dissection

Summary

Summary: The separation and isolation of tissues for surgical purposes, or for the analysis or study of their structures.

Top Publications

  1. ncbi Fiber dissection technique: lateral aspect of the brain
    U Ture
    Department of Neurosurgery, Marmara University School of Medicine, Istanbul, Turkey
    Neurosurgery 47:417-26; discussion 426-7. 2000
  2. doi Therapeutic outcomes in 1000 cases of endoscopic submucosal dissection for early gastric neoplasms: Korean ESD Study Group multicenter study
    Ii Kwun Chung
    Department of Internal Medicine, Soonchunhyang University, Cheonan, Korea
    Gastrointest Endosc 69:1228-35. 2009
  3. ncbi Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer
    Shiro Oka
    Department of Endoscopy, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Gastrointest Endosc 64:877-83. 2006
  4. ncbi Aortic dissection precedes formation of aneurysms and atherosclerosis in angiotensin II-infused, apolipoprotein E-deficient mice
    Kiran Saraff
    Division of Cardiovascular Medicine, Gill Heart Institute, Lexington, KY, USA
    Arterioscler Thromb Vasc Biol 23:1621-6. 2003
  5. ncbi Outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasms in 200 consecutive cases
    Mitsuhiro Fujishiro
    Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Clin Gastroenterol Hepatol 5:678-83; quiz 645. 2007
  6. doi Clinical outcome of endoscopic submucosal dissection versus endoscopic mucosal resection of large colorectal tumors as determined by curative resection
    Yutaka Saito
    Endoscopy Division, National Cancer Center Hospital, Chuo Ku, Tokyo, Japan
    Surg Endosc 24:343-52. 2010
  7. doi Risk factors for delayed bleeding after endoscopic submucosal dissection for gastric neoplasm
    Kazuhisa Okada
    Division of Endoscopy, Cancer Institute Hospital, 3 8 31 Ariake, Koto ku, Tokyo, 135 8550, Japan
    Surg Endosc 25:98-107. 2011
  8. ncbi Endoscopic submucosal dissection for treatment of gastric subepithelial tumors (with video)
    Andrzej Białek
    Gastroenterology Department, Pomeranian Medical University, Szczecin, Poland
    Gastrointest Endosc 75:276-86. 2012
  9. ncbi Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study
    H Isomoto
    Second Department of Internal Medicine, Nagasaki University School of Medicine, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
    Gut 58:331-6. 2009
  10. doi Routine coagulation of visible vessels may prevent delayed bleeding after endoscopic submucosal dissection--an analysis of risk factors
    K Takizawa
    Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan
    Endoscopy 40:179-83. 2008

Detail Information

Publications307 found, 100 shown here

  1. ncbi Fiber dissection technique: lateral aspect of the brain
    U Ture
    Department of Neurosurgery, Marmara University School of Medicine, Istanbul, Turkey
    Neurosurgery 47:417-26; discussion 426-7. 2000
    The fiber dissection technique involves peeling away the white matter tracts of the brain to display its three-dimensional anatomic organization. Early anatomists demonstrated many tracts and fasciculi of the brain using this technique...
  2. doi Therapeutic outcomes in 1000 cases of endoscopic submucosal dissection for early gastric neoplasms: Korean ESD Study Group multicenter study
    Ii Kwun Chung
    Department of Internal Medicine, Soonchunhyang University, Cheonan, Korea
    Gastrointest Endosc 69:1228-35. 2009
    The technique of endoscopic submucosal dissection (ESD) was introduced to be able to obtain en bloc specimens of large early GI neoplasms...
  3. ncbi Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer
    Shiro Oka
    Department of Endoscopy, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Gastrointest Endosc 64:877-83. 2006
    In EMR of early gastric cancer (EGC), en bloc resection reduces the risk of residual cancer. Endoscopic submucosal dissection (ESD) now allows en bloc resection of large EGCs.
  4. ncbi Aortic dissection precedes formation of aneurysms and atherosclerosis in angiotensin II-infused, apolipoprotein E-deficient mice
    Kiran Saraff
    Division of Cardiovascular Medicine, Gill Heart Institute, Lexington, KY, USA
    Arterioscler Thromb Vasc Biol 23:1621-6. 2003
    ....
  5. ncbi Outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasms in 200 consecutive cases
    Mitsuhiro Fujishiro
    Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Clin Gastroenterol Hepatol 5:678-83; quiz 645. 2007
    The clinical outcomes for endoscopic submucosal dissection (ESD), a novel endoluminal surgery for gastrointestinal neoplasm in the colorectum, are reported.
  6. doi Clinical outcome of endoscopic submucosal dissection versus endoscopic mucosal resection of large colorectal tumors as determined by curative resection
    Yutaka Saito
    Endoscopy Division, National Cancer Center Hospital, Chuo Ku, Tokyo, Japan
    Surg Endosc 24:343-52. 2010
    Endoscopic submucosal dissection (ESD) has recently been applied to the treatment of superficial colorectal cancer...
  7. doi Risk factors for delayed bleeding after endoscopic submucosal dissection for gastric neoplasm
    Kazuhisa Okada
    Division of Endoscopy, Cancer Institute Hospital, 3 8 31 Ariake, Koto ku, Tokyo, 135 8550, Japan
    Surg Endosc 25:98-107. 2011
    Delayed bleeding is one of the major complications of endoscopic submucosal dissection (ESD)...
  8. ncbi Endoscopic submucosal dissection for treatment of gastric subepithelial tumors (with video)
    Andrzej Białek
    Gastroenterology Department, Pomeranian Medical University, Szczecin, Poland
    Gastrointest Endosc 75:276-86. 2012
    Endoscopic submucosal dissection (ESD) is a well-accepted method for removing superficial mucosal tumors; however, there is limited data on the use of this method for removing subepithelial tumors.
  9. ncbi Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study
    H Isomoto
    Second Department of Internal Medicine, Nagasaki University School of Medicine, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
    Gut 58:331-6. 2009
    Endoscopic submucosal dissection (ESD) has the advantage over conventional endoscopic mucosa resection, permitting removal of early gastric cancer (EGC) en bloc, but long-term clinical outcomes remain unknown...
  10. doi Routine coagulation of visible vessels may prevent delayed bleeding after endoscopic submucosal dissection--an analysis of risk factors
    K Takizawa
    Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan
    Endoscopy 40:179-83. 2008
    Endoscopic submucosal dissection (ESD) has been reported to be associated with a higher complication rate than standard endoscopic mucosal resection...
  11. ncbi Clinical outcomes of EMR for gastric tumors: historical pilot evaluation between endoscopic submucosal dissection and conventional mucosal resection
    Kenichiro Watanabe
    Department of Internal Medicine, Radiology, Pathology, Saga Prefectural Hospital Koseikan, Saga Japan
    Gastrointest Endosc 63:776-82. 2006
    EMR is currently a standard treatment for mucosal gastric tumors. Endoscopic submucosal dissection (ESD) has been developed for en bloc resection.
  12. ncbi Endoscopic submucosal dissection for colorectal neoplasia: possibility of standardization
    Shinji Tanaka
    Department of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan
    Gastrointest Endosc 66:100-7. 2007
    Endoscopic submucosal dissection (ESD) has been positively applied to and gradually standardized for early stomach cancer, particularly in Japan...
  13. doi Current status and future perspectives of endoscopic submucosal dissection for colorectal tumors
    Shinji Tanaka
    Department of Endoscopy Gastroenterology, Hiroshima University Hospital, Hiroshima, Japan
    Dig Endosc 24:73-9. 2012
    Endoscopic submucosal dissection (ESD) allows for en bloc tumor resection irrespective of the size of the lesion...
  14. pmc Endoscopic submucosal dissection training with pig models in a Western country
    Adolfo Parra-Blanco
    Department of Gastroenterology, University Hospital of the Canary Islands, Ofra s n, La Laguna, 38320 Tenerife, Spain
    World J Gastroenterol 16:2895-900. 2010
    To test a strategy for endoscopic submucosal dissection (ESD) training in animal models designed to overcome the initial learning curve.
  15. doi Factors predictive of perforation during endoscopic submucosal dissection for the treatment of colorectal tumors
    E S Kim
    Department of Internal Medicine, Institute of Gastroenterology and Hepatology, Keimyung University School of Medicine, Daegu, South Korea
    Endoscopy 43:573-8. 2011
    Although perforation of the colon is known as one of the main complications of endoscopic submucosal dissection (ESD) for colorectal tumor management, factors predictive of perforation have not been fully evaluated...
