- Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
Edward H Romond
National Surgical Adjuvant Breast and Bowel Project, Pittsburgh, USA
N Engl J Med 353:1673-84. 2005
..We present the combined results of two trials that compared adjuvant chemotherapy with or without concurrent trastuzumab in women with surgically removed HER2-positive breast cancer...
- Ductal carcinoma in situ of the breast
Harold J Burstein
Division of Medical Oncology and the Department of Medicine, Dana Farber Cancer Institute, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
N Engl J Med 350:1430-41. 2004
- Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile
Boston University School of Medicine and Boston Medical Center, MA, USA
Br J Cancer 102:1284-93. 2010
..between breast cancer patients and usual-risk controls undergoing reduction mammoplasty (RM), and that gene expression in NlEpi from cancer-free prophylactic mastectomy (PM) samples from high-risk women would resemble HN gene expression.
- Granulomatous lobular mastitis: a complex diagnostic and therapeutic problem
Department of General Surgery, Erciyes University Medical Faculty, Kayseri, Turkey
World J Surg 30:1403-9. 2006
..The purpose of this study is to evaluate diagnostic difficulties and discuss the outcome of surgical treatment in a series of 21 patients with granulomatous lobular mastitis...
- Lung carcinoma after radiation therapy in women treated with lumpectomy or mastectomy for primary breast carcinoma
Lydia B Zablotska
Department of Epidemiology, Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Cancer 97:1404-11. 2003
Prior studies have demonstrated that women who receive adjuvant radiation therapy (RT) after mastectomy for breast carcinoma have an increased risk of a second primary lung carcinoma after 10 years, but, to the authors' knowledge, the ..
- Lymphedema and quality of life in breast cancer survivors: the Iowa Women's Health Study
Rehana L Ahmed
Department of Dermatology, University of Minnesota, Minneapolis, MN 55455 0392, USA
J Clin Oncol 26:5689-96. 2008
..The impact of lymphedema or related arm symptoms on health-related quality of life (HRQOL) in breast cancer (BrCa) survivors has not been examined using a large population-based cohort...
- Eighteen-year results in the treatment of early breast carcinoma with mastectomy versus breast conservation therapy: the National Cancer Institute Randomized Trial
Matthew M Poggi
Radiation Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA
Cancer 98:697-702. 2003
Between 1979-1987, the National Cancer Institute conducted a randomized, prospective study of mastectomy (MT) versus breast conservation therapy (BCT) in the treatment of patients with early-stage breast carcinoma...
- The oncological safety of skin sparing mastectomy with conservation of the nipple-areola complex and autologous reconstruction: an extended follow-up study
Department of Obstetrics and Gynecology, University of Rostock, Rostock, Germany
Ann Surg 249:461-8. 2009
To find out if skin sparing mastectomy (SSM) and nipple sparing mastectomy (NSM) with immediate autologous reconstruction as safe in oncological terms as modified radical mastectomy (MRM).
- Randomized clinical trial investigating the use of drains and fibrin sealant following surgery for breast cancer
P K Jain
Department of Surgery, Scarborough General Hospital, Woodland Drive, Scarborough YO12 6QL, UK
Br J Surg 91:54-60. 2004
..The aim of this study was to evaluate the effect of drains and fibrin sealant on the incidence of seroma formation...
- Breast conserving therapy versus mastectomy for stage I-II breast cancer: 20 year follow-up of the EORTC 10801 phase 3 randomised trial
European Organisation for Research and Treatment of Cancer, Brussels, Belgium
Lancet Oncol 13:412-9. 2012
The EORTC 10801 trial compared breast-conserving therapy (BCT) with modified radical mastectomy (MRM) in patients with tumours 5 cm or smaller and axillary node negative or positive disease...
- Differences in risk factors for local and distant recurrence after breast-conserving therapy or mastectomy for stage I and II breast cancer: pooled results of two large European randomized trials
A C Voogd
Eindhoven Cancer Registry, The Netherlands Cancer Institute, Eindhoven, The Netherlands
J Clin Oncol 19:1688-97. 2001
Risk factors for local and distant recurrence after breast-conserving therapy and mastectomy were compared to define guidelines for the decision making between both treatments.
- Skin-sparing mastectomy and immediate reconstruction is an acceptable treatment option for patients with high-risk breast carcinoma
Kevin J Downes
Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Cancer 103:906-13. 2005
Skin-sparing mastectomy (SSM) followed by immediate reconstruction is an effective treatment option for patients with early-stage breast carcinoma, but its use in patients with more advanced disease is controversial.
- Post mastectomy adjuvant radiotherapy in breast cancer: a comparision of three hypofractionated protocols
Institute of Nuclear Medicine and Oncology INMOL, Wahdat Road, Lahore, Pakistan
J Pak Med Assoc 59:282-7. 2009
..To compare three hypofractionated protocols in postmastectomy cancinoma breast in terms of local control, toxicity and work load...
