Genomes and Genes
Summary: Endoscopic examination, therapy or surgery of the esophagus.
Publications215 found, 100 shown here
- Endoscopic therapy for esophageal perforation or anastomotic leak with a self-expandable metallic stentJessica M Leers
Department of General, Visceral and Cancer Surgery, University of Cologne, Kerpener Strasse 62, 50937, Koln, Germany
Surg Endosc 23:2258-62. 2009..Therapeutic options are surgical repair or resection or conservative management with cessation of oral intake and antibiotic therapy. We evaluated an alternative approach that uses self-expandable metallic stents (SEMS)...
- Treatment of thoracic esophageal anastomotic leaks and esophageal perforations with endoluminal stents: efficacy and current limitationsDirk Tuebergen
Department of General Surgery, Unit of Surgical Endoscopy, University of Muenster, Muenster, Germany
J Gastrointest Surg 12:1168-76. 2008..The objective of this non-randomized observational study was to evaluate the effects of endoluminal stent treatment in patients with esophageal anastomotic leakages or perforations in a single tertiary care center...
- Clinicopathological factors associated with clinical outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasmsH Isomoto
Department of Endoscopy, Nagasaki University Hospital, Sakamoto, Nagasaki, Japan
Endoscopy 41:679-83. 2009..We sought to unravel the clinicopathological factors associated with the clinical outcomes of ESD for colorectal epithelial neoplasms in a large series...
- Pediatric caustic ingestion: 50 consecutive cases and a review of the literatureF Riffat
Department of Otolaryngology, Children s Hospital Westmead, Westmead NSW, Australia
Dis Esophagus 22:89-94. 2009..retrospective case note review of all admissions to the otolaryngology unit with caustic injury that underwent esophagoscopy to the Children's Hospital Westmead between 1990 and 2007...
- Use of self-expandable metal stents for the treatment of esophageal perforations and anastomotic leaksP Salminen
Department of Surgery, Turku University Central Hospital, Turku, Finland
Surg Endosc 23:1526-30. 2009..This study aimed to evaluate the role of covered SEMS for the management of esophageal perforations and anastomotic leaks...
- Esophageal stent placement for the treatment of spontaneous esophageal perforationsRichard K Freeman
Department of Thoracic and Cardiovascular Surgery, St Vincent Hospital, Indianapolis, Indiana, USA
Ann Thorac Surg 88:194-8. 2009..Traditional therapy for spontaneous esophageal perforation has most often been urgent operative repair. This investigation summarizes the treatment of spontaneous perforations of the esophagus using an occlusive removable esophageal stent...
- Esophageal stent placement for the treatment of iatrogenic intrathoracic esophageal perforationRichard K Freeman
Department of Thoracic and Cardiovascular Surgery, St Vincent Hospital, Indianapolis, Indiana, USA
Ann Thorac Surg 83:2003-7; discussion 2007-8. 2007..This investigation summarizes our experiences treating iatrogenic intrathoracic perforations of the esophagus using an occlusive removable esophageal stent...
- Endoscopic clips for closing esophageal perforations: case report and pooled analysisMohammed A Qadeer
Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio 44195, USA
Gastrointest Endosc 66:605-11. 2007..Acute and chronic esophageal perforations have traditionally been treated with surgery or a conservative approach. Recently, endoscopic repair has been reported in some case reports...
- Treatment of oesophageal ulcerations using endoscopic transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets in a canine modelT Ohki
Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan
Gut 55:1704-10. 2006....
- Endoscopic submucosal dissection of early esophageal cancerTsuneo Oyama
Department of Gastroenterology, Saku General Hospital, Nagano, Japan
Clin Gastroenterol Hepatol 3:S67-70. 2005..Endoscopic submucosal dissection with the hook knife is a method of endoluminal surgery enabling large en bloc resections without increased surgical risks...
- Circumferential EMR and complete removal of Barrett's epithelium: a new approach to management of Barrett's esophagus containing high-grade intraepithelial neoplasia and intramucosal carcinomaStefan Seewald
Department of Interdisciplinary Endoscopy, University Hospital Hamburg-Eppendorf, Germany
Gastrointest Endosc 57:854-9. 2003..CONCLUSIONS: Circumferential EMR with a simple snare technique is feasible, safe, and effective for complete removal of Barrett's epithelium with early stage malignant changes...
- Stent-in-stent technique for removal of embedded esophageal self-expanding metal stentsM M C Hirdes
Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands
Am J Gastroenterol 106:286-93. 2011..Our aim is to report the results of removal of embedded, partially covered SEMSs by induction of pressure necrosis using the stent-in-stent technique...
- Postoperative esophageal leak management with the Polyflex esophageal stentRichard K Freeman
Department of Thoracic and Cardiovascular Surgery, St Vincent Hospital, Indianapolis, Ind, USA
J Thorac Cardiovasc Surg 133:333-8. 2007..This investigation reviews our experience treating postoperative esophageal leaks with the Polyflex esophageal stent (Boston Scientific, Natick, Mass)...
- Effect of the GABA(B) agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitorsG H Koek
Center for Gastroenterological Research, University Hospital Gasthuisberg, Leuven, Belgium
Gut 52:1397-402. 2003..7) to 5.8 (1.3) (p<0.01). Four patients reported mild side effects of nausea or drowsiness. CONCLUSIONS: The GABA(B) receptor agonist baclofen improves duodenal reflux and associated reflux symptoms that persist during PPI therapy...
- Balloon-based, circumferential, endoscopic radiofrequency ablation of Barrett's esophagus: 1-year follow-up of 100 patientsVirender K Sharma
Division of Gastroenterology and Hepatology, Mayo Clinic Scottsdale Phoenix, Scottsdale, Arizona, USA
Gastrointest Endosc 65:185-95. 2007..To assess the dose-response, safety, and efficacy of circumferential endoscopic ablation of Barrett's esophagus (BE) by using an endoscopic balloon-based ablation device (HALO360 System)...
