
  28. ncbi The cognitive sequelae of standard-dose adjuvant chemotherapy in women with breast carcinoma: results of a prospective, randomized, longitudinal trial
    Jeffrey S Wefel
    Department of Neuro Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 100:2292-9. 2004
    ..A prospective, longitudinal trial that incorporates baseline neuropsychologic evaluations is necessary to determine to what extent cognitive dysfunction is attributable to chemotherapy in this population...
  29. ncbi Toxicity at three years with and without irradiation of the internal mammary and medial supraclavicular lymph node chain in stage I to III breast cancer (EORTC trial 22922/10925)
    Oscar Matzinger
    European Organisation for Research and Treatment of Cancer EORTC, Headquarters, Brussels, Belgium
    Acta Oncol 49:24-34. 2010
    ..We present the toxicity reported until year 3 after treatment...
  30. ncbi Complications in postmastectomy breast reconstruction: two-year results of the Michigan Breast Reconstruction Outcome Study
    Amy K Alderman
    Robert Wood Johnson Clinical Scholars Program, The University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0340, USA
    Plast Reconstr Surg 109:2265-74. 2002
    In this study, the effects of procedure type, timing, and other clinical variables on complication rates in mastectomy reconstruction were prospectively evaluated...
  31. ncbi Estrogen receptor, progesterone receptor, HER-2, and response to postmastectomy radiotherapy in high-risk breast cancer: the Danish Breast Cancer Cooperative Group
    Marianne Kyndi
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Arhus Sygehus, Noerrebrogade 44, Building 5, 2, DK 8000 Aarhus C, Denmark
    J Clin Oncol 26:1419-26. 2008
    ....
  32. ncbi Randomized multicenter trial of sentinel node biopsy versus standard axillary treatment in operable breast cancer: the ALMANAC Trial
    Robert E Mansel
    Department of Surgery, Cardiff University, Cardiff, UK
    J Natl Cancer Inst 98:599-609. 2006
    ....
  33. ncbi Neuropathic pain following breast cancer surgery: proposed classification and research update
    Beth F Jung
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 604, Rochester, NY 14642, USA
    Pain 104:1-13. 2003
  34. ncbi Complete excision of primary breast tumor improves survival of patients with metastatic breast cancer at diagnosis
    Elisabetta Rapiti
    Geneva Cancer Registry, Institute for Social and Preventive Medicine, University of Geneva
    J Clin Oncol 24:2743-9. 2006
    ..In this population-based study, we evaluate the impact of local surgery on survival of patients with metastatic breast cancer at diagnosis...
  35. ncbi Patient involvement in surgery treatment decisions for breast cancer
    Steven J Katz
    Division of General Medicine, Department of Internal Medicine, University of Michigan, 300 N Ingalls, Ste 7E12, Box 0429, Ann Arbor, MI 48109 0429, USA
    J Clin Oncol 23:5526-33. 2005
    High rates of mastectomy and marked regional variations have motivated lingering concerns about overtreatment and failure to involve women in treatment decisions...
  36. pmc Factors associated with local recurrence after skin-sparing mastectomy and immediate breast reconstruction for invasive breast cancer
    Heriberto Medina-Franco
    Department of Surgery, Section of Surgical Oncology, University of Alabama at Birmingham, USA
    Ann Surg 235:814-9. 2002
    To examine the incidence of local recurrence (LR) and factors associated with it in a population of patients who underwent skin-sparing mastectomy (SSM) and immediate reconstruction for invasive carcinoma.
  37. ncbi Boost radiotherapy in young women with ductal carcinoma in situ: a multicentre, retrospective study of the Rare Cancer Network
    Aurelius Omlin
    Department of Radiation Oncology, University of Bern, Inselspital, Bern, Switzerland
    Lancet Oncol 7:652-6. 2006
    ..Outcome data in young women with ductal carcinoma in situ (DCIS) are rare. The benefits of boost radiotherapy in this group are also unknown. We aimed to assess the effect of boost radiotherapy in young patients with DCIS...
  38. ncbi Concurrent validity of upper-extremity volume estimates: comparison of calculated volume derived from girth measurements and water displacement volume
    Joy R Karges
    Department of Physical Therapy, Division of Health Sciences, School of Medicine, University of South Dakota, 414 E Clark St, Vermillion 57069, USA
    Phys Ther 83:134-45. 2003
    ..The purpose of this study was to determine the concurrent validity of calculated volume and water displacement volume measurements...
  39. ncbi Increasing mastectomy rates among all age groups for early stage breast cancer: a 10-year study of surgical choice
    Anthony E Dragun
    Department of Radiation Oncology, James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Breast J 18:318-25. 2012
    ..surgical options for early stage breast cancer and ductal carcinoma in situ include breast conserving surgery or mastectomy. We analyzed factors that influence the receipt of mastectomy and resultant trends over time...
  40. ncbi Skin-sparing mastectomy and immediate reconstruction is an acceptable treatment option for patients with high-risk breast carcinoma
    Kevin J Downes
    Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Cancer 103:906-13. 2005
    Skin-sparing mastectomy (SSM) followed by immediate reconstruction is an effective treatment option for patients with early-stage breast carcinoma, but its use in patients with more advanced disease is controversial.
  41. ncbi Determining the oncological risk of autologous lipoaspirate grafting for post-mastectomy breast reconstruction
    Gino Rigotti
    Unità Operativa Chirurgia Plastica e Centro Ustioni, Azienda Ospedaliera di Verona, Piazzale Stefani 1, Verona, Italy
    Aesthetic Plast Surg 34:475-80. 2010
    ..windows in a homogeneous population of 137 patients who underwent fat tissue transplant after modified radical mastectomy. Median follow-up time was 7...
  42. ncbi Recurrence and mortality dynamics for breast cancer patients undergoing mastectomy according to estrogen receptor status: different mortality but similar recurrence
    Romano Demicheli
    Department of Medical Oncology, IRCCS Foundation, National Cancer Institute, Milan, Italy
    Cancer Sci 101:826-30. 2010
    ..Both recurrence and death were considered in a series of 771 patients undergoing mastectomy. ER status was available for 539 patients...
