intratracheal intubation

Summary

Top Publications

  1. ncbi [Anesthetic management of patients with tracheal bronchus]
    Mizuho Kawamoto
    Division of Anesthesia, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan
    Masui 57:152-7. 2008
  2. ncbi Endotracheal intubation in patients with cervical spine immobilization: a comparison of macintosh and airtraq laryngoscopes
    Chrisen H Maharaj
    Department of Anaesthesia, University College Hospital, Galway, Ireland
    Anesthesiology 107:53-9. 2007
  3. ncbi Patients' recollections of stressful experiences while receiving prolonged mechanical ventilation in an intensive care unit
    Armando J Rotondi
    University of Pittsburgh, Pittsburgh, PA
    Crit Care Med 30:746-52. 2002
  4. ncbi Prediction of difficult mask ventilation
    O Langeron
    Departement d Anesthesie Reanimation, Centre Hospitalo Universitaire Pitie Salpetriere, Universite Paris VI, Paris, France
    Anesthesiology 92:1229-36. 2000
  5. ncbi Noninvasive ventilation in immunosuppressed patients with pulmonary infiltrates, fever, and acute respiratory failure
    G Hilbert
    Division of Medical Intensive Care, University Hospital, Bordeaux, France
    N Engl J Med 344:481-7. 2001
  6. ncbi Tracheal intubation using the Bonfils intubation fibrescope after failed direct laryngoscopy
    B Bein
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig Holstein, Campus Kiel, Schwanenweg 21, D 24105 Kiel, Germany
    Anaesthesia 59:1207-9. 2004
  7. ncbi Incidence and predictors of difficult and impossible mask ventilation
    Sachin Kheterpal
    Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan 48103, USA
    Anesthesiology 105:885-91. 2006
  8. ncbi Difficult Airway Society guidelines for management of the unanticipated difficult intubation
    J J Henderson
    Anaesthetic Department, Gartnavel General Hospital, 1053 Great Western Road, Glasgow G12 0YN, UK
    Anaesthesia 59:675-94. 2004
  9. ncbi Endotracheal tube cuff pressure in intensive care unit: the need for pressure monitoring
    Samir Jaber
    Intensive Care Med 33:917-8. 2007
  10. ncbi Predicting difficult intubation in apparently normal patients: a meta-analysis of bedside screening test performance
    Toshiya Shiga
    Department of Anesthesia, Nippon Medical School Chiba Hokusoh Hospital, Kamagari, Chiba, Japan
    Anesthesiology 103:429-37. 2005

Detail Information

Publications245 found, 100 shown here

  1. ncbi [Anesthetic management of patients with tracheal bronchus]
    Mizuho Kawamoto
    Division of Anesthesia, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan
    Masui 57:152-7. 2008
    ..Therefore, the airway must be assessed carefully by fiberoptic bronchoscopy prior to unilateral lung surgery, keeping in mind the possibility of a tracheal bronchus, in order to design a safe way to secure it safely during the surgery...
  2. ncbi Endotracheal intubation in patients with cervical spine immobilization: a comparison of macintosh and airtraq laryngoscopes
    Chrisen H Maharaj
    Department of Anaesthesia, University College Hospital, Galway, Ireland
    Anesthesiology 107:53-9. 2007
    ..The authors compared ease of intubation with the Airtraq and Macintosh laryngoscopes in patients with cervical spine immobilization in a randomized, controlled clinical trial...
  3. ncbi Patients' recollections of stressful experiences while receiving prolonged mechanical ventilation in an intensive care unit
    Armando J Rotondi
    University of Pittsburgh, Pittsburgh, PA
    Crit Care Med 30:746-52. 2002
    ..To describe stressful experiences of adult patients who received mechanical ventilation for > or =48 hrs in an intensive care unit...
  4. ncbi Prediction of difficult mask ventilation
    O Langeron
    Departement d Anesthesie Reanimation, Centre Hospitalo Universitaire Pitie Salpetriere, Universite Paris VI, Paris, France
    Anesthesiology 92:1229-36. 2000
    ..Because the incidence of difficult mask ventilation (DMV) and the factors associated with it are not well known, we undertook this prospective study...
  5. ncbi Noninvasive ventilation in immunosuppressed patients with pulmonary infiltrates, fever, and acute respiratory failure
    G Hilbert
    Division of Medical Intensive Care, University Hospital, Bordeaux, France
    N Engl J Med 344:481-7. 2001
    ..Avoiding intubation is a major goal in the management of respiratory failure, particularly in immunosuppressed patients. Nevertheless, there are only limited data on the efficacy of noninvasive ventilation in these high-risk patients...
  6. ncbi Tracheal intubation using the Bonfils intubation fibrescope after failed direct laryngoscopy
    B Bein
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig Holstein, Campus Kiel, Schwanenweg 21, D 24105 Kiel, Germany
    Anaesthesia 59:1207-9. 2004
    ..5 (30-80 [20-200]) s. Tracheal intubation using the Bonfils intubation fibrescope appears to be a simple and effective technique for the management of a difficult intubation...
  7. ncbi Incidence and predictors of difficult and impossible mask ventilation
    Sachin Kheterpal
    Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan 48103, USA
    Anesthesiology 105:885-91. 2006
    ..Mask ventilation is an essential element of airway management that has rarely been studied as the primary outcome. The authors sought to determine the incidence and predictors of difficult and impossible mask ventilation...
  8. ncbi Difficult Airway Society guidelines for management of the unanticipated difficult intubation
    J J Henderson
    Anaesthetic Department, Gartnavel General Hospital, 1053 Great Western Road, Glasgow G12 0YN, UK
    Anaesthesia 59:675-94. 2004
    ..The flow-charts are simple, clear and definitive. They can be fully implemented only when the necessary equipment and training are available. The guidelines received overwhelming support from the membership of the DAS...
  9. ncbi Endotracheal tube cuff pressure in intensive care unit: the need for pressure monitoring
    Samir Jaber
    Intensive Care Med 33:917-8. 2007
  10. ncbi Predicting difficult intubation in apparently normal patients: a meta-analysis of bedside screening test performance
    Toshiya Shiga
    Department of Anesthesia, Nippon Medical School Chiba Hokusoh Hospital, Kamagari, Chiba, Japan
    Anesthesiology 103:429-37. 2005
    ..Combinations of tests add some incremental diagnostic value in comparison to the value of each test alone. The clinical value of bedside screening tests for predicting difficult intubation remains limited...
  11. ncbi Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation
    Chiu wing Lam
    Space and Life Sciences, NASA Johnson Space Center, Houston, Texas 77058, USA
    Toxicol Sci 77:126-34. 2004
    ....
  12. ncbi Difficult tracheal intubation is more common in obese than in lean patients
    Philippe Juvin
    Department of Anesthesia and Intensive Care, Bichat Claude Bernard Hospital, Paris, France
    Anesth Analg 97:595-600, table of contents. 2003
    ..None of the classic risk factors for difficult intubation was satisfactory in obese patients. The high risk of desaturation warrants studies to identify new predictors of difficult intubation in the obese...
