discriminant analysis

Summary

Summary: A statistical analytic technique used with discrete dependent variables, concerned with separating sets of observed values and allocating new values. It is sometimes used instead of regression analysis.

Top Publications

  1. pmc Differentiating prenatal exposure to methamphetamine and alcohol versus alcohol and not methamphetamine using tensor-based brain morphometry and discriminant analysis
    Elizabeth R Sowell
    Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, Los Angeles, California 90095, USA
    J Neurosci 30:3876-85. 2010
  2. pmc Discriminant analysis of principal components: a new method for the analysis of genetically structured populations
    Thibaut Jombart
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College Faculty of Medicine, St Mary s Campus, Norfolk Place, London W21PG, UK
    BMC Genet 11:94. 2010
  3. pmc Selection bias in gene extraction on the basis of microarray gene-expression data
    Christophe Ambroise
    Laboratoire Heudiasyc, Unité Mixte de Recherche Centre National de la Recherche Scientifique 6599, 60200 Compiegne, France
    Proc Natl Acad Sci U S A 99:6562-6. 2002
  4. ncbi Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index
    Milo A Puhan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet 374:704-11. 2009
  5. ncbi Metabolic profiling of plasma in overweight/obese and lean men using ultra performance liquid chromatography and Q-TOF mass spectrometry (UPLC-Q-TOF MS)
    Ji Young Kim
    Yonsei University Research Institute of Science for Aging, Laboratory of Clinical Nutrigenetics Nutrigenomics, Department of Food and Nutrition, Brain Korea 21 Project, College of Human Ecology, Yonsei University, Seoul, Korea
    J Proteome Res 9:4368-75. 2010
  6. pmc Diagnosis of multiple cancer types by shrunken centroids of gene expression
    Robert Tibshirani
    Department of Health, Research and Policy, and Statistics, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 99:6567-72. 2002
  7. ncbi General tensor discriminant analysis and gabor features for gait recognition
    Dacheng Tao
    Department of Computing, Hong Kong Polytechnic University, Kowloon
    IEEE Trans Pattern Anal Mach Intell 29:1700-15. 2007
  8. pmc Baseline prediction of combination therapy outcome in hepatitis C virus 1b infected patients by discriminant analysis using viral and host factors
    Verónica Saludes
    Microbiology Service, Fundació Institut d Investigació en Ciències de la Salut Germans Trias i Pujol, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
    PLoS ONE 5:e14132. 2010
  9. ncbi Discriminative analysis of resting-state functional connectivity patterns of schizophrenia using low dimensional embedding of fMRI
    Hui Shen
    College of Mechatronics and Automation, National University of Defense Technology, Changsha, Hunan 410073, China
    Neuroimage 49:3110-21. 2010
  10. ncbi Sexing skulls using discriminant function analysis of visually assessed traits
    Phillip L Walker
    Department of Anthropology, University of California, Santa Barbara, California 93106, USA
    Am J Phys Anthropol 136:39-50. 2008

Detail Information

Publications311 found, 100 shown here

  1. pmc Differentiating prenatal exposure to methamphetamine and alcohol versus alcohol and not methamphetamine using tensor-based brain morphometry and discriminant analysis
    Elizabeth R Sowell
    Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, Los Angeles, California 90095, USA
    J Neurosci 30:3876-85. 2010
    ....
  2. pmc Discriminant analysis of principal components: a new method for the analysis of genetically structured populations
    Thibaut Jombart
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College Faculty of Medicine, St Mary s Campus, Norfolk Place, London W21PG, UK
    BMC Genet 11:94. 2010
    ..Unfortunately, currently available multivariate methods still lack some essential features needed to study the genetic structure of natural populations...
  3. pmc Selection bias in gene extraction on the basis of microarray gene-expression data
    Christophe Ambroise
    Laboratoire Heudiasyc, Unité Mixte de Recherche Centre National de la Recherche Scientifique 6599, 60200 Compiegne, France
    Proc Natl Acad Sci U S A 99:6562-6. 2002
    ..Using two published data sets, we demonstrate that when correction is made for the selection bias, the cross-validated error is no longer zero for a subset of only a few genes...
  4. ncbi Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index
    Milo A Puhan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet 374:704-11. 2009
    ..We assessed the calibration of the BODE index, updated it to improve its calibration, and developed and validated a simplified index for use in primary-care settings...
  5. ncbi Metabolic profiling of plasma in overweight/obese and lean men using ultra performance liquid chromatography and Q-TOF mass spectrometry (UPLC-Q-TOF MS)
    Ji Young Kim
    Yonsei University Research Institute of Science for Aging, Laboratory of Clinical Nutrigenetics Nutrigenomics, Department of Food and Nutrition, Brain Korea 21 Project, College of Human Ecology, Yonsei University, Seoul, Korea
    J Proteome Res 9:4368-75. 2010
    ..Additionally, the amount of dietary saturated fat may influence the proportion of saturated fatty acids in serum phospholipids and the degree of saturation of the constituent acyl group of plasma lysoPC...
  6. pmc Diagnosis of multiple cancer types by shrunken centroids of gene expression
    Robert Tibshirani
    Department of Health, Research and Policy, and Statistics, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 99:6567-72. 2002
    ..The technique is general and can be used in many other classification problems. To demonstrate its effectiveness, we show that the method was highly efficient in finding genes for classifying small round blue cell tumors and leukemias...
  7. ncbi General tensor discriminant analysis and gabor features for gait recognition
    Dacheng Tao
    Department of Computing, Hong Kong Polytechnic University, Kowloon
    IEEE Trans Pattern Anal Mach Intell 29:1700-15. 2007
    ..image representations are not suited to conventional classification methods, such as the linear discriminant analysis (LDA), because of the under sample problem (USP): the dimensionality of the feature space is much higher ..
  8. pmc Baseline prediction of combination therapy outcome in hepatitis C virus 1b infected patients by discriminant analysis using viral and host factors
    Verónica Saludes
    Microbiology Service, Fundació Institut d Investigació en Ciències de la Salut Germans Trias i Pujol, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
    PLoS ONE 5:e14132. 2010
    ..We aimed to identify pre-treatment clinical and virological parameters associated with treatment failure, as well as to assess whether therapy outcome could be predicted at baseline...
  9. ncbi Discriminative analysis of resting-state functional connectivity patterns of schizophrenia using low dimensional embedding of fMRI
    Hui Shen
    College of Mechatronics and Automation, National University of Defense Technology, Changsha, Hunan 410073, China
    Neuroimage 49:3110-21. 2010
    ....
  10. ncbi Sexing skulls using discriminant function analysis of visually assessed traits
    Phillip L Walker
    Department of Anthropology, University of California, Santa Barbara, California 93106, USA
    Am J Phys Anthropol 136:39-50. 2008
    ..Linear, kth-nearest-neighbor, logistic, and quadratic discriminant analysis models were evaluated based on their capacity to minimize both misclassifications and sex biases in ..
  11. ncbi Comparing the standard EQ-5D three-level system with a five-level version
    Mathieu F Janssen
    Public Health Epidemiology, Academic Medical Center, Amsterdam, The Netherlands
    Value Health 11:275-84. 2008
    ..The aim of this study is a head-to-head comparison of the performance of the three-level EQ-5D (3L) and a newly developed five-level version (5L)...
  12. pmc Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems
    Kim Anh Lê Cao
    Queensland Facility for Advanced Bioinformatics, University of Queensland, 4072 St Lucia, QLD, Australia
    BMC Bioinformatics 12:253. 2011
    ..In the case of multiple highly correlated variables, another option is to use multivariate exploratory approaches to give more insight into cell biology, biological pathways or complex traits...