  43. ncbi Prophylactic mastectomy for the prevention of breast cancer
    Liz Lostumbo
    National Breast Cancer Coalition, 10615 Great Arbor Dr, Potomac, Maryland, USA, 20854
    Cochrane Database Syst Rev 11:CD002748. 2010
    Recent progress in understanding the genetic basis of breast cancer has increased interest in prophylactic mastectomy (PM) as a method of preventing breast cancer.
  44. ncbi Patient-physician concordance: preferences, perceptions, and factors influencing the breast cancer surgical decision
    Nancy K Janz
    Department of Health Behavior and Health Education, School of Public Health, University of Michigan, 1420 Washington Heights, Ann Arbor, MI 48109 2029, USA
    J Clin Oncol 22:3091-8. 2004
    ..The impact of demographic and psychosocial characteristics on patients' decisional role was also examined...
  45. ncbi Psychological reactions, quality of life, and body image after bilateral prophylactic mastectomy in women at high risk for breast cancer: a prospective 1-year follow-up study
    Yvonne Brandberg
    Department of Oncology Pathology, Karolinska Institutet, Radiumhemmet, Karolinska University Hospital, S 171 76, Stockholm, Sweden
    J Clin Oncol 26:3943-9. 2008
    ..of women having increased risk for breast cancer before and 6 months and 1 year after bilateral prophylactic mastectomy (BPM), and to compare preoperative expectations of the operation with postoperative reactions concerning the ..
  46. ncbi Risk factors for acute pain and its persistence following breast cancer surgery
    Jennifer Katz
    Department of Psychology, State University of New York College at Geneseo, Geneseo, NY, USA
    Pain 119:16-25. 2005
    ....
  47. ncbi Development and trends of surgical modalities for breast cancer in China: a review of 16-year data
    Ke Da Yu
    Department of Breast Surgery, Cancer Hospital Cancer Institute, Fudan University, Shanghai, 200032, People s Republic of China
    Ann Surg Oncol 14:2502-9. 2007
    ..Surgery is the most important treatment for nonmetastatic breast cancer; however, the utilization of modern surgical techniques in management of breast cancer in mainland China has not been reported...
  48. ncbi The gross anatomy of the extrathoracic course of the intercostobrachial nerve
    Marios Loukas
    Department of Anatomical Sciences, St George s University, Grenada
    Clin Anat 19:106-11. 2006
    ..e., mastectomy, axillary clearance). However, a limited number of scientific reports explore the surgical anatomy of this nerve...
  49. ncbi Computer-based learning module increases shared decision making in breast reconstruction
    Bernard T Lee
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Ann Surg Oncol 17:738-43. 2010
    ..We hypothesize that a computer-based learning module for breast reconstruction increases patient involvement in the decision-making process...
  50. ncbi Theory-based design and field-testing of an intervention to support women choosing surgery for breast cancer: BresDex
    Stephanie Sivell
    Marie Curie Palliative Care Research Group, Wales Cancer Trials Unit, School of Medicine, Cardiff University, Cardiff, UK
    Patient Educ Couns 86:179-88. 2012
    ..Design and undertake usability and field-testing evaluation of a theory-guided decision aid (BresDex) in supporting women choosing surgery for early breast cancer...
  51. ncbi Analysis of complications and patient satisfaction in pedicled transverse rectus abdominis myocutaneous and deep inferior epigastric perforator flap breast reconstruction
    Adeyiza O Momoh
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Ann Plast Surg 69:19-23. 2012
    ..5% vs. 80.7%, P = 0.0113). Understanding the differences in complications and satisfaction will help physicians and patients make informed decisions about abdominal-based autologous breast reconstruction...
  52. ncbi A single surgeon's 12-year experience with tissue expander/implant breast reconstruction: part II. An analysis of long-term complications, aesthetic outcomes, and patient satisfaction
    Peter G Cordeiro
    Plastic and Reconstructive Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 118:832-9. 2006
    ..A single surgeon's extensive experience with implant-based reconstruction provides an opportunity to evaluate these results in a uniformly treated patient population...
  53. ncbi A retrospective cohort study of post mastectomy pain syndrome
    W C Smith
    Department of Public Health, University of Aberdeen, Foresterhill, Aberdeen, UK
    Pain 83:91-5. 1999
    Post mastectomy pain syndrome is a condition which can occur following breast surgery and has until recently been regarded as uncommon. Recent reports have suggested that it may affect 20% or more of women following mastectomy...
  54. ncbi Physical and psychological morbidity after axillary lymph node dissection for breast cancer
    T F Hack
    University of Manitoba, Winnipeg, Canada
    J Clin Oncol 17:143-9. 1999
    ..Although potential negative side effects associated with ALND are known, we set out to examine whether these side effects contribute significantly to patient reports of quality of life and mental health...
  55. ncbi Breast conserving therapy versus mastectomy for stage I-II breast cancer: 20 year follow-up of the EORTC 10801 phase 3 randomised trial
    Saskia Litière
    European Organisation for Research and Treatment of Cancer, Brussels, Belgium
    Lancet Oncol 13:412-9. 2012
    The EORTC 10801 trial compared breast-conserving therapy (BCT) with modified radical mastectomy (MRM) in patients with tumours 5 cm or smaller and axillary node negative or positive disease...
  56. ncbi Increasing readiness to decide and strengthening behavioral intentions: evaluating the impact of a web-based patient decision aid for breast cancer treatment options (BresDex: www.bresdex.com)
    Stephanie Sivell
    Marie Curie Palliative Care Research Centre, Wales Cancer Trials Unit, School of Medicine, Cardiff University, Cardiff, UK
    Patient Educ Couns 88:209-17. 2012
    ..To undertake a quantitative evaluation of a theory-based, interactive online decision aid (BresDex) to support women choosing surgery for early breast cancer (Stage I and II), based on observations of its use in practice...
  57. ncbi The activity and safety of electrochemotherapy in persistent chest wall recurrence from breast cancer after mastectomy: a phase-II study
    Luca G Campana
    Sarcoma and Melanoma Unit, Veneto Region Oncology Research Institute IOV IRCCS, University of Padova, Via Gattamelata, 64, 35128 Padua, Italy
    Breast Cancer Res Treat 134:1169-78. 2012
    ..Thirty-five patients with cutaneous CWR after mastectomy who experienced progression despite re-irradiation and extensive systemic treatments were administered bleomycin-..