  13. ncbi The Combitube as a salvage airway device for paramedic rapid sequence intubation
    Daniel P Davis
    Department of Emergency Medicine, University of California San Diego, San Diego, CA 92103 8676, USA
    Ann Emerg Med 42:697-704. 2003
    ..Here we describe our experience with the Combitube (esophageal-tracheal twin-lumen airway device) as a salvage airway device for paramedic rapid sequence intubation...
  14. ncbi A comparison of the GlideScope with the Macintosh laryngoscope for tracheal intubation in patients with simulated difficult airway
    Y Lim
    Department of Anaesthesia, KK Women s and Children s Hospital, Singapore
    Anaesth Intensive Care 33:243-7. 2005
    ..The GlideScope may be a good alternative for managing the difficult airway but clinical trials evaluating its use on patients with an actual difficult airway are needed...
  15. doi Pentax-AWS, a new videolaryngoscope, is more effective than the Macintosh laryngoscope for tracheal intubation in patients with restricted neck movements: a randomized comparative study
    Y Enomoto
    Department of Anaesthesiology, Koshigaya Hospital, Dokkyo Medical University, Koshigaya City, Saitama, Japan
    Br J Anaesth 100:544-8. 2008
    ..We studied whether laryngoscopy and tracheal intubation were easier when using the Pentax-AWS (Tokyo, Japan), a new videolaryngoscope, than when applying the Macintosh laryngoscope, during manual in-line neck stabilization...
  16. doi Tracheal intubation in patients with cervical spine immobilization: a comparison of the Airwayscope, LMA CTrach, and the Macintosh laryngoscopes
    M A Malik
    Department of Anaesthesia, Galway University Hospitals, Galway, Ireland
    Br J Anaesth 102:654-61. 2009
    ....
  17. ncbi The GlideScope Video Laryngoscope: randomized clinical trial in 200 patients
    D A Sun
    Department of Anesthesia, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    Br J Anaesth 94:381-4. 2005
    ..The aim of the study was to describe the use of the GlideScope in comparison with direct laryngoscopy for elective surgical patients requiring tracheal intubation...
  18. ncbi A prospective, randomized, study comparing early percutaneous dilational tracheotomy to prolonged translaryngeal intubation (delayed tracheotomy) in critically ill medical patients
    Mark J Rumbak
    Department of Medicine, Division of Pulmonary, Critical Care and Occupation Medicine, Tampa General Hospital University of South Florida Health Science Center, Tampa, FL 33612, USA
    Crit Care Med 32:1689-94. 2004
    ..The effects of early percutaneous dilational tracheotomy compared with delayed tracheotomy in critically ill medical patients needing prolonged mechanical ventilation were assessed...
  19. ncbi Comparison of mucosal pressures induced by cuffs of different airway devices
    Herbert Ulrich-Pur
    Intensive Care Unit 13i2, Department of Internal Medicine I, Medical University Vienna, Austria
    Anesthesiology 104:933-8. 2006
    ..The aim of this study was to compare pressures exerted on the pharyngeal, tracheal, and esophageal mucosa by different devices designed for securing the patient's airways...
  20. doi Brief report: tracheal intubation using the Bonfils intubation fibrescope or direct laryngoscopy for patients with a simulated difficult airway
    Christian Byhahn
    Department of Anesthesiology, Intensive Care Medicine, and Pain Management, J W Goethe University Medical School, Frankfurt M, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Can J Anaesth 55:232-7. 2008
    ..We tested the hypothesis that, with the BIF compared to direct laryngoscopy, the rate of failed endotracheal intubation could be reduced in patients with a difficult airway, simulated by means of a rigid cervical immobilization collar...
  21. ncbi The Airtraq as a rescue airway device following failed direct laryngoscopy: a case series
    C H Maharaj
    Department of Anaesthesia, Clinical Sciences Institute, National Centre for Biomedical Engineering Sciences, National University of Ireland, Galway, Ireland
    Anaesthesia 62:598-601. 2007
    ..In contrast, with the Airtraq device, each patient's trachea was successfully intubated on the first attempt. This report underlines the utility of the Airtraq device in these patients...
  22. ncbi Where's the tube? Evaluation of hand-held ultrasound in confirming endotracheal tube placement
    Rosaleen Chun
    Department of Anesthesia, Foothills Medical Centre, Calgary, Alberta, Canada
    Prehosp Disaster Med 19:366-9. 2004
    ..Thoracic sonography, previously utilized to detect pneumothoraces, has not been tested to assess ETT placement...
  23. ncbi Guidelines for emergency tracheal intubation immediately after traumatic injury
    C Michael Dunham
    St Elizabeth Health Center, Youngstown, Ohio 44501 1790, USA
    J Trauma 55:162-79. 2003
  24. ncbi Impact of unplanned extubation and reintubation after weaning on nosocomial pneumonia risk in the intensive care unit: a prospective multicenter study
    Arnaud de Lassence
    Medical ICU, Avicenne Hospital, Bobigny, France
    Anesthesiology 97:148-56. 2002
    ....
  25. pmc Prehospital rapid sequence induction by emergency physicians: is it safe?
    C A Mackay
    Helicopter Emergency Medical Service, Royal London Hospital, Whitechapel
    Emerg Med J 18:20-4. 2001
    ..To determine if there were differences in practice or intubation mishap rate between anaesthetists and accident and emergency physicians performing rapid sequence induction of anaesthesia (RSI) in the prehospital setting...
  26. ncbi Measurement of tracheal tube cuff pressure in critical care
    D Vyas
    Department of Anaesthesia, Leeds General Infirmary, UK
    Anaesthesia 57:275-7. 2002
    ..Critically ill patients are particularly vulnerable to tracheal injury due to prolonged intubation. We suggest that cuff pressures should be measured regularly...
  27. ncbi A comparison of a left-sided Broncho-Cath with the torque control blocker univent and the wire-guided blocker
    Javier H Campos
    Department of Anesthesia, University of Iowa Health Care, Iowa City 52242, USA
    Anesth Analg 96:283-9, table of contents. 2003
    ..For elective thoracic surgical cases, once the lung was isolated, the management seemed to be similar for all three tube groups...
  28. doi Evaluation of the Airtraq and Macintosh laryngoscopes in patients at increased risk for difficult tracheal intubation
    C H Maharaj
    Department of Anaesthesia and Intensive Care Medicine, Galway University Hospitals, Galway, Ireland
    Anaesthesia 63:182-8. 2008
    ..4 (0.8) vs 7.7 (3.0)). Tracheal intubation with the Airtraq also reduced the degree of haemodynamic stimulation and minor trauma compared to the Macintosh laryngoscope...
  29. ncbi The effectiveness of premedication for endotracheal intubation in mechanically ventilated neonates. A systematic review
    Vibhuti Shah
    Department of Paediatrics, Mount Sinai Hospital, Faculty of Medicine, University of Toronto, 600 University Avenue, Toronto, ON M5G 1X5, Canada
    Clin Perinatol 29:535-54. 2002
    ..Adequately skilled staff who have a full understanding of the potential benefits and harms of the interventions used should perform intubation and the administration of premedication in neonates...
