equipment design


Top Publications

  1. pmc Lensfree microscopy on a cellphone
    Derek Tseng
    UCLA Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 10:1787-92. 2010
  2. ncbi Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography
    Johannes F de Boer
    Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom Street, BAR 724, Boston, Massachusetts 02114, USA
    Opt Lett 28:2067-9. 2003
  3. ncbi ZnO nanowire UV photodetectors with high internal gain
    C Soci
    Department of Electrical and Computer Engineering, Jacobs School of Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093 0407, USA
    Nano Lett 7:1003-9. 2007
  4. ncbi Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging
    Hao F Zhang
    Optical Imaging Laboratory, Department of Biomedical Engineering, Texas A and M University, 3120 TAMU, College Station, Texas 77843 3120, USA
    Nat Biotechnol 24:848-51. 2006
  5. ncbi A triaxial accelerometer and portable data processing unit for the assessment of daily physical activity
    C V Bouten
    University of Technology, Division of Computational and Experimental Mechanics, Eindhoven, The Netherlands
    IEEE Trans Biomed Eng 44:136-47. 1997
  6. pmc An integrative structural health monitoring system for the local/global responses of a large-scale irregular building under construction
    Hyo Seon Park
    Department of Architectural Engineering, Yonsei University, Seoul, Korea
    Sensors (Basel) 13:9085-103. 2013
  7. pmc Ultrahigh speed spectral / Fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second
    Benjamin Potsaid
    Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Opt Express 16:15149-69. 2008
  8. ncbi Implementation of a real-time human movement classifier using a triaxial accelerometer for ambulatory monitoring
    Dean M Karantonis
    Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia
    IEEE Trans Inf Technol Biomed 10:156-67. 2006
  9. ncbi Stretchable, porous, and conductive energy textiles
    Liangbing Hu
    Department of Materials Science and Engineering, Stanford University, Stanford, California 94305, USA
    Nano Lett 10:708-14. 2010
  10. ncbi Gait analysis using a shoe-integrated wireless sensor system
    Stacy J Morris Bamberg
    Massachusetts Institute of Technology MIT, Cambridge, MA 02139, USA
    IEEE Trans Inf Technol Biomed 12:413-23. 2008

Detail Information

Publications370 found, 100 shown here

  1. pmc Lensfree microscopy on a cellphone
    Derek Tseng
    UCLA Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 10:1787-92. 2010
    ..We report the performance of this lensfree cellphone microscope by imaging various sized micro-particles, as well as red blood cells, white blood cells, platelets and a waterborne parasite (Giardia lamblia)...
  2. ncbi Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography
    Johannes F de Boer
    Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom Street, BAR 724, Boston, Massachusetts 02114, USA
    Opt Lett 28:2067-9. 2003
    ..A significant SNR gain of several hundredfold is found for acquisition in the spectral domain. The SNR benefit is demonstrated experimentally in a hybrid time-domain-spectral-domain OCT system...
  3. ncbi ZnO nanowire UV photodetectors with high internal gain
    C Soci
    Department of Electrical and Computer Engineering, Jacobs School of Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093 0407, USA
    Nano Lett 7:1003-9. 2007
    ..The high gain and low power consumption of NW photodetectors promise a new generation of phototransistors for applications such as sensing, imaging, and intrachip optical interconnects...
  4. ncbi Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging
    Hao F Zhang
    Optical Imaging Laboratory, Department of Biomedical Engineering, Texas A and M University, 3120 TAMU, College Station, Texas 77843 3120, USA
    Nat Biotechnol 24:848-51. 2006
    ..fPAM is demonstrated with in vivo imaging of angiogenesis, melanoma, hemoglobin oxygen saturation (sO2) of single vessels in animals and total hemoglobin concentration in humans...
  5. ncbi A triaxial accelerometer and portable data processing unit for the assessment of daily physical activity
    C V Bouten
    University of Technology, Division of Computational and Experimental Mechanics, Eindhoven, The Netherlands
    IEEE Trans Biomed Eng 44:136-47. 1997
    ..The validity of the system for the assessment of normal daily physical activity and specific activities outside the laboratory should be studied in free-living subjects...
  6. pmc An integrative structural health monitoring system for the local/global responses of a large-scale irregular building under construction
    Hyo Seon Park
    Department of Architectural Engineering, Yonsei University, Seoul, Korea
    Sensors (Basel) 13:9085-103. 2013
  7. pmc Ultrahigh speed spectral / Fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second
    Benjamin Potsaid
    Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Opt Express 16:15149-69. 2008
  8. ncbi Implementation of a real-time human movement classifier using a triaxial accelerometer for ambulatory monitoring
    Dean M Karantonis
    Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia
    IEEE Trans Inf Technol Biomed 10:156-67. 2006
    ..3% accuracy), and detection of possible falls was made with 95.6% accuracy. Results demonstrate the feasibility of implementing an accelerometry-based, real-time movement classifier using embedded intelligence...
  9. ncbi Stretchable, porous, and conductive energy textiles
    Liangbing Hu
    Department of Materials Science and Engineering, Stanford University, Stanford, California 94305, USA
    Nano Lett 10:708-14. 2010
    ..These highly conductive textiles can provide new design opportunities for wearable electronics and energy storage applications...
  10. ncbi Gait analysis using a shoe-integrated wireless sensor system
    Stacy J Morris Bamberg
    Massachusetts Institute of Technology MIT, Cambridge, MA 02139, USA
    IEEE Trans Inf Technol Biomed 12:413-23. 2008
    ..The GaitShoe proved highly capable of detecting heel-strike and toe-off, as well as estimating foot orientation and position, inter alia...
  11. ncbi Ambulatory system for human motion analysis using a kinematic sensor: monitoring of daily physical activity in the elderly
    Bijan Najafi
    Swiss Federal Institute of Technology Lausanne, Institute for Biomedical Engineering, Laboratory of Motion Analysis and Measurement, 1015 Lausanne, Switzerland
    IEEE Trans Biomed Eng 50:711-23. 2003
    ..9% for "standing + walking," 4.1% for sitting, and 0.3% for lying. Finally, overall symmetric mean average errors were 12% for "standing + walking," 8.2% for sitting, and 1.3% for lying...
  12. ncbi Deep tissue multiphoton microscopy using longer wavelength excitation
    Demirhan Kobat
    School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA
    Opt Express 17:13354-64. 2009
    ..An imaging depth of 1 mm can be achieved in in vivo imaging of adult mouse brains at 1280 nm with approximately 1-nJ pulse energy at the sample surface. Blood flow speed measurements at a depth of 900 mum are performed...
  13. ncbi Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range
    Michalina Gora
    Institute of Physics, Nicolaus Copernicus University, ul Grudziadzka 5 7, PL 87 100 Torun, Poland
    Opt Express 17:14880-94. 2009
    ..Additionally, a volumetric and real time reconstruction of dynamic processes, like pupillary reaction to light stimulus or blink-induced contact lens movements are demonstrated...