  13. pmc Variable selection for discriminant analysis with Markov random field priors for the analysis of microarray data
    Francesco C Stingo
    Department of Statistics, Rice University, Houston, TX 77005, USA
    Bioinformatics 27:495-501. 2011
    b>Discriminant analysis is an effective tool for the classification of experimental units into groups...
  14. ncbi Fusion of fuzzy statistical distributions for classification of thyroid ultrasound patterns
    Dimitris K Iakovidis
    Department of Informatics and Computer Technology, Technological Educational Institute of Lamia, Lamia, Greece
    Artif Intell Med 50:33-41. 2010
    ..This representation is suitable for the discrimination of nodules of high malignancy risk from normal thyroid parenchyma...
  15. ncbi KPCA plus LDA: a complete kernel Fisher discriminant framework for feature extraction and recognition
    Jian Yang
    Department of Computer Science, Nanjing University of Science and Technology, Nanjing 210094, PR China
    IEEE Trans Pattern Anal Mach Intell 27:230-44. 2005
    This paper examines the theory of kernel Fisher discriminant analysis (KFD) in a Hilbert space and develops a two-phase KFD framework, i.e., kernel principal component analysis (KPCA) plus Fisher linear discriminant analysis (LDA)...
  16. pmc Characterization of metabolic differences between benign and malignant tumors: high-spectral-resolution diffuse optical spectroscopy
    Shwayta Kukreti
    Beckman Laser Institute, University of California, Irvine, CA 92612, USA
    Radiology 254:277-84. 2010
    ..To develop a near-infrared spectroscopic method to identify breast cancer biomarkers and to retrospectively determine if benign and malignant breast lesions could be distinguished by using this method...
  17. pmc Facial expression recognition based on local binary patterns and kernel discriminant isomap
    Xiaoming Zhao
    Department of Computer Science, Taizhou University, Taizhou 317000, China
    Sensors (Basel) 11:9573-88. 2011
    ..KDIsomap outperforms the other used methods such as principal component analysis (PCA), linear discriminant analysis (LDA), kernel principal component analysis (KPCA), kernel linear discriminant analysis (KLDA) as well as ..
  18. ncbi Identification of new antimalarial drugs by linear discriminant analysis and topological virtual screening
    Nassira Mahmoudi
    INSERM U511, Immuno Biologie Cellulaire et Moleculaire des Infections Parasitaires, CHU Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    J Antimicrob Chemother 57:489-97. 2006
    ....
  19. ncbi Study of on-line adaptive discriminant analysis for EEG-based brain computer interfaces
    C Vidaurre
    Department of Electrical and Electronic Engineering, Public University of Navarre, Campus Arrosadia s n, 31006 Pamplona, Spain
    IEEE Trans Biomed Eng 54:550-6. 2007
    ..Two continuously adaptive classifiers were tested: adaptive quadratic and linear discriminant analysis. Three feature types were analyzed, adaptive autoregressive parameters, logarithmic band power estimates ..
  20. ncbi Toward unsupervised adaptation of LDA for brain-computer interfaces
    C Vidaurre
    Department ofMachine Learning, Berlin Institute of Technology, 10623 Berlin, Germany
    IEEE Trans Biomed Eng 58:587-97. 2011
    ..In this paper, we suggest a simple unsupervised adaptation method of the linear discriminant analysis (LDA) classifier that effectively solves this problem by counteracting the harmful effect of nonclass-..
  21. ncbi Multiple binary classifications via linear discriminant analysis for improved controllability of a powered prosthesis
    Levi J Hargrove
    Institute of Biomedical Engineering, University of New Brunswick, Fredericton, NB E3B5A3, Canada
    IEEE Trans Neural Syst Rehabil Eng 18:49-57. 2010
    ..case, the proposed system was compared to a state-of-the-art pattern recognition system based on linear discriminant analysis and a conventional myoelectric control scheme with mode switching...
  22. pmc Sparse linear discriminant analysis for simultaneous testing for the significance of a gene set/pathway and gene selection
    Michael C Wu
    Department of Biostatistics, Harvard School of Public Health, 655 Huntington Ave, Boston, MA 02115, USA
    Bioinformatics 25:1145-51. 2009
    ..For a significantly differentially expressed pathway, it is also of substantial interest to select important genes that drive the differential expression of the pathway...
  23. ncbi Globally maximizing, locally minimizing: unsupervised discriminant projection with applications to face and palm biometrics
    Jian Yang
    Department of Computing, Hong Kong Polytechnic University, Kowloon, Hong Kong
    IEEE Trans Pattern Anal Mach Intell 29:650-64. 2007
    ..The experimental results show that UDP consistently outperforms LPP and PCA and outperforms LDA when the training sample size per class is small. This demonstrates that UDP is a good choice for real-world biometrics applications...
  24. ncbi Nanoarray of polycyclic aromatic hydrocarbons and carbon nanotubes for accurate and predictive detection in real-world environmental humidity
    Yael Zilberman
    The Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion Israel Institute of Technology, Haifa 32000, Israel
    ACS Nano 5:6743-53. 2011
    ..The results presented here could lead to the development of a cost-effective, lightweight, low-power, and non-invasive tool for a widespread detection of VOCs in real-world environmental, security, food, health, and other applications...
  25. ncbi Metabolic dynamics during autumn cold acclimation within and among populations of Sitka spruce (Picea sitchensis)
    Rebecca Dauwe
    Department of Wood Science, Faculty of Forestry, The University of British Columbia, 2424 Main Mall, Vancouver, BC V6T 1Z4, Canada
    New Phytol 194:192-205. 2012
    ....
  26. ncbi Automated differentiation of pre-diagnosis Huntington's disease from healthy control individuals based on quadratic discriminant analysis of the basal ganglia: the IMAGE-HD study
    N Georgiou-Karistianis
    School of Psychology and Psychiatry, Faculty of Medicine Nursing and Health Sciences, Monash University, Clayton, VIC 3800, Australia
    Neurobiol Dis 51:82-92. 2013
    ..We applied quadratic discriminant analysis (QDA) to discriminate pre-HD individuals from controls and we utilised feature selection and dimension ..
  27. ncbi Discrimination of functional hepatocytes derived from mesenchymal stem cells using FTIR microspectroscopy
    Danna Ye
    Embryo Technology and Stem Cell Research Center, School of Biotechnology, Suranaree University of Technology, Nakhon Ratchasima, Thailand
    Analyst 137:4774-84. 2012
    ..Partial Least Squares Discriminant Analysis (PLS-DA) enabled us to discriminate undifferentiated rBM-MSCs, and early, mid-stage and late stage rBM-..
  28. ncbi Sex determination by discriminant function analysis of the tibia for contemporary Croats
    Mario Slaus
    Department of Archaeology, Croatian Academy of Sciences and Arts, Ante Kovacica 5, 10 000 Zagreb, Croatia
    Forensic Sci Int 226:302.e1-4. 2013
    ..Standardized coefficients of the discriminant functions generated in this study support the results of previous studies that found that breadth dimensions provide better separation of the sexes than length...
  29. ncbi Discriminant analysis of functional connectivity patterns on Grassmann manifold
    Yong Fan
    LIAMA Center for Computational Medicine, National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China
    Neuroimage 56:2058-67. 2011
    ..each network encoded by a spatial independent component separately, we propose a novel algorithm for discriminant analysis of functional brain networks jointly at an individual level...
  30. ncbi Orthogonal projections to latent structures discriminant analysis modeling on in situ FT-IR spectral imaging of liver tissue for identifying sources of variability
    Hans Stenlund
    Computational Life Science Cluster CLIC, KBC, Umea University, SE 901 87 Umea, Sweden
    Anal Chem 80:6898-906. 2008
    In this study, the orthogonal projections to latent structures discriminant analysis (OPLS-DA) method was used to assess the in situ chemical composition of two different cell types in mouse liver samples, hepatocytes and erythrocytes...