- Quality of life at the end of primary treatment of breast cancer: first results from the moving beyond cancer randomized trial
Patricia A Ganz
School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
J Natl Cancer Inst 96:376-87. 2004
..We investigated the baseline psychosocial status of women enrolled in a randomized trial testing two psychosocial interventions for women at the end of primary treatment...
- Recurrence after mastectomy for ductal carcinoma in situ
Laura N Godat
Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
Am Surg 75:592-5; discussion 595-7. 2009
b>Mastectomy has long been a standard option for patients with ductal carcinoma in situ (DCIS). It is preferentially chosen by some women and may be suggested for individuals with recurrent, multifocal, or multicentric disease...
- Randomized multicenter trial of sentinel node biopsy versus standard axillary treatment in operable breast cancer: the ALMANAC Trial
Robert E Mansel
Department of Surgery, Cardiff University, Cardiff, UK
J Natl Cancer Inst 98:599-609. 2006
- Postmastectomy radiotherapy: clinical practice guidelines of the American Society of Clinical Oncology
Beth Israel Deaconess Medical Center, Boston, MA, USA
J Clin Oncol 19:1539-69. 2001
..VALIDATION: Seven outside reviewers, the American Society of Clinical Oncology (ASCO) Health Services Research Committee members, and the ASCO Board of Directors reviewed this document...
- Is the benefit of postmastectomy irradiation limited to patients with four or more positive nodes, as recommended in international consensus reports? A subgroup analysis of the DBCG 82 b&c randomized trials
Department of Oncology, Aarhus University Hospital, Denmark
Radiother Oncol 82:247-53. 2007
..A subgroup analysis of the DBCG 82 b&c trials was performed to evaluate the loco-regional recurrence rate and survival in relation to number of positive nodes...
- Complications in postmastectomy breast reconstruction: two-year results of the Michigan Breast Reconstruction Outcome Study
Amy K Alderman
Robert Wood Johnson Clinical Scholars Program, The University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0340, USA
Plast Reconstr Surg 109:2265-74. 2002
In this study, the effects of procedure type, timing, and other clinical variables on complication rates in mastectomy reconstruction were prospectively evaluated...
- Estrogen receptor, progesterone receptor, HER-2, and response to postmastectomy radiotherapy in high-risk breast cancer: the Danish Breast Cancer Cooperative Group
Department of Experimental Clinical Oncology, Aarhus University Hospital, Arhus Sygehus, Noerrebrogade 44, Building 5, 2, DK 8000 Aarhus C, Denmark
J Clin Oncol 26:1419-26. 2008
- Concurrent validity of upper-extremity volume estimates: comparison of calculated volume derived from girth measurements and water displacement volume
Joy R Karges
Department of Physical Therapy, Division of Health Sciences, School of Medicine, University of South Dakota, 414 E Clark St, Vermillion 57069, USA
Phys Ther 83:134-45. 2003
..The purpose of this study was to determine the concurrent validity of calculated volume and water displacement volume measurements...
- Boost radiotherapy in young women with ductal carcinoma in situ: a multicentre, retrospective study of the Rare Cancer Network
Department of Radiation Oncology, University of Bern, Inselspital, Bern, Switzerland
Lancet Oncol 7:652-6. 2006
..Outcome data in young women with ductal carcinoma in situ (DCIS) are rare. The benefits of boost radiotherapy in this group are also unknown. We aimed to assess the effect of boost radiotherapy in young patients with DCIS...
- Locoregional failure 10 years after mastectomy and adjuvant chemotherapy with or without tamoxifen without irradiation: experience of the Eastern Cooperative Oncology Group
Joint Center for Radiation Therapy, Harvard Medical School, and Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
J Clin Oncol 17:1689-700. 1999
..failure and how selected prognostic and treatment factors affect the risks of locoregional failure (LRF) after mastectomy in breast cancer patients with histologically involved axillary nodes treated with chemotherapy with or without ..
- Factors associated with local recurrence after skin-sparing mastectomy and immediate breast reconstruction for invasive breast cancer
Department of Surgery, Section of Surgical Oncology, University of Alabama at Birmingham, USA
Ann Surg 235:814-9. 2002
To examine the incidence of local recurrence (LR) and factors associated with it in a population of patients who underwent skin-sparing mastectomy (SSM) and immediate reconstruction for invasive carcinoma.
- Patient involvement in surgery treatment decisions for breast cancer
Steven J Katz
Division of General Medicine, Department of Internal Medicine, University of Michigan, 300 N Ingalls, Ste 7E12, Box 0429, Ann Arbor, MI 48109 0429, USA
J Clin Oncol 23:5526-33. 2005
High rates of mastectomy and marked regional variations have motivated lingering concerns about overtreatment and failure to involve women in treatment decisions...
- Prophylactic mastectomy in high risk patients: a practice-based review of the indications. Do we follow guidelines?
Derrick J Hoover
Department of Surgery, Saint Barnabas Medical Center, Livingston, NJ 07039, USA
Breast Dis 31:19-27. 2010
..The present study analyzed the indications and possible decision-making process leading to PM among 579 patients who underwent mastectomy.