- Esophageal foreign bodies in the pediatric population: our first 500 casesDanny C Little
Department of Surgery, Children's Mercy Hospital, Kansas City, MO 64108, USA
J Pediatr Surg 41:914-8. 2006..Historically, rigid esophagoscopy with extraction of the foreign body has been the recommended treatment...
- Treatment of esophageal perforations and anastomotic leaks: the endoscopist is stepping into the arenaPeter D Siersema
Gastrointest Endosc 61:897-900. 2005
- Endoscopic vacuum sponge therapy for esophageal defectsGunnar Loske
Department for General, Abdominal, Thoracic and Vascular Surgery, Katholisches Marienkrankenhaus Hamburg gGmbH, Alfredstrasse 9, 22087, Hamburg, Germany
Surg Endosc 24:2531-5. 2010..For anastomotic insufficiency in the rectum, endoscopic vacuum therapy has already been used successfully. The authors used vacuum therapy for anastomotic defects and other lesions of the esophagus...
- Aetiology, treatment and mortality after oesophageal perforation in DenmarkPhilip Ryom
Thoracic Surgery Department, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark
Dan Med Bull 58:A4267. 2011..The causes are numerous. Treatment for oesophageal perforation targets mediastinal and pleural contamination. Present knowledge about the causes of perforation and the types of treatment is poor...
- Esophagogastroduodenoscopy-associated gastrointestinal perforations: a single-center experienceAmit Merchea
Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
Surgery 148:876-80; discussion 881-2. 2010..Our aim was to define the risk of perforation associated with EGD and identify patients who required operative intervention...
- Esophageal perforation: surgical, endoscopic and medical management strategiesBoris Sepesi
Division of Thoracic and Foregut Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, New York 14642, USA
Curr Opin Gastroenterol 26:379-83. 2010..The relative rarity and unpredictability of esophageal perforation has precluded a randomized or multiinstitutional study of this condition. Practice standards are based primarily on retrospective reviews and expert opinions...
- Current management of esophageal perforation: 20 years experienceA Eroglu
Ataturk University, Medical Faculty, Department of Thoracic Surgery, Erzurum, Turkey
Dis Esophagus 22:374-80. 2009..We suggest that minimally invasive techniques for the repair of esophageal perforations will be very important in the future treatment of this condition...
- Herpes simplex virus esophagitis in immunocompetent childrenFernanda Rodrigues
Hospital Pediátrico de Coimbra, Portugal
J Pediatr Gastroenterol Nutr 39:560-3. 2004..To review clinical, laboratory, endoscopic and histologic features, treatment and outcome of immunocompetent children with Herpes simplex virus esophagitis...
- Management of esophageal perforations: the value of aggressive surgical treatmentJ David Richardson
Department of Surgery, University of Louisville School of Medicine, Louisville, KY 40292, USA
Am J Surg 190:161-5. 2005..The treatment of esophageal perforation remains controversial, particularly in terms of the type of operative therapy. This report analyzed results of an aggressive treatment protocol...
- Repair of esophageal perforation due to anterior cervical spine instrumentationRyan L Kau
Division of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Scottsdale, Arizona, USA
Laryngoscope 120:739-42. 2010..Postoperatively, both patients had no evidence of persistent perforation and had resolution of preoperative symptoms...
- Current concepts in the management of esophageal perforations: a twenty-seven year Canadian experiencePankaj Bhatia
Division of Thoracic Surgery, The University of Western Ontario, London, Ontario, Canada
Ann Thorac Surg 92:209-15. 2011..Perforation of the esophagus remains a challenging clinical problem...
- Predictors of postoperative stricture after esophageal endoscopic submucosal dissection for superficial squamous cell neoplasmsS Ono
Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo, Japan
Endoscopy 41:661-5. 2009..Although endoscopic submucosal dissection (ESD) is becoming accepted as an established treatment for superficial esophageal squamous cell neoplasms, the risks for developing postoperative stricture have not been elucidated...
- Successful treatment of severe refractory anastomotic stricture in an infant after esophageal atresia repair by endoscopic balloon dilation combined with systemic administration of dexamethasoneTomoro Hishiki
Department of Pediatric Surgery, Chiba University Hospital, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba, 260 8677, Japan
Pediatr Surg Int 25:531-3. 2009..Balloon dilation in combination with systemic dexamethasone administration may be an effective treatment that could substitute invasive techniques including surgical manipulation for severe refractory strictures...
- Flexible esophagoscopy as a diagnostic tool for traumatic esophageal injuriesVitor Arantes
Endoscopy Unit, Emergency Hospital João XXIII, FHEMIG, Belo Horizonte, Minas Gerais, Brazil
J Trauma 66:1677-82. 2009..This study aimed to assess the yield and clinical utility of flexible esophagoscopy (FE) in the diagnosis of traumatic esophageal injuries.
- Patient tolerance and acceptance of unsedated ultrathin esophagoscopyAshley L Faulx
Division of Gastroenterology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA
Gastrointest Endosc 55:620-3. 2002..METHODS: Outpatients referred for standard EGD were recruited to undergo unsedated ultrathin esophagoscopy (UUE) with a new 3.1-mm battery-powered esophagoscope before sedated EGD...
- Endoscopic treatment of thoracic esophageal anastomotic leaks by using silicone-covered, self-expanding polyester stentsDaniel Schubert
Department of General, Visceral and Vascular Surgery, Faculty of Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany
Gastrointest Endosc 61:891-6. 2005..CONCLUSIONS: The placement of silicone-covered self-expanding polyester stents seems to be a successful minimally invasive treatment option for clinically apparent intrathoracic esophageal anastomotic leaks...
