predictive value of tests

Summary

Summary: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.

Top Publications

  1. ncbi Gene expression profiling predicts clinical outcome of breast cancer
    Laura J van 't Veer
    Division of Diagnostic Oncology, The Netherlands Cancer Institute, 121 Plesmanlaan, 1066 CX Amsterdam, The Netherlands
    Nature 415:530-6. 2002
  2. ncbi Prediction of plant microRNA targets
    Matthew W Rhoades
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, MA 02142, USA
    Cell 110:513-20. 2002
  3. ncbi A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C
    Chun Tao Wai
    Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Hepatology 38:518-26. 2003
  4. ncbi The diagnostic odds ratio: a single indicator of test performance
    Afina S Glas
    Department of Clinical Epidemiology and Biostatistics, University of Amsterdam, Academic Medical Center, Post Office Box 22700, 100 DE Amsterdam, The Netherlands
    J Clin Epidemiol 56:1129-35. 2003
  5. ncbi Prediction of mammalian microRNA targets
    Benjamin P Lewis
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Cell 115:787-98. 2003
  6. ncbi Expert consensus document on arterial stiffness: methodological issues and clinical applications
    Stephane Laurent
    Department of Pharmacology and Hôpital Européen Georges Pompidou, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, INSERM U652, 20 rue Leblanc, 75015 Paris, France
    Eur Heart J 27:2588-605. 2006
  7. ncbi Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis
    Matthias W Lorenz
    Johann Wolfgang Goethe University, Department for Neurology, Schleusenweg 2 16, D 60528 Frankfurt Main, Germany
    Circulation 115:459-67. 2007
  8. doi Ki67 in breast cancer: prognostic and predictive potential
    Rinat Yerushalmi
    Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    Lancet Oncol 11:174-83. 2010
  9. ncbi Prognostic and predictive factors in breast cancer by immunohistochemical analysis
    D C Allred
    Department of Pathology, University of Texas Health Science Center, San Antonio 78284, USA
    Mod Pathol 11:155-68. 1998
  10. ncbi Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men
    Youfa Wang
    Department of Human Nutrition and Division of Epidemiology and Biostatistics, University of Illinois at Chicago, USA
    Am J Clin Nutr 81:555-63. 2005

Detail Information

Publications347 found, 100 shown here

  1. ncbi Gene expression profiling predicts clinical outcome of breast cancer
    Laura J van 't Veer
    Division of Diagnostic Oncology, The Netherlands Cancer Institute, 121 Plesmanlaan, 1066 CX Amsterdam, The Netherlands
    Nature 415:530-6. 2002
    ..This gene expression profile will outperform all currently used clinical parameters in predicting disease outcome. Our findings provide a strategy to select patients who would benefit from adjuvant therapy...
  2. ncbi Prediction of plant microRNA targets
    Matthew W Rhoades
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, MA 02142, USA
    Cell 110:513-20. 2002
    ..The targeting of developmental transcription factors suggests that many plant miRNAs function during cellular differentiation to clear key regulatory transcripts from daughter cell lineages...
  3. ncbi A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C
    Chun Tao Wai
    Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Hepatology 38:518-26. 2003
    ..Application of this index may decrease the need for staging liver biopsy specimens among CHC patients...
  4. ncbi The diagnostic odds ratio: a single indicator of test performance
    Afina S Glas
    Department of Clinical Epidemiology and Biostatistics, University of Amsterdam, Academic Medical Center, Post Office Box 22700, 100 DE Amsterdam, The Netherlands
    J Clin Epidemiol 56:1129-35. 2003
    ..A disadvantage is the impossibility of weighing the true positive and false positive rate separately. In this article the application of the diagnostic odds ratio in test evaluation is illustrated...
  5. ncbi Prediction of mammalian microRNA targets
    Benjamin P Lewis
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Cell 115:787-98. 2003
    ..The predicted regulatory targets of mammalian miRNAs were enriched for genes involved in transcriptional regulation but also encompassed an unexpectedly broad range of other functions...
  6. ncbi Expert consensus document on arterial stiffness: methodological issues and clinical applications
    Stephane Laurent
    Department of Pharmacology and Hôpital Européen Georges Pompidou, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, INSERM U652, 20 rue Leblanc, 75015 Paris, France
    Eur Heart J 27:2588-605. 2006
    ....
  7. ncbi Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis
    Matthias W Lorenz
    Johann Wolfgang Goethe University, Department for Neurology, Schleusenweg 2 16, D 60528 Frankfurt Main, Germany
    Circulation 115:459-67. 2007
    ..Its use relies on its ability to predict future clinical cardiovascular end points. We performed a systematic review and meta-analysis of data to examine this association...
  8. doi Ki67 in breast cancer: prognostic and predictive potential
    Rinat Yerushalmi
    Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    Lancet Oncol 11:174-83. 2010
    ....
  9. ncbi Prognostic and predictive factors in breast cancer by immunohistochemical analysis
    D C Allred
    Department of Pathology, University of Texas Health Science Center, San Antonio 78284, USA
    Mod Pathol 11:155-68. 1998
    ..In the future, these and other factors will be incorporated into a prognostic index that will better reflect the biologic diversity of breast cancer and that will more accurately predict clinical outcome...
  10. ncbi Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men
    Youfa Wang
    Department of Human Nutrition and Division of Epidemiology and Biostatistics, University of Illinois at Chicago, USA
    Am J Clin Nutr 81:555-63. 2005
    ..However, few studies have compared the predictive power of overall obesity with that of central obesity. The cutoffs for waist circumference (WC) and waist-to-hip ratio (WHR) as measures of abdominal adiposity remain controversial...
  11. pmc Shortened Modified Look-Locker Inversion recovery (ShMOLLI) for clinical myocardial T1-mapping at 1.5 and 3 T within a 9 heartbeat breathhold
    Stefan K Piechnik
    University of Oxford Centre for Clinical Magnetic Resonance Research, Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, UK
    J Cardiovasc Magn Reson 12:69. 2010
    ..In this work we propose and validate a novel, clinically applicable, pulse sequence for myocardial T1-mapping that is compatible with typical limits for end-expiration breath-holding in patients...
