body surface area

We sought to validate the improvement by adjustment for body surface area (BSA) of the accuracy of the original Cockcroft-Gault equation to estimate glomerular filtration rate (GFR), in a prospective cross-sectional study of 269 European ..

..In multivariate analysis, two factors had independent predictive value for TEE: a high body surface area (>1.9 m2) (RR: 5 (1.8-13.9)) and an elevated serum lactate dehydrogenase (LDH) (RR: 6.4 (2.3-18.2))...

..A model is presented for estimation of human body surface area (BSA), which is identical in form to the one proposed in 1916 by DuBois and DuBois is presented...

..Normalizing Kt/V to body surface area (S) has been proposed, but the implications of doing this in children have not been examined.

..To review the current dose-calculation practice and propose a non-body-surface area (BSA)-based dose-calculation method...

..30% to 32.7%). CONCLUSION: In view of the high interpatient variability in CL(free) relative to variation in observed BSA, no rationale for continuing BSA-based dosing was found. We recommend fixed-dosing regimens for cisplatin...

b>Body surface area-dosing does not account for the complex processes of cytotoxic drug elimination. This leads to an unpredictable variation in effect...

The majority of cytotoxic drugs for adults are dosed based on body surface area (BSA), aiming to reduce interpatient variability in drug exposure...

..523. Combined kidney volume, corrected for body surface area (corrKV), was independent of age and averaged 240 +/- 45 mL/1.73 m(2)...

b>Body surface area (BSA) was introduced into medical oncology in order to derive a safe starting dose for phase I studies of anticancer drugs from preclinical animal toxicology data...

Values for body surface area (BSA) are commonly used in medicine, particularly to calculate doses of chemotherapeutic agents and index cardiac output. Various BSA formulas have been developed over the years...

..37 x weight; for girls, TBW = 0.14 x (HtWt)0.64 - 0.35 x weight. The height x weight parameter also predicts body surface area (BSA). These equations can be simplified, with slightly less precision, to the following: For boys, TBW = 20...

Estimates of percent body surface area (%BSA) burns correlate well with fluid needs, nutritional requirements, and prognosis. Most burn centers rely on the Lund Browder chart and "rule of nines," to calculate the %BSA...

..This study is designed to determine a formula predicting total liver volume (TLV) based on body surface area (BSA) or body weight in Western adults. TLV was measured in 292 patients from four Western centers...

BACKGROUND: The importance of deciding the appropriate dose of anticancer agents cannot be overemphasized. Body surface area (BSA) has been used to calculate the dose in anticancer therapy since the 1950s...

..Therefore, the body surface area of ST elevation and the presence of late potentials were compared to the inducibility of VT in patients with ..

The prescribed dose of anticancer agents is most commonly calculated using body surface area as the only independent variable, and it has been shown that this approach still results in large interpatient variability in drug exposure...

..We aimed to establish normal values for LAEDD using CMR and a fast gradient-echo sequence with steady-state free precession (SSFP)...

..and lower extremities were affected equally by Buruli ulcers, if correction was made for differences in body surface area. Patients from outside the Amansie West district presented significantly more often with ulcerated lesions, ..

..The area of the palmar surface of one hand has been estimated to be 1 percent of the body surface area. The area of the palmar surface of the hand was measured to test the accuracy of this estimate and then ..

Accurate determination of body surface area (BSA) in experimental animals is essential for modeling effects of burn injury or drug metabolism...

..Our goal was to determine the prevalence and characteristics of aortic valve disease in girls and women with monosomy for the X chromosome, or Turner syndrome (TS)...

..The thoracic aortic diameters of the patients were measured at nine positions. Adjustment for body surface area (BSA) was performed...

..Fill volume should be scaled for body surface area (mL/m2) and, to avoid a hyperpermeable exchange, for a not-too-small amount...

The purpose of our study was to evaluate the effect of body weight, height, body surface area (BSA), body mass index (BMI), and obesity on aortic contrast enhancement in cardiac MDCT.

..of several demographic and anthropometric parameters [age, body weight, height, body mass index, and body surface area (BSA)] on serum peak TSH levels after rhTSH administration...

..intervals measured by Doppler tissue imaging (DTI) and to determine the effects of age, heart rate (HR), and body surface area on DTI-derived time intervals in children. We studied 593 children with normal echocardiogram results...

..normal echocardiograms from 634 children aged 1 day to 18 years, heart rate (HR) range of 50 to 194/min, and body surface area (BSA) range of 0.1 to 2.8 m2...