  16. pmc Risk factors for bleeding after endoscopic submucosal dissection for gastric lesions
    Yosuke Tsuji
    Department of Gastroenterology, Kanto Medical Center, NTT EC, 5 9 22 Higashi Gotanda, Shinagawa ku, Tokyo 141 8625, Japan
    World J Gastroenterol 16:2913-7. 2010
    To assess risk factors for bleeding after gastric endoscopic submucosal dissection (ESD) and to develop preventive measures.
  17. ncbi Retrospective study of technical aspects and complications of endoscopic submucosal dissection for laterally spreading tumors of the colorectum
    T Toyonaga
    Department of Endoscopy, Kobe University Hospital, Kobe, Japan
    Endoscopy 42:714-22. 2010
    ..spreading tumors - non granular type (LST-NG) are more often considered candidates for endoscopic submucosal dissection (ESD) than laterally spreading tumors - granular type (LST-G), because of their higher potential for submucosal ..
  18. ncbi Do we need dissection in an integrated problem-based learning medical course? Perceptions of first- and second-year students
    Samy A Azer
    Faculty Education Unit, School of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Vic, Australia
    Surg Radiol Anat 29:173-80. 2007
    ..of the University of Melbourne has necessitated a reduction in the number of lectures and limited the use of dissection in teaching anatomy...
  19. ncbi Teaching anatomy without cadavers
    John C McLachlan
    Peninsula Medical School, University of Plymouth, C306 Portland Square, Drake Circus, Plymouth PL4 8AA, UK
    Med Educ 38:418-24. 2004
    ..Anatomy learning is generally seen as essential to medicine, and exposure to cadavers is generally seen as essential to anatomy learning around the world. Few voices dissenting from these propositions can be identified...
  20. doi Meta-analysis of endoscopic submucosal dissection versus endoscopic mucosal resection for tumors of the gastrointestinal tract
    Y Cao
    Department of Colorectal and Anal Surgery, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, People s Republic of China
    Endoscopy 41:751-7. 2009
    Endoscopic submucosal dissection (ESD) has been developed to overcome the limitations of endoscopic mucosal resection (EMR). We aimed to compare the outcomes of these two methods.
  21. doi Submucosal tumors of the esophagogastric junction originating from the muscularis propria layer: a large study of endoscopic submucosal dissection (with video)
    Quan lin Li
    Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China
    Gastrointest Endosc 75:1153-8. 2012
    ..Endoscopic submucosal dissection (ESD) has been used successfully for the removal of esophageal or gastric SMTs; however, the EGJ has been ..
  22. doi Ex vivo pig training model for esophageal endoscopic submucosal dissection (ESD) for endoscopists with experience in gastric ESD
    Shinwa Tanaka
    Division of Gastroenterology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, 7 5 1 Chu o ku, Kusunoki cho, Kobe, Hyogo 650 0017, Japan
    Surg Endosc 26:1579-86. 2012
    Esophageal endoscopic submucosal dissection (ESD) has developed in recent years because of its high rate of en bloc resection...
  23. doi Current opinions for endoscopic submucosal dissection for colorectal tumors from our experiences: indications, technical aspects and complications
    Kinichi Hotta
    Division of Endoscopy and Gastrointestinal Oncology, Shizuoka, Japan
    Dig Endosc 24:110-6. 2012
    Endoscopic submucosal dissection (ESD) was first applied in the resection of large colorectal tumors 10 years ago...
  24. doi Endoscopic submucosal dissection for treatment of rectal carcinoid tumors
    Hye Won Park
    Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Gastrointest Endosc 72:143-9. 2010
    ..Endoscopic submucosal dissection (ESD), a new method for large colorectal neoplasm resection, may overcome this problem.
  25. ncbi Xenomonitoring of Wuchereria bancrofti and Dirofilaria immitis infections in mosquitoes from American Samoa: trapping considerations and a comparison of polymerase chain reaction assays with dissection
    Eric W Chambers
    Atlanta Research and Education Foundation, Decatur, Georgia, USA
    Am J Trop Med Hyg 80:774-81. 2009
    ..Hemalum staining and dissection and polymerase chain reaction (PCR) were compared to determine the filarial infection status of Aedes (Stegomyia)..
  26. ncbi MR imaging of the temporal stem: anatomic dissection tractography of the uncinate fasciculus, inferior occipitofrontal fasciculus, and Meyer's loop of the optic radiation
    E Leon Kier
    Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06520 8042, USA
    AJNR Am J Neuroradiol 25:677-91. 2004
    ..The purpose of this investigation was to study these structures in the anterior temporal lobe and the external and extreme capsules and to correlate the dissected anatomy with the cross-sectional MR anatomy...
  27. ncbi Ultrasound-guided blocks of the ilioinguinal and iliohypogastric nerve: accuracy of a selective new technique confirmed by anatomical dissection
    U Eichenberger
    Department of Anaesthesia and General Intensive Care B, Medical University of Vienna, A 1090 Vienna, Austria
    Br J Anaesth 97:238-43. 2006
    ..This study describes a new ultrasound-guided approach to these nerves and determines its accuracy using anatomical dissection control.
  28. doi Indications for the use of endoscopic mucosal resection for early gastric cancer in Japan: a comparative study with endoscopic submucosal dissection
    S Nakamoto
    Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Chiba 2608670, Japan
    Endoscopy 41:746-50. 2009
    Endoscopic submucosal dissection (ESD) has been reported to produce excellent treatment results for early gastric cancer...
  29. ncbi Predictors of immediate bleeding during endoscopic submucosal dissection in gastric lesions
    Seong Woo Jeon
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kyungpook National University Hospital, 50 Samduk 2 Ga, Chung gu, Daegu, 700 721, South Korea
    Surg Endosc 23:1974-9. 2009
    ..resection for a gastric neoplasm, little is known about the predictors of complications of endoscopic submucosal dissection (ESD)...
  30. ncbi Endoscopic submucosal dissection allows curative resection of locally recurrent early gastric cancer after prior endoscopic mucosal resection
    Chizu Yokoi
    Department of Endoscopy, National Cancer Center Hospital, Tokyo, Japan
    Gastrointest Endosc 64:212-8. 2006
    ..EMR) to cure locally recurrent early gastric cancer (EGC) is difficult to perform because the initial EMR causes submucosal fibrosis; however, ESD allows submucosal dissection through the fibrosis and provides an en bloc specimen.
  31. ncbi Endoscopic submucosal dissection: a safe technique for colorectal tumors
    Y Tamegai
    Department of Gastroenterology, International Medical Center of Japan, Tokyo, Japan
    Endoscopy 39:418-22. 2007
    Endoscopic submucosal dissection (ESD) aims to resect large neoplastic lesions en bloc, allowing for more precise histopathological analysis...
  32. ncbi Risk factors for complications of endoscopic submucosal dissection in gastric tumors: analysis of 478 lesions
    Kotaro Mannen
    Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, 5 1 1 Nabeshima, Saga 849 8501, Japan
    J Gastroenterol 45:30-6. 2010
    Endoscopic submucosal dissection (ESD) technique has facilitated en bloc removal of widely spread lesions from the stomach. This retrospective study aimed to determine factors associated with serious complications of ESD.
  33. doi Comparison of the femtosecond laser (IntraLase) versus manual microkeratome (Moria ALTK) in dissection of the donor in endothelial keratoplasty: initial study in eye bank eyes
    Yian Jin Jones
    Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, IA, USA
    Cornea 27:88-93. 2008
    ..To determine the safety and efficacy of a femtosecond laser (IntraLase) and manual microkeratome (Moria ALTK) in creating precut endothelial keratoplasty donor tissue...
  34. doi Comparison of endoscopic submucosal dissection and endoscopic mucosal resection for large colorectal tumors
    Masahiro Tajika
    Department of Endoscopy, Aichi Cancer Center Hospital, Nagoya, Japan
    Eur J Gastroenterol Hepatol 23:1042-9. 2011
    ..Endoscopic submucosal dissection (ESD) can be performed for resection of larger tumors, but has not been studied in the colorectum because of ..
  35. doi Endoscopic submucosal dissection is an effective and safe therapy for early gastric neoplasms: a multicenter feasible study
    Takafumi Sugimoto
    Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Clin Gastroenterol 46:124-9. 2012
    The technique of endoscopic submucosal dissection (ESD) was introduced to obtain en bloc specimens of large early gastrointestinal neoplasms...
  36. doi Endoscopic submucosal dissection in large sessile lesions of the rectosigmoid: learning curve in a European center
    A Probst
    Department of Gastroenterology, Klinikum Augsburg, Stenglinstrasse 2, Augsburg, Germany
    Endoscopy 44:660-7. 2012
    Endoscopic submucosal dissection (ESD) in the colorectum is not currently a standard procedure. Few data are available from the Western world...