  14. ncbi Natural orifice translumenal endoscopic surgery: a critical review
    Jonathan P Pearl
    Department of Surgery, National Naval Medical Center, Bethesda, MD, USA
    J Gastrointest Surg 12:1293-300. 2008
    ..The zeal for NOTES should not take precedence over the welfare of the patient...
  15. ncbi Transumbilical single-port surgery: evolution and current status
    David Canes
    Center for Laparoscopic and Robotic Surgery, Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Eur Urol 54:1020-9. 2008
    ..Within a short span, several clinical reports have emerged in the urologic literature. As this field is poised to move forward, a complete understanding of its evolution and current status is timely...
  16. pmc Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging
    Benjamin J Vakoc
    Wellman Center for Photomedicine, Department of Dermatology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, USA
    Nat Med 15:1219-23. 2009
  17. ncbi Robot assisted gait training with active leg exoskeleton (ALEX)
    Sai K Banala
    Department of Mechanical Engineering, University of Delaware, Newark, DE 19716, USA
    IEEE Trans Neural Syst Rehabil Eng 17:2-8. 2009
    ..Improvement is seen as an increase in the size of the patients' gait pattern, increased knee and ankle joint excursions and increase in their walking speeds on the treadmill...
  18. ncbi Measurement of stand-sit and sit-stand transitions using a miniature gyroscope and its application in fall risk evaluation in the elderly
    Bijan Najafi
    Swiss Federal Institute of Technology Lausanne, Metrology Laboratory
    IEEE Trans Biomed Eng 49:843-51. 2002
    ..04-0.68 Hz. The system is especially adapted for long-term ambulatory monitoring of elderly people...
  19. ncbi Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomised controlled trial
    William T Abraham
    Ohio State University Heart and Vascular Center, Columbus, OH, USA
    Lancet 377:658-66. 2011
    ..Results of previous studies support the hypothesis that implantable haemodynamic monitoring systems might reduce rates of hospitalisation in patients with heart failure. We undertook a single-blind trial to assess this approach...
  20. ncbi Pedestrian Tracking with shoe-mounted inertial sensors
    Eric Foxlin
    InterSense, USA
    IEEE Comput Graph Appl 25:38-46. 2005
  21. pmc Spatial light interference microscopy (SLIM)
    Zhuo Wang
    Department of Electrical and Computer Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    Opt Express 19:1016-26. 2011
    ..SLIM is implemented as an add-on module to an existing phase contrast microscope, which may prove instrumental in impacting the light microscopy field at a large scale...
  22. ncbi Ambulatory estimation of foot placement during walking using inertial sensors
    H Martin Schepers
    Institute for Biomedical Technology and Technical Medicine MIRA, University of Twente, AE Enschede, The Netherlands
    J Biomech 43:3138-43. 2010
    ..It is concluded that the ambulatory measurement system was able to reliably estimate foot placement during walking...
  23. ncbi Stereotactic high dose fraction radiation therapy of extracranial tumors using an accelerator. Clinical experience of the first thirty-one patients
    H Blomgren
    Department of Oncology, Karolinska Hospital, Stockholm, Sweden
    Acta Oncol 34:861-70. 1995
    ..We observed a local rate of no progressive disease of 80% during a follow-up period of 1.5-38 months. Fifty percent of the tumors decreased in size or disappeared...
  24. ncbi Diffraction phase microscopy for quantifying cell structure and dynamics
    Gabriel Popescu
    George R Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Opt Lett 31:775-7. 2006
    ..The potential of the technique for quantifying nanoscale motions in live cells is demonstrated by experiments on red blood cells...
  25. pmc Mobile phone based clinical microscopy for global health applications
    David N Breslauer
    UCSF UC Berkeley Bioengineering Graduate Group, University of California Berkeley, Berkeley, CA, USA
    PLoS ONE 4:e6320. 2009
  26. pmc Cost-effective and compact wide-field fluorescent imaging on a cell-phone
    Hongying Zhu
    UCLA Electrical Engineering Department, Los Angeles, CA 90095, USA
    Lab Chip 11:315-22. 2011
  27. pmc A method based on multi-sensor data fusion for fault detection of planetary gearboxes
    Yaguo Lei
    State Key Laboratory for Manufacturing Systems Engineering, Xi an Jiaotong University, No 28 Xianning West Road, Xi an 710049, China
    Sensors (Basel) 12:2005-17. 2012
    ..The comparisons between the proposed method and the methods based on individual sensors show that the former achieves much higher accuracies in detecting planetary gearbox faults...
  28. ncbi Hyperspectral confocal microscope
    Michael B Sinclair
    Department 1824, Sandia National Laboratories Mail Stop 1411, Albuquerque, New Mexico 87185, USA
    Appl Opt 45:6283-91. 2006
    ..The architecture of the new microscope is described in detail, and hyperspectral images from several specimens are presented...
  29. ncbi Advances in ultrasound biomicroscopy
    F S Foster
    Sunnybrook Health Science Centre and Department of Medical Biophysics, University of Toronto, Ontario, Canada
    Ultrasound Med Biol 26:1-27. 2000
    ..Ultrasound biomicroscopic studies of mouse embryonic development and tumour biology are presented. Speculation on the continuing evolution of ultrasound biomicroscopy will be discussed...
  30. ncbi An integrated microfluidic system for rapid diagnosis of dengue virus infection
    Yu Fang Lee
    Department of Engineering Science, National Cheng Kung University, Tainan 701, Taiwan
    Biosens Bioelectron 25:745-52. 2009
    ..This integrated system may provide a powerful platform for the rapid diagnosis of dengue virus infection and other types of infectious diseases...
  31. ncbi Review of tissue simulating phantoms for optical spectroscopy, imaging and dosimetry
    Brian W Pogue
    Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, USA
    J Biomed Opt 11:041102. 2006
    ..This review is an attempt to indicate which sets of phantoms are optimal for specific applications, and provide links to studies that characterize main phantom material properties and recipes...
  32. pmc Technology-assisted training of arm-hand skills in stroke: concepts on reacquisition of motor control and therapist guidelines for rehabilitation technology design
    Annick A A Timmermans
    Faculty of Biomedical Technology, Technical University Eindhoven, Eindhoven, The Netherlands
    J Neuroeng Rehabil 6:1. 2009
    ..It is the purpose of this article to identify and review criteria that rehabilitation technology should meet in order to offer arm-hand training to stroke patients, based on recent principles of motor learning...
  33. pmc Jones matrix analysis for a polarization-sensitive optical coherence tomography system using fiber-optic components
    B Hyle Park
    Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Opt Lett 29:2512-4. 2004
    ..The relative importance of diattenuation versus birefringence to angular displacement of Stokes vectors on a Poincaré sphere was quantified...