- The increasing use of prophylactic mastectomy in the prevention of breast cancer
Todd M Tuttle
Department of Surgery, Division of Surgical Oncology, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55424, USA
Curr Oncol Rep 12:16-21. 2010
Selected high-risk women without breast cancer choose to undergo bilateral prophylactic mastectomy (BPM) to reduce their risk of developing the disease...
- Contralateral prophylactic mastectomy for unilateral breast cancer: an increasing trend at a single institution
Natalie B Jones
Department of Surgery, Division of Surgical Oncology, The Ohio State University, Columbus, OH, USA
Ann Surg Oncol 16:2691-6. 2009
An increasing trend in the use of contralateral prophylactic mastectomy (CPM) for the treatment of unilateral breast cancer has been observed nationally...
- Preoperative fluid and electrolyte management with oral rehydration therapy
Department of Anesthesiology, Kanagawa Cancer Center, 1 1 2 Nakao, Asahi ku, Yokohama, 241 0815, Japan
J Anesth 23:222-9. 2009
- A novel technique for post-mastectomy breast irradiation utilising non-coplanar intensity-modulated radiation therapy
Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Br J Radiol 83:874-81. 2010
The aim of this study was to investigate if non-coplanar intensity-modulated radiation therapy (IMRT) in the post-mastectomy setting can reduce the dose to normal structures and improve target coverage...
- Nipple-sparing mastectomy for breast cancer and risk-reducing surgery: the Memorial Sloan-Kettering Cancer Center experience
Paulo de Alcantara Filho
Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ann Surg Oncol 18:3117-22. 2011
Nipple-sparing mastectomy (NSM) has been gathering increased recognition as an alternative to more traditional mastectomy approaches. Initially, questions concerning its oncologic safety limited the use of NSM...
- Effects of mastectomy on shoulder and spinal kinematics during bilateral upper-limb movement
Clinical Rehabilitation Sciences Research Group, Discipline of Physiotherapy, Faculty of Health Sciences, University of Sydney, PO Box 170, East Street, Lidcombe, New South Wales 1825, Australia
Phys Ther 90:679-92. 2010
..Shoulder movement impairment is a commonly reported consequence of surgery for breast cancer...
- Surveillance, control, and prevention of surgical site infections in breast cancer surgery: a 5-year experience
Department of Infectious Diseases, National Cancer Institute, Tlalpan, Mexico
Am J Infect Control 37:674-9. 2009
..We analyzed variations in surgical site infections (SSIs) during 5 years of a prospective surveillance program and investigated possible contributors to SSIs in a cohort of patients who underwent surgery for breast cancer...
- Tailoring communication in consultations with women from high risk breast cancer families
E A Lobb
Medical Psychology Research Unit, Department of Psychological Medicine, University of Sydney, Sydney, New South Wales 2006, Australia
Br J Cancer 87:502-8. 2002
..01) and breast cancer prevention with younger women (P=0.01). Prophylactic mastectomy was discussed more frequently with women with medical and allied health training (P=0...
- Breast cancer among the oldest old: tumor characteristics, treatment choices, and survival
Mara A Schonberg
Beth Israel Deaconess Medical Center, 1309 Beacon, Office 202, Brookline, MA 02446, USA
J Clin Oncol 28:2038-45. 2010
..Epidemiology and End Results-Medicare data set from 1992 to 2003 to examine tumor characteristics, treatments (mastectomy, breast-conserving surgery [BCS] with radiation therapy or alone, or no surgery), and outcomes of women age 80 ..
- Breast cancer recurrence following postmastectomy reconstruction compared to mastectomy with no reconstruction
Department of Surgery, Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Ann Plast Surg 66:466-71. 2011
..This study compares incidence, detection, and management of recurrent breast cancer in a large series of patients treated with mastectomy alone or with mastectomy and various forms of reconstruction.
- Comparing two treatment methods for post mastectomy lymphedema: complex decongestive therapy alone and in combination with intermittent pneumatic compression
Breast Research Department, Iranian Center for Breast Cancer, Tehran, Iran
Lymphology 43:25-33. 2010
..that the use of CDT alone, or in combination with IPC significantly reduced limb volume in patients with post mastectomy lymphedema. CDT alone provided better results in both treatment phases...
- Defining the role for autologous breast reconstruction after mastectomy: social and oncologic implications
Warren Matthew Rozen
Jack Brockhoff Reconstructive Plastic Surgery Research Unit, Department of Anatomy and Cell Biology, The University of Melbourne, Parkville, Victoria, Australia
Clin Breast Cancer 8:134-42. 2008
..performed to evaluate the interplay between the psychosocial need for breast reconstruction in patients after mastectomy and the issues surrounding its oncologic safety...
- Trends in mastectomy rates at the Mayo Clinic Rochester: effect of surgical year and preoperative magnetic resonance imaging
Department of Oncology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
J Clin Oncol 27:4082-8. 2009
..We sought to analyze the trends in mastectomy rates and the relationship to preoperative MRI and surgical year at Mayo Clinic, Rochester, MN.