  37. ncbi Efficacy and safety of endoscopic submucosal dissection for gastric cancer in patients with liver cirrhosis
    K Ogura
    Department of Gastroenterology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Endoscopy 40:443-5. 2008
    Endoscopic submucosal dissection (ESD) has become a widely accepted method for treating gastrointestinal cancer. The aim of this study was to evaluate the efficacy and safety of ESD for gastric cancer in patients with liver cirrhosis...
  38. ncbi Predictive factors for esophageal stenosis after endoscopic submucosal dissection for superficial esophageal cancer
    H Mizuta
    Department of Gastroenterology and Hepatology, Kochi Medical School, Nankoku, Kochi, Japan
    Dis Esophagus 22:626-31. 2009
    Endoscopic submucosal dissection (ESD) has been utilized as an alternative treatment to endoscopic mucosal resection for superficial esophageal cancer...
  39. doi Gastric endoscopic submucosal dissection assisted by a new traction method: the clip-band technique. A feasibility study in a porcine model (with video)
    Adolfo Parra-Blanco
    Endoscopy Unit, Department of Gastroenterology, University Hospital of Canary Islands, Tenerife, Spain
    Gastrointest Endosc 74:1137-41. 2011
    Endoscopic submucosal dissection (ESD) is the standard of care for treating gastric intramucosal neoplasias in Japan. However, it is seldom performed in Western countries, mainly because it is technically very challenging...
  40. ncbi Endoscopic submucosal dissection for early gastric cancer
    Hiroyuki Ono
    Endoscopy and GI Oncology Division, Shizuoka Cancer Center Hospital, Shizuoka, Japan
    Chin J Dig Dis 6:119-21. 2005
    ..This knife can cut submucosa safely and remove a lesion completely. We named this method endoscopic submucosal dissection (ESD). Using this procedure, 96% of the tumors (471/488) were completely resected in one piece...
  41. doi Clinical risk factors for perforation during endoscopic submucosal dissection (ESD) for large-sized, nonpedunculated colorectal tumors
    Eun Jung Lee
    Department of Surgery, Daehang Hospital, Bangbae 3dong Seocho gu, Seoul 137 820, Korea
    Surg Endosc 26:1587-94. 2012
    The possible risk of colonic perforation during endoscopic submucosal dissection (ESD) for colorectal tumors is a barrier to wide application...
  42. doi Endoscopic submucosal dissection for treatment of mesopharyngeal and hypopharyngeal carcinomas
    T Iizuka
    Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan
    Endoscopy 41:113-7. 2009
    Application of the endoscopic submucosal dissection (ESD) technique, as well as elevation of the larynx in cooperation with an otolaryngologist, under general anesthesia has enabled en-block resection of early mesopharyngeal and ..
  43. doi The efficacy of endoscopic triamcinolone injection for the prevention of esophageal stricture after endoscopic submucosal dissection
    Satoru Hashimoto
    Department of Endoscopy, Niigata University Medical and Dental Hospital, Niigata, Japan
    Gastrointest Endosc 74:1389-93. 2011
    Use of endoscopic submucosal dissection (ESD) for management of widespread superficial esophageal carcinomas may be complicated by the development of severe strictures, which may require serial treatment with endoscopic balloon dilatation ..
  44. ncbi The role of three-dimensional information in health care and medical education: the implications for anatomy and dissection
    S C Marks
    Department of Cell Biology, University of Massachusetts Medical School, Worcester 01655, USA
    Clin Anat 13:448-52. 2000
    ..health care, anatomical societies need to provide answers to the following questions: Do the opportunities of dissection (visual, tactile, time, discovery, group process, mentoring) contribute to short- and long-term learning of 3-D ..
  45. doi Efficacy of novel SB knife Jr examined in a multicenter study on colorectal endoscopic submucosal dissection
    Kiyoaki Homma
    Department of Therapeutic Endoscopy, Nihonkai General Hospital, Yamagata, Japan
    Dig Endosc 24:117-20. 2012
    Secure manipulation of forceps in endoscopic submucosal dissection (ESD) for colorectal tumors is sometimes hindered by the characteristics of that organ...
  46. doi Endoscopic Doppler US for the prevention of ulcer bleeding after endoscopic submucosal dissection for early gastric cancer: a preliminary study (with video)
    Noriya Uedo
    Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
    Gastrointest Endosc 72:444-8. 2010
    After endoscopic submucosal dissection (ESD) for early gastric cancer (EGC), delayed bleeding occurs in 1.7% to 38% of cases...
  47. ncbi The feasibility of endoscopic submucosal dissection for rectal carcinoid tumors: comparison with endoscopic mucosal resection
    D S Lee
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea
    Endoscopy 42:647-51. 2010
    ..This study aimed to compare the safety and efficacy of endoscopic submucosal dissection (ESD) with endoscopic mucosal resection (EMR) for rectal carcinoid tumors.
  48. ncbi Long-term outcomes of endoscopic submucosal dissection for superficial esophageal squamous cell neoplasms
    Satoshi Ono
    Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Gastrointest Endosc 70:860-6. 2009
    The long-term outcomes of endoscopic submucosal dissection (ESD) for superficial esophageal squamous cell neoplasms (ESCNs) have not been evaluated to date.
  49. doi Endoscopic submucosal dissection for large colorectal tumors using a cross-counter technique and a novel large-diameter balloon overtube
    Koichi Okamoto
    Department of Gastroenterology and Oncology, Institute of Health Biosciences, The University of Tokushima, Tokushima, Japan
    Dig Endosc 24:96-9. 2012
    Endoscopic submucosal dissection (ESD) in early gastric cancer (EGC), which provides a higher complete resection rate than conventional endoscopic mucosal resection (EMR), has rapidly come into widespread use...
  50. ncbi Analysis of the anatomy of the Papez circuit and adjoining limbic system by fiber dissection techniques
    Abhidha Shah
    Department of Neurosurgery, Seth G S Medical College and King Edward VII Memorial Hospital, Acharya Donde Marg, Parel, Mumbai 400012, India
    J Clin Neurosci 19:289-98. 2012
    Fiber dissection techniques were used to study the limbic system, in particular the Papez circuit. The course, length and anatomical relations of the structures that make up the Papez circuit were delineated...
  51. doi Current practice with endoscopic submucosal dissection in Europe: position statement from a panel of experts
    P H Deprez
    Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Av Hippocrate 10, Brussels, Belgium
    Endoscopy 42:853-8. 2010
    Endoscopic submucosal dissection (ESD) is the gold standard technique for performing en bloc resection of large superficial tumors in the upper and lower gastrointestinal tract...
  52. ncbi Posterior cruciate ligament architecture: evaluation under microsurgical dissection
    C A Makris
    Department of Orthopaedic Surgery, University of Ioannina Medical School, Ioannina, Greece
    Arthroscopy 16:627-32. 2000
    ..PCL) and to measure the main dimensions and the femoral and tibial attachment site distances of the ligament after microsurgical dissection. We hypothesized that PCL anatomy is more complex than the 2 traditionally characterized bands.
  53. pmc Variations of the arterial pattern in the upper limb revisited: a morphological and statistical study, with a review of the literature
    M Rodriguez-Niedenführ
    Unit of Anatomy and Embryology, School of Medicine, Autonomous University of Barcelona, Spain
    J Anat 199:547-66. 2001
    ..The variable terminology previously used was unified into a homogenous and complete classification, with 12 categories covering all the previously reported variant patterns of the arm and forearm...
  54. doi Submucosal tunneling using endoscopic submucosal dissection for peritoneal access and closure in natural orifice transluminal endoscopic surgery: a porcine survival study
    F Yoshizumi
    Department of Gastroenterological Surgery, Oita University Faculty of Medicine, Yufu, Oita, Japan
    Endoscopy 41:707-11. 2009
    ..We aimed to clarify the feasibility of a submucosal tunnel technique using endoscopic submucosal dissection (ESD) for transgastric peritoneal access and subsequent closure for NOTES.
  55. ncbi Anatomical dissection as a teaching method in medical school: a review of the evidence
    Andreas Winkelmann
    Institute of Cell Biology and Neurobiology, Centre for Anatomy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Med Educ 41:15-22. 2007
    Discussions about dissection as a teaching method in gross anatomy are characterised by a lack of objective evidence.
  56. doi Usefulness and safety of SB knife Jr in endoscopic submucosal dissection for colorectal tumors
    Shiro Oka
    Department of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan
    Dig Endosc 24:90-5. 2012
    Use of a Dual knife has become commonplace for endoscopic submucosal dissection (ESD) of colorectal tumors at Hiroshima University Hosipital...
