histological techniques

Summary

Top Publications

  1. pmc An intronic LINE-1 element insertion in the dystrophin gene aborts dystrophin expression and results in Duchenne-like muscular dystrophy in the corgi breed
    Bruce F Smith
    Scott Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
    Lab Invest 91:216-31. 2011
  2. ncbi Tissue microarray of head and neck squamous carcinoma: validation of the methodology for the study of cutaneous fatty acid-binding protein, vascular endothelial growth factor, involucrin and Ki-67
    Wafaey Gomaa
    Department of Pathology, University of Liverpool, Duncan Building, Daulby Street, Liverpool, L69 3GA, UK
    Virchows Arch 447:701-9. 2005
  3. pmc Diffusion and imaging properties of three new lipophilic tracers, NeuroVue Maroon, NeuroVue Red and NeuroVue Green and their use for double and triple labeling of neuronal profile
    B Fritzsch
    Department of Biomedical Sciences, Creighton University, Omaha, NE 68178, USA
    Brain Res Bull 66:249-58. 2005
  4. ncbi Amplification of tissue by construction of tissue microarrays
    D L Rimm
    Department of Pathology and the Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Exp Mol Pathol 70:255-64. 2001
  5. ncbi Nodavirus infections in Israeli mariculture
    M Ucko
    Israel Oceanographic and Limnological Research Ltd, National Center for Mariculture, Eilat, Israel
    J Fish Dis 27:459-69. 2004
  6. ncbi Proliferative renal myxosporidiosis in spawning coho salmon (Oncorhynchus kisutch) in British Columbia and Washington
    Simon Jones
    Department of Fisheries and Oceans, Pacific Biological Station, 3190 Hammond Bay Road, Nanaimo, British Columbia, V9T 6N7, Canada
    Folia Parasitol (Praha) 51:221-7. 2004
  7. ncbi Sequential pathology after initial freshwater bath treatment for amoebic gill disease in cultured Atlantic salmon, Salmo salar L
    M B Adams
    School of Aquaculture, Aquafin CRC, Tasmanian Aquaculture and Fisheries Institute, Launceston, Tasmania, Australia
    J Fish Dis 27:163-73. 2004
  8. ncbi Identification of a serine protease gene expressed by Myxobolus cerebralis during development in rainbow trout Oncorhynchus mykiss
    Garry O Kelley
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, USA
    Dis Aquat Organ 59:235-48. 2004
  9. ncbi Effects of the gill monogenean Zeuxapta seriolae (Meserve, 1938) and treatment with hydrogen peroxide on pathophysiology of kingfish, Seriola lalandi Valenciennes, 1833
    B Mansell
    Tasmanian Aquaculture and Fisheries Institute, School of Aquaculture, University of Tasmania, Launceston, Tasmania, Australia
    J Fish Dis 28:253-62. 2005
  10. ncbi Lernanthropus kroyeri infections in farmed sea bass Dicentrarchus labrax: pathological features
    Maurizio Manera
    Department of Food Science, University of Teramo, Piazza Aldo Moro, 45, 64100 Teramo, Italy
    Dis Aquat Organ 57:177-80. 2003

Research Grants

Detail Information

Publications222 found, 100 shown here

  1. pmc An intronic LINE-1 element insertion in the dystrophin gene aborts dystrophin expression and results in Duchenne-like muscular dystrophy in the corgi breed
    Bruce F Smith
    Scott Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
    Lab Invest 91:216-31. 2011
    ..Affected puppies had a normal birth weight but they experienced a striking growth delay in the first 5 days. In summary, the new corgi DMD model offers an excellent opportunity to study DMD pathogenesis and to develop novel therapies...
  2. ncbi Tissue microarray of head and neck squamous carcinoma: validation of the methodology for the study of cutaneous fatty acid-binding protein, vascular endothelial growth factor, involucrin and Ki-67
    Wafaey Gomaa
    Department of Pathology, University of Liverpool, Duncan Building, Daulby Street, Liverpool, L69 3GA, UK
    Virchows Arch 447:701-9. 2005
    ..Concordance with whole-tissue section data is reassuring, but data from microarrays need to be validated against clinical outcomes...
  3. pmc Diffusion and imaging properties of three new lipophilic tracers, NeuroVue Maroon, NeuroVue Red and NeuroVue Green and their use for double and triple labeling of neuronal profile
    B Fritzsch
    Department of Biomedical Sciences, Creighton University, Omaha, NE 68178, USA
    Brain Res Bull 66:249-58. 2005
    ..Double labeling experiments using NeuroVue Red and eGFP allowed us to demonstrate that every fiber in the neonatal ear is surrounded by developing Schwann cells...
  4. ncbi Amplification of tissue by construction of tissue microarrays
    D L Rimm
    Department of Pathology and the Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Exp Mol Pathol 70:255-64. 2001
    ..It has the potential for allowing validation of new genes at a speed comparable to the rapid rate of gene discovery afforded by DNA microarrays...
  5. ncbi Nodavirus infections in Israeli mariculture
    M Ucko
    Israel Oceanographic and Limnological Research Ltd, National Center for Mariculture, Eilat, Israel
    J Fish Dis 27:459-69. 2004
    ..Red Sea and Mediterranean isolated sequences grouped in distinct clusters, together with several foreign isolates from the Mediterranean area and the Far East, as phylogenetically close to the Epinephelus akaara RGNNV type...
  6. ncbi Proliferative renal myxosporidiosis in spawning coho salmon (Oncorhynchus kisutch) in British Columbia and Washington
    Simon Jones
    Department of Fisheries and Oceans, Pacific Biological Station, 3190 Hammond Bay Road, Nanaimo, British Columbia, V9T 6N7, Canada
    Folia Parasitol (Praha) 51:221-7. 2004
    ..oncorhynchi and Myxidium lieberkuehni. CKX is hypothesised to be the abortive extrasporogonic development of a Sphaerospora sp. or Myxidium sp. occurring in immune-incompetent spawning and senescent salmon...
  7. ncbi Sequential pathology after initial freshwater bath treatment for amoebic gill disease in cultured Atlantic salmon, Salmo salar L
    M B Adams
    School of Aquaculture, Aquafin CRC, Tasmanian Aquaculture and Fisheries Institute, Launceston, Tasmania, Australia
    J Fish Dis 27:163-73. 2004
    ..was noted. We conclude that pathogenesis during the inter-bath period was identical to initial infection although the source of re-infection remains to be established...