- Management of esophageal foreign bodies: a retrospective review of 400 casesKalliopi Athanassiadi
Department of Thoracic Surgery, General Hospital of Nikea, Piraeus, Greece
Eur J Cardiothorac Surg 21:653-6. 2002..A retrospective study was conducted in 400 patients with esophageal foreign bodies (EFB) to assess characteristics of EFB and methods of treatment...
- Histological precursors of oesophageal squamous cell carcinoma: results from a 13 year prospective follow up study in a high risk populationG-Q Wang
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, 6116 Executive Boulevard, Suite 705, Bethesda, MD 20892-8314, USA
Gut 54:187-92. 2005..Documenting these precursor lesions of OSCC should assist in the development of effective prevention, early detection, and treatment strategies for this disease...
- Impact of a self-expanding, plastic esophageal stent on various esophageal stenoses, fistulas, and leakages: a single-center experience in 39 patientsKlaus Radecke
Department of Gastroenterology and Hepatology, University of Duisberg Essen, Essen, Germany
Gastrointest Endosc 61:812-8. 2005..The majority of placements were difficult to treat situations, i.e., proximal or extremely proximal stent release or emergency cases in the intensive care unit...
- Endoscopic survey of esophageal cancer in a high-risk area of ChinaXu-Jing Lu
Hebei Cancer Institute, Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang 050011, Hebei Province, China
World J Gastroenterol 10:2931-5. 2004....
- Risk factors for oesophageal squamous dysplasia in adult inhabitants of a high risk region of ChinaW-Q Wei
Cancer Prevention Studies Branch, 6116 Executive Blvd, Rm 705, Bethesda, MD 20892-8314, USA
Gut 54:759-63. 2005..The final model did a poor job of identifying subjects who had squamous dysplasia. Other methods will need to be developed to triage individuals to endoscopy in this high risk population...
- Surgical treatment of esophageal high-grade dysplasiaMichael F Reed
Division of Thoracic Surgery, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
Ann Thorac Surg 79:1110-5; discussion 1110-5. 2005..A significant percentage with an initial diagnosis of HGD will have invasive disease at resection. Surgery is the optimal treatment for HGD unless contraindicated by severe comorbidities...
- A randomised controlled trial of ablation of Barrett's oesophagus with multipolar electrocoagulation versus argon plasma coagulation in combination with acid suppression: long term resultsP Sharma
University of Kansas School of Medicine and Veterans Affairs Medical Center, Kansas City, MO 64128 2295, USA
Gut 55:1233-9. 2006..Many modalities have been used to ablate Barrett's oesophagus (BO). However, long term results and comparative effectiveness are unknown...
- The long-term efficacy of pneumatic dilatation and Heller myotomy for the treatment of achalasiaMarcelo F Vela
Department of Gastroenterology, Center for Swallowing and Esophageal Disorders, The Cleveland Clinic Foundation, Cleaveland, Ohio, USA
Clin Gastroenterol Hepatol 4:580-7. 2006..CONCLUSIONS: No treatment cures achalasia. Short- and long-term success is similar for graded PD and laparoscopic HM. Therapeutic success decreases steadily over time. Achalasia patients need careful long-term follow-up evaluation...
- Photodynamic therapy with m-tetrahydroxyphenyl chlorin for high-grade dysplasia and early cancer in Barrett's columnar lined esophagusLaurence B Lovat
National Medical Laser Centre, Department of Surgery, Royal Free and University College Medical School, London, United Kingdom
Gastrointest Endosc 62:617-23. 2005..Red light via a diffuser device appears to be the most effective light-delivery technique. Biopsy specimens should not be taken for at least 2 months after treatment...
- Risk factors for erosive esophagitis: a multivariate analysis based on the ProGERD study initiativeJoachim Labenz
Department of Medicine, Jung-Stilling Hospital, Wichernstrasse 40, 57074 Siegen, Germany
Am J Gastroenterol 99:1652-6. 2004..Thus, endoscopy is still required in all GERD patients if valid information on the state of the esophageal mucosa is needed...
- Ultrathin esophagoscopy in screening for Barrett's esophagus at a Veterans Administration Hospital: easy access does not lead to referralsMatt Atkinson
Case Western Reserve University, Cleveland, Ohio, USA
Am J Gastroenterol 103:92-7. 2008Unsedated, ultrathin esophagoscopy has been shown to be tolerable, safe, and accurate. Survey data have suggested that accessibility of unsedated esophagoscopy would increase referrals for Barrett's esophagus (BE) screening...
- Wireless pH testing as an adjunct to unsedated transnasal esophagoscopy: the safety and efficacy of transnasal telemetry capsule placementPeter C Belafsky
Scripps Center for Voice and Swollowing, La Jola, CA 92037, USA
Otolaryngol Head Neck Surg 131:26-8. 2004..The success of transnasal wireless pH capsule placement has not been previously described. The purpose of this investigation was to describe our experience with transnasal wireless pH capsule placement...
- 5-aminolevulinic acid photodynamic therapy versus argon plasma coagulation for ablation of Barrett's oesophagus: a randomised trialM Hage
Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre Rotterdam, The Netherlands
Gut 53:785-90. 2004..As the goal of treatment should be complete reversal of Barrett's epithelium, we do not recommend these techniques for the prophylactic ablation of BO...
- High-energy laser therapy of Barrett's esophagus: preliminary resultsLorenzo Norberto
Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Clinica Chirurgica Generale I, Universita di Padova, Via Giustiniani 2, 35128 Padua, Italy
World J Surg 28:350-4. 2004..Further studies are necessary to quantify its effect on cancer incidence...
