Genomes and Genes
Summary: Regular course of eating and drinking adopted by a person or animal. This does not include DIET THERAPY, a specific diet prescribed in the treatment of a disease.
Publications270 found, 100 shown here
- Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control studySalim Yusuf
Population Health Research Institute, Hamilton General Hospital, 237 Barton Street East, Hamilton, Ontario, Canada L8L 2X2
Lancet 364:937-52. 2004..Therefore, the effect of such factors on risk of coronary heart disease in most regions of the world is unknown...
- Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humansBrian D Muegge
Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO 63108, USA
Science 332:970-4. 2011..of bacterial 16S ribosomal RNA genes to gain an understanding of how microbial communities adapt to extremes of diet. We sampled fecal DNA from 33 mammalian species and 18 humans who kept detailed diet records, and we found that the ..
- Obesity in children and young people: a crisis in public healthT Lobstein
IASO International Obesity TaskForce, 231 North Gower Street, London NW1 2NS, UK
Obes Rev 5:4-104. 2004
- Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspringSheau Fang Ng
Department of Pharmacology, School of Medical Sciences, University of New South Wales, New South Wales, Sydney 2052, Australia
Nature 467:963-6. 2010..Although the detrimental impacts of diet-induced maternal obesity on adiposity and metabolism in offspring are well established, the extent of any ..
- Changes in diet and lifestyle and long-term weight gain in women and menDariush Mozaffarian
Division of Cardiovascular Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
N Engl J Med 364:2392-404. 2011..Specific dietary and other lifestyle behaviors may affect the success of the straightforward-sounding strategy "eat less and exercise more" for preventing long-term weight gain...
- Mechanisms underlying the resistance to diet-induced obesity in germ-free miceFredrik Backhed
Center for Genome Sciences and Department of Medicine, Washington University School of Medicine, St Louis, MO 63108, USA
Proc Natl Acad Sci U S A 104:979-84. 2007..GF) animals are protected against the obesity that develops after consuming a Western-style, high-fat, sugar-rich diet. Their persistently lean phenotype is associated with increased skeletal muscle and liver levels of phosphorylated ..
- Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular diseasePenny M Kris-Etherton
Circulation 106:2747-57. 2002
- Dominant and diet-responsive groups of bacteria within the human colonic microbiotaAlan W Walker
Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, UK
ISME J 5:220-30. 2011..Volunteers were provided successively with a control diet, diets high in resistant starch (RS) or non-starch polysaccharides (NSPs) and a reduced carbohydrate weight loss (..
- Origins and evolution of the Western diet: health implications for the 21st centuryLoren Cordain
Department of Health and Exercise Science, Colorado State University, Fort Collins, CO 80523, USA
Am J Clin Nutr 81:341-54. 2005There is growing awareness that the profound changes in the environment (eg, in diet and other lifestyle conditions) that began with the introduction of agriculture and animal husbandry approximately 10000 y ago occurred too recently on ..
- Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiomePeter J Turnbaugh
Center for Genome Sciences, Washington University, St Louis, MO 63108, USA
Cell Host Microbe 3:213-23. 2008We have investigated the interrelationship between diet, gut microbial ecology, and energy balance using a mouse model of obesity produced by consumption of a prototypic Western diet...
- Globalization of diabetes: the role of diet, lifestyle, and genesFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
Diabetes Care 34:1249-57. 2011..Nonetheless, interactions between Westernized diet and lifestyle and genetic background may accelerate the growth of diabetes in the context of rapid nutrition ..
- A high-sugar diet produces obesity and insulin resistance in wild-type DrosophilaLaura Palanker Musselman
Division of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
Dis Model Mech 4:842-9. 2011..Larvae reared on a high-sugar diet were hyperglycemic, insulin resistant and accumulated fat--hallmarks of T2D--compared with those reared on control ..
- The contextual effect of the local food environment on residents' diets: the atherosclerosis risk in communities studyKimberly Morland
Department of Epidemiology, University of North Carolina, Chapel Hill, USA
Am J Public Health 92:1761-7. 2002..We studied the association between the local food environment and residents' report of recommended dietary intake...
- Gut microbiota composition correlates with diet and health in the elderlyMarcus J Claesson
Department of Microbiology, University College Cork, Ireland
Nature 488:178-84. 2012..However, clustering of subjects by diet separated them by the same residence location and microbiota groupings...
- A systematic review of the evidence supporting a causal link between dietary factors and coronary heart diseaseAndrew Mente
Population Health Research Institute, Hamilton General Hospital, 4 East Room 441, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Arch Intern Med 169:659-69. 2009..Although a wealth of literature links dietary factors and coronary heart disease (CHD), the strength of the evidence supporting valid associations has not been evaluated systematically in a single investigation...
