cell count

Summary

Summary: The number of CELLS of a specific kind, usually measured per unit volume or area of sample.

Top Publications

  1. ncbi Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease
    M Vasa
    Division of Molecular Cardiology, Department of Internal Medicine IV, University of Frankfurt, Germany
    Circ Res 89:E1-7. 2001
  2. ncbi Circulating endothelial progenitor cells and cardiovascular outcomes
    Nikos Werner
    Division of Cardiology, Angiology, and Intensive Care Medicine, Department of Internal Medicine, University of Saarland, Homburg Saar, Germany
    N Engl J Med 353:999-1007. 2005
  3. pmc Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
    Fabrizio Thorel
    Department of Cell Physiology and Metabolism, University of Geneva Faculty of Medicine, 1 rue Michel Servet, CH 1211 Geneva 4, Switzerland
    Nature 464:1149-54. 2010
  4. ncbi c-Myc regulates mammalian body size by controlling cell number but not cell size
    A Trumpp
    Swiss Institute for Experimental Cancer Research ISREC, Ch des Boveresses 155, CH 1066 Epalinges, Switzerland
    Nature 414:768-73. 2001
  5. doi Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma
    Brian P Buckingham
    Department of Neurological Surgery, University of Washington, Seattle, Washington 98104, USA
    J Neurosci 28:2735-44. 2008
  6. doi Brn3a as a marker of retinal ganglion cells: qualitative and quantitative time course studies in naive and optic nerve-injured retinas
    Francisco M Nadal-Nicolás
    Departamento de Oftalmologia, Facultad de Medicina, Universidad de Murcia, Murcia, Spain
    Invest Ophthalmol Vis Sci 50:3860-8. 2009
  7. ncbi Tumor-associated macrophages: the double-edged sword in cancer progression
    Jeremy J W Chen
    Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan, People s Republic of China
    J Clin Oncol 23:953-64. 2005
  8. ncbi Isotropic fractionator: a simple, rapid method for the quantification of total cell and neuron numbers in the brain
    Suzana Herculano-Houzel
    Departamento de Anatomia, Instituto de Ciencias Biomedicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 21941 590
    J Neurosci 25:2518-21. 2005
  9. ncbi Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
    Anjen Chenn
    Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Science 297:365-9. 2002
  10. pmc De novo neurogenesis in adult hypothalamus as a compensatory mechanism to regulate energy balance
    Andrew A Pierce
    Diabetes Center, University of California, San Francisco, San Francisco, California 94143, USA
    J Neurosci 30:723-30. 2010

Detail Information

Publications298 found, 100 shown here

  1. ncbi Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease
    M Vasa
    Division of Molecular Cardiology, Department of Internal Medicine IV, University of Frankfurt, Germany
    Circ Res 89:E1-7. 2001
    ..The full text of this article is available at http://www.circresaha.org...
  2. ncbi Circulating endothelial progenitor cells and cardiovascular outcomes
    Nikos Werner
    Division of Cardiology, Angiology, and Intensive Care Medicine, Department of Internal Medicine, University of Saarland, Homburg Saar, Germany
    N Engl J Med 353:999-1007. 2005
    ..The number and function of endothelial progenitor cells correlate inversely with cardiovascular risk factors, but the prognostic value associated with circulating endothelial progenitor cells has not been defined...
  3. pmc Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
    Fabrizio Thorel
    Department of Cell Physiology and Metabolism, University of Geneva Faculty of Medicine, 1 rue Michel Servet, CH 1211 Geneva 4, Switzerland
    Nature 464:1149-54. 2010
    ..Such inter-endocrine spontaneous adult cell conversion could be harnessed towards methods of producing beta-cells for diabetes therapies, either in differentiation settings in vitro or in induced regeneration...
  4. ncbi c-Myc regulates mammalian body size by controlling cell number but not cell size
    A Trumpp
    Swiss Institute for Experimental Cancer Research ISREC, Ch des Boveresses 155, CH 1066 Epalinges, Switzerland
    Nature 414:768-73. 2001
    ..We propose that in mammals c-Myc controls the decision to divide or not to divide and thereby functions as a crucial mediator of signals that determine organ and body size...
  5. doi Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma
    Brian P Buckingham
    Department of Neurological Surgery, University of Washington, Seattle, Washington 98104, USA
    J Neurosci 28:2735-44. 2008
    ..This progression of degeneration suggests a need to examine the RGC axon as a locus of pathology in glaucoma...
  6. doi Brn3a as a marker of retinal ganglion cells: qualitative and quantitative time course studies in naive and optic nerve-injured retinas
    Francisco M Nadal-Nicolás
    Departamento de Oftalmologia, Facultad de Medicina, Universidad de Murcia, Murcia, Spain
    Invest Ophthalmol Vis Sci 50:3860-8. 2009
    ..To characterize Brn3a expression in adult albino rat retinal ganglion cells (RGCs) in naïve animals and in animals subjected to complete intraorbital optic nerve transection (IONT) or crush (IONC)...
  7. ncbi Tumor-associated macrophages: the double-edged sword in cancer progression
    Jeremy J W Chen
    Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan, People s Republic of China
    J Clin Oncol 23:953-64. 2005
    ..Inflammation plays a critical role in cancer progression. In this study we investigate the pro-tumorigenic activities and gene expression profiles of lung cancer cells after interaction with macrophages...
  8. ncbi Isotropic fractionator: a simple, rapid method for the quantification of total cell and neuron numbers in the brain
    Suzana Herculano-Houzel
    Departamento de Anatomia, Instituto de Ciencias Biomedicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 21941 590
    J Neurosci 25:2518-21. 2005
    ..Moreover, contrary to what is commonly assumed in the literature, we show that glial cells are not the majority in the rat brain...
  9. ncbi Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
    Anjen Chenn
    Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Science 297:365-9. 2002
    ....