  8. ncbi Identification of a serine protease gene expressed by Myxobolus cerebralis during development in rainbow trout Oncorhynchus mykiss
    Garry O Kelley
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, USA
    Dis Aquat Organ 59:235-48. 2004
    ..Identifying genes encoding these enzymes and characterization of their functions can lead to the development of new chemotherapeutic protocols and vaccine approaches to control parasitic diseases...
  9. ncbi Effects of the gill monogenean Zeuxapta seriolae (Meserve, 1938) and treatment with hydrogen peroxide on pathophysiology of kingfish, Seriola lalandi Valenciennes, 1833
    B Mansell
    Tasmanian Aquaculture and Fisheries Institute, School of Aquaculture, University of Tasmania, Launceston, Tasmania, Australia
    J Fish Dis 28:253-62. 2005
    ..g. lactate, osmolality) and extent of the effects (e.g. haemoglobin) was much less than that caused by chronic infection with Z. seriolae...
  10. ncbi Lernanthropus kroyeri infections in farmed sea bass Dicentrarchus labrax: pathological features
    Maurizio Manera
    Department of Food Science, University of Teramo, Piazza Aldo Moro, 45, 64100 Teramo, Italy
    Dis Aquat Organ 57:177-80. 2003
    ..Parasitism by L. kroyeri affected the host's condition factor (mean +/- SE in uninfected vs parasitized; 1.88 +/- 0.04 vs 1.66 +/- 0.12; p < 0.05)...
  11. ncbi heart of glass regulates the concentric growth of the heart in zebrafish
    John D Mably
    Cardiovascular Research Center, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA
    Curr Biol 13:2138-47. 2003
    ..In heart of glass mutant embryos, the number of cells in the myocardium is normal, but they are not added in the concentric direction. As a consequence, the chambers are huge and dysfunctional, and the myocardium remains a single layer...
  12. ncbi Zebrafish periostin is required for the adhesion of muscle fiber bundles to the myoseptum and for the differentiation of muscle fibers
    Hisaaki Kudo
    Department of Biological Information, Tokyo Institute of Technology, Yokohama 226 8501, Japan
    Dev Biol 267:473-87. 2004
    ....
  13. ncbi Groucho homologue Grg5 interacts with the transcription factor Runx2-Cbfa1 and modulates its activity during postnatal growth in mice
    WenFang Wang
    Department of Oral and Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02215, USA
    Dev Biol 270:364-81. 2004
    ..We therefore conclude that Grg5 enhances Runx2 activity in vivo...
  14. ncbi Development of a cost-effective oral vaccination method against viral disease in fish
    A R Companjen
    Wageningen University and Research Centre Department of Animal Sciences, Cell Biology and Immunology Group, The Netherlands
    Dev Biol (Basel) 121:143-50. 2005
    ..The results further indicated that a specific humoral immune response was evoked...
  15. ncbi Important disease conditions of newly cultured species in intensive freshwater farms in Greece: first incidence of nodavirus infection in Acipenser sp
    F Athanassopoulou
    Laboratory of Ichthyology, Fish Diseases and Aquaculture, Faculty of Veterinary Medicine, School of Health Sciences, University of Thessaly, Karditsa, Greece
    Dis Aquat Organ 60:247-52. 2004
    ..and Myxobacteria spp. Tilapia were very susceptible to gas bubble disease and A. hydrophila. This bacterium was associated with management manipulations for all species and fully responsive to corrective hygiene methods...
  16. ncbi The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm
    Lei Zhao
    Center for Experimental Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6160, USA
    Nat Med 10:966-73. 2004
    ..These data link the 5-LO pathway to hyperlipidemia-dependent inflammation of the arterial wall and to pathogenesis of aortic aneurysms through a potential chemokine intermediary route...
  17. ncbi Intracellular infection with Spironucleus barkhanus (Diplomonadida: Hexamitidae) in farmed Arctic char Salvelinus alpinus
    Erik Sterud
    National Veterinary Institute, PO Box 8156 Dep, 0033 Oslo, Norway
    Dis Aquat Organ 56:155-61. 2003
    ..The relatively few gross and histopathological lesions may indicate that Arctic char are more tolerant to this parasite than Atlantic salmon...
  18. ncbi Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway
    Reiko Hanada
    Molecular Genetics, Institute of Life Science, Kurume University, Kurume, Fukuoka 839 0861, Japan
    Nat Med 10:1067-73. 2004
    ..These characteristic functions of NMU may provide new insight for understanding the pathophysiological basis of obesity...
  19. ncbi Immunohistochemistry, histopathology and ultrastructure of Gasterosteus aculeatus tissues infected with Glugea anomala
    B S Dezfuli
    Department of Biology, University of Ferrara, Via Borsari, 46, 44100 Ferrara, Italy
    Dis Aquat Organ 58:193-202. 2004
    ..Specifically, the protozoan induces a response in the stickleback nervous system, the reaction of which is revealed through the application of immunohistochemical techniques...
  20. ncbi Acute and persistent experimental nodavirus infection in spotted wolffish Anarhichas minor
    R Johansen
    National Veterinary Institute, PO Box 8156, 0033 Oslo, Norway
    Dis Aquat Organ 57:35-41. 2003
    ..Nodavirus was reisolated from fish at the last sampling in SSN-1 cells, showing that nodavirus retains virulence in persistently infected wolffish for at least 16 wk post-bath-challenge...
  21. ncbi A microsporidian parasite of the genus Spraguea in the nervous tissues of the Japanese anglerfish Lophius litulon
    Mark A Freeman
    Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1 1 1, Bunkyo, Tokyo 113 8657, Japan
    Folia Parasitol (Praha) 51:167-76. 2004
    ..This report of Spraguea americana is the first report of a Spraguea species from L. litulon and indeed from the Pacific water mass...
  22. ncbi X-cells in fish pseudotumors are parasitic protozoans
    Satoshi Miwa
    Inland Station, National Research Institute of Aquaculture, Tamaki, Mie 519 0423, Japan
    Dis Aquat Organ 58:165-70. 2004
    ..On the other hand, a probe specific for vertebrate 18S rRNA hybridized with the host-fish cells, but not with X-cells. This is conclusive evidence that X-cells are parasitic protozoans...
  23. ncbi The anterior-posterior axis emerges respecting the morphology of the mouse embryo that changes and aligns with the uterus before gastrulation
    Daniel Mesnard
    Wellcome Trust Cancer Research Gurdon Institute, Tennis Court Road, Cambridge CB2 1QR, United Kingdom
    Curr Biol 14:184-96. 2004
    ..When the anterior-posterior axis of the mouse embryo becomes explicit at gastrulation, it is almost perpendicular to the long uterine axis. This led to the belief that the uterus could play a key role in positioning this future body axis...