  31. ncbi Comparison of linear, nonlinear, and feature selection methods for EEG signal classification
    Deon Garrett
    Department of Computer Science, Colorado State University, Fort Collins 80523, USA
    IEEE Trans Neural Syst Rehabil Eng 11:141-4. 2003
    ..This paper reports the results of a linear (linear discriminant analysis) and two nonlinear classifiers (neural networks and support vector machines) applied to the classification ..
  32. ncbi Fourier transform infrared (FT-IR) spectroscopy in bacteriology: towards a reference method for bacteria discrimination
    Ornella Preisner
    Centre for Biological and Chemical Engineering, IST, Technical University of Lisbon, Av Rovisco Pais, 1049 001 Lisbon, Portugal
    Anal Bioanal Chem 387:1739-48. 2007
    ..The uncertainty in estimating scores was reduced by about 50% when compared to models with all wavelengths. Spectral ranges with relevant chemical information for Enterococcus faecium bacteria discrimination were outlined...
  33. ncbi Multilinear discriminant analysis for face recognition
    Shuicheng Yan
    Microsoft Research Asia, Beijing 100080, China
    IEEE Trans Image Process 16:212-20. 2007
    ..We call this algorithm multilinear discriminant analysis (MDA), which has the following characteristics: 1) multiple interrelated subspaces can collaborate to ..
  34. ncbi Tensor discriminant color space for face recognition
    Su Jing Wang
    College of Computer Science and Technology, Jilin University, Changchun 130012, China
    IEEE Trans Image Process 20:2490-501. 2011
    ....
  35. ncbi Correspondence discriminant analysis: a multivariate method for comparing classes of protein and nucleic acid sequences
    G Perrière
    Laboratoire de Biometrie, Génétique et Biologie des Populations, UMR CNRS n 5558, Universite Claude Bernard, Lyon, Villeurbanne, France
    Comput Appl Biosci 12:519-24. 1996
    ..of a multivariate method for studying classes of nucleotide or protein sequences: correspondence discriminant analysis (CDA)...
  36. pmc An HR-MAS MR metabolomics study on breast tissues obtained with core needle biopsy
    Mulan Li
    Department of Radiology, College of Medicine, Seoul National University, Jongno gu, Seoul, Korea
    PLoS ONE 6:e25563. 2011
    ..Previous HR-MAS MR results have been obtained from post-surgery samples, which limits their direct clinical applicability...
  37. ncbi Generalizing discriminant analysis using the generalized singular value decomposition
    Peg Howland
    Department of Computer Science and Engineering, University of Minnesota, Minneapolis, MN 55455, USA
    IEEE Trans Pattern Anal Mach Intell 26:995-1006. 2004
    b>Discriminant analysis has been used for decades to extract features that preserve class separability. It is commonly defined as an optimization problem involving covariance matrices that represent the scatter within and between clusters...
  38. ncbi Assessment and comparison of different methods for heartbeat classification
    I Jekova
    Centre of Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria
    Med Eng Phys 30:248-57. 2008
    ..the classification abilities of four classification methods--Kth nearest neighbour rule, neural networks, discriminant analysis and fuzzy logic...
  39. ncbi Study of discriminant analysis applied to motor imagery bipolar data
    Carmen Vidaurre
    Dp IEE, Edificio Los Tejos, Public University of Navarre, Campus Arrosadia s n, Pamplona, 31006, Spain
    Med Biol Eng Comput 45:61-8. 2007
    We present a study of linear, quadratic and regularized discriminant analysis (RDA) applied to motor imagery data of three subjects...
  40. ncbi Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets
    Olivier Cloarec
    Biological Chemistry Section, Faculty of Medicine, Biomedical Sciences Division, Imperial College London, South Kensington, London, UK
    Anal Chem 77:1282-9. 2005
    ..of STOCSY with supervised pattern recognition and particularly orthogonal projection on latent structure-discriminant analysis (O-PLS-DA) offers a new powerful framework for analysis of metabonomic data...
  41. ncbi Mass spectrometric and linear discriminant analysis of N-glycans of human serum alpha-1-acid glycoprotein in cancer patients and healthy individuals
    Timea Imre
    Institute of Structural Chemistry, Chemical Research Center, Hungarian Academy of Sciences, Budapest, Pusztaszeri u 59 67, Hungary
    J Proteomics 71:186-97. 2008
    ..ovarian tumor) were analyzed by MALDI-TOF mass spectrometry and a multivariate statistical method (linear discriminant analysis, LDA). 34 different glycan structures have been identified...
  42. ncbi Discriminative feature co-occurrence selection for object detection
    Takeshi Mita
    Multimedia Laboratory, Corporate Research and Development Center, Toshiba Corporation, Kawasaki, Japan
    IEEE Trans Pattern Anal Mach Intell 30:1257-69. 2008
    ....
  43. ncbi Diffuse reflectance spectroscopy for optical soft tissue differentiation as remote feedback control for tissue-specific laser surgery
    Florian Stelzle
    Department of Oral and Maxillofacial Surgery, University Hospital Erlangen, Erlangen, Germany
    Lasers Surg Med 42:319-25. 2010
    ..It is the aim of the study to use this technique on soft tissue samples, to set a technological basis for a remote optical feedback system for tissue-specific laser surgery...
  44. ncbi SR-FTIR spectroscopy of renal epithelial carcinoma side population cells displaying stem cell-like characteristics
    Caryn Hughes
    Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, UK M1 7DN
    Analyst 135:3133-41. 2010
    ..Using the chemometric techniques of Principal Component and Linear Discriminant Analysis (PCA and LDA) for multivariate reduction, biochemical differences between the cells from different sub-..
  45. pmc Classification of individual lung cancer cell lines based on DNA methylation markers: use of linear discriminant analysis and artificial neural networks
    Alberto M Marchevsky
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Mol Diagn 6:28-36. 2004
    ..The data were analyzed with artificial neural networks (ANN) and linear discriminant analysis (LDA) to classify the cell lines into SCLC or into NSCLC...
  46. ncbi Metabolomic investigation into variation of endogenous metabolites in professional athletes subject to strength-endurance training
    Bei Yan
    Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, People s Republic of China
    J Appl Physiol (1985) 106:531-8. 2009
    ..e., principal component analysis (PCA), and partial least squares projection to latent structures and discriminant analysis (PLS-DA) were used to process the data...
  47. ncbi Effects of MRI acquisition parameter variations and protocol heterogeneity on the results of texture analysis and pattern discrimination: an application-oriented study
    Marius E Mayerhoefer
    Department of Radiology, MR Center of Excellence, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Med Phys 36:1236-43. 2009
    ..0 T scanner equipped with a microimaging gradient insert coil. Linear discriminant analysis and k nearest neighbor classification were used for texture-based pattern discrimination...
  48. pmc Shrinkage-based diagonal discriminant analysis and its applications in high-dimensional data
    Herbert Pang
    Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina 27705, USA
    Biometrics 65:1021-9. 2009
    ..Diagonal discriminant analysis, support vector machines, and k-nearest neighbor have been suggested as among the best methods for small ..
  49. ncbi Classification of adolescent psychotic disorders using linear discriminant analysis
    Patricia J Pardo
    The Domenici Research Center for Mental Illness, Brain Sciences Center, Minneapolis Veterans Affairs Medical Center, Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN, 55454, USA
    Schizophr Res 87:297-306. 2006
    ..The differential diagnosis between schizophrenia and bipolar disorder during adolescence presents a major clinical problem. Can these two diagnoses be differentiated objectively early in the courses of illness?..
