ileostomy

Summary

Summary: Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.

Top Publications

  1. doi Complications of loop ileostomy closure: a retrospective cohort analysis of 123 patients
    S D Mansfield
    Department of General Surgery, North Tyneside General Hospital, Rake Lane, North Shields, Tyne and Wear, NE29 8NH, UK
    World J Surg 32:2101-6. 2008
  2. ncbi Stoma-related complications are more frequent after transverse colostomy than loop ileostomy: a prospective randomized clinical trial
    D P Edwards
    Colorectal Research Unit, North Hampshire Hospital, Aldermaston Road, Basingstoke RG24 9NA, UK
    Br J Surg 88:360-3. 2001
  3. ncbi Comparison of stapled versus handsewn loop ileostomy closure: a meta-analysis
    Terry T W Leung
    Department of Surgery, University of Calgary, Room 1014, North Tower, Foothills Medical Centre, 1403 29 St NW, Calgary, AB, Canada T2N 2T9
    J Gastrointest Surg 12:939-44. 2008
  4. ncbi Complications of construction and closure of temporary loop ileostomy
    Orit Kaidar-Person
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston 33331, USA
    J Am Coll Surg 201:759-73. 2005
  5. ncbi Loop ileostomy (decompression type) using polytetrafluroethylene
    Seyed Vahid Hosseini
    Department of Colorectal Surgery, Gastroenterohepatology Research Center, School of Medicine, Shiraz University of Medical Sciences, P O Box 71345 1744, Shiraz, Iran
    Arch Iran Med 9:410-2. 2006
  6. doi Single incision ("scarless") laparoscopic total abdominal colectomy with end ileostomy for ulcerative colitis
    Alessandro Fichera
    Department of Surgery, University of Chicago Medical Center, 5841 S Maryland Ave, MC 5095, Chicago, IL 60637, USA
    J Gastrointest Surg 15:1247-51. 2011
  7. ncbi A defunctioning ileostomy does not prevent clinical anastomotic leak after a low anterior resection: a prospective, comparative study
    N Y Wong
    Department of Colorectal Surgery, Singapore General Hospital, Singapore
    Dis Colon Rectum 48:2076-9. 2005
  8. doi Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery
    Norbert Hüser
    Department of Surgery, Technische Universitat Munchen, Munich, Germany
    Ann Surg 248:52-60. 2008
  9. doi Loop ileostomy closure: comparison of cost effectiveness between suture and stapler
    Karoline Horisberger
    Department of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, 3010, Bern, Switzerland
    World J Surg 34:2867-71. 2010
  10. ncbi The outcome of loop ileostomy closure: a prospective study
    L A Williams
    Department of Colorectal Surgery, The General Infirmary at Leeds, Leeds, UK
    Colorectal Dis 10:460-4. 2008

Research Grants

  1. Acupuncture to Prevent Postoperative Paralytic lleus
    JOSEPH CHIANG; Fiscal Year: 2004
  2. Smart Seal Ostomy Appliance
    JEFFREY SCHOESS; Fiscal Year: 2005
  3. Smart Seal Ostomy Appliance
    JEFFREY SCHOESS; Fiscal Year: 2006
  4. HR-QOL in Colorectal Cancer Survivors with Stomas
    Robert Krouse; Fiscal Year: 2006
  5. HR-QOL in Colorectal Cancer Survivors with Stomas
    ROBERT S contact KROUSE; Fiscal Year: 2010
  6. Pilot study on the safety and efficacy of ciprofloxacin for prophylactic preventi
    Hans Herfarth; Fiscal Year: 2007
  7. Smart Seal Ostomy Appliance
    JEFFREY SCHOESS; Fiscal Year: 2002
  8. HR-QOL in Colorectal Cancer Survivors with Stomas
    Robert Krouse; Fiscal Year: 2009
  9. IKSI: 1st Annual International Urolithiasis Research Symposium
    Andrew Evan; Fiscal Year: 2007
  10. Risk for Renal Injury Caused by Shock Wave Lithotripsy
    Andrew Evan; Fiscal Year: 2007

Detail Information

Publications207 found, 100 shown here

  1. doi Complications of loop ileostomy closure: a retrospective cohort analysis of 123 patients
    S D Mansfield
    Department of General Surgery, North Tyneside General Hospital, Rake Lane, North Shields, Tyne and Wear, NE29 8NH, UK
    World J Surg 32:2101-6. 2008
    ..Loop ileostomies are often formed in order to defunction distal anastomoses. The aim of this study was to review the complications following closure of loop ileostomies...
  2. ncbi Stoma-related complications are more frequent after transverse colostomy than loop ileostomy: a prospective randomized clinical trial
    D P Edwards
    Colorectal Research Unit, North Hampshire Hospital, Aldermaston Road, Basingstoke RG24 9NA, UK
    Br J Surg 88:360-3. 2001
    ..Controversy continues as to whether loop ileostomy (LI) or loop transverse colostomy (LTC) is the optimal method of defunctioning such anastomoses...
  3. ncbi Comparison of stapled versus handsewn loop ileostomy closure: a meta-analysis
    Terry T W Leung
    Department of Surgery, University of Calgary, Room 1014, North Tower, Foothills Medical Centre, 1403 29 St NW, Calgary, AB, Canada T2N 2T9
    J Gastrointest Surg 12:939-44. 2008
    ..search in Embase, PubMed, and Cochrane Database for Clinical Trials using search terms "closure," "loop ileostomy," and "stapled" was performed...
  4. ncbi Complications of construction and closure of temporary loop ileostomy
    Orit Kaidar-Person
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston 33331, USA
    J Am Coll Surg 201:759-73. 2005
  5. ncbi Loop ileostomy (decompression type) using polytetrafluroethylene
    Seyed Vahid Hosseini
    Department of Colorectal Surgery, Gastroenterohepatology Research Center, School of Medicine, Shiraz University of Medical Sciences, P O Box 71345 1744, Shiraz, Iran
    Arch Iran Med 9:410-2. 2006
  6. doi Single incision ("scarless") laparoscopic total abdominal colectomy with end ileostomy for ulcerative colitis
    Alessandro Fichera
    Department of Surgery, University of Chicago Medical Center, 5841 S Maryland Ave, MC 5095, Chicago, IL 60637, USA
    J Gastrointest Surg 15:1247-51. 2011
    ..In this article, we describe our technique in performing the single-incision total abdominal colectomy...