  57. doi Risk factors for immediate and delayed bleeding associated with endoscopic submucosal dissection of gastric neoplastic lesions
    Jin Seok Jang
    Department of Internal Medicine, Dong A Medical Center, University College of Medicine, Busan, Korea
    Scand J Gastroenterol 44:1370-6. 2009
    OBJECTIVE. Endoscopic submucosal dissection (ESD) of gastric neoplasia has been reported to have a higher bleeding rate than conventional endoscopic mucosal resection (EMR)...
  58. ncbi White matter fiber dissection of the optic radiations of the temporal lobe and implications for surgical approaches to the temporal horn
    Eric H Sincoff
    Cerebrovascular and Skull Base Surgery Program, Division of Neurosurgery, Saint Louis University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosurg 101:739-46. 2004
    ..and the temporal horn and superficial anatomy of the temporal lobe by using the Klingler white matter fiber dissection technique. These findings were correlated with established surgical trajectories to the temporal horn...
  59. ncbi A dissection and computer tomograph study of tarsal coalitions in 100 cadaver feet
    L B Solomon
    Department of Orthopaedics, Alice Springs Hospital, Flinders University School of Medicine, P O Box 2234, Alice Springs, NT 0871, Australia
    J Orthop Res 21:352-8. 2003
    ..There was correlation between dissection and CT in two talocalcaneal coalitions and three calcaneonavicular coalitions thus CT identifying 55...
  60. ncbi Development and implementation of a technical and didactical training program for student tutors in the dissection course
    Thomas Shiozawa
    Institute of Anatomy, Department of Experimental Embryology and Tissue Engineering, University of Tuebingen, Elfriede Aulhorn Str 8, 72076 Tuebingen, Germany
    Ann Anat 192:355-60. 2010
    ..The aim of this paper is to report a systematic approach to the development, didactic reasoning and implementation of a curriculum for training student tutors in gross anatomy...
  61. doi A new technique for gastric endoscopic submucosal dissection: peroral traction-assisted endoscopic submucosal dissection
    Won Joong Jeon
    Department of Internal Medicine, Chungbuk National University, College of Medicine and Medical Research Institute, Hungdukgu, Cheongju, Korea
    Gastrointest Endosc 69:29-33. 2009
    Compared with conventional EMR, endoscopic submucosal dissection (ESD) has a higher en bloc resection rate and complete resection rate, regardless of tumor size, in treating gastric neoplasms...
  62. ncbi Spontaneous coronary artery dissection: the clinical spectrum
    Rajiv Dhawan
    Department of Cardiology, Geisinger Medical Center, Danville, PA, USA
    Angiology 53:89-93. 2002
    Spontaneous coronary artery dissection is a rare but increasingly reported cause of myocardial ischemia and sudden death. It is more commonly seen in younger age groups and has a predilection for postpartum women...
  63. doi Endoscopic submucosal dissection for treatment of esophageal submucosal tumors originating from the muscularis propria layer
    Qiang Shi
    Endoscopy Center, Zhongshan Hospital, Fudan University, Shanghai, China
    Gastrointest Endosc 74:1194-200. 2011
    The technique of endoscopic submucosal dissection (ESD), which was developed for en bloc resection of large lesions in the stomach, has been widely accepted for the treatment of early gastric cancer...
  64. ncbi Does intrafascial dissection during nerve-sparing laparoscopic radical prostatectomy compromise cancer control?
    Mischel G Neill
    Royal Surrey County Hospital, Guildford, Surrey, UK
    BJU Int 104:1730-3. 2009
    To assess whether oncological outcomes are compromised by adopting the curtain dissection (CD) technique (high incision of the peri-prostatic fascia) during nerve-preserving radical prostatectomy (RP).
  65. doi Natural orifice translumenal endoscopic surgery (NOTES): dissection for the critical view of safety during transcolonic cholecystectomy
    Edward D Auyang
    Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 2908, USA
    Surg Endosc 23:1117-8. 2009
    ..This video shows that the critical view of safety can be attained with endoscopic dissection.
  66. doi Anatomic dissection of the inferior fronto-occipital fasciculus revisited in the lights of brain stimulation data
    Juan Martino
    Department of Neurosurgery, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain
    Cortex 46:691-9. 2010
    ..the lights of these new functional data, we dissected 14 post-mortem human hemispheres using the Klingler fiber dissection technique, to study the IFOF fibers and to identify their actual cortical terminations in the parietal, ..
  67. doi Safety of extended endoscopic mucosal resection and endoscopic submucosal dissection following the Japanese Gastric Cancer Association treatment guidelines
    Y S Jee
    Department of Surgery, Seoul National University Bundang Hospital, Seoul, Korea
    Br J Surg 96:1157-61. 2009
    Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are widely performed. Indications for these procedures have been extended in Korea and Japan. The aim was to evaluate whether these extended indications are safe...
  68. doi A second-look endoscopy after endoscopic submucosal dissection for gastric epithelial neoplasm may be unnecessary: a retrospective analysis of postendoscopic submucosal dissection bleeding
    Osamu Goto
    Department of Gastroenterology, The University of Tokyo, Tokyo, Japan
    Gastrointest Endosc 71:241-8. 2010
    Endoscopic submucosal dissection (ESD) is one of the curative endoluminal surgical procedures for gastric epithelial neoplasms. There has been little research on bleeding after gastric ESD.
  69. ncbi Novel biodegradable stents for benign esophageal strictures following endoscopic submucosal dissection
    Yasuharu Saito
    Department of Endoscopic Medicine, Shiga University of Medical Science, Seta Tukinowa, Otsu 520 2192, Japan
    Dig Dis Sci 53:330-3. 2008
    ..acid (PLLA) esophageal stent in two patients with benign esophageal stenosis after endoscopic submucosal dissection (ESD)...
  70. doi Sonographic visualization and ultrasound-guided blockade of the greater occipital nerve: a comparison of two selective techniques confirmed by anatomical dissection
    M Greher
    Department of Anaesthesiology, Perioperative Intensive Care and Pain Therapy, Herz Jesu Hospital, A 1030 Vienna, Austria
    Br J Anaesth 104:637-42. 2010
    ..Our cadaver study compares the sonographic visibility of the nerve and the accuracy and specificity of ultrasound-guided injections at two different sites...
  71. doi Single-incision laparoscopic cholecystectomy: initial experience with critical view of safety dissection and routine intraoperative cholangiography
    Arthur Rawlings
    Department of Surgery and Institute for Minimally Invasive Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Am Coll Surg 211:1-7. 2010
    ..is more widely used, it is important to maintain well-established practices of the critical view of safety (CVS) dissection and intraoperative cholangiography (IOC)...
  72. ncbi Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes
    Wesley G Beamer
    The Jackson Laboratory, Bar Harbor, Maine, USA
    J Bone Miner Res 22:1187-96. 2007
    ..The homologous relationship between distal mouse Chr 1 and human 1q21-24 offers the possibility of finding common regulatory genes for cortical and trabecular bone...
  73. doi Endoscopic mucosal resection and endoscopic submucosal dissection
    Sergey V Kantsevoy
    Gastrointest Endosc 68:11-8. 2008
  74. doi Prospective clinical trial of magnetic-anchor-guided endoscopic submucosal dissection for large early gastric cancer (with videos)
    Takuji Gotoda
    Endoscopy Division, National Cancer Center Hospital, Chuo Ku, Tokyo, Japan
    Gastrointest Endosc 69:10-5. 2009
    The treatment of early gastric cancer (EGC) by endoscopic submucosal dissection (ESD) has been rapidly gaining popularity in Japan. However, the procedure needs a high quality of skill...
  75. ncbi A prospective randomized trial comparing harmonic scalpel versus electrocautery for pectoralis major myocutaneous flap dissection
    Suryanarayana Deo
    Department of Surgical Oncology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
    Plast Reconstr Surg 115:1006-9. 2005
    ..The reported morbidity rate using conventional techniques of flap dissection varies from 16 to 63 percent...
  76. ncbi Endoscopic submucosal dissection for treatment of early stage hypopharyngeal carcinoma
    Yuichi Shimizu
    Division of Endoscopy and Department of Otolaryngology, Hokkaido University Hospital, Sapporo, Japan
    Gastrointest Endosc 64:255-9; discussion 260-2. 2006
    ..Early detection of hypopharyngeal carcinoma is increasingly possible and patients with such early lesions can be treated with endoscopic resection...
  77. ncbi Microsurgical anatomy and quantitative analysis of the transtemporal-transchoroidal fissure approach to the ambient cistern
    Rungsak Siwanuwatn
    Division of Neurological Surgery, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
    Neurosurgery 57:228-35; discussion 228-35. 2005
    ..Surgical approaches to ambient cistern lesions are complex. We investigated the microanatomy of the transtemporal-transchoroidal fissure approach to the ambient cistern with emphasis on exposure of the posterior cerebral artery...