  34. ncbi Hilbert phase microscopy for investigating fast dynamics in transparent systems
    Takahiro Ikeda
    Hamamatsu Photonics K K, 5000 Hirakuchi, Hamakita, Shizuoka 434 8601, Japan
    Opt Lett 30:1165-7. 2005
  35. ncbi Microfluidic large-scale integration: the evolution of design rules for biological automation
    Jessica Melin
    Department of Bioengineering, Stanford University and Howard Hughes Medical Institute, Stanford, California 94305, USA
    Annu Rev Biophys Biomol Struct 36:213-31. 2007
    ..Several microfluidic components used as building blocks to create effective, complex, and highly integrated microfluidic networks are also highlighted...
  36. ncbi Fabrication of solid-state nanopores with single-nanometre precision
    A J Storm
    Department of Nanoscience, Delft University of Technology, 2628 CJ Delft, The Netherlands
    Nat Mater 2:537-40. 2003
    ..When the electron beam is switched off, the material quenches and retains its shape. This technique dramatically increases the level of control in the fabrication of a wide range of nanodevices...
  37. pmc Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications
    Onur Mudanyali
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 10:1417-28. 2010
  38. ncbi Comparison of Macintosh, Truview EVO2, Glidescope, and Airwayscope laryngoscope use in patients with cervical spine immobilization
    M A Malik
    Department of Anaesthesia, Clinical Sciences Institute, Galway University Hospitals, Galway, Ireland
    Br J Anaesth 101:723-30. 2008
  39. ncbi Design and evaluation of the LOPES exoskeleton robot for interactive gait rehabilitation
    Jan F Veneman
    Institute for Biomedical Technology BMTI, University of Twente, 7500 EA Enschede, The Netherlands
    IEEE Trans Neural Syst Rehabil Eng 15:379-86. 2007
    ..The possibilities and limitations to using the device as gait measurement tool are also shown at the moment position measurements are not accurate enough for inverse-dynamical gait analysis...
  40. ncbi A new 25-gauge instrument system for transconjunctival sutureless vitrectomy surgery
    Gildo Y Fujii
    Microsurgery Advanced Design Laboratory, Doheny Eye Institute, University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA
    Ophthalmology 109:1807-12; discussion 1813. 2002
    ..To introduce and evaluate the infusion and aspiration rates and operative times of the 25-gauge transconjunctival sutureless vitrectomy system (TSV) DESIGN: In vitro experimental and comparative interventional study...
  41. ncbi Quantification of tremor and bradykinesia in Parkinson's disease using a novel ambulatory monitoring system
    Arash Salarian
    Laboratory of Movement Analysis and Measurement, Swiss Federal Institute of Technology, Lausanne EPFL, 1015, Switzerland
    IEEE Trans Biomed Eng 54:313-22. 2007
    ..01) to UPDRS with window sizes as short as 5 min. Our study provides evidence that objective, accurate and simultaneous assessment of tremor and bradykinesia can be achieved in free moving PD patients during their daily activities...
  42. ncbi Practice parameters for the treatment of snoring and Obstructive Sleep Apnea with oral appliances: an update for 2005
    Clete A Kushida
    Stanford University Center of Excellence for Sleep Disorders, CA, USA
    Sleep 29:240-3. 2006
    ..Regular follow up is also needed to assess the patient for signs and symptoms of worsening OSA. Research to define patient characteristics more clearly for OA acceptance, success, and adherence is needed...
  43. pmc An on-chip, multichannel droplet sorter using standing surface acoustic waves
    Sixing Li
    Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA
    Anal Chem 85:5468-74. 2013
  44. ncbi Nanowire active-matrix circuitry for low-voltage macroscale artificial skin
    Kuniharu Takei
    Department of Electrical Engineering and Computer Sciences, University of California at Berkeley, Berkeley, California 94702, USA
    Nat Mater 9:821-6. 2010
    ..5 mm) for over 2,000 bending cycles. This work presents the largest integration of ordered NW-array active components, and demonstrates a model platform for future integration of nanomaterials for practical applications...
  45. pmc The role of the user within the medical device design and development process: medical device manufacturers' perspectives
    Arthur G Money
    Department of Computer Science and Technology, University of Bedfordshire, Park Square, Luton, UK
    BMC Med Inform Decis Mak 11:15. 2011
    ..However, little research has been carried out to explore medical device manufacturers' beliefs and attitudes towards user involvement within this process, or indeed what value they believe can be added by doing so...
  46. ncbi Smart wheelchairs: A literature review
    Richard C Simpson
    Department of Rehabilitation Science and Technology, University of Pittsburgh, Pittsburgh, PA 15238 2887, USA
    J Rehabil Res Dev 42:423-36. 2005
    ..Smart wheelchairs have been the subject of research since the early 1980s and have been developed on four continents. This article presents a summary of the current state of the art and directions for future research...
  47. ncbi Sensing magnetic flux density of artificial neurons with a MEMS device
    Jesus A Tapia
    Instituto de Fisiologia, Benemerita Universidad Autonoma de Puebla, 14 Sur 6301, Col San Manuel, Puebla, Pue, Mexico
    Biomed Microdevices 13:303-13. 2011
    ..Second, the introduced MEMS magnetic field sensor may be used as a prototype to develop new high-resolution biomedical microdevices to sense magnetic fields from cardiac tissue, nerves, spinal cord, or the brain...
  48. ncbi A multi-sample 94 GHz dissolution dynamic-nuclear-polarization system
    Michael Batel
    Physical Chemistry, ETH Zurich, Wolfgang Pauli Strasse 10, 8093 Zurich, Switzerland
    J Magn Reson 214:166-74. 2012
    ..In the initial liquid-state acquisition experiments described here, the polarization was found to be ∼13%, corresponding to an enhancement factor exceeding 16,000 relative to thermal polarization at 9.4 T and ambient temperature...
  49. ncbi Self-assembly-induced formation of high-density silicon oxide memristor nanostructures on graphene and metal electrodes
    Woon Ik Park
    Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology KAIST, 291 Daehak ro, Yuseong Gu, Daejeon 305 701, Republic of Korea
    Nano Lett 12:1235-40. 2012
    ..This approach offers a very convenient pathway to fabricate ultrahigh-density resistive memory devices without relying on high-cost lithography and pattern-transfer processes...
  50. ncbi Compact quantitative optic fiber-based immunoarray biosensor for rapid detection of small analytes
    Feng Long
    Environmental Simulation and Pollution Control State Key Joint Laboratory, Department of Environment Science and Engineering, Tsinghua University, Beijing, 100084, China
    Biosens Bioelectron 26:16-22. 2010
    ..This compact and portable quantitative immunoarray provides an excellent multiple assay platform for clinical and environmental samples...