- High-fat diet determines the composition of the murine gut microbiome independently of obesityMarie A Hildebrandt
Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Gastroenterology 137:1716-24.e1-2. 2009The composition of the gut microbiome is affected by host phenotype, genotype, immune function, and diet. Here, we used the phenotype of RELMbeta knockout (KO) mice to assess the influence of these factors.
- Interactions and competition within the microbial community of the human colon: links between diet and healthHarry J Flint
Microbial Ecology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB219SB, UK
Environ Microbiol 9:1101-11. 2007..of the human intestinal tract play an important role in health, in particular by mediating many of the effects of diet upon gut health...
- Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant miceCharlotte Bonnard
INSERM, U870, IFR62, Oullins, France
J Clin Invest 118:789-800. 2008..during the development of insulin resistance and progression to diabetes in mice fed a high-fat, high-sucrose diet. Although 1 month of high-fat, high-sucrose diet feeding was sufficient to induce glucose intolerance, mice showed ..
- Identifying risk for obesity in early childhoodPhilip R Nader
Division of Community Pediatrics, University of California, San Diego, California, USA
Pediatrics 118:e594-601. 2006..Our aim with this study was to assist clinicians by estimating the predictive value of earlier levels of BMI status on later risk of overweight and obesity during the middle childhood and early adolescent years...
- Neighborhood environments: disparities in access to healthy foods in the U.SNicole I Larson
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55454, USA
Am J Prev Med 36:74-81. 2009..S. This article reviews research relating to the presence, nature, and implications of neighborhood differences in access to food...
- Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse modelsE F Murphy
Alimentary Pharmabiotic Centre, University College Cork, Ireland
Gut 59:1635-42. 2010..However, a causal relationship is unproven and contributory variables include diet, genetics and age...
- Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research GroupF M Sacks
Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
N Engl J Med 344:3-10. 2001..effect of different levels of dietary sodium, in conjunction with the Dietary Approaches to Stop Hypertension (DASH) diet, which is rich in vegetables, fruits, and low-fat dairy products, in persons with and in those without hypertension.
- ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial treeY Nakashima
Department of Pathology, University of Washington, Seattle 98195
Arterioscler Thromb 14:133-40. 1994..In the present study, the animals were fed either chow or a high-fat, Western-type diet and examined at ages ranging from 6 to 40 weeks...
- Fast food restaurants and food stores: longitudinal associations with diet in young to middle-aged adults: the CARDIA studyJanne Boone-Heinonen
Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516 3997, USA
Arch Intern Med 171:1162-70. 2011....
- Dairy consumption, obesity, and the insulin resistance syndrome in young adults: the CARDIA StudyMark A Pereira
Department of Medicine, Children s Hospital, 300 Longwood Ave, Boston, MA 02115, USA
JAMA 287:2081-9. 2002..Although diet has been postulated to influence IRS, the independent effects of dairy consumption on development of this syndrome ..
- Differences in weight status and energy-balance related behaviors among schoolchildren across Europe: the ENERGY-projectJohannes Brug
Department of Epidemiology and Biostatistics and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
PLoS ONE 7:e34742. 2012..Current data on the prevalence of overweight and energy-balance behaviors among European children is necessary to inform overweight prevention interventions...
- The preventable causes of death in the United States: comparative risk assessment of dietary, lifestyle, and metabolic risk factorsGoodarz Danaei
Harvard School of Public Health, Boston, MA, USA
PLoS Med 6:e1000058. 2009....
- Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesityCarey N Lumeng
Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA
Diabetes 56:16-23. 2007..We hypothesized that ATMs recruited to adipose tissue during a high-fat diet have unique inflammatory properties compared with resident tissue ATMs...
- Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J miceMasuko Kobori
National Food Research Institute, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan
Mol Nutr Food Res 55:530-40. 2011To determine the effect of consumption of a quercetin-rich diet on obesity and dysregulated hepatic gene expression.
- Specificity of polysaccharide use in intestinal bacteroides species determines diet-induced microbiota alterationsErica D Sonnenburg
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
Cell 141:1241-52. 2010The intestinal microbiota impacts many facets of human health and is associated with human diseases. Diet impacts microbiota composition, yet mechanisms that link dietary changes to microbiota alterations remain ill-defined...
- Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition CommitteeAlice H Lichtenstein
Circulation 114:82-96. 2006Improving diet and lifestyle is a critical component of the American Heart Association's strategy for cardiovascular disease risk reduction in the general population. This document presents recommendations designed to meet this objective...
- Systematic review of school-based interventions that focus on changing dietary intake and physical activity levels to prevent childhood obesity: an update to the obesity guidance produced by the National Institute for Health and Clinical ExcellenceT Brown
School of Health and Social Care, University of Teesside, Middlesbrough, UK
Obes Rev 10:110-41. 2009..One of three diet studies, five of 15 physical activity studies and nine of 20 combined diet and physical activity studies ..