- The impact of skin-sparing mastectomy with immediate reconstruction in patients with Stage III breast cancer treated with neoadjuvant chemotherapy and postmastectomy radiation
Department of Radiation Oncology, Emory University, Atlanta, GA 30322, USA
Int J Radiat Oncol Biol Phys 82:e587-93. 2012
The safety and efficacy of skin-sparing mastectomy (SSM) with immediate reconstruction (IR) in patients with locally advanced breast cancer are unclear...
- Applicability of the nipple-areola complex-sparing mastectomy: a prediction model using mammography to estimate risk of nipple-areola complex involvement in breast cancer patients
Amy K Schecter
North Shore Long Island Jewish Health System, Department of General Surgery, New Hyde Park, NY, USA
Ann Plast Surg 56:498-504; discussion 504. 2006
..cancer patients at lowest risk for neoplastic nipple-areola complex (NAC) involvement to offer total NAC-sparing mastectomy with immediate reconstruction...
- Percent positive axillary involvement predicts for the development of brain metastasis in high-risk patients with nonmetastatic breast cancer receiving post-mastectomy radiotherapy
Ibtisam Lale Atahan
Department of Radiation Oncology, Haceteppe University, Faculty of Medicine, Ankara, Turkey
Breast J 14:245-9. 2008
..the predictive factors for brain metastasis in high-risk breast cancer patients receiving radiotherapy after mastectomy. Between January 1994 and 2002, the medical charts of nonmetastatic breast cancer patients receiving post-..
- Analyzing the risk of recurrence after mastectomy for DCIS: a new use for the USC/Van Nuys Prognostic Index
Department of Surgical Oncology, University of Southern California, Los Angeles, USA
Ann Surg Oncol 18:459-62. 2011
Patients with ductal carcinoma in situ (DCIS) who are treated with mastectomy seldom recur locally or with metastatic disease. When patients with DCIS recur with invasive cancer, they are upstaged and their lives are threatened...
- ACR appropriateness criteria on postmastectomy radiotherapy expert panel on radiation oncology-breast
Marie E Taylor
Washington University, Saint Louis, Missouri 63110 1032, USA
Int J Radiat Oncol Biol Phys 73:997-1002. 2009
This summary focuses on the role of postoperative radiation therapy in patients treated with modified radical mastectomy for invasive breast cancer, particularly in patients receiving systemic therapy.
- Prognostic significance of tumor grading and staging in mammary carcinomas with neuroendocrine differentiation
Department of Oral Pathology, Ninth People s Hospital, Shanghai Jiao Tong University, 200011 Shanghai, China
Hum Pathol 42:1169-77. 2011
..Our data suggest that routine evaluation of Ki-67 proliferation index in these unusual tumors may provide more valuable information than mitotic count alone...
- Dosimetry around metallic ports in tissue expanders in patients receiving postmastectomy radiation therapy: an ex vivo evaluation
Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA
Med Dosim 29:49-54. 2004
..Strategies designed to reduce the breast reconstruction complication rate in this clinical setting will need to focus on factors other than adjusting the dosimetry around the tissue expander metallic port...
- Cowden syndrome and reconstructive breast surgery: case reports and review of the literature
Cambridge Breast Unit, Addenbrooke s University Hospital, Cambridge, UK
J Plast Reconstr Aesthet Surg 64:545-9. 2011
..We briefly describe the syndrome and review management of the risk of CS-associated malignancies. Three cases of bilateral risk-reducing mastectomy and immediate breast reconstruction are described.
- A false positive for metastatic lymph nodes in the axillary region of a breast cancer patient following mastectomy
Department of Breast Oncology, Saitama International Medical Center, Saitama Medical University, 1397 1 Yaname, Hidaka, Saitama, Japan
Breast Cancer 18:141-4. 2011
..nodes that were diagnosed by PET/CT and ultrasonography in a 48-year-old breast cancer patient who had undergone mastectomy. The tumors, which were oval shaped and resembled lymph nodes, were detected by ultrasonography...
- Long-term follow-up of breast cancer survivors with post-mastectomy pain syndrome
Department of Anaesthesia, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
Br J Cancer 92:225-30. 2005
Post-mastectomy pain syndrome (PMPS) is a recognised complication of breast surgery although little is known about the long-term outcome of this chronic pain condition...
- Breast conservation surgery achieving>or=2 mm tumor-free margins results in decreased local-regional recurrence rates
Department of Radiation Oncology, University Hospitals of Cleveland, Cleveland, Ohio 44106 5000, USA
Breast J 12:28-36. 2006
..Based on our findings, cosmetically acceptable tumor-free (>or=2 mm) surgical margins significantly reduce local in-breast and regional lymph node recurrences with fractionated radiation therapy, chemotherapy, and hormonal therapy...