  50. pmc Subspace projection approaches to classification and visualization of neural network-level encoding patterns
    Remus Osan
    Center for Systems Neurobiology, Department of Pharmacology, Boston University, Boston, Massachusetts, United States of America
    PLoS ONE 2:e404. 2007
    ..Here we systematically employed a series of projection methods, such as Multiple Discriminant Analysis (MDA), Principal Components Analysis (PCA) and Artificial Neural Networks (ANN), and compared them with ..
  51. ncbi Decoding subjective preference from single-trial near-infrared spectroscopy signals
    Sheena Luu
    Institute of Biomaterials and Biomedical Engineering, 164 College Street Room 407, University of Toronto, Toronto, Ontario M5S 3G9, Canada
    J Neural Eng 6:016003. 2009
    ..Using mean signal amplitudes as features and linear discriminant analysis, we were able to decode which drink was preferred on a single-trial basis with an average accuracy of 80%.
  52. ncbi Characterisation of chondrogenic differentiation of human mesenchymal stem cells using synchrotron FTIR microspectroscopy
    Chirapond Chonanant
    Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
    Analyst 136:2542-51. 2011
    ..Classification of independent test spectra using partial least squares discriminant analysis (PLS-DA) could distinguish control and chondrocyte-induced cells with 100% accuracy...
  53. ncbi Regions of interest-based discriminant analysis of DaTSCAN SPECT and FDG-PET for the classification of dementia
    Valentina Garibotto
    Nuclear Medicine and Molecular Imaging Unit, Department of Medical Imaging, Geneva University Hospitals, Geneva, Switzerland
    Clin Nucl Med 38:e112-7. 2013
    ..The aim of this study was to assess the relative contribution of DAT and regional glucose metabolism imaging to the differential diagnosis...
  54. ncbi Fourier transform infrared microspectroscopy reveals that tissue culture conditions affect the macromolecular phenotype of human embryonic stem cells
    Julie Cao
    Monash Immunology and Stem Cell Laboratories, Monash University, Building 75, STRIP 1, West Ring Road, Clayton, Victoria 3800, Australia
    Analyst 138:4147-60. 2013
    ....
  55. ncbi Identification of candidate markers associated with agronomic traits in rice using discriminant analysis
    N Zhang
    Department of Agronomy and Environmental Management, LSU AgCenter, Louisiana State University, Baton Rouge, LA 70803, USA
    Theor Appl Genet 110:721-9. 2005
    ..We have evaluated the potential of discriminant analysis (DA), a multivariate statistical procedure, to detect candidate markers associated with agronomic traits ..
  56. ncbi Predicting class II MHC/peptide multi-level binding with an iterative stepwise discriminant analysis meta-algorithm
    R R Mallios
    Office of Sponsored Projects and Research, University of California, San Francisco, 2615 East Clinton Avenue, Fresno, CA 93703, USA
    Bioinformatics 17:942-8. 2001
    ..An agretope is that portion of a peptide that interacts with an MHC molecule. The identification and prediction of agretopes is the first step towards vaccine design...
  57. ncbi Dual-tracer dopamine transporter and perfusion SPECT in differential diagnosis of parkinsonism using template-based discriminant analysis
    Koenraad Van Laere
    Division of Nuclear Medicine, University Hospital Gasthuisberg and K U Leuven, Leuven, Belgium
    J Nucl Med 47:384-92. 2006
    ....
  58. ncbi Acoustic identification of eight species of bat (mammalia: chiroptera) inhabiting forests of southern hokkaido, Japan: potential for conservation monitoring
    Dai Fukui
    Tomakomai Experimental Forest, Hokkaido University, Takoaka, Japan
    Zoolog Sci 21:947-55. 2004
    ....
  59. ncbi Discriminant analysis to evaluate clustering of gene expression data
    Marco A Mendez
    Laboratorio de Bioinformatica y Expresion Genica, INTA, Universidad de Chile, Macul 5540, Santiago, Chile
    FEBS Lett 522:24-8. 2002
    ..cluster analysis), dimension reduction (principal component analysis) and supervised methods (linear discriminant analysis) in a sequential form...
  60. ncbi Incremental linear discriminant analysis for classification of data streams
    Shaoning Pang
    Knowledge Engineering and Discovery Research Institute, Auckland University of Technology, New Zealand
    IEEE Trans Syst Man Cybern B Cybern 35:905-14. 2005
    ..Basically, we propose an incremental linear discriminant analysis (ILDA) in its two forms: a sequential ILDA and a Chunk ILDA...
  61. ncbi Equivalence of improvement in area under ROC curve and linear discriminant analysis coefficient under assumption of normality
    Olga V Demler
    Department of Biostatistics, Boston University, 801 Massachusetts Avenue, Boston, MA 02118, USA
    Stat Med 30:1410-8. 2011
    ..This paper demonstrates that under the assumption of multivariate normality and employing linear discriminant analysis (LDA) to construct the risk prediction tool, statistical significance of the new predictor(s) is ..
  62. ncbi Sparse partial-least-squares discriminant analysis for different geographical origins of Salvia miltiorrhiza by (1) H-NMR-based metabolomics
    Miaomiao Jiang
    Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, PR China Key Laboratory of TCM Chemistry and Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, PR China Research and Development Center of TCM, Tianjin International Joint Academy of Biotechnology and Medicine, Tianjin, 300457, PR China
    Phytochem Anal 25:50-8. 2014
    ..1) H nuclear magnetic resonance (NMR) spectroscopy has clear advantages in respect of detecting various primary and secondary metabolites in plants simultaneously, non-targeted and non-destructively...
  63. ncbi A comparison approach toward finding the best feature and classifier in cue-based BCI
    R Boostani
    Department of Computer Science and Engineering, School of Engineering, Shiraz University, Shiraz, Iran
    Med Biol Eng Comput 45:403-12. 2007
    ..coefficients, and fractal dimension along with support vector machine (SVM), Adaboost and Fisher linear discriminant analysis (FLDA) classifiers have been assessed...
  64. ncbi Thyroid nodule classification using ultrasound elastography via linear discriminant analysis
    Si Luo
    Department of Electrical Engineering, University of Washington, Seattle, WA 98195, United States
    Ultrasonics 51:425-31. 2011
    ..A classifier was developed based on the linear discriminant analysis (LDA) and used to differentiate the thyroid nodules into two types: (I) no FNA (observation-only) and (II) ..
  65. ncbi Coupling proton transfer reaction-mass spectrometry with linear discriminant analysis: a case study
    Franco Biasioli
    Istituto Agrario di S Michele a A, S Michele, Via E Mach 2, 38010, Italy
    J Agric Food Chem 51:7227-33. 2003
    ..varieties measured on the third to fourth day after harvest could be successfully distinguished by linear discriminant analysis (LDA) on PTR-MS spectra compressed by discriminant partial least squares (dPLS)...
  66. ncbi Classification of malignant gliomas by infrared spectroscopic imaging and linear discriminant analysis
    Christoph Krafft
    Institute for Analytical Chemistry, Dresden University of Technology, 01062 Dresden, Germany
    Anal Bioanal Chem 387:1669-77. 2007
    ..II, astrocytoma grade III, glioblastoma multiforme grade IV, hemorrhage, and other tissue by a linear discriminant analysis model which was trained by data from a single-channel detector...
  67. pmc Discriminant analysis models for early detection of glaucomatous optic disc changes
    M Iester
    Department of Neurological and Visual Sciences, Ophthalmology B, University of Genoa and Division of Ophthalmology of the Gaslini G Institute, Genoa, Italy
    Br J Ophthalmol 84:464-8. 2000
    ..To evaluate and compare four different mathematical formulas for the early detection of morphometric optic nerve head changes in chronic open angle glaucoma...
