artifacts

Summary

Summary: Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.

Top Publications

  1. ncbi Overcoming artifacts from metallic orthopedic implants at high-field-strength MR imaging and multi-detector CT
    Mi Jung Lee
    Department of Diagnostic Radiology and Research Institute of Radiological Science and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 134 Sincheon Dong Seodaemun Gu, Seoul 120 752, Republic of Korea
    Radiographics 27:791-803. 2007
  2. pmc Reducing the effects of PCR amplification and sequencing artifacts on 16S rRNA-based studies
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 6:e27310. 2011
  3. ncbi Removing electroencephalographic artifacts by blind source separation
    T P Jung
    Howard Hughes Medical Institute, Salk Institute, San Diego, California, USA
    Psychophysiology 37:163-78. 2000
  4. ncbi Image distortion correction in fMRI: A quantitative evaluation
    Chloe Hutton
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London WCIN 3BG, United Kingdom
    Neuroimage 16:217-40. 2002
  5. ncbi Image-based method for retrospective correction of physiological motion effects in fMRI: RETROICOR
    G H Glover
    Department of Radiology, Stanford University School of Medicine, Center for Advanced MR Technology at Stanford, Stanford, California, USA
    Magn Reson Med 44:162-7. 2000
  6. ncbi Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI
    Rasmus M Birn
    Laboratory of Brain and Cognition, National Institute of Mental Health, NIH, 10 Center Dr, Bldg 10, Rm 1D80 Bethesda, MD 20892 1148, USA
    Neuroimage 31:1536-48. 2006
  7. pmc PCR-induced sequence artifacts and bias: insights from comparison of two 16S rRNA clone libraries constructed from the same sample
    Silvia G Acinas
    Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Appl Environ Microbiol 71:8966-9. 2005
  8. ncbi Removal of eye activity artifacts from visual event-related potentials in normal and clinical subjects
    T P Jung
    University of California, San Diego, La Jolla, CA 92093, USA
    Clin Neurophysiol 111:1745-58. 2000
  9. ncbi RESTORE: robust estimation of tensors by outlier rejection
    Lin Ching Chang
    Section on Tissue Biophysics and Biomimetics, Laboratory of Integrative Medicine and Biophysics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Magn Reson Med 53:1088-95. 2005
  10. pmc Heteroduplexes in mixed-template amplifications: formation, consequence and elimination by 'reconditioning PCR'
    Janelle R Thompson
    Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, Cambridge, MA 02139, USA
    Nucleic Acids Res 30:2083-8. 2002

Detail Information

Publications347 found, 100 shown here

  1. ncbi Overcoming artifacts from metallic orthopedic implants at high-field-strength MR imaging and multi-detector CT
    Mi Jung Lee
    Department of Diagnostic Radiology and Research Institute of Radiological Science and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 134 Sincheon Dong Seodaemun Gu, Seoul 120 752, Republic of Korea
    Radiographics 27:791-803. 2007
    At magnetic resonance (MR) imaging and multidetector computed tomography (CT), artifacts arising from metallic orthopedic hardware are an obstacle to obtaining optimal images...
  2. pmc Reducing the effects of PCR amplification and sequencing artifacts on 16S rRNA-based studies
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 6:e27310. 2011
    ....
  3. ncbi Removing electroencephalographic artifacts by blind source separation
    T P Jung
    Howard Hughes Medical Institute, Salk Institute, San Diego, California, USA
    Psychophysiology 37:163-78. 2000
    ..Many methods have been proposed to remove artifacts from EEG recordings, especially those arising from eye movements and blinks...
  4. ncbi Image distortion correction in fMRI: A quantitative evaluation
    Chloe Hutton
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London WCIN 3BG, United Kingdom
    Neuroimage 16:217-40. 2002
    ..but requires postprocessing to improve the robustness of the acquired field map and reduce any secondary artifacts. Furthermore, the distribution of the internal magnetic field throughout the head is position dependent ..
  5. ncbi Image-based method for retrospective correction of physiological motion effects in fMRI: RETROICOR
    G H Glover
    Department of Radiology, Stanford University School of Medicine, Center for Advanced MR Technology at Stanford, Stanford, California, USA
    Magn Reson Med 44:162-7. 2000
    ..The method is found to perform well for both respiration- and cardiac-induced noise without imposing spatial filtering on the correction. Magn Reson Med 44:162-167, 2000...
  6. ncbi Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI
    Rasmus M Birn
    Laboratory of Brain and Cognition, National Institute of Mental Health, NIH, 10 Center Dr, Bldg 10, Rm 1D80 Bethesda, MD 20892 1148, USA
    Neuroimage 31:1536-48. 2006
    ..Regressing out global signal changes or cueing the subject to breathe at a constant rate and depth resulted in an improved spatial overlap between deactivations and resting-state correlations among areas that showed deactivation...
