materials testing

Summary

Summary: The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.

Top Publications

  1. ncbi Size-dependent cytotoxicity of gold nanoparticles
    Yu Pan
    Biomedical Engineering, Biointerface Laboratory, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
    Small 3:1941-9. 2007
  2. ncbi How useful is SBF in predicting in vivo bone bioactivity?
    Tadashi Kokubo
    Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, 1200 Matsumoto, Kasugai, Aichi 487 8501, Japan
    Biomaterials 27:2907-15. 2006
  3. ncbi In vitro toxicity evaluation of graphene oxide on A549 cells
    Yanli Chang
    Institute of Nanochemistry and Nanobiology, Shanghai University, Shanghai 200444, China
    Toxicol Lett 200:201-10. 2011
  4. ncbi Nanostructured artificial nacre
    Zhiyong Tang
    Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    Nat Mater 2:413-8. 2003
  5. ncbi Antibacterial activity of two MTA-based root canal sealers
    R D Morgental
    Department of Endodontics, School of Dentistry, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil
    Int Endod J 44:1128-33. 2011
  6. ncbi Graphene thickness determination using reflection and contrast spectroscopy
    Z H Ni
    Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542
    Nano Lett 7:2758-63. 2007
  7. ncbi Hydration mechanisms of mineral trioxide aggregate
    J Camilleri
    Department of Building and Civil Engineering, Faculty of Architecture and Civil Engineering, University of Malta, Msida, Malta
    Int Endod J 40:462-70. 2007
  8. ncbi Resistance to fracture of endodontically treated teeth restored with different post systems
    Begum Akkayan
    Departmentof Prosthtic Dentistry, Faculty of Dentistry, University of Istanbul, Turkey
    J Prosthet Dent 87:431-7. 2002
  9. ncbi Improved bone-forming functionality on diameter-controlled TiO(2) nanotube surface
    Karla S Brammer
    Materials Science and Engineering, University of California, San Diego, La Jolla, CA 92093 0411, USA
    Acta Biomater 5:3215-23. 2009
  10. ncbi Cytotoxicity and immunological response of gold and silver nanoparticles of different sizes
    Hung Jen Yen
    Department of Chemical Engineering, National Chung Hsing University, 250 Kuo Kuang Road, Taichung 402, Taiwan, R O C
    Small 5:1553-61. 2009

Detail Information

Publications362 found, 100 shown here

  1. ncbi Size-dependent cytotoxicity of gold nanoparticles
    Yu Pan
    Biomedical Engineering, Biointerface Laboratory, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
    Small 3:1941-9. 2007
    ..The cellular response is size dependent, in that 1.4-nm particles cause predominantly rapid cell death by necrosis within 12 h while closely related particles 1.2 nm in diameter effect predominantly programmed cell death by apoptosis...
  2. ncbi How useful is SBF in predicting in vivo bone bioactivity?
    Tadashi Kokubo
    Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, 1200 Matsumoto, Kasugai, Aichi 487 8501, Japan
    Biomaterials 27:2907-15. 2006
    ....
  3. ncbi In vitro toxicity evaluation of graphene oxide on A549 cells
    Yanli Chang
    Institute of Nanochemistry and Nanobiology, Shanghai University, Shanghai 200444, China
    Toxicol Lett 200:201-10. 2011
    ..These effects are dose and size related, and should be considered in the development of bio-applications of GO. Overall, GO is a pretty safe material at cellular level, which is confirmed by the favorable cell growth on GO film...
  4. ncbi Nanostructured artificial nacre
    Zhiyong Tang
    Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    Nat Mater 2:413-8. 2003
    ..Structural and functional resemblance makes clay- polyelectrolyte multilayers a close replica of natural biocomposites. Their nanoscale nature enables elucidation of molecular processes occurring under stress...
  5. ncbi Antibacterial activity of two MTA-based root canal sealers
    R D Morgental
    Department of Endodontics, School of Dentistry, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil
    Int Endod J 44:1128-33. 2011
    ..To evaluate the pH and antibacterial activity of Endo CPM Sealer and MTA Fillapex by two different methods, using white MTA and Endofill as references for comparison...
  6. ncbi Graphene thickness determination using reflection and contrast spectroscopy
    Z H Ni
    Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542
    Nano Lett 7:2758-63. 2007
    ..We also show that the refractive index of graphene is different from that of graphite. The results are compared with those obtained using Raman spectroscopy...
  7. ncbi Hydration mechanisms of mineral trioxide aggregate
    J Camilleri
    Department of Building and Civil Engineering, Faculty of Architecture and Civil Engineering, University of Malta, Msida, Malta
    Int Endod J 40:462-70. 2007
    ..To report the hydration mechanism of white mineral trioxide aggregate (White MTA, Dentsply, Tulsa Dental Products, Tulsa, OK, USA)...
  8. ncbi Resistance to fracture of endodontically treated teeth restored with different post systems
    Begum Akkayan
    Departmentof Prosthtic Dentistry, Faculty of Dentistry, University of Istanbul, Turkey
    J Prosthet Dent 87:431-7. 2002
    ..Purpose. This in vitro study compared the effect of 1 titanium and 3 esthetic post systems on the fracture resistance and fracture patterns of crowned, endodontically treated teeth...
  9. ncbi Improved bone-forming functionality on diameter-controlled TiO(2) nanotube surface
    Karla S Brammer
    Materials Science and Engineering, University of California, San Diego, La Jolla, CA 92093 0411, USA
    Acta Biomater 5:3215-23. 2009
    ....
  10. ncbi Cytotoxicity and immunological response of gold and silver nanoparticles of different sizes
    Hung Jen Yen
    Department of Chemical Engineering, National Chung Hsing University, 250 Kuo Kuang Road, Taichung 402, Taiwan, R O C
    Small 5:1553-61. 2009
    ....
  11. ncbi Mineral trioxide aggregate: a comprehensive literature review--Part I: chemical, physical, and antibacterial properties
    Masoud Parirokh
    Department of Endodontics, School of Dentistry, Oral and Dental Diseases Research Center, Neuroscience Research Center, Iranian Center for Endodontic Research, Kerman University of Medical Sciences, Kerman, Iran
    J Endod 36:16-27. 2010
    ..The aim of Part I of this literature review is to present investigations regarding the chemical, physical, and antibacterial properties of MTA...
  12. ncbi Effect of pH on sealing ability of white mineral trioxide aggregate as a root-end filling material
    Mohammad Ali Saghiri
    Department of Biomedical Engineering, Islamic Azad University, Tehran, Iran
    J Endod 34:1226-9. 2008
    ..4 followed by pH values of 5.4, 6.4, and 7.4, respectively. There was a significantly longer time necessary for leakage to occur in samples stored in higher pH values (P < .000)...