  58. ncbi Neuroendocrine carcinomas of the breast
    Francesca Rovera
    Department of Surgical Sciences, University of Insubria, Varese, Italy
    Int J Surg 6:S113-5. 2008
    ..They are rare lesions representing about 2-3% of all breast cancers and affecting more frequently elderly patients...
  59. ncbi Tuberculous mastitis: a disease not to be forgotten
    K E Bani-Hani
    Department of Surgery, King Abdullah University Hospital, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan
    Int J Tuberc Lung Dis 9:920-5. 2005
    ..To present our experience with tuberculous mastitis to increase the awareness of surgeons, pathologists and radiologists about this rare disease...
  60. ncbi Neuroendocrine differentiated carcinomas of the breast: a distinct entity
    Osman Zekioglu
    Ege University School of Medicine Pathology Department, Bornova, Izmir 35100, Turkey
    Breast 12:251-7. 2003
    ..Some primary carcinomas of the breast have been classified as neuroendocrine. In this paper we report on 12 cases of neuroendocrine carcinoma of the breast displaying common and uncommon histological features...
  61. ncbi Breast cancer recurrence dynamics following adjuvant CMF is consistent with tumor dormancy and mastectomy-driven acceleration of the metastatic process
    R Demicheli
    Istituto Nazionale Tumori, Milan, Italy
    Ann Oncol 16:1449-57. 2005
    ..The aim of this study was to better understand human breast cancer biology by studying how the timing of metastasis following primary resection is affected by adjuvant CMF (cyclophoshamide, methotrexate, 5-fluorouracil) chemotherapy...
  62. pmc Association between treatment with brachytherapy vs whole-breast irradiation and subsequent mastectomy, complications, and survival among older women with invasive breast cancer
    Grace L Smith
    Division of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    JAMA 307:1827-37. 2012
    ..Because results of long-term randomized trials will not be reported for years, detailed analysis of clinical outcomes in a nonrandomized setting is warranted...
  63. ncbi Are mastectomy rates really increasing in the United States?
    Elizabeth B Habermann
    University of Minnesota andVeterans Affairs Medical Center, Minneapolis, MN, USA
    J Clin Oncol 28:3437-41. 2010
    ..Institutes of Health Consensus Statement in 1990, breast-conserving surgery (BCS) became more common while mastectomy rates decreased...
  64. ncbi Body image and sexual problems in young women with breast cancer
    Pat Fobair
    Stanford University, USA
    Psychooncology 15:579-94. 2006
    ..The purpose of this study was to determine the frequency of body image and sexual problems in the first months after treatment among women diagnosed with breast cancer at age 50 or younger...
  65. ncbi Prophylactic mastectomy in high risk patients: a practice-based review of the indications. Do we follow guidelines?
    Derrick J Hoover
    Department of Surgery, Saint Barnabas Medical Center, Livingston, NJ 07039, USA
    Breast Dis 31:19-27. 2010
    ..The present study analyzed the indications and possible decision-making process leading to PM among 579 patients who underwent mastectomy.
  66. pmc A novel technique for post-mastectomy breast irradiation utilising non-coplanar intensity-modulated radiation therapy
    M Koshy
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Br J Radiol 83:874-81. 2010
    The aim of this study was to investigate if non-coplanar intensity-modulated radiation therapy (IMRT) in the post-mastectomy setting can reduce the dose to normal structures and improve target coverage...
  67. ncbi The increasing use of prophylactic mastectomy in the prevention of breast cancer
    Todd M Tuttle
    Department of Surgery, Division of Surgical Oncology, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55424, USA
    Curr Oncol Rep 12:16-21. 2010
    Selected high-risk women without breast cancer choose to undergo bilateral prophylactic mastectomy (BPM) to reduce their risk of developing the disease...
  68. ncbi Contralateral prophylactic mastectomy for unilateral breast cancer: an increasing trend at a single institution
    Natalie B Jones
    Department of Surgery, Division of Surgical Oncology, The Ohio State University, Columbus, OH, USA
    Ann Surg Oncol 16:2691-6. 2009
    An increasing trend in the use of contralateral prophylactic mastectomy (CPM) for the treatment of unilateral breast cancer has been observed nationally...
  69. ncbi Preoperative fluid and electrolyte management with oral rehydration therapy
    Hideki Taniguchi
    Department of Anesthesiology, Kanagawa Cancer Center, 1 1 2 Nakao, Asahi ku, Yokohama, 241 0815, Japan
    J Anesth 23:222-9. 2009
    ....
  70. ncbi Surveillance, control, and prevention of surgical site infections in breast cancer surgery: a 5-year experience
    Diana Vilar-Compte
    Department of Infectious Diseases, National Cancer Institute, Tlalpan, Mexico
    Am J Infect Control 37:674-9. 2009
    ..We analyzed variations in surgical site infections (SSIs) during 5 years of a prospective surveillance program and investigated possible contributors to SSIs in a cohort of patients who underwent surgery for breast cancer...
  71. ncbi Effects of mastectomy on shoulder and spinal kinematics during bilateral upper-limb movement
    Jack Crosbie
    Clinical Rehabilitation Sciences Research Group, Discipline of Physiotherapy, Faculty of Health Sciences, University of Sydney, PO Box 170, East Street, Lidcombe, New South Wales 1825, Australia
    Phys Ther 90:679-92. 2010
    ..Shoulder movement impairment is a commonly reported consequence of surgery for breast cancer...
  72. ncbi Nipple-sparing mastectomy for breast cancer and risk-reducing surgery: the Memorial Sloan-Kettering Cancer Center experience
    Paulo de Alcantara Filho
    Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 18:3117-22. 2011
    Nipple-sparing mastectomy (NSM) has been gathering increased recognition as an alternative to more traditional mastectomy approaches. Initially, questions concerning its oncologic safety limited the use of NSM...
  73. ncbi Comparing two treatment methods for post mastectomy lymphedema: complex decongestive therapy alone and in combination with intermittent pneumatic compression
    S Haghighat
    Breast Research Department, Iranian Center for Breast Cancer, Tehran, Iran
    Lymphology 43:25-33. 2010
    ..that the use of CDT alone, or in combination with IPC significantly reduced limb volume in patients with post mastectomy lymphedema. CDT alone provided better results in both treatment phases...