  7. pmc PCR-induced sequence artifacts and bias: insights from comparison of two 16S rRNA clone libraries constructed from the same sample
    Silvia G Acinas
    Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Appl Environ Microbiol 71:8966-9. 2005
    The contribution of PCR artifacts to 16S rRNA gene sequence diversity from a complex bacterioplankton sample was estimated...
  8. ncbi Removal of eye activity artifacts from visual event-related potentials in normal and clinical subjects
    T P Jung
    University of California, San Diego, La Jolla, CA 92093, USA
    Clin Neurophysiol 111:1745-58. 2000
    ..Often, all epochs contaminated by large eye artifacts are rejected as unusable, though this may prove unacceptable when blinks and eye movements occur frequently.
  9. ncbi RESTORE: robust estimation of tensors by outlier rejection
    Lin Ching Chang
    Section on Tissue Biophysics and Biomimetics, Laboratory of Integrative Medicine and Biophysics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Magn Reson Med 53:1088-95. 2005
    ..in diffusion weighted imaging (DWI) is influenced by both thermal noise and spatially and temporally varying artifacts such as subject motion and cardiac pulsation...
  10. pmc Heteroduplexes in mixed-template amplifications: formation, consequence and elimination by 'reconditioning PCR'
    Janelle R Thompson
    Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, Cambridge, MA 02139, USA
    Nucleic Acids Res 30:2083-8. 2002
    Although it has been recognized that PCR amplification of mixed templates may generate sequence artifacts, the mechanisms of their formation, frequency and potential elimination have not been fully elucidated...
  11. doi Evaluation of artifacts and distortions of titanium applicators on 3.0-Tesla MRI: feasibility of titanium applicators in MRI-guided brachytherapy for gynecological cancer
    Yusung Kim
    Department of Radiation Oncology, University of Iowa, Iowa City, IA 52242, USA
    Int J Radiat Oncol Biol Phys 80:947-55. 2011
    The aim of this study was to characterize the levels of artifacts and distortions of titanium applicators on 3.0-Tesla magnetic resonance imaging (MRI).
  12. ncbi A fully automated correction method of EOG artifacts in EEG recordings
    A Schlogl
    Institute of Human Computer Interfaces, Graz University of Technology, Krenngasse 37 IV, A 8010 Graz, Austria
    Clin Neurophysiol 118:98-104. 2007
    A fully automated method for reducing EOG artifacts is presented and validated.
  13. pmc Removal of movement artifact from high-density EEG recorded during walking and running
    Joseph T Gwin
    Human Neuromechanics Laboratory, School of Kinesiology University of Michigan, Ann Arbor, Michigan, USA
    J Neurophysiol 103:3526-34. 2010
    ..These findings show that high-density EEG can be used to study brain dynamics during whole body movements and that mechanical artifact from rhythmic gait events may be minimized using a template regression procedure...
  14. ncbi Detection of sonographic B-lines in patients with normal lung or radiographic alveolar consolidation
    Giovanni Volpicelli
    Department of Emergency Medicine, San Luigi Gonzaga Hospital, Torino, Italy
    Med Sci Monit 14:CR122-8. 2008
    Diffuse comet-tail B-line artifacts in lung ultrasound are a sign of alveolar-interstitial syndrome, but isolated transthoracic scans positive for B-lines (multiple B lines or B+) could be detected in other conditions...
  15. ncbi Addressing a systematic vibration artifact in diffusion-weighted MRI
    Daniel Gallichan
    Centre for Functional Magnetic Resonance Imaging of the Brain, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
    Hum Brain Mapp 31:193-202. 2010
    ..We also demonstrate that the artifact may be avoided by acquiring full k-space data, and that subsequent increases in TE can be avoided by employing parallel acceleration...
  16. pmc DNA sequences from multiple amplifications reveal artifacts induced by cytosine deamination in ancient DNA
    M Hofreiter
    Max Planck Institute for Evolutionary Anthropology, Inselstrasse 22, D-04103 Leipzig, Germany
    Nucleic Acids Res 29:4793-9. 2001
    ..1% even under the unlikely scenario where each amplification starts from a single template molecule...
  17. doi Correcting eddy current and motion effects by affine whole-brain registrations: evaluation of three-dimensional distortions and comparison with slicewise correction
    Siawoosh Mohammadi
    Department of Neurology, University of Munster, Albert Schweitzer Straße 33, D 48129 Munster, Germany
    Magn Reson Med 64:1047-56. 2010
    ....