  13. ncbi Tough, bio-inspired hybrid materials
    E Munch
    Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Science 322:1516-20. 2008
    ..These model materials can be used to identify the key microstructural features that should guide the synthesis of bio-inspired ceramic-based composites with unique strength and toughness...
  14. ncbi Animal models for implant biomaterial research in bone: a review
    A I Pearce
    AO Research Institute, AO Foundation, Clavadelerstrasse 8, Davos, Switzerland
    Eur Cell Mater 13:1-10. 2007
    ....
  15. ncbi Titania nanotubes: a novel platform for drug-eluting coatings for medical implants?
    Ketul C Popat
    Department of Physiology Division of Bioengineering, University of California, San Francisco, CA 94143, USA
    Small 3:1878-81. 2007
  16. ncbi Comparison of the physical and mechanical properties of MTA and portland cement
    Intekhab Islam
    Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore
    J Endod 32:193-7. 2006
    ..Further in vitro and in vivo tests, especially with regards its biocompatibility, should be conducted to ascertain if it meets the FDA requirements for use as a medical device...
  17. ncbi Increased osteoblast adhesion on nanophase metals: Ti, Ti6Al4V, and CoCrMo
    Thomas J Webster
    Department of Biomedical Engineering, Purdue University, 1296Patter Building, West Lafayette, IN 47905, USA
    Biomaterials 25:4731-9. 2004
    ....
  18. ncbi Rat tissue reaction to MTA FILLAPEX®
    João Eduardo Gomes-Filho
    Department of Endodontics, Araçatuba School of Dentistry, University of Estadual Paulista, R Jose Bonifacio 1193, Aracatuba, Sao Paulo, Brazil
    Dent Traumatol 28:452-6. 2012
    ..Mineralization and granulation birefringent to polarized light were observed with all materials. It was concluded that MTA FILLAPEX® was biocompatible and stimulated mineralization...
  19. ncbi The influence of hierarchical hybrid micro/nano-textured titanium surface with titania nanotubes on osteoblast functions
    Lingzhou Zhao
    School of Stomatology, The Fourth Military Medical University, No 145 West ChangLe Road, Xi an 710032, China
    Biomaterials 31:5072-82. 2010
    ..Our study reveals a synergistic role played by the micro and nanotopographies in osteoblast functions and provides insight to the design of better biomedical implant surfaces...
  20. ncbi The significance of infection related to orthopedic devices and issues of antibiotic resistance
    Davide Campoccia
    Research Unit on Implant Infections, Rizzoli Orthopedic Institute, Via di Barbiano, 1 10, 40136 Bologna, Italy
    Biomaterials 27:2331-9. 2006
    ....
  21. ncbi Magnesium hydroxide temporarily enhancing osteoblast activity and decreasing the osteoclast number in peri-implant bone remodelling
    C Janning
    Laboratory for Biomechanics and Biomaterials, Department of Orthopaedic Surgery, Hannover Medical School, Anna von Borries Strasse 1 7, 30625 Hannover, Germany
    Acta Biomater 6:1861-8. 2010
    ..Further studies have to evaluate if the enhanced bone growth is mainly due to the local magnesium ion concentration or the local alkalosis accompanying the Mg(OH)(2) dissolution...
  22. ncbi Does a low-shrinking composite induce less stress at the adhesive interface?
    Annelies Van Ende
    Leuven BIOMAT Research Cluster, Department of Conservative Dentistry, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Catholic University of Leuven, Kapucijnenvoer 7, 3000 Leuven, Belgium
    Dent Mater 26:215-22. 2010
    ..Therefore, we investigated the effect of C-factor (flat surface vs. class-I cavity) and different composite application protocols on the bonding effectiveness of a low-shrinking composite to human dentin...
  23. ncbi A multiparametric assay to compare the cytotoxicity of endodontic sealers with primary human osteoblasts
    M Z Scelza
    Laboratory of Experimental Cell Culture, Department of Endodontics, Fluminense Federal University UFF, Niteroi, RJ Brazil
    Int Endod J 45:12-8. 2012
    ....
  24. ncbi Optimal cytocompatibility of a bioceramic nanoparticulate cement in primary human mesenchymal cells
    Gustavo De-Deus
    Department of Endodontics, Veiga de Almeida University, Rio de Janeiro, Brazil
    J Endod 35:1387-90. 2009
    ..White Pro-Root MTA (Dentsply, Tulsa Dental, Tulsa, OK) was used as a reference for comparison...
  25. ncbi Influence of surface treatments and resin cement selection on bonding to densely-sintered zirconium-oxide ceramic
    Raquel Castillo de Oyagüe
    Department of Prosthodontics, Faculty of Dentistry, University Complutense of Madrid, Madrid, Spain
    Dent Mater 25:172-9. 2009
    ..To evaluate the effect of surface conditioning on the microtensile bond strength of zirconium-oxide ceramic to dual-cured resin cements...
  26. pmc Nanopattern-induced changes in morphology and motility of smooth muscle cells
    Evelyn K F Yim
    Department of Biomedical Engineering, The Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    Biomaterials 26:5405-13. 2005
    ..It is proposed that this nanoimprinting technology will provide a valuable platform for studies in cell-substrate interactions and for development of medical devices with nanoscale features...
  27. ncbi Carbon nanotubes with high bone-tissue compatibility and bone-formation acceleration effects
    Yuki Usui
    Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto Nagano 390 8621, Japan
    Small 4:240-6. 2008
    ..These findings should encourage development of clinical treatment modalities involving CNTs...
  28. ncbi Advancing dental implant surface technology--from micron- to nanotopography
    Gustavo Mendonça
    Universidade Catolica de Brasilia, Pos Graduacao em Ciencias Genomicas e Biotecnologia, SGAN Quadra 916, Av W5 Norte 70 790 160 Brasília, DF, Brazil
    Biomaterials 29:3822-35. 2008
    ..Nanoscale modification of titanium endosseous implant surfaces can alter cellular and tissue responses that may benefit osseointegration and dental implant therapy...
  29. pmc Nano rough micron patterned titanium for directing osteoblast morphology and adhesion
    Sabrina Puckett
    Division of Engineering, Brown University, Providence, RI 02917, USA
    Int J Nanomedicine 3:229-41. 2008
    ....