  10. pmc De novo neurogenesis in adult hypothalamus as a compensatory mechanism to regulate energy balance
    Andrew A Pierce
    Diabetes Center, University of California, San Francisco, San Francisco, California 94143, USA
    J Neurosci 30:723-30. 2010
    ..It further suggests that de novo neurogenesis might serve as a compensatory mechanism contributing to the plastic control of energy balance in response to environmental and physiologic insults...
  11. ncbi Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat
    Masafumi Kodama
    Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06508, USA
    Biol Psychiatry 56:570-80. 2004
    ..There has been increasing evidence that atypical antipsychotics are effective in the treatment of mood disorders or for augmenting 5-hydroxytryptamine selective reuptake inhibitors for treatment-resistant depression...
  12. ncbi Immunological aspects in the neurobiology of suicide: elevated microglial density in schizophrenia and depression is associated with suicide
    Johann Steiner
    Department of Psychiatry, University of Magdeburg, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    J Psychiatr Res 42:151-7. 2008
    ..Therefore, the hypothesis of microglial activation during acute psychosis was proposed. Alternatively, "suicide" could be a diagnosis-independent factor leading to microgliosis...
  13. ncbi Descemet-stripping automated endothelial keratoplasty
    Mark S Gorovoy
    Cornea 25:886-9. 2006
    ..To evaluate the speed of visual recovery in 16 consecutive patients with corneal endothelial dysfunction who received Descemet-stripping automated endothelial keratoplasty (DSAEK)...
  14. ncbi Size control in animal development
    I Conlon
    Developmental Neurobiology Programme, Medical Research Council Laboratory for Molecular Cell Biology, University College London, United Kingdom
    Cell 96:235-44. 1999
  15. ncbi Glial reactivity, an early feature of diabetic retinopathy
    E Rungger-Brandle
    Cell Biology Laboratory, University Eye Clinic, Geneva, Switzerland
    Invest Ophthalmol Vis Sci 41:1971-80. 2000
    ..To characterize early structural gliotic reactions in retinal Müller cells, astrocytes, and microglia in experimentally induced diabetes...
  16. ncbi Design-based stereology in neuroscience
    C Schmitz
    Department of Psychiatry and Neuropsychology, Division of Cellular Neuroscience, University of Maastricht, P O Box 616, NL 6200 MD Maastricht, Netherlands
    Neuroscience 130:813-31. 2005
    ..These characteristics establish the advantages of design-based stereologic methods in quantitative neuromorphology...
  17. pmc Decreased number and impaired functionality of endothelial progenitor cells in subjects with metabolic syndrome: implications for increased cardiovascular risk
    I Jialal
    The Laboratory for Atherosclerosis and Metabolic Research, Department of Medical Pathology and Laboratory Medicine, UC Davis Medical Center, Sacramento, CA 95817, USA
    Atherosclerosis 211:297-302. 2010
    ..We aimed to enumerate and functionally characterize EPCs in subjects with MetS in comparison to healthy controls...
  18. ncbi Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach
    C Schmitz
    Department of Anatomy and Cell Biology, RWTH University of Aachen, Pauwelsstrasse Wendlingweg 2, 52057, Aachen, Germany
    J Chem Neuroanat 20:93-114. 2000
    ..In particular, we strongly recommend counting considerably more neurons than is currently done in the literature when estimating total neuronal numbers using design-based stereology...
  19. ncbi Uremia causes endothelial progenitor cell deficiency
    Kirsten de Groot
    Division of Nephrology, Department of Internal Medicine Hannover Medical School, Hannover, Germany
    Kidney Int 66:641-6. 2004
    ..Their number in peripheral blood correlates with endothelial function and cardiovascular risk in humans. We explored whether uremia influences the number of EPCs...
  20. ncbi Notch signalling regulates stem cell numbers in vitro and in vivo
    Andreas Androutsellis-Theotokis
    Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    Nature 442:823-6. 2006
    ..These data indicate that stem cell expansion in vitro and in vivo, two central goals of regenerative medicine, may be achieved by Notch ligands through a pathway that is fundamental to development and cancer...
  21. ncbi Neurogenesis in the adult is involved in the formation of trace memories
    T J Shors
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    Nature 410:372-6. 2001
    ..These results indicate that newly generated neurons in the adult are not only affected by the formation of a hippocampal-dependent memory, but also participate in it...
  22. ncbi Effect of memantine on neuroretinal function and retinal vascular changes of streptozotocin-induced diabetic rats
    Jyotirmoy Kusari
    Department of Biological Sciences, Allergan Inc, Irvine, CA 92623 9534, USA
    Invest Ophthalmol Vis Sci 48:5152-9. 2007
    ..To test whether chronic memantine (MEM) treatment improves retinal function and prevents neurodegeneration and vascular changes in the retinas of streptozotocin (STZ)-induced diabetic rats...
  23. doi Adult hippocampal neurogenesis is involved in anxiety-related behaviors
    J M Revest
    INSERM U862, Neurocenter Magendie, Pathophysiology of Addiction group, Bordeaux, France
    Mol Psychiatry 14:959-67. 2009
    ..Our results indicate that neurogenesis plays an important role in the regulation of affective states and could be the target of new treatments for anxiety disorders...
  24. pmc The Tlx gene regulates the timing of neurogenesis in the cortex
    Kristine Roy
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    J Neurosci 24:8333-45. 2004
    ..These studies indicate that tlx is an essential intrinsic regulator in the decision to proliferate or differentiate in the developing forebrain...
  25. ncbi Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice
    Darren C Robertson
    Department of Preclinical Veterinary Sciences, University of Edinburgh, Summerhall, Edinburgh EH9 1QH, Scotland, UK
    J Neurochem 89:1126-36. 2004
    ....
  26. pmc FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools
    Nick J Van Hateren
    MRC Centre for Developmental and Biomedical Genetics, University of Sheffield, Sheffield, S10 2TN, UK
    Development 138:1893-902. 2011
    ....