  18. pmc Activity inference for Ambient Intelligence through handling artifacts in a healthcare environment
    Francisco E Martínez-Pérez
    Facultad de Ingenieria, Universidad Autonoma de Baja California, Km 103 Carretera Tijuana Ensenada, Ensenada, B C 022860, Mexico
    Sensors (Basel) 12:1072-99. 2012
    ..We discuss how the use of RBs might positively impact the problems faced by designers and developers for recovering information in an easier manner and thus they can develop tools focused on the user...
  19. ncbi Immunolabeling artifacts and the need for live-cell imaging
    Ulrike Schnell
    Department of Cell Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Nat Methods 9:152-8. 2012
    ....
  20. pmc fMRI in the presence of task-correlated breathing variations
    Rasmus M Birn
    Laboratory of Brain and Cognition, National Institute of Mental Health, NIH, 10 Center Dr, Bldg 10, Rm 1D80, Bethesda, MD 20892 1148, USA
    Neuroimage 47:1092-104. 2009
    ....
  21. pmc Electromyogenic artifacts and electroencephalographic inferences
    Alexander J Shackman
    Laboratory for Affective Neuroscience and Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin, W J Brogden Hall, 1202 West Johnson Street, Madison, WI 53706, USA
    Brain Topogr 22:7-12. 2009
    ..We conclude by describing emerging methodological trends in this area that are likely to have substantial benefits for basic and applied EEG research...
  22. doi Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations--many questions, some answers
    Robert Landsiedel
    Department of Product Safety, BASF SE, 67056 Ludwigshafen, Germany
    Mutat Res 681:241-58. 2009
    ..This review should help to improve standard genotoxicity testing as well as investigations on the underlying mechanism and the interpretation of genotoxicity data on nanomaterials...
  23. ncbi Artifacts in CT: recognition and avoidance
    Julia F Barrett
    Imaging Performance Assessment of CT Scanners, St George s Hospital, Blackshaw Rd, London SW17 0QT, England
    Radiographics 24:1679-91. 2004
    b>Artifacts can seriously degrade the quality of computed tomographic (CT) images, sometimes to the point of making them diagnostically unusable...
  24. ncbi 3.0 T vs. 1.5 T MR angiography: in vitro comparison of intravascular stent artifacts
    Alexander Wall
    Department of Clinical Radiology, University of Munster, Munster, Germany
    J Magn Reson Imaging 22:772-9. 2005
    ..To evaluate the signal characteristics of different iliac artery stents in MR angiography (MRA) at 3 T in comparison with 1.5 T...
  25. ncbi Measuring rDNA diversity in eukaryotic microbial systems: how intragenomic variation, pseudogenes, and PCR artifacts confound biodiversity estimates
    Daniel J Thornhill
    Department of Biological Sciences, Auburn University, 101 Rouse Life Sciences Building, Auburn, Alabama 36849, USA
    Mol Ecol 16:5326-40. 2007
    ..These considerations must be taken into account when interpreting sequence data generated by bacterial cloning of multicopy genes such as rDNA...
  26. pmc Algorithm-driven artifacts in median Polish summarization of microarray data
    Federico M Giorgi
    Max Planck Institute of Molecular Plant Physiology, Am Muehlenberg 1, 14476 Golm, Germany
    BMC Bioinformatics 11:553. 2010
    ....
  27. ncbi Spiral-in/out BOLD fMRI for increased SNR and reduced susceptibility artifacts
    G H Glover
    Department of Radiology, Center for Advanced MR Technology, Stanford University School of Medicine, Stanford, California 94305 5488, USA
    Magn Reson Med 46:515-22. 2001
    ..be combined in several ways to simultaneously achieve increased signal-to-noise ratio (SNR) and reduced dropout artifacts. Activation experiments employing an olfaction task demonstrate significantly increased activation volumes due ..
  28. doi Reducing chimera formation during PCR amplification to ensure accurate genotyping
    R P Smyth
    Centre for Virology, Burnet Institute, 85 Commercial Road, Melbourne, Victoria, Australia
    Gene 469:45-51. 2010
    ..This procedure will facilitate the generation of data sets that more accurately reflect the underlying population diversity rather than artifacts introduced by the process itself.
  29. doi Reducing abdominal CT radiation dose with adaptive statistical iterative reconstruction technique
    Priyanka Prakash
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Invest Radiol 45:202-10. 2010
    ..To assess radiation dose reduction for abdominal computed tomography (CT) examinations with adaptive statistical iterative reconstruction (ASIR) technique...