  30. ncbi Antibacterial coatings on titanium implants
    Lingzhou Zhao
    School of Stomatology, The Fourth Military Medical University, Xi an 710072, People s Republic of China
    J Biomed Mater Res B Appl Biomater 91:470-80. 2009
    ..One important strategy is to render the implant surface antibacterial by impeding the formation of a biofilm. A number of approaches have been proposed for this purpose and they are reviewed in this article...
  31. ncbi Evaluation of electrospun PCL/gelatin nanofibrous scaffold for wound healing and layered dermal reconstitution
    E J Chong
    Nanoscience and Nanotechnology Initiative, National University of Singapore, 9 Engineering Drive 1, Singapore 117576, Singapore
    Acta Biomater 3:321-30. 2007
    ....
  32. ncbi In vivo corrosion of four magnesium alloys and the associated bone response
    F Witte
    Department of Orthopaedic Surgery, Hannover Medical School, Anna von Borries Str 1 7, 30625 Hannover, Germany
    Biomaterials 26:3557-63. 2005
    ..From the results of this study, there is a strong rationale that in this research model, high magnesium ion concentration could lead to bone cell activation...
  33. ncbi In vitro corrosion and biocompatibility of binary magnesium alloys
    Xuenan Gu
    State Key Laboratory for Turbulence and Complex System and Department of Advanced Materials and Nanotechnology, College of Engineering, Peking University, Beijing 100871, China
    Biomaterials 30:484-98. 2009
    ..The relationship between the corrosion products and the in vitro biocompatibility had been discussed and the suitable alloying elements for the biomedical applications associated with bone and blood vessel had been proposed...
  34. pmc Magnetic poly(ε-caprolactone)/iron-doped hydroxyapatite nanocomposite substrates for advanced bone tissue engineering
    A Gloria
    Institute of Composite and Biomedical Materials, National Research Council, Naples 80125, Italy
    J R Soc Interface 10:20120833. 2013
    ....
  35. ncbi Interfacing live cells with nanocarbon substrates
    Shuchi Agarwal
    School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, Singapore 637457
    Langmuir 26:2244-7. 2010
    ..These observations could be attributed to the distinct nanotopographic features of these two kinds of nanocarbon substrates...
  36. ncbi In vivo evaluation of anodic TiO2 nanotubes: an experimental study in the pig
    Cornelius von Wilmowsky
    Department of Oral and Maxillofacial Surgery, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    J Biomed Mater Res B Appl Biomater 89:165-71. 2009
    ..Because of their simple, low cost, flexible manufacturing and the possibility for the usage as drug or growth factor delivery system, nanotubes seem to be a promising method for future medical implant coatings...
  37. ncbi Mineral trioxide aggregate: a review of the constituents and biological properties of the material
    J Camilleri
    Department of Conservative Dentistry, Dental Institute, King s College London, London, UK
    Int Endod J 39:747-54. 2006
    ..Relatively few articles addressed the constituents of MTA, whilst cytological evaluation was the most widely used biocompatibility test...
  38. ncbi Effect of zirconium-oxide ceramic surface treatments on the bond strength to adhesive resin
    Saadet Saglam Atsu
    Department of Prosthodontics, Kirikkale University, Faculty of Dental Medicine, Turkey
    J Prosthet Dent 95:430-6. 2006
    ..Surface treatment methods used for resin bonding to conventional silica-based dental ceramics are not reliable for zirconium-oxide ceramics...
  39. ncbi Oxygen switching of the epitaxial graphene-metal interaction
    Rosanna Larciprete
    CNR Institute for Complex Systems, Via Fosso del Cavaliere 100, 00133 Roma, Italy
    ACS Nano 6:9551-8. 2012
    ....
  40. pmc Polyacrylonitrile nanofibers coated with silver nanoparticles using a modified coaxial electrospinning process
    Deng Guang Yu
    School of Materials Science and Engineering, University of Shanghai for Science and Technology, Shanghai, People s Republic of China
    Int J Nanomedicine 7:5725-32. 2012
    ..Through manipulation of the distribution on the surface of nanofibers, the antibacterial effect of Ag can be improved substantially...
  41. ncbi Preparation of hydroxyapatite-gelatin nanocomposite
    Myung Chul Chang
    MDRCBB, School of Dentistry, University of Minnesota, 16 280 Moos Tower, 515 Delaware S E Minneapolis, MN 55455 0329, USA
    Biomaterials 24:2853-62. 2003
    ..This in turn will lead to the creation of a large number of tiny nanocrystals at this higher GEL concentration...
  42. ncbi The effectiveness of different acid irrigating solutions in root canal cleaning after hand and rotary instrumentation
    Mercedes Pérez-Heredia
    Department of Dental Pathology and Therapeutics, School of Dentistry, University of Granada Spain, Campus de Cartuja, Granada, Spain
    J Endod 32:993-7. 2006
    ..However, 2.5% NaOCl did not remove smear layer or debris, and no significant differences in debris were observed between manual and rotary techniques...
  43. ncbi Volume contraction in photocured dental resins: the shrinkage-conversion relationship revisited
    Magali Dewaele
    Ecole de Médecine Dentaire et de Stomatologie, Universite Catholique de Louvain, Bruxelles, Belgium
    Dent Mater 22:359-65. 2006
    ..Ideal dental composite would show an optimal degree of conversion and minimal polymerization shrinkage. These seem to be antagonistic goals, as increased monomer conversion invariably leads to high polymerization shrinkage values...
  44. ncbi Cell selective response to gold nanoparticles
    Hirak K Patra
    Department of Biochemistry, Calcutta University, Kolkata, India
    Nanomedicine 3:111-9. 2007
    ..This was confirmed by confocal microscopy, a green scattering (possibly, surface-enhanced Raman effect) appearing on selective z-slices of the image...
  45. ncbi Antibiotic resistance in exopolysaccharide-forming Staphylococcus epidermidis clinical isolates from orthopaedic implant infections
    Carla Renata Arciola
    Research Unit on Implant Infections, Rizzoli Orthopaedic Institute, Via Di Barbiano 1 10, 40136 Bologna, Italy
    Biomaterials 26:6530-5. 2005
    ..Moreover, multiple resistance to antibiotics was more frequent among exopolysaccharide-forming strains...
  46. ncbi Silver ion release from antimicrobial polyamide/silver composites
    Radhesh Kumar
    Institute of Polymer Materials, Friedrich Alexander University, Erlangen Nurnberg, Martensstr 7, 91058 Erlangen, Germany
    Biomaterials 26:2081-8. 2005
    ..However particles with higher (1.16 and 2.5 m(2)/g) SSA possess an agglomerated morphology leading to lower Ag(+) release. The composites are found to release Ag(+) at a concentration level capable of rendering an antimicrobial efficacy...
