regression analysis


Summary: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.

Top Publications

  1. ncbi A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group
    A S Levey
    New England Medical Center, Boston, MA 02111, USA
    Ann Intern Med 130:461-70. 1999
  2. ncbi Permutation tests for joinpoint regression with applications to cancer rates
    H J Kim
    Syracuse University, Department of Mathematics, 215 Carnegie Building, Syracuse University, Syracuse, NY 13244 1150, USA
    Stat Med 19:335-51. 2000
  3. ncbi Segmented regression analysis of interrupted time series studies in medication use research
    A K Wagner
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    J Clin Pharm Ther 27:299-309. 2002
  4. doi A working guide to boosted regression trees
    J Elith
    School of Botany, The University of Melbourne, Parkville, Victoria, Australia
    J Anim Ecol 77:802-13. 2008
  5. pmc Identification of genes required for cellulose synthesis by regression analysis of public microarray data sets
    Staffan Persson
    Department of Plant Biology, Carnegie Institution, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 102:8633-8. 2005
  6. ncbi Temperature and mortality in 11 cities of the eastern United States
    Frank C Curriero
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Epidemiol 155:80-7. 2002
  7. pmc Urinary creatinine concentrations in the U.S. population: implications for urinary biologic monitoring measurements
    Dana B Barr
    National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Environ Health Perspect 113:192-200. 2005
  8. pmc Predicting quantitative traits with regression models for dense molecular markers and pedigree
    Gustavo de Los Campos
    Department of Animal Sciences, University of Wisconsin, Madison, Wisconsin 53706, USA
    Genetics 182:375-85. 2009
  9. pmc Epidemiologic evaluation of measurement data in the presence of detection limits
    Jay H Lubin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Environ Health Perspect 112:1691-6. 2004
  10. pmc Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: a global collaborative study and meta-regression analysis
    Ravindra K Gupta
    Department of Infection, University College London, London, UK
    Lancet 380:1250-8. 2012

Detail Information

Publications319 found, 100 shown here

  1. ncbi A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group
    A S Levey
    New England Medical Center, Boston, MA 02111, USA
    Ann Intern Med 130:461-70. 1999
    ..Serum creatinine concentration is widely used as an index of renal function, but this concentration is affected by factors other than glomerular filtration rate (GFR)...
  2. ncbi Permutation tests for joinpoint regression with applications to cancer rates
    H J Kim
    Syracuse University, Department of Mathematics, 215 Carnegie Building, Syracuse University, Syracuse, NY 13244 1150, USA
    Stat Med 19:335-51. 2000
    ..The performance of these tests are studied via simulations and the tests are applied to U.S. prostate cancer incidence and mortality rates...
  3. ncbi Segmented regression analysis of interrupted time series studies in medication use research
    A K Wagner
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    J Clin Pharm Ther 27:299-309. 2002
    ..Segmented regression analysis is a powerful statistical method for estimating intervention effects in interrupted time series studies...
  4. doi A working guide to boosted regression trees
    J Elith
    School of Botany, The University of Melbourne, Parkville, Victoria, Australia
    J Anim Ecol 77:802-13. 2008
    ..We use a data set of over 13 000 sites to illustrate effects of several settings, and then fit and interpret a model using a subset of the data. We provide code and a tutorial to enable the wider use of BRT by ecologists...
  5. pmc Identification of genes required for cellulose synthesis by regression analysis of public microarray data sets
    Staffan Persson
    Department of Plant Biology, Carnegie Institution, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 102:8633-8. 2005
    ..Thus, the general approach developed here is useful for identification of elements of multicomponent processes...
  6. ncbi Temperature and mortality in 11 cities of the eastern United States
    Frank C Curriero
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Epidemiol 155:80-7. 2002
    ..for 11 large eastern US cities in 1973-1994 by estimating the relative risks of mortality using log-linear regression analysis for time-series data and by exploring city characteristics associated with variations in this temperature-..
  7. pmc Urinary creatinine concentrations in the U.S. population: implications for urinary biologic monitoring measurements
    Dana B Barr
    National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Environ Health Perspect 113:192-200. 2005
    ..g., children with children, adults with adults). For multiple regression analysis of population groups, we recommend that the analyte concentration (unadjusted for creatinine) should be ..
  8. pmc Predicting quantitative traits with regression models for dense molecular markers and pedigree
    Gustavo de Los Campos
    Department of Animal Sciences, University of Wisconsin, Madison, Wisconsin 53706, USA
    Genetics 182:375-85. 2009
    ..Results indicate that inclusion of markers in the regression further improved the predictive ability of models. An R program that implements the proposed model is freely available...
  9. pmc Epidemiologic evaluation of measurement data in the presence of detection limits
    Jay H Lubin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Environ Health Perspect 112:1691-6. 2004
    ..We illustrate various approaches using measurements of pesticide residues in carpet dust in control subjects from a case-control study of non-Hodgkin lymphoma...
  10. pmc Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: a global collaborative study and meta-regression analysis
    Ravindra K Gupta
    Department of Infection, University College London, London, UK
    Lancet 380:1250-8. 2012
    ..We aimed to estimate changes in the prevalence of HIV-1 drug resistance in treatment-naive individuals with HIV since initiation of rollout in resource-limited settings...
  11. ncbi Swedish population health-related quality of life results using the EQ-5D
    K Burstrom
    Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden
    Qual Life Res 10:621-35. 2001
    ..0001). In conclusion, our results show that the HRQoL varies greatly between socio-economic and disease groups. Furthermore, after controlling for age, sex and disease, HRQoL is lower in manual than in non-manual groups...
  12. ncbi What you see may not be what you get: a brief, nontechnical introduction to overfitting in regression-type models
    Michael A Babyak
    Duke University Medical Center, Durham, NC 27710, USA
    Psychosom Med 66:411-21. 2004
    ..Techniques that account and correct for complexity, including shrinkage and penalization, also are introduced...
  13. ncbi Waist circumference percentiles in nationally representative samples of African-American, European-American, and Mexican-American children and adolescents
    Jose R Fernandez
    Section on Statistical Genetics, Department of Biostatistics, Clinical Nutrition Research Center, University of Alabama at Birmingham, 35294 3360, USA
    J Pediatr 145:439-44. 2004
    ..To describe and provide estimates of the distribution of waist circumference (WC) according to percentiles in African-, European-, and Mexican-American children, and to test for group differences at different percentiles...
  14. ncbi Cognitive and behavioral outcomes of school-aged children who were born preterm: a meta-analysis
    Adnan T Bhutta
    Department of Pediatrics, Arkansas University for Medical Sciences, Little Rock, USA
    JAMA 288:728-37. 2002
    ..The cognitive and behavioral outcomes of school-aged children who were born preterm have been reported extensively. Many of these studies have methodological flaws that preclude an accurate estimate of the long-term outcomes of prematurity...
  15. ncbi Socioeconomic inequalities in depression: a meta-analysis
    V Lorant
    Health Systems Research, School of Public Health, Faculty of Medicine, Universite Catholique de Louvain, Brussels, Belgium
    Am J Epidemiol 157:98-112. 2003
    ..Nonetheless, the authors found compelling evidence for socioeconomic inequality in depression. Strategies for tackling inequality in depression are needed, especially in relation to the course of the disorder...