  30. pmc VEGF is upregulated by hypoxia-induced mitogenic factor via the PI-3K/Akt-NF-kappaB signaling pathway
    Qiangsong Tong
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Respir Res 7:37. 2006
    ..In this study, we investigated the mechanisms which HIMF enhances expression of vascular endothelial growth factor (VEGF) in lung tissues and epithelial cells...
  31. ncbi The influence of endotracheal tube leak on the assessment of respiratory function in ventilated children
    E Main
    Physiotherapy Department, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1 N 3JH, UK
    Intensive Care Med 27:1788-97. 2001
    ..This study aimed to assess the influence of tracheal tube leak on measurements of C(rs), R(rs) and expired tidal volume (V(TE)) in ventilated children in order to establish when such measurements were reliable in this population...
  32. ncbi An update on bronchial blockers during lung separation techniques in adults
    Javier H Campos
    Department of Anesthesia, University of Iowa Health Care, Iowa City, Iowa 52242 1079, USA
    Anesth Analg 97:1266-74. 2003
    ..The current use of bronchial blockers, supported by scientific evidence, dictates that bronchial blockers should be available in any service that performs lung separation techniques...
  33. ncbi A randomized study assessing the systematic search for maxillary sinusitis in nasotracheally mechanically ventilated patients. Influence of nosocomial maxillary sinusitis on the occurrence of ventilator-associated pneumonia
    L Holzapfel
    Service de Réanimation et Service de Bactériologie, Centre Hospitalier, Bourg en Bresse and Département de Biostastistique et Informatique Médicale, Hopital Saint Louis, Paris, France
    Am J Respir Crit Care Med 159:695-701. 1999
    ..The effect on mortality should be confirmed...
  34. ncbi The out-of-hospital esophageal and endobronchial intubations performed by emergency physicians
    Arnd Timmermann
    Department of Anesthesiology, Emergency and Intensive Care Medicine, Georg August University, Goettingen, Germany
    Anesth Analg 104:619-23. 2007
    ..Rapid establishment of a patent airway in ill or injured patients is a priority for prehospital rescue personnel. Out-of-hospital tracheal intubation can be challenging. Unrecognized esophageal intubation is a clinical disaster...
  35. pmc Prehospital tracheal intubation in severely injured patients: a Danish observational study
    Erika Frischknecht Christensen
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Aarhus, Aarhus 8000, Denmark
    BMJ 327:533-4. 2003
  36. ncbi A comparison of tracheal intubation using the Airtraq or the Macintosh laryngoscope in routine airway management: A randomised, controlled clinical trial
    C H Maharaj
    Department of Anaesthesia, University College Hospital, Galway, Ireland
    Anaesthesia 61:1093-9. 2006
    ..Tracheal intubation with the Airtraq resulted in less alterations in heart rate. These findings demonstrate the utility of the Airtraq laryngoscope for tracheal intubation in low risk patients...
  37. ncbi Energy balance in the intubated human airway is an indicator of optimal gas conditioning
    Stuart N Ryan
    Fisher and Paykel Healthcare, Panmure, Auckland, New Zealand
    Crit Care Med 30:355-61. 2002
    ..The aim of this study was to determine the inspired gas condition that was thermodynamically neutral to the airway of intubated patients, and also examine the contribution of the endotracheal tube to airway heat and water balance...
  38. ncbi A prospective, randomized comparison of an in-line heat moisture exchange filter and heated wire humidifiers: rates of ventilator-associated early-onset (community-acquired) or late-onset (hospital-acquired) pneumonia and incidence of endotracheal tube oc
    O C Kirton
    Department of Surgery, University of Miami School of Medicine, and the Ryder Trauma Center, Jackson Memorial Hospital, Fla 33101, USA
    Chest 112:1055-9. 1997
    ..Englewood, Colo) in the mechanical ventilator circuit on the incidence of ventilator-associated pneumonia (VAP) and the rate of endotracheal tube occlusion...
  39. ncbi Predicting difficult intubation--worthwhile exercise or pointless ritual?
    S M Yentis
    Anaesthesia 57:105-9. 2002
  40. ncbi Use of the Airtraq laryngoscope in a model of difficult intubation by prehospital providers not previously trained in laryngoscopy
    M Woollard
    School of Biomedical Sciences, Charles Sturt University, Bathurst, New South Wales, Australia
    Anaesthesia 62:1061-5. 2007
    ..Users evaluated it as easy to use and achieved intubation within an acceptable breath-to-breath interval...
  41. ncbi Airway Scope: initial clinical experience with novice personnel
    Yoshihiro Hirabayashi
    Can J Anaesth 54:160-1. 2007
  42. ncbi Early clinical experience with a new videolaryngoscope (GlideScope) in 728 patients
    Richard M Cooper
    Department of Anesthesia and Pain Management, Toronto General Hospital, 200 Elizabeth Street, 3 EN 421, Toronto, Ontario M5G 2C4, Canada
    Can J Anaesth 52:191-8. 2005
    ..To evaluate a new videolaryngoscope and assess its ability to provide laryngeal exposure and facilitate intubation...
  43. ncbi Noninvasive positive pressure ventilation reverses acute respiratory failure in select "do-not-intubate" patients
    Guilherme Schettino
    Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Crit Care Med 33:1976-82. 2005
    ..To determine the outcome from the use of noninvasive positive pressure ventilation (NPPV) in "do-not-intubate" (DNI) patients in acute respiratory failure...
  44. ncbi Preoxygenation in critically ill patients requiring emergency tracheal intubation
    Thomas C Mort
    Surgical ICU, Hartford Hospital, Anesthesiology Surgery, University of Connecticut School of Medicine, USA
    Crit Care Med 33:2672-5. 2005
    ..To determine the effectiveness of preoxygenation with 100% oxygen in the critically ill patient in preparation for emergency tracheal intubation...
  45. ncbi Description and first clinical application of AirWay Scope for tracheal intubation
    Jun ichi Koyama
    Department of Neurosurgery, Shinshu University School of Medicine, Asahi, Matsumoto, Japan
    J Neurosurg Anesthesiol 18:247-50. 2006
    ..Here, we report the first clinical application of this system and describe potential advantages of the apparatus...
  46. ncbi Impact of humidification systems on ventilator-associated pneumonia: a randomized multicenter trial
    Jean Claude Lacherade
    Medical Unit, Henri Mondor Hospital, Creteil, France
    Am J Respir Crit Care Med 172:1276-82. 2005
    ....
  47. ncbi Effect of out-of-hospital pediatric endotracheal intubation on survival and neurological outcome: a controlled clinical trial
    M Gausche
    Department of Emergency Medicine, Harbor UCLA Medical Center, and Harbor UCLA Research and Education Institute, Torrance, Calif 90509, USA
    JAMA 283:783-90. 2000
    ..Endotracheal intubation (ETI) is widely used for airway management of children in the out-of-hospital setting, despite a lack of controlled trials demonstrating a positive effect on survival or neurological outcome...
  48. ncbi Management of the difficult airway: a closed claims analysis
    Gene N Peterson
    Department of Anesthesiology, University of Washington, Seattle 98195 6540, USA
    Anesthesiology 103:33-9. 2005
    ..The purpose of this study was to identify the patterns of liability associated with malpractice claims arising from management of the difficult airway...