- Use of abdominal quilting sutures for seroma prevention in TRAM flap reconstruction: a prospective, controlled trial
Division of Plastic Surgery, Department of Surgery, University of British Columbia, Vancouver, BC, Canada
Ann Plast Surg 54:361-4. 2005
..Most importantly, there was no significant decrease in the incidence of seroma formation with the use of abdominal quilting sutures in this series...
- Vocational rehabilitation services for patients with cancer: design of a feasibility study incorporating a pilot randomised controlled trial among women with breast cancer following surgery
Richard G Kyle
Cancer Care Research Centre, School of Nursing, Midwifery and Health, University of Stirling, Stirling, UK
Trials 12:89. 2011
..A pilot randomised controlled trial among women with breast cancer has been designed to assess the feasibility of a larger definitive trial of VR services for people with cancer...
- Radiotherapy for breast cancer in patients undergoing breast reconstruction or augmentation
Department of Oncology and Radiotherapy, Medical University of Gdansk, Debinki 7, 80 211 Gdansk, Poland
Cancer Treat Rev 30:671-82. 2004
..To minimize the risk of unfavourable outcome, the techniques and timing of both breast reconstruction and radiotherapy should be given meticulous attention...
- Randomized clinical trial on the preservation of the medial pectoral nerve following mastectomy due to breast cancer: impact on upper limb rehabilitation
Andrea de Vasconcelos Gonçalves
Department of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas UNICAMP, Sao Paulo, Brazil
Sao Paulo Med J 127:117-21. 2009
Systematic modifications to the surgical technique of mastectomy have been proposed with the objective of minimizing injuries to the pectoral nerves and their effects...
- Adjuvant radiotherapy after mastectomy for pT1-pT2 node negative (pN0) breast cancer: is it worth the effort?
Department of Radiotherapy, Academic Hospital V U B, Laarbeeklaan 101, 1090 Jette, Brussels, Belgium
Radiother Oncol 68:227-31. 2003
..Since little data on the importance of RT in this subgroup are known, we reviewed the clinical records with regard to overall survival...
- Long-term survival outcomes following breast cancer surgery in Western Australia
Western Australian Safety and Quality of Surgical Care Project, Centre for Health Services Research, School of Population Health, University of Western Australia, Crawley, Australia
ANZ J Surg 75:625-30. 2005
..The aim of the present study was to investigate how hospital, social and demographic factors were associated with survival outcomes from surgically treated breast cancer for all women living in Western Australia...
- Decision aids and breast cancer: do they influence choice for surgery and knowledge of treatment options?
Jennifer F Waljee
Section of General Surgery and Section of Plastic Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI, USA
J Clin Oncol 25:1067-73. 2007
..To describe the effect of decision aids on the choice for surgery and knowledge of surgical therapy among women with early-stage breast cancer...
- Antibiotic prophylaxis for preventing wound infection after breast surgery: a systematic review and metaanalysis
Department of Surgery, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA 90027, USA
J Am Coll Surg 203:729-34. 2006
- Measuring and managing patient expectations for breast reconstruction: impact on quality of life and patient satisfaction
Andrea L Pusic
Division of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
Expert Rev Pharmacoecon Outcomes Res 12:149-58. 2012
..Specifically, we consider how systematic measurement and management of patient expectations may improve patient education, shared medical decision-making and patient perception of outcomes...
- Patterns and correlates of adjuvant radiotherapy receipt after lumpectomy and after mastectomy for breast cancer
Department of Radiation Oncology, University of Michigan, UHB2C490, SPC 5010, 1500 E Medical Center Dr, Ann Arbor, MI 48109 5010, USA
J Clin Oncol 28:2396-403. 2010
..To use patient self-report to provide more valid estimates of whether radiotherapy (RT) is underutilized than possible with registry data, as well as to evaluate for disparities and the influence of preferences and provider interactions...
- Clinical practice guidelines for the care and treatment of breast cancer: 16. Locoregional post-mastectomy radiotherapy
Pauline T Truong
BC Cancer Agency Vancouver Island Centre
CMAJ 170:1263-73. 2004
To provide information and recommendations to assist women with breast cancer and their physicians in making decisions regarding the use of locoregional post-mastectomy radiotherapy (PMRT).
- Survival analysis of cancer risk reduction strategies for BRCA1/2 mutation carriers
Allison W Kurian
Departments of Medicine, Health Research and Policy, and Radiology, Stanford University School of Medicine, Stanford, CA, USA
J Clin Oncol 28:222-31. 2010
..We used decision analysis to simulate risk-reducing strategies in BRCA1/2 mutation carriers and to compare resulting survival probability and causes of death...
- Ultracision reduces acute blood loss but not seroma formation after mastectomy and axillary dissection: a pilot study
Breast Unit, Mayday University Hospital, London Road, Croydon, Surrey, UK
Int J Clin Pract 60:562-4. 2006
..However, there was little difference between the two groups in terms of hospital stay, volume or duration of postoperative drainage or subsequent aspiration of seroma...
- Nipple-sparing mastectomy
J E Rusby
Academic Surgery, Royal Marsden NHS Foundation Trust, London, UK
Br J Surg 97:305-16. 2010
..Nipple-sparing mastectomy aims to address this, but there is no consensus on its clinical application...