  12. ncbi Waist circumference and not body mass index explains obesity-related health risk
    Ian Janssen
    Department of Community Health and Epidemiology, Queen s University, Kingston, Canada
    Am J Clin Nutr 79:379-84. 2004
    ..The addition of waist circumference (WC) to body mass index (BMI; in kg/m(2)) predicts a greater variance in health risk than does BMI alone; however, whether the reverse is true is not known...
  13. ncbi The diabetes risk score: a practical tool to predict type 2 diabetes risk
    Jaana Lindström
    Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
    Diabetes Care 26:725-31. 2003
    ..Interventions to prevent type 2 diabetes should be directed toward individuals at increased risk for the disease. To identify such individuals without laboratory tests, we developed the Diabetes Risk Score...
  14. ncbi Modified glomerular filtration rate estimating equation for Chinese patients with chronic kidney disease
    Ying Chun Ma
    Division of Nephrology and Institute of Nephrology, The First Hospital, Peking University, No 8 Xishiku Street, Xicheng District, Beijing 100034, PR China
    J Am Soc Nephrol 17:2937-44. 2006
    ..The modified MDRD equations that were based on the Chinese patients with CKD offered significant advantages in different CKD stages and could be applied in clinical practice, at least in Chinese patients with CKD...
  15. pmc The molecular portraits of breast tumors are conserved across microarray platforms
    Zhiyuan Hu
    Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA
    BMC Genomics 7:96. 2006
    ..To overcome this problem we used publicly available breast cancer gene expression data sets and a novel approach to data fusion, in order to validate a new breast tumor intrinsic list...
  16. pmc Cardiovascular magnetic resonance and single-photon emission computed tomography for diagnosis of coronary heart disease (CE-MARC): a prospective trial
    John P Greenwood
    Multidisciplinary Cardiovascular Research Centre and Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK
    Lancet 379:453-60. 2012
    ....
  17. doi Development and first validation of the COPD Assessment Test
    P W Jones
    St George s University of London, UK
    Eur Respir J 34:648-54. 2009
    ..It has good measurement properties, is sensitive to differences in state and should provide a valid, reliable and standardised measure of COPD health status with worldwide relevance...
  18. pmc Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer
    J Joshua Smith
    Department of Surgery, Vanderbilt Medical Center, Nashville, TN, USA
    Gastroenterology 138:958-68. 2010
    ..We used a gene expression profile derived from invasive, murine colon cancer cells that were highly metastatic in an immunocompetent mouse model to identify patients with colon cancer at risk of recurrence...
  19. ncbi Internal validation of predictive models: efficiency of some procedures for logistic regression analysis
    E W Steyerberg
    Center for Clinical Decision Sciences, Ee 2091, Department of Public Health, Erasmus University, P O Box 1738, 3000 DR, Rotterdam, The Netherlands
    J Clin Epidemiol 54:774-81. 2001
    ..We conclude that split-sample validation is inefficient, and recommend bootstrapping for estimation of internal validity of a predictive logistic regression model...
  20. ncbi International staging system for multiple myeloma
    Philip R Greipp
    Mayo Clinic College of Medicine and Eastern Cooperative Oncology Group, Rochester, MN, USA
    J Clin Oncol 23:3412-20. 2005
    ..There is a need for a simple, reliable staging system for multiple myeloma that can be applied internationally for patient classification and stratification...
  21. pmc Myocardial T1 and extracellular volume fraction mapping at 3 tesla
    Jason J Lee
    Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA
    J Cardiovasc Magn Reson 13:75. 2011
    ..To compare 11 heartbeat (HB) and 17 HB modified lock locker inversion recovery (MOLLI) pulse sequence at 3T and to establish preliminary reference values for myocardial T1 and the extracellular volume fraction (ECV)...
  22. ncbi Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study
    F Imbert-Bismut
    Department of Biochemistry, , Paris, France
    Lancet 357:1069-75. 2001
    ..60 to 1.00 (34% [115] of all patients). INTERPRETATION: A combination of basic serum markers could be used to substantially reduce the number of liver biopsies done in patients with chronic HCV infection...
  23. ncbi Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection
    Richard K Sterling
    Section of Hepatology, Virginia Commonwealth University Health System, Richmond, VA 23298 0341, USA
    Hepatology 43:1317-25. 2006
    ..In conclusion, noninvasive tests can accurately predict hepatic fibrosis and may reduce the need for liver biopsy in the majority of HIV/HCV-coinfected patients...
  24. doi Diagnostic performance of coronary angiography by 64-row CT
    Julie M Miller
    Johns Hopkins University School of Medicine, Baltimore 21287, USA
    N Engl J Med 359:2324-36. 2008
    ..The accuracy of multidetector computed tomographic (CT) angiography involving 64 detectors has not been well established...
  25. ncbi Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery
    Jaya Mishra
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
    Lancet 365:1231-8. 2005
    ..We tested the hypothesis that neutrophil gelatinase-associated lipocalin (NGAL) is an early biomarker for ischaemic renal injury after cardiopulmonary bypass...
  26. pmc An automated method for finding molecular complexes in large protein interaction networks
    Gary D Bader
    Samuel Lunenfeld Research Institute, MT, Sinai Hospital, Toronto ON Canada M5G 1X5, Dept, of Biochemistry, University of Toronto, Toronto ON Canada M5S 1A8
    BMC Bioinformatics 4:2. 2003
    ..As the size of the interaction set increases, databases and computational methods will be required to store, visualize and analyze the information in order to effectively aid in knowledge discovery...
  27. ncbi Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study
    Francesco U S Mattace-Raso
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Circulation 113:657-63. 2006
    ..We evaluated whether arterial stiffness is a predictor of coronary heart disease and stroke in a population-based study among apparently healthy subjects...