  51. ncbi Thermo-optic control of dielectric-loaded plasmonic waveguide components
    Jacek Gosciniak
    Institute of Sensors, Signals and Electrotechnics SENSE, University of Southern Denmark, Niels Bohrs Alle 1, Odense M, Denmark
    Opt Express 18:1207-16. 2010
    ..Strong output modulation (> 20%) is demonstrated with MZI- and WRR-based components, and efficient (approximately 30%) rerouting is achieved with DC switches...
  52. ncbi A home-based rehabilitation program for the hemiplegic upper extremity by power-assisted functional electrical stimulation
    Yukihiro Hara
    Department of Rehabilitation Medicine, Nippon Medical School, Chiba Hokusoh Hospital, Inbagun, Japan
    Disabil Rehabil 30:296-304. 2008
    ..To assess the effects of daily power-assisted functional electrical stimulation (FES) home program therapy in chronic stroke...
  53. ncbi Towards an intelligent wheelchair system for users with cerebral palsy
    Luis Montesano
    Department de Informática e Ingeniería de Sistemas, Universidad de Zaragoza, Zaragoza, Spain
    IEEE Trans Neural Syst Rehabil Eng 18:193-202. 2010
    ..The results indicated that the intelligent wheelchair effectively provided mobility and autonomy to the target population...
  54. ncbi Dielectrophoresis-based cell manipulation using electrodes on a reusable printed circuit board
    Kidong Park
    School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN 47907, USA
    Lab Chip 9:2224-9. 2009
  55. pmc Multiple-electrode radiofrequency ablations using Octopus® electrodes in an in vivo porcine liver model
    E S Lee
    Department of Radiology, Seoul NationalUniversity College of Medicine, Seoul, Republic of Korea
    Br J Radiol 85:e609-15. 2012
    ..The objective of this study was to determine the in vivo efficacy of radiofrequency ablation (RFA) in porcine liver using Octopus® electrodes for creating a large coagulation compared with RFA using clustered electrodes...
  56. pmc Improving planetary rover attitude estimation via MEMS sensor characterization
    Javier Hidalgo
    Centro de Automática y Robótica, UPM CSIC, Jose Gutierrez Abascal 2, Madrid 28006, Spain
    Sensors (Basel) 12:2219-35. 2012
    ..The strength of the approach has been verified with representative tests of novel high-grade MEMS inertia sensors and exemplary planetary rover platforms with promising results...
  57. ncbi Gait posture estimation using wearable acceleration and gyro sensors
    Ryo Takeda
    Division of Human Mechanical Systems and Design, Graduate School of Engineering, Hokkaido University, N13 W8, Kita ku, Sapporo 060 8628, Japan
    J Biomech 42:2486-94. 2009
    ..A moving stick figure model of each volunteer was created to visually confirm the walking posture. Further, the knee and ankle joint trajectories in the horizontal plane showed that the left and right legs were bilaterally symmetric...
  58. ncbi [An alternative fixation method for the treatment of unstable distal clavicle fractures: locked distal radius plate]
    Bulent Daglar
    Department of Orthopedics and Traumatology, Ankara Numune Training and Research Hospital, Ankara, Turkey
    Acta Orthop Traumatol Turc 43:324-30. 2009
    ..We evaluated the results of surgical treatment of displaced distal clavicle fractures using locked distal radius plates...
  59. ncbi Inertial sensor-based knee flexion/extension angle estimation
    Glen Cooper
    Centre for Rehabilitation and Human Performance Research, University of Salford, UK
    J Biomech 42:2678-85. 2009
    ..4 degrees for running (5 mph). The joint constraint used in the IMU analysis was derived from the Qualysis data. Limitations of the method, its clinical application and its possible extension are discussed...
  60. pmc Efficacy of two educational interventions about inhalation techniques in patients with chronic obstructive pulmonary disease (COPD). TECEPOC: study protocol for a partially randomized controlled trial (preference trial)
    Francisca Leiva-Fernández
    Family and Community Medicine Teaching Unit of Malaga, Distrito Sanitario Málaga, Malaga, Spain
    Trials 13:64. 2012
    ..The objective of this study is to test the efficacy of two educational interventions to improve the inhalation techniques in patients with Chronic Obstructive Pulmonary Disease (COPD)...
  61. ncbi Study of osteoblastic cells in a microfluidic environment
    E Leclerc
    CNRS UMR 6600, Laboratoire de Biomécanique et génie Biomédical, Universite de Technologie de Compiegne, Centre de Recherche de Royallieu, France
    Biomaterials 27:586-95. 2006
    ..These results are promising for bone cell growth and differentiation as well as future tissue regeneration using larger 3D microfluidic microdevices...
  62. ncbi Systematic measurements of whole-body dose distributions for various treatment machines and delivery techniques in radiation therapy
    Roger A Hälg
    Institute for Radiotherapy, Radiotherapie Hirslanden AG, Aarau, Switzerland
    Med Phys 39:7662-76. 2012
    ..In this study, whole-body dose distributions from typical radiotherapy patient plans using different treatment techniques and therapy machines were measured using the same measurement setup and irradiation intention...
  63. ncbi Lab-on-a-chip devices for global health: past studies and future opportunities
    Curtis D Chin
    Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
    Lab Chip 7:41-57. 2007
    ..We focus mainly on diagnostics, the nearest-term application in this field...
  64. pmc A wireless sensor network for vineyard monitoring that uses image processing
    Jaime Lloret
    Integrated Management Coastal Research Institute, Universidad Politecnica de Valencia, Grao de Gandia, Spain
    Sensors (Basel) 11:6165-96. 2011
  65. ncbi Systematic accuracy and precision analysis of video motion capturing systems--exemplified on the Vicon-460 system
    Markus Windolf
    AO Research Institute, Research Services Group, Clavadelerstrasse 8, CH 7270 Davos, Switzerland
    J Biomech 41:2776-80. 2008
    ..With careful configuration, optical motion capturing provides a powerful measuring opportunity for the majority of biomechanical applications...
  66. ncbi Tracheal intubation using the mobile C-MAC video laryngoscope or direct laryngoscopy for patients with a simulated difficult airway
    C Byhahn
    Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, J W Goethe University Hospital Frankfurt, Frankfurt, Germany
    Minerva Anestesiol 76:577-83. 2010
  67. ncbi A new ultrasound instrument for in vivo microimaging of mice
    F S Foster
    Dept of Medical Biophysics, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Ultrasound Med Biol 28:1165-72. 2002
    ..Noninvasive UBM assessment of development shows striking similarity to invasive atlases of mouse anatomy. The most detailed noninvasive in vivo images of mouse embryonic development achieved using any imaging method are presented...
  68. ncbi First clinical evaluation of the C-MAC D-Blade videolaryngoscope during routine and difficult intubation
    Erol Cavus
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig Holstein, Campus Kiel, Schwanenweg 21, D 24105 Kiel, Germany
    Anesth Analg 112:382-5. 2011
    ..In all 35 patients, with the D-Blade no direct view of the glottis was possible and subsequently a semiflexible tube guide was required...