..In an attempt to reduce this variability, most chemotherapy doses are individualised according to patient body surface area (BSA)...

..the effects of the methods of Doppler tissue imaging (DTI) versus pulse wave Doppler (PWD) and age, body surface area (BSA), and heart rate on the RVTX in a population of 308 children with normal echocardiogram findings...

..These findings provide a rationale for the conduct of a comparative phase III study between BSA-based dosing and flat or fixed dosing of CPT-11...

..An exploratory study to test whether body-surface area (BSA) should be used for the calculation of epirubicin dose...

The majority of chemotherapy regimens and trials specify doses of cytotoxic drugs normalized to body surface area. Estimation of BSA in paediatric patients is particularly problematic, as conventional nomograms require accurate ..

The aim of this study was to investigate the relationship between body surface area (BS) and bone mineral density (BMD) and the associated osteoporosis risk at various skeletal regions in women from mainland China...

..To determine normal limits for ascending and descending thoracic aorta diameters in a large population of asymptomatic, low-risk adult subjects...

..patients were transported to the respective hospitals within 3 days after suffering burns and their total body surface area of burns was greater than 20%. Fourteen of the 34 patients (41...

..guidelines for graded minimum resection weight recommendations, which have relied on the body weight or the body surface area, parameters that both had a much lower correlation to the resected breast tissue in the patient group than ..

..There were 39 deaths related to scalds. Large burn size was the strongest predictor of mortality followed by the presence of inhalation injury and the length of time to intravenous access...

..Data of liver weight (LW), body weight (BW), body height (BH), body surface area (BSA), and age were obtained from 652 postmortem examination reports (age, 42.4 +/- 16...

..It is difficult to predict the blood loss that will occur per operation and how many units the patient will require during surgery. This may result in high cross-match-to-transfusion ratios (CMTRs)...

..Patients ranged in age from 3 to 18 years, with flame or scald burns covering more than 40% of their body surface area. At 1...

Age, aetiology of burn, percentage body surface area burnt and post-burn sequelae have a direct relationship to the rehabilitative necessity in burnt children in a developing country--India...

..7 patients each year; heterotopic ossification was seen in 4 patients (0.4%); 4 patients (0.4%) developed stage II-IV pressure sores; hypothermia was present in 0.8% of patients...

..Ninety-five percent of the severely burned children from this institute had significant hepatomegaly identified at autopsy...

..These findings support the need for safer product design and more specific warnings in product labeling and instructions as to the danger of severe scald injury to minimize the occurrence of such injuries...

..RESULTS: Thirty-five children (M: 20; F: 15; Age range: 6 months to 10 years) were identified. The total body surface area of the burn was between <1 and 5%. Hand or fingers were the commonest sites involved...

..First and second years of life were the peak of incidence. The mean extent of burn was 14.0% total body surface area with 950 patients (7.7%) suffering from a burn extent >/=40% TBSA. Scalds resulted in 5085 admissions (43...

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..Gender was not a factor for high mortality in any age group. The mortality rate showed mildly decreasing tendency since 1995 for which implementation of skin bank was thought to be responsible...

..Their median age was 17.5 months and median body surface area burned was 4% (range, 0.25% to 32%)...

..b>Body surface area (m2; SA) was also assessed...

..The purpose of this study was to analyze the influence of age and gender on resting energy expenditure (REE) in severely burned children from acute hospitalization through 12 months postburn...

..purpose of this study was to determine the normal standards of liver, spleen, and kidney dimensions and the relationship of each with sex, age, body weight, height, body mass index, and body surface area in healthy school-aged children.

..Domestic burns accounted for 84.7% of admissions. Median burn area was 4% of the total body surface area with a range of 0.2-45%...

..The mean age was 17.10 years (1-60 years) and 61.50% of the patients were female. The mean total body surface area (TBSA) burned was 21.09% (6-58) and 88% of the patients had third-degree burns...

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..Scalds accounted for 13 cases, one contact burn occurred from a hot grill. The median total body surface area burned was 5.7% (range 1.5-26%). The National Census of 2002 recorded a population of 3,917,203...

..The model has been evaluated and can be used in the design of rational dosing strategies for L-AmB antifungal therapy in this special population...

..The authors conclude that the inconsistency in AUC can be reduced 10-fold with dosing proportional to the weight and the drug pharmacokinetic parameters [(weight0.7)/(Cmaxxt1/2(0.5))]...