- Oesophagectomy remains the gold standard for treatment of high-grade dysplasia in Barrett's oesophagusVijay Sujendran
Department of Upper GI Surgery and Pathology, The John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
Eur J Cardiothorac Surg 28:763-6. 2005..To re-examine the role of oesophagectomy we looked at the incidence of invasive cancer in patients undergoing resection for HGD and their subsequent outcome...
- Clinical experience of patients undergoing photodynamic therapy for Barrett's dysplasia or cancerH C Wolfsen
Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL 32224, USA
Aliment Pharmacol Ther 20:1125-31. 2004..Photodynamic therapy using porfimer sodium is the only approved endoscopic treatment for use in patients with Barrett's high-grade dysplasia...
- Primary care physician attitudes toward endoscopic screening for GERD symptoms and unsedated esophagoscopyVikram Boolchand
Department of Medicine, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio, USA
Gastrointest Endosc 63:228-33. 2006..Unsedated esophagoscopy (UE) is a less costly alternative to standard EGD for identifying BE...
- Normalization of oesophageal pH does not guarantee control of duodenogastro-oesophageal reflux in Barrett's oesophagusJ A Todd
Digestive Diseases Centre, University Hospitals of Leicester NHS Trust, Gwendolen Road, Leicester LE5 4PW, UK
Aliment Pharmacol Ther 21:969-75. 2005..Of the 20 patients who had a normal 24 h oesophageal pH profile, 11 (55%) had pathological exposure to bile in their oesophagus. CONCLUSION: Complete acid suppression does not guarantee elimination of duodenogastro-oesophageal reflux...
- Ablation of nonneoplastic Barrett's mucosa using argon plasma coagulation with concomitant esomeprazole therapy (APBANEX): a prospective multicenter evaluationHendrik Manner
Department of Internal Medicine II, HSK Wiesbaden, Wiesbaden, Germany
Am J Gastroenterol 101:1762-9. 2006..However, APC has a relevant morbidity. Therefore, ablation of nonneoplastic BE cannot be recommended generally because incidence of cancer in BE is low...
- Transnasal esophagoscopy: revisited (over 700 consecutive cases)Gregory N Postma
Department of Otolaryngology Head and Neck Surgery, Center for Voice and Swallowing Disorders of Wake Forest University, Winston Salem, North Carolina 27157 1034, USA
Laryngoscope 115:321-3. 2005High-resolution transnasal esophagoscopy (TNE) allows comprehensive, in-office examination of the esophagus without sedation.
- Poor results of 5-aminolevulinic acid-photodynamic therapy for residual high-grade dysplasia and early cancer in barrett esophagus after endoscopic resectionF Peters
Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, Netherlands
Endoscopy 37:418-24. 2005..Most patients undergoing 5-ALA-PDT have residual Barrett mucosa after PDT and 5-ALA-PDT does not seem to prevent recurrences during follow-up...
- Barrett's esophagus--Who, how, how often and what to do with dysplasia?Lawrence C Hookey
Division of Gastroenterology, Hotel Dieu Hospital, Kingston, Canada
Can J Gastroenterol 20:463-6. 2006
- Endoscopic ablation of dysplastic Barrett's oesophagus comparing argon plasma coagulation and photodynamic therapy: a randomized prospective trial assessing efficacy and cost-effectivenessKrish Ragunath
Department of Gastroenterology, University Hospital Aintree, Liverpool, UK
Scand J Gastroenterol 40:750-8. 2005..The purpose of this study was to investigate the efficacy and cost-effectiveness of two promising techniques, argon plasma coagulation (APC) and photodynamic therapy (PDT), in the ablation of dysplastic Barrett's oesophagus...
- Recent developments in the pathophysiology and therapy of gastroesophageal reflux disease and nonerosive reflux diseaseJan Tack
Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
Curr Opin Gastroenterol 21:454-60. 2005..This review summarizes recent progress in our understanding of the pathophysiology and treatment of gastroesophageal reflux disease...
- Endoscopic ablation of Barrett's oesophagus: a randomized-controlled trial of photodynamic therapy vs. argon plasma coagulationC J Kelty
Academic Surgical Oncology Unit, University of Sheffield, Sheffield, UK
Aliment Pharmacol Ther 20:1289-96. 2004..5-Aminlevulinic acid-induced photodynamic therapy and argon plasma coagulation have been shown to be effective for ablating Barrett's oesophagus, but a comparative trial of these two modalities has not been reported...
- Cost-effectiveness of aspirin chemoprevention for Barrett's esophagusChin Hur
Gastrointestinal Unit and The Institute for Technology Assessment, Massachusetts General Hospital, Boston, USA
J Natl Cancer Inst 96:316-25. 2004..We used a modeling approach to determine and compare the effectiveness and cost-effectiveness of aspirin with and without endoscopic surveillance to prevent esophageal adenocarcinoma...
- Endoscopic endoluminal radiofrequency ablation of Barrett's esophagus in patients with fundoplicationsN Hubbard
Division of General Surgery, K 8, Henry Ford Hospital, 2799 West Grand Blvd, Detroit, Michigan 48202 2689, USA
Surg Endosc 21:625-8. 2007..This report is presents an early experience of the effects of endoluminal ablation on the reflux symptoms and completeness of ablation in post-fundoplication patients...
- Long-term survival following endoscopic and surgical treatment of high-grade dysplasia in Barrett's esophagusGanapathy A Prasad
Barrett s Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Gastroenterology 132:1226-33. 2007..Critical information regarding overall survival of patients followed up long-term after these therapies is lacking. Our aim was to compare the long-term survival of patients treated with PDT with patients treated with esophagectomy...
- Argon plasma coagulation in the treatment of Barrett's high-grade dysplasia and in situ adenocarcinomaJ L Van Laethem
Dept of Gastroenterology, Erasme University Hospital, Brussels, Belgium
Endoscopy 33:257-61. 2001..We report our initial experience in the application of APC in this indication...