  47. ncbi Surface-mediated gene transfer from nanocomposites of controlled texture
    Hong Shen
    School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, New York 14853, USA
    Nat Mater 3:569-74. 2004
    ..DNA/mineral nanocomposite surfaces represent a promising system for enhancing gene transfer and controlling the extent of gene transfer for various biomedical applications, including tissue engineering or gene therapy of bone...
  48. ncbi Enhanced osteocalcin expression by osteoblast-like cells (MC3T3-E1) exposed to bioactive coating glass (SiO2-CaO-P2O5-MgO-K2O-Na2O system) ions
    V G Varanasi
    Division of Biomaterials and Bioengineering, University of California, San Francisco, CA 94143 0758, USA
    Acta Biomater 5:3536-47. 2009
    ..These results indicated the enhanced effect of bioactive glass ions on key osteogenic markers important for the bone healing process...
  49. ncbi The influence of structural design of PLGA/collagen hybrid scaffolds in cartilage tissue engineering
    Wenda Dai
    Biomaterials Center, National Institute for Materials Science, 1 1 Namiki, Tsukuba, Ibaraki 305 0044, Japan
    Biomaterials 31:2141-52. 2010
    ..These scaffolds could be used for the tissue engineering of articular cartilage with adjustable thickness. The design of the hybrid structures provides a strategy for the preparation of 3D porous scaffolds...
  50. ncbi Fatigue and biocompatibility properties of a poly(methyl methacrylate) bone cement with multi-walled carbon nanotubes
    Ross Ormsby
    School of Mechanical and Aerospace Engineering, Queen s University of Belfast, Ashby Building, Stranmillis Road, Belfast BT9 5AH, UK
    Acta Biomater 8:1201-12. 2012
    ..Cell viability was determined over 7 days in vitro using the standard colorimetric MTT assay. Confocal scanning laser microscopy and SEM analysis was also used to assess cell morphology on the various substrates...
  51. ncbi Variables related to materials and preparing for bond strength testing irrespective of the test protocol
    Lawrence Mair
    University of Central Lancashire, School of Dentistry, University of Central Lancashire, Preston PR1 2HE, United Kingdom
    Dent Mater 26:e17-23. 2010
    ..The treatment of the surface prior to bonding can be physical (e.g. sandblasting) or chemical (e.g. metal primer); but is more likely to be a combination (e.g. silica deposition+silane)...
  52. ncbi Changes in the surface of four calcium silicate-containing endodontic materials and an epoxy resin-based sealer after a solubility test
    R P Borges
    Department of Endodontics, University of Ribeirao Preto, Ribeirao Preto, Sao Paulo, Brazil
    Int Endod J 45:419-28. 2012
    ....
  53. ncbi The effect of pH on surface hardness and microstructure of mineral trioxide aggregate
    M S Namazikhah
    Private Practice, Beverly Hills, CA, USA
    Int Endod J 41:108-16. 2008
    ..In addition, the morphological microstructure features of samples were studied by scanning electron microscopy (SEM)...
  54. ncbi Binary and ternary doping of nitrogen, boron, and phosphorus into carbon for enhancing electrochemical oxygen reduction activity
    Chang Hyuck Choi
    Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 305 701, Republic of Korea
    ACS Nano 6:7084-91. 2012
    ....
  55. ncbi Setting characteristics and cavity adaptation of low-shrinking resin composites
    Dimitris Papadogiannis
    Department of Biomaterials, School of Dentistry, University of Athens, Greece
    Dent Mater 25:1509-16. 2009
    ..The aim of this study was to evaluate the setting characteristics of low-shrinking resin composites and examine the possible interactions with curing efficiency and marginal adaptation in dentin cavities...
  56. ncbi Diffusion in musculoskeletal tissue engineering scaffolds: design issues related to porosity, permeability, architecture, and nutrient mixing
    Tejas S Karande
    Center for Clinical Bioengineering, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    Ann Biomed Eng 32:1728-43. 2004
    ..The different types of biomaterials used, scaffold fabrication techniques implemented and the pore sizes/porosities obtained over the past 5 years have also been addressed...
  57. ncbi The effect of different surface treatments on bond strength between leucite reinforced feldspathic ceramic and composite resin
    Andrea Fabianelli
    Department of Dental Materials, University of Siena, Italy
    J Dent 38:39-43. 2010
    ..The aim of this study was to evaluate the effect of different surface treatments on the microtensile bond strength between a leucite reinforced glass-ceramic and composite resin...
  58. pmc In vitro assessments of nanomaterial toxicity
    Clinton F Jones
    Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT 84112 5820, USA
    Adv Drug Deliv Rev 61:438-56. 2009
    ..A diverse portfolio of complementary material characterization tools and bioassays are required to validate nanomaterial properties in physiology...
  59. ncbi Mechanical properties of a novel PVA hydrogel in shear and unconfined compression
    J A Stammen
    Georgia Institute of Technology, Atlanta 30332, USA
    Biomaterials 22:799-806. 2001
    ..Compressive failure of the hydrogels was found to occur between 45 and 60% strain, depending on water content...
  60. ncbi Nanoleakage, ultramorphological characteristics, and microtensile bond strengths of a new low-shrinkage composite to dentin after artificial aging
    Sillas Duarte
    Department of Comprehensive Care, Case Western Reserve University, School of Dental Medicine, 10900 Euclid Avenue, Cleveland, OH 44106 4905, USA
    Dent Mater 25:589-600. 2009
    ..The null hypotheses tested were (1) aging does not affect the bonding of low-shrinkage composite; (2) there is no difference in microtensile bond strengths and nanoleakage using different bonding strategies...
  61. ncbi Static frictional force and surface roughness of various bracket and wire combinations
    Umal H Doshi
    Department of Orthodontics, Government Dental College and Hospital, Nagpur, Maharashtra, India
    Am J Orthod Dentofacial Orthop 139:74-9. 2011
    ..019 × 0.025-in)-stainless steel, nickel-titanium, titanium-molybdenum alloy (TMA), and low-friction colored TMA...
  62. ncbi In vitro study of frictional forces during sliding mechanics of "reduced-friction" brackets
    Meir Redlich
    Department of Orthodontics, Hebrew University Hadassah Faculty of Dental Medicine, Jerusalem, Israel
    Am J Orthod Dentofacial Orthop 124:69-73. 2003
    ..This study demonstrates that not all brackets provide "reduced friction," even though the manufacturers describe them as doing so...