  68. ncbi Application of multivariate statistical techniques in the assessment of water quality in the Southwest New Territories and Kowloon, Hong Kong
    Xuan Zhang
    College of Environmental Science and Engineering, Nankai University, Tianjin, 300071, People s Republic of China
    Environ Monit Assess 173:17-27. 2011
    ..b>Discriminant analysis (DA) provided better results both temporally and spatially...
  69. ncbi Regularized linear discriminant analysis and its application in microarrays
    Yaqian Guo
    Department of Statistics, Stanford University, Stanford, CA 94305, USA
    Biostatistics 8:86-100. 2007
    In this paper, we introduce a modified version of linear discriminant analysis, called the "shrunken centroids regularized discriminant analysis" (SCRDA)...
  70. ncbi Nonparametric discriminant analysis for face recognition
    Zhifeng Li
    Department of Systems Engineering and Engineering Management, The Chinese University of Hong Kong, Hong Kong
    IEEE Trans Pattern Anal Mach Intell 31:755-61. 2009
    In this paper, we develop a new framework for face recognition based on nonparametric discriminant analysis (NDA) and multi-classifier integration...
  71. ncbi Application of partial least squares discriminant analysis and variable selection procedures: a 2D-PAGE proteomic study
    Emilio Marengo
    Dipartimento di Scienze dell Ambiente e della Vita, Universita degli Studi del Piemonte Orientale, Via Bellini 25 G, 15100, Alessandria, Italy
    Anal Bioanal Chem 390:1327-42. 2008
    ..Here, partial least squares discriminant analysis was applied to improve the results obtained by classic image analysis and to identify the significant ..
  72. pmc Metabolic response to Klebsiella pneumoniae infection in an experimental rat model
    Fangcong Dong
    Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Centre for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, PR China
    PLoS ONE 7:e51060. 2012
    ..Our research provides underlying pathological processes of bacteremia and a better understanding of the clinical and biochemical manifestations of bacteremia...
  73. pmc Discriminative motif discovery in DNA and protein sequences using the DEME algorithm
    Emma Redhead
    Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD, 4072 Australia
    BMC Bioinformatics 8:385. 2007
    ....
  74. pmc Discriminant analysis of Raman spectra for body fluid identification for forensic purposes
    Vitali Sikirzhytski
    Department of Chemistry, University at Albany, SUNY, 1400 Washington Avenue, Albany, NY 12222, USA
    Sensors (Basel) 10:2869-84. 2010
    ..Results demonstrated the capability of Raman spectroscopy to identify an unknown substance to be semen, blood or saliva with high confidence...
  75. ncbi Color image discriminant models and algorithms for face recognition
    Jian Yang
    Department of Computer Science, New Jersey Institute of Technology, Newark, NJ 07102, USA
    IEEE Trans Neural Netw 19:2088-98. 2008
    ..26% at the false accept rate (FAR) of 0.1%...
  76. ncbi Automated classification of multi-spectral MR images using Linear Discriminant Analysis
    Geng Cheng Lin
    Department of Electrical Engineering, National Central University, Jhongli 320, Taiwan, ROC
    Comput Med Imaging Graph 34:251-68. 2010
    ..This work proposes a novel approach called "Unsupervised Linear Discriminant Analysis (ULDA)" to classify and segment the three major tissues, i.e...
  77. ncbi Optimization of human plasma 1H NMR spectroscopic data processing for high-throughput metabolic phenotyping studies and detection of insulin resistance related to type 2 diabetes
    Anthony D Maher
    Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Faculty of Medicine, Imperial College London, South Kensington SW7 2AZ, United Kingdom
    Anal Chem 80:7354-62. 2008
    ..methods such as principal component analysis (PCA), orthogonal projections to latent structures discriminant analysis (O-PLS-DA) and statistical spectroscopic tools such as statistical total correlation spectroscopy (STOCSY),..
  78. ncbi Craniometric relationships among medieval Central European populations: implications for Croat migration and expansion
    Mario Slaus
    Department of Archaeology, Croatian Academy of Sciences and Arts, A Kovacica 5, 10000 Zagreb, Croatia
    Croat Med J 45:434-44. 2004
    ....
  79. ncbi Helical CT evaluation of the chemical composition of urinary tract calculi with a discriminant analysis of CT-attenuation values and density
    Marie France Bellin
    Department of Radiology, Hopital Paul Brousse, AP HP, Université Paris 11, 12 14 av P V Couturier, 94804 Villejuif Cedex, France
    Eur Radiol 14:2134-40. 2004
    ..When the first two ranks of highest probability for the accurate classification of each calculus type were taken into account, all cystine, calcium oxalate monohydrate and brushite calculi were correctly classified...
  80. ncbi Further evidence to show population specificity of discriminant function equations for sex determination using the talus of South African blacks
    Mubarak A Bidmos
    School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, 2193, Johannesburg, South Africa
    J Forensic Sci 49:1165-70. 2004
    ....
  81. ncbi Discriminant analysis of anthropometric and biomotor variables among elite adolescent female athletes in four sports
    Mario Leone
    CHUM Hĵpital Notre Dame, University of Montreal, Canada
    J Sports Sci 20:443-9. 2002
    ..The biomotor variables were maximal aerobic power, muscular endurance and flexibility of the trunk. Discriminant analysis revealed three significant functions (P < 0. 05)...
  82. ncbi Characterisation of non-viable whole barley, wheat and sorghum grains using near-infrared hyperspectral data and chemometrics
    Cushla M McGoverin
    Department of Food Science, Stellenbosch University, Private Bag X1, Matieland, Stellenbosch 7602, South Africa
    Anal Bioanal Chem 401:2283-9. 2011
    ..Viable and non-viable classes for partial least squares-discriminant analysis (PLS-DA) were assigned from PC scores that correlated with incubation time...
  83. ncbi Intrauterine growth restriction alters the metabonome of the serum and jejunum in piglets
    Qinghua He
    State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Centre for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan 430071, P R China
    Mol Biosyst 7:2147-55. 2011
    ....
  84. ncbi Sexual dimorphism in the humerus: a comparative analysis of Chinese, Japanese and Thais
    M Y Iscan
    Department of Anatomy, University of Pretoria, South Africa
    Forensic Sci Int 98:17-29. 1998
    ..These findings confirm those of previous studies that there is a need for group specific metric standards of assessment...
  85. ncbi Discriminant analysis of patients' reasons for choosing or refusing treatments for partial edentulism
    C R Leles
    Department of Prevention and Oral Rehabilitation, School of Dentistry, Federal University of Goias, Goiania, Goias, Brazil
    J Oral Rehabil 36:909-15. 2009
    ..b>Discriminant analysis was used to examine the impact of each reason for a patient's decision to choose or refuse treatment ..
  86. ncbi Liquid chromatography-mass spectrometry-based metabolomic analysis of livers from aged rats
    Nari Son
    Research Division for Emerging Innovation Technology, Korea Food Research Institute, Republic of Korea
    J Proteome Res 11:2551-8. 2012
    ..metabolites of rats aged 6, 12, 18, and 24 months; the MS data were processed by partial least-squares discriminant analysis (PLS-DA) to investigate the discrimination among sample groups...
  87. ncbi Assessment of mild hindlimb lameness during over ground locomotion using linear discriminant analysis of inertial sensor data
    T Pfau
    Structure and Motion Laboratory, Department of Veterinary Basic Sciences, The Royal Veterinary College, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK
    Equine Vet J 39:407-13. 2007
    ..The inertial sensor system can be used to capture 6 degree of freedom movement during over ground locomotion and here was used to quantify tuber coxae movement in nonlame and lame horses...