  78. ncbi Tension and energy-free robotic-assisted laparoscopic radical prostatectomy with interfascial dissection of the neurovascular bundles
    Agostino Mattei
    Service d Urologie, Clinique Saint Augustin, Bordeaux, France
    Eur Urol 52:687-94. 2007
    ..and early functional results after robotic-assisted laparoscopic radical prostatectomy (RALP) with a new lateral approach for the interfascial dissection of the neurovascular bundles without tension and any use of electrocautery.
  79. doi Variation of the vastus medialis obliquus insertion and its relevance to minimally invasive total knee arthroplasty
    Graeme Holt
    Department of Orthopaedic Surgery, Hairmyres Hospital, East Kilbride, United Kingdom
    J Arthroplasty 23:600-4. 2008
    ..Laterality and sex had no effect upon the level of insertion. The VMO has a variable and frequently distal insertion that may preclude a true quadriceps-sparing approach during minimally invasive knee arthroplasty...
  80. pmc Anatomic basis of sharp pelvic dissection for curative resection of rectal cancer
    Nam Kyu Kim
    Department of Surgery, Division of Colorectal Surgery, Yonsei University College of Medicine, 134 Shinchon dong, Seodaemun gu, Seoul 120 752, Korea
    Yonsei Med J 46:737-49. 2005
    ..With the emergence of total mesorectal excision in the field of rectal cancer surgery, anatomical sharp pelvic dissection has been emphasized to achieve these therapeutic goals...
  81. ncbi Minimally invasive far lateral microendoscopic discectomy for extraforaminal disc herniation at the lumbosacral junction: cadaveric dissection and technical case report
    John E O'Toole
    Department of Neurosurgery, Rush University Medical Center, 1725 W Harrison Street, Chicago, IL 60612, USA
    Spine J 7:414-21. 2007
    ..Reports specifically describing minimally invasive surgical approaches to lumbosacral ELDHs are lacking...
  82. ncbi Comparison of harmonic scalpel and high-frequency electrocautery in radial artery harvesting
    B Erkut
    Department of Cardiovascular Surgery, Medical Faculty, Ataturk University, Erzurum, Turkey
    J Cardiovasc Surg (Torino) 49:371-9. 2008
    ..We evaluated the effects of the radial artery on the functional outcomes and endothelium when the harvest was made either by harmonic scalpel or by high-frequency electrocautery...
  83. ncbi Pancreatic contamination of mesenteric adipose tissue samples can be avoided by adjusted dissection procedures
    Robert Caesar
    Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway
    J Lipid Res 49:1588-94. 2008
    ..Because the boundary between pancreas and mesenteric fat cannot be easily distinguished during dissection, we conclude that investigators should routinely exclude the proximal section of the mesenteric adipose tissue ..
  84. pmc A prospective randomized trial of either famotidine or pantoprazole for the prevention of bleeding after endoscopic submucosal dissection
    Hye Kyong Jeong
    Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea
    J Korean Med Sci 22:1055-9. 2007
    Endoscopic submucosal dissection (ESD) has been reported to have a higher bleeding rate than conventional methods...
  85. doi Diffusion tensor tractography of the temporal stem on the inferior limiting sulcus
    Feng Wang
    Department of Neurosurgery, Qilu Hospital of the Shandong University, Jinan, Shandong, China
    J Neurosurg 108:775-81. 2008
    ....
  86. doi Degree of healing and healing-associated factors of endoscopic submucosal dissection-induced ulcers after pantoprazole therapy for 4 weeks
    Tae Hoon Oh
    Department of Internal Medicine, Inje University College of Medicine, Sanggye Paik Hospital, Seoul, South Korea
    Dig Dis Sci 54:1494-9. 2009
    There is no consensus regarding the degree of healing of endoscopic submucosal dissection (ESD)-induced ulcers and the optimal duration of proton pump inhibitor (PPI) treatment.
  87. ncbi Satisfaction with bispectral index monitoring of propofol-mediated sedation during endoscopic submucosal dissection: a prospective, randomized study
    A Imagawa
    Tsuyama Central Hospital, Department of Gastroenterology, Okayama, Japan
    Endoscopy 40:905-9. 2008
    Endoscopic submucosal dissection (ESD) is one of the most complex and lengthy endoscopic procedures, so deep sedation during ESD is indispensable...
  88. ncbi Effect of perifoveal tissue dissection in the management of acute idiopathic full-thickness macular holes
    R R Margherio
    Associated Retinal Consultants and William Beaumont Hospital, Royal Oak, Mich, USA
    Arch Ophthalmol 118:495-8. 2000
    To evaluate the efficacy of perifoveal tissue dissection (PTD) on patients undergoing pars plana vitrectomy for idiopathic macular holes of less than 1-year's duration.
  89. doi Endoscopic submucosal dissection in the colorectum: present status and future prospects
    Toshio Uraoka
    Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
    Dig Endosc 21:S13-6. 2009
    Endoscopic submucosal dissection (ESD) can successfully resect early stage gastrointestinal tumors, but colorectal ESDs are not widely performed, even by Japanese endoscopists, because of several negative factors...
  90. doi Endoscopic submucosal dissection in the upper gastrointestinal tract: present and future view of Europe
    Horst Neuhaus
    Evangelisches Krankenhaus, Dusseldorf, Germany
    Dig Endosc 21:S4-6. 2009
    ..In contrast endoscopic submucosal dissection (ESD) is infrequently performed for several reasons...
  91. doi Endoscopic submucosal dissection for esophageal squamous cell neoplasms
    Mitsuhiro Fujishiro
    Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    Dig Endosc 21:109-15. 2009
    Endoscopic submucosal dissection (ESD) has gradually gained acceptance as one of the standard treatments for early esophageal cancer, as well as for early gastric cancer in Japan, but standardization of the knowledge is still incomplete...
  92. ncbi Endoscopic submucosal dissection for early gastric cancer performed by supervised residents: assessment of feasibility and learning curve
    Shunsuke Yamamoto
    Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537 8511, Japan
    Endoscopy 41:923-8. 2009
    Endoscopic submucosal dissection (ESD) is feasible as a treatment for early gastric cancer (EGC) when it is performed by an experienced endoscopist...
  93. ncbi An innovative technique for endoscopic submucosal dissection of early gastric cancer using a new spring device
    N Sakurazawa
    Department of Surgery, Nippon Medical School, Tokyo 113 8603, Japan
    Endoscopy 41:929-33. 2009
    In recent years, endoscopic submucosal dissection (ESD) has been applied for the treatment of gastric tumors, and the en-bloc resection rate of early gastric cancer has greatly improved...
  94. ncbi Progressive surgical dissection for tendon transposition affects length-force characteristics of rat flexor carpi ulnaris muscle
    Mark J C Smeulders
    J Orthop Res 20:863-8. 2002
    ..To test the hypothesis that surgical dissection of a muscle will affect its length-force characteristics, a study was undertaken in adult male Wistar rats...
  95. doi Difficulties and outcomes in starting endoscopic submucosal dissection
    Anthony Yuen Bun Teoh
    Division of Upper Gastrointestinal Surgery, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong SAR, China
    Surg Endosc 24:1049-54. 2010
    Endoscopic submucosal dissection (ESD) is a technically demanding procedure associated with a higher risk of complications. This study aimed to assess the difficulties and outcomes experienced by endoscopists beginning to perform ESD.
  96. ncbi Spontaneous coronary artery dissection--a case report and review of the literature
    Hassan A Mohamed
    Department of Medicine, Regina General Hospital, SK, Canada
    Angiology 53:205-11. 2002
    Spontaneous coronary artery dissection remains an extremely rare cause of myocardial ischemia and infarction. The clinical picture of spontaneous coronary dissection is often sudden cardiac death or fatal myocardial infarction...
  97. pmc Endoscopic submucosal dissection in dogs in a World Gastroenterology Organisation training center
    Miguel A Tanimoto
    Department of Gastroenterology and World Gastroenterology Organisation Training Center, National Institute of Medical Sciences and Nutrition Salvador Zubiran, Vasco de Quiroga 15, Colonia Seccion XVI, Delegacion Tlalpan C P, Mexico City 14000, Mexico
    World J Gastroenterol 16:1759-64. 2010
    To evaluate if canine models are appropriate for teaching endoscopy fellows the techniques of endoscopic submucosal dissection (ESD).
  98. pmc Dissection by ultrasonic energy versus monopolar electrosurgical energy in laparoscopic cholecystectomy
    Walid Sasi
    Department of General Surgery, St George s Hospital and Medical School, University of London, UK
    JSLS 14:23-34. 2010
    ..Electrocautery remains the main energy form used during laparoscopic dissection. However, due to its risks, search is continuous for safer and more efficient forms of energy...