  63. ncbi Folate-conjugated amphiphilic hyperbranched block copolymers based on Boltorn H40, poly(L-lactide) and poly(ethylene glycol) for tumor-targeted drug delivery
    Mani Prabaharan
    Department of Mechanical Engineering, University of Wisconsin Milwaukee, Milwaukee, WI 53211, USA
    Biomaterials 30:3009-19. 2009
    ..These results indicated that the micelles prepared from the H40-PLA-b-MPEG/PEG-FA block copolymer have great potential as tumor-targeted drug delivery nanocarriers...
  64. pmc Flow measurement by cardiovascular magnetic resonance: a multi-centre multi-vendor study of background phase offset errors that can compromise the accuracy of derived regurgitant or shunt flow measurements
    Peter D Gatehouse
    CMR Unit, Royal Brompton Hospital, London, UK
    J Cardiovasc Magn Reson 12:5. 2010
    ..We studied the severity of uncorrected velocity offset errors across sites and CMR systems...
  65. ncbi A mineral trioxide aggregate sealer stimulated mineralization
    João Eduardo Gomes-Filho
    Department of Endodontics, Araçatuba School of Dentistry, Sao Paulo State University, Sao Paulo, Brazil
    J Endod 35:256-60. 2009
    ..Mineralization and granulations birefringent to the polarized light were observed with all materials. It was possible to conclude that Endo-CPM-Sealer was biocompatible and stimulated mineralization...
  66. ncbi Adsorption/desorption phenomena on pure and Teflon AF-coated titania surfaces studied by dynamic contact angle analysis
    F Rupp
    Department of Prosthetic Dentistry, Medical Materials and Technology, University of Tuebingen, Osianderstrasse 2 8, D 72076 Tuebingen, Germany
    J Biomed Mater Res 62:567-78. 2002
    ....
  67. pmc Surface modification for enhanced silanation of zirconia ceramics
    J R Piascik
    RTI International, Center for Materials and Electronic Technologies, Research Triangle Park, NC 27709 2194, USA
    Dent Mater 25:1116-21. 2009
    ..e. zirconia) to facilitate viable, robust adhesive bonding using commercially available silanes and resin cements...
  68. ncbi Mixed-mode failure strength of implant-cement interface specimens with varying surface roughness
    J Zelle
    Orthopaedic Research Laboratory, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    J Biomech 44:780-3. 2011
    ..The findings presented in this paper can be used in numerical models to simulate loosening at the implant-cement interface...
  69. ncbi Exfoliation and characterization of bismuth telluride atomic quintuples and quasi-two-dimensional crystals
    Desalegne Teweldebrhan
    Department of Electrical Engineering and Materials Science, Bourns College of Engineering, University of California Riverside, Riverside, California 92521, USA
    Nano Lett 10:1209-18. 2010
    ..The developed technology for producing free-standing quasi-2D layers of Te((1))-Bi-Te((2))-Bi-Te((1)) creates an impetus for investigation of the topological insulators and their possible practical applications...
  70. ncbi Osseointegration of alumina with a bioactive coating under load-bearing and unloaded conditions
    Anita Ignatius
    Institute of Orthopaedic Research and Biomechanics, University of Ulm, Helmholtzstrasse 14, 89081 Ulm, Germany
    Biomaterials 26:2325-32. 2005
    ..It was suggested that the osseointegration of Al(2)O(3) could be improved by the coating under load-bearing conditions, under which uncoated Al(2)O(3) ceramics cannot directly bind to bone...
  71. ncbi Biomechanical comparison of different surface modifications for dental implants
    Stephen J Ferguson
    Institute for Surgical Technology and Biomechanics, University of Bern, Switzerland
    Int J Oral Maxillofac Implants 23:1037-46. 2008
    ....
  72. doi Tailoring the atomic structure of graphene nanoribbons by scanning tunnelling microscope lithography
    Levente Tapasztó
    Nat Nanotechnol 3:397-401. 2008
    ..This method avoids the difficulties of assembling nanoscale components and may prove useful in the realization of complete integrated circuits, operating as room-temperature ballistic electronic devices...
  73. ncbi Curing effectiveness of resin composites at different exposure times using LED and halogen units
    Laura Ceballos
    Conservative Dentistry, Department of Health Sciences III, Health Science Faculty, Rey Juan Carlos University, Madrid, Spain
    Med Oral Patol Oral Cir Bucal 14:E51-6. 2009
    ..To compare the polymerization effectiveness of two resin composites cured with a quartz tungsten halogen (QTH) lamp or a light emitting diodes (LED) unit...
  74. pmc Induction of osteoblast differentiation phenotype on poly(L-lactic acid) nanofibrous matrix
    Jiang Hu
    Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI 48109 1078, USA
    Biomaterials 29:3815-21. 2008
    ..Inhibition of RhoA effector ROCK induced BSP gene expression of cells in AA-free medium on flat PLLA films. These results suggest that the nanofibers promote the differentiation of osteoblasts likely through RhoA-Rock signaling pathway...
  75. ncbi Influence of NaOCl deproteinization on shear bond strength in function of dentin depth
    Manuel Toledano
    Department of Dental Materials, School of Dentistry, University of Granada, Spain
    Am J Dent 15:252-5. 2002
    ..To determine the influence of NaOCl application on shear bond strengths (SBS) to superficial and deep dentin, using Prime & Bond 2.1...
  76. ncbi The role of sterilization in the cytocompatibility of titania nanotubes
    Lingzhou Zhao
    School of Stomatology, The Fourth Military Medical University, 145 West Changle Road, Xi an 710032, China
    Biomaterials 31:2055-63. 2010
    ..UV sterilization is found to be the best method from the viewpoint of surface contamination elimination...
  77. ncbi Effects of irrigation solutions on dentin wettability and roughness
    Xiaoli Hu
    Department of Operative Dentistry and Endodontics, Guanghua College of Stomatology, Sun Yat Sen University, Guangzhou, China
    J Endod 36:1064-7. 2010
    ..It is hypothesized that irrigation solutions might influence the physicochemical properties of human root canal dentin including the wettability and roughness...
  78. ncbi Study of gelatin-containing artificial skin V: fabrication of gelatin scaffolds using a salt-leaching method
    Sang Bong Lee
    School of Chemical Engineering, College of Engineering, Hanyang University, Haengdang dong, Seungdong ku, Seoul 133 791, Republic of Korea
    Biomaterials 26:1961-8. 2005
    ..An in vivo study of cultured artificial dermal substitutes showed that an artificial dermis containing the fibroblasts enhanced the re-epithelialization of a full-thickness skin defect when compared to an acellular scaffold after 1 week...