  24. ncbi Rapid evolution of muscle fibre number in post-glacial populations of Arctic charr Salvelinus alpinus
    Ian A Johnston
    Gatty Marine Laboratory, School of Biology, University of St Andrews, St Andrews, Fife, KY16 8LB, Scotland, UK
    J Exp Biol 207:4343-60. 2004
    ..The predictions of the optimal fibre size hypothesis and its consequences for the adaptive evolution of muscle architecture in fishes are briefly discussed...
  25. ncbi Changes in the innate immune response of Atlantic salmon, Salmo salar L., exposed to experimental infection with Neoparamoeba sp
    K A Gross
    Tasmanian Aquaculture and Fisheries Institute and Aquafin CRC, School of Aquaculture, University of Tasmania, Launceston, Tasmania, Australia
    J Fish Dis 28:293-9. 2005
    ..There was an increase in the chemotactic response of anterior kidney macrophages isolated from exposed fish relative to control fish at 8 dpe. Total protein and lysozyme levels were not affected by Neoparamoeba sp. exposure...
  26. ncbi Gross pathology and its relationship with histopathology of amoebic gill disease (AGD) in farmed Atlantic salmon, Salmo salar L
    M B Adams
    School of Aquaculture, Aquafin CRC, Tasmanian Aquaculture and Fisheries Institute, Launceston, Tasmania, Australia
    J Fish Dis 27:151-61. 2004
    ..It was concluded that clinical diagnosis is acceptable as a farm-monitoring tool only. Removal of grossly affected tissue and subsequent histological examination is recommended to improve diagnostic accuracy...
  27. ncbi A parasite survey of farmed Southern bluefin tuna, Thunnus maccoyii (Castelnau)
    M R Deveney
    PIRSA Aquaculture, Primary Industries and Resources South Australia and Aquafin CRC, Adelaide, SA 5001, Australia
    J Fish Dis 28:279-84. 2005
    ..Targeted screening for U. nigricans exposed a low prevalence, most probably due to a lack of sensitivity in the test method. Few of the parasites examined pose a risk to the health of farmed SBT...
  28. ncbi Control of Salmincola californiensis (Copepoda: Lernaeapodidae) in rainbow trout, Oncorhynchus mykiss (Walbaum): a clinical and histopathological study
    R J Roberts
    University of Idaho, Center for Sustainable Aquaculture, Hagerman Fish Culture Experiment Station, Hagerman, ID 83332, USA
    J Fish Dis 27:73-9. 2004
    ..The use of oral dosage with ivermectin is an effective treatment for S. californiensis and could be particularly beneficial for use with endangered salmon broodstocks infested with the parasite...
  29. ncbi Cryptosporidium scophthalmi n. sp. (Apicomplexa: Cryptosporidiidae) from cultured turbot Scophthalmus maximus. Light and electron microscope description and histopathological study
    P Alvarez-Pellitero
    Instituto de Acuicultura Torre de la Sal, Consejo Superior de Investigaciones Cientificas, Ribera de Cabanes, 12595 Castellon, Spain
    Dis Aquat Organ 62:133-45. 2004
    ..An inflammatory reaction involving leucocyte infiltration was sometimes observed...
  30. ncbi Pseudocohnilembus persalinus (Ciliophora: Scuticociitida) is an additional species causing scuticociliatosis in olive flounder Paralichthys olivaceus
    Sung Mi Kim
    Department of Aquatic Life Medicine, Pukyong National University, Pusan 608 737, Korea
    Dis Aquat Organ 62:239-44. 2004
    ..These data suggest that the multiplex PCR procedure would make it possible to avoid the cumbersome and time-consuming procedures of morphological analysis for the definitive identification of ciliates...
  31. ncbi Introduction and comparison of two methods of assessment of coronary lesions in Atlantic salmon, Salmo salar L
    S L Seierstad
    Department of Basic Sciences and Aquatic Medicine, Norwegian School of Veterinary Science, Oslo, Norway
    J Fish Dis 28:189-97. 2005
    ..5%. The semi-quantitative method was a valid and reliable method for coronary lesion evaluation in Atlantic salmon...
  32. ncbi Occurrence of scuticociliatosis in olive flounder Paralichthys olivaceus by Phiasterides dicentrarchi (Ciliophora: scuticociliatida)
    Sung Mi Kim
    Department of Aquatic Life Medicine, Pukyong National University, Pusan 608 737, Korea
    Dis Aquat Organ 62:233-8. 2004
    ..dicentrarchi, and sequenced the SS rRNA gene in order to design P. dicentrarchi specific primers. This is the first report on scuticociliatosis caused by P. dicentrarchi from marine fish in Asia...
  33. ncbi Evolution of OTP-independent larval skeleton patterning in the direct-developing sea urchin, Heliocidaris erythrogramma
    Na Zhou
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    J Exp Zool B Mol Dev Evol 300:58-71. 2003
    ..erythrogramma. OTP plays an important role in patterning the larval skeleton of H. tuberculata, but this role apparently has been lost in the evolution of the H. erythrogramma larva, and replaced by a new patterning mechanism...
  34. pmc The role of Axin2 in calvarial morphogenesis and craniosynostosis
    Hsiao Man Ivy Yu
    Center for Oral Biology, Department of Biomedical Genetics, Abs Institute of Biomedical Sciences, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Development 132:1995-2005. 2005
    ..The craniofacial anomalies caused by the Axin2 mutation are mediated through activation of beta-catenin signaling, suggesting a novel role for the Wnt pathway in skull morphogenesis...
  35. ncbi Regulation of neuroD2 expression in mouse brain
    Chin Hsing Lin
    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Dev Biol 265:234-45. 2004
    ....
  36. ncbi Loss of AP-2alpha impacts multiple aspects of ventral body wall development and closure
    Stephanie Brewer
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA
    Dev Biol 267:399-417. 2004
    ..These findings provide a fundamental understanding of how AP-2alpha functions in the closure of the ventral body wall, as well as offer insight into related human birth defects...
  37. ncbi Loss of connexin 26 in mammary epithelium during early but not during late pregnancy results in unscheduled apoptosis and impaired development
    Celine Bry
    Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Dev Biol 267:418-29. 2004
    ..Cx26 is considered a tumor suppressor gene and Cx26-null mammary tissue was evaluated after five pregnancies. No hyperproliferation or hyperplasia was observed, suggesting that Cx26 does not function as a tumor suppressor...