  28. pmc An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival
    Lance D Miller
    Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672
    Proc Natl Acad Sci U S A 102:13550-5. 2005
    ..Our results show the primary importance of p53 functional status in predicting clinical breast cancer behavior...
  29. pmc Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study
    Naomi M Hamburg
    Cardiology Section, Whitaker Cardiovascular Institute, School of Medicine, Boston University, Boston, Mass 01702, USA
    Circulation 117:2467-74. 2008
    ..Baseline digital pulse amplitude reflects local peripheral arterial tone. The relation of digital pulse amplitude and digital hyperemic response to cardiovascular risk factors in the community is unknown...
  30. doi Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Endorsed by the Society for Vascula
    James H Stein
    University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    J Am Soc Echocardiogr 21:93-111; quiz 189-90. 2008
  31. ncbi Meta-analysis of risk factors for posttraumatic stress disorder in trauma-exposed adults
    C R Brewin
    Subdepartment of Clinical Health Psychology, University College London, England
    J Consult Clin Psychol 68:748-66. 2000
    ....
  32. pmc Accuracy of CT colonography for detection of large adenomas and cancers
    C Daniel Johnson
    Mayo Clinic Arizona, Scottsdale, AZ, USA
    N Engl J Med 359:1207-17. 2008
    ..Computed tomographic (CT) colonography is a noninvasive option in screening for colorectal cancer. However, its accuracy as a screening tool in asymptomatic adults has not been well defined...
  33. pmc Myocardial extravascular extracellular volume fraction measurement by gadolinium cardiovascular magnetic resonance in humans: slow infusion versus bolus
    Erik B Schelbert
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Cardiovasc Magn Reson 13:16. 2011
    ..Assuming equivalence between techniques, we further hypothesized that Ve measures would be reproducible across scans...
  34. ncbi Gene expression profiling of primary cutaneous melanoma and clinical outcome
    Veronique Winnepenninckx
    Department of Pathology, Gustave Roussy Institute, 94805 Villejuif Cedex, France
    J Natl Cancer Inst 98:472-82. 2006
    ..To identify differentially expressed genes that may be involved in melanoma progression and prognosis, we investigated the relationship between gene expression profiles and clinical outcome in a cohort of patients with primary melanoma...
  35. pmc Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis
    F G R Fowkes
    JAMA 300:197-208. 2008
    ..Prediction models to identify healthy individuals at high risk of cardiovascular disease have limited accuracy. A low ankle brachial index (ABI) is an indicator of atherosclerosis and has the potential to improve prediction...
  36. ncbi Serum markers detect the presence of liver fibrosis: a cohort study
    William M C Rosenberg
    Liver Group, Division of Infection, Inflammation and Repair, University of Southampton, England SO16 6YD
    Gastroenterology 127:1704-13. 2004
    ..We developed a panel of sensitive automated immunoassays to detect matrix constituents and mediators of matrix remodeling in serum to evaluate their performance in the detection of liver fibrosis...
  37. ncbi Translating clinical research into clinical practice: impact of using prediction rules to make decisions
    Brendan M Reilly
    Cook County Stroger Hospital and Rush Medical College, Chicago, Illinois 60612, USA
    Ann Intern Med 144:201-9. 2006
    ..These considerations should inform future development, evaluation, and use of all clinical prediction or decision rules...
  38. ncbi Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model
    Xavier Forns
    Liver Unit, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Catalonia, Spain
    Hepatology 36:986-92. 2002
    ..In conclusion, a combination of easily accessible variables accurately predicts the absence of significant fibrosis and might render liver biopsy unnecessary in more than one third of patients with chronic hepatitis C...
  39. ncbi Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese
    J B Dixon
    Monash University Department of Surgery, Alfred Hospital, Melbourne 3181, Victoria, Australia
    Gastroenterology 121:91-100. 2001
    ..Predicting advanced or progressive disease may help in selecting patients for liver biopsy and assist the development of therapeutic options...
  40. doi Validation, updating and impact of clinical prediction rules: a review
    D B Toll
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    J Clin Epidemiol 61:1085-94. 2008
    ..These steps include validity assessment, updating (if necessary), and impact assessment of clinical prediction rules...
  41. ncbi Molecular classification of cancer: class discovery and class prediction by gene expression monitoring
    T R Golub
    Whitehead Institute Massachusetts Institute of Technology Center for Genome Research, Cambridge, MA 02139, USA
    Science 286:531-7. 1999
    ....
  42. ncbi Gene expression profiles and molecular markers to predict recurrence of Dukes' B colon cancer
    Yixin Wang
    Veridex, LLC, a Johnson and Johnson Company, 3210 Merryfield Row, San Diego, CA 92121, USA
    J Clin Oncol 22:1564-71. 2004
    ..In this study, we used DNA chip technology to systematically identify new prognostic markers for tumor relapse in Dukes' B patients...
  43. ncbi Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Hypertension 39:10-5. 2002
    ..This study provides the first direct evidence in a longitudinal study that aortic stiffness is an independent predictor of primary coronary events in patients with essential hypertension...
  44. doi Rapid diagnostic tests for malaria at sites of varying transmission intensity in Uganda
    Heidi Hopkins
    University of California, San Francisco, San Francisco, California, USA
    J Infect Dis 197:510-8. 2008
    ..In Africa, fever is often treated presumptively as malaria, resulting in misdiagnosis and the overuse of antimalarial drugs. Rapid diagnostic tests (RDTs) for malaria may allow improved fever management...
  45. doi Benign and malignant thyroid nodules: US differentiation--multicenter retrospective study
    Won Jin Moon
    Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    Radiology 247:762-70. 2008
    ..To retrospectively evaluate the diagnostic accuracy of ultrasonographic (US) criteria for the depiction of benign and malignant thyroid nodules by using tissue diagnosis as the reference standard...
  46. ncbi Which white blood cell subtypes predict increased cardiovascular risk?
    Benjamin D Horne
    Cardiovascular Department, LDS Hospital, Salt Lake City, Utah 84143, USA
    J Am Coll Cardiol 45:1638-43. 2005
    ..We sought to determine the predictive ability of total white blood cell (WBC) count and its subtypes for risk of death or myocardial infarction (MI)...