  74. ncbi Defining the role for autologous breast reconstruction after mastectomy: social and oncologic implications
    Warren Matthew Rozen
    Jack Brockhoff Reconstructive Plastic Surgery Research Unit, Department of Anatomy and Cell Biology, The University of Melbourne, Parkville, Victoria, Australia
    Clin Breast Cancer 8:134-42. 2008
    ..performed to evaluate the interplay between the psychosocial need for breast reconstruction in patients after mastectomy and the issues surrounding its oncologic safety...
  75. pmc Tailoring communication in consultations with women from high risk breast cancer families
    E A Lobb
    Medical Psychology Research Unit, Department of Psychological Medicine, University of Sydney, Sydney, New South Wales 2006, Australia
    Br J Cancer 87:502-8. 2002
    ..01) and breast cancer prevention with younger women (P=0.01). Prophylactic mastectomy was discussed more frequently with women with medical and allied health training (P=0...
  76. ncbi Breast cancer recurrence following postmastectomy reconstruction compared to mastectomy with no reconstruction
    Sashank Reddy
    Department of Surgery, Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Ann Plast Surg 66:466-71. 2011
    ..This study compares incidence, detection, and management of recurrent breast cancer in a large series of patients treated with mastectomy alone or with mastectomy and various forms of reconstruction.
  77. ncbi Applicability of the nipple-areola complex-sparing mastectomy: a prediction model using mammography to estimate risk of nipple-areola complex involvement in breast cancer patients
    Amy K Schecter
    North Shore Long Island Jewish Health System, Department of General Surgery, New Hyde Park, NY, USA
    Ann Plast Surg 56:498-504; discussion 504. 2006
    ..cancer patients at lowest risk for neoplastic nipple-areola complex (NAC) involvement to offer total NAC-sparing mastectomy with immediate reconstruction...
  78. ncbi Analyzing the risk of recurrence after mastectomy for DCIS: a new use for the USC/Van Nuys Prognostic Index
    Leah Kelley
    Department of Surgical Oncology, University of Southern California, Los Angeles, USA
    Ann Surg Oncol 18:459-62. 2011
    Patients with ductal carcinoma in situ (DCIS) who are treated with mastectomy seldom recur locally or with metastatic disease. When patients with DCIS recur with invasive cancer, they are upstaged and their lives are threatened...
  79. pmc Trends in mastectomy rates at the Mayo Clinic Rochester: effect of surgical year and preoperative magnetic resonance imaging
    Rajini Katipamula
    Department of Oncology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Clin Oncol 27:4082-8. 2009
    ..We sought to analyze the trends in mastectomy rates and the relationship to preoperative MRI and surgical year at Mayo Clinic, Rochester, MN.
  80. ncbi ACR appropriateness criteria on postmastectomy radiotherapy expert panel on radiation oncology-breast
    Marie E Taylor
    Washington University, Saint Louis, Missouri 63110 1032, USA
    Int J Radiat Oncol Biol Phys 73:997-1002. 2009
    This summary focuses on the role of postoperative radiation therapy in patients treated with modified radical mastectomy for invasive breast cancer, particularly in patients receiving systemic therapy.
  81. ncbi Percent positive axillary involvement predicts for the development of brain metastasis in high-risk patients with nonmetastatic breast cancer receiving post-mastectomy radiotherapy
    Ibtisam Lale Atahan
    Department of Radiation Oncology, Haceteppe University, Faculty of Medicine, Ankara, Turkey
    Breast J 14:245-9. 2008
    ..the predictive factors for brain metastasis in high-risk breast cancer patients receiving radiotherapy after mastectomy. Between January 1994 and 2002, the medical charts of nonmetastatic breast cancer patients receiving post-..
  82. ncbi The impact of skin-sparing mastectomy with immediate reconstruction in patients with Stage III breast cancer treated with neoadjuvant chemotherapy and postmastectomy radiation
    Roshan Prabhu
    Department of Radiation Oncology, Emory University, Atlanta, GA 30322, USA
    Int J Radiat Oncol Biol Phys 82:e587-93. 2012
    The safety and efficacy of skin-sparing mastectomy (SSM) with immediate reconstruction (IR) in patients with locally advanced breast cancer are unclear...
  83. ncbi A false positive for metastatic lymph nodes in the axillary region of a breast cancer patient following mastectomy
    Nobuko Fujiuchi
    Department of Breast Oncology, Saitama International Medical Center, Saitama Medical University, 1397 1 Yaname, Hidaka, Saitama, Japan
    Breast Cancer 18:141-4. 2011
    ..nodes that were diagnosed by PET/CT and ultrasonography in a 48-year-old breast cancer patient who had undergone mastectomy. The tumors, which were oval shaped and resembled lymph nodes, were detected by ultrasonography...
  84. ncbi Prognostic significance of tumor grading and staging in mammary carcinomas with neuroendocrine differentiation
    Zhen Tian
    Department of Oral Pathology, Ninth People s Hospital, Shanghai Jiao Tong University, 200011 Shanghai, China
    Hum Pathol 42:1169-77. 2011
    ..Our data suggest that routine evaluation of Ki-67 proliferation index in these unusual tumors may provide more valuable information than mitotic count alone...
  85. ncbi Dosimetry around metallic ports in tissue expanders in patients receiving postmastectomy radiation therapy: an ex vivo evaluation
    Janaki Moni
    Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA
    Med Dosim 29:49-54. 2004
    ..Strategies designed to reduce the breast reconstruction complication rate in this clinical setting will need to focus on factors other than adjusting the dosimetry around the tissue expander metallic port...
  86. ncbi Cowden syndrome and reconstructive breast surgery: case reports and review of the literature
    E Ali
    Cambridge Breast Unit, Addenbrooke s University Hospital, Cambridge, UK
    J Plast Reconstr Aesthet Surg 64:545-9. 2011
    ..We briefly describe the syndrome and review management of the risk of CS-associated malignancies. Three cases of bilateral risk-reducing mastectomy and immediate breast reconstruction are described.
  87. pmc Long-term follow-up of breast cancer survivors with post-mastectomy pain syndrome
    L Macdonald
    Department of Anaesthesia, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
    Br J Cancer 92:225-30. 2005
    Post-mastectomy pain syndrome (PMPS) is a recognised complication of breast surgery although little is known about the long-term outcome of this chronic pain condition...