  27. ncbi Microglial cell population dynamics in the injured adult central nervous system
    Rune Ladeby
    Medical Biotechnology Center, University of Southern Denmark, Odense C
    Brain Res Brain Res Rev 48:196-206. 2005
    ....
  28. ncbi Vascular damage in a mouse model of diabetic retinopathy: relation to neuronal and glial changes
    Rachel A Feit-Leichman
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 46:4281-7. 2005
    ..The objective of this study was to characterize the occurrence and pathologic progression of diabetic retinopathy in C57Bl/6J mice...
  29. pmc KLF family members regulate intrinsic axon regeneration ability
    Darcie L Moore
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Science 326:298-301. 2009
    ..Thus, coordinated activities of different KLFs regulate the regenerative capacity of CNS neurons...
  30. pmc P2X7 receptor regulates leukocyte infiltrations in rat frontoparietal cortex following status epilepticus
    Ji Eun Kim
    Department of Anatomy and Neurobiology, Institute of Epilepsy Research, College of Medicine, Hallym University, Chunchon 200 702, South Korea
    J Neuroinflammation 7:65. 2010
    ..In the present study, we investigated the roles of P2X7 receptor in recruitment and infiltration of neutrophil during epileptogenesis in rat epilepsy models...
  31. doi High-throughput selection, enumeration, electrokinetic manipulation, and molecular profiling of low-abundance circulating tumor cells using a microfluidic system
    Udara Dharmasiri
    Center for Bio Modular Multi Scale Systems, Louisiana State University, 8000 GSRI Road, Building 3100, Baton Rouge, Louisiana 70820 7403, United States
    Anal Chem 83:2301-9. 2011
    ..However, the HT29 cells did not contain these mutations, consistent with their known genotype...
  32. doi The usefulness of biomarkers of airway inflammation in managing asthma
    Sarita U Patil
    Divsion of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Allergy Asthma Proc 31:259-68. 2010
    ..Combined approaches using simple methods of measuring airway hyperreactivity and obtaining sputum samples hold promise for the future, particularly if rapid analysis of cellular products in sputum can be developed...
  33. doi Distinct structural plasticity in the hippocampus and amygdala of the middle-aged common marmoset (Callithrix jacchus)
    Michael W Marlatt
    Swammerdam Institute for Life Science Center for Neuroscience, University of Amsterdam, Amsterdam, The Netherlands
    Exp Neurol 230:291-301. 2011
    ....
  34. pmc Lack of neuroprotection against experimental glaucoma in c-Jun N-terminal kinase 3 knockout mice
    Harry A Quigley
    Glaucoma Research Laboratory, Wilmer Eye Institute, 600 North Wolfe Street, Johns Hopkins University School of Medicine, Baltimore, MD 21287 9205, USA
    Exp Eye Res 92:299-305. 2011
    ..Counts of RGC layer cells and optic nerve axons indicate that Jnk3(-/-) mice have an increased number of amacrine cells compared to WT controls...
  35. doi Endogenous dopamine regulates the rhythm of expression of the clock protein PER2 in the rat dorsal striatum via daily activation of D2 dopamine receptors
    Suzanne Hood
    Center for Studies in Behavioral Neurobiology Groupe de Recherche en Neurobiologie Comportementale, Department of Psychology, Concordia University, Montreal, Quebec H4B 1R6, Canada
    J Neurosci 30:14046-58. 2010
    ..These observations may have implications for circadian abnormalities seen in Parkinson's disease...
  36. ncbi Initial results of endothelial cell counts after Artisan lens for phakic eyes: an evaluation of the United States Food and Drug Administration Ophtec Study
    Mihai Pop
    Michel Pop Clinics, Montreal, Canada
    Ophthalmology 111:309-17. 2004
    To evaluate the endothelial cell count change in eyes implanted with the iris-claw phakic Artisan lens for treatment of moderate to high myopia.
  37. doi Differential effects of antipsychotic and antidepressant drugs on neurogenic regions in rats
    Henry A Nasrallah
    Dept of Psychiatry, Univ of Cincinnati College of Medicine, Cincinnati, OH 45267 0521, USA
    Brain Res 1354:23-9. 2010
    ..This olfactory model can be employed in human research as a method to explore the neurogenesis effects of various pharmacologic treatments of neuropsychiatric disorders...
  38. pmc The onset of collective behavior in social amoebae
    Thomas Gregor
    Graduate School of Arts and Sciences, University of Tokyo, Tokyo 153 8902, Japan
    Science 328:1021-5. 2010
    ..A quantitative analysis showed that stochastic pulsing of individual cells below the threshold concentration of extracellular cAMP plays a critical role in the onset of collective behavior...
  39. doi Density of CD163+ CD11c+ dendritic cells increases and CD103+ dendritic cells decreases in the coeliac lesion
    A C R Beitnes
    Centre for Immune Regulation, Institute of Immunology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
    Scand J Immunol 74:186-94. 2011
    ....
  40. doi Anti-Müllerian hormone (AMH) defines, independent of age, low versus good live-birth chances in women with severely diminished ovarian reserve
    Norbert Gleicher
    The Center for Human Reproduction and Foundation for Reproductive Medicine, New York, New York 10021, USA
    Fertil Steril 94:2824-7. 2010
    ..04 ng/mL but significantly increased at AMH 0.41-1.05 ng/mL, resulting in similarly low live-birth rates at all AMH levels ≤1.05 ng/mL and significantly improved live-birth rates at AMH ≥1.06 ng/mL...
  41. ncbi Bovine blastocyst development rate in vitro is influenced by selection of oocytes by brillant cresyl blue staining before IVM as indicator for glucose-6-phosphate dehydrogenase activity
    H Alm
    Research Institute for the Biology of Farm Animals, 18196 Dummerstorf, Germany
    Theriogenology 63:2194-205. 2005
    ..In addition, G6PDH activity may be useful as a marker for oocyte quality in future studies on factors affecting developmental competence...