  47. ncbi The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD
    Paul Angulo
    Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Hepatology 45:846-54. 2007
    ..By applying this model, a liver biopsy would have been avoided in 549 (75%) of the 733 patients, with correct prediction in 496 (90%)...
  48. pmc Anti-epithelial cell adhesion molecule antibodies and the detection of circulating normal-like breast tumor cells
    Anieta M Sieuwerts
    Department of Medical Oncology, Josephine Nefkens Institute, Cancer Genomics Centre, Rotterdam, The Netherlands
    J Natl Cancer Inst 101:61-6. 2009
    ..New tests that include antibodies that specifically recognize normal-like breast tumor cells but not cells of hematopoietic origin are needed...
  49. doi Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: a 12-month follow-up
    Rossella Marcucci
    Department of Medical and Surgical Critical Care and Center for Study at Molecular and Clinical Level of Chronic, Degenerative and Neoplastic Diseases to Develop Novel Therapies, University of Florence, Florence, Italy
    Circulation 119:237-42. 2009
    ....
  50. ncbi The AD8: a brief informant interview to detect dementia
    J E Galvin
    Department of Neurology, Alzheimer Disease Research Center, Washington University, St Louis, MO 63108, USA
    Neurology 65:559-64. 2005
    ..Brief measures that accurately discriminate normal cognitive aging from very mild dementia are lacking. Cognitive tests often are insensitive to very mild dementia. Informant-based measures may be more sensitive in detecting early dementia...
  51. pmc Development of a universal dual-bolus injection scheme for the quantitative assessment of myocardial perfusion cardiovascular magnetic resonance
    Masaki Ishida
    Division of Imaging Sciences, The Rayne Institute, London, UK
    J Cardiovasc Magn Reson 13:28. 2011
    ..As a solution to one of these problems, we have devised a universal dual-bolus injection scheme for use in a clinical setting. The purpose of this study is to show the setup and feasibility of the universal dual-bolus injection scheme...
  52. pmc Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial
    Kathy S Albain
    Loyola University Chicago Stritch School of Medicine, Cardinal Bernardin Cancer Center, Maywood, IL, USA
    Lancet Oncol 11:55-65. 2010
    ....
  53. pmc Cardiovascular magnetic resonance by non contrast T1-mapping allows assessment of severity of injury in acute myocardial infarction
    Erica Dall'Armellina
    Oxford Centre for Clinical Magnetic Resonance Research, Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK
    J Cardiovasc Magn Reson 14:15. 2012
    ....
  54. ncbi Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features
    Enrico Papini
    Department of Endocrine, Metabolic and Digestive Diseases, Ospedale Regina Apostolorum, Albano, Rome, Italy
    J Clin Endocrinol Metab 87:1941-6. 2002
    ..Nonpalpable lesions of the thyroid without risk factors should be followed by means of clinical and US evaluation...
  55. pmc T1 mapping of the myocardium: intra-individual assessment of the effect of field strength, cardiac cycle and variation by myocardial region
    Nadine Kawel
    Radiology and Imaging Sciences and Molecular Biomedical Imaging Laboratory, National Institute of Biomedical Imaging and Bioengineering, Bethesda, MD, USA
    J Cardiovasc Magn Reson 14:27. 2012
    ..The purpose of this study was to evaluate acquisition factors that may result in variation of measured T1 time and ECV including magnetic field strength, cardiac phase and myocardial region...
  56. pmc T2-weighted cardiovascular magnetic resonance in acute cardiac disease
    Ingo Eitel
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    J Cardiovasc Magn Reson 13:13. 2011
    ..The principle of all things is water"Thales of Miletus (624 BC - 546 BC)...
  57. ncbi High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study
    G Walldius
    Astra Zeneca, Mölndal and King Gustaf V Research Institute, Karolinska Institute, Stockholm, Sweden
    Lancet 358:2026-33. 2001
    ..We also aimed to establish whether apoB and apoA-I add further information about risk of fatal myocardial infarction to that obtained with total cholesterol, triglycerides, and LDL-cholesterol...
  58. ncbi Body fat distribution and risk of coronary heart disease in men and women in the European Prospective Investigation Into Cancer and Nutrition in Norfolk cohort: a population-based prospective study
    Dexter Canoy
    Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK
    Circulation 116:2933-43. 2007
    ..Body fat distribution has been cross-sectionally associated with atherosclerotic disease risk factors, but the prospective relation with coronary heart disease remains uncertain...
  59. pmc Self rated health: Is it as good a predictor of subsequent mortality among adults in lower as well as in higher social classes?
    B Burstrom
    Department of Public Health Sciences, Division of Social Medicine, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    J Epidemiol Community Health 55:836-40. 2001
    ..To analyse the predictive power of self rated health for mortality in different socioeconomic groups...
  60. ncbi Gene-expression profiles predict survival of patients with lung adenocarcinoma
    David G Beer
    Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA
    Nat Med 8:816-24. 2002
    ..The identification of a set of genes that predict survival in early-stage lung adenocarcinoma allows delineation of a high-risk group that may benefit from adjuvant therapy...
  61. ncbi Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men
    David E Laaksonen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Diabetes Care 27:1036-41. 2004
    ..We assessed the association of low levels of testosterone and sex hormone-binding globulin (SHBG) with the development of the metabolic syndrome and diabetes in men...
  62. ncbi Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients
    K Kalantar-Zadeh
    Division of Nephrology and Hypertension, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California 90502, USA
    Kidney Int 70:771-80. 2006
    ....
  63. ncbi Simple cystatin C-based prediction equations for glomerular filtration rate compared with the modification of diet in renal disease prediction equation for adults and the Schwartz and the Counahan-Barratt prediction equations for children
    Anders Grubb
    Department of Clinical Chemistry, Competence Centre for Clinical Research, Department of Nephrology, University Hospital, Lund, Sweden
    Clin Chem 51:1420-31. 2005
    ..73 m(2))(-1). The present study analyzes whether these GFR prediction equations for adults and children might be replaced by simple prediction equations based on plasma concentrations of cystatin C...