  16. ncbi Akaike's information criterion in generalized estimating equations
    W Pan
    Division of Biostatistics, University of Minnesota, Minneapolis 55455, USA
    Biometrics 57:120-5. 2001
    Correlated response data are common in biomedical studies. Regression analysis based on the generalized estimating equations (GEE) is an increasingly important method for such data...
  17. pmc Exposure measurement error in time-series studies of air pollution: concepts and consequences
    S L Zeger
    Johns Hopkins University, School of Public Health, Baltimore, Maryland, USA
    Environ Health Perspect 108:419-26. 2000
    ..Finally, we summarize open questions regarding measurement error and suggest the kind of additional data necessary to address them...
  18. doi International study of temperature, heat and urban mortality: the 'ISOTHURM' project
    Anthony J McMichael
    National Centre for Epidemiology and Population Health, The Australian National University College of Medicine and Health Sciences, Canberra, Australia
    Int J Epidemiol 37:1121-31. 2008
    ..This study describes heat- and cold-related mortality in 12 urban populations in low- and middle-income countries, thereby extending knowledge of how diverse populations, in non-OECD countries, respond to temperature extremes...
  19. doi Screening and prostate-cancer mortality in a randomized European study
    Fritz H Schroder
    Department of Urology, Erasmus Medical Center, Rotterdam, The Netherlands
    N Engl J Med 360:1320-8. 2009
    ..The European Randomized Study of Screening for Prostate Cancer was initiated in the early 1990s to evaluate the effect of screening with prostate-specific-antigen (PSA) testing on death rates from prostate cancer...
  20. pmc Sparse inverse covariance estimation with the graphical lasso
    Jerome Friedman
    Department of Statistics, Stanford University, CA 94305, USA
    Biostatistics 9:432-41. 2008
    ..It also provides a conceptual link between the exact problem and the approximation suggested by Meinshausen and Bühlmann (2006). We illustrate the method on some cell-signaling data from proteomics...
  21. doi Efficacy of methylphenidate for adults with attention-deficit hyperactivity disorder: a meta-regression analysis
    Xavier Castells
    Psychiatry Department, Hospital Universitari Vall dHebron, Barcelona, Spain
    CNS Drugs 25:157-69. 2011
    ..The reasons for this variability have not been comprehensively investigated...
  22. ncbi Use of the Internet and e-mail for health care information: results from a national survey
    Laurence Baker
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, Calif 94305 5405, USA
    JAMA 289:2400-6. 2003
    ..Available estimates of use and impact vary widely. Without accurate estimates of use and effects, it is difficult to focus policy discussions or design appropriate policy activities...
  23. ncbi Longitudinal magnetic resonance imaging studies of older adults: a shrinking brain
    Susan M Resnick
    Laboratory of Personality and Cognition, National Institute on Aging, Baltimore, Maryland 21224 6825, USA
    J Neurosci 23:3295-301. 2003
  24. ncbi Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain
    Klaus Schmierer
    Department of Neuroinflammation, MS NMR Research Unit, University College London, United Kingdom
    Ann Neurol 56:407-15. 2004
    ..MRI and pathological data were in most cases coregistered using stereotactic navigation. Using multiple regression analysis, we detected significant correlations between myelin content (Tr(myelin)) and MTR (r = -0.84, p < 0...
  25. doi A relationship matrix including full pedigree and genomic information
    A Legarra
    INRA, UR631 SAGA, BP 52627, 32326 Castanet Tolosan, France
    J Dairy Sci 92:4656-63. 2009
    ..Numerical examples and alternative expressions are discussed. Matrix H is suitable for iteration on data algorithms that multiply a vector times a matrix, such as preconditioned conjugated gradients...
  26. ncbi Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease
    P M Ridker
    Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
    JAMA 285:2481-5. 2001
    ..Several novel risk factors for atherosclerosis have recently been proposed, but few comparative data exist to guide clinical use of these emerging biomarkers...
  27. doi Regression analysis of spatial data
    Colin M Beale
    The Macaulay Institute, Craigiebuckler, Aberdeen, AB15 8QH, UK
    Ecol Lett 13:246-64. 2010
  28. doi Strategic role of frontal white matter tracts in vascular cognitive impairment: a voxel-based lesion-symptom mapping study in CADASIL
    Marco Duering
    Institute for Stroke and Dementia Research, Ludwig Maximilians University, Munich, Germany
    Brain 134:2366-75. 2011
    ..Together these findings provide strong support for a central role of frontal-subcortical circuits in cerebral small vessel disease and vascular cognitive impairment...
  29. pmc A brief conceptual tutorial of multilevel analysis in social epidemiology: using measures of clustering in multilevel logistic regression to investigate contextual phenomena
    Juan Merlo
    Department of Clinical Sciences Community Medicine, Malmo University Hospital, Faculty of Medicine, Lund University, S 205 02 Malmo, Sweden
    J Epidemiol Community Health 60:290-7. 2006
    ..The aim of this study was to present measures of variation appropriate for the logistic case in a didactic rather than a mathematical way...
  30. ncbi Predicting the outcome of total knee arthroplasty
    Elizabeth A Lingard
    Brigham and Women s Hospital, 75 FrancisStreet, Boston, MA 02115, USA
    J Bone Joint Surg Am 86:2179-86. 2004
    ..This paper examines the preoperative predictors of pain and functional outcome at one and two years following total knee arthroplasty...
  31. ncbi Controlling the risk of spurious findings from meta-regression
    Julian P T Higgins
    MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, U K
    Stat Med 23:1663-82. 2004
    ..The permutation test appropriately tempers the statistical significance of meta-regression findings. We recommend its use before a statistically significant relationship is claimed from a standard meta-regression analysis.
  32. ncbi Household risk factors for malaria among children in the Ethiopian highlands
    T A Ghebreyesus
    Tigray Health Bureau, Mekelle, Ethiopia
    Trans R Soc Trop Med Hyg 94:17-21. 2000
  33. pmc Estimation of pairwise relatedness with molecular markers
    M Lynch
    Department of Biology, University of Oregon, Eugene, Oregon 97403
    Genetics 152:1753-66. 1999
    ..Two examples are given in which the new estimators are applied to natural populations, one that reveals isolation-by-distance in an annual plant and the other that suggests a genetic basis for a coat color polymorphism in bears...
  34. doi Inequalities in healthy life years in the 25 countries of the European Union in 2005: a cross-national meta-regression analysis
    Carol Jagger
    Department of Health Sciences, University of Leicester, Leicester, UK
    Lancet 372:2124-31. 2008
    ..We investigated inequalities in life expectancies and healthy life years (HLYs) at 50 years of age for the 25 countries in the EU in 2005 and the potential for increasing the proportion of older people in the labour force...
  35. ncbi Body mass index and waist circumference independently contribute to the prediction of nonabdominal, abdominal subcutaneous, and visceral fat
    Ian Janssen
    School of Physical and Health Education, Queen s University, Kingston, Ontario, Canada
    Am J Clin Nutr 75:683-8. 2002
  36. ncbi Prognostic modelling with logistic regression analysis: a comparison of selection and estimation methods in small data sets
    E W Steyerberg
    Center for Clinical Decision Sciences, Department of Public Health, Erasmus University, Rotterdam, The Netherlands
    Stat Med 19:1059-79. 2000
    Logistic regression analysis may well be used to develop a prognostic model for a dichotomous outcome...