  99. pmc Laryngeal recurrent nerve injury in surgery for benign thyroid diseases: effect of nerve dissection and impact of individual surgeon in more than 27,000 nerves at risk
    Michael Hermann
    Department of Surgery, Kaiserin Elisabeth Spital, University of Vienna, Vienna, Austria
    Ann Surg 235:261-8. 2002
    To evaluate the effect of recurrent nerve dissection on the incidence of recurrent laryngeal nerve injury (RLNI) and to analyze the performance of individual surgeons.
  100. doi Endoscopic submucosal dissection in gastric neoplasia - experience from a European center
    A Probst
    III Department of Gastroenterology, Klinikum Augsburg, Augsburg, Germany
    Endoscopy 42:1037-44. 2010
    Endoscopic submucosal dissection (ESD) is a promising technique for the resection of early gastric neoplasia. There are only a few data from the Western world to date.
  101. doi Learning curve for endoscopic submucosal dissection of large colorectal tumors
    Kinichi Hotta
    Department of Gastroenterology, Saku Central Hospital, Saku, Nagano, Japan
    Dig Endosc 22:302-6. 2010
    No studies have previously described the learning curve for colonic endoscopic submucosal dissection (ESD)...

Research Grants91

  1. Bioengineering Core for Cellular and Tissue Models
    Andrew McCulloch; Fiscal Year: 2009
    ..are mounted in the cardiac tissue culture chamber, containing the same Hepes buffered solution used for the dissection. Muscles are mounted between a basket attached to a force transducer and actuator controlled micromanipulator, ..
  2. Massively Parallel Brain Imaging
    MARK SCHNITZER; Fiscal Year: 2009
    ..Applications of our technology will also be plentiful in other model organisms such as nematodes and zebrafish, profoundly impacting multiple areas of biomedicine. ..
  3. A Network Biology Approach to Antibiotic Action and Bacterial Defense Mechanisms
    James Collins; Fiscal Year: 2009
    ..This project may thus enable the development of novel classes of antibiotics that account for and utilize the complex regulatory properties of genetic networks. ..
  4. Prevention of Acute Lung Injury by IL-6 activated STAT3
    Ana Moran; Fiscal Year: 2010
    ..Q-RT-PCR using amplified (a)RNA from laser capture micro-dissection (LCM)-isolated AECs and non(n)-AEC cells from sham, HS and HS/I rat lungs revealed: 1) that the assignment of ..
  5. Deregulated Wnt Signaling in Prostate Cancer
    Scott Houghtaling; Fiscal Year: 2009
    ..hope to develop skills in transgene construction, animal husbandry, and phenotypic analysis through observation, dissection, tissue fixation, histology preparation and microscopic evaluation...
  6. DISSECTION OF THE FUNCTIONS OF HERPES SIMPLEX VIRUS ICPO
    Bernard Roizman; Fiscal Year: 2009
    ....
  7. A GENETIC ANALYSIS OF TASTE IN DROSOPHILA
    Beth Gordesky Gold; Fiscal Year: 2007
    ..Drosophila are a highly successful model for the molecular dissection of behavior, and ingestive behavior promises to be very applicable to this analysis...
  8. Novel Biomarkers in Aortic Aneurysms and Acute Aortic Dissection
    Jennifer Van Eyk; Fiscal Year: 2009
    ..Change Topic, 06- HL-101 "Developing technologies for assessment of aortic aneurysms prone to rupture or dissection". Aortic dissection describes a tear in the wall of the main vessel in the body, the aorta...
  9. Novel Biomarkers in Aortic Aneurysms and Acute Aortic Dissection
    JENNIFER E contact VAN EYK; Fiscal Year: 2010
    ..Change Topic, 06- HL-101 "Developing technologies for assessment of aortic aneurysms prone to rupture or dissection". Aortic dissection describes a tear in the wall of the main vessel in the body, the aorta...
  10. Complement in Cell Proliferation and Injury-Therapeutic Interventions
    John D Lambris; Fiscal Year: 2010
    ..Each laboratory involved has developed well-defined model systems that will allow the dissection of the critical components and mechanisms by which the complement system participates in cell survival or ..
  11. Complement in Cell Proliferation and Injury-Therapeutic Interventions
    John Lambris; Fiscal Year: 2009
    ..Each laboratory involved has developed well-defined model systems that will allow the dissection of the critical components and mechanisms by which the complement system participates in cell survival or ..
  12. Complement in Cell Proliferation and Injury-Therapeutic Interventions
    John Lambris; Fiscal Year: 2007
    ..Each laboratory involved has developed well-defined model systems that will allow the dissection of the critical components and mechanisms by which the complement system participates in cell survival or ..
  13. QUANTITATIVE GENETIC STUDY OF SEIZURES
    Thomas N Ferraro; Fiscal Year: 2012
    ..As a result of the success achieved in the dissection and translation of the distal Chr 1 QTL (Szs1) in the B6- D2 model, we have recently (February 2008) submitted a ..
  14. QUANTITATIVE GENETIC STUDY OF SEIZURES
    Thomas N Ferraro; Fiscal Year: 2010
    ..As a result of the success achieved in the dissection and translation of the distal Chr 1 QTL (Szs1) in the B6- D2 model, we have recently (February 2008) submitted a ..
  15. QUANTITATIVE GENETIC STUDY OF SEIZURES
    THOMAS FERRARO; Fiscal Year: 2009
    ..As a result of the success achieved in the dissection and translation of the distal Chr 1 QTL (Szs1) in the B6- D2 model, we have recently (February 2008) submitted a ..
  16. HLA and schizophrenia: a high-throughput sequencing study
    DOUGLAS FREDERICK LEVINSON; Fiscal Year: 2012
    ..HLA alleles have not been directly typed in any large schizophrenia sample. Dissection of HLA effects typically requires testing of a large discovery sample and of samples from additional ethnic ..
  17. GENETIC ANALYSIS OF PURINE METABOLISM IN LEISHMANIA DONO
    Buddy Ullman; Fiscal Year: 2007
    ..structural biology, and computational chemistry this proposal offers a[unreadable] multidisciplinary dissection of the hypoxanthine-guanine[unreadable] phosphoribosyltransferase (HGPRT) enzyme from Leishmania donovani, an[..
  18. COORDINATE HORMONAL REGULATION OF THE FIBRINOGEN GENES
    LENE HOLLAND; Fiscal Year: 1992
    ..Therefore, this experimentally-manipulable system is ideal for a detailed dissection of the multiple elements involved in hormone responsiveness...
  19. Functional Genomic Dissection of Refractory Anemia
    BENJAMIN LEVINE EBERT; Fiscal Year: 2010
    ..We aim to understand how these deletions cause anemia and MDS and to identify novel therapeutic strategies for patients with these genetic deletions. ..
  20. Immunologic Basis of Cow's Milk-Induced Hypersensitivities
    Hugh Sampson; Fiscal Year: 2010
    ..characterized including their 3-dimensional structures, and good animal models have been established that enable dissection of immunologic and systemic mechanisms at the molecular level...
  21. Immunologic Basis of Cow's Milk-Induced Hypersensitivities
    Hugh Sampson; Fiscal Year: 2009
    ..characterized including their 3-dimensional structures, and good animal models have been established that enable dissection of immunologic and systemic mechanisms at the molecular level...
  22. Immunologic Basis of Cow's Milk-Induced Hypersensitivities
    Hugh Sampson; Fiscal Year: 2009
    ..characterized including their 3-dimensional structures, and good animal models have been established that enable dissection of immunologic and systemic mechanisms at the molecular level...
  23. Forebrain angiogenesis in Foxc1 mutant mice
    Julie Siegenthaler; Fiscal Year: 2010
    ..Pleasure, including general lab equipment, centrifuges, freezers, a dissection room and adjacent tissue culture hood and incubators, microscopes, and space in the animal facility...
  24. MOLECULAR DISSECTION OF E. HISTOLYTICA PATHOGENESIS
    WILLIAM STENSON; Fiscal Year: 2009
    ..Jr. The name of the principal investigator/programdirector must be provided at the top of each printed page and each continuation page. RESEARCH GRANT TABLE OFCONTENTS Page Numbers Face Page 1 Description, ..
  25. MOLECULAR DISSECTION OF E. HISTOLYTICA PATHOGENESIS
    William F Stenson; Fiscal Year: 2010
    ..Jr. The name of the principal investigator/programdirector must be provided at the top of each printed page and each continuation page. RESEARCH GRANT TABLE OFCONTENTS Page Numbers Face Page 1 Description, ..