  7. ncbi A defunctioning ileostomy does not prevent clinical anastomotic leak after a low anterior resection: a prospective, comparative study
    N Y Wong
    Department of Colorectal Surgery, Singapore General Hospital, Singapore
    Dis Colon Rectum 48:2076-9. 2005
    Defunctioning ileostomy or colostomy is still routinely performed after low anterior resection in the belief that diverting the fecal stream will prevent anastomotic dehiscence...
  8. doi Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery
    Norbert Hüser
    Department of Surgery, Technische Universitat Munchen, Munich, Germany
    Ann Surg 248:52-60. 2008
    ..The role of a defunctioning stoma in patients undergoing low anterior resection for rectal cancer is still the subject of controversy. Recent studies suggest reduced morbidity after low anterior rectal resection with a defunctioning stoma...
  9. doi Loop ileostomy closure: comparison of cost effectiveness between suture and stapler
    Karoline Horisberger
    Department of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, 3010, Bern, Switzerland
    World J Surg 34:2867-71. 2010
    Closure of loop ileostomy can be safely performed using sutures or staplers. The aim of the present study was to compare the cost effectiveness of three different techniques.
  10. ncbi The outcome of loop ileostomy closure: a prospective study
    L A Williams
    Department of Colorectal Surgery, The General Infirmary at Leeds, Leeds, UK
    Colorectal Dis 10:460-4. 2008
    The use of a loop ileostomy is an effective method to protect pelvic anastomoses, although there is some debate as to the routine use of a stoma. A second operation is required to close the stoma, with potential complications.
  11. doi Complications of loop ileostomy closure in patients with rectal tumor
    Takashi Akiyoshi
    Gastroenterological Center, Department of Gastroenterological Surgery, Cancer Institute Ariake Hospital, 3 10 6 Ariake, Koto ku, Tokyo, 135 8550, Japan
    World J Surg 34:1937-42. 2010
    Loop ileostomy is customary after very low rectal anastomosis to reduce the rate of pelvic sepsis that can result from anastomotic leakage...
  12. ncbi The outcome after restorative proctocolectomy with or without defunctioning ileostomy
    Feza H Remzi
    Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dis Colon Rectum 49:470-7. 2006
    Controversy exists regarding the safety for omission of diverting ileostomy in restorative proctocolectomy because of fears of increased septic complications...
  13. doi Stapled ileostomy closure results in reduction of postoperative morbidity
    Y A Shelygin
    Department of Rectal Cancer Surgery, State Research Center of Coloproctology, Salyam Adyl st 2, 123423, Moscow, Russia
    Tech Coloproctol 14:19-23. 2010
    Loop ileostomy is widely employed as a defunctioning procedure for left-sided colonic anastomoses. Closure of the stoma carries a risk of morbidity and even mortality...
  14. ncbi Does sodium hyaluronate- and carboxymethylcellulose-based bioresorbable membrane (Seprafilm) decrease operative time for loop ileostomy closure?
    M Salum
    Cleveland Clinic Florida, Weston, FL 33331, USA
    Tech Coloproctol 10:187-90; discussion 190-1. 2006
    Adhesions can result in serious clinical complications and make ileostomy closure, which is relatively simple procedure into a complicated and prolonged one...
  15. doi Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome
    Ida B Gottschalck
    Sanos Bioscience, Copenhagen, Denmark
    Scand J Gastroenterol 43:1304-10. 2008
    ..PTH secretion in response to GLP-2 was also investigated in colectomized SBS patients and colectomized controls (with ileostomy).
  16. ncbi A prospective audit of the complications of loop ileostomy construction and takedown
    S A García-Botello
    Colorectal Surgery Unit, Hospital Clinico, University of Valencia, Spain
    Dig Surg 21:440-6. 2004
    A prospective review of the complications of ileostomy construction and takedown.
  17. ncbi Loop ileostomy versus loop colostomy for defunctioning low anastomoses during rectal cancer surgery
    E Rullier
    Department of Digestive Surgery, Saint Andre Hospital, 1 rue Jean Burguet, 33075 Bordeaux, France
    World J Surg 25:274-7; discussion 277-8. 2001
    Several studies have compared loop ileostomy with loop colostomy to defunction colorectal anastomoses. The discordant results may be due to the heterogeneity of the indications...
  18. ncbi Quality of life in patients with an ileostomy
    M Scarpa
    Surgery I, Department of Surgical and Gastroenterologic Sciences, University of Padua, Padua, Italy
    Minerva Chir 59:23-9. 2004
    Temporary or permanent ileostomy is a common procedure in colorectal surgery. Our aim was to assess the impact of ileostomy on quality of life and the relevant risk factors.
  19. pmc Dynamics of mucosal permeability and inflammation in collagenous colitis before, during, and after loop ileostomy
    A Munch
    Department of Gastroenterology, UHL, Linkoping, Sweden
    Gut 54:1126-8. 2005
    ..We describe a female patient with intractable collagenous colitis who was treated with a temporary loop ileostomy. She was followed clinically, histopathologically, and functionally by measuring mucosal permeability before ..
  20. ncbi Total abdominal colectomy, pelvic peritonectomy, and end-ileostomy for the surgical palliation of mucinous peritoneal carcinomatosis from non-gynecologic cancer
    Konstantinos M Stamou
    Washington Cancer Institute, Washington Hospital Center, NW, Washington, DC 20010, USA
    J Surg Oncol 83:197-203. 2003
    ..Historic controls of surgical efforts report high postoperative mortality and morbidity rates with equivocal palliation. Novel surgical procedures need to be tested in terms of the impact on survival and quality of life...
  21. ncbi Use of the pylorus for preventing ileostomy complications. An experimental canine study
    G Toubanakis
    Athens University Medical School, First Department of Propedeutic Surgery, Athens, Greece
    Dis Colon Rectum 39:266-9. 1996
    PURPOSE: Conventional ileostomy, as it is well known, presents with persistent watery diarrhea, among other complications...
  22. ncbi Mixed-linked beta-glucan from breads of different cereals is partly degraded in the human ileostomy model
    B Sundberg
    Department of Food Science, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Am J Clin Nutr 64:878-85. 1996
    ..degradation of beta-glucan in the small intestine and the molecular weight of beta-glucan in the excreta of nine ileostomy subjects after consumption of different diets based on bread made with oat bran (oat bread), a fiber-rich barley ..