  42. doi Endothelial cell loss after Descemet's stripping endothelial keratoplasty in a large prospective series
    Mark A Terry
    Corneal Services, Devers Eye Institute, Portland, Oregon 97210, USA
    Ophthalmology 115:488-496.e3. 2008
    ..To report the donor endothelial cell loss in the first year after Descemet's stripping endothelial keratoplasty (DSEK) for the treatment of endothelial dysfunction...
  43. ncbi Histomorphometric analysis of the effects of osteocyte density on osteonal morphology and remodeling
    Lionel N Metz
    Orthopaedic Research Laboratory, University of California, Davis Medical Center, Sacramento, CA 95817, USA
    Bone 33:753-9. 2003
    ....
  44. doi Ionizing radiation impairs the formation of trace fear memories and reduces hippocampal neurogenesis
    Pragathi Achanta
    Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249, USA
    Behav Neurosci 123:1036-45. 2009
    ....
  45. ncbi Bone marrow-derived cells that populate the adult mouse brain preserve their hematopoietic identity
    Luc Vallières
    Laboratoire d Endocrinologie Moléculaire, Centre de Recherche du Centre Hospitalier de l Universite Laval, Universite Laval, Quebec, Quebec, G1V 4G2, Canada
    J Neurosci 23:5197-207. 2003
    ..This continuous traffic of macrophages across the blood-brain barrier provides a vehicle to introduce therapeutic genes into the nervous system...
  46. ncbi Mucosal mast cell counts correlate with visceral hypersensitivity in patients with diarrhea predominant irritable bowel syndrome
    Jung Ho Park
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Gastroenterol Hepatol 21:71-8. 2006
    ..Our aim was to determine whether a relationship exists between the number of mucosal mast cells in the gut and visceral hypersensitivity...
  47. ncbi Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization
    Christopher Heeschen
    Department of Internal Medicine IV and Hematology, University of Frankfurt, Germany
    Blood 102:1340-6. 2003
    ..Epo appears to physiologically regulate EPC mobilization in patients with ischemic heart disease. Thus, Epo serum levels may help in identifying patients with impaired EPC recruitment capacity...
  48. ncbi Migration of enhanced green fluorescent protein expressing bone marrow-derived microglia/macrophage into the mouse brain following permanent focal ischemia
    R Tanaka
    Department of Neurology, Juntendo University School of Medicine, 2 1 1, Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Neuroscience 117:531-9. 2003
    ....
  49. ncbi Lost caps in histological counting methods
    J C Hedreen
    Department of Psychiatry, Tufts University School of Medicine, Boston, Massachusetts, USA
    Anat Rec 250:366-72. 1998
    ..e., small object fragments unnoticed or missing at the section surfaces, are an unavoidable issue...
  50. ncbi GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells
    Yusuke Tozuka
    Department of Integrated Biosciences, University of Tokyo, Kashiwa 277 8562, Japan
    Neuron 47:803-15. 2005
    ..Thus, it appears that GABAergic inputs to hippocampal progenitor cells promote activity-dependent neuronal differentiation...
  51. pmc Decreased lung carcinoma cell density on select polymer nanometer surface features for lung replacement therapies
    Lijuan Zhang
    Department of Chemistry, Brown University, Providence, RI 02912, USA
    Int J Nanomedicine 5:269-75. 2010
    ..In this manner, PLGA with specific nanometer surface features may inhibit lung cancer cell density which may provide an important biomaterial for the treatment of lung cancer (from drug delivery to regenerative medicine)...
  52. pmc Postnatal phenotype and localization of spinal cord V1 derived interneurons
    Francisco J Alvarez
    Department of Neuroscience, Cell Biology and Physiology, Wright State University, Dayton, Ohio 45435, USA
    J Comp Neurol 493:177-92. 2005
    ..In summary, V1 interneurons develop into ipsilaterally projecting, inhibitory interneurons that include Renshaw cells, Ia inhibitory interneurons, and other unidentified proprioceptive interneurons...
  53. doi Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats
    Jing Ye Wang
    Department of Neurology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
    Stroke 39:983-90. 2008
    ..In this study, we tested the hypothesis that ischemic postconditioning reduces global cerebral ischemia/reperfusion-induced structural and functional injury in rats...
  54. ncbi Hematopoietic stem cell quiescence maintained by p21cip1/waf1
    T Cheng
    Experimental Hematology, AIDS Research Center, Massachusetts General Hospital Cancer Center, Transplantation Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Science 287:1804-8. 2000
    ..Under conditions of stress, restricted cell cycling is crucial to prevent premature stem cell depletion and hematopoietic death...
  55. ncbi Type 2 diabetes-a matter of beta-cell life and death?
    Christopher J Rhodes
    Pacific Northwest Research Institute, 720 Broadway, Seattle, WA 98122, USA
    Science 307:380-4. 2005
    ..Thus, the IRS-2 pathway appears to be a crucial participant in the tenuous balance between effective pancreatic beta-cell mass and insulin resistance...
  56. ncbi The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas
    N Wierup
    Department of Physiological Sciences, Section of Neuroendocrine Cell Biology, Lund University, BMC F10, 22 184, Lund, Sweden
    Regul Pept 107:63-9. 2002
    ..Specimens from fetal to adult human pancreas and stomach were studied by immunocytochemistry, for ghrelin and islet hormones, and in situ hybridisation, for ghrelin mRNA...
  57. doi Long-term suppression of forebrain neurogenesis and loss of neuronal progenitor cells following prolonged alcohol dependence in rats
    Anita C Hansson
    Laboratory of Clinical and Translational Studies, NIH NIAAA, Bethesda, MD, USA
    Int J Neuropsychopharmacol 13:583-93. 2010
    ..While suppression of hippocampal neurogenesis by alcohol dependence is transient, the suppression in the forebrain SVZ appears long-lasting...