  30. ncbi Issues of spectral quality in clinical 1H-magnetic resonance spectroscopy and a gallery of artifacts
    Roland Kreis
    Department of Clinical Research, Unit for MR Spectroscopy and Methodology, University Berne, Switzerland
    NMR Biomed 17:361-81. 2004
    ..Furthermore, artifacts are not at all conspicuous in MRS and can easily be taken for true, interpretable features...
  31. pmc Identification and resolution of artifacts in the interpretation of imprinted gene expression
    Charlotte Proudhon
    Institut Curie in Paris, France
    Brief Funct Genomics 9:374-84. 2010
    ..A very large number of technical and biological artifacts can also lead to the erroneous evidence of imprinted gene expression...
  32. doi Evaluation of two iterative techniques for reducing metal artifacts in computed tomography
    F Edward Boas
    Department of Radiology, Stanford University Medical Center, 300 Pasteur Dr, Room H 1307, Stanford, CA 94305, USA
    Radiology 259:894-902. 2011
    To evaluate two methods for reducing metal artifacts in computed tomography (CT)--the metal deletion technique (MDT) and the selective algebraic reconstruction technique (SART)--and compare these methods with filtered back projection (..
  33. ncbi Automatic correction of ocular artifacts in the EEG: a comparison of regression-based and component-based methods
    Garrick L Wallstrom
    Center for Biomedical Informatics, University of Pittsburgh, Forbes Tower Suite 8084, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Int J Psychophysiol 53:105-19. 2004
    A variety of procedures have been proposed to correct ocular artifacts in the electroencephalogram (EEG), including methods based on regression, principal components analysis (PCA) and independent component analysis (ICA)...
  34. ncbi Patching cardiac and head motion artefacts in diffusion-weighted images
    Marcel P Zwiers
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, HB Nijmegen, The Netherlands
    Neuroimage 53:565-75. 2010
    ..The method is not limited to diffusion tensor imaging but also yields objective artefact reflecting weights that can be used to inform subsequent processing or estimation of higher-order diffusion models...
  35. doi Multidistance probe arrangement to eliminate artifacts in functional near-infrared spectroscopy
    Toru Yamada
    National Institute of Advanced Industrial Science and Technology, Neuroscience Research Institute, 1 1 1 Umezono Central 2, Tsukuba, Ibaraki 305 8568, Japan
    J Biomed Opt 14:064034. 2009
    ..practical fNIRS measurements, a subject's physical or systemic physiological activities often cause undesirable artifacts. Such activities can be evoked even by task execution...
  36. doi Comparison of dual-source CT coronary angiography and conventional coronary angiography for detecting coronary artery disease
    Yi Xu
    Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China
    Int J Cardiovasc Imaging 26:75-81. 2010
    ..076). The diagnostic performance of DSCT-CCTA is generally as accurate as that of CAG. Thus, DSCT-CCTA is a reliable non-invasive method for detecting coronary artery stenosis...
  37. doi Automatic removal of eye-movement and blink artifacts from EEG signals
    Jun Feng Gao
    Research Institute of Biomedical Engineering, Xi an Jiaotong University, China
    Brain Topogr 23:105-14. 2010
    Frequent occurrence of electrooculography (EOG) artifacts leads to serious problems in interpreting and analyzing the electroencephalogram (EEG)...
  38. pmc Image reconstruction in circular cone-beam computed tomography by constrained, total-variation minimization
    Emil Y Sidky
    Department of Radiology MC 2026, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Phys Med Biol 53:4777-807. 2008
    ..It appears to be robust against cone-beam artifacts, and may be particularly useful when the angular range is limited or when the angular sampling rate is low...
  39. pmc Single-cell copy number variation detection
    Jiqiu Cheng
    Department of Electrical Engineering, ESAT SCD, Katholieke Universiteit Leuven, Kasteelpark Arenberg 10, Leuven 3001, Belgium
    Genome Biol 12:R80. 2011
    ..However, such detection is challenging because of the genome artifacts and the DNA amplification process inherent to the single cell approach...
  40. pmc Arrhythmia ECG noise reduction by ensemble empirical mode decomposition
    Kang Ming Chang
    Department of Photonics and Communication Engineering, Asia University, Wufeng, Taichung County, 500, Lioufeng Rd, Wufeng, Taichung County, 41354, Taiwan
    Sensors (Basel) 10:6063-80. 2010
    A novel noise filtering algorithm based on ensemble empirical mode decomposition (EEMD) is proposed to remove artifacts in electrocardiogram (ECG) traces...
  41. ncbi Analysis and visualization of single-trial event-related potentials
    T P Jung
    Institute for Neural Computation, University of California San Diego, La Jolla, California 92093 0523, USA
    Hum Brain Mapp 14:166-85. 2001
    ..plus 22 neurological patients whose EEG records were heavily contaminated with blink and other eye-movement artifacts. Results show that ICA can separate artifactual, stimulus-locked, response-locked, and non-event-related ..