- Inflammation: the link between insulin resistance, obesity and diabetesParesh Dandona
Division of Endocrinology, Diabetes and Metabolism, State University of New York at Buffalo and Kaleida Health, 3 Gates Circle, Buffalo, NY 14209, USA
Trends Immunol 25:4-7. 2004..This might interfere with the anti-inflammatory effect of insulin, which in turn might promote inflammation...
- Global nutrition dynamics: the world is shifting rapidly toward a diet linked with noncommunicable diseasesBarry M Popkin
University of North Carolina, Chapel Hill, NC, USA
Am J Clin Nutr 84:289-98. 2006..Dietary changes appear to be shifting universally toward a diet dominated by higher intakes of animal and partially hydrogenated fats and lower intakes of fiber...
- Actual causes of death in the United States, 2000Ali H Mokdad
Division of Adult and Community Health, Centers for Disease Control and Prevention, Atlanta, GA, USA
JAMA 291:1238-45. 2004..Modifiable behavioral risk factors are leading causes of mortality in the United States. Quantifying these will provide insight into the effects of recent trends and the implications of missed prevention opportunities...
- The global burden of disease attributable to low consumption of fruit and vegetables: implications for the global strategy on dietKaren Lock
European Centre on Health of Societies in Transition, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
Bull World Health Organ 83:100-8. 2005....
- Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic isletsIonel Sandovici
Metabolic Research Laboratories, Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge CB2 0SW, United Kingdom
Proc Natl Acad Sci U S A 108:5449-54. 2011..One such factor that is known to play an important role in determining long-term metabolic health is diet during critical periods of development...
- The continuing epidemics of obesity and diabetes in the United StatesA H Mokdad
Data Management Division, National Immunization Program, Centers for Disease Control and Prevention, MS E62, 1600 Clifton Rd, NE, Atlanta, GA 30333, USA
JAMA 286:1195-200. 2001..Recent reports show that obesity and diabetes have increased in the United States in the past decade...
- The role of diet in the prevention of type 2 diabetesJ Salas-Salvado
Human Nutrition Unit, Hospital Universitari Sant Joan de Reus, Biochemistry and Biotechnology Department, IISPV, Universitat Rovira i Virgili, Reus, Spain
Nutr Metab Cardiovasc Dis 21:B32-48. 2011..Landmark clinical trials of lifestyle changes in subjects with prediabetes have shown that diet and exercise leading to weight loss consistently reduce the incidence of diabetes...
- Test-retest reliability and construct validity of the ENERGY-child questionnaire on energy balance-related behaviours and their potential determinants: the ENERGY-projectAmika S Singh
VU University Medical Center, EMGO Institute for Health and Care Research, Dpt, of Public and Occupational Health, Amsterdam, The Netherlands
Int J Behav Nutr Phys Act 8:136. 2011..Therefore, reliable and valid tools to measure these variables in large-scale population research are needed...
- DNA barcoding for ecologistsAlice Valentini
Laboratoire d Ecologie Alpine, Universite Joseph Fourier, BP 53, 38041 Grenoble Cedex 9, France
Trends Ecol Evol 24:110-7. 2009..Even DNA-based diet composition can be estimated using fecal samples...
- Systematic review of clinical trials on dietary interventions to prevent excessive weight gain during pregnancy among normal weight, overweight and obese womenIda Tanentsapf
Faculty of Health Sciences, Copenhagen University, Panum Instituttet, Copenhagen, Denmark
BMC Pregnancy Childbirth 11:81. 2011..The primary objective of this review was to evaluate the effect of dietary interventions for reducing GWG. The secondary objective was to examine the impact of these interventions on different child and maternal health outcomes...
- Changing diet and physical activity to reduce gestational weight gain: a meta-analysisB Gardner
Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London, London, UK
Obes Rev 12:e602-20. 2011..Intervention developers have assumed that adopting a healthier diet and increasing physical activity in pregnancy can limit weight gain, but evaluations of such interventions have ..
- Can gestational weight gain be modified by increasing physical activity and diet counseling? A meta-analysis of interventional trialsIna Streuling
Division of Epidemiology, Institute of Social Pediatrics and Adolescent Medicine, Ludwig Maximilians University of Munich, Munich, Germany
Am J Clin Nutr 92:678-87. 2010..It is therefore of interest whether GWG can be modified by an intervention combining dietary counseling and physical activity...
- Empirically derived eating patterns using factor or cluster analysis: a reviewP K Newby
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
Nutr Rev 62:177-203. 2004..Although the research considered herein has created a meaningful body of literature, refining both the factor and cluster analysis methods will help to further establish eating patterns as a sound dietary assessment method...
- Dietary patterns of adolescents and risk of obesity and hypertensionSarah A McNaughton
Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, 3125 Melbourne, Australia
J Nutr 138:364-70. 2008..This study suggests that specific dietary patterns are already evident in adolescence and a dietary pattern rich in fruit, salad, cereals, and fish pattern may be associated with diastolic blood pressure in older adolescents...
- Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysisPatrice Carter
Diabetes Research, Department of Cardiovascular Sciences, University of Leicester, Leicester LE1 5WW
BMJ 341:c4229. 2010..To investigate the independent effects of intake of fruit and vegetables on incidence of type 2 diabetes...
- Flavonoid intake and risk of chronic diseasesPaul Knekt
National Public Health Institute, Helsinki, Finland
Am J Clin Nutr 76:560-8. 2002..Flavonoids are effective antioxidants and may protect against several chronic diseases...
- Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient miceNicholas M Morton
Endocrinology Unit, Molecular Medicine Centre, University of Edinburgh, Western General Hospital, Edinburgh, UK
Diabetes 53:931-8. 2004..These data provide the first in vivo evidence that adipose 11 beta-HSD-1 deficiency beneficially alters adipose tissue distribution and function, complementing the reported effects of hepatic 11 beta-HSD-1 deficiency or inhibition...
- Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysisD S Ludwig
Department of Medicine, Children s Hospital, Boston, MA 02115, USA
Lancet 357:505-8. 2001..The rising prevalence of obesity in children has been linked in part to the consumption of sugar-sweetened drinks. Our aim was to examine this relation...
- Associations of the local food environment with diet quality--a comparison of assessments based on surveys and geographic information systems: the multi-ethnic study of atherosclerosisLatetia V Moore
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48103, USA
Am J Epidemiol 167:917-24. 2008There is growing interest in understanding how food environments affect diet, but characterizing the food environment is challenging...
- Food store types, availability, and cost of foods in a rural environmentAngela D Liese
Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
J Am Diet Assoc 107:1916-23. 2007..To characterize the built nutritional environment in terms of types and number of food stores, availability, and cost of selected food items in a rural area...
- Two neurons mediate diet-restriction-induced longevity in C. elegansNicholas A Bishop
Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
Nature 447:545-9. 2007..However, no causal role of any hormonal signal in diet-restricted longevity has been demonstrated...
- The local food environment and diet: a systematic reviewCaitlin E Caspi
Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02114, USA
Health Place 18:1172-87. 2012..the problem of obesogenic environments, there has not been a comprehensive review evaluating the food environment-diet relationship...
- Cognitive deficit in 7-year-old children with prenatal exposure to methylmercuryP Grandjean
Institute of Community Health, Odense University, Denmark
Neurotoxicol Teratol 19:417-28. 1997..The effects on brain function associated with prenatal methylmercury exposure therefore appear widespread, and early dysfunction is detectable at exposure levels currently considered safe...
- Primary prevention of gestational diabetes mellitus and large-for-gestational-age newborns by lifestyle counseling: a cluster-randomized controlled trialRiitta Luoto
UKK Institute for Health Promotion Research, Tampere, Finland
PLoS Med 8:e1001036. 2011..Our objective was to examine whether gestational diabetes mellitus (GDM) or newborns' high birthweight can be prevented by lifestyle counseling in pregnant women at high risk of GDM...
- Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in miceChenhong Zhang
Laboratory of Molecular Microbial Ecology and Ecogenomics, Department of Biological Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, PR China
ISME J 4:232-41. 2010Both genetic variations and diet-disrupted gut microbiota can predispose animals to metabolic syndromes (MS)...
- Diet-induced obesity in female mice leads to offspring hyperphagia, adiposity, hypertension, and insulin resistance: a novel murine model of developmental programmingAnne Maj Samuelsson
Division of Reproduction and Endocrinology, King s College London, London, UK
Hypertension 51:383-92. 2008..We investigated the effects of maternal diet-induced obesity in mice on offspring metabolic and cardiovascular function...
- Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver diseaseAnna Alisi
Unit of Metabolic and Autoimmune Liver Diseases, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
Lab Invest 91:283-93. 2011..To this aim, Sprague-Dawley rats were fed ad libitum for 3 months with different diets: standard diet (SD), diet enriched in fats and low in carbohydrates (HFD), SD with high fructose (SD-HF) and diet with high levels ..
- Dietary intake and the development of the metabolic syndrome: the Atherosclerosis Risk in Communities studyPamela L Lutsey
Division of Epidemiology and Community Health, University of Minnesota, School of Public Health, Minneapolis, USA
Circulation 117:754-61. 2008The role of diet in the origin of metabolic syndrome (MetSyn) is not well understood; thus, we sought to evaluate the relationship between incident MetSyn and dietary intake using prospective data from 9514 participants (age, 45 to 64 ..
- Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidanceMarjorie L McCullough
American Cancer Society, Atlanta, GA 30329, USA
Am J Clin Nutr 76:1261-71. 2002..Research suggests that greater reductions in risk are possible with more specific guidance...
- Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequencyAngela M Hancock
Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA
Proc Natl Acad Sci U S A 107:8924-30. 2010..This provides genome-wide evidence for selection due to changes in ecoregion, diet, and subsistence...
- Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1Gizem Rizki
Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
J Lipid Res 47:2280-90. 2006..MCD feeding also induces hepatic steatosis, by an independent mechanism. Viewed together, these two disparate consequences of MCD feeding (weight loss and hepatic steatosis) give the appearance of an unusual form of lipodystrophy...
- Fiber and magnesium intake and incidence of type 2 diabetes: a prospective study and meta-analysisMatthias B Schulze
Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
Arch Intern Med 167:956-65. 2007..We examined associations between fiber and magnesium intake and risk of type 2 diabetes and summarized existing prospective studies by meta-analysis...
- Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesityDouglas Osei-Hyiaman
National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, Maryland 20892, USA
J Clin Invest 115:1298-305. 2005..CB(1) (-/-) mice are resistant to diet-induced obesity even though their caloric intake is similar to that of wild-type mice, suggesting that ..
- MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesityAndre Kleinridders
Department of Mouse Genetics and Metabolism, Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases CECAD and Center of Molecular Medicine Cologne CMMC, University of Cologne, D 50674 Cologne, Germany
Cell Metab 10:249-59. 2009..To determine the functional significance of TLR signaling in the CNS in the development of leptin resistance and diet-induced obesity in vivo, we have characterized mice deficient for the TLR adaptor molecule MyD88 in the CNS (MyD88(..
- Interventions to prevent obesity in 0-5 year olds: an updated systematic review of the literatureKylie D Hesketh
Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Victoria, Australia
Obesity (Silver Spring) 18:S27-35. 2010..Inclusion criteria: interventions reporting child anthropometric, diet, physical activity, or sedentary behavior outcomes and focusing on children aged 0-5 years of age...
- Diet, nutrition and the prevention of excess weight gain and obesityB A Swinburn
Physical Activity and Nutrition Research Unit, School of Health Sciences, Deakin University, Melbourne, Australia
Public Health Nutr 7:123-46. 2004To review the evidence on the diet and nutrition causes of obesity and to recommend strategies to reduce obesity prevalence.
- Diet and cancer prevention: Contributions from the European Prospective Investigation into Cancer and Nutrition (EPIC) studyCarlos A Gonzalez
Unit of Nutrition, Environment and Cancer, Programme of Epidemilogical Cancer Research, Institut Catala d Oncologia, Av Gran Via S N, Km 2 7, 08907 L Hospitalet, Barcelona, Spain
Eur J Cancer 46:2555-62. 2010..We present the main findings observed to date from the European Prospective Investigation into Cancer and Nutrition (EPIC) on dietary factors associated with the most frequent cancer sites...
- A central role for JNK in obesity and insulin resistanceJiro Hirosumi
Division of Biological Sciences and Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, USA
Nature 420:333-6. 2002..Thus, JNK is a crucial mediator of obesity and insulin resistance and a potential target for therapeutics...
- A long-term high-protein diet markedly reduces adipose tissue without major side effects in Wistar male ratsMagali Lacroix
Unité INRA 914 Physiologie de la Nutrition et Comportement Alimentaire, INA PG, 16 rue Claude Bernard, 75231 Paris Cedex 05, France
Am J Physiol Regul Integr Comp Physiol 287:R934-42. 2004..However, the long-term effects of a high-protein diet on a broad range of parameters have not been investigated...
- Amino-acid imbalance explains extension of lifespan by dietary restriction in DrosophilaRichard C Grandison
Institute of Healthy Ageing, Department of Genetics Evolution and Environment, University College London, UK
Nature 462:1061-4. 2009..In other organisms, including mammals, it may be possible to obtain the benefits to lifespan of dietary restriction without incurring a reduction in fecundity, through a suitable balance of nutrients in the diet.
- Study design, exposure variables, and socioeconomic determinants of participation in Diet, Cancer and Health: a population-based prospective cohort study of 57,053 men and women in DenmarkAnne Tjønneland
Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen, Denmark
Scand J Public Health 35:432-41. 2007b>Diet is considered an important aspect of lifestyle related to cancer development. To contribute further knowledge within this field a Danish prospective cohort study "Diet, Cancer and Health" has been initiated...
- How host-microbial interactions shape the nutrient environment of the mammalian intestineLora V Hooper
Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Annu Rev Nutr 22:283-307. 2002..These and other studies underscore the importance of understanding precisely how nutrient metabolism serves to establish and sustain symbiotic relationships between mammals and their bacterial partners...
- Randomized trial of a behavioral intervention to prevent excessive gestational weight gain: the Fit for Delivery StudySuzanne Phelan
Departments of Kinesiology, California Polytechnic State University, San Luis Obispo, 93407 0386, USA
Am J Clin Nutr 93:772-9. 2011....
- Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of ageCarlos A Camargo
Center for D receptor Activation Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Am J Clin Nutr 85:788-95. 2007..Vitamin D deficiency and asthma are common at higher latitudes. Although vitamin D has important immunologic effects, its relation with asthma is unknown...
- Folate and colorectal cancer: an evidence-based critical reviewYoung In Kim
Department of Medicine and Nutritional Sciences, Medical Sciences Building, University of Toronto, 1 King s College Circle, Toronto, Ontario, Canada
Mol Nutr Food Res 51:267-92. 2007..Based on the lack of compelling supportive evidence and on the potential tumor-promoting effect, routine folic acid supplementation should not be recommended as a chemopreventive measure against CRC at present...
- Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesisHerbert Tilg
Christian Doppler Research Laboratory for Gut Inflammation, Medical University Innsbruck, Innsbruck, Austria
Hepatology 52:1836-46. 2010..Endoplasmic reticulum stress and related signaling networks, (adipo)cytokines, and innate immunity are emerging as central pathways that regulate key features of NASH...
- Diet, gut microbiota and immune responsesKendle M Maslowski
Garvan Institute of Medical Research, and the Cooperative Research Centre for Asthma and Airways, Sydney, Australia
Nat Immunol 12:5-9. 2011The fields of immunology, microbiology, nutrition and metabolism are rapidly converging. Here we expand on a diet-microbiota model as the basis for the greater incidence of asthma and autoimmunity in developed countries.
- Comparison of demography, diet, lifestyle, and serum lipid levels between the Guangxi Bai Ku Yao and Han populationsYin Ruixing
Department of Cardiology, Institute of Cardiovascular Diseases, First Affiliated Hospital, Guangxi Medical University, Nanning 530021, Guangxi, People s Republic of China
J Lipid Res 48:2673-81. 2007..The aim of this study was to compare the effects of demography, diet, and lifestyle on serum lipid levels between the Bai Ku Yao and Han populations...
- Brown fat and the myth of diet-induced thermogenesisLeslie P Kozak
Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
Cell Metab 11:263-7. 2010..Studies in obese rats and mice lacking UCP1 indicate that diet-induced thermogenesis by BAT is unlikely.
- Maternal vitamin D status determines bone variables in the newbornH T Viljakainen
Department of Applied Chemistry and Microbiology, Division of Nutrition, P O Box 66, University of Helsinki, FI 00014 Helsinki, Finland
J Clin Endocrinol Metab 95:1749-57. 2010..Maternal vitamin D status may program neonatal skeletal development. The objective here was to determine the association of mothers' vitamin D status with bone variables of their newborns...
- Obesity and risk of type 2 diabetes and cardiovascular disease in children and adolescentsMichael I Goran
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
J Clin Endocrinol Metab 88:1417-27. 2003..Therefore, the purpose of this paper is to review the pathophysiology of type 2 diabetes and cardiovascular risk in obese children and adolescents...
- Causes of cancer in the world: comparative risk assessment of nine behavioural and environmental risk factorsGoodarz Danaei
Harvard School of Public Health, Boston, MA 02115, USA
Lancet 366:1784-93. 2005..In this report, we estimate mortality from 12 types of cancer attributable to nine risk factors in seven World Bank regions for 2001...
- Preventing excessive weight gain during pregnancy - a controlled trial in primary health careT I Kinnunen
UKK Institute for Health Promotion Research, Tampere, Finland
Eur J Clin Nutr 61:884-91. 2007To investigate whether individual counselling on diet and physical activity during pregnancy can have positive effects on diet and leisure time physical activity (LTPA) and prevent excessive gestational weight gain.
- Diet, physical activity, and sedentary behaviors as risk factors for overweight in adolescenceKevin Patrick
University of California, San Diego, San Diego State University, and Kaiser Permanente Medical Group, San Diego, CA 92093 0811, USA
Arch Pediatr Adolesc Med 158:385-90. 2004..The proportion of overweight adolescents has increased, but the behavioral risk factors for overweight youth are not well understood...
- The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic micePeter J Turnbaugh
Center for Genome Sciences, Washington University School of Medicine, St Louis, MO 63108, USA
Sci Transl Med 1:6ra14. 2009b>Diet and nutritional status are among the most important modifiable determinants of human health. The nutritional value of food is influenced in part by a person's gut microbial community (microbiota) and its component genes (microbiome)...
- Sirt1 protects against high-fat diet-induced metabolic damagePaul T Pfluger
Department of Psychiatry, Obesity Research Center, Genome Research Institute, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA
Proc Natl Acad Sci U S A 105:9793-8. 2008..Mammalian Sirt1 is a protein deacetylase that has been involved in resveratrol-mediated protection from high-fat diet-induced metabolic damage, but direct proof for the implication of Sirt1 has remained elusive...