  79. ncbi Preparation and characterization of bioactive mesoporous wollastonite - Polycaprolactone composite scaffold
    Jie Wei
    Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, PR China
    Biomaterials 30:1080-8. 2009
    ..Such improved properties of m-WPC should be helpful for developing new biomaterials and may have potential use in hard tissue repair...
  80. ncbi Role of halide ions and temperature on the morphology of biologically synthesized gold nanotriangles
    Akhilesh Rai
    Nanoscience Group, Materials Chemistry Division, National Chemical Laboratory, Pune 411 008, India
    Langmuir 22:736-41. 2006
    ..The results show that, by varying the temperature of reaction condition, the shape, size, and optical properties of anisotropic nanoparticles can be fine-tuned...
  81. ncbi Mechanical and histological evaluation of a PMMA-based bone cement modified with gamma-methacryloxypropyltrimethoxysilane and calcium acetate
    Tadashi Tsukeoka
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8677, Japan
    Biomaterials 27:3897-903. 2006
    ..The modification was found to be effective in enabling osteoconduction with PMMA bone cement, thus providing stable fixation for a long period after implantation...
  82. ncbi Surface characterizations and corrosion resistance of nickel-titanium orthodontic archwires in artificial saliva of various degrees of acidity
    Her Hsiung Huang
    Department of Chemical and Materials Engineering, National University of Kaohsiung, No 700, Kaohsiung University Road, Kaohsiung 811, Taiwan
    J Biomed Mater Res A 74:629-39. 2005
    ..The difference in the corrosion resistance among these NiTi dental orthodontic archwires did not correspond with the surface roughness and pre-existing defects...
  83. ncbi Grafting of gelatin on electrospun poly(caprolactone) nanofibers to improve endothelial cell spreading and proliferation and to control cell Orientation
    Zuwei Ma
    Nanoscience and Nanotechnology Initiative, National University of Singapore
    Tissue Eng 11:1149-58. 2005
    ..The surface-modified PCL nanofibrous material is a potential candidate material in blood vessel tissue engineering...
  84. ncbi In vitro/in vivo biocompatibility and mechanical properties of bioactive glass nanofiber and poly(epsilon-caprolactone) composite materials
    Ji Hoon Jo
    Department of Materials Science and Engineering, Seoul National University, Seoul, Korea
    J Biomed Mater Res B Appl Biomater 91:213-20. 2009
    ..These results indicate that the PCL/BGNF composite has greater bioactivity and mechanical stability when compared with the PCL/BG composite and great potential as a bone regenerative material...
  85. ncbi Influence of root embedment material and periodontal ligament simulation on fracture resistance tests
    Carlos Jose Soares
    Department of Operative Dentistry and Dental Materials, School of Dentistry, Federal University of Uberlandia
    Braz Oral Res 19:11-6. 2005
    ..05). The results showed that root embedment method and periodontal ligament simulation have a significant effect on fracture resistance. Artificial periodontal ligament modified the fracture modes...
  86. ncbi Bond strength of Epiphany sealer prepared with resinous solvent
    Fuad Jacob Abi Rached-Junior
    School of Dentistry, University of Ribeirao Preto, Sao Paulo, Brazil
    J Endod 35:251-5. 2009
    ..01). The resinous solvent of Epiphany system increased the bond strength of Epiphany sealer to dentin walls when followed by photoactivation...
  87. ncbi Staphylococcus aureus adhesion to different treated titanium surfaces
    L G Harris
    AO Research Institute, Clavadelerstrasse, CH7270 Davos Platz, Switzerland
    J Mater Sci Mater Med 15:311-4. 2004
    ..aureus was the titanium surface coated with sodium hyaluronate. Thus such a coating could have potential use as a coating for ostoesynthesis, orthopaedic or dental implants...
  88. ncbi Influence of filler on the difference between the transmitted and reflected colors of experimental resin composites
    Yong keun Lee
    Department of Dental Biomaterials Science and Dental Research Institute, School of Dentistry, Seoul National University, 28 Yeongeon dong, Jongro Gu, Seoul, Republic of Korea
    Dent Mater 24:1243-7. 2008
    ..This study sought to determine the influence of filler size and amount on the difference between the transmitted and reflected colors and the translucency of experimental resin composites...
  89. ncbi Translucency of zirconia copings made with different CAD/CAM systems
    Paolo Baldissara
    Alma Mater Studiorum University of Bologna, Department of Oral Sciences, Section of Prosthodontics, Via S Vitale 59, 40125 Bologna, Italy
    J Prosthet Dent 104:6-12. 2010
    ..Zirconia cores are reported to be less translucent than glass, lithium disilicate, or alumina cores. This could affect the esthetic appearance and the clinical choices made when using zirconia-based restorations...
  90. ncbi Chitosan/poly(epsilon-caprolactone) blend scaffolds for cartilage repair
    Sara C Neves
    3B s Research Group Biomaterials, Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Department of Polymer Engineering, University of Minho, Avepark, Zona Industrial da Gandra, S Cláudio do Barco 4806 909, Caldas das Taipas, Guimaraes, Portugal
    Biomaterials 32:1068-79. 2011
    ..In contrast to 100CHT scaffolds, ECM was homogenously deposited on the 75CHT and 50CHT scaffolds. Although mechanical properties of the 50CHT scaffold were better, the 75CHT scaffold facilitated better neo-cartilage formation...
  91. ncbi Physicomechanical evaluation of polypropylene, polyester, and polytetrafluoroethylene meshes for inguinal hernia repair
    Corey R Deeken
    Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Am Coll Surg 212:68-79. 2011
    ..The objectives of this study were to propose standard techniques, perform physicomechanical testing, and classify materials commonly used for inguinal hernia repair...
  92. ncbi Comparison of photo-activation versus chemical or dual-curing of resin-based luting cements regarding flexural strength, modulus and surface hardness
    N Hofmann
    Department of Operative Dentistry and Periodontology, Bavarian Julius Maximilians University of Würzburg, Germany
    J Oral Rehabil 28:1022-8. 2001
    ..In contrast, dual-curing maintained flexural strength for all, the modulus for three and the hardness for one of the materials. The mechanical properties of the self-curing resin cement ranged between those of the DC materials...
  93. ncbi The effect of surface treatment on the shear bond strength of luting cement to a glass-infiltrated alumina ceramic
    M Ozcan
    Department of Prosthodontics, Faculty of Dentistry, Marmara University, Istanbul, Turkey
    Int J Prosthodont 14:335-9. 2001
    ..The aim of this study was to evaluate the effect of three different surface treatments on the bond strength of four different luting cements--three bis-GMA-based resin cements and a compomer cement--to In-Ceram...