  88. ncbi Use of abdominal quilting sutures for seroma prevention in TRAM flap reconstruction: a prospective, controlled trial
    Colleen McCarthy
    Division of Plastic Surgery, Department of Surgery, University of British Columbia, Vancouver, BC, Canada
    Ann Plast Surg 54:361-4. 2005
    ..Most importantly, there was no significant decrease in the incidence of seroma formation with the use of abdominal quilting sutures in this series...
  89. ncbi Randomized clinical trial on the preservation of the medial pectoral nerve following mastectomy due to breast cancer: impact on upper limb rehabilitation
    Andrea de Vasconcelos Gonçalves
    Department of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas UNICAMP, Sao Paulo, Brazil
    Sao Paulo Med J 127:117-21. 2009
    Systematic modifications to the surgical technique of mastectomy have been proposed with the objective of minimizing injuries to the pectoral nerves and their effects...
  90. ncbi Breast conservation surgery achieving>or=2 mm tumor-free margins results in decreased local-regional recurrence rates
    Charles Kunos
    Department of Radiation Oncology, University Hospitals of Cleveland, Cleveland, Ohio 44106 5000, USA
    Breast J 12:28-36. 2006
    ..Based on our findings, cosmetically acceptable tumor-free (>or=2 mm) surgical margins significantly reduce local in-breast and regional lymph node recurrences with fractionated radiation therapy, chemotherapy, and hormonal therapy...
  91. pmc Vocational rehabilitation services for patients with cancer: design of a feasibility study incorporating a pilot randomised controlled trial among women with breast cancer following surgery
    Richard G Kyle
    Cancer Care Research Centre, School of Nursing, Midwifery and Health, University of Stirling, Stirling, UK
    Trials 12:89. 2011
    ..A pilot randomised controlled trial among women with breast cancer has been designed to assess the feasibility of a larger definitive trial of VR services for people with cancer...
  92. ncbi Radiotherapy for breast cancer in patients undergoing breast reconstruction or augmentation
    Elzbieta Senkus-Konefka
    Department of Oncology and Radiotherapy, Medical University of Gdansk, Debinki 7, 80 211 Gdansk, Poland
    Cancer Treat Rev 30:671-82. 2004
    ..To minimize the risk of unfavourable outcome, the techniques and timing of both breast reconstruction and radiotherapy should be given meticulous attention...
  93. pmc Patterns and correlates of adjuvant radiotherapy receipt after lumpectomy and after mastectomy for breast cancer
    Reshma Jagsi
    Department of Radiation Oncology, University of Michigan, UHB2C490, SPC 5010, 1500 E Medical Center Dr, Ann Arbor, MI 48109 5010, USA
    J Clin Oncol 28:2396-403. 2010
    ..To use patient self-report to provide more valid estimates of whether radiotherapy (RT) is underutilized than possible with registry data, as well as to evaluate for disparities and the influence of preferences and provider interactions...
  94. ncbi Long-term survival outcomes following breast cancer surgery in Western Australia
    Katrina Spilsbury
    Western Australian Safety and Quality of Surgical Care Project, Centre for Health Services Research, School of Population Health, University of Western Australia, Crawley, Australia
    ANZ J Surg 75:625-30. 2005
    ..The aim of the present study was to investigate how hospital, social and demographic factors were associated with survival outcomes from surgically treated breast cancer for all women living in Western Australia...
  95. ncbi Adjuvant radiotherapy after mastectomy for pT1-pT2 node negative (pN0) breast cancer: is it worth the effort?
    Mia Voordeckers
    Department of Radiotherapy, Academic Hospital V U B, Laarbeeklaan 101, 1090 Jette, Brussels, Belgium
    Radiother Oncol 68:227-31. 2003
    ..Since little data on the importance of RT in this subgroup are known, we reviewed the clinical records with regard to overall survival...
  96. pmc Measuring and managing patient expectations for breast reconstruction: impact on quality of life and patient satisfaction
    Andrea L Pusic
    Division of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Expert Rev Pharmacoecon Outcomes Res 12:149-58. 2012
    ..Specifically, we consider how systematic measurement and management of patient expectations may improve patient education, shared medical decision-making and patient perception of outcomes...
  97. ncbi Antibiotic prophylaxis for preventing wound infection after breast surgery: a systematic review and metaanalysis
    Talar Tejirian
    Department of Surgery, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA 90027, USA
    J Am Coll Surg 203:729-34. 2006
  98. ncbi Decision aids and breast cancer: do they influence choice for surgery and knowledge of treatment options?
    Jennifer F Waljee
    Section of General Surgery and Section of Plastic Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI, USA
    J Clin Oncol 25:1067-73. 2007
    ..To describe the effect of decision aids on the choice for surgery and knowledge of surgical therapy among women with early-stage breast cancer...
  99. pmc Clinical practice guidelines for the care and treatment of breast cancer: 16. Locoregional post-mastectomy radiotherapy
    Pauline T Truong
    BC Cancer Agency Vancouver Island Centre
    CMAJ 170:1263-73. 2004
    To provide information and recommendations to assist women with breast cancer and their physicians in making decisions regarding the use of locoregional post-mastectomy radiotherapy (PMRT).
  100. ncbi Nipple-sparing mastectomy
    J E Rusby
    Academic Surgery, Royal Marsden NHS Foundation Trust, London, UK
    Br J Surg 97:305-16. 2010
    ..Nipple-sparing mastectomy aims to address this, but there is no consensus on its clinical application...
  101. pmc Survival analysis of cancer risk reduction strategies for BRCA1/2 mutation carriers
    Allison W Kurian
    Departments of Medicine, Health Research and Policy, and Radiology, Stanford University School of Medicine, Stanford, CA, USA
    J Clin Oncol 28:222-31. 2010
    ..We used decision analysis to simulate risk-reducing strategies in BRCA1/2 mutation carriers and to compare resulting survival probability and causes of death...

Research Grants66

  1. Cellular Mechanisms of Lymphatic Muscle Contractility
    MICHAEL JOHN DAVIS; Fiscal Year: 2012
    ..in the US currently suffer from some form of lymphedema, including a high percentage of patients recovering from mastectomy or reconstructive surgery...