  64. pmc Predictive value of brachial flow-mediated dilation for incident cardiovascular events in a population-based study: the multi-ethnic study of atherosclerosis
    Joseph Yeboah
    Department of Internal Medicine Cardiology, University of Virginia Medical Center, Charlottesville, VA 22908, USA
    Circulation 120:502-9. 2009
    ..We assessed the predictive value of FMD for incident CVD events in the Multi-Ethnic Study of Atherosclerosis (MESA)...
  65. doi Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis
    Michael Haase
    Department of Nephrology and Intensive Care Medicine, Charite University Medicine, Berlin, Germany
    Am J Kidney Dis 54:1012-24. 2009
    ..Neutrophil gelatinase-associated lipocalin (NGAL) appears to be a promising biomarker for the early diagnosis of acute kidney injury (AKI); however, a wide range in its predictive value has been reported...
  66. pmc MicroRNA targets in Drosophila
    Anton J Enright
    Computational Biology Center, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Genome Biol 5:R1. 2003
    ..Application to the D. melanogaster, Drosophila pseudoobscura and Anopheles gambiae genomes identifies several hundred target genes potentially regulated by one or more known miRNAs...
  67. pmc Use of multiple metabolic and genetic markers to improve the prediction of type 2 diabetes: the EPIC-Potsdam Study
    Matthias B Schulze
    Public Health Nutrition Unit, Technische Universitat Munchen, Freising, Germany
    Diabetes Care 32:2116-9. 2009
    ..We investigated whether metabolic biomarkers and single nucleotide polymorphisms (SNPs) improve diabetes prediction beyond age, anthropometry, and lifestyle risk factors...
  68. pmc Thirty-one novel biomarkers as predictors for clinically incident diabetes
    Veikko Salomaa
    Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland
    PLoS ONE 5:e10100. 2010
    ..However, the predictors of diabetes risk are insufficiently understood. We evaluated, whether 31 novel biomarkers could help to predict the risk of incident diabetes...
  69. pmc Baseline MRI predictors of conversion from MCI to probable AD in the ADNI cohort
    Shannon L Risacher
    IU Center for Neuroimaging, Division of Imaging Sciences, Department of Radiology, Indiana University School of Medicine, 950 W Walnut St, R2 E124, Indianapolis, IN 46202, USA
    Curr Alzheimer Res 6:347-61. 2009
    ..Validation of imaging biomarkers is important as they can help enrich clinical trials of disease modifying agents by identifying individuals at highest risk for progression to AD...
  70. pmc Semi-automatic quantification of 4D left ventricular blood flow
    Jonatan Eriksson
    Division of Cardiovascular Medicine, Department of Medical and Health Sciences, Linkoping University, Linkoping, Sweden
    J Cardiovasc Magn Reson 12:9. 2010
    ..Methods for the quantification of intra-cardiac blood flow, with its 4D (3D+time) nature, are lacking. We sought to develop and validate a novel semi-automatic analysis approach that integrates flow and morphological data...
  71. doi Negative and positive predictive value of a whole-blood interferon-γ release assay for developing active tuberculosis: an update
    Roland Diel
    Department of Pneumology, Medical School Hannover MHH, Carl Neuberg Str 1, 30625 Hannover, Germany
    Am J Respir Crit Care Med 183:88-95. 2011
    ..only limited data are available on the predictive value of interferon-γ release assays for progression from latent tuberculosis infection to active tuberculosis (TB)...
  72. pmc Cardiac T2* magnetic resonance for prediction of cardiac complications in thalassemia major
    P Kirk
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney St, London SW3 6NP, UK
    Circulation 120:1961-8. 2009
    ..The goal of this study was to determine the predictive value of cardiac T2* magnetic resonance for heart failure and arrhythmia in thalassemia major...
  73. pmc Operational accuracy and comparative persistent antigenicity of HRP2 rapid diagnostic tests for Plasmodium falciparum malaria in a hyperendemic region of Uganda
    Daniel J Kyabayinze
    Malaria Consortium Africa, Plot 2, Sturrock Road, P O Box 8045, Kampala, Uganda
    Malar J 7:221. 2008
    ..An assessment of the accuracy of Malaria Pf immuno-chromatographic test (ICT) and description of persistent antigenicity of HRP2 RDTs was undertaken in a hyperendemic area of Uganda...
  74. pmc T2 quantification for improved detection of myocardial edema
    Shivraman Giri
    Department of Biomedical Engineering, The Ohio State University, Columbus, Ohio, USA
    J Cardiovasc Magn Reson 11:56. 2009
    ..In this work we demonstrate the advantages of a quantitative T2 mapping technique to accurately and reliably detect regions of edematous myocardial tissue without the limitations of qualitative T2W imaging...
  75. pmc Predicting diabetes: clinical, biological, and genetic approaches: data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR)
    Beverley Balkau
    INSERM U780 IFR69, Villejuif, France University Paris Sud, Orsay, France
    Diabetes Care 31:2056-61. 2008
    ..To provide a simple clinical diabetes risk score and to identify characteristics that predict later diabetes using variables available in the clinic setting as well as biological variables and polymorphisms...
  76. doi Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coro
    Matthew J Budoff
    Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, California, USA
    J Am Coll Cardiol 52:1724-32. 2008
    ..The purpose of this study was to evaluate the diagnostic accuracy of electrocardiographically gated 64-multidetector row coronary computed tomographic angiography (CCTA) in individuals without known coronary artery disease (CAD)...
  77. ncbi Prediction of esophageal varices in patients with cirrhosis
    Ravi Madhotra
    Liver Service, Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Clin Gastroenterol 34:81-5. 2002
    ..To identify predictors of esophageal varices (EV) using available clinical, laboratory, and diagnostic imaging variables...