  69. ncbi Optimizing compliant, model-based robotic assistance to promote neurorehabilitation
    Eric T Wolbrecht
    Mechanical Engineering Department, University of Idaho, Moscow, ID 83844, USA
    IEEE Trans Neural Syst Rehabil Eng 16:286-97. 2008
    ..The experiments also demonstrate how including the "assist-as-needed" modification in the controller increases participation from the motor system...
  70. ncbi Graphene-on-paper sound source devices
    He Tian
    Institute of Microelectronics, Tsinghua University, Beijing 100084, China
    ACS Nano 5:4878-85. 2011
    ..It could open wide applications in multimedia, consumer electronics, biological, medical, and many other areas...
  71. pmc Hepatic radiofrequency ablation using multiple probes: ex vivo and in vivo comparative studies of monopolar versus multipolar modes
    Jeong Min Lee
    Department of Radiology, and Institute of Radiation Medicine, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    Korean J Radiol 7:106-17. 2006
  72. ncbi High-resolution surface plasmon resonance sensors based on a dove prism
    Olivier R Bolduc
    Departement de Chimie, Universite de Montreal, C P 6128 Succ Centre Ville, Montreal, QC, Canada H3C 3J7
    Talanta 77:1680-7. 2009
    ..SPR using a dove prism configuration combines advantages of portable SPR instruments, SPR imagers and research-grade SPR instruments in a unique platform...
  73. ncbi Fabric-based active electrode design and fabrication for health monitoring clothing
    Carey R Merritt
    Department of Electrical and Computer Engineering, North Carolina State University, Raleigh, NC 27695, USA
    IEEE Trans Inf Technol Biomed 13:274-80. 2009
    ..The interposer-based active electrodes survived a five-cycle washing test while maintaining good signal integrity...
  74. ncbi Adaptive dynamic range optimization for cochlear implants: a preliminary study
    Chris J James
    Cooperative Research Centre for Cochlear Implant and Hearing Aid Innovation, The University of Melbourne, Australia
    Ear Hear 23:49S-58S. 2002
    ..ADRO is a preprocessing scheme that continuously adjusts the gain in each frequency band to optimize the signal in the output dynamic range...
  75. ncbi A method for internal fixation of unstable distal clavicle fractures: early observations using a new technique
    Michael Kalamaras
    Hand and Upper Limb Unit, Princess Alexandra Hospital, and Brisbane Hand and Upper Limb Clinic, Brisbane, Australia
    J Shoulder Elbow Surg 17:60-2. 2008
    ..None of the current fixation methods seem to be without problems. We present a new technique and early observations using a distal radius locking T-plate normally used for fixation of distal radius fractures...
  76. ncbi Wireless contact lens sensor for intraocular pressure monitoring: assessment on enucleated pig eyes
    Matteo Leonardi
    Swiss Federal Institute of Technology, Lausanne, Switzerland
    Acta Ophthalmol 87:433-7. 2009
    ..Assessment on enucleated pig eyes of a novel and minimally invasive method for the continuous monitoring of intraocular pressure (IOP), based on a novel wireless contact lens sensor (CLS)...
  77. ncbi Ultrasensitive photonic crystal fiber refractive index sensor
    Darran K C Wu
    Centre for Ultrahigh Bandwidth Devices for Optical Systems, School of Physics, University of Sydney, Sydney, New South Wales, Australia
    Opt Lett 34:322-4. 2009
    ..A detection limit of 4.6x10(-7) refractive index units has been derived from measurements with a sensitivity of 30,100 nm per refractive index unit, which is the highest for a fiber device to date...
  78. ncbi Noninvasive imaging of hemoglobin concentration and oxygenation in the rat brain using high-resolution photoacoustic tomography
    Xueding Wang
    Texas A and M University, Department of Biomedical Engineering, Optical Imaging Laboratory, 3120 TAMU, College Station, Texas 77843 3120, USA
    J Biomed Opt 11:024015. 2006
    ..This technique, with its prominent sensitivity to endogenous contrast, can potentially contribute to the understanding of the interrelationship between neural, hemodynamic, and metabolic activities in the brain...
  79. ncbi Portable exhaled nitric oxide measurement: Comparison with the "gold standard" technique
    Daniel Menzies
    Asthma and Allergy Research Group, Dundee, Scotland, UK
    Chest 131:410-4. 2007
    ..A portable nitric oxide analyzer (MINO; Aerocrine AB; Smidesvägen, Sweden) has been developed, but few data exist comparing this device with established, larger laboratory-based analyzers (NIOX; Aerocrine AB)...
  80. ncbi Agreement and repeatability of central thickness measurement in normal corneas using ultrasound pachymetry and the OCULUS Pentacam
    Clare O'Donnell
    Faculty of Life Sciences, The University of Manchester, UK
    Cornea 24:920-4. 2005
    ..To compare the accuracy and repeatability of the OCULUS Pentacam (a new Scheimpflug-based imaging system) with ultrasound pachymetry in the measurement of central corneal thickness (CCT)...
  81. ncbi Valve-based microfluidic compression platform: single axon injury and regrowth
    Suneil Hosmane
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Lab Chip 11:3888-95. 2011
    ..At severe levels of injury (> 95 kPa), virtually all axons were instantaneously transected and nearly half (~46%) of these axons were able to regrow within the imaging period in the absence of exogenous stimulating factors...
  82. ncbi Cochlear implant speech recognition with speech maskers
    Ginger S Stickney
    University of California, Department of Otolaryngology Head and Neck Surgery, Irvine, California 92697 1275, USA
    J Acoust Soc Am 116:1081-91. 2004
    ..This informational masking may originate from increased target-masker similarity when spectral resolution is reduced...
  83. ncbi Wearable medical systems for p-Health
    Xiao Fei Teng
    Department of Electronic Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    IEEE Rev Biomed Eng 1:62-74. 2008
  84. pmc Spatial light interference tomography (SLIT)
    Zhuo Wang
    Department of Electrical and Computer Engineering, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Opt Express 19:19907-18. 2011
    ..We illustrate the method with reconstructed tomographic refractive index distributions of microspheres, photonic crystals, and unstained living cells...
  85. pmc An inexpensive method of small paraffin tissue microarrays using mechanical pencil tips
    Abdelhadi M Shebl
    Pathology Department, Faculty of Medicine, Mansoura University, Egypt
    Diagn Pathol 6:117. 2011
    ..This study was carried out in order to produce tissue microarray blocks using mechanical pencil tips without high cost...
  86. pmc Real-time 4D signal processing and visualization using graphics processing unit on a regular nonlinear-k Fourier-domain OCT system
    Kang Zhang
    Department of Electrical and Computer Engineering, The Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218, USA
    Opt Express 18:11772-84. 2010
    ..This technique is highly cost-effective and can be easily integrated into most ultrahigh speed FD-OCT systems to overcome the 3D data processing and visualization bottlenecks...