..METHODS: Twenty-five pediatric patients with greater than 40% total body surface area burns were studied...

..from 354 cadaveric donors with respect to gender, age, body weight, body height, body mass index (BMI), and body surface area (BSA). In men, pancreas weight correlated more closely with body weight than with age, height, or BMI...

..Since venous diameters are largely unknown at different ages, the purpose of this study was to correlate innominate vein (INN) and superior vena cava (SVC) diameters with body dimensions in growing children...

..Gender and nationality had no influence on incidence or mortality. These findings will hopefully stimulate development of targeted and sustainable interventions for reducing burns occurrence among identified paediatric high-risk groups...

..between the genders, and relations of the diameters of the coronary arteries to age, height, weight, body surface area, and the diameter of the descending aorta were examined...

..Left ventricular mass has been adjusted to height, to height2.7(h2.7) and to body surface area (BSA)...

..old) with mixed partial- and full-thickness burns involving the trunk, extremities, or both, averaging 7% of body surface area (range: 1% to 24%), were reviewed. Patients received acoustic pressure wound therapy with standard burn care...

..7%) were the commonest type under 10 years of age. The present study will contribute to taking and disseminating safety measures by determining general properties and risk factors of such preventable deaths...

..4+/-14.6% versus 6.6+/-13.26%, TBSA). Pediatric burns in younger children should be studied closely as to their causes and with further follow-up...

..drugs used for human immunodeficiency virus (HIV)-infected children with dose recommendations based on body surface area calculations...

..Much of this is behaviour related, and it is hoped that through preventative measures a marked reduction in the number of Asian ethnic minority burns can be achieved...

..Changes in referral patterns over this period resulted in a decrease in the mean total body surface area of injury, an increase in the number of admissions and an increase in the time interval from injury to ..

..This retrospective study evaluated the epidemiology of burn injuries, due to paint thinner ignition, in patients treated at the burn units of a university hospital network...

..The total body surface area of adults and children were similar, i.e. 7.15 +/- 5.49% versus 7.23 +/- 6.87%...

..To asses the values of echocardiographic measurements in normal children without cardiopathy and to build percentile curves, relating them to the body surface (BS, m(2))...

..To investigate with ultrasonography (US) normal spleen length in healthy children...

..2% occurred in workplace and domestic accidents were more frequent among women. The mean total body surface area (TBSA) burned was 7.4+/-14.3%...

..The study describes the pharmacokinetics (PK) of the protease inhibitor nelfinavir and its active metabolite M8 in children and evaluates the influence of patient-related factors on nelfinavir plasma levels...

..Percutaneous decompression is a safe and effective method of decreasing IAH and preventing ACS in patients with less than 80% TBSA thermal injury...

..able to compare individuals of differing size, glomerular filtration rate (GFR) is conventionally indexed to body surface area (BSA)...

..This study sought to investigate the development of left ventricular remodeling during active cycling...

..Liver weight (LW) was plotted against age, height, body weight (BW), body surface area (BSA) or body mass index (BMI); a formula was developed using simple regression: LW (g) = 772 (g/m(2)) x BSA,..

..of children were estimated using the equation constructed based upon the autopsy data in literature, and body surface area (BSA) was calculated using a standard formula...

..4% were > or =60 years old. Ninety-six percent had burns covering less than half of body surface area and 31.7% had only full thickness skin burn...

..Wound colonization and sepsis were diminished in the early treatment group as well. CONCLUSION: Early excision and concurrent aggressive feeding attenuate muscle catabolism and improve infectious outcomes after burn...

..IVCD was expressed per body surface area. RESULTS: Following haemodialysis mean IVCD (average of expiration and inspiration) decreased from 1.12+/-0...

..It is necessary to specify the regression model, 95% Cl or correlation coefficient of LA(50) in probit analysis or linear regression, respectively, when LA(50) of one sample is compared with that of another...

..In addition, the clinical effect of cardiac growth and other demographic and echocardiographic parameters on DTI velocities during childhood has not been adequately evaluated...

..The aim of the present study was to compare SUV measurements based on body weight, body surface area and lean body mass in the pediatric population and to determine a more reliable parameter across all ages...

..58:1. The median age was 2.5 years and the median burn size was 5% total body surface area (TBSA). Toddlers of age < 2 years accounted for 235 (42.7%) of admission...