  26. Role of JAK2-PAK1 interaction in prolactin-dependent signaling
    Maria Diakonova; Fiscal Year: 2010
    ..Identification of the proteins recruited to the PRLR-JAK2 and dissection of the signaling pathways that are subsequently activated will ultimately provide a basis for understanding PRL ..
  27. Identification of Proteins Important for Male Osteoporosis
    Hong Wen Deng; Fiscal Year: 2009
    ..Proteomics is a powerful state-of-the-art strategy in genetic dissection of complex diseases, such as osteoporosis...
  28. Acupuncture for shoulder syndrome after cancer surgery
    David Pfister; Fiscal Year: 2003
    BACKGROUND: Neck dissection is a common procedure for treatment of head and neck cancer...
  29. Acupuncture for shoulder syndrome after ca surgery
    David Pfister; Fiscal Year: 2004
    BACKGROUND: Neck dissection is a common procedure for treatment of head and neck cancer...
  30. GSK3-beta Signaling in Medullary Thyroid Cancer
    Herbert Chen; Fiscal Year: 2012
    ..almost all patients will have persistent or recurrent disease after total thyroidectomy and central lymph node dissection. Moreover, there is no effective alternative to treat many of the debilitating symptoms associated with ..
  31. GSK3-beta Signaling in Medullary Thyroid Cancer
    Herbert Chen; Fiscal Year: 2010
    ..almost all patients will have persistent or recurrent disease after total thyroidectomy and central lymph node dissection. Moreover, there is no effective alternative to treat many of the debilitating symptoms associated with ..
  32. GSK3-beta Signaling in Medullary Thyroid Cancer
    Herbert Chen; Fiscal Year: 2009
    ..almost all patients will have persistent or recurrent disease after total thyroidectomy and central lymph node dissection. Moreover, there is no effective alternative to treat many of the debilitating symptoms associated with ..
  33. GSK3-beta Signaling in Medullary Thyroid Cancer
    Herbert Chen; Fiscal Year: 2011
    ..almost all patients will have persistent or recurrent disease after total thyroidectomy and central lymph node dissection. Moreover, there is no effective alternative to treat many of the debilitating symptoms associated with ..
  34. GSK3-beta Signaling in Medullary Thyroid Cancer
    Herbert Chen; Fiscal Year: 2010
    ..almost all patients will have persistent or recurrent disease after total thyroidectomy and central lymph node dissection. Moreover, there is no effective alternative to treat many of the debilitating symptoms associated with ..
  35. GENETIC DISSECTION OF SLE PATHOGENESIS
    Edward Wakeland; Fiscal Year: 2009
    ..Sle1 mice causes a breach in tolerance in the immature B cell compartment. We will determine whether Sles1 suppression of B6.Sle1 is mediated by correcting the breach in tolerance in immature B cells. ..
  36. GENETIC DISSECTION OF SLE PATHOGENESIS
    Edward Wakeland; Fiscal Year: 2007
    ..Sle1 mice causes a breach in tolerance in the immature B cell compartment. We will determine whether Sles1 suppression of B6.Sle1 is mediated by correcting the breach in tolerance in immature B cells. ..
  37. GENETIC DISSECTION OF SLE PATHOGENESIS
    Edward K Wakeland; Fiscal Year: 2010
    ..Sle1 mice causes a breach in tolerance in the immature B cell compartment. We will determine whether Sles1 suppression of B6.Sle1 is mediated by correcting the breach in tolerance in immature B cells. ..
  38. Genetic Dissection of Auditory Circuit Assembly
    LISA GOODRICH; Fiscal Year: 2009
    ....
  39. MOLECULAR DISSECTION OF CONGENITAL NEPHROGENIC DI
    ROBERT WILDIN; Fiscal Year: 2000
    ..The structure-function implications of the V2 ADHR mutation analysis will also contribute to a fuller understanding of STM receptors in general. ..
  40. MOLECULAR DISSECTION OF CONGENITAL NEPHROGENIC DI
    ROBERT WILDIN; Fiscal Year: 1999
    ..The structure-function implications of the V2 ADHR mutation analysis will also contribute to a fuller understanding of STM receptors in general. ..
  41. GENETIC DISSECTION OF AGGRESSIVE BEHAVIOR OF HONEY BEES
    Greg Hunt; Fiscal Year: 1999
    ..3 cM with 95% confidence. It is proposed to use STS primers designed from the RAPD markers, SSCP polymorphisms and further development of another set of RAPD markers from 1000 10-mer primers, screened in bulk. ..
  42. GENETIC DISSECTION OF AGGRESSIVE BEHAVIOR OF HONEY BEES
    Greg Hunt; Fiscal Year: 2000
    ..3 cM with 95% confidence. It is proposed to use STS primers designed from the RAPD markers, SSCP polymorphisms and further development of another set of RAPD markers from 1000 10-mer primers, screened in bulk. ..
  43. Role of the Spx Regulator in Streptococcus mutans
    JOSE A LEMOS; Fiscal Year: 2010
    ..Because stress tolerance is intertwined with S. mutans virulence, the dissection of the mechanisms that allow these bacteria to thrive in oral biofilms during stressful conditions is central ..
  44. GENETIC DISSECTION OF PHOTOTRANSDUCTION
    Baruch Minke; Fiscal Year: 1993
    ..The experiments proposed here offer a means for studying these clinical disorders at the basic biochemical and physiological levels...
  45. Purine Salvage Pathway of Cryptosporidium Parvum
    Buddy Ullman; Fiscal Year: 2010
    ..cell biology, genetics, structural biology, and pharmacology, this proposal offers an interdisciplinary dissection of the purine salvage pathway of Cryptosporidium parvum, a protozoan parasite that is an opportunistic pathogen ..
  46. Purine Salvage Pathway of Cryptosporidium Parvum
    Buddy Ullman; Fiscal Year: 2009
    ..cell biology, genetics, structural biology, and pharmacology, this proposal offers an interdisciplinary dissection of the purine salvage pathway of Cryptosporidium parvum, a protozoan parasite that is an opportunistic pathogen ..
  47. Internal Polymeric Vessel Occluder for Temporary Vascular Occlusion of the Kidney
    PETER MADRAS; Fiscal Year: 2007
    ..including conventional suture repair, tissue sealants, radiofrequency ablation, laser ablation, water dissection, and microwave tissue coagulation...
  48. Molecular Dissection of the Permeability Transition Pore
    Michael Forte; Fiscal Year: 2006
    ..abstract_text> ..
  49. Molecular Dissection of the Permeability Transition Pore
    Michael Forte; Fiscal Year: 2005
    ..abstract_text> ..
  50. Molecular Dissection of the Permeability Transition Pore
    Michael Forte; Fiscal Year: 2004
    ..abstract_text> ..
  51. Molecular Dissection of the Permeability Transition Pore
    Michael Forte; Fiscal Year: 2007
    ..abstract_text> ..
  52. Extracellular Matrix Metabolism in Thoracic Aortic Aneurysm and Dissection
    Joseph Coselli; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Although thoracic aortic aneurysm and dissection (TAAD) are not as common as some forms of vascular diseases, e.g. coronary artery disease, it is a clinically insidious disease with high fatality...
  53. Genetic and Genomic Dissection of Psoriatic Arthritis
    JAMES TILFORD ELDER; Fiscal Year: 2012
    ..The results of this research are also likely to be relevant to other autoimmune diseases. ..
  54. Microfibril Fragments: Biomarkers of Aortic Disease
    Lynn Y Sakai; Fiscal Year: 2010
    Develop technologies for assessment of aortic aneurysms prone to rupture or dissection. Thoracic and abdominal aortic aneurysms (TAA and AAA) are life threatening conditions that comprise the thirteenth leading cause of death in the ..
  55. Microfibril Fragments: Biomarkers of Aortic Disease
    Lynn Sakai; Fiscal Year: 2009
    Develop technologies for assessment of aortic aneurysms prone to rupture or dissection. Thoracic and abdominal aortic aneurysms (TAA and AAA) are life threatening conditions that comprise the thirteenth leading cause of death in the ..
  56. HGF Induces Robust Human Thymopoiesis in Mice
    Jan Nolta; Fiscal Year: 2003
    ..stem cells; the fetal thymic organ culture, requires precise timed mating of murine breeders and then careful dissection of the resulting day 15 embryos. When successful, the technique produces very low numbers of human T cells...
  57. HGF Induces Robust Human Thymopoiesis in Mice
    Jan Nolta; Fiscal Year: 2004
    ..stem cells; the fetal thymic organ culture, requires precise timed mating of murine breeders and then careful dissection of the resulting day 15 embryos. When successful, the technique produces very low numbers of human T cells...