- Eradication of Barrett esophagus with early neoplasia by radiofrequency ablation, with or without endoscopic resectionRoos E Pouw
Department of Gastroenterology and Hepatology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
J Gastrointest Surg 12:1627-36; discussion 1636-7. 2008..The aim was to report the combined results of two published and two ongoing studies on radiofrequency ablation of BE with early neoplasia, as presented at SSAT presidential plenary session DDW 2008...
- Prevalence of endoscopic findings of erosive esophagitis in children: a population-based studyMark A Gilger
Department of Pediatrics, Baylor College of Medicine, Houston Center for Quality of Care and Utilization Studies, Veterans Administration Hospital, Houston, TX, USA
J Pediatr Gastroenterol Nutr 47:141-6. 2008..The prevalence of such GERD complications in children is unknown. The purpose of this study was to determine the prevalence of endoscopic findings of erosive esophagitis in children...
- Endoscopic ablation of Barrett's esophagus: a multicenter study with 2.5-year follow-upDavid E Fleischer
Mayo Clinic, Scottsdale, Arizona 85259, USA
Gastrointest Endosc 68:867-76. 2008..Various endoscopic therapies have been used to eradicate BE. Recently circumferential radiofrequency ablation has been used with encouraging short-term results...
- Circumferential ablation of Barrett's esophagus that contains high-grade dysplasia: a U.S. Multicenter RegistryRobert A Ganz
Minnesota Gastroenterology, Plymouth, Minnesota 55446, USA
Gastrointest Endosc 68:35-40. 2008..The management strategies for Barrett's esophagus (BE) that contains high-grade dysplasia (HGD) include intensive endoscopic surveillance, photodynamic therapy, thermal ablation, EMR, and esophagectomy...
- Low reproducibility of 2 x 24-hour continuous esophageal pH monitoring in infants and children: a limiting factor for interventional studiesRasmus Gaardskaer Nielsen
Pediatric Department, Odense University Hospital, University of Southern Denmark, Odense C, Denmark
Dig Dis Sci 48:1495-502. 2003..The day-to-day variability limits the use of simultaneous pH monitoring and dietary challenges as a procedure to identify a possible causative relation between GERD and dietary allergy/intolerance...
- Self-administered symptom questionnaires in patients with dyspepsia and their yield in discriminating between endoscopic diagnosesE Bolling-Sternevald
Department of Biomedicine, Linköping Hospital, Linkoping, Sweden
Dig Dis 20:191-8. 2002..We aimed at evaluating whether specific gastrointestinal symptoms, identified by self-administered questionnaires, correlate with specific endoscopic diagnoses and discriminate organic from functional dyspepsia...
- Eradication of dysplastic Barrett's oesophagus using photodynamic therapy: long-term follow-upR Ackroyd
Department of Surgery, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK
Endoscopy 35:496-501. 2003..We present the results of long-term follow-up of its efficacy in patients with dysplastic Barrett's oesophagus...
- Updated guidelines for the diagnosis, surveillance, and therapy of Barrett's esophagusRichard E Sampliner
Southern Arizona VA Health Care System, Tucson 85723, USA
Am J Gastroenterol 97:1888-95. 2002
- Outcomes of dysplasia arising in Barrett's esophagus: a dynamic viewRenato Romagnoli
Upper G-I Surgery Unit, Louvain Medical School, Brussels, Belgium
J Am Coll Surg 197:365-71. 2003..Not enrolling a patient with LGD in an endoscopic surveillance program can lead to the development of extramural IC with poor outcomes...
- Radiofrequency ablation of Barrett's esophagus: short-term resultsShady M Eldaif
Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA
Ann Thorac Surg 87:405-10; discussion 410-1. 2009..This study evaluated the early results of a balloon-based catheter radiofrequency ablation (RFA) system in patients with medically refractory reflux symptoms and biopsy-proven BE...
- Diagnostic modalities for achalasiaS Gonlachanvit
Gastroenterology Section, Department of Internal Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
Gastrointest Endosc Clin N Am 11:293-310, vi. 2001..The article reviews these and other diagnostic tests that may be used in evaluating patients suspected of having achalasia...
- Combination of endoscopic argon plasma coagulation and antireflux surgery for treatment of Barrett's esophagusH Tigges
University of Wuerzburg, Germany
J Gastrointest Surg 5:251-9. 2001..Long-term follow-up of this therapy is necessary to evaluate its effect on cancer risk in Barrett's esophagus...
- Predictors of recurrent specialized intestinal metaplasia after complete laser ablationRobert S Fisher
Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
Am J Gastroenterol 98:1945-51. 2003..Laser ablation of Barrett's epithelium is an investigational intervention that should be restricted to research protocols...
- Endoscopic endoluminal radiofrequency ablation of Barrett's esophagus: initial results and lessons learnedVic Velanovich
Division of General Surgery, K 8, Henry Ford Hospital, 2799 West Grand Blvd, Detroit, MI 48202 2689, USA
Surg Endosc 23:2175-80. 2009..This study reports the experience of a single surgeon using an endoscopic endoluminal device that delivers radiofrequency energy (the BARRx device) to ablate Barrett's esophagus...
- Effect of multipolar electrocoagulation on EUS findings in Barrett's esophagusDouglas O Faigel
Portland VA Medical Center, Oregon Health and Science University, Portland, Oregon, 97201, USA
Gastrointest Endosc 55:23-6. 2002..A decrease in wall thickness by EUS was associated with the absence of intestinal metaplasia in follow-up biopsy specimens...