  23. ncbi Health-related quality of life and pouch function in continent ileostomy patients: a 30-year perspective
    Ina E K Berndtsson
    Colorectal Unit, Sahlgrenska University Hospital, Goteborg, Sweden
    Dis Colon Rectum 47:2131-7. 2004
    The principal aim of this study was to assess long-term pouch durability and health-related quality of life in an original series of patients operated on with a continent ileostomy.
  24. doi Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile associated disease
    Matthew D Neal
    Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Ann Surg 254:423-7; discussion 427-9. 2011
    ..To determine whether a minimally invasive, colon-preserving approach could serve as an alternative to total colectomy in the treatment of severe, complicated Clostridium difficile-associated disease (CDAD)...
  25. ncbi Is routine pouchogram prior to ileostomy closure in colonic J-pouch really necessary?
    G M da Silva
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida, USA
    Colorectal Dis 6:117-20. 2004
    ..If a diverting ileostomy is performed, a pouchogram is frequently performed prior to ileostomy closure...
  26. ncbi Quality of life of stoma patients: temporary ileostomy versus colostomy
    Michael Anthony Silva
    Department of General Surgery, University Surgical Unit, Teaching Hospital, Talagolla Road, Ragama, Sri Lanka
    World J Surg 27:421-4. 2003
    b>Ileostomy for proximal diversion as a preferred option over colostomy has been a recent topic of interest...
  27. ncbi Stapled ileoanal pouches without loop ileostomy: a prospective study in 86 patients
    K Gullberg
    Department of Surgery, Karolinska Institutet, Huddinge University Hospital, Sweden
    Int J Colorectal Dis 16:221-7. 2001
    ..offers an alternative to the hand-sewn technique following mucosectomy; a temporary defunctioning loop ileostomy may reduce the consequences of an anastomotic leakage, however it may entail discomfort for the patient, an ..
  28. ncbi Current indications for blow-hole colostomy:ileostomy procedure. A single center experience
    Feza H Remzi
    Department of Colorectal Surgery, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195 USA
    Int J Colorectal Dis 18:361-4. 2003
    Because of improved medical care and surgical techniques blow-hole colostomy with loop ileostomy is now rarely performed to reduce operative risks in patients with toxic megacolon related to inflammatory bowel disease (IBD)...
  29. doi Temporary percutaneous ileostomy versus conventional loop ileostomy in mechanical extraperitoneal colorectal anastomosis: a retrospective study
    F Rondelli
    University of Perugia, School of Medicine, Department of Surgery, Via G Dottori, 06132 Perugia, Italy
    Eur J Surg Oncol 38:1065-70. 2012
    Loop ileostomy is a suitable procedure for transitory faecal diversion after low colorectal anastomosis, but it causes relevant morbidities (discomfort, peristomal infections, dehydration) and requires a second operation to be closed...
  30. ncbi Durability of Kock continent ileostomy
    Anna H Lepistö
    Department of Surgery, Helsinki University Central Hospital, Finland
    Dis Colon Rectum 46:925-8. 2003
    The purpose of this study was to determine the cumulative success rate of Kock continent ileostomy and the reasons leading to excision and to compare the results with pelvic pouch and ileal pouch-anal anastomosis.
  31. ncbi Loop ileostomy morbidity: timing of closure matters
    Rodrigo Oliva Perez
    Institute of Colorectal Surgery, Rua Manuel da Nóbrega 1564, 04001 005 São Paulo, SP, Brazil
    Dis Colon Rectum 49:1539-45. 2006
    Diverting stomas are commonly performed during ileoanal and coloanal anastomoses. We studied a series of patients after loop ileostomy closure to determine risk factors and the impact of the interval from primary operation on morbidity.
  32. ncbi Routine use of gastrograffin enema prior to the reversal of a loop ileostomy
    G Khair
    Academic Surgical Unit, Castle Hill Hospital, Cottingham, Hull, UK
    Dig Surg 24:338-41. 2007
    Anastomotic failure occurs in up to 10% of patients following anterior resection. Selective use of a loop ileostomy may reduce the septic consequences of anastomotic leak...
  33. ncbi The failed pelvic pouch: conversion to a continent ileostomy
    L Borjesson
    Department of Surgery, Sahlgrenska University Hospital Ostra, SE 416 85 Goteborg, Sweden
    Tech Coloproctol 8:102-5. 2004
    Excision of the ileal pouch-anal anastomosis (IPAA) with construction of a conventional ileostomy is in general the ultimate procedure after unsuccessful salvage surgery...
  34. ncbi Behaviour of the pharmaceutical probiotic preparation VSL#3 in human ileostomy effluent containing its own natural elements
    B Bianchi-Salvadori
    Centro Sperimentale del Latte SpA, Zelo Buon Persico, Italy
    New Microbiol 24:23-33. 2001
    ..probiotic VSL#3 (300 billion cfu/g lactic acid bacteria & bifidobacteria) was inoculated into human ileostomy effluent (HIE) to assess its behaviour vs the ileo-caecal tract...
  35. ncbi Factors associated with failure in managing pelvic sepsis after ileal pouch-anal anastomosis (IPAA)--a multivariate analysis
    Ismail Sagap
    Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Surgery 140:691-703; discussion 703-4. 2006
    ..Pelvic sepsis is known to cause a detrimental outcome after ileal pouch-anal anastomosis (IPAA). The aim of this study was to examine potential factors associated with failure in managing pelvic sepsis after IPAA...
  36. doi Timely closure of loop ileostomy following anterior resection for rectal cancer
    M Chand
    Southampton General Hospital, Southampton, Hampshire, UK
    Eur J Cancer Care (Engl) 17:611-5. 2008
    The implications of constructing a temporary ileostomy as part of the primary surgery for some rectal cancers must not be underestimated and many patients are particularly keen to have their stoma closed as early as possible...
  37. doi Morbidity and complications of protective loop ileostomy
    G F Giannakopoulos
    Department of Surgery, VU Medical Center, HV Amsterdam, The Netherlands
    Colorectal Dis 11:609-12. 2009
    The creation of a loop ileostomy is considered suitable to protect a distal anastomosis in colorectal surgery. This technique is, however, associated with failure, complications and even mortality...