  38. pmc Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants
    Luke T Krebs
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Genes Dev 18:2469-73. 2004
    ..These results demonstrate that vascular remodeling in the mouse embryo is sensitive to Dll4 gene dosage and that Notch activation in endothelial cells is essential for embryonic vascular remodeling...
  39. ncbi Development of the mammalian urethra is controlled by Fgfr2-IIIb
    Anita Petiot
    Cancer Research UK, Lincoln s Inn Fields, London WC2A 3PX, UK
    Development 132:2441-50. 2005
    ..This represents the first example of how the developing genitourinary system integrates cues from systemically circulating steroid hormones with a locally expressed growth factor pathway...
  40. ncbi Characteristic defects in neural crest cell-specific Galphaq/Galpha11- and Galpha12/Galpha13-deficient mice
    Dagmara A Dettlaff-Swiercz
    Institute of Pharmacology, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany
    Dev Biol 282:174-82. 2005
    ..In contrast, ET-3/ET(B)-mediated development of neural crest-derived melanocytes and enteric neurons appears to involve G-proteins different from G(q)/G(11)/G(12)/G(13)...
  41. ncbi Gonadal structure of the serial-sex changing gobiid fish Trimma okinawae
    Yasuhisa Kobayashi
    Sesoko Station, Tropical Biosphere Research Center, University of the Ryukyus, 3422 Sesoko, Motobu cho, Okinawa 905 0227, Japan
    Dev Growth Differ 47:7-13. 2005
    ..In the testis, moderate immunopositive signals were obtained from dual-phase male/females...
  42. ncbi Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types
    Susan E Schonhoff
    Division of Gastroenterology, GRASP Digestive Disease Center, Tufts New England Medical Center, Boston, MA 02111, USA
    Dev Biol 270:443-54. 2004
    ..Thus, ngn3 expression occurs in mixed populations of immature cells that are not irreversibly committed to endocrine differentiation...
  43. pmc The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear
    Johanna Mantela
    Institute of Biotechnology, University of Helsinki, 00014 Helsinki, Finland
    Development 132:2377-88. 2005
    ..Our findings demonstrate that the pRb pathway is required for hair cell quiescence and that manipulation of the cell cycle machinery disrupts the coordinated development within the inner ear sensory epithelia...
  44. ncbi Essential requirement for both hsf1 and hsf2 transcriptional activity in spermatogenesis and male fertility
    Guanghu Wang
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia
    Genesis 38:66-80. 2004
    ..The findings suggest that additive or synergistic transcriptional activity of both hsf1 and hsf2 is required for normal mammalian spermatogenesis and male fertility...
  45. ncbi Smad2 and Smad3 coordinately regulate craniofacial and endodermal development
    Ye Liu
    Program in Molecular, Cellular, and Developmental Biology, Ohio State University, Columbus, OH 43210 1392, USA
    Dev Biol 270:411-26. 2004
    ..This precedes any defects in anterior patterning and likely causes the abnormalities observed in craniofacial and midline development, as well as hepatogenesis...
  46. ncbi The mammalian twisted gastrulation gene functions in foregut and craniofacial development
    Anna Petryk
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710 3709, USA
    Dev Biol 267:374-86. 2004
    ..In addition, we find defects in the foregut endoderm and a reduction in Hex expression, which may contribute to both the forebrain and BA1 defects...
  47. ncbi Tbx3, the ulnar-mammary syndrome gene, and Tbx2 interact in mammary gland development through a p19Arf/p53-independent pathway
    Loydie A Jerome-Majewska
    Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Dev Dyn 234:922-33. 2005
    ....
  48. ncbi Characterization and molecular methods for detection of a novel spiroplasma pathogenic to Penaeus vannamei
    Linda M Nunan
    Department of Veterinary Sciences and Microbiology, University of Arizona, Tucson, Arizona, 85721, USA
    Dis Aquat Organ 62:255-64. 2004
    ..a digoxigenin-labeled probe was developed and tested. This probe was species-specific, with no positive reactions or cross-reactivity occurring with other bacterial samples tested in this format...
  49. ncbi Efficacy and toxicity of orally administrated anti-coccidial drugs for innovative treatments of Myxobolus sp. infection in Puntazzo puntazzo
    F Athanassopoulou
    Laboratory of Ichthyology and Fish Pathology, University of Thessaly, Faculty of Veterinary Medicine, School of Health Sciences, 221 Trikalon Street, 431 00 Karditsa, Greece
    Dis Aquat Organ 62:217-26. 2004
    ..The SA combination proved the most effective treatment for Myxobolus sp. infection of P. puntazzo as (1) the therapeutic regimen and commercial product was not toxic and (2) a significant reduction occurred in the prevalence rate...
  50. ncbi Heart and skeletal muscle inflammation in Atlantic salmon, Salmo salar L: a new infectious disease
    R T Kongtorp
    National Veterinary Institute, Oslo, Norway
    J Fish Dis 27:351-8. 2004
    ..Further investigations are required in order to make conclusions regarding the cause and pathogenesis of HSMI...
  51. ncbi Experimental infection of turbot, Scophthalmus maximus (L.), by Moritella viscosa, vaccination effort and vaccine-induced side-effects
    B Bjornsdottir
    Institute for Experimental Pathology, University of Iceland, Keldur, Reykjavik, Iceland
    J Fish Dis 27:645-55. 2004
    ..The measurement of various innate humoral immune parameters did not reveal significant differences between vaccinated and control groups...
  52. ncbi Isolation of a rhabdovirus during outbreaks of disease in cyprinid fish species at fishery sites in England
    K Way
    Centre for the Environment, Fisheries and Aquaculture Science Cefas, Barrack Road, Weymouth, Dorset DT4 8UB, UK
    Dis Aquat Organ 57:43-50. 2003
    ..The field observations together with the experimental results indicate that this rhabdovirus is of low virulence but may have the potential to cause significant mortality in fishes under stress...
  53. ncbi Assessment of DNA vaccine potential for gilthead sea bream (Sparus aurata) by intramuscular injection of a reporter gene
    Tiziano Verri
    Department of Biological and Environmental Sciences and Technologies, University of Lecce, Via provinciale Lecce Monteroni, I 73100, Lecce, Italy
    Fish Shellfish Immunol 15:283-95. 2003
    ..i. The results suggest that intramuscular delivery of foreign genes represents a realistic approach for DNA vaccine technology for the prevention of infectious diseases in gilthead sea bream...