  58. doi Clinical evidence that very small embryonic-like stem cells are mobilized into peripheral blood in patients after stroke
    Edyta Paczkowska
    Department of Physiopathology, Pomeranian Medical University, Szczecin, Poland
    Stroke 40:1237-44. 2009
    ..This raised the question of whether a similar population of cells is mobilized in human stroke patients...
  59. doi One-year follow-up of posterior chamber toric phakic intraocular lens implantation for moderate to high myopic astigmatism
    Kazutaka Kamiya
    Department of Ophthalmology, University of Kitasato School of Medicine, Kanagawa, Japan
    Ophthalmology 117:2287-94. 2010
    ..To assess the 1-year clinical outcomes of toric Visian Implantable Collamer Lens (ICL; STAAR Surgical, Nidau, Switzerland) implantation for moderate to high myopic astigmatism...
  60. doi Quantification of the effect of different levels of IOP in the astroglia of the rat retina ipsilateral and contralateral to experimental glaucoma
    Ana I Ramírez
    Instituto de Investigaciones Oftalmologicas Ramon Castroviejo, Universidad Complutense, Madrid, Spain
    Invest Ophthalmol Vis Sci 51:5690-6. 2010
    ....
  61. doi Automated cell colony counting and analysis using the circular Hough image transform algorithm (CHiTA)
    J M Bewes
    School of Physics, University of Sydney, Sydney, NSW, Australia
    Phys Med Biol 53:5991-6008. 2008
    ..The method was able to identify colonies with unusual morphology, to successfully resolve merged colonies and to correctly count colonies adjacent to flask edges...
  62. pmc Changes in ocular aquaporin expression following optic nerve crush
    Adnan Dibas
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX, USA
    Mol Vis 16:330-40. 2010
    ..This study was designed to analyze changes in the expression of AQP4 (water selective channel) and AQP9 (water and lactate channel) following ONC in the rat...
  63. ncbi Improved survival of young donor age dopamine grafts in a rat model of Parkinson's disease
    E M Torres
    Department of Biosciences, Cardiff University, Museum Avenue, PO Box 911, Cardiff CF10 3US, UK
    Neuroscience 146:1606-17. 2007
    ..We consider the in vivo conditions which allow this differentiation to occur, and the implications for the future of clinical trials based on dopamine cell replacement therapy...
  64. doi Rod-Shaped monocytes patrol the brain vasculature and give rise to perivascular macrophages under the influence of proinflammatory cytokines and angiopoietin-2
    Julie Audoy-Rémus
    Department of Oncology and Molecular Endocrinology, Laval University Hospital Research Center, Quebec City, Quebec, Canada
    J Neurosci 28:10187-99. 2008
    ..This study extends our understanding of the behavior of monocytes at the blood-brain interface and provides a way to block their infiltration into the nervous tissue under inflammatory conditions...
  65. ncbi Neural correlates of cat odor-induced anxiety in rats: region-specific effects of the benzodiazepine midazolam
    Iain S McGregor
    School of Psychology, University of Sydney, Sydney, New South Wales 2006, Australia
    J Neurosci 24:4134-44. 2004
    ..These findings also suggest the intriguing hypothesis that cat odor is processed by rats as a "pheromone-like" stimulus...
  66. doi Chronic high corticosterone reduces neurogenesis in the dentate gyrus of adult male and female rats
    S Brummelte
    Department of Psychology, University of British Columbia, 2136 West Mall, V6T 1Z4 Vancouver, BC, Canada
    Neuroscience 168:680-90. 2010
    ....
  67. ncbi Phosphorylation of Neurogenin2 specifies the migration properties and the dendritic morphology of pyramidal neurons in the neocortex
    Randal Hand
    Department of Phamacology, Neuroscience Center, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Neuron 48:45-62. 2005
    ....
  68. doi Relationship between androgen action in the "male programming window," fetal sertoli cell number, and adult testis size in the rat
    Hayley M Scott
    Medical Research Council Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Queen s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, United Kingdom
    Endocrinology 149:5280-7. 2008
    ..001) with AGD at e21.5, and postnatal d 25 and 90 in animals exposed in utero to vehicle or DBP (e13.5-e21.5). Thus, AGD may predict adult testis size but probably not through a direct relationship with SC number...
  69. doi Notch signaling regulates the extent of hair cell regeneration in the zebrafish lateral line
    Eva Y Ma
    Department of Biological Structure, University of Washington, Seattle, Washington 98195 7420, USA
    J Neurosci 28:2261-73. 2008
    ..Excess hair cells result from increased support cell proliferation. These results suggest a model where Notch signaling limits the number of hair cells produced during regeneration by regulating support cell proliferation...
  70. ncbi Integration of new neurons into functional neural networks
    Victor Ramirez-Amaya
    Arizona Research Laboratories Division of Neural Systems, Memory, and Aging, University of Arizona, Tucson, Arizona 85724, USA
    J Neurosci 26:12237-41. 2006
    ....
  71. ncbi Strain differences affect the induction of status epilepticus and seizure-induced morphological changes
    B Xu
    Department of Psychology, McMaster University, 1280 Main Street West, Hamilton, ON, Canada L8S 4K1
    Eur J Neurosci 20:403-18. 2004
    ..We conclude that genetic factors clearly affect seizure development and related morphological changes in both standard laboratory strains and the selectively bred seizure-prone and seizure-resistant strains...
  72. doi Low natural killer cell cytotoxic activity in autism: the role of glutathione, IL-2 and IL-15
    Aristo Vojdani
    Immunosciences Lab, Inc, 10350 Santa Monica Blvd, Ste 205, Los Angeles, CA 90025, United States
    J Neuroimmunol 205:148-54. 2008
    ..We conclude that that 45% of a subgroup of children with autism suffers from low NK cell activity, and that low intracellular levels of glutathione, IL-2 and IL-15 may be responsible...