  2. MBSR Symptom Cluster Trial for Breast Cancer Survivors
    Cecile A Lengacher; Fiscal Year: 2013
    ..clinical trial of 330 women with Stage 0, I, II, and III breast cancer who have undergone lumpectomy and/or mastectomy, and are within 2 years of completion of treatment with adjuvant radiation and/or chemotherapy...
  3. Virtual reality system for cancer patients'shoulder pain and psychosocial impact
    Grigore C Burdea; Fiscal Year: 2012
    ..The second aim is to evaluate the feasibility and acceptance of the prototype for women with chronic pain due to mastectomy, through an 8-week combined physical, cognitive and emotive therapy while simultaneously monitoring pain ..
  4. Wavefront Corrected Multimodal Optical Coherence and Two-Photon Microscopy for Ra
    Yuankai Kenny Tao; Fiscal Year: 2012
    ..Local recurrence following partial mastectomy is strongly correlated to the surgical margin2-4, but despite evaluation using a combination of intraoperative ..
  5. Intraoperative real time breast cancer margin assessment with nonlinear microscop
    James G Fujimoto; Fiscal Year: 2013
    ..2) Validate real time nonlinear microscopy margin assessment using simulated lumpectomies from mastectomy specimens...
  6. A new class of biodegradable synthetic biomaterial for seroma prevention
    Michael Craven; Fiscal Year: 2012
    ..vivo) into biocompatible products, and successful elimination of seroma in an accepted animal model of radical mastectomy. Phase I efforts will focus on determining the range of efficacy of MPEG-pDHA in vivo and on evaluating its ..
  7. A Decision Making Framework for Contralateral Prophylactic Mastectomy
    Patricia A Parker; Fiscal Year: 2011
    DESCRIPTION (provided by applicant): The use of contralateral prophylactic mastectomy (CPM) in the United States among patients with unilateral invasive breast cancer has increased by 150% from 1993 to 2003 with no evidence of a plateau ..
  8. Erythropoietin and Breast Cancer Stem Cells
    Frank Pajonk; Fiscal Year: 2013
    ..Limited stage BC is usually treated with mastectomy or BCS and RT. For RT, low hemoglobin (Hb) levels predict early treatment failure...
  9. A Novel Therapy for the Treatment of Chest Wall Progression of Breast Cancer
    Gary S Rogers; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: Post-mastectomy recurrence of breast cancer in the chest wall occurs in 5%-8% of cases, but it occurs more frequently in ..
  10. Effectiveness of Pre-Operative MRI in Breast Cancer Surgery and Outcomes
    Tracy Onega; Fiscal Year: 2013
    ..A major question is whether detecting additional cancer leads to more aggressive work-up and surgery (mastectomy instead of breast conserving surgery) without any concomitant benefits...
  11. Therapy for Secondary Lymphedema in Breast Cancer
    Annissa Furr; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The primary sequelae resulting from radical mastectomy and sentinel lymph node removal during the treatment of breast cancer is the development of lymphedema in related limbs...
  12. Mastectomy Reconstruction Outcome Consortium (MROC Study)
    Edwin G Wilkins; Fiscal Year: 2013
    ..provided by applicant): Despite the growing use of breast conservation as primary therapy for breast cancer, mastectomy remains a common treatment option...
  13. Luteal adjuvant oophorectomy in asian breast cancer
    RICHARD REED LOVE; Fiscal Year: 2012
    ..proposers found that benefit from adjuvant therapy was significantly greater in women undergoing simultaneous mastectomy and oophorectomy in the history-estimated luteal phases of their menstrual cycles...
  14. A Novel Optical Spectral Imaging System for Rapid Imaging of Breast Tumor Margins
    Nirmala Ramanujam; Fiscal Year: 2013
    ..Women with operable breast cancer undergo Breast Conserving Surgery (BCS), also called lumpectomy or partial mastectomy. On average between 50 to 75% of patients with breast cancer undergo BCS followed by radiation therapy...
  15. Molecular predictors of post-mastectomy breast cancer loco-regional recurrence
    Funda Meric-Bernstam; Fiscal Year: 2013
    ..e. stage T1-T3 breast cancer with 0-3 positive nodes. Patients treated with mastectomy without neoadjuvant therapy and without postoperative radiation therapy would provide the most uniform subset of ..
  16. Patient Decision Making about Breast Reconstruction after Mastectomy
    CLARA NAN HI LEE; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Breast reconstruction after mastectomy is an important treatment option for the many thousands of women who undergo mastectomy each year. Its insurance coverage is mandated by federal law...
  17. Multi-marker prognostic profile to predict invasive progression in DCIS patients
    Steven P Linke; Fiscal Year: 2012
    ..If the DCIS is large, full mastectomy is used, and the chance of recurrence is extremely low, so no further treatment is necessary...
  18. Decision-making regarding radiation therapy in breast cancer"
    Rinaa S Punglia; Fiscal Year: 2010
    ..the SEER-Medicare database, by analyzing the factors that predict for the receipt of radiation therapy after mastectomy, The selection of patients who benefit from the addition of radiation in this setting is the subject of ..
  19. Curcumin and Piperine in Breast Cancer Prevention
    Madhuri Kakarala; Fiscal Year: 2011
    ..randomized trial of oral curcumin + piperine for 28 days in women with BRCA mutations prior to prophylactic mastectomy. I will assay breast tissue and plasma for concentrations of curcumin and piperine...
  20. Novel Tree-based Statistical Methods for Cancer Risk Prediction
    Annette M Molinaro; Fiscal Year: 2013
    ..However, these women continue to be overtreated with mastectomy and radiation, at rates comparable to those with invasive cancer. The inability to discern those at low vs...
  21. Genes for human chronic pain syndromes through whole genome sequencing
    Kari Stefansson; Fiscal Year: 2013
    ..of phantom tooth pain (persistent dento-alveolar pain (PDAP)), temporomandibular disorder (TMD), and post-mastectomy pain syndrome...
  22. Statistical Methods in Cancer Control and Epidemiology
    Bradley P Carlin; Fiscal Year: 2010
    ..with breast cancer who live further from radiation treatment facilities are significantly more likely to opt for mastectomy over breast conserving surgery (``lumpectomy"), and investigating the change in estimated UV exposure levels ..