- Endoscopic manifestations of gastroesophageal reflux disease in patients between 18 months and 25 years without neurological deficitsHashem B El-Serag
Section of Gastroenterology at the Houston Veterans Affairs Medical Center, Texas 77030, USA
Am J Gastroenterol 97:1635-9. 2002..Further studies are needed to examine the future subsequent clinical course of these children. On the other hand, BE was absent making it likely that the duration of reflux is a major risk factor for BE...
- Long-term endoscopic surveillance of patients with Barrett's esophagus. Incidence of dysplasia and adenocarcinoma: a prospective studyMassimo Conio
Department of Gastroenterology, National Institute for Cancer Research, Genova, Italy
Am J Gastroenterol 98:1931-9. 2003..In our patient cohort, surveillance involved a large expenditure of effort but did not prevent any cancer deaths. The benefit of surveillance remains uncertain...
- Endoscopic submucosal dissection of esophageal squamous cell neoplasmsMitsuhiro Fujishiro
Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Clin Gastroenterol Hepatol 4:688-94. 2006..Application of the technique is desirable for esophageal squamous cell neoplasms (SCNs), but there have been no reports on the use of this procedure in the esophagus...
- A novel technique of concurrent esophagoscopy and transgastrostomy gastroscopy to dilate a completely obstructed distal esophageal stricture in a child following fundoplicationJ H Isaiah
General Pediatrics, University of Alberta, Edmonton, Canada
Endoscopy 37:776-8. 2005..Barium studies and esophagoscopy had revealed complete obstruction of the lower esophagus...
- Patient preferences for the management of high-grade dysplasia in Barrett's esophagusChin Hur
Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
Dig Dis Sci 50:116-25. 2005..In summary, when patients with Barrett's esophagus were presented with three options to manage HGD, the majority chose endoscopic surveillance. Familiarity with endoscopic surveillance was the predominant reason for the choice...
- Is same-day discharge suitable following rigid esophagoscopy? Findings in a series of 655 casesHaytham Kubba
Department of Otolaryngology, Crosshouse Hospital, Kilmarnock, Scotland
Ear Nose Throat J 82:33-6. 2003..Our aims were to establish the minimum duration of postoperative observation that is required following esophagoscopy and to propose criteria for safe same-day discharge. We found that perforation rates were 4...
- En bloc resection of a large semicircular esophageal cancer by endoscopic submucosal dissectionMitsuhiro Fujishiro
Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, Tokyo
Surg Laparosc Endosc Percutan Tech 16:237-41. 2006..Six months after ESD, mild stenosis remained, but dilation was no longer needed, and esophagogastroduodenoscopy with chromoendoscopy and biopsy revealed no residual or recurrent cancer...
- Distinct clinical characteristics between patients with nonerosive reflux disease and those with reflux esophagitisJustin C Y Wu
Institute of Digestive Disease, The Chinese University of Hong Kong, Shatin, Hong Kong
Clin Gastroenterol Hepatol 5:690-5. 2007..The aim of this study was to compare the clinical characteristics between patients with NERD and those with ERD...
- Cost-effectiveness of photodynamic therapy for treatment of Barrett's esophagus with high grade dysplasiaChin Hur
Gastrointestinal Unit and Institute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Dig Dis Sci 48:1273-83. 2003..In conclusion, PDT increases life expectancy and is cost-effective when compared to endoscopic surveillance and surgical esophagectomy...
- The expression of 8-hydroxydeoxyguanosine in oesophageal tissues and tumoursJ V Räsänen
Division of General Thoracic and Oesophageal Surgery, Department of Cardiothoracic Surgery, Helsinki University Central Hospital, Haartmaninkatu 4, PO Box 340, FIN 00029 HUS, Helsinki, Finland
Eur J Surg Oncol 33:1164-8. 2007..In the present study we investigated whether DNA damage linked to oxidative stress (as 8-OHdG) is present in Barrett's mucosa with or without associated adenocarcinoma or high-grade dysplasia and in normal controls' squamous mucosa...
- Circumferential endoscopic resection of Barrett's esophagus with high-grade dysplasia or early adenocarcinomaC V Lopes
Endoscopy Unit, Paoli Calmettes Institute, 232 Bd St Marguerite, 13273, Marseille, Cedex 9, France
Surg Endosc 21:820-4. 2007..Our objective was to evaluate the results of the circumferential EMR in removing not only the neoplastic lesion but also the remaining Barrett's epithelium...
- NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinomaPatricia C Galipeau
Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
PLoS Med 4:e67. 2007..We aimed to evaluate somatic genetic abnormalities with NSAIDs as predictors of EA in a prospective cohort study of patients with BE...
- Barrett's esophagus-emerging concepts and controversiesMatthew J Schuchert
J Surg Oncol 95:185-9. 2007
- [Barrett carcinoma--diagnosis, screening, surveillance, endoscopic treatment, prevention]U Peitz
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Medizinische Fakultät der Otto von Guericke Universität Magdeburg
Z Gastroenterol 45:1264-72. 2007..The rapid increase of the incidence of Barrett's carcinoma in Western countries suggests that life style factors, in particular overweight, having a causal role. Data from interventional trials on prevention are, however, pending...
- Surgical strategies for early esophageal adenocarcinomaH J Stein
Department of Surgery, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaningerstr 22, Munich, Germany
Best Pract Res Clin Gastroenterol 19:927-40. 2005..g. sentinel node techniques and artificial neural networks-may allow a further reduction of the invasiveness of surgical resection without compromising cure rates...
- A surveillance programme for Barrett's oesophagus in a UK general hospitalArikichenin Olithselvan
Gastroenterology Department, Wycombe Hospital, High Wycombe, Bucks, UK
Eur J Gastroenterol Hepatol 19:305-9. 2007..Surveillance programmes for oesophageal cancer in patients with Barrett's columnar-lined oesophagus have reported varying efficacies...