  42. pmc Confidence-based somatic mutation evaluation and prioritization
    Martin Löwer
    TRON Translational Oncology at Johannes Gutenberg University of Mainz Medicine, Mainz, Germany
    PLoS Comput Biol 8:e1002714. 2012
    ..Using the HiSeq 2000, single end 50 nt reads from replicates generate the highest confidence somatic mutation call set...
  43. doi Retrospective gating vs. prospective triggering for noninvasive coronary angiography: Assessment of image quality and radiation dose using a 256-slice CT scanner with 270 ms gantry rotation
    Wei Yip Law
    Department of Radiology, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan, ROC
    Acad Radiol 18:31-9. 2011
    ....
  44. doi The role of physiological noise in resting-state functional connectivity
    Rasmus M Birn
    Department of Psychiatry, University of Wisconsin Madison, Madison, WI 53719, USA
    Neuroimage 62:864-70. 2012
    ....
  45. doi ICA-based muscle artefact correction of EEG data: what is muscle and what is brain? Comment on McMenamin et al
    Sebastian Olbrich
    Department of Psychiatry and Psychotherapy of the University Clinic of Leipzig, Leipzig, Germany
    Neuroimage 54:1-3; discussion 4-9. 2011
    ..ICA-based artefact correction already provides a powerful tool for muscle artefact rejection. More research is needed for determining reliable criteria to delineate myogenic from neurogenic components...
  46. doi Suppression of metal artifacts in CT using a reconstruction procedure that combines MAP and projection completion
    Catherine Lemmens
    Department of Nuclear Medicine, K U Leuven, B 3000 Leuven, Belgium
    IEEE Trans Med Imaging 28:250-60. 2009
    Metal implants such as hip prostheses and dental fillings produce streak and star artifacts in the reconstructed computed tomography (CT) images. Due to these artifacts, the CT image may not be diagnostically usable...
  47. pmc ChIP on Chip: surprising results are often artifacts
    Torsten Waldminghaus
    Department of Cell Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital and University of Oslo, 0310 Oslo, Norway
    BMC Genomics 11:414. 2010
    ..The method of chromatin immunoprecipitation combined with microarrays (ChIP-Chip) is a powerful tool for genome-wide analysis of protein binding. However, a high background signal is a common phenomenon...
  48. pmc Identification and correction of abnormal, incomplete and mispredicted proteins in public databases
    Alinda Nagy
    Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, H 1113 Budapest, Hungary
    BMC Bioinformatics 9:353. 2008
    ....
  49. doi Comparison of principal and independent component analysis in removing extracerebral interference from near-infrared spectroscopy signals
    Jaakko Virtanen
    Helsinki University of Technology, Department of Biomedical Engineering and Computational Science, P O Box 3310, FI 02015 TKK, Helsinki, Finland
    J Biomed Opt 14:054032. 2009
    ..Performance differences between PCA and ICA could be attributed primarily to different criteria for identifying the surface effect...
  50. pmc Physiological noise and signal-to-noise ratio in fMRI with multi-channel array coils
    Christina Triantafyllou
    Athinoula A Martinos Imaging Center at McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Neuroimage 55:597-606. 2011
    ..At higher acceleration factors, image SNR is reduced and the time-series becomes increasingly thermal noise dominant. However, the tSNR reduction is smaller than the reduction in image SNR due to the presence of physiological noise...
  51. doi Validation of ICA as a tool to remove eye movement artifacts from EEG/ERP
    Maarten Mennes
    Department of Woman and Child, KU Leuven, Leuven, Belgium
    Psychophysiology 47:1142-50. 2010
    Eye movement artifacts in electroencephalogram (EEG) recordings can greatly distort grand mean event-related potential (ERP) waveforms. Different techniques have been suggested to remove these artifacts prior to ERP analysis...
  52. ncbi In vitro evaluation of intravascular stent artifacts in three-dimensional MR angiography
    D Maintz
    Department of Diagnostic Radiology, University of Cologne, School of Medicine, Cologne, Germany
    Invest Radiol 36:218-24. 2001
    ..To evaluate the intraluminal signal characteristics of various stents and stent-grafts in contrast-enhanced three-dimensional MR angiography (3D MRA) in vitro...
  53. ncbi The correction of ocular artifacts: a topographic perspective
    T W Picton
    Rotman Research Institute, University of Toronto, Ontario, Canada
    Clin Neurophysiol 111:53-65. 2000
    ..To evaluate the scalp topography of the potentials related to saccades and blinks...