  49. ncbi Effects of open endotracheal suction on lung volume in infants receiving HFOV
    D G Tingay
    Department of Neonatology, Royal Children s Hospital, Flemington Rd, 3052, Parkville, Vic, Australia
    Intensive Care Med 33:689-93. 2007
    ..To describe the pattern and magnitude of lung volume change during open endotracheal tube (ETT) suction in infants receiving high-frequency oscillatory ventilation (HFOV)...
  50. ncbi Airway management in adults after cervical spine trauma
    Edward T Crosby
    Department of Anesthesiology, University of Ottawa, Ontario, Canada
    Anesthesiology 104:1293-318. 2006
    ..There are no outcome data that would support a recommendation for a particular practice option for airway management; a number of options seem appropriate and acceptable...
  51. ncbi Paramedic versus emergency physician emergency medical service: role of the anaesthesiologist and the European versus the Anglo-American concept
    Arnd Timmermann
    Department of Anaesthesiology, Emergency and Intensive Care Medicine, Georg August University, Goettingen, Germany
    Curr Opin Anaesthesiol 21:222-7. 2008
    ....
  52. ncbi Identification of endotracheal tube malpositions using computerized analysis of breath sounds via electronic stethoscopes
    Christopher J O'Connor
    Department of Anesthesiology, Rush Medical College at Rush University Medical Center, 1653 W Congress Parkway, Chicago, IL 60612, USA
    Anesth Analg 101:735-9. 2005
    ....
  53. pmc Tracheal stenosis aftertracheostomy or intubation: review with special regard to cause and management
    Alpay Sarper
    Department of Thoracic Surgery, Akdeniz University Medical School, Antalya, Turkey
    Tex Heart Inst J 32:154-8. 2005
    ..Management of infraglottic stenosis is difficult, particularly when there is a large laryngeal defect or when there have been previous surgical attempts at the same site...
  54. ncbi Acute functional enhancement of circulatory neutrophils after intratracheal instillation with diesel exhaust particles in rats
    Syunji Yokota
    Laboratory of Toxicology, Hatano Research Institute, Food and Drug Safety Center, Kanagawa, Japan
    Inhal Toxicol 17:671-9. 2005
    ..These results suggest that IT instillation of DEP enhances systemic oxidative stress by increasing neutrophil count and ORP in the acute period...
  55. ncbi Risk factors for adult laryngotracheal stenosis: a review of 74 cases
    Yekaterina Koshkareva
    Dept of Otolaryngology Head and Neck Surgery, Temple University School of Medicine, 3400 N Broad St, Kresge West 102, Philadelphia, PA 19140, USA
    Ann Otol Rhinol Laryngol 116:206-10. 2007
    ..We sought to identify risk factors for and review our experience in the management of adult acquired laryngotracheal stenosis (LTS) at an academic urban medical center...
  56. pmc Determinants of the cuff-leak test: a physiological study
    George Prinianakis
    Intensive Care Medicine Department, University of Crete, University Hospital of Heraklion, Heraklion, Crete, Greece
    Crit Care 9:R24-31. 2005
    ....
  57. pmc Effects of steroids on reintubation and post-extubation stridor in adults: meta-analysis of randomised controlled trials
    Samir Jaber
    Department of Anaesthesiology and Critical Care, University Saint Eloi Hospital, France
    Crit Care 13:R49. 2009
    ..The efficacy of steroid administration before planned tracheal extubation in critical care patients remains controversial with respect to the selection of patients most likely to benefit from this treatment...
  58. ncbi The Thai Anesthesia Incident Monitoring Study (Thai AIMS) of endobronchial intubation: an analysis of 1996 incident reports
    Krairerk Sintavanuruk
    Department of Anesthesiology, Charoenkrung Pracharak Hospital, Bangkok 10120, Thailand
    J Med Assoc Thai 91:1854-60. 2008
    ..To analyze the clinical course, outcomes, contributing factor, corrective and preventive strategies of accidental endobroncheal intubation (EBI) in the Thai Anesthesia Incident Monitoring Study (Thai AIMS)...
  59. ncbi Prognostic factors in laryngotracheal injury following intubation and/or tracheotomy in ICU patients
    E Esteller-Moré
    ENT Department, Hospital General de Catalunya, Cugat del Vallés, Barcelona, Spain
    Eur Arch Otorhinolaryngol 262:880-3. 2005
    ..Consequently, it is essential to establish a time limit to perform tracheotomy in ICU patients. Such timing should be adapted to each patient and pathology...
  60. ncbi Should EMS-paramedics perform paediatric tracheal intubation in the field?
    Bastiaan M Gerritse
    Department of Anaesthesiology, Amphia Hospital, Postbus 90158, 4800 RK Breda, The Netherlands
    Resuscitation 79:225-9. 2008
    ..To determine the incidence and success rate of out-of-hospital tracheal intubation (TI) and ventilation of children, taking account of the type of healthcare provider involved...
  61. ncbi Management of benign stenoses of the large airways in the university hospital in Prague, Czech Republic, in 1998-2003
    Miloslav Marel
    Pulmonary Department of the 1st Medical Faculty, Charles University, Katerinska 19, Prague 2, 120 00 Czech Republic
    Respiration 72:622-8. 2005
    ..Clinically significant benign stenoses of the large airways develop in about 1% of patients after intubation. The management of benign stenoses is not unified around the world, nor are there any accepted methods for their screening...
  62. ncbi Intravenous injection of methylprednisolone reduces the incidence of postextubation stridor in intensive care unit patients
    Kuo Chen Cheng
    Department of Intensive Care Medicine, Chi Mei Medical Center, Tainan, Taiwan
    Crit Care Med 34:1345-50. 2006
    ..To determine whether treatment with corticosteroids decreases the incidence of postextubation airway obstruction in an adult intensive care unit...
  63. doi [Field 5. Safety practices procedures for mechanical ventilation. French-speaking Society of Intensive Care. French Society of Anesthesia and Resuscitation]
    C Girault
    Service de réanimation médicale et groupe de recherche sur le handicap ventilatoire, UPRES EA 3830 IFRMP 23, UFR de Medecine et de Pharmacie, Hopital Charles Nicolle, CHU Hôpitaux de Rouen, Rouen Cedex, France
    Ann Fr Anesth Reanim 27:e77-89. 2008
    ..The main objective of safety practices described in this chapter is to prevent or avoid the main risks due to invasive mechanical ventilation...
  64. ncbi Intubating conditions and hemodynamic effects of etomidate for rapid sequence intubation in the emergency department: an observational cohort study
    Peter J Zed
    Clinical Service Unit, Vancouver General Hospital, Vancouver, British Columbia, Canada
    Acad Emerg Med 13:378-83. 2006
    ..To describe and analyze the intubating conditions and hemodynamic effects of etomidate in patients undergoing rapid sequence intubation (RSI) in the emergency department...
  65. ncbi Proper insertion depth of endotracheal tubes in adults by topographic landmarks measurements
    Shmuel Evron
    Department of Anesthesia, The Edith Wolfson Medical Center, Holon 58100, Israel
    J Clin Anesth 19:15-9. 2007
    ..To evaluate a new method of endotracheal tube (ETT) positioning relative to carina, based on external topographic landmarks...