  88. ncbi [Diagnostic value of clinical indices in syndrome differentiation of chronic hepatitis B: an exploration based on receiver operating characteristic curves and stepwise discriminant analysis]
    Yu Zhao
    Institute of Liver Diseases, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    Zhong Xi Yi Jie He Xue Bao 10:1382-7. 2012
    ....
  89. ncbi Discrimination of the geographical origin of beef by (1)H NMR-based metabolomics
    Youngae Jung
    Seoul Center, Korea Basic Science Institute, Seoul 136 713, Republic of Korea
    J Agric Food Chem 58:10458-66. 2010
    ..Principal component analysis (PCA) and orthogonal projection to latent structure-discriminant analysis (OPLS-DA) showed significant separation between extracts of beef originating from four countries: ..
  90. ncbi Exploratory investigation into mild brain injury and discriminant analysis with high frequency bands (32-64 Hz)
    K E Thornton
    Center for Health Psychology, South Plainfield, NJ, USA
    Brain Inj 13:477-88. 1999
    ..The combination of the discriminants resulted in a 100% accuracy rate for the 39 brain injured subjects for which discriminate values were available...
  91. ncbi Orthogonal fuzzy neighborhood discriminant analysis for multifunction myoelectric hand control
    Rami N Khushaba
    Faculty of Engineering and Information Technology, University of Technology Sydney, NSW 2007, Australia
    IEEE Trans Biomed Eng 57:1410-9. 2010
    ..In this paper, a new dimensionality reduction method, referred to as orthogonal fuzzy neighborhood discriminant analysis (OFNDA), is proposed as a response to such a challenge...
  92. ncbi Near infrared hyperspectral imaging for the evaluation of endosperm texture in whole yellow maize (Zea maize L.) kernels
    Marena Manley
    Department of Food Science, Stellenbosch University, Matieland Stellenbosch, South Africa
    J Agric Food Chem 57:8761-9. 2009
    ..The vitreous and floury endosperm clusters were used to make a partial least-squares discriminant analysis (PLS-DA) model, using four components, with a coefficient of determination (R(2)) for the y data (kernel ..
  93. pmc Graph constrained discriminant analysis: a new method for the integration of a graph into a classification process
    Vincent Guillemot
    Laboratory of Functional Genomics CEA, DSV, IRCM, Evry, France
    PLoS ONE 6:e26146. 2011
    ..We present a method called graph-constrained discriminant analysis (gCDA), which aims to integrate the information contained in one or several GRNs into a classification ..
  94. ncbi Dental morphology and variation in theropod dinosaurs: implications for the taxonomic identification of isolated teeth
    Joshua B Smith
    Department of Earth and Environmental Science, University of Pennsylvania, Philadelphia, PA, USA
    Anat Rec A Discov Mol Cell Evol Biol 285:699-736. 2005
    ..However, the results indicate that expanding the standard should facilitate the identification of numerous types of isolated theropod teeth...
  95. pmc Discriminant analysis of ¹⁸F-fluorothymidine kinetic parameters to predict survival in patients with recurrent high-grade glioma
    Mirwais Wardak
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Clin Cancer Res 17:6553-62. 2011
    ....
  96. ncbi Lactate and glycine-potential MR biomarkers of prognosis in estrogen receptor-positive breast cancers
    Guro F Giskeødegård
    Department of Circulation and Medical Imaging, Norwegian University of Science and Technology NTNU, Trondheim, Norway
    NMR Biomed 25:1271-9. 2012
    ..The data were analyzed by multivariate principal component analysis and partial least-squares discriminant analysis, and the findings of important metabolites were confirmed by spectral integration of the metabolite peaks...
  97. ncbi Osteometric variation in the humerus: sexual dimorphism in South Africans
    M Steyn
    Department of Anatomy, University of Pretoria, South Africa
    Forensic Sci Int 106:77-85. 1999
    ..South African collections are ideal for osteometric analysis, because they are still growing in numbers with cross-sectional representatives from the country...
  98. ncbi Chemometric application in identifying sources of organic contaminants in Langat river basin
    Rozita Osman
    Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia
    Environ Monit Assess 184:1001-14. 2012
    ..This study presented the application of selected chemometric techniques: cluster analysis (CA), discriminant analysis (DA), and principal component analysis (PCA) to classify the pollution sources in Langat river basin based ..
  99. ncbi Spatial assessment of Langat River water quality using chemometrics
    Hafizan Juahir
    Department of Environmental Sciences, Faculty of Environmental Studies, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
    J Environ Monit 12:287-95. 2010
    ..with the assessment of Langat River water quality with some chemometrics approaches such as cluster and discriminant analysis coupled with an artificial neural network (ANN)...
  100. ncbi Local linear discriminant analysis framework using sample neighbors
    Zizhu Fan
    Bio Computing Research Center, Shenzhen Graduate School, Harbin Institute of Technology, Shenzhen, China
    IEEE Trans Neural Netw 22:1119-32. 2011
    The linear discriminant analysis (LDA) is a very popular linear feature extraction approach. The algorithms of LDA usually perform well under the following two assumptions...
  101. ncbi CSF-neurofilament and levodopa tests combined with discriminant analysis may contribute to the differential diagnosis of Parkinsonian syndromes
    B Holmberg
    Institute of Clinical Neuroscience, Department of Neurology, University of Goteborg, Sahlgrenska University Hospital, 413 45, Sweden
    Parkinsonism Relat Disord 8:23-31. 2001
    ..As they are pathologically unrelated, the diagnostic precision increases compared to clinical diagnoses when they are combined...

Research Grants62

  1. Neural Representation of Reach-to-Grasp for Cortical FES Neuroprostheses
    Abidemi Bolu Ajiboye; Fiscal Year: 2012
    ..Offline discriminant analysis (DA) models will assess how well the neural activities of these imagined and performed hand postures can ..
  2. METABOLITE BIOIMARKERS IN THE DEVELOPMENT OF ESOPHAGEAL ADENOCARCINOMA
    Thomas L Vaughan; Fiscal Year: 2013
    ..models for sample classification (BE-GERD and HGD/EA-BE) will be constructed using partial least-squares discriminant analysis, and model performance estimated by Monte Carlo cross-validation...
  3. Inflammatory Transcripts, Genes and Positive Valence System Function in Anhedonia
    JERZY ALEKSANDER BODURKA; Fiscal Year: 2013
    ..within this network are inter-correlated, we will use the covariance matrix formed by the mRNA levels in discriminant analysis type-functions to classify cases on the basis of having elevated or non-elevated gene network activity...
  4. Computational tools for T- and B-cell epitope prediction
    Werner A Braun; Fiscal Year: 2010
    ..will be used in combination with a partial least squares approach to reduce the number of variables in the discriminant analysis and in artificial neural networks...
  5. Communication Ability and Work Re-Entry in Adults with Brain Injury
    PETER A MEULENBROEK; Fiscal Year: 2012
    ..Both groups will be administered the tests identified in Aim 1, and discriminant analysis using logistic regression will be used to test the hypothesis that communication variables differentiate ..
  6. Profiling Plasma Unbound Free Fatty Acids for Early Detection of Stroke
    ALAN MARC KLEINFELD; Fiscal Year: 2010
    ..Using linear discriminant analysis, stroke classifiers will be constructed from the FFAu profiles and from the set of probe responses...
  7. Peripheral Biomarkers in Familial Alzheimer's Disease
    Paul Coleman; Fiscal Year: 2009
    ..Statistical analysis of these data will be by means of multivariate discriminant analysis, as we have done in our earlier work...
  8. Adolescent trauma, psychopathology and resilience: A person-focused approach
    Beth S Rosenthal; Fiscal Year: 2012
    ..be accomplished by the use of the statistical procedures multivariable analysis of variance and multiple discriminant analysis. Psychopathology associated with exposure to traumatic events is arguably the most common mental health ..