  78. ncbi Comparison and validation of simple noninvasive tests for prediction of fibrosis in chronic hepatitis C
    Carolin Lackner
    Department of Pathology, Medical University Graz, Graz, Austria
    Hepatology 41:1376-82. 2005
    ..In conclusion, simple fibrosis tests may render liver biopsy unnecessary only in a minority of patients with chronic HCV. Improved serum fibrosis markers with greater sensitivity for severe fibrosis or cirrhosis are needed...
  79. doi Cell-type specific gene expression signature in liver underlies response to interferon therapy in chronic hepatitis C infection
    Limin Chen
    Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada
    Gastroenterology 138:1123-33.e1-3. 2010
    ..We here study how the nonresponder gene expression phenotype is influenced by clinical factors and uncover the cellular basis of the phenotype through ISG15 protein expression...
  80. ncbi Identifying patients at risk for significant versus clinically insignificant postoperative prostate-specific antigen failure
    Anthony V D'Amico
    Brigham and Women s Hospital, Department of Radiation Oncology, Dana Faber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 23:4975-9. 2005
    ..We evaluated whether men at risk for significant versus clinically insignificant prostate-specific antigen (PSA) failure after radical prostatectomy could be identified using information available at diagnosis...
  81. ncbi FibroIndex, a practical index for predicting significant fibrosis in patients with chronic hepatitis C
    Masahiko Koda
    Second Department of Internal Medicine, Faculty of Medicine, Tottori University, Yonago, Tottori, Japan
    Hepatology 45:297-306. 2007
    ..Conclusion: The FibroIndex is a simple and reliable index for predicting significant fibrosis in chronic hepatitis C and could also be used as a surrogate marker during antifibrotic treatment for chronic hepatitis C...
  82. doi Myocardial salvage by CMR correlates with LV remodeling and early ST-segment resolution in acute myocardial infarction
    Pier Giorgio Masci
    MRI Unit, G Monasterio Foundation CNR Regione Toscana, Pisa, Italy
    JACC Cardiovasc Imaging 3:45-51. 2010
    ..The purpose of this study was to assess the association of myocardial salvage by cardiac magnetic resonance (CMR) with left ventricular (LV) remodeling and early ST-segment resolution in patients with acute myocardial infarction (MI)...
  83. ncbi Detecting acute coronary syndrome in the emergency department with cardiac magnetic resonance imaging
    Raymond Y Kwong
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    Circulation 107:531-7. 2003
    ..Managing chest pain in the emergency department remains a challenge with current diagnostic strategies. We hypothesized that cardiac MRI could accurately identify patients with possible or probable acute coronary syndrome...
  84. doi Magnetic resonance-derived 3-dimensional blood flow patterns in the main pulmonary artery as a marker of pulmonary hypertension and a measure of elevated mean pulmonary arterial pressure
    Gert Reiter
    Siemens Medical Solutions, Graz, Austria
    Circ Cardiovasc Imaging 1:23-30. 2008
    ..Such pathological altered pressures in the pulmonary vascular system should lead to changes in blood flow patterns in the main pulmonary artery...
  85. ncbi The electrocardiogram predicts one-year outcome of patients with unstable angina and non-Q wave myocardial infarction: results of the TIMI III Registry ECG Ancillary Study. Thrombolysis in Myocardial Ischemia
    C P Cannon
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 30:133-40. 1997
    ..We sought to determine the prognostic value of the admission electrocardiogram (ECG) in patients with unstable angina and non-Q wave myocardial infarction (MI)...
  86. ncbi Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease
    P D Mehta
    Department of Immunology, New York State Institute for Basic Research in Developmental Disabilities, Staten Island 10314, USA
    Arch Neurol 57:100-5. 2000
    ..However, no information is published on plasma Abeta40 and Abeta42 levels in relation to Apo E genotype or severity of dementia in sporadic AD...
  87. ncbi Procalcitonin and C-reactive protein as diagnostic markers of severe bacterial infections in febrile infants and children in the emergency department
    Barbara Andreola
    Department of Pediatrics, University of Padova, Italy
    Pediatr Infect Dis J 26:672-7. 2007
    ....
  88. doi Prospective comparison of severity scores for predicting clinically relevant outcomes for patients hospitalized with community-acquired pneumonia
    Pedro Pablo España Yandiola
    Service of Pneumology, Hospital Galdakao Usansolo, Barrio Labeaga s n 48960 Galdakao, Bizkaia, Spain
    Chest 135:1572-9. 2009
    ..The comparative accuracy and discriminatory power of three validated rules for predicting clinically relevant outcomes other than mortality in patients hospitalized with community-acquired pneumonia (CAP) are unknown...
  89. pmc The absence of coronary calcification does not exclude obstructive coronary artery disease or the need for revascularization in patients referred for conventional coronary angiography
    Ilan Gottlieb
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Am Coll Cardiol 55:627-34. 2010
    ..This study was designed to evaluate whether the absence of coronary calcium could rule out >or=50% coronary stenosis or the need for revascularization...
  90. ncbi Delayed enhancement magnetic resonance imaging predicts response to cardiac resynchronization therapy in patients with intraventricular dyssynchrony
    James A White
    Division of Cardiology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    J Am Coll Cardiol 48:1953-60. 2006
    ..We evaluated the ability of delayed enhancement magnetic resonance imaging (DE-MRI) to predict clinical response to cardiac resynchronization therapy (CRT)...
  91. ncbi Development of a nomogram to predict probability of positive initial prostate biopsy among Japanese patients
    Hiroyoshi Suzuki
    Department of Urology, Chiba University Graduate School of Medicine, Chiba, Japan
    Urology 67:131-6. 2006
    ..We, therefore, developed a model for predicting the probability of a positive initial prostate biopsy using clinical and laboratory data from a Japanese male population...
  92. doi Comparison of magnetic resonance feature tracking for strain calculation with harmonic phase imaging analysis
    Kan N Hor
    Department of Cardiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    JACC Cardiovasc Imaging 3:144-51. 2010
    ....