  66. doi Outcomes after out-of-hospital endotracheal intubation errors
    Henry E Wang
    Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Resuscitation 80:50-5. 2009
    ..We sought to evaluate the association between three key out-of-hospital endotracheal intubation (ETI) errors and patient outcomes...
  67. ncbi Learning and performance of tracheal intubation by novice personnel: a comparison of the Airtraq and Macintosh laryngoscope
    C H Maharaj
    Department of Anaesthesia, University College Hospital Galway, Ireland
    Anaesthesia 61:671-7. 2006
    ..The Airtraq device showed a rapid learning curve and the students found it significantly easier to use. The Airtraq appears to be a superior device for novice personnel to acquire the skills of tracheal intubation...
  68. ncbi The effect of extubation failure on outcome in a multidisciplinary Australian intensive care unit
    John R Gowardman
    Intensive Care Unit, The Canberra Hospital, Canberra, ACT, Australia
    Crit Care Resusc 8:328-33. 2006
    ..A reported association between extubation failure (EF) and increased hospital length of stay and mortality led us to assess outcome of EF in an Australian intensive care unit...
  69. ncbi Prehospital airway management: a prospective evaluation of anaesthesia trained emergency physicians
    Arnd Timmermann
    Department of Anesthesiology, Emergency and Intensive Care and Medicine, Georg August University of Goettingen, Germany
    Resuscitation 70:179-85. 2006
    ..To determine the characteristics of prehospital tracheal intubation and the incidence of difficult-to-manage airways in out-of-hospital patients managed by emergency medicine physicians with anaesthesia training...
  70. ncbi Benefits and risks of success or failure of noninvasive ventilation
    Alexandre Demoule
    Service de Reanimation Medicale, AP HP, Hopital Henri Mondor, 51 Av du Mal de Lattre de Tassigny, 94000, Creteil, France
    Intensive Care Med 32:1756-65. 2006
    ..The impact of NIV failure and success was compared between de novo and CPE or AOC after adjustment for disease severity...
  71. ncbi Airway intubation in a helicopter cabin: video vs. direct laryngoscopy in manikins
    Benjamin Berg
    Telehealth Research Institute, University of Hawaii, John A Burns School of Medicine, Honolulu, HI 96813, USA
    Aviat Space Environ Med 80:820-3. 2009
    ..An alternative method is video laryngoscopy (VID) that displays magnified images of the glottic opening on a video monitor and allows intubation despite nonstandard positioning...
  72. ncbi Estimating the population incidence of adult post-intubation laryngotracheal stenosis
    S A R Nouraei
    Clin Otolaryngol 32:411-2. 2007
  73. ncbi A chart of failure risk for noninvasive ventilation in patients with COPD exacerbation
    M Confalonieri
    S C Pneumologia, Ospedale di Cattinara, Strada di Fiume, 447, I 34100 Trieste, Italy
    Eur Respir J 25:348-55. 2005
    ....
  74. ncbi Endotracheal intracuff pressures in the ED and prehospital setting: is there a problem?
    James E Svenson
    Section of Emergency Medicine, University of Wisconsin, Madison, WI 53792, USA
    Am J Emerg Med 25:53-6. 2007
    ..The time spent in these settings may be long enough for pressure-induced tracheal mucosal injury to occur. The purpose of this study is to assess cuff pressures in intubated patients before aeromedical transport...
  75. ncbi An in vitro study of the compliance of paediatric tracheal tube cuffs and tracheal wall pressure
    V Bernet
    Department of Neonatology and Intensive Care Medicine, University Children s Hospital, Zurich, Switzerland
    Anaesthesia 61:978-83. 2006
    ....
  76. ncbi Risk factors for extubation failure in patients following a successful spontaneous breathing trial
    Fernando Frutos-Vivar
    Intensive Care Unit, Hospital Universitario de Getafe, Carretera de Toledo Km 12, 500, 28905 Getafe, Madrid, Spain
    Chest 130:1664-71. 2006
    ..To assess the factors associated with reintubation in patients who had successfully passed a spontaneous breathing trial...
  77. ncbi Management of post-intubation tracheal stenoses using the endoscopic approach
    S Cavaliere
    Unit of Respiratory Endoscopy and Laser Therapy, Spedali Civili of Brescia, Italy
    Monaldi Arch Chest Dis 67:73-80. 2007
    ..Over 600 post-intubation tracheal stenoses have been treated in our centre since 1982: the aim of this study was to determine the safety and efficacy of our endoscopic approach...
  78. ncbi Evaluation of the Airway Scope, a new video laryngoscope, in tracheal intubation by naive operators: a manikin study
    T Miki
    Department of Anesthesiology and Critical Care Medicine, Yokohama City University, School of Medicine, Yokohama, Japan
    Acta Anaesthesiol Scand 51:1378-81. 2007
    ..The Airway Scope (AWS) is a new video laryngoscope. The purpose of this study was to compare the AWS and Macintosh laryngoscopes with regard to their usefulness for beginners in tracheal intubation...
  79. pmc End tidal carbon dioxide monitoring in prehospital and retrieval medicine: a review
    M J Donald
    Accident and Emergency Department, Ninewells Hospital and Medical School, Dundee DD19SY UK
    Emerg Med J 23:728-30. 2006
    ..The units now available are compact and rugged, with extended battery operating times, which are ideally suited for prehospital use and should be considered as an essential item for advanced airway management...
  80. ncbi Esophageal intubation with indirect clinical tests during emergency tracheal intubation: a report on patient morbidity
    Thomas C Mort
    Department of Anesthesiology, Hartford Hospital, Hartford, CT 06102, USA
    J Clin Anesth 17:255-62. 2005
    ..To determine the consequences of esophageal intubation (EI) when using standard indirect clinical tests to detect endotracheal tube (ETT) placement in the emergency setting outside the operating room (OR)...
  81. ncbi Early and late failure of noninvasive ventilation in chronic obstructive pulmonary disease with acute exacerbation
    P Carratu
    Respiratory Diseases, Department of Clinical Methodology and Medical Surgical Technologies, University of Bari, Bari
    Eur J Clin Invest 35:404-9. 2005
    ....
  82. ncbi The impact of prehospital endotracheal intubation on outcome in moderate to severe traumatic brain injury
    Daniel P Davis
    Department of Emergency Medicine, School of Medicine, University of California, San Diego, 92103 8676, USA
    J Trauma 58:933-9. 2005
    ..Although early intubation to prevent the mortality that accompanies hypoxia is considered the standard of care for severe traumatic brain injury (TBI), the efficacy of this approach remains unproven...
  83. ncbi Prehospital emergency endotracheal intubation using the Bonfils intubation fiberscope
    Christian Byhahn
    Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, J W Goethe University Medical School, Frankfurt, Germany
    Eur J Emerg Med 14:43-6. 2007
    ..The Bonfils intubation fiberscope therefore demonstrated its value as an additional airway management device in both emergency and prehospital settings...