  94. ncbi Adhesion to tooth structure: a critical review of "macro" test methods
    Roberto R Braga
    University of Sao Paulo School of Dentistry, Dept of Dental Materials, Av Prof Lineu Prestes, 2227, Sao Paulo, SP 05508 000, Brazil
    Dent Mater 26:e38-49. 2010
    ..This review focuses on aspects related to specimen geometry and test mechanics of "macro" shear and tensile bond strength tests...
  95. pmc Reduced adhesion of macrophages on anodized titanium with select nanotube surface features
    Amancherla Rajyalakshmi
    Non Ferrous Materials Technology Development Centre, Hyderabad, India
    Int J Nanomedicine 6:1765-71. 2011
    ..This in vitro study thus demonstrated a reduced density of macrophages on anodized Ti, thereby providing further evidence of the greater efficacy of anodized Ti for orthopedic applications...
  96. ncbi Mechanical quality of tissue engineered cartilage: results after 6 and 12 weeks in vivo
    G N Duda
    Charite, Campus Virchow Klinikum, Humboldt University of Berlin, Augustenburger Platz 1, D 13353 Berlin, Germany
    J Biomed Mater Res 53:673-7. 2000
    ..As an adjunct to histological analysis, mechanical testing may be a valuable tool for judging the utility of engineered cartilage prior to a broad clinical usage...
  97. ncbi Cooperative modulation of neuritogenesis by PC12 cells by topography and nerve growth factor
    John D Foley
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, Wisconsin 53706, USA
    Biomaterials 26:3639-44. 2005
    ..These findings may have general relevance to differentiation processes in neurons as well as in other cell types...
  98. ncbi In vivo evaluation of plasma-sprayed wollastonite coating
    Weichang Xue
    Plasma Spray Laboratory, Shanghai Institute of Ceramics, Chinese Academy of Science, 1295 Dingxi Road, Shanghai 200050, People s Republic of China
    Biomaterials 26:3455-60. 2005
    ..The test in marrow indicated that wollastonite coatings could induce new bone formation on their surface showing good bone inductivity property...
  99. ncbi Electrospinning of nano/micro scale poly(L-lactic acid) aligned fibers and their potential in neural tissue engineering
    F Yang
    Department of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576
    Biomaterials 26:2603-10. 2005
    ..Based on the experimental results, the aligned nanofibrous PLLA scaffold could be used as a potential cell carrier in neural tissue engineering...
  100. ncbi Combined marrow stromal cell-sheet techniques and high-strength biodegradable composite scaffolds for engineered functional bone grafts
    Yefang Zhou
    Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore 119260, Singapore
    Biomaterials 28:814-24. 2007
    ....
  101. pmc Quantitative characterization of the influence of the nanoscale morphology of nanostructured surfaces on bacterial adhesion and biofilm formation
    Ajay Vikram Singh
    European School of Molecular Medicine, IFOM IEO, Milan, Italy
    PLoS ONE 6:e25029. 2011
    ....

Research Grants46

  1. Targeted siRNA nanotechnology for intravesical treatment of urologicaldiseases
    Robert M Weiss; Fiscal Year: 2010
    ..proteins that will stabilize and deliver siRNAs and drugs, to test their physicochemical properties (materials testing), and the capacity of the nanoparticles to release siRNA efficiently from the nanospheres to an ..
  2. Sex Hormones and Rat Anterior Cruciate Ligament Strength
    William A Romani; Fiscal Year: 2010
    ..To test this hypothesis the studies proposed in these specific aims will use a hydraulic materials testing device and Western blot analysis to measure ACL mechanical strength and collagen protein content in ..
  3. Testing to rank orthopaedic hip implant materials for their resistance to squeaki
    ANTHONY PAUL SANDERS; Fiscal Year: 2010
    ..This research project will analyze contact stresses in hip implants under worst case load conditions and will develop new wear test methods to improve the pre-clinical evaluation of next-generation implants and their materials. ..
  4. INTERLAKEN SERIES 3000 AXIAL-TORSIONAL MATERIALS TESTING
    Wilson Hayes; Fiscal Year: 1992
    ..These data will be applied toward evaluation of two different calcium-phosphate coatings and a surface treatment procedure. The goal of this project is to improve orthopaedic and dental implant fixation in bone...
  5. ICP-MS Instrument for Baylor College of Dentistry
    Kathy Svoboda; Fiscal Year: 2006
    ..The facility currently houses a range of materials testing machines for large and small specimens (Instron and Test Resources), machine tools for large and small ..
  6. MODULATION OF LOCAL BONE TISSUE MATERIAL PROPERTIES
    Clifford Les; Fiscal Year: 2004
    ..will be tested for structural damping, stiffness, and strength before sectioning into regions for materials testing and histology...
  7. MINIATURE IN-VIVO HYDROPHONES FOR LITHOTRIPTER USE
    MARK SCHAFER; Fiscal Year: 1990
    ..modeling to examine design trade-offs associated with material choice and sensor configuration; 2) materials testing to determine acoustical properties and durability; 3) prototype design and assembly; 4) acoustical ..
  8. Objective Assessment Instrumentation for Manual Therapy Techniques
    SUSAN DIEKRAGER; Fiscal Year: 2009
    ..The performance of the sensor will be tested by bench tests with known forces using a materials testing machine. Specific Aim 2: Develop and test a multi-cell 3D force sensor array...
  9. Application of alginate for endovascular embolization
    Timothy Becker; Fiscal Year: 2005
    ..The goal is to accomplish the next steps towards commercialization. Specific Aim 1 is to conduct materials testing of ALGEL-II to assess long-term stability and biocompatibility in small-neck aneurysms...
  10. INHALANT USE AMONG RURAL CHILDREN: A MULTICULTURAL STUDY
    Ruth Edwards; Fiscal Year: 2006
    ....
  11. A MECHANICAL SPECTROMETER FOR BIOLOGICAL MATERIALS
    GERARD D SOUZA; Fiscal Year: 1990
    ..In the proposed phase I work we will design a prototype materials testing machine to perform constant strain rate, creep (step change in load), stress relaxation (step change in ..
  12. Peptide Dimethacrylate Additives for Dental Composites
    KATHLEEN KILWAY; Fiscal Year: 2007
    ..G. Gutheil provides the capability to synthesize the peptides; and R.L. Sakaguchi contributes materials testing expertise and equipment as well as significant experience and knowledge of practical problems in dental ..
  13. Biomechanical and Molecular Mechanisms in Alveolar Bone Development
    TRACY POPOWICS; Fiscal Year: 2008
    ..these experimental conditions. Taken together, these studies will provide fundamental new information about how tooth loading modifies alveolar bone in newly erupted teeth and promotes adaptive tooth support. ..