  73. doi Visceral fat accumulation induced by a high-fat diet causes the atrophy of mesenteric lymph nodes in obese mice
    C S Kim
    Department of Food Science and Nutrition, University of Ulsan, Ulsan, South Korea
    Obesity (Silver Spring) 16:1261-9. 2008
    ..Because adipose tissue is anatomically associated with lymph nodes, the secondary lymphoid organ, we hypothesized that fat tissue-derived factors may influence the cellularity of lymphoid tissue embedded in fat...
  74. ncbi Differential evolution of PSA-NCAM expression during aging of the rat telencephalon
    Emilio Varea
    Neurobiology Unit and Program in Basic and Applied Neurosciences, Cell Biology Dpt, Universitat de Valencia, Dr Moliner 50, Burjassot 46100, Spain
    Neurobiol Aging 30:808-18. 2009
    ..Given the role of PSA-NCAM in neuronal plasticity, the present results indicate that, even during aging, many regions of the CNS may display neurite, spine or synaptic remodeling...
  75. ncbi Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats
    J Andrew Pospisilik
    Department of Physiology, University of British Columbia, 2146 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada
    Diabetes 52:741-50. 2003
    ..These novel findings provide evidence to support the potential utility of DP IV inhibitors in the treatment of type 1 and possibly late-stage type 2 diabetes...
  76. pmc Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB
    Seok Yong Eum
    International Tuberculosis Research Center, Division of Immunopathology and Cellular Immunology, 475 1, Gapo, Masan 631 320, Republic of Korea
    Chest 137:122-8. 2010
    ..The exact role of neutrophils in the pathogenesis of TB is poorly understood. Recent evidence suggests that neutrophils are not simply scavenging phagocytes in Mycobacterium tuberculosis (Mtb) infection...
  77. ncbi Sexually dimorphic neurogenesis is topographically matched with the anterior accessory olfactory bulb of the adult rat
    P Peretto
    Department of Animal and Human Biology, University of Turin, Via Accademia Albertina 13, 10123 Turin, Italy
    Cell Tissue Res 306:385-9. 2001
    ..Moreover, we demonstrated that the rate of neurogenesis in the anterior AOB of the two sexes was significantly different...
  78. ncbi Mouse embryonic stem cell expansion in a microcarrier-based stirred culture system
    A M Fernandes
    Institute for Biotechnology and Bioengineering IBB, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    J Biotechnol 132:227-36. 2007
    ..Importantly, mES cells expanded under stirred conditions using serum-free medium retained their pluripotency and the ability to commit to the neural lineage...
  79. doi Alterations in lung mast cell populations in patients with chronic obstructive pulmonary disease
    Cecilia K Andersson
    Department of Respiratory Medicine and Allergology, Lund University Hospital, Lund, Sweden
    Am J Respir Crit Care Med 181:206-17. 2010
    ..Mast cells have important roles in innate immunity and tissue remodeling but have remained poorly studied in inflammatory airway diseases like chronic obstructive pulmonary disease (COPD)...
  80. doi Environmental enrichment stimulates progenitor cell proliferation in the amygdala
    Hiroaki Okuda
    Department of Anatomy and Neuroscience, Faculty of Medicine, Nara Medical University, Kashihara City, Nara, Japan
    J Neurosci Res 87:3546-53. 2009
    ..Our findings, taken together with previous behavioral studies, suggest that progenitor proliferation and differentiation in the amygdala may contribute to the beneficial aspects of environmental enrichment such as anxiolytic effects...
  81. ncbi Conserved role of nanos proteins in germ cell development
    Masayuki Tsuda
    Division of Mammalian Development, National Institute of Genetics, SOKENDAI, Yata 1111, Mishima, Shizuoka 411 8540, Japan
    Science 301:1239-41. 2003
    ..Hence, although mice and flies differ in their mechanisms for germ cell specification, there seems to be conserved function for nanos proteins among invertebrates and vertebrates...
  82. ncbi Quantitative analysis of neuronal diversity in the mouse olfactory bulb
    S Parrish-Aungst
    Department of Anatomy and Neurobiology, Program in Neuroscience, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Comp Neurol 501:825-36. 2007
    ..These data suggest that the chemospecific populations of neurons in glomeruli form distinct subpopulations and that GAD isoforms are preferentially regulated in different neurochemical cell types...
  83. pmc Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages
    Lisa C Zaba
    Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York 10021, USA
    J Clin Invest 117:2517-25. 2007
    ..In summary, the normal dermis contains typical immunostimulatory myeloid DCs identified by CD11c and BDCA-1, as well as an additional population of poorly stimulatory macrophages marked by CD163 and FXIIIA...
  84. ncbi Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy
    Teresa Ravizza
    Department of Neuroscience, Laboratory of Experimental Neurology, Mario Negri Institute for Pharmacological Research, Milano, Italy
    Neurobiol Dis 29:142-60. 2008
    ..These data show that specific inflammatory pathways are chronically activated during epileptogenesis and they persist in chronic epileptic tissue, suggesting they may contribute to the etiopathogenesis of TLE...
  85. ncbi An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control
    W Brogiolo
    Zoologisches Institut, Universitat Zurich, Winterthurerstrasse 190, CH 8057, Zurich, Switzerland
    Curr Biol 11:213-21. 2001
    ....
  86. ncbi Neocortical and hippocampal neuron and glial cell numbers in the rhesus monkey
    Jeppe Romme Christensen
    Research Laboratory for Stereology and Neuroscience, Bispebjerg University Hospital, Copenhagen, Denmark
    Anat Rec (Hoboken) 290:330-40. 2007
    ..The results are phylogenetically consistent, apart from the neuron/glia ratio, which is remarkably higher than what is found in other species...