  54. ncbi Pathology of heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon Salmo salar
    R T Kongtorp
    National Veterinary Institute, Oslo, Norway
    Dis Aquat Organ 59:217-24. 2004
    ..Microscopic lesions are compared and discussed in relation to published descriptions of pancreas disease (PD) and cardiomyopathy syndrome (CMS). It is concluded that HSMI is histopathologically distinguishable from PD and CMS...
  55. ncbi Studies on transmission and life cycle of Enteromyxum scophthalmi (Myxozoa), an enteric parasite of turbot Scophthalmus maximus
    Maria J Redondo
    Instituto de Acuicultura de Torre de la Sal CSIC, Ribera de Cabanes, 12595 Castellon, Spain
    Folia Parasitol (Praha) 51:188-98. 2004
    ..This may also question the existence of a two-host life cycle involving an actinosporean stage in this species. Further studies are needed to clarify this open point of the life cycle...
  56. ncbi Defeating diplostomoid dangers in USA catfish aquaculture
    Robin M Overstreet
    Department of Coastal Sciences, The University of Southern Mississippi, P O Box 7000, Ocean Springs, Mississippi 9566 7000, USA
    Folia Parasitol (Praha) 51:153-65. 2004
    ..Consequently, management of catfish ponds relative to digenean infections requires considerable biological information on the fish, bird, and snail hosts as well as the parasites...
  57. ncbi Polymicrobic infection of hybrid striped bass (Morone chrysops x Morone saxatilis) with three bacterial pathogens: a case report
    P R Bowser
    Aquatic Animal Health Program, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
    J Fish Dis 27:123-7. 2004
  58. ncbi Pseudomonas anguilliseptica infection in farmed cod, Gadus morhua L
    H W Ferguson
    Veterinary Diagnostic Service, Institute of Aquaculture, University of Stirling, Stirling, UK
    J Fish Dis 27:249-53. 2004
  59. ncbi In vitro efficacy of new antiprotozoals against Philasterides dicentrarchi (Ciliophora, Scuticociliatida)
    A Parama
    Laboratorio de Parasitologia, Instituto de Investigacion y Analisis Alimentarios, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain
    Dis Aquat Organ 62:97-102. 2004
    ..The most promising compound was the pyridothienotriazine 12k, with activity similar to that of the salicylanilides niclosamide and oxiclozanide (MLC 0.8 mg l(-1) in PBS, 1.5 mg l(-1) in seawater; MLC = minimum 24 h lethal concentration)...
  60. ncbi The pathology of chronic erosive dermatopathy in Murray cod, Maccullochella peelii peelii (Mitchell)
    J E Baily
    Institute of Aquaculture, University of Stirling, Stirling, UK
    J Fish Dis 28:3-12. 2005
    ..Canal regeneration occurred when fish were transferred from borehole water into river water. The lack of lesions in other organs and the pattern of lesion development support exposure to waterborne factors as the most likely aetiology...
  61. ncbi Susceptibility of captive adult winter-run Chinook salmon Oncorhynchus tshawytscha to waterborne exposures with infectious hematopoietic necrosis virus (IHNV)
    K D Arkush
    Bodega Marine Laboratory, University of California at Davis, PO Box 247, Bodega Bay, California 94923, USA
    Dis Aquat Organ 59:211-6. 2004
    ....
  62. ncbi Leukocyte and endothelial cell adhesion molecules in a chronic murine model of myocardial reperfusion injury
    S P Jones
    Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
    Am J Physiol Heart Circ Physiol 279:H2196-201. 2000
    ..PMN accumulation in the ischemic-reperfused (I/R) zone was assessed using histological techniques. Deficiencies of P-selectin, E-selectin, ICAM-1, or CD18 resulted in significant (P < 0...
  63. ncbi [Fluorescence serologic and histologic studies of antigen distribution in parvovirus infections in dogs and cats]
    H Weissenbock
    Institut für Pathologie und Gerichtliche Veterinärmedizin der Veterinärmedizinischen Universität Wien
    Zentralbl Veterinarmed B 38:481-91. 1991
    ....
  64. ncbi Tissue diagnosis of Ehrlichia chaffeensis in patients with fatal ehrlichiosis by use of immunohistochemistry, in situ hybridization, and polymerase chain reaction
    J E Dawson
    Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Am J Trop Med Hyg 65:603-9. 2001
    ..Significantly, in 2 of these patients, serologic evidence of infection was absent. Use of IHC, ISH, and PCR to visualize and detect Ehrlichia in tissues can facilitate diagnosis of ehrlichial infections...
  65. ncbi Mesoglia & microglia--a historical review of the concept of mononuclear phagocytes within the central nervous system
    Payam Rezaie
    Department of Neuropathology, Institute of Psychiatry, SE5 8AF, UK
    J Hist Neurosci 11:325-74. 2002
    ..Over the intervening decades, body and substance were added to this concept through the advancement of histological techniques at the disposal of the researcher and the acute and keen-minded skills of the pathologist...
  66. pmc A biological global positioning system: considerations for tracking stem cell behaviors in the whole body
    Shengwen Calvin Li
    Center for Neuroscience and Stem Cell Research, Children s Hospital of Orange County Research Institute, University of California Irvine, 455 South Main Street, Orange, CA 92868, USA
    Stem Cell Rev 6:317-33. 2010
    ..Even though excellent histological techniques remain as the gold standard, no good in vivo techniques are currently available to assess the ..
  67. ncbi Monkey pulpal response to an MMA-based resin cement as adhesive luting for indirect restorations
    Yasushi Shimada
    Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8549, Japan
    J Adhes Dent 7:247-51. 2005
    ..The objective of this study was to evaluate the pulpal response to a newly-developed MMA resin cement (MultiBond, Tokuyama) when used for adhesively luting composite resin inlays...
  68. ncbi Neural control of shark rectal gland
    J S Stoff
    Mount Desert Island Biological Laboratory, Salsbury Cove, Maine 04672
    Am J Physiol 255:R212-6. 1988
    ..Vasoactive intestinal peptide (VIP)-like immunoreactivity was detected by histological techniques in neuronal tissue within the rectal gland...
  69. doi The embryonic development of Schistosoma mansoni eggs: proposal for a new staging system
    Arnon D Jurberg
    Laboratorio de Patologia, Instituto Oswaldo Cruz Fundação Oswaldo Cruz, Pavilhão Gomes de Faria Av Brasil, 4365 Manguinhos, Rio de Janeiro 21040 900, RJ, Brazil
    Dev Genes Evol 219:219-34. 2009
    ..Using classical histological techniques and whole-mount preparations, the present work describes the embryonic development of Schistosoma mansoni ..