  38. doi Sushi-roll wrap of Seprafilm for ileostomy limbs facilitates ileostomy closure
    Y J Kawamura
    Department of Surgery, Saitama Medical Center, Jichi Medical University, Omiya ku, Saitama, Japan
    Tech Coloproctol 13:211-4. 2009
    Sodium hyaluronate and carboxymethylcellulose membrane (Seprafilm) reduced postoperative intraabdominal adhesion. In this study, we examined whether Seprafilm reduces operative difficulties in ileostomy closure.
  39. doi Quality of life after low anterior resection and temporary loop ileostomy
    Akira Tsunoda
    Department of General and Gastroenterological Surgery, Showa University School of Medicine, 1 5 8 Hatanodai, Shinagawa ku, Tokyo 142 8666, Japan
    Dis Colon Rectum 51:218-22. 2008
    ..This study was designed to evaluate the quality of life in patients undergoing low anterior resection with a temporary ileostomy.
  40. doi Postoperative morbidity with diversion after low anterior resection in the era of neoadjuvant therapy: a single institution experience
    Vassiliki L Tsikitis
    Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN 55905, USA
    J Am Coll Surg 209:114-8. 2009
    ....
  41. ncbi Loop ileostomy closure after restorative proctocolectomy: outcome in 1,504 patients
    Kutt Sing Wong
    Department of Colorectal Surgery, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Dis Colon Rectum 48:243-50. 2005
    Routine use of a temporary loop ileostomy for diversion after restorative proctocolectomy is controversial because of reported morbidity associated with its creation and closure...
  42. doi Enteral Clostridium difficile, an emerging cause for high-output ileostomy
    R N Williams
    Department of Surgery, Leicester Royal Infirmary, University Hospitals Leicester NHS Trust, Leicester, UK
    J Clin Pathol 62:951-3. 2009
    The loss of fluid and electrolytes from a high-output ileostomy (>1200 ml/day) can quickly result in dehydration and if not properly managed may cause acute renal failure...
  43. ncbi Intestinal absorption of different types of folate in healthy subjects with an ileostomy
    Erik J M Konings
    Nutrition and Toxicology Research Institute NUTRIM, Maastricht University, The Netherlands
    Br J Nutr 88:235-42. 2002
    ..Folate absorption was determined in healthy ileostomy volunteers (n 11) using a single-dose short-term protocol...
  44. ncbi The value of diverting loop ileostomy on the high-risk colon and rectal anastomosis
    Timothy W Bax
    Surgical Specialists of Spokane, 105 W 8th Avenue, Suite 7060, Spokane, WA 99203, USA
    Am J Surg 193:585-7; discussion 587-8. 2007
    ..This study was designed to evaluate the potential benefits and complications of diverting loop ileostomies in a high-risk anastomosis population...
  45. ncbi Successful local excision of ileostomy adenocarcinoma after colectomy for familial adenomatous polyposis: report of a case
    Toshiro Iizuka
    Department of Gastrointestinal Surgery, Toranomon Hospital, 2 2 2 Toranomon, Minato ku, Tokyo 105 0001, Japan
    Surg Today 32:638-41. 2002
    Primary adenocarcinoma rarely develops at the site of an ileostomy performed for ulcerative colitis (UC), familial adenomatous polyposis (FAP), or Crohn's disease...
  46. ncbi Human ileostomy glycoproteins as a model for small intestinal mucus to investigate adhesion of probiotics
    E M Tuomola
    Department of Biochemistry and Food Chemistry, University of Turku, Finland
    Lett Appl Microbiol 28:159-63. 1999
    Human ileostomy glycoproteins were used as a model for small intestinal mucus to investigate the adhesion of 12 Lactobacillus strains, one Lactococcus strain and one Propionibacterium strain, Both probiotic and dairy strains were tested...
  47. doi Bioavailability of anthocyanins and ellagitannins following consumption of raspberries by healthy humans and subjects with an ileostomy
    Rocío González-Barrio
    Graham Kerr Building, Division of Developmental Medicine, Faculty of Medicine, University of Glasgow, Glasgow, UK
    J Agric Food Chem 58:3933-9. 2010
    ..was studied following the consumption of 300 g of raspberries by healthy human volunteers and subjects with an ileostomy. Postingestion plasma and urine from the former and ileal fluid and urine from the latter group were collected ..
  48. doi Standardized postoperative pathway: accelerating recovery after ileostomy closure
    Yong Geul Joh
    Division of Colorectal Surgery, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    Dis Colon Rectum 51:1786-9. 2008
    In this study we evaluated the outcome of a standardized enhanced recovery program in patients undergoing ileostomy closure.
  49. ncbi Folate absorption from folate-fortified and processed foods using a human ileostomy model
    Cornelia M Witthöft
    Department of Food Science, Swedish University of Agricultural Sciences, P O Box 7051, SE 75007 Uppsala, Sweden
    Br J Nutr 95:181-7. 2006
    ..The aim of the present work was to study the effects from fortified and processed foods on folate absorption in ileostomy volunteers (n 9) using the area under the plasma concentration curve (AUC) and kinetic modelling...
  50. doi Quantification of isotope-labelled and unlabelled folates in plasma, ileostomy and food samples
    Barbara E Büttner
    Division BIOANALYTIK Weihenstephan, Research Center for Nutrition and Food Sciences Z I E L, Technische Universitat Munchen, 85350 Freising Weihenstephan, Germany
    Anal Bioanal Chem 399:429-39. 2011
    ..e. plasma, ileostomy samples, and food. The methods were based on clean-up by strong anion exchange followed by LC-MS/MS detection...
  51. ncbi T-tube ileostomy for intestinal perforation in extremely low birth weight neonates
    M Rygl
    Department of Pediatric Surgery, 2nd Faculty of Medicine and Teaching Hospital in Motol, Institute of Postgraduate Medicine, Charles University, V Uvalu 84, Prague 5, Czech Republic
    Pediatr Surg Int 23:685-8. 2007
    To evaluate the results of use of T-tube ileostomy in selected cases of intestinal perforation in extremely low birth weight (ELBW) neonates...
  52. ncbi K-ras mutation and loss of heterozygosity at 17p with beta-catenin accumulation in intramucosal carcinoma of the ileostomy in familial adenomatous polyposis: a case report
    Keisuke Hata
    Department of Surgical Oncology, University of Tokyo, Tokyo, Japan
    Dig Dis Sci 48:2310-4. 2003
  53. ncbi Wound infection after ileostomy closure: a prospective randomized study comparing primary vs. delayed primary closure techniques
    G Lahat
    Proctology Unit, Division of Surgery B, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Tech Coloproctol 9:206-8. 2005
    Closure of ileostomy is considered a contaminated operation. The infection rate of the stoma wound is > or = 30%. Several ileostomy-closure techniques intended to reduce the high rate of infection have been described in the literature...