  37. doi Global vitamin D levels in relation to age, gender, skin pigmentation and latitude: an ecologic meta-regression analysis
    T Hagenau
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    Osteoporos Int 20:133-40. 2009
    ..Serum 25(OH)D levels on average were 54 nmol/l, were higher in women than men, and higher in Caucasians than in non-Caucasians. There was no trend in serum 25(OH)D level with latitude. Vitamin D deficiency was widespread...
  38. ncbi A step-by-step guide to non-linear regression analysis of experimental data using a Microsoft Excel spreadsheet
    A M Brown
    Department of Neurology, Box 356465, University of Washington School of Medicine, Seattle, WA 98195 6465, USA
    Comput Methods Programs Biomed 65:191-200. 2001
    ..of this present study was to introduce a simple, easily understood method for carrying out non-linear regression analysis based on user input functions...
  39. ncbi Application of land use regression to estimate long-term concentrations of traffic-related nitrogen oxides and fine particulate matter
    Sarah B Henderson
    School of Occupational and Environmental Hygiene, The University of British Columbia, Vancouver, British Columbia, Canada
    Environ Sci Technol 41:2422-8. 2007
    ..62 and were similar across traffic metrics. Resulting maps show the distribution of NO to be more heterogeneous than that of NO2, supporting the usefulness of this approach for assessing spatial patterns of traffic-related pollution...
  40. pmc Cadmium exposure in pregnancy and lactation in relation to iron status
    Agneta Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Am J Public Health 92:284-7. 2002
    ..The purpose of this study was to determine the impact of iron status on cadmium dose among pregnant women...
  41. ncbi Why do we still use stepwise modelling in ecology and behaviour?
    Mark J Whittingham
    Division of Biology, School of Biology and Psychology, University of Newcastle, Newcastle upon Tyne, UK
    J Anim Ecol 75:1182-9. 2006
    ..In particular, the IT approach identifies large numbers of competing models that could describe the data equally well, showing that no one model should be relied upon for inference...
  42. ncbi Depression, chronic diseases, and decrements in health: results from the World Health Surveys
    Saba Moussavi
    Department of Measurement and Health Information Systems, World Health Organization, Geneva, Switzerland
    Lancet 370:851-8. 2007
    ..Depression is often comorbid with other chronic diseases and can worsen their associated health outcomes. Few studies have explored the effect of depression, alone or as a comorbidity, on overall health status...
  43. pmc Social capital and self-rated health: a contextual analysis
    I Kawachi
    Department of Health and Social Behavior, Harvard School of Public Health, Boston, Mass 02115, USA
    Am J Public Health 89:1187-93. 1999
    ..This article reports a contextual analysis of social capital and individual self-rated health, with adjustment for individual household income, health behaviors, and other covariates...
  44. pmc Renal function equations before and after living kidney donation: a within-individual comparison of performance at different levels of renal function
    Hilde Tent
    Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, Groningen, Netherlands
    Clin J Am Soc Nephrol 5:1960-8. 2010
    ..Whether this is due to the level of GFR as such or to differences in individual characteristics between healthy individuals and patient with chronic kidney disease (CKD) is unknown...
  45. pmc Case-mix and variation in specialist referrals in general practice
    Caoimhe O Sullivan
    University College London Hospital NHS Trust
    Br J Gen Pract 55:529-33. 2005
    ..The potential of a comprehensive measure of patient morbidity to explain variation in referrals to secondary care has not previously been examined in the UK...
  46. pmc Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, ON, Canada
    BMJ 338:b92. 2009
  47. pmc Cross-national comparisons of time trends in overweight inequality by socioeconomic status among women using repeated cross-sectional surveys from 37 developing countries, 1989-2007
    Jessica C Jones-Smith
    Department of Nutrition and Carolina Population Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27516 3997, USA
    Am J Epidemiol 173:667-75. 2011
    ..Among countries with a higher gross domestic product, lower income inequality was associated with faster overweight growth among the poor...
  48. doi Race and gender associations between obesity and nine health-related quality-of-life measures
    Tanya G K Bentley
    Partnership for Health Analytic Research, LLC, 280 South Beverly Drive 404, Beverly Hills, CA 90212, USA
    Qual Life Res 20:665-74. 2011
    ..To assess how health-related quality of life (HRQoL) varies by body mass index (BMI) category among gender and racial subgroups using nine HRQoL measures...
  49. ncbi Biodiversity and ecosystem multifunctionality
    Andy Hector
    Institute of Environmental Sciences, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Nature 448:188-90. 2007
    ..We conclude that because different species often influence different functions, studies focusing on individual processes in isolation will underestimate levels of biodiversity required to maintain multifunctional ecosystems...
  50. pmc The effect of weather on respiratory and cardiovascular deaths in 12 U.S. cities
    Alfesio L F Braga
    Environmental Epidemiology Program, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 110:859-63. 2002
    ..We saw no clear pattern for the effect of humidity. In hierarchical models, greater variance of summer and winter temperature was associated with larger effects for hot and cold days, respectively, on respiratory deaths...
  51. pmc Tracking of blood pressure from childhood to adulthood: a systematic review and meta-regression analysis
    Xiaoli Chen
    Center for Human Nutrition, Department of International Health, Bloomberg School of Public Health Johns Hopkins University, 615 N Wolfe St, Baltimore, MD 21205, USA
    Circulation 117:3171-80. 2008
    ..A large number of studies have examined the tracking of blood pressure (BP) from childhood to adulthood, but the reported findings are inconsistent and few systematic analyses have been conducted...
  52. ncbi Outcomes in young adulthood for very-low-birth-weight infants
    Maureen Hack
    Department of Pediatrics, Case Western Reserve University, Cleveland, USA
    N Engl J Med 346:149-57. 2002
    ..Very-low-birth-weight infants (those weighing less than 1500 g) born during the initial years of neonatal intensive care have now reached young adulthood...
  53. ncbi Relationship of subjective and objective social status with psychological and physiological functioning: preliminary data in healthy white women
    N E Adler
    Health Psychology Program, University of California, San Francisco 94143 0844, USA
    Health Psychol 19:586-92. 2000
    ..Results suggest that, in this sample with a moderately restricted range on SES and health, psychological perceptions of social status may be contributing to the SES-health gradient...
  54. doi A review of studies mapping (or cross walking) non-preference based measures of health to generic preference-based measures
    John E Brazier
    Health Economics and Decision Science, University of Sheffield, Regent Court, 30 Regent Street, Sheffield, S1 4DA, UK
    Eur J Health Econ 11:215-25. 2010
    ..Most testing in the literature occurs at the individual level yet the main purpose of these functions is to predict mean values for subgroups of patients, hence more testing is required...
  55. ncbi Individual patient- versus group-level data meta-regressions for the investigation of treatment effect modifiers: ecological bias rears its ugly head
    Jesse A Berlin
    University of Pennsylvania School of Medicine, Department of Biostatistics and Epidemiology and Center for Clinical Epidemiology and Biostatistics, Philadelphia, PA 19104 6021, USA
    Stat Med 21:371-87. 2002
    ..We recommend using individual patient data, when feasible, to study patient characteristics, in order to avoid the potential for ecological bias introduced by group-level analyses...
  56. ncbi Penalized Cox regression analysis in the high-dimensional and low-sample size settings, with applications to microarray gene expression data
    Jiang Gui
    Department of Statistics, University of California Davis, CA 95616, USA
    Bioinformatics 21:3001-8. 2005
    ..It would be desirable to have models with good prediction accuracy and parsimony property...