  84. ncbi Should we use etomidate as an induction agent for endotracheal intubation in patients with septic shock?: a critical appraisal
    William L Jackson
    Walter Reed Army Medical Center, Department of Surgery, Critical Care Medicine Service, Building 2, Room 3M12, 6900 Georgia Ave NW, Washington, DC 20307 5001, USA
    Chest 127:1031-8. 2005
    ..The potential role for concomitant empiric steroid replacement and the comparability of alternative induction regimens are also discussed...
  85. ncbi Noninvasive ventilation in hypercapnic acute respiratory failure due to chronic obstructive pulmonary disease vs. other conditions: effectiveness and predictors of failure
    Jason Phua
    Division of Respiratory and Critical Care Medicine, Department of Medicine, National University Hospital, Singapore
    Intensive Care Med 31:533-9. 2005
    ..This study compared the effectiveness of noninvasive ventilation (NIV) and the risk factors for NIV failure in hypercapnic acute respiratory failure (ARF) due to chronic obstructive pulmonary disease (COPD) vs. non-COPD conditions...
  86. ncbi The ProSeal laryngeal mask airway and the laryngeal tube Suction for ventilation in gynaecological patients undergoing laparoscopic surgery
    H Roth
    University Hospital Mannheim, Institute of Anaesthesiology and Intensive Care Medicine, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Manheim, Germany
    Eur J Anaesthesiol 22:117-22. 2005
    ....
  87. ncbi Performance of the PAxpress vs the ProSeal laryngeal mask airway during general anesthesia
    Alexandre Lallo
    Department of Anesthesiology, University of Montreal, CHUM, Hopital Notre Dame, 1560, Sherbrooke East, Montreal, Quebec H2L 4M1, Canada
    Can J Anaesth 54:28-33. 2007
    ..A prospective, randomized study was undertaken to compare the PAx with the ProSeal laryngeal mask airway (PLMA) during anesthesia with positive pressure ventilation...
  88. pmc The intubating laryngeal mask: is there a role for paramedics?
    Robert Menzies
    Northampton General Hospital, Cliftonville, Northampton NN1 5BD, UK
    Emerg Med J 24:198-9. 2007
    ..To compare the ability of UK paramedics to intubate a simulated difficult airway using a Mackintosh laryngoscope versus an intubating laryngeal mask airway (ILMA)...
  89. ncbi Predicting difficult and impossible mask ventilation
    Allan P Reed
    Anesthesiology 107:170; author reply 171-2. 2007
  90. ncbi A comparison of the laryngeal tube-S and Proseal laryngeal mask during outpatient surgical procedures
    F Zand
    Shiraz University of Medical Sciences, Namazi Hospital, Department of Anaesthesiology, Shiraz, Iran
    Eur J Anaesthesiol 24:847-51. 2007
    ..The present investigation compared their performance in a randomized controlled study...
  91. ncbi [Airway management]
    G Schälte
    Klinik fur Anasthesiologie, Universitatsklinikum Aachen, Pauwelsstrasse 30, 52074 Aachen
    Anaesthesist 56:837-55; quiz 856-7. 2007
    ....
  92. doi [Prediction and definition of difficult mask ventilation and difficult intubation: question 1. Société Française d'Anesthésie et de Réanimation]
    P Diemunsch
    Département d Anesthésiologie, Hopital Civil de Strasbourg, 1, Place de l Hopital, 67091 Strasbourg, France
    Ann Fr Anesth Reanim 27:3-14. 2008
  93. ncbi Assessment of manoeuvres required for successful blind tracheal intubation through the PAXpress
    S M Ahmed
    Department of Anaesthesiology, J N Medical College, AMU, Aligarh, India
    Anaesthesia 63:32-5. 2008
    ..Extension' is the predominant adjusting manoeuvre required for blind tracheal intubation, especially when the alignment of the PAXpress to the larynx is poor...
  94. ncbi [Difficult airway-management devices. Establishment and maintenance: question 4. Société Française d'Anesthésie et de Réanimation]
    X Combes
    Service d anesthésie réanimation Samu Smur, Hôpital Henri Mondor AP HP, 51, Avenue du Marechal de Lattre de Tassigny, 94010 Creteil, France
    Ann Fr Anesth Reanim 27:33-40. 2008
  95. ncbi Self-reported changes in attitude and behavior after attending a simulation-aided airway management course
    Sebastian G Russo
    Department of Anesthesiology, Emergency and Intensive Care Medicine, Georg August University, 37075, Gottingen, Germany
    J Clin Anesth 19:517-22. 2007
    ..To evaluate the influence of a simulator-aided course for airway management on participants' daily clinical airway management practice...
  96. ncbi Intubating laryngeal mask as a ventilatory device during percutaneous dilatational tracheostomy: a descriptive study
    U Linstedt
    Department of Anaesthesiology, Intensive Care Medicine, and Pain Therapy, Diako Hospital, Flensburg, Academic Teaching Hospital of the University of Kiel, Germany
    Br J Anaesth 99:912-5. 2007
    ..We report our experience with this method...
  97. ncbi [Airway obstruction after tracheostomy in a neurologically impaired child]
    Mizuho Kawase
    Matsumoto Dental University, Nagano 399 0781
    Masui 57:352-4. 2008
    ..Tracheomalacia can be a cause of sudden difficult ventilation in neurologically impaired children...
  98. ncbi [Which anaesthesia techniques for difficult intubation? Particular situations: question 3. Société Française d'Anesthésie et de Réanimation]
    F Sztark
    Service d anesthésie réanimation 1, Hopital Pellegrin, CHU de Bordeaux, 33076 Bordeaux Cedex, France
    Ann Fr Anesth Reanim 27:26-32. 2008
  99. ncbi Comparison of laryngeal tube with laryngeal mask airway in anaesthetized and paralysed patients
    T S Yildiz
    University of Kocaeli, School of Medicine, Department of Anaesthesiology, Kocaeli, Turkey
    Eur J Anaesthesiol 24:620-5. 2007
    ..The laryngeal tube is a relatively new supraglottic airway device for airway management. We compared the new version of the laryngeal tube with the laryngeal mask...
  100. ncbi Montgomery T-tube: anesthetic management
    Sanjay Agrawal
    Department of Anesthesia, Himalayan Institute of Medical Sciences, Dehradun, 248140 India
    J Clin Anesth 19:135-7. 2007
    ..Safe management of such patients requires careful planning. We describe different techniques of anaesthetic management in two cases of injuries to the throat, for which this tube was inserted as a tracheal stent...
  101. ncbi A prospective, randomized comparison of cobra perilaryngeal airway and laryngeal mask airway unique in pediatric patients
    Peter Szmuk
    Department of Anesthesiology, University of Texas Southwestern Medical School and Children s Medical Center at Dallas, 1935, B3304, Motor St, Dallas, TX 75235, USA
    Anesth Analg 107:1523-30. 2008
    ..The Cobra Perilaryngeal Airway (PLA) provides better sealing pressure than the Laryngeal Mask Airway Unique (LMAU) during positive-pressure ventilation in adults. We compared the performance of the CobraPLA and LMAU in infants and children...

Research Grants66

  1. Effect of Out-of-Hospital Endotracheal Intubation Errors
    Henry Wang; Fiscal Year: 2008
    ..These analyses are innovative in the fields of EMS, patient safety and health services research and will help to justify system-wide efforts to reduce errors in this complex procedure. ..