- Does social class predict diet quality?Nicole Darmon
INRA, UMR1260, Nutriments Lipidiques et Prévention des Maladies Métaboliques, Marseille, France
Am J Clin Nutr 87:1107-17. 2008A large body of epidemiologic data show that diet quality follows a socioeconomic gradient...
- Diet-induced insulin resistance in mice lacking adiponectin/ACRP30Norikazu Maeda
Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University, Osaka, Japan
Nat Med 8:731-7. 2002..The KO mice exhibited severe diet-induced insulin resistance with reduced insulin-receptor substrate 1 (IRS-1)-associated phosphatidylinositol 3 ..
- Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanismsYiying Zhang
Department of Pediatrics, Division of Molecular Genetics, Columbia University, New York, NY 10032, USA
Diabetes 56:1647-54. 2007..leucine intake via leucine-containing drinking water in mice with free excess to either a rodent chow or a high-fat diet (HFD)...
- Linking long-term dietary patterns with gut microbial enterotypesGary D Wu
Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Science 334:105-8. 2011b>Diet strongly affects human health, partly by modulating gut microbiome composition. We used diet inventories and 16S rDNA sequencing to characterize fecal samples from 98 individuals...
- Intensive lifestyle changes for reversal of coronary heart diseaseD Ornish
Department of Medicine, California Pacific Medical Center, San Francisco, USA
JAMA 280:2001-7. 1998..The Lifestyle Heart Trial demonstrated that intensive lifestyle changes may lead to regression of coronary atherosclerosis after 1 year...
- Does chocolate reduce blood pressure? A meta-analysisKarin Ried
Discipline of General Practice, The University of Adelaide, Adelaide, SA 5005, Australia
BMC Med 8:39. 2010..Recently, several additional trials have been conducted with conflicting results. Our study summarises current evidence on the effect of flavanol-rich cocoa products on blood pressure in hypertensive and normotensive individuals...
- Effects of comprehensive lifestyle modification on blood pressure control: main results of the PREMIER clinical trialLawrence J Appel
Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Md 21205 2233, USA
JAMA 289:2083-93. 2003..The Dietary Approaches to Stop Hypertension (DASH) diet also lowers BP...
- Optimal diets for prevention of coronary heart diseaseFrank B Hu
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
JAMA 288:2569-78. 2002..Thus, identification of the dietary changes that most effectively prevent CHD is critical...
- Sodium in the Finnish diet: 20-year trends in urinary sodium excretion among the adult populationT Laatikainen
Department of Epidemiology and Health Promotion, National Public Health Institute KTL, Helsinki, Finland
Eur J Clin Nutr 60:965-70. 2006..In Finland, cross-sectional population surveys to monitor cardiovascular risk factors have been carried out since the 1970s. The main aim of this paper is to present trends in urinary sodium and potassium excretion from 1979 to 2002...
- Total dietary carbohydrate, sugar, starch and fibre intakes in the European Prospective Investigation into Cancer and NutritionA E Cust
Dietary Exposure Assessment Group, International Agency for Research on Cancer, Lyon, France
Eur J Clin Nutr 63:S37-60. 2009..To describe dietary carbohydrate intakes and their food sources among 27 centres in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study...
- Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2David B Savage
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA
J Clin Invest 116:817-24. 2006..We used a diet-induced rat model of nonalcoholic fatty liver disease (NAFLD) and hepatic insulin resistance to explore the impact ..
- Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunctionWai Mun Loke
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
Arterioscler Thromb Vasc Biol 30:749-57. 2010....
- Stable isotope evidence for increasing dietary breadth in the European mid-Upper PaleolithicM P Richards
Department of Archaeological Science, University of Bradford, Bradford, West Yorkshire, BD7 1DP, United Kingdom
Proc Natl Acad Sci U S A 98:6528-32. 2001....
- Non-Human Primate Model of Gluten-Sensitive EnteropathyKarol Sestak; Fiscal Year: 2010..to celiac disease (CD), and in rhesus monkeys as well as in humans it can be induced by a gluten-containing diet. We recently performed experiments where gluten-sensitive and control macaques were fed gluten- containing diets ..
- Non-Human Primate Model of Gluten-Sensitive EnteropathyKarol Sestak; Fiscal Year: 2009..to celiac disease (CD), and in rhesus monkeys as well as in humans it can be induced by a gluten-containing diet. We recently performed experiments where gluten-sensitive and control macaques were fed gluten- containing diets ..
- SPECIES DIFFERENCE IN THE BIOTRANSFORMATION OF AFLATOXINDavid Eaton; Fiscal Year: 2003Numerous studies have demonstrated that biologically active, natural components of the diet may confer resistance to chemical carcinogens via induction and/or inhibition of biotransformation enzymes...