  70. ncbi Ultrastructural aspects of the microvasculature of the cochlea: the internal spiral network
    R Penha
    Department of Otorhinolaryngology, Hospital Egas Moniz, Lisbon, Portugal
    Otolaryngol Head Neck Surg 120:725-9. 1999
    ..The comparison of results obtained with each technique gave the perspective of the cochlear microvasculature with great accuracy...
  71. ncbi Identification of immunodominant autoantigens in rat autoimmune orchitis
    Monika Fijak
    Department of Anatomy and Cell Biology, Justus Liebig University of Giessen, D 35385 Giessen, Germany
    J Pathol 207:127-38. 2005
    ..Development of disease was observed using histological techniques and a new non-invasive three-dimensional (3D) imaging technology for in vivo monitoring, termed flat-..
  72. ncbi Warthin tumor: a curious entity--case reports and review of literature
    Alexandra Faur
    Department of Pathology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
    Rom J Morphol Embryol 50:269-73. 2009
    ..the histopathological aspect of Warthin tumors using Hematoxylin-Eosin stain, and immunohistochemical and histological techniques. We reviewed the medical record of patients with salivary gland tumors diagnosed at County Hospital of ..
  73. doi Effect of mangiferin on the development of periodontal disease: involvement of lipoxin A4, anti-chemotaxic action in leukocyte rolling
    Roney Rick Carvalho
    Department of Physiology, Biosciences Institute, Sao Paulo State University UNESP, Rubiao Junior cp 510, 18618 000 Botucatu, Sao Paulo, Brazil
    Chem Biol Interact 179:344-50. 2009
    ..Mangiferin is a polyphenol compound obtained from mango and has been reported to possess antioxidant and anti-inflammatory properties...
  74. ncbi Histological approaches for high-quality imaging of zooplanktonic organisms
    Rossana C N Melo
    Laboratory of Cellular Biology, Department of Biology, Federal University of Juiz de Fora, UFJF, Juiz de Fora, MG, Brazil
    Micron 38:714-21. 2007
    ..can play a structural function as indicators for ecosystem health or stress, but their study using histological techniques is still limited...
  75. ncbi Interstitial laser hyperthermia for colorectal liver metastases: the effect of thermal sensitization and the use of a cylindrical diffuser tip on tumor necrosis
    V Muralidharan
    Department of Surgery, Monash University, Alfred Hospital, Prahran, Australia
    J Clin Laser Med Surg 20:189-96. 2002
    ..The potential synergistic effect between thermal sensitization by metronidazole and interstitial laser hyperthermia (ILH)-induced tumor necrosis is also evaluated...
  76. ncbi Three-dimensional MR microscopy of a transgenic mouse model of dilated cardiomyopathy
    R W Sze
    Department of Radiology, Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Pediatr Radiol 31:55-61. 2001
    ..b>Histological techniques, although providing great anatomic detail, display only "static" data (one time point only) in two ..
  77. ncbi Delayed sclerosis, neuroprotection, and limbic epileptogenesis after status epilepticus in the rat
    Ulrich Ebert
    Department of Pharmacology, Toxicology and Pharmacy, School of Veterinary Medicine, Bunteweg 17, D 30559 Hannover, Germany
    Epilepsia 43:86-95. 2002
    ..e., the development of recurrent spontaneous seizures) during the following weeks...
  78. ncbi Mild carbon monoxide exposure diminishes selectively the integrity of the cochlea of the developing rat
    Ivan Lopez
    Surgery Department, Division of Head and Neck, David Geffen School of Medicine, Los Angeles, California 90095, USA
    J Neurosci Res 74:666-75. 2003
    ..and the neurons of the spiral ganglion were analyzed for their morphology by using immunochemical and histological techniques. The inner and outer hair cells in the organ of Corti of animals exposed to 12 and 25 ppm CO were not ..
  79. ncbi A comparative study on cardiac ganglia in midday gerbil, Egyptian spiny mouse, chinchilla laniger and pigeon
    T Kuder
    Department of Comparative Anatomy, Institute of Biology, Swietokrzyski University, 25 406 Kielce, 15 Swietokrzyska St, Poland
    Anat Histol Embryol 32:134-40. 2003
    Using the thiocholine method and histological techniques, the topography and morphology of cardiac ganglia in midday gerbil, Egyptian spiny mouse, chinchilla laniger and pigeon were studied...
  80. ncbi The AChE-positive ganglia in the trachea and bronchi of the cat
    Tadeusz Kuder
    Department of Comparative Anatomy, Institute of Biology, Swietokrzyski University, Kielce, Poland
    Folia Morphol (Warsz) 62:99-106. 2003
    ..ganglia in the cat were studied using the histochemical-tiocholine method of Koelle and Friedenwald and histological techniques. Intensively stained AChE-positive nerve structures, i.e...
  81. ncbi Structural degeneration of pulmonary homografts used as aortic valve substitute underlines early graft failure
    Dave R Koolbergen
    Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, The Netherlands
    Eur J Cardiothorac Surg 22:802-7. 2002
    ..The mid-term results are evaluated in this study and histological analysis of explanted homografts is performed to investigate the cause of graft failure...
  82. ncbi Impact of heterophil granulocyte depletion caused by 5-fluorouracil on infectious bursal disease virus infection in specific pathogen free chickens
    Susanne Kabell
    Danish Institute for Food and Veterinary Research, Hangøvej 2, DK 8200 Aarhus N, Denmark
    Avian Pathol 35:341-8. 2006
    ..of Fabricius were sampled at fixed intervals, and the progress of the infection was monitored by various histological techniques and reverse transcriptase-polymerase chain reaction (RT-PCR)...
  83. ncbi Evolution of mammalian X-chromosome inactivation: sex chromatin in monotremes and marsupials
    L M McKay
    Department of Genetics and Human Variation, La Trobe University, Bundoora, Vic
    Aust J Biol Sci 40:397-404. 1987
    ..possum, Trichosurus vulpecula) and monotremes (platypus, Ornithorynchus anatinus), using classical histological techniques. A female-specific chromatin body was observed at low frequency in nuclei of possum corneal epithelium, ..
  84. doi Widespread occurrence of the amphibian chytrid fungus Batrachochytrium dendrobatidis in the southeastern USA
    Betsie B Rothermel
    Austin Peay State University, The Center of Excellence for Field Biology, PO Box 4718, Clarksville, Tennessee 37044, USA
    Dis Aquat Organ 82:3-18. 2008
    ..Using histological techniques or PCR assays, we detected chytrid infection in 10 species of aquatic-breeding amphibians in 6 states...