- Use of proton pump inhibitors may cause squamous epithelial masking of intramucosal carcinoma in Barrett's esophagusK Tanaka
Department of Endoscopic Medicine, Mie University School of Medicine, Tsu, Japan
Endoscopy 39:E105-6. 2007
- Can clinical and endoscopic findings accurately predict early-stage adenocarcinoma?G Portale
Division of Thoracic and Foregut Surgery, University of Southern California, 1510 San Pablo Street, Los Angeles, CA 90033, USA
Surg Endosc 20:294-7. 2006..Therefore, we conducted a study to determine whether symptomatic and endoscopic findings can accurately identify node-negative early-stage adenocarcinoma...
- Multiband mucosectomy for endoscopic resection of Barrett's esophagus: feasibility study with matched historical controlsFemke P Peters
Department of Gastroenterology, Academic Medical Center, Amsterdam, Netherlands
Eur J Gastroenterol Hepatol 19:311-5. 2007....
- Barrett's oesophagus: an audit of surveillance over a 17-year periodLisa Gladman
Gastroenterology Unit, City Hospital, Birmingham, B18 7QH, UK
Eur J Gastroenterol Hepatol 18:271-6. 2006..The incidence of adenocarcinoma was low compared with many published series, and we speculate whether this is the result of maintenance PPI therapy...
- Clinical and endoscopic factors predict higher pathologic grades of Barrett dysplasiaSharmila Anandasabapathy
Department of Gastroenterology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 109:668-74. 2007..Identifying simple, reliable, clinical, and endoscopic predictors of high-grade dysplasia and adenocarcinoma would be helpful for risk stratification in screening and surveillance programs...
- Getting categorical on GERDEamonn M M Quigley
Am J Gastroenterol 102:1130; author reply 1131. 2007
- Muscularis mucosae duplication and the musculo-fibrous anomaly in endoscopic mucosal resections for barrett esophagus: implications for staging of adenocarcinomaJason T Lewis
Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
Am J Surg Pathol 32:566-71. 2008....
- Short segment columnar-lined oesophagus: an underestimated cancer risk? A large cohort study of the relationship between Barrett's columnar-lined oesophagus segment length and adenocarcinoma riskPiers A C Gatenby
Department of Surgery, UK National Barrett s Oesophagus Registry, Royal Free and University College Medical School London, UK
Eur J Gastroenterol Hepatol 19:969-75. 2007..This study establishes adenocarcinoma risk in CLO by segment length...
- Molecular genetic analysis of surveillance biopsy samples from Barrett's mucosa--significance of samplingMeike Werther
Pathologie Nordhessen, Wilhelmshöher Allee 287, 34131 Kassel, Germany
Pathol Res Pract 204:285-94. 2008..Our results raise important questions regarding the biological dynamics of mutations in Barrett's mucosa in addition to the influence of sampling, especially with regard to the number of biopsies taken from Barrett's mucosa...
- Esophagitis: incidence and risk of esophageal adenocarcinoma--a population-based cohort studyAnnmarie Lassen
Department of Medical Gastroenterology, Odense University Hospital, Odense C, Denmark
Am J Gastroenterol 101:1193-9. 2006..CONCLUSION: The risk of esophageal adenocarcinoma is increased fivefold in patients with previously diagnosed esophagitis, but most of the adenocarcinomas occurred among patients with Barrett's esophagus...
- Epithelial-Refluxate Interactions in Barrett's EsophagusGeorge Triadafilopoulos; Fiscal Year: 2002..Overall, our study seeks to define the molecular signals that play a role in developing metaplasia and that regulate the acid- and bile-mediated responses in the esophagus. ..
- Epidemiologic Case-control Study of Barrett's EsophagusNicholas Shaheen; Fiscal Year: 2005..Finally, by comparing subjects with Barrett's to controls with reflux, and controlling for severs of reflux, the impact of a Barrett's diagnosis on quality of life and psychological stress may be seen. ..
- The Perception of Cancer Risk in Patients with Barrett's EsophagusNicholas Shaheen; Fiscal Year: 2007..The resultant study application will assess health-related quality of life, health-related anxiety and healthcare utilization as outcomes. ..
- Gene Expression in Barrett's EsophagusHashem El Serag; Fiscal Year: 2006..We present preliminary data on microarray and RT-PCRanalyses on 5 patients with BE that suggest an overactive Wnt pathway: we have also assembled the essential components of a successful study using microarrays. ..
- Obesity, H pylori and Risk of Barrett's EsophagusHashem B El Serag; Fiscal Year: 2010..Subsequently, in a case-control study, all newly diagnosed BE and randomly selected controls will be examined for the volume and activity of visceral obesity (CT scan and serum adipocytokines). ..
- Obesity, H pylori and Risk of Barrett's EsophagusHashem El Serag; Fiscal Year: 2009..Subsequently, in a case-control study, all newly diagnosed BE and randomly selected controls will be examined for the volume and activity of visceral obesity (CT scan and serum adipocytokines). ..
- Obesity, H pylori and Risk of Barrett's EsophagusHashem El Serag; Fiscal Year: 2007..Subsequently, in a case-control study, all newly diagnosed BE and randomly selected controls will be examined for the volume and activity of visceral obesity (CT scan and serum adipocytokines). ..
- Surveillance for Hepatocellular Carcinoma among HCV-infected VeteransHashem El Serag; Fiscal Year: 2007..Evaluating the extent and patterns of HCC surveillance is crucial in understanding diffusion (and obstacles) of this practice and in designing interventions to improve the implementation of HCC surveillance. ..
- Epidemiology and Outcomes of Digestive and Liver Diseases: A Mentoring ProgramHashem El Serag; Fiscal Year: 2007..pylori infection on BE tissue COX-2 expression. ..