  9. GENETIC ANALYSIS OF ALTERED IMMUNITY IN CELIAC DISEASE
    JOSEPH MICHALSKI; Fiscal Year: 1990
    ..e., detection of "carriers". Pedigree discriminant analysis of the multivariate data on each member of the pedigrees will be used to define a constellation of immune ..
  10. Interval Timing and Motor Programming by Cortico-Striatal Ensembles
    Miguel A L Nicolelis; Fiscal Year: 2013
    ..We will use neural decoding algorithms (Wiener filter, Kalman filter, discriminant analysis and Markov chains) to extract both temporal and spatial characteristics of motor patterns from large ..
  11. VISUAL FUNCTION IN RETINAL ISCHEMIA
    Mary Johnson; Fiscal Year: 1992
    ..Linear discriminant analysis will be performed separately on these groups, in order to determine which ERG and clinical variables ..
  12. Identification of Clinically Relevant TMD Subtypes Using Cluster Analysis
    Eric Bair; Fiscal Year: 2013
    ..We further hypothesize that TMD-free controls can be grouped into similar clusters. 2. Using discriminant analysis, logistic regression, and more advanced machine learning methods, we will develop rules for classifying ..
  13. Quantitative Methods for Spectral and Image Data in Proteomics Research
    Timothy W Randolph; Fiscal Year: 2010
    ..discrimination analysis methods that build on aims 1 and 2, as well as a developing "functional" discriminant analysis as an alternative for certain technologies in which a simple peak list may ignore subtle or low-abundant ..
  14. Risk for Workplace Violence in Long-Haul Truckers
    Debra Anderson; Fiscal Year: 2004
    ..Dependent on the specific aim, bivariate relationships, logistic regression, discriminant analysis, Cronbach's alpha, and ANCOVA will be used...
  15. Speech Intelligibility Testing in Children with Repaired Cleft Palate
    David Zajac; Fiscal Year: 2007
    ..Multiple regression and descriptive discriminant analysis techniques will be employed...
  16. WHAT DAMAGE DOES VAGINAL BIRTH CAUSE
    John DeLancey; Fiscal Year: 2000
    ..interactions have at least an 80% probability of correct prediction of SI compared with PC or NC by using discriminant analysis. 3) Construct a predictive model for SUI using discriminant functions and classification trees to indicate ..
  17. SBIR PHASE II- TOPIC 234- AUTOMATED PATTERN RECOGNITION IN SATELLITE IMAGERY
    PIERRE E GOOVAERTS; Fiscal Year: 2009
    ..software, automatic identification of environmental exposure patterns through space-time interpolation and discriminant analysis, animated display and query of pattern analysis results, and exploration of relationships between exposure ..
  18. Metabolomic and Isotopomer Analysis of Xenobiotic Stress
    Henri Brunengraber; Fiscal Year: 2009
    ..A number of techniques will be evaluated, including Principal Component Analysis, Fisher Discriminant Analysis and Partial Least Squares. 2...
  19. A PROSPECTIVE STUDY OF PERSONALITY AND RISK OF CANCER
    RICHARD SHEKELLE; Fiscal Year: 1980
    ..In addition, item analysis and discriminant analysis will be used to search for other aspects of personality that may be related to cancer incidence...
  20. Rett syndrome: determinants of outcome and burden
    Helen Leonard; Fiscal Year: 2007
    ..regression models to examine effects of different variables on child and family level outcomes and discriminant analysis, recursive partitioning and machine learning to identify genotype/phenotype associations at the individual ..
  21. MEDICALLY TREATED AND FATAL SUICIDE ACTS: NUMBER & COST
    Ted Miller; Fiscal Year: 2002
    ..2) Using the pooled state data and CHAID tree-building tools, to develop and validate a discriminant analysis model for estimating injury causes from national or state hospital discharge data without E-codes...
  22. Proteomics Approaches to Interstitial Cystitis.
    Brian Liu; Fiscal Year: 2006
    ..e., hierarchical cluster analysis and K-means methods, canonical correlations, discriminant analysis, Bayesian statistics, self-organizing maps and neural networks) that can stratify samples according to ..
  23. A Virtual Reality Environment for Genomic Data Visualization
    Fatima Merchant; Fiscal Year: 2007
    ..select among a number of data projection techniques, including principal component analysis (PCA), linear discriminant analysis (LDA), singular value decomposition (SVD), multi-dimensional scaling (MDS), projection pursuit (PP), self-..
  24. BEHAVIOR CHANGE EFFECTED BY BSE EDUCATIONAL PROGRAMS
    CAROLE CHRVALA; Fiscal Year: 1990
    ..and proficiency of BSE practice between each of the treatment groups, and multiple regression and discriminant analysis to identify those variables that differentiate between performers and non-performers of BSE as well as ..
  25. Tree Ensemble Regression and Classification Methods
    JAMES SCHIMERT; Fiscal Year: 2004
    ..This proposed software will enable medical researchers to obtain high prediction accuracy, and complement traditional tools like discriminant analysis, linear and logistic regression models, and the Cox model.
  26. PATTERN RECOGNITION IN NUCLEIC ACID SEQUENCE DATABASES
    Christian Burks; Fiscal Year: 1991
    ..These measures will be combined through discriminant analysis to create an algorithm that predicts whether or not a potential donor or acceptor site is functional...
  27. DETECTION OF ALCOHOLISM AND HEAVY ALCOHOL INTAKE
    ARTHUR CHAN; Fiscal Year: 1993
    ..Researchers have shown that the use of discriminant analysis (DA) of blood chemistries can classify with high accuracy alcoholics or heavy drinkers...
  28. Provider Attitudes and Performance: Responses to Pay-for-Quality Incentives
    Anthony Waddimba; Fiscal Year: 2007
    ..a modification of the theory of planned[unreadable] behavior (TPB), and the empirical methods of multiple discriminant analysis and structural[unreadable] equation modeling, we will determine a multivariable model of provider ..
  29. COMPUTER-AIDED RESEARCH ON NURSING DIAGNOSIS
    Betty Chang; Fiscal Year: 1992
    ..formulated by a panel of 10 clinical nurse specialists for 10 actual patients; aim (4): performance of a discriminant analysis and testing the discriminant model with data from 414 patients; aim (5): expert opinion evaluations of ..
  30. ELECTROPHYSIOLOGY OF CANNABINOID ACTION ON RAT BEHAVIORS
    Jing Yu Chang; Fiscal Year: 2001
    ..Ensemble activity of many neurons in relation to behavioral events will be examined using discriminant analysis. The goal of this research is to test the hypothesis that cannabinoids act to selectively disrupt ..
  31. AIDS EDUCATION TO I.V. DRUG USERS AND SEXUAL PARTNERS
    Richard Stephens; Fiscal Year: 1991
    ..Analysis of covariance, discriminant analysis and LISREL are proposed as potential data analytic techniques.
  32. INTELLIGENT MAPPING OF GENE EXPRESSION PROFILES
    Yue Wang; Fiscal Year: 2000
    ..The innovative nature of the research relies on the concept of combining (1) a hybrid stepwise nonlinear discriminant analysis for biomarker identification and (2) a hierarchical visual exploration of multi-foci high-dimensional ..
  33. INTELLIGENT MAPPING OF GENE EXPRESSION PROFILES
    Yue Wang; Fiscal Year: 2002
    ..The innovative nature of the research relies on the concept of combining (1) a hybrid stepwise nonlinear discriminant analysis for biomarker identification and (2) a hierarchical visual exploration of multi-foci high-dimensional ..