  85. doi Geographical location and age affects the incidence of parasitic infestations in school children
    Paran Rayan
    School of Biomolecular and Biomedical Sciences, Griffith University, Kessels Road, Nathan, Brisbane, Queensland 4111, Australia
    Indian J Pathol Microbiol 53:498-502. 2010
    ..socio-economic zones (rural and urban) were screened for specific intestinal parasites using standard histological techniques. Percentage incidences of parasitic species found in fecal wet mounts and concentrates in rural children ..
  86. ncbi Histological studies of pedicle skin formation and its transformation to antler velvet in red deer (Cervus elaphus)
    C Li
    AgResearch, Invermay Agricultural Centre, Private Bag 50034, Mosgiel, New Zealand
    Anat Rec 260:62-71. 2000
    ..In the present study, we used histological techniques to examine pedicle skin formation and its transformation to antler velvet...
  87. pmc A peptide inhibitor of the urokinase/urokinase receptor system inhibits alteration of the blood-retinal barrier in diabetes
    Deepti Navaratna
    Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA
    FASEB J 22:3310-7. 2008
    ..Biochemical, molecular, and histological techniques were used to examine the role of uPA and uPAR in the regulation of retinal vascular permeability in ..
  88. doi Novel borate glass/chitosan composite as a delivery vehicle for teicoplanin in the treatment of chronic osteomyelitis
    Wei Tao Jia
    Department of Orthopedic Surgery, Shanghai Sixth People s Hospital, Shanghai Jiaotong University, Shanghai 200233, China
    Acta Biomater 6:812-9. 2010
    ..pellets for treating osteomyelitis was evaluated using hematological, radiological, microbiological and histological techniques. When immersed in PBS, the TBGC pellets provided a sustained release of teicoplanin, while the surface of ..
  89. ncbi Computer-assisted complete three-dimensional reconstruction of the mammary ductal/lobular systems: implications of ductal anastomoses for breast-conserving surgery
    T Ohtake
    The Second Department of Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan
    Cancer 91:2263-72. 2001
    ....
  90. doi Interactions between anomalous excretory and tegumental epithelia in aberrant Mesocestoides tetrathyridia from Apodemus sylvaticus in Spain
    David Bruce Conn
    Department of Invertebrate Zoology, Museum of Comparative Zoology, Harvard University, 26 Oxford Street, Cambridge, MA 02138, USA
    Parasitol Res 106:1109-15. 2010
    ..of Apodemus sylvaticus (Rodentia: Muridae) in Murcia, Spain, and processed by routine microscopical and histological techniques, including examination with brightfield, phase-contrast, and differential-interference-contrast optics...
  91. ncbi The effects of soy extract on the uterus of castrated adult rats
    Rejane Mosquette
    Department of Gynecology, Federal University of Sao Paulo, Rua Sena Madureira 1245, 04021051 São Paulo, Brazil
    Maturitas 56:173-83. 2007
    ..The aim of this study was to evaluate the effects of different doses of a standardized soy extract on the uterus of castrated rats...
  92. ncbi Principles of rat subcortical forebrain organization: a study using histological techniques and multiple fluorescence labeling
    A Riedel
    Department of Neuroanatomy, Paul Flechsig Institute for Brain Research, University of Leipzig, Jahnallee 59, D 04109, Leipzig, Germany
    J Chem Neuroanat 23:75-104. 2002
    ....
  93. ncbi The application of amino acid racemization in the acid soluble fraction of enamel to the estimation of the age of human teeth
    R C Griffin
    BioArch, Department of Archaeology, University of York, Heslington YO10 5DD, UK
    Forensic Sci Int 175:11-6. 2008
    ..The majority of existing morphological and histological techniques are highly inaccurate, and show a bias towards underestimating the age of older individuals...
  94. ncbi Imaging vitreous
    J Sebag
    Associate Clinical Professor of Ophthalmology Doheny Eye Institute Keck School of Medicine University of Southern California CA 92648, USA
    Eye (Lond) 16:429-39. 2002
    ..The combined use of more than one technique could provide better imaging of vitreous for future investigational and clinical purposes...
  95. pmc The structure of the cushions in the feet of African elephants (Loxodonta africana)
    G E Weissengruber
    Anatomy, Department of Pathobiology, Veterinary University of Vienna, Austria
    J Anat 209:781-92. 2006
    ..The cushions in the feet of African elephants were examined by means of standard anatomical and histological techniques, computed tomography (CT) and magnetic resonance imaging (MRI)...
  96. pmc Parathyroid hormone receptor type 1/Indian hedgehog expression is preserved in the growth plate of human fetuses affected with fibroblast growth factor receptor type 3 activating mutations
    Sarah Cormier
    Institut National de la Santé et de la Recherche Médicale U426, Assistance Publique Hopitaux de Paris, Hopital Robert Debre, Paris, France
    Am J Pathol 161:1325-35. 2002
    ..21 and 8 thanatophoric dysplasia types 1 and 2, respectively) and 14 age-matched controls by histological techniques and in situ hybridization using riboprobes for human IHH, PTHR1, type 10 and type 1 collagen transcripts...
  97. doi Histochemical visualization and diffusion MRI at 7 Tesla in the TgCRND8 transgenic model of Alzheimer's disease
    Jonathan D Thiessen
    Division of Neurodegenerative Disorders, St Boniface Research Centre, Winnipeg, MB, R2H 2A6, Canada
    Brain Struct Funct 215:29-36. 2010
    ..In our study, we used DWI in the TgCRND8 transgenic model of Alzheimer's disease in conjunction with histological techniques and found robust plaque deposition in the transgenic strain in older animals (12-16 months old)...
  98. doi Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model
    Nongnut Uabundit
    Department of Physiology Neuroscience Program and Graduate School, Faculty of Medicine, Khon Kaen University, Thailand
    J Ethnopharmacol 127:26-31. 2010
    ..Therefore, the potential of this plant to protect against Alzheimer's disease has been raised but less supported document is available...
  99. ncbi Immunohistochemical expression of fibronectin and tenascin after direct pulp capping with calcium hydroxide
    Evandro Piva
    Department of Operative Dentistry, School of Dentistry, Federal University of Pelotas, Pelotas, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:e66-71. 2006
    ..In the exposure site, TNC immunostaining increased over time, exhibiting a thicker immunostaining pattern within 30 days. The imunohistochemical technique showed expression of both glycoproteins during pulp healing process...