  87. ncbi Hierarchical three-dimensional ZnCo₂O₄ nanowire arrays/carbon cloth anodes for a novel class of high-performance flexible lithium-ion batteries
    Bin Liu
    Wuhan National Laboratory for Optoelectronics and College of Optoelectronic Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China
    Nano Lett 12:3005-11. 2012
    ..Highly flexible full batteries were also fabricated, exhibiting high flexibility, excellent electrical stability, and superior electrochemical performances...
  88. pmc Implementation of a digital optical phase conjugation system and its application to study the robustness of turbidity suppression by phase conjugation
    Meng Cui
    Department of Electrical Engineering, California Institute of Technology, 1200 E California Blvd, MC 136 93, CA, 91125, USA
    Opt Express 18:3444-55. 2010
  89. ncbi An MR-compatible bicycle ergometer for in-magnet whole-body human exercise testing
    Jeroen A L Jeneson
    Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    Magn Reson Med 63:257-61. 2010
    ..The basic design of the ergometer is highly generic and adaptable for application on a wide selection of whole-body MR scanners...
  90. pmc Patient specific ankle-foot orthoses using rapid prototyping
    Constantinos Mavroidis
    Department of Mechanical and Industrial Engineering, Northeastern University, Boston, MA 02115, USA
    J Neuroeng Rehabil 8:1. 2011
    ..A computerized technique for fabricating patient-specific orthotic devices has the potential to provide excellent comfort and allow for changes in the standard design to meet the specific needs of each patient...
  91. pmc Intravascular laser speckle imaging catheter for the mechanical evaluation of the arterial wall
    Zeinab Hajjarian
    Massachusetts General Hospital, Wellman Center for Photomedicine, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Biomed Opt 16:026005. 2011
    ..Distinct differences in arterial time constants are identified at normal aortic and stented sites in vivo with intravascular LSI...
  92. ncbi Understanding speech in modulated interference: cochlear implant users and normal-hearing listeners
    Peggy B Nelson
    Department of Communication Disorders, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Acoust Soc Am 113:961-8. 2003
    ..The lack of release from masking occurs in implant listeners independent of their device characteristics, and may be attributable to the nature of implant processing strategies and/or the lack of spectral detail in processed stimuli...
  93. ncbi In vivo MR micro imaging with conventional radiofrequency coils cooled to 77 degrees K
    A C Wright
    Department of Radiology, Hosptial of the University of Pennsylvania, Philadelphia 19104, USA
    Magn Reson Med 43:163-9. 2000
    ..The performance of the coil is illustrated with images from the human finger and rabbit eye and potential applications are discussed...
  94. ncbi Long-term high-resolution imaging and culture of C. elegans in chip-gel hybrid microfluidic device for developmental studies
    Jan Krajniak
    School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA
    Lab Chip 10:1862-8. 2010
    ..We show here that this method facilitates time-lapse studies of single animals at high-resolution and lends itself to live imaging experiments on developmental processes and dynamic events...
  95. ncbi Surface acoustic wave actuated cell sorting (SAWACS)
    T Franke
    Department of Physics and School of Engineering and Applied Science, Harvard University, Cambridge, USA
    Lab Chip 10:789-94. 2010
    ..We have successfully directed HaCaT cells (human keratinocytes), fibroblasts from mice and MV3 melanoma cells. The low shear forces of this sorting method ensure that cells survive after sorting...
  96. pmc Adrenaline in the treatment of anaphylaxis: what is the evidence?
    Andrew P C McLean-Tooke
    Regional Department of Immunology and Allergy, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP
    BMJ 327:1332-5. 2003
  97. ncbi Injuries caused by Veress needle insertion for creation of pneumoperitoneum: a systematic literature review
    Joao Luiz Moreira Coutinho Azevedo
    Department of Surgery, Division of Operative Techniques and Experimental Surgery, Federal University of Sao Paulo, Sao Paulo, Brazil
    Surg Endosc 23:1428-32. 2009
    ..The aim of this study was to assess the prevalence, risks, and outcomes of injuries caused by the Veress needle described in the literature...
  98. ncbi Description and validation of the apnea risk evaluation system: a novel method to diagnose sleep apnea-hypopnea in the home
    Philip R Westbrook
    Advanced Brain Monitoring, Inc, 2850 Pio Pico Dr, Suite A, Carlsbad, CA 92008, USA
    Chest 128:2166-75. 2005
    ..To evaluate the accuracy and practicality of the Apnea Risk Evaluation System (ARES; Advanced Brain Monitoring; Carlsbad, CA), a limited-channel system for diagnosing sleep apnea/hypopnea in the home...
  99. ncbi Long-term outcome of endovascular reconstruction with the Pipeline embolization device in the management of unruptured dissecting aneurysms of the intracranial vertebral artery
    Tsz Wai Yeung
    Department of Radiology, Tuen Mun Hospital, Tuen Mun, China
    J Neurosurg 116:882-7. 2012
    ..The authors report their initial experience with respect to the potential utility and long-term clinical outcomes of using a flow-diverting device in the treatment of unruptured dissecting VA aneurysms...
  100. ncbi Diffuse optical measurement of blood flow in breast tumors
    Turgut Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Opt Lett 30:2915-7. 2005
    ..Increased blood flow was observed in tumor regions relative to healthy tissue, and control subjects did not exhibit significant blood flow heterogeneity. The measurements introduce a new optical contrast for diffuse optical mammography...
  101. ncbi Potential sources of intrinsic optical signals imaged in live brain slices
    R D Andrew
    Queen s University, Kingston, Ontario, K7L 3N6, Canada
    Methods 18:185-96, 179. 1999
    ..5) While hyperosmotic conditions reduce LT by causing cells to shrink, excitotoxic conditions reduce LT by causing dendritic beading. This conformational change increases light scattering even as the tissue continues to swell...

Research Grants72

    Christopher W Tyler; Fiscal Year: 2011
    ..of its most important shared research services, including computer communication and resources and electronic equipment design and maintenance, but extending more recently to multi-investigator support for the wealth of brain imaging ..
  2. Multidisciplinary Team-Based Design Education to Create Biomedical Engineering In
    JAY RICHARD GOLDBERG; Fiscal Year: 2013
  3. Resistance to Aortic Endograft Migration: Comparative Effectiveness of FDA Approv
    Christopher K Zarins; Fiscal Year: 2010
    ..Furthermore, there are currently no studies that compare the performance of the different devices with regards to their long term positional stability (migration). ..
  4. Enhancing Biomedical Engineering Senior Design at Northwestern University
    ..The enhancements to the program proposed here will expand these programs and extend the ideas to address analogous problems in health care in Chicago and the surrounding communities. ..