  34. CLINICAL MEASUREMENTS OF OPTIC NERVE DAMAGE IN GLAUCOMA
    Joseph Caprioli; Fiscal Year: 2004
    ..b>Discriminant analysis and neural networks will be used to test the effectiveness of combined measures, and to estimate the ..
  35. MAXIMIZING POSTOPERATIVE FUNCTIONAL OUTCOMES IN ELDERS
    Valerie Lawrence; Fiscal Year: 1999
    ..Caregiver burden and health resource utilization will be evaluated at postoperative follow up visits. Discriminant analysis will be used to evaluate the relationship between preoperative status for primary determinants and ..
  36. DEMONSTRATION OF CASE MANAGEMENT AND SUPPORTED HOUSING
    Michael Sosin; Fiscal Year: 1992
    ..The outcome evaluation also determines whether interventions are more effective for some individuals than for others. Data analysis relies on analysis of covariance, logistic regression, and discriminant analysis.
  37. Statistical analysis of radionuclide images
    Song Lai; Fiscal Year: 2006
    ..Two methods, a pixel-based logistic discriminant analysis system and a channelized Hotelling observer, will be "trained" on known images, and then used to ..
  38. COPING WITH CAD AFTER MI--PREDICTIVE MODEL FOR NURSING
    MARIE DRIEVER; Fiscal Year: 1990
    ..A discriminant analysis procedure will be used to compare survivors and nonsurvivors on selected variables of the coping process...
  39. NEW STATISTICAL METHODS FOR MEDICAL SIGNALS AND IMAGES
    Iain Johnstone; Fiscal Year: 2002
    ..To study covariance structure, the project proposes "sparse" forms of principal components and discriminant analysis that may be more sensitive to either local phenomena of not necessarily smooth form or that are more ..
  40. Adipose Metabolic Profiling for Obesity Drug Targeting
    Kyongbum Lee; Fiscal Year: 2005
    ..parallel metabolic flux libraries using established modeling methodologies, d) Perform multivariate discriminant analysis on the metabolite and flux libraries to identify significant markers for each of the growth conditions...
  41. SERVICE USE BY IMPAIRED ELDERLY AND INFORMAL CAREGIVERS
    LINDA NOELKER; Fiscal Year: 1993
    ..These include: multiple and logistic regression, discriminant analysis, exploratory factor analysis, and LISREL analysis.
  42. TC-99M NGA IN THE EVALUATION OF LIVER DISEASE
    ROBERT STADALNIK; Fiscal Year: 1992
    ..With the discriminant analysis method, classification of disease presence and disease category can be accomplished...
  43. COMPARISON OF IMP & HMPAO CEREBRAL SPECT IN ALZHEIMERS
    Christopher van Dyck; Fiscal Year: 1991
    ..An analysis of variance and a discriminant analysis will be performed in order to determine which combination of radiopharmaceutical and ROI maximally ..
  44. Smoking Relapse among Mothers of Infants
    KATHLEEN GAFFNEY; Fiscal Year: 2003
    ..Data analysis will include multiple and logistic regression, discriminant analysis, and canonical correlation models. Implications for practice, research, and policy will be disseminated...
  45. Structure and dynamics of DNA hairpins
    GERARD HARBISON; Fiscal Year: 2005
    ..with which conformation can be determined from chemical shift and shielding tensors data by the methods of discriminant analysis, and this statistical information will be incorporated as a weighting factor in refinement protocols for ..
  46. Proteomics software package for the detection of cancer
    Maciek Sasinowski; Fiscal Year: 2003
    ..and modified statistical approaches for signal conditioning (Wiener filters) and classification (linear discriminant analysis, principal components analysis, support vector machines, Bayes method) of SELDI data derived from analysis ..
  47. Molecular Fingerprinting of Breast Cancer Development
    Vladimir Shulaev; Fiscal Year: 2009
    ..These fingerprints are processed with variable selection and discriminant analysis algorithms from which the determinant molecules for each stage of breast cancer development will be ..
  48. Expression profiling of human islets
    KLAUS KAESTNER; Fiscal Year: 2006
    ..Second, we will apply discriminant analysis to the microarray data to identify a set of up to 96 genes that are most predictive of islet function...
  49. Generalized Anxiety Disorder in Older Adults
    Margaret Anne Mackintosh; Fiscal Year: 2006
    ..The impact of personality traits on lifetime GAD will be assessed using non-parametric multiple discriminant analysis. Finally, to assess the role of genetic and environmental factors on lifetime GAD, behavior genetic models ..
  50. INFANT GROWTH FAILURE AND NURSING CARE
    MARILYN STEMBER; Fiscal Year: 1992
    ..b>Discriminant analysis using linear or logistic regression methods will be used in Aim 3 for developing the framework for a risk ..
  51. ABUSE/DISTRESS MODEL OF DRUG TREATMENT ENGAGEMENT
    Robert Fiorentine; Fiscal Year: 1999
    ..Along with OLS and logistic regressions, repeated measures, discriminant analysis, and other multivariate statistical applications, structural equations modeling (EQS) will be utilized to ..
  52. ULTRASONIC PROPERTIES OF NORMAL AND PATHOLOGICAL TISSUES
    PETER EDMONDS; Fiscal Year: 1993
    ..In particular, we seek to discriminate benign from malignant states. Discriminant analysis using the jackknifing technique, classification and regression trees, and neural net analyses will be ..
  53. Multimodality CAD system with image references for breast mass characterization
    Berkman Sahiner; Fiscal Year: 2007
    ..Any reduction in this number without a decrease in breast cancer detection sensitivity will decrease health care costs, as well as contribute to the well-being of the patient by reducing anxiety and morbidity. ..
  54. Cognitive Brain Activity: Aging and Dementia
    Robert Chapman; Fiscal Year: 2007
    ..Multivariate statistics are used to measure the ERP components and to develop functions that discriminate among the subject groups and predict AD among the MCI patients. [unreadable] [unreadable]..
  55. Digital Mammography: Advanced Computer-Aided Breast Can*
    Heang Ping Chan; Fiscal Year: 2007
    ..abstract_text> ..
  56. Biomarkers of Aging in the Sera Metabolome
    Bruce Kristal; Fiscal Year: 2005
    ..g., 1 and 2-D clustering, heat maps, self-organizing maps, principal components analysis, partial least squares, partial least squares projection to latent structures discriminant analysis, etc).
  57. Computer Aided Diagnosis of Lung Cancer
    Heang Ping Chan; Fiscal Year: 2006
    ..When fully developed and clinically implemented, a CAD system for lung nodules will increase the efficacy of lung cancer screening with helical CT, improve early detection, and improve the chance of survival of patients. ..
  58. Three-Class ROC Analysis for Task-Based Medical Image Quality Assessment
    Xin He; Fiscal Year: 2008
    ..proposed a three- class ROC analysis method that extends and unifies the decision theoretic, linear discriminant analysis and probabilistic foundations of binary ROC in a three-class paradigm...
  59. Behavioral Interventions for Low Back Pain
    STEVEN GEORGE; Fiscal Year: 2007
    ....
  60. Lung Imaging Database Resource for Imaging Research
    MIKE MCNITT GRAY; Fiscal Year: 2006
    ..SA-3 To provide a means for documentation and distribution of this database to researchers through the internet. ..
  61. Monte Carlo Based Patient Radiation Dose from CT
    Michael McNitt Gray; Fiscal Year: 2008
    ..can be obtained without performing all aspects of the detailed analysis and modeling. [unreadable] [unreadable]..
  62. Pharmacogenetics in Tourette Syndrom
    Harvey Singer; Fiscal Year: 2004
    ..The identification of genetic polymorphisms that are associated with clinical disease or treatment success, has obvious benefits. ..