  57. ncbi A comparison of summary patient-level covariates in meta-regression with individual patient data meta-analysis
    P C Lambert
    Department of Epidemiology and Public Health, University of Leicester, 22 28 Princess Road West, LE1 6TP, Leicester, UK
    J Clin Epidemiol 55:86-94. 2002
    ..To compare meta-analysis of summary study level data with the equivalent individual patient data (IPD) analysis when interest lies in identification of binary patient characteristics related to treatment efficacy...
  58. ncbi Relations of moderate and vigorous physical activity to fitness and fatness in adolescents
    Bernard Gutin
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, GA, USA
    Am J Clin Nutr 81:746-50. 2005
    ..It is unclear how moderate and vigorous intensities of physical activity (PA) are associated with cardiovascular fitness (CVF) and percentage of body fat (%BF) in adolescents...
  59. ncbi Detection of glaucomatous visual field changes using the Moorfields regression analysis of the Heidelberg retina tomograph
    Stefano Miglior
    Department of Ophthalmology, University of Milan Bicocca, Milan, Italy
    Am J Ophthalmol 136:26-33. 2003
    To evaluate the sensitivity and specificity of optic disk examinations performed using the Moorfields regression analysis (MRA) of the Heidelberg Retina Tomograph (HRT) in differentiating normal from glaucomatous eyes.
  60. ncbi Waist circumference and not body mass index explains obesity-related health risk
    Ian Janssen
    Department of Community Health and Epidemiology, Queen s University, Kingston, Canada
    Am J Clin Nutr 79:379-84. 2004
    ..The addition of waist circumference (WC) to body mass index (BMI; in kg/m(2)) predicts a greater variance in health risk than does BMI alone; however, whether the reverse is true is not known...
  61. ncbi Female genital-tract HIV load correlates inversely with Lactobacillus species but positively with bacterial vaginosis and Mycoplasma hominis
    Beverly E Sha
    Department of Medicine, Section of Infectious Diseases, Rush University Medical Center, University of Illinois at Chicago, Illinois, USA
    J Infect Dis 191:25-32. 2005
    ..Bacterial vaginosis (BV) is associated with human immunodeficiency virus (HIV) acquisition. We examined the association between BV and BV-associated bacteria and expression of HIV in the female genital tract...
  62. doi Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis
    Brisa Simões Fernandes
    Bipolar Disorder Program, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil
    J Psychiatr Res 45:995-1004. 2011
    ..In euthymia, BDNF decreases with age and length of illness. These data suggest that peripheral BDNF could be used as a biomarker of mood states and disease progression for BD...
  63. pmc A brief conceptual tutorial on multilevel analysis in social epidemiology: investigating contextual phenomena in different groups of people
    Juan Merlo
    Department of Community Medicine, Lund University Hospital, S 205 02 Malmo, Sweden
    J Epidemiol Community Health 59:729-36. 2005
    1) To provide a didactic and conceptual (rather than mathematical) link between multilevel regression analysis (MLRA) and social epidemiological concepts...
  64. pmc Maternal smoking during pregnancy and childhood growth trajectory: a random effects regression analysis
    Kohta Suzuki
    Center for Birth Cohort Studies, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan
    J Epidemiol 22:175-8. 2012
    ..However, this analysis was limited because it rounded and categorized the age of the children. Therefore, we used a random-effects hierarchical linear regression model in the present study...
  65. ncbi Cumulative incidence in competing risks data and competing risks regression analysis
    Haesook T Kim
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Clin Cancer Res 13:559-65. 2007 compare cumulative incidence curves in the presence of competing risks, and to perform competing risks regression analysis. A hypothetical numeric example and real data are used to compare those three methods in the competing ..
  66. ncbi Increasing prevalence of Japanese cedar pollinosis: a meta-regression analysis
    Yoshihiro Kaneko
    Department of Public Health, Akita University School of Medicine, Akita, Japan
    Int Arch Allergy Immunol 136:365-71. 2005
    ..To confirm the increasing prevalence of Japanese cedar pollinosis and related factors, we conducted a meta-regression analysis on population-based surveys in Japan.
  67. ncbi Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Italy
    Diabetes Care 23:57-63. 2000
    ..To evaluate whether the homeostasis model assessment (HOMA) is a reliable surrogate measure of in vivo insulin sensitivity in humans...
  68. pmc Virologic and immunologic determinants of heterosexual transmission of human immunodeficiency virus type 1 in Africa
    S A Allen
    Department of Epidemiology and International Health, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    AIDS Res Hum Retroviruses 17:901-10. 2001
    ..FTM and MTF transmission rates were similar. These data suggest gender-specific differences in the biology of heterosexual transmission...
  69. doi Internal migration and health: re-examining the healthy migrant phenomenon in China
    Juan Chen
    Department of Applied Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong
    Soc Sci Med 72:1294-301. 2011
    ..These changes will lessen the pressure on big cities and improve the living conditions and opportunities of residents in townships/small cities and the countryside...
  70. pmc Nitrogen dioxide levels estimated from land use regression models several years apart and association with mortality in a large cohort study
    Giulia Cesaroni
    Department of Epidemiology, Lazio Regional Health Service, Via S, Costanza 53, 00198 Rome, Italy
    Environ Health 11:48. 2012
    ..We aimed to compare measured and estimated NO₂ levels 12 years apart, the stability of the exposure estimates for members of a large cohort study, and the association of the exposure estimates with natural mortality within the cohort...
  71. doi Heritability in the genomics era--concepts and misconceptions
    Peter M Visscher
    Queensland Institute of Medical Research, Royal Brisbane Hospital Post Office, Brisbane 4029, Queensland, Australia
    Nat Rev Genet 9:255-66. 2008
    ..Recent reports of substantial heritability for gene expression and new estimation methods using marker data highlight the relevance of heritability in the genomics era...
  72. doi Ambient air pollution, birth weight and preterm birth: a systematic review and meta-analysis
    David M Stieb
    Environmental Health Science and Research Bureau, Health Canada, 3rd Floor, 269 Laurier Ave W, Ottawa, ON, Canada K1A 0K9
    Environ Res 117:100-11. 2012
    ..While there is a large evidence base which is indicative of associations between CO, NO(2), PM and pregnancy outcome, variation in effects by exposure period and sources of heterogeneity between studies should be further explored...
  73. pmc Conditional variable importance for random forests
    Carolin Strobl
    Department of Statistics, Ludwig Maximilians Universitat Munchen, Ludwigstrasse 33, D 80539 Munchen, Germany
    BMC Bioinformatics 9:307. 2008
    ..Their variable importance measures have recently been suggested as screening tools for, e.g., gene expression studies. However, these variable importance measures show a bias towards correlated predictor variables...
  74. pmc Maternal cadmium exposure during pregnancy and size at birth: a prospective cohort study
    Maria Kippler
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 120:284-9. 2012
    ..Cadmium (Cd) is an embryotoxic and teratogenic metal in a variety of animal species, but data from humans are limited...
  75. doi Neuroanatomical abnormalities in schizophrenia: a multimodal voxelwise meta-analysis and meta-regression analysis
    Emre Bora
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Level 3, National Neuroscience Facility, Alan Gilbert Building, 161, Barry St, Carlton South, Vic, 3053, Australia
    Schizophr Res 127:46-57. 2011
    ..However, the available findings are biased towards characteristics of schizophrenia samples with poor prognosis...