- BRAIN GLUCOSENSING NEURONS IN HEALTH AND DIABETESBarry E Levin; Fiscal Year: 2010..However, rats selectively bred to develop diet-induced obesity (DIO) on a 31% fat, high sucrose, high energy (HE) diet have an inborn elevation of ARC GK in ..
- Television Advertising and Children's Diet Activity and Obesity PrevalenceLisa Powell; Fiscal Year: 2010Poor diet, inactivity and obesity have been linked to increased risks for a number of chronic diseases including cancer and cardiovascular diseases...
- The Role of Adenosine in Ketogenic Diet TherapySUSAN A contact MASINO; Fiscal Year: 2010..As an alternative, therapy with a high-fat low-carbohydrate (ketogenic) diet can be highly effective in medically-refractory epilepsy, and the mechanisms underlying its success can offer ..
- Diet and Gastrointestinal Cancer Risk in African Americans and Rural AfricansSTEPHEN JD O apos KEEFE; Fiscal Year: 2010Geographical variations in cancer incidence can be attributed to environmental causes in general, and to diet, in particular...
- Cholecystokinin - Role in postprandial gastric motilityHelen E Raybould; Fiscal Year: 2010..are sensed in the gut, the neural pathways activated, and how these may be altered by long term changes in diet leading to increased food intake and obesity...
- EFFECT OF CHRONIC AMYLOSE FEEDING IN ADIPOSITYDANIEL BESSESSEN; Fiscal Year: 2001..The specific aims are: 1) to define the dose-response relationship between the amylose content of the diet and postprandial glycemic/insulinemic response; 2) to measure adipocyte cell size and number in response to a high ..
- Omega-3 fat to reduce risk for breast cancerWANDA ELAINE HARDMAN; Fiscal Year: 2010..The results of epidemiology studies indicate that diet has a profound influence on breast cancer risk...
- Omega-3 fat to reduce risk for breast cancerWANDA HARDMAN; Fiscal Year: 2009..The results of epidemiology studies indicate that diet has a profound influence on breast cancer risk...
- Omega 3 fatty acids to reduce risk for breast cancerWANDA HARDMAN; Fiscal Year: 2007..The results of epidemiology studies indicate that diet has a profound influence on breast cancer risk...
- A Mediterranean Diet in for Colon Cancer PreventionZora Djuric; Fiscal Year: 2009A Mediterranean Diet for Colon Cancer Prevention: Epidemiological and animal studies indicate that the major components of the traditional Cretan-Mediterranean diet have great promise for the prevention of colorectal cancer while ..
- HUMAN REQUIREMENTS FOR THE NUTRIENT CHOLINESteven Zeisel; Fiscal Year: 2004..the structural integrity and signaling functions of cell membranes; it is the major source of methyl-groups in the diet, and it directly affects cholinergic neurotransmission, transmembrane signaling and lipid transport/metabolism...
- Economic Contextual Influences on Population Diet and ObesityLisa Powell; Fiscal Year: 2010Poor diet and obesity have been linked to increased risks for a number of chronic diseases including cancer and cardiovascular diseases...
- Economic Contextual Influences on Population Diet and ObesityLisa Powell; Fiscal Year: 2009Poor diet and obesity have been linked to increased risks for a number of chronic diseases including cancer and cardiovascular diseases...
- DIETARY COMPOSITION, OBESITY, AND CARDIOVASCULAR RISKERNST SCHAEFER; Fiscal Year: 2003..for low density lipoprotein (LDL) lowering and CHD risk reduction, but there controversy about other aspects of the diet. We propose to examine the effects of three diets meeting National Cholesterol Education program Step 2 diet ..
- T Cells, Macrophages, Chemokines, and Adiposopathy in Diet-Induced ObesityChristie M Ballantyne; Fiscal Year: 2010..Using a mouse model of obesity induced by a high-fat (HF) diet rich in saturated fatty acids (SFAs), we made the novel finding that T cells are increased and the chemokine ..
- Experimental analysis of price changes and food purchases in obese and lean motheLeonard H Epstein; Fiscal Year: 2010..value of food (RRV) and impulsivity moderate the effects of prices on energy and macronutrients purchased and diet quality in a large sample of 225 ethnically and economically diverse adults...
- RCT of the Naturopathic Anti-inflammatory DietPatricia Elmer; Fiscal Year: 2007..The "anti-inflammatory"(AI) diet is frequently used and recommended to treat a variety of conditions classified by naturopathic physicians as "..
- Intestinal Microbiota, Diet and Risk of Colorectal AdenomasRobert S Sandler; Fiscal Year: 2010..Potential mechanisms for the link between gut microbiota and CRC is through diet and inflammation...
- Intestinal Microbiota, Diet and Risk of Colorectal AdenomasTemitope Keku; Fiscal Year: 2009..Potential mechanisms for the link between gut microbiota and CRC is through diet and inflammation...