- Prospective analysis of psychosocial outcomes in breast reconstruction: one-year postoperative results from the Michigan Breast Reconstruction Outcome Study
E G Wilkins
Section of Plastic and Reconstructive Surgery, University of Michigan Health System, Ann Arbor 48109 0340, USA
Plast Reconstr Surg 106:1014-25; discussion 1026-7. 2000
..among both patients and providers have led a growing number of women to seek breast reconstruction after mastectomy. Although investigators have documented the psychological, social, emotional, and functional benefits of breast ..
- Infectious complications following breast reconstruction with expanders and implants
Maurice Y Nahabedian
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Plast Reconstr Surg 112:467-76. 2003
..29 times higher than when no lymph nodes were removed. No significant association between implant infection and age, diabetes, tobacco use, tumor stage, timing of implant insertion, or chemotherapy was found...
- Comparison of immediate and delayed free TRAM flap breast reconstruction in patients receiving postmastectomy radiation therapy
N V Tran
Department of Plastic Surgery, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Plast Reconstr Surg 108:78-82. 2001
Tumor pathologic features and the extent of nodal involvement dictate whether radiation therapy is given after mastectomy for breast cancer...
- Risk-reduction mastectomy: clinical issues and research needs
Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA
J Natl Cancer Inst 93:1297-306. 2001
Risk-reduction mastectomy (RRM), also known as bilateral prophylactic mastectomy, is a controversial clinical option for women who are at increased risk of breast cancer...
- Repeat breast-conserving surgery for in-breast local breast carcinoma recurrence: the potential role of partial breast irradiation
Henry M Kuerer
Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 100:2269-80. 2004
b>Mastectomy is the current standard of care for in-breast local recurrence of breast carcinoma...
- Impact of IRB requirements on a multicenter survey of prophylactic mastectomy outcomes
Sarah M Greene
Group Health Cooperative Center for Health Studies, Seattle, WA 98101, USA
Ann Epidemiol 16:275-8. 2006
..This study assesses the variability in requirements among six institutional review boards (IRBs) and the resulting protocol variations for a multicenter mailed survey...
- Necrotic complications after nipple- and areola-sparing mastectomy
Andrzej L Komorowski
Department of Surgical Oncology, Maria Skłodowska Curie Memorial Institute of Oncology, Cancer Centre, Krakow, Poland
World J Surg 30:1410-3. 2006
..frequency and factors influencing necrotic complication in female patients undergoing nipple- and areola-sparing mastectomy. Nipple- and areola-sparing mastectomy has recently been shown to yield satisfactory results in a carefully ..
- The psychosocial impact of bilateral prophylactic mastectomy: prospective study using questionnaires and semistructured interviews
M B Hatcher
Cancer Research Campaign Psychosocial Oncology Group, Bland Sutton Institute, Royal Free and University College Medical School, London W1P 7PL
BMJ 322:76. 2001
OBJECTIVES: To investigate the psychosocial impact of bilateral prophylactic mastectomy for women with increased risk of breast cancer and to identify, preoperatively, risk factors for postoperative distress...
- Epithelial lesions in prophylactic mastectomy specimens from women with BRCA mutations
Noah D Kauff
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Cancer 97:1601-8. 2003
..To investigate this hypothesis, the authors compared the prevalence of histopathologic lesions in prophylactic mastectomy (PM) specimens from women with BRCA mutations and in mastectomy specimens obtained at autopsy from an age and ..
- The value of latissimus dorsi flap with implant reconstruction for total mastectomy after conservative breast cancer surgery recurrence
Division of Plastic Surgery, European Institute of Oncology, Via Ripamonti 435, 20141 Milano, Italy
Breast 20:141-4. 2011
Total mastectomy is usually indicated after breast conservative treatment cancer recurrence. Breast reconstruction in this group can be performed with many options...
- Early results of an endoscope-assisted subcutaneous mastectomy and reconstruction for breast cancer
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Surgery 131:S324-9. 2002
Subcutaneous mastectomy and reconstruction (SMR) is well established; however, most incisions are made directly on the breast, and the majority of patients care about visible scars even if they are satisfied with the reconstructed breast.
- Low locoregional recurrence rate among node-negative breast cancer patients with tumors 5 cm or larger treated by mastectomy, with or without adjuvant systemic therapy and without radiotherapy: results from five national surgical adjuvant breast and bowel
Alphonse G Taghian
National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistical Centers, Graduate School of Public Health, University of Pittsburgh, PA, USA
J Clin Oncol 24:3927-32. 2006
..In this study, we assess patterns of locoregional failure (LRF) in LN-negative patients who underwent mastectomy, either with or without adjuvant chemotherapy or hormonal therapy and without postmastectomy radiation therapy (..