  76. ncbi Prediction of protein B-factor profiles
    Zheng Yuan
    Institute for Molecular Bioscience and ARC Centre in Bioinformatics, The University of Queensland, St Lucia, Australia
    Proteins 58:905-12. 2005
    ..flexible). For almost all predicted B-factor thresholds, prediction accuracies (percent of correctly predicted residues) are greater than 70%. These results exceed the best results of other sequence-based prediction methods...
  77. ncbi The prediction of visceral fat by dual-energy X-ray absorptiometry in the elderly: a comparison with computed tomography and anthropometry
    M B Snijder
    Institute for Research in Extramural Medicine, Vrije Universiteit, Amsterdam, The Netherlands
    Int J Obes Relat Metab Disord 26:984-93. 2002
    ..The aim of the present study is to investigate whether the dual-energy X-ray absorptiometry (DXA) method, possibly combined with anthropometry, offers a good alternative to CT for the prediction of visceral fat in the elderly...
  78. pmc Association screening of common and rare genetic variants by penalized regression
    Hua Zhou
    Department of Statistics, North Carolina State University, Raleigh, NC 27695 8203, USA
    Bioinformatics 26:2375-82. 2010
    ..This article extends our recent research on penalized estimation methods in genome-wide association studies to the realm of rare variants...
  79. ncbi Dietary patterns and risk for type 2 diabetes mellitus in U.S. men
    Rob M van Dam
    Harvard School of Public Health, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts 02115, USA
    Ann Intern Med 136:201-9. 2002
    ..The role of diet in the development of type 2 diabetes mellitus remains unsettled...
  80. pmc Children's very low food security is associated with increased dietary intakes in energy, fat, and added sugar among Mexican-origin children (6-11 y) in Texas border Colonias
    Joseph R Sharkey
    School of Rural Public Health, Texas A and M Health Science Center, College Station, TX 77843 1266, USA
    BMC Pediatr 12:16. 2012
    ..This study assessed the relationship between children's experience of food insecurity and nutrient intake from food and beverages among Mexican-origin children (age 6-11 y) who resided in Texas border colonias...
  81. doi The effect of exercise-induced arousal on cognitive task performance: a meta-regression analysis
    Kate Lambourne
    Department of Kinesiology, The University of Georgia, Athens, GA 30602 6554, USA
    Brain Res 1341:12-24. 2010
    ..Cognitive performance may be enhanced or impaired depending on when it is measured, the type of cognitive task selected, and the type of exercise performed...
  82. ncbi Strategies to improve neuroreceptor parameter estimation by linear regression analysis
    Masanori Ichise
    Molecular Imaging Branch, National Institutes of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Cereb Blood Flow Metab 22:1271-81. 2002
    ..For tracers with slow kinetics and low to moderate noise, however, MA2 may provide the lowest bias while maintaining computational ease for pixelwise parameter estimation...
  83. pmc Multilevel support vector regression analysis to identify condition-specific regulatory networks
    Li Chen
    Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA
    Bioinformatics 26:1416-22. 2010
    ..New strategies are needed for reliable regulatory module identification...
  84. pmc Early determinants of physical activity in adolescence: prospective birth cohort study
    Pedro C Hallal
    Postgraduate Program in Epidemiology, Federal University of Pelotas, Duque de Caxias 250 3 piso 96030 002 Pelotas RS, Brazil
    BMJ 332:1002-7. 2006
    ..To examine the effects of early social, anthropometric, and behavioural variables on physical activity in adolescence...
  85. pmc Parenting styles, parenting practices, and physical activity in 10- to 11-year olds
    Russell Jago
    Centre for Exercise, Nutrition and Health Sciences, School for Policy Studies, University of Bristol, 8 Priory Road, Bristol BS8 1TZ, UK
    Prev Med 52:44-7. 2011
    ..The objective of this study was to determine whether parenting styles and practices are associated with children's physical activity...
  86. ncbi Explaining heterogeneity in meta-analysis: a comparison of methods
    S G Thompson
    Department of Medical Statistics and Evaluation, Imperial College School of Medicine, Hammersmith Hospital, Du Cane Road, London W12 0NN, U K
    Stat Med 18:2693-708. 1999
    ..Although such methods are preferable in principle, they often give similar results in practice...
  87. ncbi Centring in regression analyses: a strategy to prevent errors in statistical inference
    Helena C Kraemer
    Stanford University, Stanford, CA, USA
    Int J Methods Psychiatr Res 13:141-51. 2004
    ..Using non-centred data in regression analysis, which refers to the common practice of entering predictors in their original score format, often leads to ..
  88. ncbi Climate variations and bacillary dysentery in northern and southern cities of China
    Ying Zhang
    Department of Public Health, University of Adelaide, Level 9, 10 Pulteney Street, Adelaide, SA5005, Australia
    J Infect 55:194-200. 2007
    ..This paper was aimed at examining the relationship between meteorological variables and bacillary dysentery in different climatic and geographic areas in China...
  89. ncbi Regression models for relative survival
    Paul W Dickman
    Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
    Stat Med 23:51-64. 2004
  90. pmc Reproducing kernel hilbert spaces regression methods for genomic assisted prediction of quantitative traits
    Daniel Gianola
    Department of Animal Sciences, University of Wisconsin, Madison, Wisconsin 53706, USA
    Genetics 178:2289-303. 2008
    ..Models for capturing different forms of interaction, e.g., chromosome-specific, are presented. Implementations can be carried out using software for likelihood-based or Bayesian inference...
  91. pmc Short term effects of temperature on risk of myocardial infarction in England and Wales: time series regression analysis of the Myocardial Ischaemia National Audit Project (MINAP) registry
    Krishnan Bhaskaran
    Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT
    BMJ 341:c3823. 2010
    ..To examine the short term relation between ambient temperature and risk of myocardial infarction...
  92. ncbi Allometric scaling of mammalian metabolism
    Craig R White
    School of Earth and Environmental Sciences, The University of Adelaide, Adelaide, SA, 5005 Australia
    J Exp Biol 208:1611-9. 2005
    ..Clearly the value of the exponent depends on the conditions under which the data are selected. The exponent for true BMR is 0.686 (+/-0.014), Tb normalised SMR is 0.675 (+/-0.013) and RMRt is 0.712 (+/-0.013)...
  93. ncbi Estimation of contribution of changes in coronary care to improving survival, event rates, and coronary heart disease mortality across the WHO MONICA Project populations
    H Tunstall-Pedoe
    Cardiovascular Epidemiology Unit, MONICA Quality Control Centre for Event Registration, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
    Lancet 355:688-700. 2000
    ..The revolution in coronary care in the mid-1980s to mid-1990s corresponded with monitoring of coronary heart disease (CHD) in 31 populations of the WHO MONICA Project. We studied the impact of this revolution on coronary endpoints...
  94. pmc Nonparametric methods for incorporating genomic information into genetic evaluations: an application to mortality in broilers
    Oscar González-Recio
    Departamento de Produccion Animal, E T S I Agrónomos Universidad Politécnica de Madrid, 28040 Madrid, Spain
    Genetics 178:2305-13. 2008
    ..Predictive ability, assessed by cross-validation, indicated advantages of the RKHS approach, where accuracy was increased from 25 to 150%, relative to other methods...
  95. ncbi Individual-level modifiers of the effects of particulate matter on daily mortality
    Ariana Zeka
    Environmental Health Department, Harvard School of Public Health, 401 Park Drive, Suite 415 West, Boston, MA 02215, USA
    Am J Epidemiol 163:849-59. 2006
    ..The findings suggest that more attention must be paid to population characteristics to identify greater likelihood of exposures and susceptibility and, as a result, to improve policy making for air pollution standards...