  93. ncbi Predicting response of colorectal hepatic metastasis: value of pretreatment apparent diffusion coefficients
    Dow Mu Koh
    Academic Department of Radiology, Royal Marsden Hospital, Downs Rd, Sutton, Surrey, United Kingdom, SM2 5PT
    AJR Am J Roentgenol 188:1001-8. 2007
    ....
  94. ncbi Dosage adjustment and pharmacokinetic profile of irinotecan in cancer patients with hepatic dysfunction
    Eric Raymond
    Department of Medicine, Gustave Roussy Institute, Villejuif, France
    J Clin Oncol 20:4303-12. 2002
    ..To determine the recommended dose (RD) and the pharmacokinetic profile of irinotecan and its metabolites in cancer patients with hyperbilirubinemia...
  95. ncbi Acceptance of chronic pain: component analysis and a revised assessment method
    Lance M McCracken
    Pain Management Unit, Royal National Hospital for Rheumatic Diseases and University of Bath, Bath BA1 1RL, UK
    Pain 107:159-66. 2004
    ..A revised version of the CPAQ is suggested...
  96. doi Real-time endobronchial ultrasound-guided transbronchial needle aspiration in mediastinal staging of non-small cell lung cancer: how many aspirations per target lymph node station?
    Hee Seok Lee
    Center for Lung Cancer, National Cancer Center, 809 Madu dong, Ilsan gu, Goyang, Gyeonggi, 411 764, Korea
    Chest 134:368-74. 2008
    ....
  97. ncbi Ultrasonic echolucent carotid plaques predict future strokes
    M L Grønholdt
    Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Osaka, Japan
    Circulation 104:68-73. 2001
    ..We tested prospectively the hypothesis that stroke development can be predicted by echolucency of carotid atherosclerotic plaques in previously symptomatic and asymptomatic patients...
  98. ncbi Use of soluble fibrin antigen instead of D-dimer as fibrin-related marker may enhance the prognostic power of the ISTH overt DIC score
    Carl Erik Dempfle
    University Hospital of Mannheim, I Department of Medicine, Theodor Kutzer Ufer 1 3, D 68167 Mannheim, Germany
    Thromb Haemost 91:812-8. 2004
    ..The present data on the distribution of values may provide a basis for the selection of appropriate cutoff points for assigning 2, and 3 points in the score...
  99. doi Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE)
    J Vestbo
    Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark
    Eur Respir J 31:869-73. 2008
    ....
  100. doi Multi-modal imaging predicts memory performance in normal aging and cognitive decline
    K B Walhovd
    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Norway
    Neurobiol Aging 31:1107-21. 2010
    ..Medial temporal and parietal metabolism and morphometry best explained memory variance. Medial temporal characteristics were related to learning, recall and recognition, while parietal structures only predicted learning...
  101. doi Clinical significance of radiologic characterizations in COPD
    MeiLan K Han
    University of Michigan Health System, Ann Arbor, Michigan 48109 5360, USA
    COPD 6:459-67. 2009
    ..Future research should clarify whether CT parameters complement BODE score in influencing survival...

Research Grants301 found, 100 shown here

  1. Rapid Test for Monitoring Dust Mite Avoidance in Homes
    Martin Chapman; Fiscal Year: 2004
    ..The predictive value of tests for mite Group 1 and Group 2 allergens will be compared to select the optimal test for allergen ..
  2. Development of Improved Earphone for Hearing Testing
    Robert Margolis; Fiscal Year: 2007
    ..In this project an earphone is being developed that can be used in both automated and manual testing and will significantly increase the efficiency, accuracy, and accessibility. ..
  3. Hypertension in Hemodialysis Patients
    Rajiv Agarwal; Fiscal Year: 2010
    ..We hypothesize that that volume control can improve BP and antihypertensive therapy can regress left ventricular hypertrophy in long-term hemodialysis patients. ..
  4. Long-term Outcomes of Cochlear Implantation in Early Childhood
    Ann Geers; Fiscal Year: 2009
    ..In addition we will document the incidence and outcomes associated with discontinued use of a cochlear implant. ..
  5. Reducing Risk Factors in Peripheral Arterial Disease
    Mary McDermott; Fiscal Year: 2007
    ....
  6. Novel Treatment Strategies for Constipation and Role of Brain-Gut axis
    Satish Rao; Fiscal Year: 2007
    ..These studies aim to define the mechanisms of, and evaluate new therapies for dyssynergia, rectal hyposensitivity and rectal hypersensitivity, and could significantly impact constipation treatments. ..
  7. BLOOD FACTORS AND PERIPHERAL ARTERIAL DISEASE OUTCOMES
    Mary McDermott; Fiscal Year: 2004
    ....
  8. DRUG USE AND PROBLEM BEHAVIORS IN MINORITY YOUTH
    Judith Brook; Fiscal Year: 2001
    ....
  9. PERIPHERAL ARTERIAL DISEASE AND FUNCTIONAL OUTCOMES
    Mary McDermott; Fiscal Year: 2001
    ..They further state that the results of this study will be used to develop subsequent intervention studies designed to improve quality of life and prevent functional decline among men and women with PAD. ..
  10. Vascular Medicine at Northwestern University
    Mary McDermott; Fiscal Year: 2007
    ..End of Abstract) ..
  11. Inflammation and Peripheral Arterial Disease Outcomes
    Mary McDermott; Fiscal Year: 2007
    ..Results will be used to develop interventions to improve functioning and prevent functional decline in PAD. ..
  12. DRUG USE AND PROBLEM BEHAVIORS IN MINORITY YOUTH
    Judith Brook; Fiscal Year: 2007
    ..abstract_text> ..
  13. Novel Treatment Strategies for Constipation and Role of Brain-Gut axis
    SATISH SC RAO; Fiscal Year: 2010
    ..These studies aim to define the mechanisms of, and evaluate new therapies for dyssynergia, rectal hyposensitivity and rectal hypersensitivity, and could significantly impact constipation treatments. ..