  23. INTERNET DECISION SUPPORT FOR BRCA1/BRCA2 CARRIERS
    Marc D Schwartz; Fiscal Year: 2013
    ..Management guidelines consist of intensive surveillance or consideration of risk reducing mastectomy and oophorectomy...
  24. Injectable Engineered Tissue for Cancer Reconstruction
    J Peter Rubin; Fiscal Year: 2012
    ..For patients undergoing mastectomy,the loss of one or both breasts can cause significant discomfort and psychosocial distress...
  25. Hospital and County-Level Predictors of Immediate Breast Reconstruction Post-Mast
    CATHERINE ANN RICHARDS; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Immediate breast reconstruction post-mastectomy is underutilized and there are significant racial, economic and geographic disparities...
  26. VARIABLES AFFECTING OSTOMY PATIENT OUTCOME
    Debra Jackson; Fiscal Year: 1991
    ..g., diabetes, hypertension, transplantation, mastectomy)...
  27. Managed Care Penetration and Cancer Care
    Nancy Keating; Fiscal Year: 2003
    ..care penetration and the use of treatments that are equally effective but that differ in cost for breast cancer (mastectomy versus breast conserving surgery) and prostate cancer (conservative management versus surgery or radiation ..
  28. Presurgery Hypnosis--Benefits Analysis in Breast Cancer
    Guy Montgomery; Fiscal Year: 2003
    ..o achieve these aims, 140 breast cancer patients scheduled for mastectomy will be randomly assigned to a hypnosis intervention group or an attention control group...
  29. STEROID METABOLISM AND ACTION IN CANCER
    Mortimer Levitz; Fiscal Year: 1993
    ..The tissues will be dissected promptly from breast obtained at mastectomy. This model, though subject to interpretation, eliminates the troublesome features of differential clearance and ..
  30. Louisville Breast Cancer Update
    Anees B Chagpar; Fiscal Year: 2010
    ..This year, topics to be covered will include: Indications, utility, and challenges of MRI;minimally invasive mastectomy;Innovations in reconstruction;Advances in systemic chemotherapy;Hormones in breast cancer: to replace or inhibit?..
  31. Development of a Photon Counting Detector for CT Breast Imaging
    Stephen J Glick; Fiscal Year: 2013
    ..counting x-ray CT system, and a prototype will be constructed and validated by imaging breast phantoms and fresh mastectomy specimens...
  32. MULTILEVEL COMPLIANCE MODEL OF BREAST CANCER TREATMENTS
    Mary Fennell; Fiscal Year: 1999
    ..primary treatment has been breast conserving surgery (BCS) plus radiation therapy (RT), or modified radical mastectomy. Nonetheless, geographic and hospital variation in the use of BCS, and a high portion of women, particularly ..
  33. Presurgery Hypnosis in Breast Cancer: Benefits Analysis
    Guy Montgomery; Fiscal Year: 2006
    ..goal is to establish the relative efficacy and cost of "live" and recorded presurgical hypnosis interventions in mastectomy patients...
  34. PRIMARY BREAST CANCER THERAPY GROUP
    Henry Shibata; Fiscal Year: 1980
    ..randomized clinical trial that: 1) Local therapy as indicated by Protocol B-04, a comparison of Radical Mastectomy versus Total Mastectomy versus Total Mastectomy with postoperative irradiation has no significant influence on ..
  35. Screening for Breast Cancer Using Molecular Signatures
    Timothy Yeatman; Fiscal Year: 2007
    ..signatures, within zones of histologically non-malignant breast tissue adjacent to invasive cancer derived from mastectomy specimens (n = 100). Specific Aim II...
  36. IMMEDIATE VS DELAYED RECONSTRUCTION AND BREAST CANCER SURGERY COMPLICATIONS
    Margaret A Olsen; Fiscal Year: 2013
    ..S. annually. Breast reconstruction can be performed immediately after mastectomy or delayed months to years later. 60% of the reconstructions in the U.S...
  37. A novel breast scaffold
    James Watson; Fiscal Year: 2010
    ..Breast reconstruction for mastectomy currently involves two choices, implant or autologous tissue flap...
  38. PRIMARY BREAST CANCER THERAPY GROUP (NSABP)
    Richard Margolese; Fiscal Year: 1980
    ..We have made a major contribution to Protocol 4, a comparison of Radical Mastectomy versus Total Mastectomy with Radiation vs. Total Mastectomy alone...
  39. Development of the Biobreast
    James Watson; Fiscal Year: 2013
    ..Breast reconstruction for mastectomy currently involves two choices, implant or autologous tissue flap...
  40. PRIMARY BREAST CANCER THERAPY GROUP-NSABP
    Daniel Karp; Fiscal Year: 1991
    ..38 patients per year based on the opening of NSABP breast protocols to patients who have undergone segmental mastectomy, education of surgeons regarding referral of node-negative and intraductal breast cancer patients and recent ..
  41. PRIMARY BREAST CANCER THERAPY GROUP
    Roger Poisson; Fiscal Year: 1991
    ..a trial of breast preservation (protocol 6) is underway within the NSABP to compare the value of segmental mastectomy with and without breast irradiation vs. total mastectomy...
  42. Intra-operative specimen tomosynthesis for margin assessment in breast surgery
    EMRE TOKER; Fiscal Year: 2009
    ..shown no significant difference in survival rates between women with breast cancer who are treated with radical mastectomy versus those treated with lumpectomy in conjunction with radiation therapy...
  43. Fasting Glucose in Long-Term Breast Cancer Survival
    Paola Muti; Fiscal Year: 2005
    ..who received complete resection of the neoplastic lesion (lumpectomy with margin clear of invasive cancer or mastectomy)...
  44. PRIMARY BREAST CANCER THERAPY GROUP
    Roger Poisson; Fiscal Year: 1980
    ..6, which is a protocol to compare worth of segmental mastectomy with and without breast radiation with total mastectomy plus axillary dissection...
  45. PSYCHOSOCIAL ADJUSTMENT TO CANCER--COUPLES AT RISK
    Laurel Northouse; Fiscal Year: 1993
    ..The proposed program of research, that builds on the principal investigator's initial research with mastectomy patients and their husbands, consists of three phases that extend over a five-year time period...