- Surveillance for Hepatocellular Carcinoma among HCV-infected VeteransHashem El Serag; Fiscal Year: 2009..Evaluating the extent and patterns of HCC surveillance is crucial in understanding diffusion (and obstacles) of this practice and in designing interventions to improve the implementation of HCC surveillance. ..
- Biomarkers in Phototherapy of Barrett's EsophagusKenneth Wang; Fiscal Year: 2006..These observations can be extended to other forms of ablative therapy in future studies. ..
- Novel Method of Surveillance in Barrett's EsophagusKenneth Wang; Fiscal Year: 2007..This is an innovative method by which a physician can diagnose hidden areas of cancer within patients who are at a high risk of developing esophageal cancer. ..
- Anatomic and Mechanical Variables of the EGJ in GERDJohn Pandolfino; Fiscal Year: 2006..These changes will improve diagnostic accuracy of pH monitoring and also help determine the relationship between anatomical and mechanical variants and acid reflux. ..
- Endoscopic Therapy of Early Cancer in Barretts EsophagusKenneth Wang; Fiscal Year: 2007..Diagnostic and therapeutic techniques developed in this study can be applied to other gastrointestinal tumors. ..
- A NOVEL TECHNIQUE FOR SCREENING BARRETT'S ESOSPHAGUSKenneth Wang; Fiscal Year: 2003..The development of a screening device for Barrett's esophagus that could be operated by paramedical personnel would enable large-scale low cost screening to identify patients at risk for esophageal cancer. ..
- Biomarkers in Phototherapy of Barrett's EsophagusKenneth K Wang; Fiscal Year: 2010..These studies will provide an improved understanding regarding the response of Barrett's esophagus to ablation therapy. ..
- The mechanics of symptom generation in dysphagiaJohn Pandolfino; Fiscal Year: 2009..This proposal will utilize new analysis techniques to understand the cause of symptoms and determine what can be done to improve esophageal function so that symptoms can be reduced. ..
- Endoscopic Therapy of Early Cancer in Barretts EsophagusKenneth Wang; Fiscal Year: 2009..Diagnostic and therapeutic techniques developed in this study can be applied to other gastrointestinal tumors. ..
- The mechanics of symptom generation in dysphagiaJohn E Pandolfino; Fiscal Year: 2010..This proposal will utilize new analysis techniques to understand the cause of symptoms and determine what can be done to improve esophageal function so that symptoms can be reduced. ..
- THE ESOPHAGOGASTRIC JUNCTION IN HEALTH AND DISEASEPeter Kahrilas; Fiscal Year: 2009..A future direction for this research group will be to devise and test a "corrective intervention" based on those physiological objectives. ..
- THE ESOPHAGOGASTRIC JUNCTION IN HEALTH AND DISEASEPeter James Kahrilas; Fiscal Year: 2010..A future direction for this research group will be to devise and test a "corrective intervention" based on those physiological objectives. ..
- Risk Factors for Barrett's EsophagusBrian C Jacobson; Fiscal Year: 2010..These questions are especially relevant given our nation's current obesity epidemic. ..
- Epidemiology and Incidence of Barrett's EsophagusDOUGLAS ALLEN CORLEY; Fiscal Year: 2010..The proposed study explores how hormones associated with body fat may change the way the body heals after an injury, and increase the risk of cells developing precancerous changes. ..
- ETIOLOGIES/SURVEILLANCE OF BARRETT'S ESOPHAGUSDouglas Corley; Fiscal Year: 2003..abstract_text> ..
- THE ESOPHAGOGASTRIC JUNCTION IN HEALTH AND DISEASEPeter Kahrilas; Fiscal Year: 2005..abstract_text> ..
- Epidemiology and Incidence of Barrett's EsophagusDouglas Corley; Fiscal Year: 2006....
- Risk Factors for Barrett's EsophagusBrian Jacobson; Fiscal Year: 2007..M. Michael Wolfe, well-established investigators in health-services research. At the completion on the project, the candidate will have gained the experience to become an independent researcher in clinical epidemiology. ..
- GASTROENTEROLOGYDennis Jensen; Fiscal Year: 2007..Continued support is needed to maintain the quality and productivity of this program which is training future academicians in digestive diseases. ..
- UGI Hemorrhage and Barrett's EpitheliumDennis Jensen; Fiscal Year: 2007..This award will continue to enhance the applicant's research productivity and provide skilled mentoring for young investigators, so they can become independent patient-oriented investigators in digestive diseases. ..
- The Epidemiology of Adipokines in Barrett's EsophagusJoel Rubenstein; Fiscal Year: 2007..If so, measurement of these substances may be useful in a screening program. ..
- Role of eosinophils in intestinal epithelial dysfunctionGlenn Furuta; Fiscal Year: 2009..Long-term goals of these studies are the identification of specific diagnostic tests for EOGs and the development of novel eosinophil specific treatments. ..
- THE ESOPHAGOGASTRIC JUNCTION IN HEALTH AND DISEASEPeter Kahrilas; Fiscal Year: 2007..A future direction for this research group will be to devise and test a "corrective intervention" based on those physiological objectives. ..
- EOSINOPHIL PROTEINS AND GASTROINTESTINAL DISEASEGlenn Furuta; Fiscal Year: 2003..EDGP stimulated epithelial cell chloride ion secretion and 3. EDGP stimulated neutrophil infiltration, changes in vascular permeability and fluid secretion in vivo. ..
- Epidemiology and Incidence of Barrett's EsophagusDouglas Corley; Fiscal Year: 2009..The proposed study explores how hormones associated with body fat may change the way the body heals after an injury, and increase the risk of cells developing precancerous changes. ..
- Gastrointestinal Eosinophil Research SymposiumGlenn Furuta; Fiscal Year: 2006....