  54. ncbi Quality of life after low anterior resection with total mesorectal excision and temporary loop ileostomy for rectal carcinoma
    D P O'Leary
    Department of Surgery, Gloucestershire Royal Hospital, Gloucester, UK
    Br J Surg 88:1216-20. 2001
    ..Routine formation of a temporary defunctioning stoma has been recommended with TME. The impact of this strategy on health-related quality of life (HRQOL) has not been addressed...
  55. pmc Defunctioning loop ileostomy and stapled side-to-side closure has low morbidity
    S N Amin
    Department of Surgery, Queen s Medical Centre, Nottingham, UK
    Ann R Coll Surg Engl 83:246-9. 2001
    ..Therefore, defunctioning loop ileostomies are being increasingly fashioned to protect against the consequences of a leak. However, the reported complication rates of such stoma creation and closure is between 5.7-69%...
  56. ncbi Bioavailability of polyphenon E flavan-3-ols in humans with an ileostomy
    Cyril Auger
    Plant Products and Human Nutrition Group, Division of Environmental and Evolutionary Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
    J Nutr 138:1535S-1542S. 2008
    To investigate the degree of absorption of flavan-3-ols in the small intestine, human subjects with an ileostomy ingested 200 mg of Polyphenon E, a green tea extract, after which ileal fluid and urine, collected over a 24-h period, were ..
  57. ncbi [Quality of life in patients treated with orthotopic bladder substitution versus cutaneous ileostomy]
    C Conde Redondo
    , Hospital Universitario Rio Hortega, Valladolid
    Actas Urol Esp 25:435-44. 2001
    ..CONCLUSION: Health-related quality of life is higher after bladder substitution. In our opinion we should use bladder substitution as the standard method of diversion after radical cystectomy for bladder cancer...
  58. doi Folate bioavailability from breads and a meal assessed with a human stable-isotope area under the curve and ileostomy model
    Veronica E Ohrvik
    Department of Food Science, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Am J Clin Nutr 92:532-8. 2010
    ..Recent data revealed differences in human absorption kinetics and metabolism between food folates and folic acid supplements and fortificant...
  59. ncbi Temporary transverse colostomy vs loop ileostomy in diversion: a case-matched study
    Y Sakai
    Division of Colon and Rectal Surgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Arch Surg 136:338-42. 2001
    HYPOTHESIS: For temporary fecal diversion, transverse colostomy (TC) has superior safety, but loop ileostomy (LI) has superior management qualities...
  60. doi Randomized clinical trial of short-term outcomes following purse-string versus conventional closure of ileostomy wounds
    K Reid
    Department of Colorectal Surgery, John Hunter Hospital, New South Wales, Australia
    Br J Surg 97:1511-7. 2010
    b>Ileostomy closure is an operation with an underappreciated morbidity, including surgical-site infection, small bowel obstruction and anastomotic leakage...
  61. doi Loop ileostomy versus loop colostomy for fecal diversion after colorectal or coloanal anastomosis: a meta-analysis
    F Rondelli
    Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy
    Int J Colorectal Dis 24:479-88. 2009
    ..In order to reduce leakage-related complications, surgeons often perform a derivative stoma, a loop ileostomy (LI), or a loop colostomy (LC), but to date, there is no evidence on which is the better technique to adopt.
  62. ncbi Primary closure of the skin after stoma closure. Management of wound infections is easy without (long-term) complications
    N Vermulst
    Department of Surgery, Medisch Centrum Rijnmond Zuid, NL 3078 HT Rotterdam, The Netherlands
    Dig Surg 23:255-8. 2006
    ..Therefore, this present study was undertaken to compare the complications and consequences between primary or delayed closure of the skin after stoma closure...
  63. doi Comparison of outcomes after restorative proctocolectomy with or without defunctioning ileostomy
    Gina K Weston-Petrides
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, 10th Floor, QEQM Wing, Praed Street, London W2 1NY, England
    Arch Surg 143:406-12. 2008
    ..To evaluate postoperative adverse events and functional outcomes of patients undergoing restorative proctocolectomy with or without proximal diversion...
  64. doi Absorption, metabolism, and excretion of green tea flavan-3-ols in humans with an ileostomy
    Angelique Stalmach
    Division of Environmental and Evolutionary Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, UK
    Mol Nutr Food Res 54:323-34. 2010
    Green tea containing 634 micromol of flavan-3-ols was ingested by human subjects with an ileostomy. Ileal fluid, plasma, and urine collected 0-24 h after ingestion were analysed by HPLC-MS...
  65. ncbi Predictors for complications after loop stoma closure in patients with rectal cancer
    Herwig Pokorny
    Department of Surgery, University Hospital of Vienna, 21A Währinger Gürtel 18 20, 1090, Vienna, Austria
    World J Surg 30:1488-93. 2006
    ..This unmatched case control study was undertaken to evaluate factors contributing to surgery-related complications of loop stoma closure in patients with rectal cancer...
  66. ncbi Randomized clinical trial comparing loop ileostomy and loop transverse colostomy for faecal diversion following total mesorectal excision
    W L Law
    Department of Surgery, Queen Mary Hospital, University of Hong Kong Medical Centre, 102 Pokfulam Road, Hong Kong
    Br J Surg 89:704-8. 2002
    The aim of this study was to compare loop ileostomy and loop transverse colostomy as the preferred mode of faecal diversion following low anterior resection with total mesorectal excision for rectal cancer.
  67. doi Clostridium difficile enteritis: a cause for high ileostomy output
    Mohammad Sami H El Muhtaseb
    ANZ J Surg 78:416. 2008
  68. doi Diverting stoma after low anterior resection: more arguments in favor
    Alexis B Ulrich
    Department of General Surgery, Visceral Surgery, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany
    Dis Colon Rectum 52:412-8. 2009
    ..We conducted a randomized, controlled, pilot-study to evaluate the need for diverting ileostomy in patients undergoing low anterior resection [NCT00457327].
  69. ncbi Bioresorbable adhesion barrier facilitates early closure of the defunctioning ileostomy after rectal excision: a prospective, randomized trial
    Choong Leong Tang
    Department of Colorectal Surgery, Singapore General Hospital, Singapore
    Dis Colon Rectum 46:1200-7. 2003
    A temporary loop ileostomy is often created to minimize the impact of peritoneal sepsis from an anastomotic dehiscence after a coloanal or low colorectal anastomosis...