    JEFFREY WOLCHOK; Fiscal Year: 2013
  6. Multi-disciplinary, Undergraduate Design Teams to Meet Healthcare Needs
    Dustin J Tyler; Fiscal Year: 2013
  7. BIGDATA: Modeling Simulation and Visulization for Medical Device Design
    Daniel F Keefe; Fiscal Year: 2013
  8. Diabetes Initiative for Applied Biomedical Engineering
    Brian Davis; Fiscal Year: 2007
    ..The proposed curriculum will become an educational model for ensuring that graduates master the requisite skills to contribute to teams focused on conquering the devastating consequences of diabetes. [unreadable] [unreadable]..
  9. Photoablation System to Make Microfluidic Structures
    KANTI JAIN; Fiscal Year: 2003
    ..In Phase I of this proposal, we will develop the equipment design, specifically focusing on the selection and incorporation of the spatial light modulator into the ..
    PHILLIP DELEEL; Fiscal Year: 1999
    ..The proposed equipment design will allow CPH?s Information Technology staff to administer and manage Internet accessibility to its own main ..
  11. Force Field Development for Protein Absorption Modeling
    Robert Latour; Fiscal Year: 2009
  12. Novel Acoustic Method: Rapid, High-Yield Islet Isolation
    BRYAN BOHANAN; Fiscal Year: 2001
    ..52 to 1.04 million patients with 39,900 to 79,800 patients added annually. Therefore, the conservative market base for the proposed system is $65 to $130 million with annual additions of between $5.0 and $10.0 million. ..
    Richard Kelly; Fiscal Year: 1990
    Christy Holland; Fiscal Year: 1999
    ..acoustic output over previously allowable levels, provided that an output display is incorporated into the equipment design. Based on these changes in acoustic output regulation and recent evidence of potential biological effects of ..
  15. Multivalency: Mechanisms and Applications
    George M Whitesides; Fiscal Year: 2010
  16. Tools To Study Cell Motility and Ion Channels
    George Whitesides; Fiscal Year: 2006
    ..The work spans biology, microfabrication, and biophysics, and an important product of the research will be students broadly trained in biological and physical sciences. ..
  17. Capillary Electrophoresis and Protein Biophysics
    George M Whitesides; Fiscal Year: 2010
  18. Back Disorders in Union Carpenters
    Hester Lipscomb; Fiscal Year: 2006
    ..The project addresses a number of areas of expressed interest to NIOSH including construction workers, back disorders, surveillance methods and health services research. [unreadable] [unreadable]..
  19. Effectiveness of patient lift equipment
    Hester Lipscomb; Fiscal Year: 2008
    ..The proposed work addresses several NIOSH priority areas including health care workers, back injuries, and intervention effectiveness research. ..
  20. Robotic Mastoidectomy
    Robert Labadie; Fiscal Year: 2008
    ..It is hypothesized that this strategy will be more efficient than either the human or robotic interventions examined in Specific Aim 2. [unreadable] [unreadable] [unreadable]..
    Hester Lipscomb; Fiscal Year: 2004
    ..Education will also be targeted to medical providers in this geographic area on work exposures and conditions, exposure response, prevention, basic epidemiology, and ergonomics. ..
  22. Image-Guided Otologic Surgery
    Robert Labadie; Fiscal Year: 2004
    ..It is anticipated that this system will make ear surgery safer and more efficient. ..
  23. Development of Guidelines and Assessment Tools for Truck Ingress/Egress
    Matthew Reed; Fiscal Year: 2009
    ..The guidelines and assessment methods will be disseminated through publications, standards organizations, and a dedicated website. ..
  24. Developing computerized tools for cryosurgery planning
    Yoed Rabin; Fiscal Year: 2007
    ..Such visualization capabilities will provide surgeons with insights into the physics of cryosurgery that are difficult to obtain from physical experiments or surgical practice. [unreadable] [unreadable]..
  25. Lipoprotein Utilization and Oxidation in CHF
    Ulrich P Jorde; Fiscal Year: 2010
    ..If our hypotheses can be proven, they may lead to developments of new therapies to improve exercise capacity and longevity in patients afflicted with CHF. ..
    Norma Metheny; Fiscal Year: 2007
    ..Delivery, receipt and enactment of the ARRP will be evaluated by quantitative and qualitative methods. [unreadable] [unreadable] [unreadable]..
  27. MSM-Multi-scale Analysis of Cellular Force Transmission and Biochemical Activatio
    Roger Kamm; Fiscal Year: 2007
    ..4. Conduct experiments in reconstituted actin networks to provide a pheonological basis for evaluation and evalidation of the computational models. ..
  28. Long-term prediction of prostate cancer death from kallikreins measured in blood
    Hans Lilja; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  29. Early experience and low 5-HT markers in alcohol abuse
    Mark Laudenslager; Fiscal Year: 2009
    ..Finally, involvement of the HPA axis in these relationships will be investigated as an exploratory goal. ..
    Mark Laudenslager; Fiscal Year: 2003
    ..The present application seeks to identify developmental factors affecting the HPA axis and the balance of CORT and DHEA with consequences for individual differences in rates of progression in immunodeficiency disease. ..
  31. Development of a 'Nurse-Friendly' Bedside Test for Aspiration
    Norma A Metheny; Fiscal Year: 2010
  32. Microdevice for Direct DNA Purification
    James Landers; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  33. Veterinary Comparative Respiratory Society 2008 Symposium
    Michael Davis; Fiscal Year: 2008
    ..This symposium will review the current knowledge and practical challenges of these models in order to make them more accessible to the biomedical research community. [unreadable] [unreadable] [unreadable]..
  34. ACHA Research Symposium Adult Congenital Heart Disease
    Elyse Foster; Fiscal Year: 2006
    ..Outstanding junior investigators will be given the opportunity to present their research. The Symposium will conclude with each subsection recommending specific future research endeavors and outlining necessary future actions. ..
  35. Non-contact microchip PCR based on infrared Heating
    James Landers; Fiscal Year: 2005
    ..k.a., a true lab-on-a-chip). ..
  36. Micro-Solid Phase Extraction of DNA on Microchips
    James Landers; Fiscal Year: 2005
    ..This will allow optimal use of the DNA extracted from the sample in the PCR amplification. ..
    Michael Davis; Fiscal Year: 2004
    ..The investigators will use these same measurements to determine the changes in pulmonary mechanics and airway inflammation in dogs that perform repeated exercise in frigid environments. ..
  38. Thermo mechanical stress in cryopreserved blood vessels
    Yoed Rabin; Fiscal Year: 2006
    ..Although the experimental work in this study is targeted to blood vessels, the results of this study could be expanded and become useful for a wide variety of cryopreserved natural tissues and engineered constructs. ..