  96. doi Trends in hip fracture rates in Canada
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    JAMA 302:883-9. 2009
    ..Hip fractures are a public health concern because they are associated with significant morbidity, excess mortality, and the majority of the costs directly attributable to osteoporosis...
  97. ncbi Regression analysis of restricted mean survival time based on pseudo-observations
    Per Kragh Andersen
    Department of Biostatistics, University of Copenhagen, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Lifetime Data Anal 10:335-50. 2004
    Regression models for survival data are often specified from the hazard function while classical regression analysis of quantitative outcomes focuses on the mean value (possibly after suitable transformations)...
  98. ncbi Long-term trends in cancer mortality in Korea (1983-2007): a joinpoint regression analysis
    Kyu Won Jung
    National Cancer Control Institute, National Cancer Center, Goyang, Korea
    Asian Pac J Cancer Prev 11:1451-7. 2010
  99. pmc The impact of heat waves and cold spells on mortality rates in the Dutch population
    M M Huynen
    International Centre for Integrative Studies, Maastricht University, Maastricht, The Netherlands
    Environ Health Perspect 109:463-70. 2001
    ..The results concerning the forward displacement of deaths due to heat waves were not conclusive. We found no cold-induced forward displacement of deaths...
  100. ncbi Impact of age on QT interval and QT dispersion in healthy subjects: a regression analysis
    Arduino A Mangoni
    Department of Health Care of the Elderly, Guy s, King s, and St Thomas School of Medicine, King s College London, UK
    Age Ageing 32:326-31. 2003
    ..We studied the effects of age, gender, body mass index, smoking status, and blood pressure on these electrocardiographic parameters...
  101. ncbi Prognostic modeling with logistic regression analysis: in search of a sensible strategy in small data sets
    E W Steyerberg
    Department of Public Health, Erasmus University, Rotterdam, The Netherlands
    Med Decis Making 21:45-56. 2001
    ..In conclusion, a sensible strategy in small data sets is to apply shrinkage methods in full models that include well-coded predictors that are selected based on external information...

Research Grants78

  1. Cardiac Troponin Testing for Myocardial Infarction
    Fred Apple; Fiscal Year: 2001
    ..Clinical performance of each cardiac marker assay (using logistic multiple regression analysis) will also be assessed for its ability to assess cardiac events (AMI, cardiac related death) during ..
  2. Comparison of Diesel and Biodiesel Emissions and Health Effects in Underground Mi
    Jefferey L Burgess; Fiscal Year: 2013
    ..For each fuel type, regression analysis will be used to model the effects of emissions contaminants on pre- to post-exposure changes in individual ..
  3. Predicting Bilirubin-induced Auditory Toxicity in Infants with Severe Jaundice
    Sanjiv B Amin; Fiscal Year: 2010
    ..Rigorous standardization across centers and protocols to monitor sample transport are in place. Regression analysis will be performed to evaluate the strength of association between unbound bilirubin and auditory toxicity...
  4. Statins &Lymphoid Malignancy Risk in a Large Multi-Site Population-Based Cohort
    Marianne Ulcickas Yood; Fiscal Year: 2013
    ..Conditional logistic regression analysis will be used to address aim 1;statin users will be compared both to non-users and to users of other ..
  5. Predictors of Dietary Quality in Low-Income Pregnant Women
    Eileen R Fowles; Fiscal Year: 2010
    ..Descriptive, correlation, and regression analysis will be conducted to address the specific aims of the study...
  6. A novel allele influencing HIV infection among injection drug users
    Xiao Fang Yu; Fiscal Year: 2012
    ..2-7.5]). Furthermore, multiple regression analysis revealed significant positive associations between A3B expression and viral load set-points...
  7. Impact of Temperature Profile on Outcome After Traumatic Brain Injury
    Lori Kennedy Madden; Fiscal Year: 2013
    ..validate findings and identify potential implications for future research nursing practice Multiple ordinal regression analysis will be used to estimate the relative contribution of IMPACT variables (age, GCS motor score, pupillary ..
  8. Assessment of Dehydration in Children with Diarrhea in Resource-Limited Settings
    ADAM CARL LEVINE; Fiscal Year: 2013
    ..However, I would benefit from additional targeted training in specific areas, including advanced regression analysis and recursive partitioning, clinical trial design and management, cost- effectiveness analysis, the ..
  9. Nutrition and Physical Activity Assessment Study (NPAAS)
    Ross L Prentice; Fiscal Year: 2013
    ..develop calibration equations for each nutrient/food or activity measure having a suitable biomarker, by regression analysis of the biomarker on corresponding self-report measures using specimens and data from the women in both ..
  10. Prenatal stress biology, infant body composition and obesity risk
    Sonja Entringer; Fiscal Year: 2013
    ..additive models, polynomial distributed lag, classification and regression trees, and multivariate regression analysis will be used to address the study aims...
  11. Biomarker of Tissue Tolerance and Behavior in a Rat Model of WMSD
    Mary F Barbe; Fiscal Year: 2013
    ..To determine the association between serum and behavioral variables, a multiple regression analysis will be used. The 2 experimental groups will perform either the MRLF or HRHF task for 16 or 22 weeks...
  12. Home ECG Monitoring to Detect Allograft Rejection Following Heart Transplantation
    Barbara J Drew; Fiscal Year: 2013
    ..For Primary Aim #1, a log regression analysis will be performed with the 23 independent variable being presence /absence of the ECG criteria ( QTC e25 ..
  13. FT-IR Microscopy of Mineral Structure
    Adele L Boskey; Fiscal Year: 2013
    ..We have recently shown by multiple logistic regression analysis that specific mineral and matrix properties assessed by Fourier transform infrared spectroscopic imaging (..
  14. Risk of death among veterans with depression
    Kara Zivin; Fiscal Year: 2013
    ..We will use survival analysis techniques, specifically Cox regression models, as well as logistic regression analysis to examine the impact of depression on timing and causes of death in our VA patient cohort...
  15. Early Life Nutritional Environments and Cognitive Ability in Children
    Rika Tanda; Fiscal Year: 2012
    ..b>Regression analysis will be used to examine the association between cognitive test scores and a quadratic function of birth ..
  16. Pre-existing Diabetes and Pregnancy
    Caitlin A Knox; Fiscal Year: 2013
    ..anti-diabetic agent utilization, linear regression to evaluate secular trends, and multivariate logistic regression analysis to determine the comparative safety of oral anti-diabetic agents in relation to cesarean section delivery, ..
  17. Impact of Family History of Colon Cancer on Adenomas in 40-49 Year Olds
    Philip S Schoenfeld; Fiscal Year: 2012
    ..adenomas (any size) among 40-49 year old individuals with a family history of CRC using multiple logistic regression analysis. METHODS: This is a multi-center, prospective cohort study conducted at four sites (Ann Arbor VAHS, Durham ..
  18. Obesity, Muscle Strength, and Disability in Older Mexican Americans and Elders fr
    Soham Al Snih; Fiscal Year: 2010
    ..Multiple regression analysis will be used to test the association between obesity and muscle strength...
  19. Early Acute Lung Injury: Prospective Evaluation Prior to Respiratory Failure
    Joseph Levitt; Fiscal Year: 2013
    ..Biomarkers will be analyzed by multivariate regression analysis to assess their value for stratifying patients at risk for progression to ALI and provide mechanistic ..