- Success of neoadjuvant chemotherapy in conversion of mastectomy to breast conservation surgery
Harbor UCLA Medical Center, Torrance, California, USA
Am Surg 72:935-8. 2006
..the purpose of reducing tumor size and achieving breast conservation (BC) in individuals who initially require mastectomy. Our objective is to determine the success of NC in achieving BC in women who initially were not candidates for ..
- Minimising contralateral breast dose in post-mastectomy intensity-modulated radiotherapy by incorporating conformal electron irradiation
Hans Paul van der Laan
Department of Radiation Oncology, University Medical Center Groningen University of Groningen, Groningen, The Netherlands
Radiother Oncol 94:235-40. 2010
To assess the potential benefit of incorporating conformal electron irradiation in intensity-modulated radiotherapy (IMRT) for loco-regional post-mastectomy RT.
- Female BRCA mutation carriers with a preference for prophylactic mastectomy are more likely to participate an educational-support group and to proceed with the preferred intervention within 2 years
Karin M Landsbergen
Department of Human Genetics, Raboud University Nijmegen Medical Centre, Geert Grooteplein zuid 10, 6525 GA Nijmegen, The Netherlands
Fam Cancer 9:213-20. 2010
Women with a BRCA mutation face a complex choice between breast cancer surveillance and prophylactic mastectomy. We determined risk management preferences shortly after genetic test disclosure and mastectomy status after a median ..
- Predictors of patients' choices for breast-conserving therapy or mastectomy: a prospective study
Academic Medical Center, Department of Medical Psychology J4 401, PO Box 22 660, 1100 DD Amsterdam, The Netherlands
Br J Cancer 90:2123-30. 2004
..of patients with breast cancer, and to identify predictors of undergoing breast-conserving therapy (BCT) or mastectomy (MT). Consecutive patients with stage I/II breast cancer were eligible...
- TRAM flap for immediate post mastectomy reconstruction: comparison between pedicled and free transfer
Mahmoud M Bassiouny
The Department of Surgical Oncology, National Cancer Institute, Cairo University
J Egypt Natl Canc Inst 17:231-8. 2005
Breast reconstruction after mastectomy is primarily carried out to improve the patients' quality of life. The most commonly used autologous tissue for reconstruction is the transverse rectus abdominis musculocutaneous flap (TRAM)...
- Physical activity for the affected limb and arm lymphedema after breast cancer surgery. A prospective, randomized controlled trial with two years follow-up
Department of Breast and Endocrine Surgery, Oslo University Hospital, Ullevaal, Norway
Acta Oncol 48:1102-10. 2009
..CONCLUSION. Patients that undergo breast cancer surgery with axillary lymph node dissection should be encouraged to maintain physical activity in their daily lives without restrictions and without fear of developing ALE...
- Are breast cancer screening programmes increasing rates of mastectomy? Observational study
Unit of Epidemiology, Centre for the Study and Prevention of Cancer CSPO, Via di S Salvi 12, 50135 Florence, Italy
BMJ 325:418. 2002
- Nipple-sparing mastectomy: initial experience at the Memorial Sloan-Kettering Cancer Center and a comprehensive review of literature
Carlos A Garcia-Etienne
Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, New York NY 10021, USA
Breast J 15:440-9. 2009
Success achieved with skin-sparing mastectomy has led surgeons to reconsider the necessity of nipple-areola complex removal...
- Nipple areola skin-sparing mastectomy with immediate transverse rectus abdominis musculocutaneous flap reconstruction is an oncologically safe procedure: a single center study
Hee Jeong Kim
Department of Surgery, College of Medicine, Asan Medical Center, University of Ulsan, Seoul, Korea
Ann Surg 251:493-8. 2010
The present study evaluated the oncological safety and technical outcomes following nipple areola skin-sparing mastectomy (NASSM), skin-sparing mastectomy (SSM), and mastectomy.
- Patient satisfaction following nipple-sparing mastectomy and immediate breast reconstruction: an 8-year outcome study
Department of Plastic Surgery, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
Plast Reconstr Surg 125:818-29. 2010
Nipple-sparing mastectomy has become an accepted treatment for appropriately selected breast cancers. No reports have correlated patient satisfaction following nipple-sparing mastectomy with objective observer assessments.
- Locoregional recurrence rates and prognostic factors for failure in node-negative patients treated with mastectomy: implications for postmastectomy radiation
Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, 100 Blossom Street, Boston, MA 02114, USA
Int J Radiat Oncol Biol Phys 62:1035-9. 2005
..Survival appears improved in patients at higher risk for LRR. This study addresses whether subsets of node-negative patients with sufficiently high risk of LRR might benefit from PMRT...
- Dosimetric comparison of conventional and forward-planned intensity-modulated techniques for comprehensive locoregional irradiation of post-mastectomy left breast cancers
Matthew L Cavey
Department of Radiation Oncology, University of Texas Medical Branch, Galveston, TX 77555 0711, USA
Med Dosim 30:107-16. 2005
..The fIMRT technique demonstrated the ability to maintain the advantage of each of the other 2 techniques: reducing the dose to OARs, as with PE, and providing superior target volume coverage, as with PWT...