..The smaller cross-sectional area confers a biomechanical disadvantage that, coupled with the greater body weight, increases the vulnerability to fracture after a fall...

..This relation must be handled cautiously when comparing the severity score of two groups of patients, just as any other severity score that uses a linear relation with the burnt area associated or not to age...

..Normal values for all these parameters vary as a function of age, body weight and body surface area. They are briefly described here.

..Perforation, evolution of a mediastinitis or peritonitis with multi-organ failure are devastating complications with extremely high mortality and warrants immediate surgical treatment...

..The rate of chronic kidney disease (CKD) secondary to diabetes and/or hypertension is on the rise, and the related health care costs represent a significant economic burden...

..The following variables were studied: age, sex, body weight, body surface area, preoperative body temperature, ASA physical status, history of diabetic neuropathy, emergency surgery, ..

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..As dapsone is administered topically, it was expected that systemic absorption would be considerably lower than that observed with oral dapsone therapy, thereby avoiding any adverse haematological effects...

..To investigate the effect of carbachol (CAR) on blood flow of intestinal mucosa and absorption rate of glucose-electrolyte solution (GES) during enteral resuscitation of burn shock in dog...

..of this number between 6,400 and 11,200 have severe burns covering at least 20% of the person's total body surface area (BSA). Twenty years ago burns covering half of a person's BSA were fatal...

..of this number between 6,400 and 11,200 have severe burns covering at least 20% of the person's total body surface area (BSA). Twenty years ago burns covering half of a person's BSA were fatal...

..of this number between 6,400 and 11,200 have severe burns covering at least 20% of the person's total body surface area (BSA). Twenty years ago burns covering half of a person's BSA were fatal...

..A Severity Weighted Assessment Tool (SWAT), a determination of the percentage involvement of total body surface area, and, if present, assessment of clinically abnormal lymph nodes (>1 cm diameter) will be completed at ..

..This emergent, high-morbidity disease causes destructive skin ulcers that may cover up to 15% of the body surface area. Secondary infection of the ulcers is extremely rare...

..A 40 percent body surface area burn to the flank of approximately 5 percent local burn to the lower leg and examination of the ..

..of scaling methods to include anthropometric parameters (total body mass, body height, lean body mass, body surface area, and body mass index), tissue volumes (active marrow and spongiosa), and tissue masses (active marrow and ..

..However; after adjusting for all co-morbidities including body surface area, female gender is an independent predictor of increased mortality following CABG, with a risk adjusted ..

..However;after adjusting for all co-morbidities including body surface area, female gender is an independent predictor of increased mortality following CABG, with a risk adjusted ..

..which originally hypothesized that hypermetabolic responses to a thermal injury greater than 40% total body surface area burned, persisted throughout the first year post burn, and was partially mediated by an increase in the ..

..projects stable dose as a function of variability contributed by clinical factors including gender, age, body surface area, diabetes status, heart valves, concomitant use of CYP2C9 inducers, and genetic factors including CYP2C9 and ..

..of PM"s inappropriate portentiated responses will be carried out in a rat model of 30 percent total body surface area burn plus an intraabdominal inoculation of Enterococcus faecalis using two strains of the organism, one ..

..of PM"s inappropriate portentiated responses will be carried out in a rat model of 30 percent total body surface area burn plus an intraabdominal inoculation of Enterococcus faecalis using two strains of the organism, one ..

..projects stable dose as a function of variability contributed by clinical factors including gender, age, body surface area, diabetes status, heart valves, concomitant use of CYP2C9 inducers, and genetic factors including CYP2C9 and ..

..be variable with some patients having only elbows and knees involved while others have 50% or more of their body surface area involved. Therapy depends on the severity of the disease...

..We have utilized a murine scald burn model (3rd degree, 25% total body surface area) and our preliminary results indicated that at 4-7 days post-burn Mphi were "hyperactive" (increased ..

..We have utilized a murine scald burn model (3rd degree, 25 percent total body surface area) and our preliminary results indicated that at 4-7 days post-burn Mphi were "hyperactive" as increased ..

..dosing has traditionally been empiric, with all patients receiving the same dose adjusted for body surface area (BSA)...

..Aim 4: To evaluate the clinical and prognostic utility of measured glomerular filtration rate normalized to body surface area compared to serum creatinine, estimated or measured creatinine clearance, estimated glomerular filtration ..

..in immune dysfunction that results from the combined insult of acute ethanol exposure and a 15% total body surface area dorsal scald injury...