  70. ncbi Iron supplements inhibit zinc but not copper absorption in vivo in ileostomy subjects
    Freddy J Troost
    Department of Human Biology, NUTRIM, Maastricht University, Maastricht, Netherlands
    Am J Clin Nutr 78:1018-23. 2003
    ..Iron supplements may inhibit intestinal zinc and copper uptake because these elements may compete for binding to a transporter molecule (divalent metal transporter 1) that is located on the apical side of the small intestinal epithelium...
  71. ncbi Mesh repair of parastomal hernias--a safety modification
    R J Longman
    Department of Colorectal Surgery, Gloucestershire Royal Hospital, Gloucester, UK
    Colorectal Dis 7:292-4. 2005
    ..Bowel wall erosion is a worrying potential complication of placing an edge of mesh around bowel. To reduce this possibility a simple modification is suggested...
  72. ncbi Risk factors for anastomotic failure after total mesorectal excision of rectal cancer
    K C M J Peeters
    Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands
    Br J Surg 92:211-6. 2005
    ..Anastomotic leakage is a major complication of rectal cancer surgery. The aim of this study was to investigate risk factors associated with symptomatic anastomotic leakage after total mesorectal excision (TME)...
  73. ncbi Oat bran rapidly increases bile acid excretion and bile acid synthesis: an ileostomy study
    L Ellegard
    Department of Clinical Nutrition, The Sahlgrenska Academy at the University of Göteborg, Sahlgrenska University Hospital, SE 405 30 Goteborg, Sweden
    Eur J Clin Nutr 61:938-45. 2007
    ..To study whether oat bran with native beta-glucans increases bile acid excretion and bile acid synthesis as measured by serum concentrations of 7alpha-hydroxy-4-cholesten-3-one (7alpha-HC)...
  74. doi Intervention with cloudy apple juice results in altered biological activities of ileostomy samples collected from individual volunteers
    Selvaraju Veeriah
    Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Eur J Nutr 47:226-34. 2008
    ..Apple juice is considered to be an important component of the healthy diet, with anticancer activities in colon cancer animal models and key ingredients have numerous chemoprotective activities in human colon cells in vitro...
  75. doi Intestinal diversion (colostomy or ileostomy) in patients with severe bowel dysfunction following spinal cord injury
    Barbara Hocevar
    Cleveland Clinic, Cleveland, Ohio, USA
    J Wound Ostomy Continence Nurs 35:159-66. 2008
    ..Gastrointestinal symptoms are associated with depression, anxiety, and significant impairments in quality of life (QOL) in a significant portion of persons with SCI...
  76. doi Adenocarcinoma developing at an ileostomy: report of a case and review of the literature
    Philip P Metzger
    Department of Colon and Rectal Surgery, Mayo Clinic Jacksonville, Jacksonville, Florida, USA
    Dis Colon Rectum 51:604-9. 2008
    Primary adenocarcinoma of a permanent ileostomy is a rare and unusual complication. We report a case of primary adenocarcinoma arising at an ileostomy site 46 years after total proctocolectomy for Crohn's colitis...
  77. ncbi Phytosterol and phytostanol esters are effectively hydrolysed in the gut and do not affect fat digestion in ileostomy subjects
    L Normén
    Dept of Clinical Nutrition, Goteborg University, Goteborg, Sweden
    Eur J Nutr 45:165-70. 2006
    ..Hydrolysis of phytosterol ester (PSTE) and phytostanol ester (PSTA) during fat digestion is not well characterised under controlled dietary conditions...
  78. ncbi Protective defunctioning stoma in low anterior resection for rectal carcinoma
    I Gastinger
    Institute for Quality Management in Operative Medicine at the Otto von Guericke University, Magdeburg, Germany
    Br J Surg 92:1137-42. 2005
    ..Anastomotic leak is a serious complication of resection for low rectal carcinoma...
  79. ncbi Morbidity of temporary loop ileostomy in patients with colorectal cancer
    Andreas Thalheimer
    Department of General Surgery, University of Wurzburg, Oberduerrbacherstrasse 6, 97080 Wurzburg, Germany
    Dis Colon Rectum 49:1011-7. 2006
    This study was designed to quantify the temporary loop ileostomy-related morbidity in patients with colorectal cancer and contrast the morbidity rates after ileostomy closure before, during, and after the start of adjuvant therapy.
  80. ncbi Comparison of outcomes following ileostomy versus colostomy for defunctioning colorectal anastomoses
    Henry S Tilney
    Department of Biosurgery and Surgical Technology, Imperial College London, London, UK
    World J Surg 31:1142-51. 2007
    The present study evaluated outcomes of patients undergoing proximal diversion using either a loop ileostomy or loop colostomy following distal colorectal resection for malignant and non-malignant disease.
  81. ncbi Anastomotic leak and the loop ileostomy: friend or foe?
    Traci L Hedrick
    Department of Surgery, University of Virginia Health System, Charlottesville, Virginia 22901, USA
    Dis Colon Rectum 49:1167-76. 2006
    ..This study was designed to evaluate the use of proximal diversion and surgical drainage as an alternative to anastomotic resection in the operative management of patients with anastomotic complications...
  82. ncbi Outcome of parastomal hernia repair with and without midline laparotomy
    M K Baig
    Department of Colorectal Surgery, Cleveland Clinic Florida, 2950 Cleveland Clinic Blvd, Weston, FL, USA
    Tech Coloproctol 10:282-6. 2006
    ..However, stoma relocation may require a midline laparotomy with higher associated morbidity. The aim of this study was to assess the outcome of PSH repair with relocation with or without a midline laparotomy...
  83. ncbi Subcutaneous gentamycin implant to reduce wound infections after loop-ileostomy closure: a randomized, double-blind, placebo-controlled trial
    O Haase
    Department of General, Visceral, Vascular and Thoracic Surgery, University Medicine Berlin, Berlin, Germany
    Dis Colon Rectum 48:2025-31. 2005
    After loop-ileostomy closure subcutaneous wound infection is the most frequent postoperative complication...