  100. doi Karwinskia humboldtiana (buckthorn) fruit causes central nervous system damage during chronic intoxication in the rat
    Eduardo M Becerra-Verdin
    Departamento de Histologia, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, Ave Madero y Eduardo Aguirre Pequeño, A P 1563 Monterrey, Nuevo Leon, Mexico
    Toxicon 53:645-51. 2009
    ..We considered it important to evaluate, with histological techniques, the possible presence of lesions in the brain, by using a model of chronic intoxication that reproduces ..
  101. ncbi [Spermatogenesis--physiology and pathophysiology]
    M Bergmann
    Institut für Veterinär Anatomie, Histologie und Embryologie, Universitat, Giessen
    Urologe A 44:1131-2, 1134-8. 2005
    ..Histological evaluation should be performed using a score count system, and the use of histological techniques for protein and mRNA expression...

Research Grants82

  1. Dystonia in an Animal Model of Kernicterus
    Steven Shapiro; Fiscal Year: 2007
    ..We will use standard histological techniques of injury and cell death including TUNEL and caspase 3 staining for apoptosis, and unbiased stereology to ..
  2. Analysis of MTOPS Tissue Study Data
    Kathleen C Torkko; Fiscal Year: 2010
    ..Lucia and his research group at the University of Colorado Denver used immunohistochemical/histological techniques and advanced computer imaging on biopsy specimens to identify histologic changes associated with BPH ..
  3. In utero availability of the essential nutrient, choline, and mammary cancer risk
    Jan Blusztajn; Fiscal Year: 2007
    ..and supplementation) modulates the development of the mammary gland in female rats as monitored by histological techniques and patterns of gene expression determined by microarrays...
  4. Genetic Dissection of Age-dependent Neuroprotection Mechanisms in Drosophila
    BARRY S GANETZKY; Fiscal Year: 2010
    ..are to determine the in vivo roles of the affected proteins using genetic, molecular, biochemical, and histological techniques to analyze how defects in these proteins result in the observed phenotypes...
  5. SOMATOSENSORY CORTEX AND THALAMUS
    Leah Krubitzer; Fiscal Year: 1999
    ..these experiments, multiple unit, electrophysiological recording methods will be used in combination with histological techniques to identify the number and organization of separate fields in the lateral sulcus in addition to SII and ..
  6. Molecular Improvement of Bacterial Mosquito Larvicides
    Brian Federici; Fiscal Year: 2007
    ..Studies of Cyt1A's mechanism of action will employ a variety of genetic and histological techniques. Bacterial larvicides developed through our studies should improve vector control and disease reduction, ..
  7. Atlas-Based Structural Models of the Mouse Myocardium
    Edward W Hsu; Fiscal Year: 2010
    ..models are methodologically hampered by the labor-intensive and destructive nature of conventional histological techniques. More importantly, since previous models were constructed from limited numbers of specimens, the degree ..
  8. Atlas-Based Structural Models of the Mouse Myocardium
    Edward Hsu; Fiscal Year: 2009
    ..models are methodologically hampered by the labor-intensive and destructive nature of conventional histological techniques. More importantly, since previous models were constructed from limited numbers of specimens, the degree ..
  9. MULTIPARAMETRIC MRI OF CARTILAGE
    Deborah Burstein; Fiscal Year: 2009
    ....
  10. Role of SLc11a1 Gen in Warm Ischemia-Reperfusion Injury
    Samuel Wyllie; Fiscal Year: 2006
    ..Standard biochemical and histological techniques will be employed to evaluate blood transaminases and H&E liver sections, in conjunction with ..
  11. Molecular Improvement of Bacterial Mosquito Larvicides
    Brian Federici; Fiscal Year: 2009
    ..Studies of Cyt1A's mechanism of action will employ a variety of genetic and histological techniques. Bacterial larvicides developed through our studies should improve vector control and disease reduction, ..
  12. The role of Atoh1 in the development and function of Merkel cells
    Stephen M Maricich; Fiscal Year: 2010
    ..We will also use histological techniques to determine the affects of Atoh1 deletion on adult Merkel cells and how this deletion impacts the ..
  13. ANALYSIS OF SPACE BY THE AUDITORY SYSTEM
    ERIC KNUDSEN; Fiscal Year: 1993
    ..A variety of histological techniques will be used to search for anatomical correlates of the plasticity...
  14. Pressure Induced Dynamic 3D Changes in Lamina Cribrosa
    Donald Brown; Fiscal Year: 2007
    ..This technique allows for direct measurement of the structural changes in the associated with glaucoma and has direct clinical relevance and application. ..
  15. EXCITABILITY, SYNAPTIC FUNCTION OF COCHLEAR HAIR CELLS
    Paul Fuchs; Fiscal Year: 2005
    ..b>Histological techniques and quantitative RT-PCR will be used to chart the distribution and development of specific alpha and beta ..
  16. Structural Basis of Ventricular Function
    Xin Yu; Fiscal Year: 2010
    ..The standard histological techniques are destructive and labor intensive...
  17. Evolution of Aging and Dementia in Female Primates
    James Herndon; Fiscal Year: 2007
    ..This comparative analysis also can illuminate the origins of human age-related neurodegenerative disorders such as AD, facilitating the development of treatments for this disease. ..
  18. Structural Basis of Ventricular Function
    Xin Yu; Fiscal Year: 2009
    ..The standard histological techniques are destructive and labor intensive...
  19. Structural Basis of Ventricular Function
    Xin Yu; Fiscal Year: 2007
    ..The standard histological techniques are destructive and labor intensive...
  20. ETB IN REGULATION OF RENAL SODIUM HANDLING
    CHERYL GARIEPY; Fiscal Year: 2003
    ..They will use a variety of biochemical and histological techniques to examine the expression of ETB and its ligands, ET1 and ET3, in the normal kidney during high and low ..
  21. Smart Substrates for a New Generation of Implants
    Irving Shapiro; Fiscal Year: 2009
    ..Following twelve weeks of recovery, femora will be recovered and analyzed using physical, optical, and histological techniques. Outcomes from this study will provide information for engineering of orthopaedic and dental implants ..
  22. Disordered Cellular Cholesterol Movement, Cell Death, and Multisystem Disease
    John M Dietschy; Fiscal Year: 2010
    ..In addition, histological techniques, coupled with measurements of the mRNA expression of proteins reflecting macrophage invasion and ..
  23. THE DEVELOPING AND ADULT VISUAL SYSTEM
    Steven Fisher; Fiscal Year: 1980
    ..The photoreceptor matrix of the California ground squirrel will be determined by histological techniques including the nitro-blue tetrazolium reaction...