  2. Effect of Paramedic Airway Experience on Patient Outcomes
    Henry Wang; Fiscal Year: 2008
    ..These findings would also confirm this linkage method as a new, powerful tool to evaluate the earliest portion of acute medical care - that begun in the out-of-hospital setting. ..
  3. Effect of Paramedic Airway Experience on Patient Outcomes
    Henry Wang; Fiscal Year: 2007
    ..These findings would also confirm this linkage method as a new, powerful tool to evaluate the earliest portion of acute medical care - that begun in the out-of-hospital setting. [unreadable] [unreadable] [unreadable]..
  4. Effect of Paramedic Airway Experience on Patient Outcomes
    Henry Wang; Fiscal Year: 2008
    ..These findings would also confirm this linkage method as a new,powerful tool to evaluate the earliest portion of acute medical care - that begun inthe out-of-hospital setting. ..
  5. The Effect of Hypertonic Resuscitation for Blunt Trauma
    Eileen Bulger; Fiscal Year: 2004
    ..abstract_text> ..
  6. Hypertonic Modulation of Inflammation following Injury
    Eileen Bulger; Fiscal Year: 2008
    ..The results of these studies will provide valuable information to determine the ultimate therapeutic use of the resuscitation strategy. ..
  7. The Effect of Hypertonic Resuscitation for Blunt Trauma
    Eileen Bulger; Fiscal Year: 2003
    ..abstract_text> ..
  8. The Effect of Hypertonic Resuscitation for Blunt Trauma
    Eileen Bulger; Fiscal Year: 2005
    ..abstract_text> ..
  9. Hypertonic Modulation of Inflammation following Injury
    Eileen Bulger; Fiscal Year: 2009
    ..The results of these studies will provide valuable information to determine the ultimate therapeutic use of the resuscitation strategy. ..
  10. Hypertonic Modulation of Inflammation following Injury
    Eileen M Bulger; Fiscal Year: 2010
    ..The results of these studies will provide valuable information to determine the ultimate therapeutic use of the resuscitation strategy. ..
  11. Hypertonic Modulation of Inflammation following Injury
    Eileen Bulger; Fiscal Year: 2007
    ..The results of these studies will provide valuable information to determine the ultimate therapeutic use of the resuscitation strategy. ..
  12. Bcl-2 and Ca2+ Homeostasis in Cardiac Dysfunction
    Ulrich Schmidt; Fiscal Year: 2006
    ..The ability to modify apoptosis and contractile properties in heart failure would represent an important step towards developing new therapeutic approaches for heart failure. ..
  13. Sleep Apnea and Obesity: Cardiovascular Risk Assessment
    Atul Malhotra; Fiscal Year: 2006
    ..This data may have important implications for the diagnosis and treatment of these abnormalities. ..
  14. PM Induced Altered Regulation of G1 Cyclins in AEC
    Daya Upadhyay; Fiscal Year: 2008
    ..Our proposed work will enable us to understand the molecular and biological basis of pathophysiology of ambient airborne particulate induced lung diseases. ..
  15. Prospective Validation and Cost Analysis of the National Guidelines for Field Tri
    Craig D Newgard; Fiscal Year: 2010
    ....
  16. Mechanisms of anesthesia mediaited neurotoxicity
    Huafeng Wei; Fiscal Year: 2010
    ..Ultimately we hope to develop a strategy to prevent these harmful effects. This research will increase our understanding of general anesthesia-mediated neurotoxicity and make a safer use of inhaled anesthetics to surgical patients. ..
  17. ORAL CARE INTERVENTION IN MECHANICALLY VENTILATED ADULTS
    Cindy Munro; Fiscal Year: 2006
    ..Results of the study have the potential to positively affect patient well-being, morbidity, mortality and health care costs. ..
  18. NEUTROPHIL ACTIVATION IN ACUTE LUNG INJURY
    Edward Abraham; Fiscal Year: 2008
    ....
  19. Volatile anesthetics, calcium homeostasis and apoptosis
    Huafeng Wei; Fiscal Year: 2008
    ..We will examine neuronal apoptosis by histopathology, and learning and cognition change in animals after treatment of isoflurane or sevoflurane. ..
  20. Assessment of Lung function in Mice
    Jason Bates; Fiscal Year: 2008
    ....
  21. The Host Response to Calfactant for Direct Acute Lung Injury in Critically Ill Ch
    Derek Wheeler; Fiscal Year: 2008
    ..Our goal is to determine the genetic factors that may alter the response to surfactant in patients with direct lung injury. ..
  22. NF-kappaB and Innate Immunity in the Lungs
    JOSEPH MIZGERD; Fiscal Year: 2008
    ..Such knowledge will be essential to guiding future studies aiming to manipulate innate immune signaling in order to prevent or treat lung infections. ..
  23. Sleep Apnea and Obesity: Cardiovascular Risk Assessment
    Atul Malhotra; Fiscal Year: 2008
    ..This data may have important implications for the diagnosis and treatment of these abnormalities. ..
  24. Regulation and function of STAT3 during pneumonia
    JOSEPH MIZGERD; Fiscal Year: 2008
    ..Elucidating the regulation and function of IL-6 and STAT3 during pneumonia will provide molecular targets for improving host defense and preventing lung injury in patients with or at risk for lung infections. ..
  25. Hyperbaric O2 Stimulation of Salivary Flow in Radiation -induced Xerostomia
    Michael Martin; Fiscal Year: 2008
    ....
  26. Mechanisms of anesthesia mediaited neurotoxicity
    Huafeng Wei; Fiscal Year: 2008
    ..Ultimately we hope to develop a strategy to prevent these harmful effects. This research will increase our understanding of general anesthesia-mediated neurotoxicity and make a safer use of inhaled anesthetics to surgical patients. ..
  27. Single Motor Unit Genioglossus Recordings to Understand Sleep Apnea Pathogenesis
    Atul Malhotra; Fiscal Year: 2010
    ....
  28. Role of C/EBPalpha in Cytoprotection and Recovery from Lung Injury
    Machiko Ikegami; Fiscal Year: 2010
    ..Furthermore, the molecular mechanisms, in particular the signaling pathways regulating Cebpa, of recombinant human FGF-7 treatment for acute lung injury will be determined. ..
  29. Fluid Therapy and Cerebral Injury in Pediatric Diabetic Ketoacidosis
    NATHAN contact KUPPERMANN; Fiscal Year: 2010
    ..In the proposed study, we plan to compare four different DKA treatment regimens to determine which regimen results in the least risk of brain injury. ..
  30. Cytochrome oxidase inhibition in septic heart
    Richard Levy; Fiscal Year: 2008
    ..Along with preliminary data, this proposal will allow the junior investigator to develop a research career focused on mitochondrial dysfunction, cytopathic hypoxia, and sepsis-associated myocardial depression. ..
  31. Cancer Pain in Elders: Promoting EBPs in Hospices
    Keela Herr; Fiscal Year: 2009
    ..abstract_text> ..
  32. Role of C/EBPalpha in Cytoprotection and Recovery from Lung Injury
    Machiko Ikegami; Fiscal Year: 2009
    ..Furthermore, the molecular mechanisms, in particular the signaling pathways regulating Cebpa, of recombinant human FGF-7 treatment for acute lung injury will be determined. ..