  54. doi Semi-automatic identification of independent components representing EEG artifact
    Filipa Campos Viola
    MRC Institute of Hearing Research, Southampton, UK
    Clin Neurophysiol 120:868-77. 2009
    ..component analysis (ICA) can disentangle multi-channel electroencephalogram (EEG) signals into a number of artifacts and brain-related signals...
  55. ncbi Improved quality of auditory event-related potentials recorded simultaneously with 3-T fMRI: removal of the ballistocardiogram artefact
    Stefan Debener
    MRC Institute of Hearing Research Southampton, Royal South Hants Hospital, School of Medicine, University of Southampton, UK
    Neuroimage 34:587-97. 2007
    ....
  56. ncbi Abdomen: diffusion-weighted MR imaging with pulse-triggered single-shot sequences
    Petra Mürtz
    Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
    Radiology 224:258-64. 2002
    ..Pulse triggering to the diastolic heart phase led to reduced motion artifacts on the diffusion-weighted MR images and to significantly improved accuracy and reproducibility of measurements ..
  57. doi Diffusion imaging in humans at 7T using readout-segmented EPI and GRAPPA
    Robin M Heidemann
    Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
    Magn Reson Med 64:9-14. 2010
    ..Readout-segmented echo-planar imaging in conjunction with parallel imaging has the potential to reduce these artifacts by allowing a further reduction in effective echo spacing during the echo-planar imaging readout...
  58. pmc Validation of ICA-based myogenic artifact correction for scalp and source-localized EEG
    Brenton W McMenamin
    Department of Psychology, Center for Cognitive Science, University of Minnesota, Twin Cities, Minneapolis, MN, USA
    Neuroimage 49:2416-32. 2010
    ..In light of these results, several practical suggestions and recommendations are made for intelligently using ICA to minimize EMG and other common artifacts.
  59. ncbi Hand-held thoracic sonography for detecting post-traumatic pneumothoraces: the Extended Focused Assessment with Sonography for Trauma (EFAST)
    A W Kirkpatrick
    Department of Critical Care Medicine, Foothills Medical Centre, Calgary, Alberta, Canada
    J Trauma 57:288-95. 2004
    ..However, the diagnostic utility of hand-held US has not been previously evaluated in this role...
  60. doi Metastatic colorectal cancer KRAS genotyping in routine practice: results and pitfalls
    Aude Lamy
    Laboratory of Tumor Genetics, University Hospital, Rouen, France
    Mod Pathol 24:1090-100. 2011
    ..The tumor heterogeneity observed in some patients indicates that it should be more appropriate to perform KRAS genotyping on metastases if sample is available...
  61. ncbi Multidetector-row computed tomography imaging characteristics of mechanical prosthetic valves
    Petr Symersky
    Department of Cardiothoracic Surgery, Isala Klinieken Zwolle, The Netherlands
    J Heart Valve Dis 20:216-22. 2011
    ..A pulsatile in vitro model was developed to study the MDCT imaging characteristics of mechanical heart valves (MHVs)...
  62. pmc Influence of heart rate on the BOLD signal: the cardiac response function
    Catie Chang
    Department of Electrical Engineering, Stanford University, Lucas MRI S Center, Stanford, CA 94305 5488, USA
    Neuroimage 44:857-69. 2009
    ..s previously-described respiration response function. Furthermore, it is shown that modeling out RV and HR can significantly alter functional connectivity maps of the default-mode network...
  63. ncbi Neurophysiological predictor of SMR-based BCI performance
    Benjamin Blankertz
    Machine Learning Laboratory, Berlin Institute of Technology, Germany
    Neuroimage 51:1303-9. 2010
    ....
  64. ncbi AAPM/RSNA physics tutorial for residents: MR artifacts, safety, and quality control
    Jiachen Zhuo
    Department of Radiology, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201, USA
    Radiographics 26:275-97. 2006
    b>Artifacts in magnetic resonance (MR) imaging result from the complex interaction of contemporary imager subsystems, including the main magnet, gradient coils, radiofrequency (RF) transmitter and receiver, and reconstruction algorithm ..
  65. ncbi Local noise weighted filtering for emphysema scoring of low-dose CT images
    Arnold M R Schilham
    Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 25:451-63. 2006
    ..NOVA filtering of a CT image of typically 400 x 512 x 512 voxels takes only a couple of minutes which makes it suitable for routine use in clinical practice...
  66. ncbi Comparison of detrending methods for optimal fMRI preprocessing
    Jody Tanabe
    Department of Radiology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Neuroimage 15:902-7. 2002
    ..However, auto-detrending (selecting the best algorithm or none, if detrending is not useful) appears to be the most judicious choice, particularly for analyzing fMRI data with weak activations in the presence of baseline drift...