  46. Feasibility of CT in high risk breast cancer patients
    John Boone; Fiscal Year: 2003
    ..the potential of dedicated breast CT using computer simulation techniques coupled with CT of cadaver breasts and mastectomy specimens...
  47. LOH at BRCA1/BRCA2 Loci in Mutation Carriers as a Precursor to Breast Tumorigenes
    Mark A Brenneman; Fiscal Year: 2010
    ..2. To determine whether LOH at the BRCA loci can be similarly detected in breast tissue removed in prophylactic mastectomy from BRCA mutation carriers, in advance of any diagnosis of breast cancer. 3...
  48. Feasibility of optoacoustic tomography in backward mode
    Alexander Oraevsky; Fiscal Year: 2004
    ..Comprehensive tests in phantoms resembling properties of the breast with tumors, extensive studies in mastectomy specimen surgically excised from the breast cancer patients and pilot clinical studies on breast cancer patients ..
  49. BEHAVIORAL CONTROL OF PAIN WITH CANCER TREATMENT
    William Redd; Fiscal Year: 1980
    ..Twenty-four mastectomy patients will be asked to keep hourly records (during the day of treatment) of nausea (as measured by a visual ..
  50. ASSOCIATION OF NIPPLE ASPIRATES WITH CLINICAL FINDINGS
    Edward Sauter; Fiscal Year: 2001
    ..cancer comprise needle biopsies and procedures that encompass the entire lesion, including excisional biopsy and mastectomy. Each procedure has the risk of hematoma formation and infection...
  51. CARE, COSTS AND OUTCOMES OF LOCAL BREAST CANCER
    Jeanne Mandelblatt; Fiscal Year: 1999
    ..cost- effectiveness ratios for 3 alternative treatments for local breast cancer in the elderly: modified radical mastectomy (MRM), breast conserving surgery (BCS) with radiotherapy (RT), and BCS without RT...
  52. BREAST CANCER STAGING WITH MRI PRIOR RE-EXCISION
    Susan Orel; Fiscal Year: 2001
    ..examination, or pathologic findings will result in improved patient selection for breast conservation therapy or mastectomy. Patients who are being evaluated for possible re-excisional biopsy and breast conservation therapy will be ..
  53. Defining Signatures of Breast Cancer Cells by HRMAS MRS
    Leo Cheng; Fiscal Year: 2006
    ..but some will experience a morbid disease course and die if not promptly treated with radical intervention (mastectomy, chemo- and radiation therapies)...
  54. Isolation of human tumor cells in dormant cancer
    Jonathan Uhr; Fiscal Year: 2007
    ..the presence of circulating tumor cells (CTCs) in patients with prior breast cancer who are 7-22 years post-mastectomy and who have no evidence of disease (NED), thus very likely to be in a tumor dormancy state...
  55. ADJUVANT TAMOXIFEN THERAPY IN OLD AGE
    Rebecca Silliman; Fiscal Year: 1999
    ..Although there has been interest in variations in the use of mastectomy vs...
  56. PRIMARY BREAST CANCER THERAPY GROUP (NSABP)
    David Plotkin; Fiscal Year: 1980
    ..the worth of three-drug chemotherapy (L-PAM, 5-FU and Methotrexate) with two-drug chemotherapy segmental mastectomy with and without breast radiation with total mastectomy plus axillary dissection...
  57. PRIMARY BREAST CANCER THERAPY GROUP--NSABP
    HARVEY LERNER; Fiscal Year: 1991
    ..Protocol No. 6: A trial to compare the worth of segmental mastectomy with and without breast radiation with total mastectomy plus axillary dissection...
  58. PRIMARY BREAST CANCER THERAPY GROUP (NSABP)
    HARVEY LERNER; Fiscal Year: 1980
    ..The new protocols are: (1) No. 6: A trial to compare the worth of segmental mastectomy with and without breast radiation with total mastectomy plus axillary dissection...
  59. PRIMARY BREAST CANCER THERAPY GROUP
    CARL SUTHERLAND; Fiscal Year: 1980
    ..We project 5 patients per year by year No. 5 in Protocol No. 6, which is a trial of segmental mastectomy with and without breast irradiation and total mastectomy with axillary dissection...
  60. NURSING THERAPY--ATTENTIONAL FATIQUE IN CANCER PATIENTS
    Bernadine Cimprich; Fiscal Year: 2000
    ..with Stage I or II breast cancer, who will be treated either with breast conserving surgery plus radiation or mastectomy plus adjuvant chemotherapy, will be randomly assigned to receive usual care or an experimental intervention; a ..
  61. PRIMARY CANCER THERAPY GROUP
    JANET WOLTER; Fiscal Year: 1991
    ..These include segmental mastectomy with or without radiation therapy vs...
  62. PRIMARY BREAST CANCER THERAPY GROUP (NSABP)
    Bernard Fisher; Fiscal Year: 1980
    ..Patients (450) have been entered into protocols evaluating the relative efficacy of radical and total mastectomy with and without postoperative radiation, segmental mastectomy and a variety of protocols employing chemotherapy ..
  63. USING RESEARCH TO INFORM PATIENTS OF BREAST CANCER SURGE
    Diana Zuckerman; Fiscal Year: 2001
    Approximately 50 percent of women with early stage breast cancer undergo mastectomy, even though research indicates that lumpectomy and other types of breast-conserving surgery, when followed by radiation, are just as safe for most of ..
  64. TREATMENT OF BODY IMAGE IN A DISFIGURED POPULATION
    Leslie Heinberg; Fiscal Year: 1999
    ..g., women who have undergone mastectomy) with the goal of improving adjustment, reducing disability, and increasing compliance with medical/surgical ..
  65. CLINICAL LASER OPTOACOUSTIC SYSTEM FOR BREAST CANCER
    Alexander Oraevsky; Fiscal Year: 2002
    ..tumors, (2) the system improvement on the basis of results of initial tests, (3) evaluation of the system using mastectomy specimens, (4) modification of the system in preparations for the in vivo clinical trials and finally, (5) ..
  66. NIS Regulation in Breast Cancer
    Sissy Jhiang; Fiscal Year: 2005
    ..compound(s) to increase NIS expression and function in breast tumors enabling radionuclide to localize and ablate residual breast cancer following mastectomy, such that recurrence and metastasis of the disease can be prevented.