  14. CERAMIC WHISKER REINFORCEMENT OF DENTAL COMPOSITE RESINS
    HUAKUN XU; Fiscal Year: 2002
    ....
  15. Effect of Femoral Stem Design om Cement Mantle Failure
    Amos Race; Fiscal Year: 2006
    ..Should these aims be met, the proposed model will be of great use in pre-clinical testing of novel cemented stem designs. ..
  16. Fatigue Crack Morphology in Cemented Hips
    Amos Race; Fiscal Year: 2002
    ....
  17. Proteomics of DEP-induced Oxidative Stress
    Andre Nel; Fiscal Year: 2006
    ..They will also use a display of protein carbonyls to identity oxidatively modified proteins in the BAL fluid. ..
  18. Osteoblast stimulation effects on osteoclast activity
    Marnie Saunders; Fiscal Year: 2006
    ..This work has several clinically relevant applications including implant- and metastatic-induced osteolysis, osteoporosis, osteopetrosis, fracture healing and functional tissue engineering. ..
  19. BION Treatment of Neuromuscular Dysfunction
    Gerald Loeb; Fiscal Year: 2006
    ..abstract_text> ..
  20. Capillary Electrophoresis Profiling of Tears in Dry Eye
    JEAN JACOB; Fiscal Year: 2006
    ....
  21. Annular and Sub-Valvular Repair Techniques for Ischemic Mitral Regurgitation: In-
    Ajit P Yoganathan; Fiscal Year: 2010
    ..abstract_text> ..
  22. Atherogenic Effects of Ambient PM In Susceptible Animals
    Andre Nel; Fiscal Year: 2007
    ..These mice will be exposed to CAPs as discussed in Aims 1 and 2, and select endpoints used to demonstrate the effect on atherosclerotic inflammation and apoptosis. ..
  23. FLEXOR TENDON HEALING
    Richard H Gelberman; Fiscal Year: 2010
    ..They will extend our understanding of the critical early stages of healing and will provide therapeutic solutions for the most prevalent clinical problems associated with tendon injury and repair. ..
  24. Development of methods and models for nanoparticle toxicity screening: Applicatio
    Andre Nel; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  25. Biosignatures Classifying Binge Alcohol-Induced Bone Damage and Drug Intervention
    John Callaci; Fiscal Year: 2009
    ....
  26. IN VIVO STUDIES OF SALIVA ANTIMICROBIAL PROTEINS
    JOEL RUDNEY; Fiscal Year: 2001
    ..By focusing on redundancy and complexing, this project also addresses the question of whether individual proteins exert unique and specific effects in the mouth. ..
  27. INTRACELLULAR TRAFFICKING OF TROPOELASTIN
    Frederick Grinnell; Fiscal Year: 2002
    ....
  28. FGF-Silyl-Heparin Cerebral Aneurysm Coils
    PAUL ZAMORA; Fiscal Year: 2002
    ..The Phase I studies will develop the coated coils and perform initial animal evaluations. ..
  29. BION Treatment of Neuromuscular Dysfunction
    Gerald Loeb; Fiscal Year: 2002
    ..abstract_text> ..
  30. VIRTUAL DENTAL PATIENT
    Ralph DeLong; Fiscal Year: 2001
    ..In light of these developments, an authenticated VDP seems not only possible and beneficial, but inevitable and of high program relevance. ..
  31. INTERFACIAL PROPERTIES OF HAVERSIAN BONE
    LANNY GRIFFIN; Fiscal Year: 2002
    ..Equine bone will be used to evaluate differences between primary and secondary osteons. Micromechanics and constitutive modeling will be performed. ..
  32. INJECTABLE SENSORS FOR CONTROL OF FES
    Gerald Loeb; Fiscal Year: 2002
    ....
  33. EPITHELIALIZATION OF TISSUE ENGINEERED CORNEAS
    JEAN JACOB; Fiscal Year: 2003
    ..The results of these studies will provide insight into the processes involved in the success or failure of corneal augmentation and replacement by artificial implants. ..
  34. Lipids rafts in JNK and Nk-kB activation by TCR/CD28
    Andre Nel; Fiscal Year: 2006
    ..We will compare T-cells from young and elderly human subjects to determine how altered cytoskeletal assembly contributes to signaling decline by the TCR. ..
  35. Fluid Mechanics of the Mitral Valve: In Vitro Studies
    Ajit Yoganathan; Fiscal Year: 2004
    ..The use of state of the art measurement systems unavailable for in vivo use will yield significant results. ..
  36. Biological Analysis of Toxic DEP Chemicals
    Andre Nel; Fiscal Year: 2006
    ..We will determine if inhaled ambient PM induce apoptosis in induced sputum samples in humans. ..
  37. Thromboresistant vascular grafts:heparin-peptidomimetics
    PAUL ZAMORA; Fiscal Year: 2004
    ..abstract_text> ..
  38. DEVELOPMENT OF AN IN VITRO WOUND HEALING MODEL
    Frederick Grinnell; Fiscal Year: 2008
    ..Specific Aim #3 focuses on the factors that contribute to apoptosis of cells undergoing stressed matrix contraction. ..
  39. Extracrevicular Invasion by Periodontal Pathogens
    JOEL RUDNEY; Fiscal Year: 2005
    ..abstract_text> ..
  40. Fluorescence Sensor Probe for Transcutaneous Glucose Sensing
    Ralph Ballerstadt; Fiscal Year: 2008
    ..The overall result will be a healthier life for people with diabetes and lower medical costs for diabetes care for the society. [unreadable] [unreadable] [unreadable]..
  41. Improving Flow Dynamics in Fontan Surgeries
    Ajit Yoganathan; Fiscal Year: 2006
    ....
  42. Thiol-Ene Polymers as Dental Restorative Materials
    NEIL CRAMER; Fiscal Year: 2006
    ..The compatibility of monomer formulations with filler particles and the properties of filled systems will be evaluated. Biocompatibility of the new dental restorative materials will also be assessed. ..
  43. Effectiveness of Intervention on Health
    Lisa Brosseau; Fiscal Year: 2003
    ..It is expected that the difference in mean pre- and post-study outcome beliefs (and perhaps intentions and attitudes) will be greater in the intervention than the control group. ..
  44. Biodurability of Dentin-Adhesive Resin Bond Joint
    Steven Armstrong; Fiscal Year: 2003
    ..abstract_text> ..
  45. Mesoporus Diamondlike Carbon Medical Device Membrane
    Roger Narayan; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..