- Satisfaction after contralateral prophylactic mastectomy: the significance of mastectomy type, reconstructive complications, and body appearance
Marlene H Frost
Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA
J Clin Oncol 23:7849-56. 2005
Contralateral prophylactic mastectomy (CPM) is one option for reducing the risk of a second breast cancer in women with a personal and family history of breast cancer...
- Are mastectomy rates really increasing in the United States?
Elizabeth B Habermann
University of Minnesota andVeterans Affairs Medical Center, Minneapolis, MN, USA
J Clin Oncol 28:3437-41. 2010
..Institutes of Health Consensus Statement in 1990, breast-conserving surgery (BCS) became more common while mastectomy rates decreased...
- Do intraoperative analgesics influence breast cancer recurrence after mastectomy? A retrospective analysis
Department of Anesthesiology, Universite Catholique de Louvain, Louvain la Neuve, Belgium
Anesth Analg 110:1630-5. 2010
..We retrospectively reviewed our series of breast cancer surgery patients...
- Contentment with quality of life among breast cancer survivors with and without contralateral prophylactic mastectomy
Ann M Geiger
Research and Evaluation Department, Kaiser Permanente Southern California, Pasadena, USA
J Clin Oncol 24:1350-6. 2006
..To understand psychosocial outcomes after prophylactic removal of the contralateral breast in women with unilateral breast cancer...
- Preoperative dexamethasone reduces postoperative pain, nausea and vomiting following mastectomy for breast cancer
Breast Tumor Clinic Oncologic Institute of Jalisco, Health Secretary, CalleCoronel Calderon 715, Colonia El Retiro, Postal code 44280, Guadalajara, Jalisco, Mexico
BMC Cancer 10:692. 2010
..We evaluated the efficacy of preoperative dexamethasone in ameliorating postoperative nausea and vomiting (PONV), and pain after mastectomy.
- Breast cancer local recurrence after mastectomy and TRAM flap reconstruction: incidence and treatment options
Michael A Howard
Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Plast Reconstr Surg 117:1381-6. 2006
..The purpose of this study was to examine the incidence of local recurrence of breast cancer after TRAM flap breast reconstruction, evaluate treatment modalities, and determine outcomes in such cases...
- Use of tumescent mastectomy technique as a risk factor for native breast skin flap necrosis following immediate breast reconstruction
Yoon S Chun
Department of Surgery, Brigham and Women s Hospital, Faulkner Hospital, Boston, MA, USA
Am J Surg 201:160-5. 2011
Native breast skin flap necrosis is a complication that can result from ischemic injury following mastectomy and can compromise immediate breast reconstruction...
- Prevention of seroma formation after mastectomy and axillary dissection by lymph vessel ligation and dead space closure: a randomized trial
Department of Oncological Surgery, Zhongnan Hospital, Wuhan University, Hubei, China
Am J Surg 200:352-6. 2010
..We aimed to reduce the incidence of seroma formation by altering surgical technique...
- Decision making regarding prophylactic mastectomy: stability of preferences and the impact of anticipated feelings of regret
Sandra van Dijk
Department of Medical Psychology, Leiden University Medical Center, Pieter de la Court Building, Postbox 9555, 2300 RB Leiden, The Netherlands
J Clin Oncol 26:2358-63. 2008
..difficult choices to manage their breast cancer risk; one of these choices is whether to opt for prophylactic mastectomy. Few data are available about this decision-making process...
- Nipple-sparing mastectomy
Scott L Spear
Department of Plastic Surgery, Georgetown University Hospital, Washington, DC 20007, USA
Plast Reconstr Surg 123:1665-73. 2009
The debate over nipple-sparing mastectomy continues to evolve...
- Genetic counselling and the intention to undergo prophylactic mastectomy: effects of a breast cancer risk assessment
S van Dijk
Department of Medical Decision Making, Leiden University Medical Center, PO Box 9600, The Netherlands
Br J Cancer 88:1675-81. 2003
Scientific reports suggest that women at risk for familial breast cancer may benefit from prophylactic mastectomy. However, few data are available about how women decide upon this clinical option, and in particular, what role an objective ..
- Terminal duct lobular units are scarce in the nipple: implications for prophylactic nipple-sparing mastectomy: terminal duct lobular units in the nipple
Alan J Stolier
Tulane University Department of Surgery and Omega Hospital, 2525 Severn Ave, New Orleans, LA, USA
Ann Surg Oncol 15:438-42. 2008
The use of nipple-sparing mastectomy (NSM) for both breast cancer treatment and risk reduction is increasing. There is no randomized data comparing nipple-sparing mastectomy with standard mastectomy techniques...
- Sequencing chemotherapy and radiotherapy in locoregional advanced breast cancer patients after mastectomy - a retrospective analysis
Marc D Piroth
Department of Radiation Oncology, RWTH Aachen University Hospital, Aachen, Germany
BMC Cancer 8:114. 2008
..This retrospective analysis aimed to assess the role of sequencing in patients after mastectomy because of advanced locoregional disease.