  84. ncbi Total laparoscopic proctocolectomy with Brooke ileostomy: a novel incisionless surgical treatment for patients with ulcerative colitis
    D W Larson
    Division of Colon and Rectal Surgery Mayo Clinic Rochester, Mayo Clinic, Gonda 9 S, 200 Fisrt Street SW, Rochester, MN 55905, USA
    Surg Endosc 19:1284-7. 2005
    ..This report describes the clinical benefits and safety of a novel (incisionless) laparoscopic operation for chronic ulcerative colitis...
  85. pmc Lymphoma in an ileostomy
    N Pranesh
    Department of Surgery, Milton Keynes General Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK
    Postgrad Med J 78:368-9. 2002
    Lymphoma developing in an ileostomy is an extremely rare complication. The presentation is similar to the commoner, yet still rare, adenocarcinoma but the staging and management of the condition differs.
  86. ncbi Will recommended changes in fat and fibre intake affect cholesterol absorption and sterol excretion? An ileostomy study
    L Ellegard
    Department of Clinical Nutrition, University of Goteborg, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Eur J Clin Nutr 54:306-13. 2000
    To study cholesterol absorption and excretion in ileostomy subjects with different intakes of saturated fat and dietary fibre.
  87. pmc Development and validation of a quality of life questionnaire for patients with colostomy or ileostomy
    Luis Prieto
    Health Qual Life Outcomes 3:62. 2005
    ..The aim of this paper is to describe the development and validation of a quality-of-life instrument, "Stoma-QOL", specifically for patients with colostomy or ileostomy.
  88. ncbi Ileal pouch-anal anastomosis, conventional ileostomy and ileorectal anastomosis modify cholesterol metabolism
    Markku J Nissinen
    Gastroenterology, Department of Medicine, University of Helsinki, Helsinki, Finland
    Dig Dis Sci 49:1444-53. 2004
    ..balance technique were analyzed in human subjects with ileal pouch-anal anastomosis (n = 34), conventional ileostomy (n = 8), ileorectostomy (n = 6), and controls (n = 29)...
  89. ncbi Promising new technique in the repair of parastomal hernia
    B M E Hansson
    Department of Surgery, University Medical Center, Nijmegen, The Netherlands
    Surg Endosc 17:1789-91. 2003
    ..The risk of infection is also minimized. The shape of the Gore-Tex mesh reduces hernia recurrence even more, prevents prolapse, and allows easy colonoscopy and stoma irrigation...
  90. ncbi What concerns subjects with inflammatory bowel disease and an ileostomy?
    E Carlsson
    Colorectal Unit, Dept of Surgery, University of Goteborg, Goteborg, Sweden
    Scand J Gastroenterol 38:978-84. 2003
    The greatest concern of patients with inflammatory bowel disease (IBD) is of having an ileostomy. The aim of this study was to describe worries and concerns in subjects with IBD and an ileostomy, and aspects of quality of life and coping ..
  91. ncbi Laparoscopically assisted colectomy and ileoanal pouch procedure with and without protective ileostomy
    P Kienle
    Surgical Department, University of Heidelberg, INF 110, 69120 Heidelberg, Germany
    Surg Endosc 17:716-20. 2003
    Apart from an obviously better cosmetic situation, there is controversy on the actual benefit of laparoscopic and laparoscopically assisted techniques in restorative proctocolectomy. The need for a protective ileostomy remains unclear.
  92. ncbi [Ileal pouch anal-anastomosis without protective ileostomy]
    Benoît Michel Gignoux
    Centre de Chirurgie Digestive, Hopital Saint Antoine, Paris, France
    Gastroenterol Clin Biol 26:671-4. 2002
    ..for ulcerative colitis (UC) or familial adenomatous polyposis (FAP) is usually associated with a defunctioning ileostomy, which may in itself cause morbidity...
  93. ncbi [Ileoanal anastomosis without ileostomy... and without laparotomy?]
    Yves Panis
    Gastroenterol Clin Biol 26:665-6. 2002
  94. ncbi Tissue-engineered colon exhibits function in vivo
    Tracy C Grikscheit
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Center for the Integration of Medicine and Innovation in Technology, Boston 02114, USA
    Surgery 132:200-4. 2002
    ..The surgical substitution of an ileal pouch for the absent colon also has a number of serious complications. We report in vivo colon replacement by tissue-engineered colon (TEC) in lieu of an ileal pouch...
  95. doi Adenocarcinoma arising from the rectal stump eleven years after excision of an ileal J-pouch in a patient with ulcerative colitis: report of a case
    Mark E Pedersen
    Department of Surgery, Odense University Hospital, Odense C, DK 5000, Denmark
    Dis Colon Rectum 51:1146-8. 2008
    ..If it is decided to remove an ileal pouch permanently, a total abdominoperineal excision should be performed, particularly in patients with risk factors for cancer development...
  96. ncbi [Surgical strategies in patients with inflammatory bowel disease]
    M Von Flue
    Chirurgische Klinik A, Kantonsspital Luzern, Luzern
    Ther Umsch 60:165-73. 2003
    ..Best profit for those patients are treatment with an interdisciplinary team, consisting of gastroenterologists, nutrition advisers, psychologists, surgeons and radiologists...
  97. ncbi [Surgical approach is toxic colitis]
    K H Vestweber
    Klinikum Leverkusen, Dhunnberg 60, 51375 Leverkusen
    Kongressbd Dtsch Ges Chir Kongr 119:67-72. 2002
    ..option for toxic colitis usually is subtotal colectomy with closure of the rectal stump or mucus fistula and ileostomy. This procedure allows the reconstructive operation later on...
  98. ncbi [Acute cytomegalovirus colitis after bone marrow transplantation]
    Mohamed Aziz Hani
    Service de Chirurgie Beau Séjour, Hopital Charles Nicolle, Tunis, Tunisie
    Tunis Med 81:145-8. 2003
    ..An emergency subtotal colectomy with sigmoidostomy and ileostomy was performed followed six weeks later by an ileorectal anastomosis...
  99. ncbi A prospective audit of stomas--analysis of risk factors and complications and their management
    P J Arumugam
    Colorectal Unit, Singleton Hospital, Sketty, Swansea SA2 8QA, UK
    Colorectal Dis 5:49-52. 2003
    ..To prospectively audit stomas and to determine the nature and rate of complications and their relationship with various risk factors and their management...
  100. ncbi The interrupted serosubmucosal anastomosis - still the gold standard
    A Leslie
    Department of Surgery and Molecular Oncology, University of Dundee, Dundee, UK
    Colorectal Dis 5:362-6. 2003
    ..This report describes the results of these operations, the results of stapled anastomoses carried out during the same period and discusses the utility of the handsewn technique...