  87. doi Multiple administrations of human marrow stromal cells through cerebrospinal fluid prolong survival in a transgenic mouse model of amyotrophic lateral sclerosis
    Chen Zhang
    Department of Neurology, First Affiliated Hospital of Sun Yat sen University, Guangzhou, Guangdong, corrected PR China
    Cytotherapy 11:299-306. 2009
    ..We investigated the effects of human marrow stromal cells (hMSC) delivered through cerebrospinal fluid (CSF) in a transgenic mouse model of ALS...
  88. ncbi Chymase-positive mast cells play a role in the vascular component of airway remodeling in asthma
    Andrea Zanini
    Salvatore Maugeri Foundation, Division of Pneumology, IRCCS Rehabilitation Institute of Tradate, Tradate, Italy
    J Allergy Clin Immunol 120:329-33. 2007
    ..On the contrary, up to now, no study has addressed the role of chymase-positive mast cells (MC(TC)) in microvasculature changes...
  89. doi Proliferative response of microglia and macrophages in the adult mouse eye after optic nerve lesion
    Stefanie G Wohl
    Hans Berger Department of Neurology, Friedrich Schiller University, Jena, Germany
    Invest Ophthalmol Vis Sci 51:2686-96. 2010
    ..The purpose of this in vivo study was to evaluate the proliferative response of immunologic cells during the acute phase after optic nerve (ON) lesion in the neural retina and the ciliary body (CB) in the adult mouse...
  90. ncbi Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
    Yuval Dor
    Department of Molecular and Cellular Biology and Howard Hughes Medical Institute, Harvard University, 7 Divinity Avenue, Cambridge, Massachusetts 02138, USA
    Nature 429:41-6. 2004
    ..These results suggest that terminally differentiated beta-cells retain a significant proliferative capacity in vivo and cast doubt on the idea that adult stem cells have a significant role in beta-cell replenishment...
  91. pmc Glutamatergic neurons are present in the rat ventral tegmental area
    Tsuyoshi Yamaguchi
    National Institute on Drug Abuse, Cellular Neurophysiology, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Eur J Neurosci 25:106-18. 2007
    ..Based on the results described here, we concluded that the VTA contains glutamatergic neurons that in their vast majority are clearly non-DAergic and non-GABAergic...
  92. doi Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal
    Alexandre Surget
    U930, INSERM, Universite Francois Rabelais de Tours, Tours, France
    Biol Psychiatry 64:293-301. 2008
    ..We investigated causality between changes in hippocampal neurogenesis and the effects of both chronic stress and chronic ADs...
  93. ncbi Astrocytes give rise to new neurons in the adult mammalian hippocampus
    B Seri
    The Rockefeller University, New York, New York 10021, USA
    J Neurosci 21:7153-60. 2001
    ..These results reveal the origins of new neurons in the adult hippocampus...
  94. pmc Low-density neuronal networks cultured using patterned poly-l-lysine on microelectrode arrays
    Sang Beom Jun
    Nano Bioelectronics and Systems Research Center, Seoul, Republic of Korea
    J Neurosci Methods 160:317-26. 2007
    ..Application of DNQX, an AMPA antagonist, blocked all spontaneous activity, suggesting that the activity is excitatory and mediated through glutamate receptors...
  95. ncbi Identification of the neuroprotective molecular region of pigment epithelium-derived factor and its binding sites on motor neurons
    Masako M Bilak
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Neurosci 22:9378-86. 2002
    ..The data support the pharmacotherapeutic potential of PEDF as a neuroprotectant in human motor neuron degeneration...
  96. ncbi Aging of the human cerebellum: a stereological study
    Birgitte Bo Andersen
    Research Laboratory for Stereology and Neuroscience, Bispebjerg University Hospital, 2400 Copenhagen NV, Denmark
    J Comp Neurol 466:356-65. 2003
    ..Furthermore, a 30% loss of volume, mostly due to a cortical volume loss, was recorded in the anterior lobe, which is predominantly involved in motor control...
  97. pmc Effect of ablated hippocampal neurogenesis on the formation and extinction of contextual fear memory
    Hyoung Gon Ko
    National Creative Research Initiative Center for Memory, Department of Biological Sciences, College of Natural Sciences, Seoul National University, San 56 1 Silim dong, Gwanak Gu, Seoul, 151 747, Korea
    Mol Brain 2:1. 2009
    ..These results suggest that although adult newborn neurons contribute to contextual fear memory, they may not be involved in the extinction or erasure of hippocampus-dependent contextual fear memory...
  98. ncbi Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injury
    Hans S Keirstead
    Department of Anatomy and Neurobiology, Reeve Irvine Research Center, College of Medicine, University of California at Irvine, Irvine, California 92697 4292, USA
    J Neurosci 25:4694-705. 2005
    ..These studies document the feasibility of predifferentiating hESCs into functional OPCs and demonstrate their therapeutic potential at early time points after spinal cord injury...
  99. pmc Loss of enteric dopaminergic neurons and associated changes in colon motility in an MPTP mouse model of Parkinson's disease
    Grant Anderson
    Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Exp Neurol 207:4-12. 2007
    ..They provide insight into the impact of dopaminergic dysfunction on gastrointestinal motility and a benchmark for assessment of other PD model systems...
  100. ncbi The role of dopamine receptors in regulating the size of axonal arbors
    C L Parish
    Neurosciences Group, Department of Medicine and Department of Neurology, Monash Medical Center, Clayton 3168, Australia
    J Neurosci 21:5147-57. 2001
    ..These results suggest that individual dopaminergic axons in D2(-/-) mice have reached maximal arbor size. We conclude that the D2 receptor may play a role in modulating the extent of the terminal arbor of SNpc neurons...