  67. ncbi EMG and EOG artifacts in brain computer interface systems: A survey
    Mehrdad Fatourechi
    Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada V6T 1Z4
    Clin Neurophysiol 118:480-94. 2007
    ..b>Artifacts are undesirable signals that can interfere with neurological phenomena...
  68. doi High-resolution maps of magnetization transfer with inherent correction for RF inhomogeneity and T1 relaxation obtained from 3D FLASH MRI
    Gunther Helms
    MR Forschung in der Neurologie und Psychiatrie, Universitatsmedizin Gottingen, Gottingen, Germany
    Magn Reson Med 60:1396-407. 2008
    ..It is inherently compensated for inhomogeneities of receive and transmit RF fields. The MT saturation appeared to be a sensitive parameter to depict MS lesions and alterations of normal-appearing white matter...
  69. ncbi BOLD contrast sensitivity enhancement and artifact reduction with multiecho EPI: parallel-acquired inhomogeneity-desensitized fMRI
    Benedikt A Poser
    FC Donders Centre for Cognitive Neuroimaging, Nijmegen, The Netherlands
    Magn Reson Med 55:1227-35. 2006
    ..A method is presented that uses accelerated parallel imaging to reduce image artifacts and acquire images at multiple TEs following a single excitation, with no need to increase TR...
  70. pmc Impact of whole genome amplification on analysis of copy number variants
    T J Pugh
    Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada
    Nucleic Acids Res 36:e80. 2008
    ..We demonstrated that the WGA procedure introduces hundreds of potentially confounding CNV artifacts that can obscure detection of bona fide variants...
  71. ncbi Minimizing clip artifacts in multi CT angiography of clipped patients
    I van der Schaaf
    Department of Radiology, University Medical Center Utrecht, Best, The Netherlands
    AJNR Am J Neuroradiol 27:60-6. 2006
    ..of pitch, kilovoltage peak (kVp), reconstruction algorithm, type, and orientation of the clip on clip-induced artifacts was investigated in a phantom study...
  72. ncbi Removal of FMRI environment artifacts from EEG data using optimal basis sets
    R K Niazy
    University of Oxford, Centre for Functional MRI of the Brain FMRIB, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Neuroimage 28:720-37. 2005
    ..However, EEG data collected in such experiments suffer from two kinds of artifact. First, gradient artifacts are caused by the switching of magnetic gradients during FMRI...
  73. pmc Detecting and adjusting for artifacts in fMRI time series data
    Jorn Diedrichsen
    Department of Biomedical Engineering, Laboratory for Computational Motor Control, Johns Hopkins University School of Medicine, Baltimore, 720 Rutland Ave, 416 Traylor Building, MD 21205 2195, USA
    Neuroimage 27:624-34. 2005
    We present a new method to detect and adjust for noise and artifacts in functional MRI time series data...
  74. ncbi MR imaging of vascular stents: effects of susceptibility, flow, and radiofrequency eddy currents
    L W Bartels
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan, The Netherlands
    J Vasc Interv Radiol 12:365-71. 2001
    The purpose of this in vitro study was to examine the various sources of artifacts in magnetic resonance (MR) imaging and angiography of vascular stents.
  75. ncbi Colored noise and computational inference in neurophysiological (fMRI) time series analysis: resampling methods in time and wavelet domains
    E Bullmore
    Department of Psychiatry, University of Cambridge, United Kingdom
    Hum Brain Mapp 12:61-78. 2001
    ..We conclude that wavelet resampling may be a generally useful method for inference on naturally complex time series...
  76. ncbi Evaluation of image artifact produced by optical coherence tomography of retinal pathology
    Robin Ray
    Department of Ophthalmology, Duke University Eye Center, Durham, North Carolina 27710, USA
    Am J Ophthalmol 139:18-29. 2005
    To determine the frequency and type of optical coherence tomography (OCT) fast macular thickness map (FMTM) scan artifacts, and whether these artifacts depend on patient diagnosis, demographics, and ocular therapy.
  77. ncbi High resolution single-shot EPI at 7T
    Oliver Speck
    Department of Biomedical Magnetic Resonance, Faculty of Natural Sciences Institute for Experimental Physics, Otto von Guericke University Magdeburg, Leipziger Str 44, Haus 01, 39120 Magdeburg, Germany
    MAGMA 21:73-86. 2008
    ..This study developed and tested pulse sequence and protocol modifications required to allow high resolution EPI for whole brain functional neuroimaging...