  33. MECHANICS OF ACUTE LUNG INJURY
    Jason Bates; Fiscal Year: 2009
    ..The results of our studies are expected to lead to the design of physiologically-based lung recruitment strategies that can be tailored to the individual patient with ALI. This will set the stage for future clinical trials. ..
  34. Occult Small Vessel Cerebrovascular Disease in High Risk Families
    Paul Nyquist; Fiscal Year: 2009
    ..It is also focused on the genes that may increase the susceptibility to small vessel disease in high risk families with a history of disease. ..
  35. ORAL CARE INTERVENTION IN MECHANICALLY VENTILATED ADULTS
    Cindy Munro; Fiscal Year: 2008
    ..The intervention tested in this project (swabbing the mouth with chlorhexidine before the endotracheal tube is inserted) could reduce the risk of ventilator-associated pneumonia. ..
  36. EXPERIMENTAL THERAPEUTICS IN CRITICAL ILLNESS
    Michael Pinsky; Fiscal Year: 2008
    ..Furthermore, formal research presentations by the trainees will be given biannually to the local research community. ..
  37. PCCM Network: Remedies for Opioid Tolerance & Withdrawal
    KANWALJEET ANAND; Fiscal Year: 2008
    ....
  38. Airway Hyper-responsiveness: from molecule to organ
    Jason Bates; Fiscal Year: 2007
    ..With this approach, the key events in AHR can be identified and targeted for therapeutic intervention. ..
  39. Cancer Pain in Elders: Promoting EBPs in Hospices
    Keela Herr; Fiscal Year: 2005
    ..abstract_text> ..
  40. Quantifying Left Ventricular Ejection Effectiveness
    Michael Pinsky; Fiscal Year: 2005
    ..The ultimate goal of this proposal is to develop and validate an echocardiographic-based algorithm that quantifies LV ejection effectiveness by merging both power and synchrony of contraction into a common metric. ..
  41. Micellar VIP Nanoparticles for Rheumatoid Arthritis
    Israel Rubinstein; Fiscal Year: 2005
    ..abstract_text> ..
  42. ROLE OF SURFACTANT PROTEIN D IN SURFACTANT HOMEOSTASIS
    Machiko Ikegami; Fiscal Year: 2005
    ..The intended studies will provide fundamental insights into the role of SP-D in the protection of the lung, as well as into the basic mechanisms determining surfactant homeostasis. ..
  43. NEUTROPHIL ACTIVATION IN ACUTE LUNG INJURY
    Edward Abraham; Fiscal Year: 2004
    ....
  44. NEUTROPHIL ACTIVATION IN ACUTE LUNG INJURY
    Edward Abraham; Fiscal Year: 2003
    ....
  45. Sleep Apnea and Obesity: Cardiovascular Risk Assessment
    Atul Malhotra; Fiscal Year: 2003
    ..This data may have important implications for the diagnosis and treatment of these abnormalities. ..
  46. Heart Period Variability in Critically Ill VLBW Infants
    Sandra Smith; Fiscal Year: 2002
    ..of heart period power, (2) test the impact of developmental care on heart period power, and (3) develop and test interventions that would promote balance in the low- and high-frequency regions of heart period power ..
  47. NEUTROPHIL ACTIVATION IN ACUTE LUNG INJURY
    Edward Abraham; Fiscal Year: 2002
    ....
  48. PHONATION AND PHONATORY CONTROL IN VOCAL TREMORS
    Marshall Smith; Fiscal Year: 2002
    ..The experimental phase consists of studies of neuromuscular and respiratory input to the larynx. This information about vocal tremor will be applied to model simulations with the use of physiological signals as input model parameters. ..
  49. NEUTROPHIL ACTIVATION IN ACUTE LUNG INJURY
    Edward Abraham; Fiscal Year: 2001
    ....
  50. ROLE OF SURFACTANT PROTEIN D IN SURFACTANT HOMEOSTASIS
    Machiko Ikegami; Fiscal Year: 2000
    ..The goal is to understand the role of SP-D in the cellular and/or structural mechanisms involved in independent regulation of phospholipid and surfactant protein homeostasis. ..
  51. Urokinase, Neutrophil Activation and Acute Lung Injury
    Edward Abraham; Fiscal Year: 2006
    ..abstract_text> ..
  52. ALCOHOL ABUSE & DEPENDENCE IN TRAUMA PATIENTS
    Carl Soderstrom; Fiscal Year: 1993
    ..Also, patient driving records will be examined to determine if information obtained from them may be used to help profile the alcoholic trauma patient...
  53. Assessment of Lung function in Mice
    Jason Bates; Fiscal Year: 2007
    ....
  54. Strategies for Airway Management & Prevention Endotracheal Tube Cuff Intervention
    MARY SOLE; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  55. Micellar VIP Nanoparticles for Rheumatoid Arthritis
    Israel Rubinstein; Fiscal Year: 2007
    ..abstract_text> ..
  56. Volatile anesthetics, calcium homeostasis and apoptosis
    Huafeng Wei; Fiscal Year: 2007
    ..We will examine neuronal apoptosis by histopathology, and learning and cognition change in animals after treatment of isoflurane or sevoflurane. ..
  57. PCCM Network: Remedies for Opioid Tolerance & Withdrawal
    KANWALJEET ANAND; Fiscal Year: 2007
    ....
  58. Assessment of Lung function in Mice
    Jason Bates; Fiscal Year: 2006
    ....
  59. Quantifying Left Ventricular Ejection Effectiveness
    Michael Pinsky; Fiscal Year: 2006
    ..The ultimate goal of this proposal is to develop and validate an echocardiographic-based algorithm that quantifies LV ejection effectiveness by merging both power and synchrony of contraction into a common metric. ..
  60. Cancer Pain in Elders: Promoting EBPs in Hospices
    Keela Herr; Fiscal Year: 2006
    ..abstract_text> ..
  61. Micellar VIP Nanoparticles for Rheumatoid Arthritis
    Israel Rubinstein; Fiscal Year: 2006
    ..abstract_text> ..
  62. Validation of the NIH Stroke Scale in Children
    Rebecca Ichord; Fiscal Year: 2006
    ..These observations, and the availability of a simple valid clinical stroke scale for children, will be important for planning and conducting future clinical trials and outcome studies for childhood stroke. [unreadable] [unreadable]..
  63. Red Blood Cells, Nitric Oxide and Pulmonary Circulation
    Steven Deem; Fiscal Year: 2008
    ..abstract_text> ..
  64. HYPOXIC PULMONARY VASOCANSTRICTION AND RED BLOOD CELLS
    Steven Deem; Fiscal Year: 2002
    ....
  65. Red Blood Cells, Nitric Oxide and Pulmonary Circulation
    Steven Deem; Fiscal Year: 2007
    ..abstract_text> ..
  66. Electrode Array Reanimation of the Paralyzed Larynx
    Marshall Smith; Fiscal Year: 2006
    ..Nerve samples will be harvested and studied to examine the effects of the implanted array on RLN fibers. [unreadable] [unreadable]..