  101. ncbi Promoting plasticity in the spinal cord with chondroitinase improves functional recovery after peripheral nerve repair
    Clare M Galtrey
    Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
    Brain 130:926-39. 2007
    ..There was no hyperalgesia. Enhanced plasticity in the spinal cord, therefore, allows the CNS to compensate for inaccurate motor and sensory re-innervation of the periphery, and may be a useful adjunct therapy to peripheral nerve repair...

Research Grants78

  1. HPV & Cervix Neoplasia in a Large, Long Term HIV + Cohort
    Howard D Strickler; Fiscal Year: 2010
    ..Furthermore, beyond total CD4+ T-cell count, the nature of the immune deficits in HIV+ women which effect HPV are poorly understood...
  2. IMPACT OF INTESTINAL DYSFUNCTION ON ANTIRETROVIRAL THERAPY IN INDIA
    RITA CAROLINE ISAAC; Fiscal Year: 2010
    ..Aim 2 will determine the association between intestinal dysfunction and response to HAART as measured by CD4 cell count and BMI at baseline, 6 and 12 months and viral load and viral resistance mutation at baseline and 12 months in a ..
  3. Optimizing Vitamin D Treatment in HIV/AIDS: An RCT
    DOUGLAS THOMAS DIETERICH; Fiscal Year: 2010
    ..The primary outcome measure is the change in the CD4+T cell count. Secondary outcomes include changes in CD4+ T cell subsets, markers of inflammation, markers of bone and calcium ..
  4. In Vivo Flow Cytometry to Measure Circulating Tumor Load
    David Benaron; Fiscal Year: 2004
    ..by the physical flow of cells in the capillaries past a noninvasive optical detector to quantitate target cell count. In Phase I, we construct a fiber-based noninvasive cell detector, optionally including confocal imaging/spatial-..
  5. HIV Therapy & Interruption RCT in Resource Poor Clinic
    Luis Montaner; Fiscal Year: 2007
    ..reconstitution will be evaluated in conjunction with viral suppression to <400 copies/ml and retention of CD4 cell count above baseline at the final observation when both intermittent and continuous study arms are on therapy...
  6. Breast CT scanner for earlier cancer detection
    John Boone; Fiscal Year: 2006
    ..would be detectable far before metastases occurs - for example, a 3 mm tumor contains only 2 percent of the cell count of an 11 mm lesion, and a 5 mm lesion contains only 9 percent of the cell count...
  7. Identification and Significance of Biologic Mediators in Red Cell Concentrates
    Richard P Phipps; Fiscal Year: 2010
    ..Laboratory measures include CD40 ligand, C-reactive protein, D-dimer, blood cell count and differential...
  8. Identification and Significance of Biologic Mediators in Red Cell Concentrates
    Neil Blumberg; Fiscal Year: 2009
    ..Laboratory measures include CD40 ligand, C-reactive protein, D-dimer, blood cell count and differential...
  9. Enhance Prevention in Couples (EPIC)
    Wafaa M El Sadr; Fiscal Year: 2010
    ..interventions: 1) antiretroviral therapy (ART) for the HIV infected partners at threshold of <500 CD4 cell count, 2) couple-focused counseling for decreasing sexual risk behavior and enhancing adherence with ART, and 3) ..
  10. Immunology and Outcomes after HAART in HIV/TB Coinfection
    Gregory P Bisson; Fiscal Year: 2010
    ..These relationships will be examined in adults with advanced HIV infection (as indicated by a pre-HAART CD4 + T cell count <100 cells/mm3) and active TB disease...
  11. Immunology and Outcomes after HAART in HIV/TB Coinfection
    Gregory P Bisson; Fiscal Year: 2010
    ..These relationships will be examined in adults with advanced HIV infection (as indicated by a pre-HAART CD4 + T cell count <100 cells/mm3) and active TB disease...
  12. ENDODONTIC TREATMENT FOR PERSONS WHO ARE HIV POSITIVE
    David Rosenstein; Fiscal Year: 2001
    ..Pretreatment blood samples will be analyzed for CD4 and CD8 cell counts, white blood cell count with differential, p24 antigen level, beta-2 microglobulin level, and erythrocyte sedimentation rate...
  13. Immunology and Outcomes after HAART in HIV/TB Coinfection
    Gregory Bisson; Fiscal Year: 2009
    ..These relationships will be examined in adults with advanced HIV infection (as indicated by a pre-HAART CD4 + T cell count < 100 cells/mm3) and active TB disease...
  14. Monitoring HAART in HIV-infected parents in Thailand
    Marc Lallemant; Fiscal Year: 2007
    ..of the standard antiretroviral monitoring strategy based on VL (VL-S), with a simpler strategy based on CD4+ cell count (CD4-S)...
  15. Novel MRS Methods to Characterize MCMD
    Karl Goodkin; Fiscal Year: 2007
    ..performance; minor cognitive-motor disorder (MCMD)] and pathophysiological indices (plasma HIV-1 RNA load; CD4 cell count; cytotoxic T lymphocyte count)...
  16. HIV/TB in Uganda: Punctuated Antiretroviral Therapy
    Christopher Whalen; Fiscal Year: 2007
    ..We will compare rates of CD4+ cell count decline over 2 years between TB patients who are randomized to either immediate, punctuated ARV therapy given ..
  17. THYMIC FUNCTION IN ADULTS WITH HIV1 DISEASE
    Joseph McCune; Fiscal Year: 2002
    ..of age, radiographic demonstration of thymic tissue was significantly associated with both a higher CD4+ T cell count and a higher percentage and absolute number of circulating naive (CD45RA+CD62L+) CD4+ T cells...
  18. Inflammation and Infection as Risk Factors in Stroke
    Mitchell Elkind; Fiscal Year: 2006
    ..pneumoniae) is associated with stroke risk, and that elevated white blood cell count and soluble tumor necrosis factor receptor levels are associated with carotid atherosclerosis...