  20. Oral Health Disparities Among Medicaid Beneficiaries
    Sujha Subramanian; Fiscal Year: 2010
    ..We will also generate the annual percentage change and perform joinpoint regression analysis to identify points where a significant change in the linear slope of the trend occurs...
  21. Cortical GABA in MDD and Primary Insomnia with Magnetic Resonance Spectroscopy
    John W Winkelman; Fiscal Year: 2013
    ..We will also use regression analysis to correlate PSG and sleep diary information, with 1H-MRS-derived GABA data.
  22. Validating NIAAA screening guide in YCMC - administrative supplement
    Elissa R Weitzman; Fiscal Year: 2013
    ..We will use Generalized Estimating Equations logistic regression analysis to identify significant differences among those with problem use, abuse and dependence vs...
  23. Exploring Specific Metabolic Rates of Major Cell Categories in Adiposity-Diverse
    ZiMian Wang; Fiscal Year: 2010
    ..We will address the Ji values by using multiple linear regression analysis with REE as the dependent variable, and Ci as the independent variables...
  24. Biodemography of Disease and Death in Moscow
    James W Vaupel; Fiscal Year: 2010
    ..We propose to study these data, using standard statistical methods of regression analysis, with a focus on determining the incremental value of Holter monitoring as an additional source of ..
  25. Pain Assessment & Intervention Needs (PAIN)
    Fern Fitzhenry; Fiscal Year: 2010
    ..The study will use a regression analysis to examine the outcome of implemented pain standards on the level of pain experienced by the patient during ..
  26. EMA Assessment of Biobehavioral Processes in Human Pregnancy
    Pathik D Wadhwa; Fiscal Year: 2013 computed by methods including subject-specific auto-regression models, and multivariate and longitudinal regression analysis will be employed to test the specific aims and hypotheses using generalizing estimating equations (GEE) and ..
  27. MR Imaging of the Excitatory and Inhibitory Neurotransmitters in Chronic Pain
    Bradley Foerster; Fiscal Year: 2013
    ..A cross-sectional regression analysis will be used to assess the association of Glx and GABA with subject group (central pain predominant, ..
  28. Energy Balance, IGF Dysregulation and Multiple Myeloma
    Brenda M Birmann; Fiscal Year: 2010
    ..We will conduct conditional logistic regression analysis to estimate the association of obesity, adult weight gain, physical activity, and prediagnostic plasma ..
  29. Mesenchymal stromal cells and bronchopulmonary dysplasia
    ANTONIA PETROVA POPOVA; Fiscal Year: 2013
    ..protein expression and mesenchymal stromal cell gene expression will be calculated using multivariate regression analysis. Training Objectives: Acquire experience and understanding in the areas of experimental design, statistics, ..
    Judith S Brook; Fiscal Year: 2011
    ..The primary analytic techniques will be causal analysis, logistic regression analysis, and growth mixture modeling...
  31. Defining the genetic architecture of IBD in Ashkenazi Jewish populations
    Judy H Cho; Fiscal Year: 2013
    ..Refined definitions of associated alleles through regression analysis and functional annotation, together with interrogation of weaker effect alleles, will result in an ..
  32. Prenatal pyrethroid exposure and child mental, motor and behavioral development
    ROBIN MARJORIE WHYATT; Fiscal Year: 2013
    ..Multiple linear regression analysis will be used to examine associations between the pyrethroid metabolites and outcomes, adjusting for ..
  33. Statins and prostate cancer recurrence
    Sheila A Weinmann; Fiscal Year: 2012
    ..We will use propensity score modeling and Cox regression analysis to evaluate these questions, adjusting for pathologic and clinical factors as appropriate...
  34. Single-cell analysis of TNF-induced signaling, transcription and fate decisions
    Suzanne Gaudet; Fiscal Year: 2013
    ..Using multivariable regression analysis of our data from Aim 1 we will build models connecting both extracellular cues and intracellular signals to ..
  35. CVD Risk in Minority Populations w/ and w/o Type 2 Diabetes: Haitian and Black
    Fatma G Huffman; Fiscal Year: 2011
    ..between groups and the significant predictors of CVD in this population using multiple and logistical regression analysis. Results of this study will address at least two of the objectives of the Healthy People 2010 with regard ..
  36. Atlas-Based Structural Models of the Mouse Myocardium
    Edward W Hsu; Fiscal Year: 2012 investigate the gender and genotype-dependence of mouse heart structural atlases, (2c) combine group regression analysis and diffeomorphic mapping to investigate the maturational adaptive modulation of the normal mouse heart, ..
  37. The Impact of Early Access to Oral Contraception on the Health of Women and Child
    DANIEL HUNGERMAN; Fiscal Year: 2010
    ..Using regression analysis on data taken from a number of readily available sources, the investigators will exploit this variation in ..
  38. Shoulder Pain in Spinal Cord Injury (SCI): A Longitudinal Study
    Sara J Mulroy; Fiscal Year: 2010
    ..Using logistic regression analysis we will determine the odds ratios for the vertical shoulder joint reaction force during WCP, shoulder ..
  39. Assessing Health Effects and Risk Factors after Hurricane Sandy in NYS
    Shao Lin; Fiscal Year: 2013
    ..and the control areas (unaffected by Sandy in the same county and similar SES) using unconditional logistic regression analysis in a retrospective cohort study...
  40. Assessing Workplace Phthalate Exposures Among Massage Therapy Students
    VICTORIA PAK; Fiscal Year: 2010
    ..will involve descriptive statistics, spearman coefficient correlations, and stepwise multiple linear regression analysis. This knowledge will be useful for understanding further the sources and extent of exposures among massage ..
  41. A Longitudinal Study of the Predictors of Smoking in Women in Late Midlife
    Judith S Brook; Fiscal Year: 2012
    ..The primary analytic techniques will be causal analysis, logistic regression analysis, and growth mixture modeling...
  42. Work Outcomes of Colon and Rectal Cancer Survivors
    Carolyn Y Fang; Fiscal Year: 2012
    ..For hypothesis 1, multiple regression analysis will be performed separately for each diagnosis and each work outcome: work status, work intensity, time to ..
  43. Statistical Methods for Next-Generation Sequence Data
    HONGZHE LEE; Fiscal Year: 2013
    ..wavelet-based nonparametric regression and nonparametric hypothesis testing and penalized regression analysis for tree-structured covariates...
  44. Effects of general vs. regional anesthesia on infant neurodevelopment and apnea
    Mary Ellen McCann; Fiscal Year: 2013
    ..Multiple linear or logistic regression analysis, adjusting for potential confounders, will be used to estimate treatment group differences...
  45. ANtecedents and outcomes of self-care in adults with congenital heart disease
    Nancy McCabe; Fiscal Year: 2013
    ..Descriptive, correlation, and regression analysis will be used to statistically evaluate specific aims...
  46. The implementation of a pharmacogenomics-based algorithm for warfarin dosing
    Minoli Perera; Fiscal Year: 2013
    ..b>Regression analysis will be used to derive a dosing algorithm to predict maintenance dose...
  47. Outcomes, Costs and Trends in Dialysis Timing in VA
    ANN M O'HARE; Fiscal Year: 2013
    ..Using descriptive statistics and regression analysis, we will compare trends in early initiation of dialysis (measured by eGFR at dialysis) for VA versus non-VA ..