  58. E PROTEIN AND B CELL DIFFERENTIATION
    Cornelis Murre; Fiscal Year: 2007
    ..We would further characterize the role of E-proteins in the regulation AID transcription. Overall the dissection of the roles of E2A in B cell development should help to clarify the mechanism by how E-proteins regulate B ..
  59. MOLECULAR DISSECTION OF DOPAMINE D5 RECEPTOR ACTIONS
    David Grandy; Fiscal Year: 1993
    ..The production of these "knockout" mice will provide a new and powerful mouse model system in which the role of dopamine D5 receptors in renal physiology in general, and sodium transport in particular, can be evaluated...
  60. CONTROL OF RETINAL GENES BY THE OPTIC NERVE ENVIRONMENT
    J H Skene; Fiscal Year: 1990
    ..To permit a detailed molecular dissection of at least one se of such retrograde signals, this work has focused on a single gene, encoding a protein ..
  61. Magneto-motive ultrasound imaging using molecular specific nanoparticles
    STANISLAV EMELIANOV; Fiscal Year: 2009
    ..More definitive information about the status of the regional nodes can be obtained from elective lymph node dissection (ELND), lymphoscintigraphy with sentinel node biopsy (LSNB), or fine needle aspiration...
  62. Magneto-motive ultrasound imaging using molecular specific nanoparticles
    Stanislav Y Emelianov; Fiscal Year: 2010
    ..More definitive information about the status of the regional nodes can be obtained from elective lymph node dissection (ELND), lymphoscintigraphy with sentinel node biopsy (LSNB), or fine needle aspiration...
  63. Endoscopic Detection of Fluorescein for Sentinel Lymph Node Biopsy
    James McGreevy; Fiscal Year: 2006
    ..This new device will allow the surgeon to perform the axillary dissection of lymph nodes in breast cancer patients with minimally-invasive surgical techniques...
  64. Endoscopic Detection of Fluorescein for Sentinel Lymph Node Biopsy
    James McGreevy; Fiscal Year: 2007
    ..This new device will allow the surgeon to perform the axillary dissection of lymph nodes in breast cancer patients with minimally-invasive surgical techniques...
  65. DISSECTION OF THE FUNCTIONS OF HERPES SIMPLEX VIRUS ICPO
    Bernard Roizman; Fiscal Year: 2005
    ..We expect that the proposed studies will help understand the role of ICP0 in the evolution of diseases caused by HSV-1 and HSV-2. ..
  66. DISSECTION OF THE FUNCTIONS OF HERPES SIMPLEX VIRUS ICPO
    Bernard Roizman; Fiscal Year: 2006
    ..We expect that the proposed studies will help understand the role of ICP0 in the evolution of diseases caused by HSV-1 and HSV-2. ..
  67. Assembly Line Biosynthesis of Bacterial Siderophores
    JORGE CROSA; Fiscal Year: 2009
    ..The specific aims are: 1. Dissection of the mechanisms of assembly line enzymology in anguibactin biosynthesis...
  68. DISSECTION OF THE FUNCTIONS OF HERPES SIMPLEX VIRUS ICPO
    Bernard Roizman; Fiscal Year: 2007
    ..We expect that the proposed studies will help understand the role of ICP0 in the evolution of diseases caused by HSV-1 and HSV-2. ..
  69. DISSECTION OF THE FUNCTIONS OF HERPES SIMPLEX VIRUS ICPO
    Bernard Roizman; Fiscal Year: 2003
    ..We expect that the proposed studies will help understand the role of ICP0 in the evolution of diseases caused by HSV-1 and HSV-2. ..
  70. DISSECTION OF THE FUNCTIONS OF HERPES SIMPLEX VIRUS ICPO
    Bernard Roizman; Fiscal Year: 2004
    ..We expect that the proposed studies will help understand the role of ICP0 in the evolution of diseases caused by HSV-1 and HSV-2. ..
  71. Assembly Line Biosynthesis of Bacterial Siderophores
    JORGE CROSA; Fiscal Year: 2009
    ..The specific aims are: 1. Dissection of the mechanisms of assembly line enzymology in anguibactin biosynthesis...
  72. Chemical dissection of phospho-signaling that controls the caulobacter cell cycle
    JAMES CHRISTIANSEN ABELLERA BLAIR; Fiscal Year: 2010
    ..Since small molecule inhibitors will allow temporal dissection of the Caulobacter cell cycle, the experiments involve developing chemical inhibitors of signal transduction ..
  73. Chemical dissection of phospho-signaling that controls the caulobacter cell cycle
    JAMES CHRISTIANSEN BLAIR; Fiscal Year: 2009
    ..Since small molecule inhibitors will allow temporal dissection of the Caulobacter cell cycle, the experiments involve developing chemical inhibitors of signal transduction ..
  74. GENETIC DISSECTION OF ALCOHOL/RETINOL METABOLIC PATHWAYS
    Gregg Duester; Fiscal Year: 2002
    ..3) Prepare and ALDH-I knockout mouse plus mice mutated for one or more ADHs and ALDH-I, then analyze their phenotype as above. ..
  75. GENETIC DISSECTION OF ALCOHOL/RETINOL METABOLIC PATHWAYS
    Gregg Duester; Fiscal Year: 2000
    ..3) Prepare and ALDH-I knockout mouse plus mice mutated for one or more ADHs and ALDH-I, then analyze their phenotype as above. ..
  76. GENETIC DISSECTION OF ALCOHOL/RETINOL METABOLIC PATHWAYS
    Gregg Duester; Fiscal Year: 1999
    ..3) Prepare and ALDH-I knockout mouse plus mice mutated for one or more ADHs and ALDH-I, then analyze their phenotype as above. ..
  77. Functional characterization of SSRI resistant genes using C. elegans
    JI Y SZE; Fiscal Year: 2010
    The goal of this proposal is to elucidate the serotonin signaling pathways through genetic dissection of genes and functional pathways regulated by Selective Serotonin Reuptake Inhibitors (SSRIs)...
  78. Kinetic Dissection of the RNA Chaperone Protein CYT-19
    Rick Russell; Fiscal Year: 2005
    The proposed research is a dissection of the targeting and action of the RNA chaperone CYT-19 protein as it facilitates folding of a group I RNA...
  79. Kinetic Dissection of the RNA Chaperone Protein CYT-19
    Rick Russell; Fiscal Year: 2004
    The proposed research is a dissection of the targeting and action of the RNA chaperone CYT-19 protein as it facilitates folding of a group I RNA...
  80. Kinetic Dissection of the RNA Chaperone Protein CYT-19
    Rick Russell; Fiscal Year: 2007
    The proposed research is a dissection of the targeting and action of the RNA chaperone CYT-19 protein as it facilitates folding of a group I RNA...
  81. Functional characterization of SSRI resistant genes using C. elegans
    JI SZE; Fiscal Year: 2009
    The goal of this proposal is to elucidate the serotonin signaling pathways through genetic dissection of genes and functional pathways regulated by Selective Serotonin Reuptake Inhibitors (SSRIs)...
  82. A Sex-Specific Dissection of Autism Genetics
    Lauren Weiss; Fiscal Year: 2009
    ..With better understanding of the biological basis and the genetic architecture of autism, diagnosis, prognosis, prevention and treatment options could be improved. ..
  83. GENETIC DISSECTION OF ALCOHOL/RETINOL METABOLIC PATHWAYS
    Gregg Duester; Fiscal Year: 2001
    ..3) Prepare and ALDH-I knockout mouse plus mice mutated for one or more ADHs and ALDH-I, then analyze their phenotype as above. ..
  84. Kinetic Dissection of the RNA Chaperone Protein CYT-19
    Rick Russell; Fiscal Year: 2006
    The proposed research is a dissection of the targeting and action of the RNA chaperone CYT-19 protein as it facilitates folding of a group I RNA...
  85. Molecular genetic dissection of central amygdala microcircuitry underlying fear a
    David Anderson; Fiscal Year: 2009
    ..These studies should begin to provide a functional dissection of the amygdala at the level of granularity of specific neuronal subtypes, and may identify new cellular targets ..
  86. Dissection of the mosquito Aedes Aegypti's immune responses to Dengue infection.
    Jose Ramirez; Fiscal Year: 2009
    ..Transcriptional dissection of tissue and stage specific immune responses will be elucidated through whole genome microarray assays and ..
  87. GENETIC DISSECTION OF TOXOPLASMA GONDII
    David Roos; Fiscal Year: 2007
    ..In addition to their value for the analysis of folate metabolism[unreadable] and drug resistance, these tools should be broadly applicable to other[unreadable] studies on the biology and biochemistry of Toxoplasma.[unreadable]..