  14. Vitamin D Levels and Peripheral Arterial Disease Outcomes
    Mary Mcgrae McDermott; Fiscal Year: 2010
    ..The current study will establish whether low baseline vitamin D levels are associated with greater functional limitation and faster functional decline compared to higher vitamin D levels in persons with PAD. ..
  15. Reducing Risk Factors in Peripheral Arterial Disease
    Mary Mcgrae McDermott; Fiscal Year: 2010
    ....
  16. Blood Markers of Vulnerability in High Risk Vascular Patients
    Mary Mcgrae McDermott; Fiscal Year: 2010
    ..Findings may help clinicians identify patients who are at particularly high-risk for an impending heart attack. Results are also expected to elucidate specific triggers of acute coronary events. ..
  17. TOBACCO USE AMONG MINORITY YOUTH: A LONGITUDINAL STUDY
    Judith Brook; Fiscal Year: 2006
    ....
  18. Pathobiology of Kidney Disease: Role of Iron
    Rajiv Agarwal; Fiscal Year: 2007
    ..Novelty and Health Relatedness of the Project: This proposal will provide translational data on the role of intravenous iron to progression of kidney disease in patients with CKD. ..
  19. Novel Treatment Strategies for Constipation and Role of Brain-Gut axis
    Satish Rao; Fiscal Year: 2009
    ..These studies aim to define the mechanisms of, and evaluate new therapies for dyssynergia, rectal hyposensitivity and rectal hypersensitivity, and could significantly impact constipation treatments. ..
  20. TOBACCO USE AMONG MINORITY YOUTH: A LONGITUDINAL STUDY
    Judith Brook; Fiscal Year: 2009
    ..Findings will help physicians, educators, and policy makers provide healthy environments. ..
  21. A Longitudinal Study of the Predictors of Smoking in Women in Late Midlife
    Judith Brook; Fiscal Year: 2009
    ....
  22. Novel Biomarkers in Cardiac Surgery to Detect Acute Kidney Injury
    Chirag R Parikh; Fiscal Year: 2010
    ..The ultimate findings of this study will pave the way for larger multi-center studies of these biomarkers in other clinical conditions and for interventional clinical trials to prevent or to treat AKI. ..
  23. Childhood Determinants of Adolescent / Adult Drug Use
    Judith S Brook; Fiscal Year: 2010
    ..Identification of childhood and adolescent factors that can exacerbate the impact of substance use consequences on later adult functioning would provide additional information necessary for effective treatment efforts. ..
  24. Hypertension in Hemodialysis Patients
    Rajiv Agarwal; Fiscal Year: 2007
    ..Evaluation of such strategies will improve BP control in hemodialysis patients and, in the long-term, provide cardiovascular protection. ..
  25. Novel Biomarkers in Cardiac Surgery to Detect Acute Kidney Injury
    Chirag Parikh; Fiscal Year: 2009
    ..The ultimate findings of this study will pave the way for larger multi-center studies of these biomarkers in other clinical conditions and for interventional clinical trials to prevent or to treat AKI. ..
  26. Aortic Calcium: epidemiology and progression
    Michael Criqui; Fiscal Year: 2006
    ..abstract_text> ..
  27. UCSD Integrated Cardiovascular Epidemiology Fellowship
    Michael Criqui; Fiscal Year: 2007
    ..Due to the expertise, experience and breadth of mentors committed to the program, rich opportunities exist for exceptional research experiences incorporating an interdisciplinary approach. ..
  28. The Incidence and Progression of Peripheral Venous Disease
    Michael Criqui; Fiscal Year: 2007
    ..This application builds on the seminal findings in our prevalence study, and since no such incidence data exist, is original and innovative. ..
  29. Predicting dementia with practice effects
    Kevin Duff; Fiscal Year: 2009
    ..Finally, the availability of a brief, non-invasive, and cost effective marker of disease progression would allow for more efficient and better powered clinical trials. ..
  30. The Incidence and Progression of Peripheral Venous Disease
    Michael H Criqui; Fiscal Year: 2010
    ..This application builds on the seminal findings in our prevalence study, and since no such incidence data exist, is original and innovative. ..
  31. Ethnic differences in peripheral arterial disease
    Michael Criqui; Fiscal Year: 2004
    ..This is the first attempt to see if these newer risk markers can explain ethnic differences in PAD. Thus, this application is highly innovative and addresses original hypotheses. ..
  32. The Incidence and Progression of Peripheral Venous Disease
    Michael Criqui; Fiscal Year: 2009
    ..This application builds on the seminal findings in our prevalence study, and since no such incidence data exist, is original and innovative. ..
  33. A Novel Breast Cancer Biomarker
    Dennis C Sgroi; Fiscal Year: 2010
    ....
  34. Biological Factors for Age-Related Macular Degeneration
    Johanna Seddon; Fiscal Year: 2004
    ..abstract_text> ..
  35. Stroke Recovery in Underserved Populations
    Glenn Ostir; Fiscal Year: 2007
    ..The work is also important as it has the potential to "contribute important insights into why some do well and others do poorly in the face of persistent challenges." ..
  36. Personalized Response Indicators of SSRI Effectiveness in Major Depression
    Ian A Cook; Fiscal Year: 2010
    ....
  37. Psychological Well Being and Recovery Among Older Hospitalized Adults
    Glenn V Ostir; Fiscal Year: 2010
    ..A central goal of the current application is to examine whether psychological well-being can influence the risk for functional status decline associated with hospitalization in an ethnically diverse older patient population. ..
  38. INNOVATIVE JOB PLACEMENT MODEL FOR METHADONE PATIENTS
    Stephen Magura; Fiscal Year: 2004
    ..4) To conduct benefit-cost and cost-effectiveness analyses of the modified IPS vocational rehabilitation program. ..
  39. Ventricular Size and Valve Calcification Measures by CT
    Matthew J Budoff; Fiscal Year: 2010
    ..abstract_text> ..
  40. "Naturalistic Assessment of the Driving ability of Cognitively Impaired Elders
    Brian Ott; Fiscal Year: 2007
    ....