  39. Erythema and deep tissue injury detector
    Stephen Sprigle; Fiscal Year: 2004
    ..A significant focus is on enhanced detection in people with darkly pigmented since, in whom visual inspection is problematic. ..
    Roger Kamm; Fiscal Year: 2001
    ..Specific Aim 3. To test the hypothesis that sites of inflammation/degradation correlate with regions within the tissue that experience high mechanical strain. ..
  41. NCRR Training Grant for Veterinary Students in Research
    Michael Davis; Fiscal Year: 2006
    ..Over a three-year period this program will contribute nine comparative medical scientists with veterinary medical degrees who are well trained in animal-oriented, hypothesis-based research. [unreadable] [unreadable]..
    Akif Undar; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  43. Development of Networked Implantable Neuroprostheses
    P Peckham; Fiscal Year: 2002
    ..abstract_text> ..
  44. Restoration of hand-arm function with neuroprosthesis
    P Peckham; Fiscal Year: 2005
    ..Abstract Not Provided ..
  45. Modeling HIV Diffusion through Drug Using Networks
    William Zule; Fiscal Year: 2007
    ..abstract_text> ..
  46. Bioassay with magnetic particles in flow
    MICHELLE ESPY; Fiscal Year: 2005
    ..Combining SQUIDs for target identification with laser diagnostics to assess binding provides an efficient, high throughput multiplexed bioassay method based on traditional flow cytometry. ..
  47. Biomimetic Nanofibrillar Scaffolds For Cartilage Tissue Engineering
    Anu Subramanian; Fiscal Year: 2008
    ..The engineering methodology developed in this proposal may have broader impacts on the manufacturing of other surfaces for tissue engineering. [unreadable] [unreadable] [unreadable]..
    Akif Undar; Fiscal Year: 2008
    ..This will be the only national/international conference to focus solely on pediatric cardiac patients. (End of Abstract) [unreadable] [unreadable] [unreadable]..
  49. Mitral Annular Remodeling for MR Therapy
    Kiyotaka Fukamachi; Fiscal Year: 2005
    ..Therefore, this proposed research program is an important first step in this novel procedure's development as one potential therapeutic option for high-risk CHF patients with functional MR. ..
  50. Cartilage Integration: in Vitro to In Vivo Translation
    Robert Sah; Fiscal Year: 2006
    ..abstract_text> ..
  51. ErgoChair Smart Manual Wheelchair
    W Richter; Fiscal Year: 2008
    ..This project will develop innovative technology that will dramatically improve the ergonomics of wheelchair transfers and lifting tasks. [unreadable] [unreadable]..
  52. Cognitive Orthosis with Interactive Task and Planning
    Edmund Lopresti; Fiscal Year: 2004
    ..e., astronauts). Evaluation of the Solo system will be conducted through focus groups and usability tests with clinicians, and clinical trials with individuals who have cognitive impairments. ..
  53. A Microfluidic Chemotaxis High Throughput System
    Ivar Meyvantsson; Fiscal Year: 2007
    ..To enable the discovery of drugs to block this process, we are developing plastic devices for high throughput cell migration assays in defined chemical gradients. [unreadable] [unreadable] [unreadable]..
  54. Companion Microphones: Increased SNR for 3+ talkers
    MEAD KILLION; Fiscal Year: 2003
    ..In addition, a subjective value rating will provide a practical check on the utility of these developments. ..
  55. Longitudinal follow-up of hearing in construction workers
    Noah Seixas; Fiscal Year: 2009
    ..abstract_text> ..
  56. Rapid assessment of vascular grafts patency
    Hansen Mansy; Fiscal Year: 2008
    ..The potential market for our instrument is large given the number of individuals with either bypass grafts, or hemodialysis grafts or fistulas. [unreadable] [unreadable] [unreadable]..
  57. Thick scintillation detector with continuous positioning & DOI capability for PET
    Suleman Surti; Fiscal Year: 2008
    ..Hence, thick continuous detectors have the potential to significantly impact the clinical imaging situation and the resultant patient treatment. [unreadable] [unreadable] [unreadable]..
  58. In vivo Thermoacoustic Imaging of HER2 Status
    Robert Kruger; Fiscal Year: 2008
    ..3. Determine the minimum detectable concentration of IRIS Green One dye that can be detected within a 1.2-mm diameter tube in a breast-tissue mimicking phantom. ..
    Brett Spear; Fiscal Year: 2001
    ..In addition, the information derived from these studies may improve strategies to express foreign genes within the liver, a goal of many gene therapy trials. ..
  60. Afri 1: Gene Cloning and its Role in Liver Regulation
    Brett Spear; Fiscal Year: 2006
    ..We can then understand how Afr1 regulates AFP and we are likely to learn more about the transcription/post/transcriptional connections as well as how this may be developmentally regulated to control gene expression. ..
  61. Dectection of occult mediastinal lymph node mestastases
    Michael Wallace; Fiscal Year: 2007
    ..In the R33 component of the grant application these criteria will be prospectively evaluated and correlated with clinical outcome in a second, larger cohort of patients. ..
    Thomas Lewellen; Fiscal Year: 2002
    ..g. mouse, rat, rabbit, dog, and primate). The final detector module designs will be fully documented (including ASIC fabrication files) to allow duplication at other laboratories. ..
    Thomas Lewellen; Fiscal Year: 2005
    ..Animal support and radiopharmaceuticals will be provided by existing cost centers within the University of Washington Department of Radiology. ..
  64. LifeSkills Video Training in Patients with Implanted ICD
    Joseph Rogers; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  65. Feasibility of CT in high risk breast cancer patients
    John Boone; Fiscal Year: 2003
    ..The results of this investigation should provide a clear understanding of the potential of breast CT as a tool to reduce breast cancer mortality in the population of women with dire risk of breast cancer. ..
  66. Mesoporus Diamondlike Carbon Medical Device Membrane
    Roger Narayan; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  67. Hybrid Nuclear/X-ray Projection System for Mouse Imaging
    John Boone; Fiscal Year: 2005
    ..abstract_text> ..
  68. Breast CT scanner for earlier cancer detection
    John Boone; Fiscal Year: 2002
    ..that particularly warrant screening using breast CT. The Phase II trial will shed more light on this issue. ..
  69. Pulsed Electron Avalanche Knife: Intraocular Microsurg.
    Daniel Palanker; Fiscal Year: 2006
    ..The low cost and small size of this system combined with high precision, reliability and versatility should allow for a widespread acceptance into operating practice. ..
  70. Neutron Microscope for In-Vivo Imaging
    JAY CREMER; Fiscal Year: 2005
    ..abstract_text> ..
  71. Randomized Trial of EUS Neurolysis in Pancreas Cancer
    Michael Wallace; Fiscal Year: 2006
    ..The primary outcome will be a reduction in pain at 1 month. Secondary outcomes will include the durability of pain control, quality of life, narcotic use and narcotic side effects. [unreadable] [unreadable]..