  48. Adherence and the Economics of Colon Cancer Screening
    John Inadomi; Fiscal Year: 2009
    ..Analytic methods will include Chi-square testing of proportions, linear mixed-effects modeling and logistic regression analysis. PCPs will be examined as random- and fixed-effects in separate models to account for potential clustering ..
  49. Evaluation of Value-Based Health Plan Design
    DAVID CAMPBELL GROSSMAN; Fiscal Year: 2013
    ..We will use regression analysis to estimate the impact of Total Health on outcomes assessed via the survey of employees as well as outcomes ..
  50. EHR use and care coordination
    Ilana Graetz; Fiscal Year: 2011
    ..Using multivariate regression analysis, I will examine the association between EHR use and care coordination, while adjusting for clinician ..
  51. Community/Worker Exposures to Pathogens from Industrial Food Animal Production
    Ellen K Silbergeld; Fiscal Year: 2012
    ..geospatial methods to investigate person-to-person contact and proximity factors, and multivariate regression analysis to identify other risk factors...
  52. Genetic risk factors in African American colorectal cancer patients
    Nathan A Ellis; Fiscal Year: 2013
    ..We will use 100 ancestry informative markers to perform a structured logistic regression analysis that takes into account possible population stratification based on ancestry...
  53. Effective Communication Network Structures for Hospital Infection Prevention
    Pavani Rangachari; Fiscal Year: 2011
    ..on CLBSI practices;network analysis of communication network structures (alongside unit outcomes);and regression analysis of the relationship between communication network structures and outcomes...
  54. Specialized Treatment Early in Psychosis (STEP): A community health center based
    Vinod H Srihari; Fiscal Year: 2010
    ..groups will be compared at baseline and significant differences will be entered into the logistic regression analysis. Time to event data, such a time to first new hospitalization after randomization, will be analyzed using ..
  55. Predicting Morbidity from Pediatric Critical Care
    MURRAY MICHAEL POLLACK; Fiscal Year: 2013
    ..both "simple" linear models with the FSS contributing the gradations of outcome, and polychotomous logistic regression analysis for models of 3 or more discrete outcome states...
  56. Novel Biomarkers in Ovarian Cancer
    Michael Birrer; Fiscal Year: 2013
    ..Using transcriptional profiling technology combined with Cox regression analysis, we have previously identified a putative gene signature, which can predict survival in patients with ..
  57. Palliation of Thirst in Intensive Care Unit Patients
    Kathleen A Puntillo; Fiscal Year: 2011
    ..Multiple logistic regression analysis and multiple linear regression analysis will be used to determine association of risk factors with the ..
  58. Cohort analysis methods for occupational cancer studies
    David B Richardson; Fiscal Year: 2012
    ..This work showed that there are many settings in which standard regression analysis yielded strongly biased effect measures...
  59. MRI-Based Modeling to Evaluate Surgical Efficacy for Reduced OA Risk
    Kenneth J Fischer; Fiscal Year: 2012
    ..b>Regression analysis will also be performed between all contact mechanics measures and dGEMRIC values, pain levels and grip ..
  60. Training Doctors to Disclose Unanticipated Outcomes to Patients: Randomized Trial
    THOMAS HENRY GALLAGHER; Fiscal Year: 2011
    ..Multivariate regression analysis will also be used to examine the effects of patient, event, and physician characteristics on patient ..
  61. Secondary Bacteremia in Patients with Catheter-Associated Urinary Tract Infection
    LAURIE JEAN CONWAY; Fiscal Year: 2013
    ..Cases and controls will be matched on severity of illness and age within 10 years. Multivariate regression analysis will be employed to examine the independent effects of multiple concurrent risk factors (i.e...
  62. Latent variable analysis in cognitive aging and executive function
    ..Unlike regression analysis, latent variable analysis (LVA) methods can increase precision by explicitly modeling measurement error, ..
  63. Changes in proximal tibia fracture strength as a function of time elapsed since s
    William Brent Edwards; Fiscal Year: 2012
    ..models will be derived from CT data, and their ability to predict fracture strength determined from a regression analysis of numerical and experimental fracture loads...
  64. Building Disease Prediction Models by Synthesis Analysis
    XIAO HUA A ZHOU; Fiscal Year: 2010
    ..A risk prediction model on a disease outcome may be obtained through multivariate regression analysis of a longitudinal study...
  65. Neuropsychological & Thyroid Effects of Perfluorinated Compounds in Older Adults
    Edward Fitzgerald; Fiscal Year: 2009
    ..variables (including serum concentrations of organochlorine pesticides, blood lead and mercury), multiple regression analysis will be used...
    David Harpole; Fiscal Year: 2000
    ..will be used to develop a prediction rule for recurrence in stage I NSCLC using Cox proportional hazards regression analysis and an artificial neural network...
  67. Risk Factors for Late Life Anxiety
    JOHN CALAMARI; Fiscal Year: 2006
    ..In the three proposed studies, we use sequential regression analysis and path analysis to test whether specific, malleable psychological characteristics (affective traits) ..
    Joel Grube; Fiscal Year: 1993
    ..will be addressed through a series of bivariate and multivariate analyses including profile analysis, regression analysis, discriminant function analysis, and multi-group structural equation modeling...
    Qingyi Wei; Fiscal Year: 2000
    ..Logistic regression analysis will be used to adjust for possible confounding effects of other known risk factors such as family history ..
  70. DNA repair-based models of glioblastoma response to radiation and temozolomide
    JOHN SILBER; Fiscal Year: 2009
    ..We will use Cox regression analysis to examine the association between Ap endo activity and PFS in multivariate models that include MGMT ..
    Fredric Frigoletto; Fiscal Year: 1993
    ..Potential confounding and modifying variables will be controlled using multivariate logistic regression analysis. A variety of other obstetrical endpoints will be evaluated including length of labor, use of oxytocin, ..
  72. Inflammation and Infection as Risk Factors in Stroke
    Mitchell Elkind; Fiscal Year: 2006
    ..Multiple conditional logistic regression analysis will be used to assess the significance of the main exposure variables after matching for age, gender, and ..
    Susan Payne; Fiscal Year: 1993 predict intensity (skilled provider time in minutes) and visit-related costs will be developed using regression analysis, with characteristics of the client, nurse, agency, and visit as the independent variables...
  74. Disparities in Child & Family Health Care Expenditures
    Paul Newacheck; Fiscal Year: 2003
    ..Also using the 1997 MEPS, a hierarchical regression analysis will be used to assess whether health insurance is associated with a diminution of income and racial/ethnic ..
  75. Sociodemographics and HRQL: Mapping the SF-12 and EQ-5D
    Erica Lubetkin; Fiscal Year: 2003
    ..The four dependent variables for each regression analysis will be the PCS-12, MCS-12, EQ-5D index, and EQ VAS...
    A Tussing; Fiscal Year: 1990
    Multiple regression analysis will be used to test the hypothesis that the recent dramatic increases in the U.S. cesarean rate is due in art to economic factors...
    TIMOTHY NORMAN; Fiscal Year: 2000
    ..Using multiple regression analysis, the most important properties for predicting fracture toughness will be identified...
  78. Noninvasive Quantification of the Resistance Baroeflex
    Ramakrishna Mukkamala; Fiscal Year: 2006
    ..While multiple regression analysis (MRA) can determine the closed-loop gain values of both systems, this analysis mandates a sophisticated ..