  101. ncbi A defunctioning stoma in the treatment of lower third rectal carcinoma
    D Giuliani
    Department of General and Abdominal Surgery, ZNA Middelheim, Antwerp, Belgium
    Acta Chir Belg 106:40-3. 2006
    ..On top of this, many patients will receive neo-adjuvant radio-chemotherapy. A defunctioning stoma helps in avoiding severe complications of anastomotic failure...

Research Grants66

  1. Acupuncture to Prevent Postoperative Paralytic lleus
    JOSEPH CHIANG; Fiscal Year: 2004
    ..is effective in preventing postoperative paralytic ileus (PPI) among cancer survivors undergoing colostomy/ileostomy closure...
  2. Smart Seal Ostomy Appliance
    JEFFREY SCHOESS; Fiscal Year: 2005
    ..The pressing need to provide effective skin barriers for colostomy, ileostomy and urostomy patients, achieving an effective appliance seal is critical to physical and emotional well-being as ..
  3. Smart Seal Ostomy Appliance
    JEFFREY SCHOESS; Fiscal Year: 2006
    ..The pressing need to provide effective skin barriers for colostomy, ileostomy and urostomy patients, achieving an effective appliance seal is critical to physical and emotional well-being as ..
  4. HR-QOL in Colorectal Cancer Survivors with Stomas
    Robert Krouse; Fiscal Year: 2006
    ..The final step will be to convene provider investigators to make recommendations for future interventions and dissemination methods based upon study findings. ..
  5. HR-QOL in Colorectal Cancer Survivors with Stomas
    ROBERT S contact KROUSE; Fiscal Year: 2010
    ....
  6. Pilot study on the safety and efficacy of ciprofloxacin for prophylactic preventi
    Hans Herfarth; Fiscal Year: 2007
    ..therapy with either metronidazole or ornidazole or the absence of inflammation in patients with diverting ileostomy. However, both aforementioned antibiotic regimens have numerous adverse events limiting the value of this ..
  7. Smart Seal Ostomy Appliance
    JEFFREY SCHOESS; Fiscal Year: 2002
    ..Effective seals for colostomy, ileostomy and urostomy, are critical to physical and emotional well-being as well as functional abilities of an individual ..
  8. HR-QOL in Colorectal Cancer Survivors with Stomas
    Robert Krouse; Fiscal Year: 2009
    ....
  9. IKSI: 1st Annual International Urolithiasis Research Symposium
    Andrew Evan; Fiscal Year: 2007
    ....
  10. Risk for Renal Injury Caused by Shock Wave Lithotripsy
    Andrew Evan; Fiscal Year: 2007
    ..All of these proposed studies aim at understanding the adverse effects of shock waves and advancing the safety of all stone patients at a time when reports of adverse effects in SWL are on the rise. ..
  11. TEM with Digital and Cryopreparation Systems
    Andrew Evan; Fiscal Year: 2003
    ..Dr. Richard Gregory will employ immunohistochemistry to examine the role of a Streptococcus mutans 65 kDa fimbrial protein binding as a mechanism for the induction of dental carries. ..
  12. International Conference on Malignant Bowel Obstruction
    Robert Krouse; Fiscal Year: 2004
    ..Using MBO as a model, a consensus will be attained for methodological approaches and the implementation of palliative care research. ..
  13. Gastric Injury In Trauma and Surgical Sepsis
    David Soybel; Fiscal Year: 2009
    ..Such therapeutic strategies would be applicable not only to injury in the stomach, but to other regions of the GI tract affected by systemic stress and acute inflammation. ..
  14. Gastric Injury In Trauma and Surgical Sepsis
    David Soybel; Fiscal Year: 2007
    ..Such therapeutic strategies would be applicable not only to injury in the stomach, but to other regions of the GI tract affected bysystemic stress and acute inflammation. ..
  15. Clinical Approaches to Ileal Pouch Dysfunction
    Bo Shen; Fiscal Year: 2005
    ..The AIMS of study are to 1) investigate visceral hypersensitivity using barostat examination of the pouch; 2) conduct a randomized, placebo-controlled clinical trial evaluating the use of amitriptyline in IPS. ..
  16. Radiation-Induced Heart Disease: Mechanisms and Interventions
    Marjan Boerma; Fiscal Year: 2010
    ....
  17. FLAVONOID BIOAVAILABILITY IN HUMANS-CELLULAR STUDIES
    Thomas Walle; Fiscal Year: 2005
    ..The findings from the proposed studies should help us understand the bioavailability of the flavonoids, facilitating optimization of the chemopreventive utility of these natural or synthetic compounds. ..
  18. H+ NEUTRALIZATION AND C1- HOMEOSTASIS IN GASTRIC MUCOSA
    David Soybel; Fiscal Year: 2002
    ....
  19. FLAVONOID BIOAVAILABILITY IN HUMANS--CELLULAR STUDIES
    Thomas Walle; Fiscal Year: 2002
    ..In these studies we will in first hand seek to determine the bioavailability of flavonoid glycosides and their subsequent hydrolysis to aglycones in normal volunteers through plasma and urine determinations. ..
  20. Racial Disparities in Inflammatory Bowel Disease
    GEOFFREY NGUYEN; Fiscal Year: 2006
    ..Establishing the presence of IBD health disparities and understanding their mechanisms will facilitate interventions in public policy and education to optimize health care utilization and outcomes in underserved populations. ..
  21. RESEARCH TRAINING IN ALIMENTARY TRACT SURGERY
    David Soybel; Fiscal Year: 2007
    ..A pro-active process for seeking applications from individuals belonging to under-represented minority groups is coordinated through the Offices for Diversity at HMS and each of the participating institutions. ..
  22. US VALUATION OF THE EUROQOL EQ-5D HEALTH STATES
    Stephen Coons; Fiscal Year: 2002
    ....
  23. ANDROGEN RECEPTOR REGULATION OF PROSTATE CANCER GROWTH
    Samir Taneja; Fiscal Year: 2002
    ....
  24. Gastric Injury In Trauma and Surgical Sepsis
    David I Soybel; Fiscal Year: 2010
    ..Such therapeutic strategies would be applicable not only to injury in the stomach, but to other regions of the GI tract affected by systemic stress and acute inflammation. ..