  78. ncbi Ultrasound diagnosis of occult pneumothorax
    Daniel A Lichtenstein
    Medical Intensive Care Unit, Hopital Ambroise Pare, Boulogne Paris Ouest, France
    Crit Care Med 33:1231-8. 2005
    ..Pneumothorax can be missed by bedside radiography, and computed tomography is the current alternative. We asked whether lung ultrasound could be of any help in this situation...
  79. pmc Phase-sensitive inversion recovery for detecting myocardial infarction using gadolinium-delayed hyperenhancement
    Peter Kellman
    Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 47:372-83. 2002
    ..Phase-sensitive detection also has the advantage of decreasing the sensitivity to changes in tissue T(1) with increasing delay from contrast agent injection...
  80. pmc Molecular dynamics simulations of lipid bilayers: major artifacts due to truncating electrostatic interactions
    M Patra
    Biophysics and Statistical Mechanics Group, Laboratory of Computational Engineering, Helsinki University of Technology, FIN 02015 HUT, Finland
    Biophys J 84:3636-45. 2003
    ..The results obtained using PME, on the other hand, are consistent with experiments. These artifacts are interpreted in terms of radial distribution functions g(r) of molecules and molecular groups in the bilayer ..
  81. pmc Correcting motion artifacts in retinal spectral domain optical coherence tomography via image registration
    Susanna Ricco
    Department of Computer Science, Duke University, Durham, NC, USA
    Med Image Comput Comput Assist Interv 12:100-7. 2009
    ..We propose a method to correct for transverse motion artifacts in SD-OCT volumes after scan acquisition by registering the volume to an instantaneous, and therefore artifact-..
  82. ncbi Low-dose quantitative myocardial blood flow imaging using 15O-water and PET without attenuation correction
    Mark Lubberink
    Department of Nuclear Medicine and PET Research, VU University Medical Centre, Amsterdam, The Netherlands
    J Nucl Med 51:575-80. 2010
    Misalignment between PET and low-dose CT (LD-CT) can cause severe artifacts in cardiac PET/CT because of attenuation-correction errors, even when using slow or cine LD-CT...
  83. pmc Limited copy number-high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies
    Hongdo Do
    Department of Pathology, University of Melbourne, Parkville, Victoria, 3010, Australia
    Mol Cancer 8:82. 2009
    ..The dilutions used (based on Ct values) are chosen such that mutations, if present, can be detected by the direct sequencing of amplicons with aberrant melting patterns...
  84. doi US artifacts
    Myra K Feldman
    Department of Radiology, Western Pennsylvania Hospital, 4800 Friendship Ave, Pittsburgh, PA 15224, USA
    Radiographics 29:1179-89. 2009
    Image artifacts are commonly encountered in clinical ultrasonography (US) and may be a source of confusion for the interpreting physician. Some artifacts may be avoidable and arise secondary to improper scanning technique...
  85. pmc Metal-related artifacts in instrumented spine. Techniques for reducing artifacts in CT and MRI: state of the art
    P Stradiotti
    IRCCS Istituto Ortopedico Galeazzi, Via R Galeazzi 4, Milan 20161, Italy
    Eur Spine J 18:102-8. 2009
    ..MRI and CT imaging can be more helpful, using cross-sectional view. However, the presence of metal-related artifacts at both conventional CT and MRI imaging can obscure relevant anatomy and disease...
  86. ncbi How to perform an accurate assessment of cardiac function in mice using high-resolution magnetic resonance imaging
    Jurgen E Schneider
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, UK
    J Cardiovasc Magn Reson 8:693-701. 2006
    ..Here, we describe a protocol that allows for a quick and reproducible approach of obtaining the relevant cardiac views for cine-MRI, and we explain how an accurate experimental image analysis can be performed...
  87. pmc Visual inspection of independent components: defining a procedure for artifact removal from fMRI data
    Robert E Kelly
    Weill Cornell Institute of Geriatric Psychiatry, Weill Cornell Medical College, 21 Bloomingdale Road, White Plains, NY 10605, USA
    J Neurosci Methods 189:233-45. 2010
    b>Artifacts in functional magnetic resonance imaging (fMRI) data, primarily those related to motion and physiological sources, negatively impact the functional signal-to-noise ratio in fMRI studies, even after conventional fMRI ..
  88. pmc A component based noise correction method (CompCor) for BOLD and perfusion based fMRI
    Yashar Behzadi
    UCSD Center for Functional Magnetic Resonance Imaging and Department of Radiology, 9500 Gilman Drive, MC 0677, La Jolla, CA 92093 0677, USA
    Neuroimage 37:90-101. 2007
    ..In comparison to RETROICOR, CompCor has the advantage of not requiring external monitoring of physiological fluctuations...
  89. ncbi Development and validation of segmentation and interpolation techniques in sinograms for metal artifact suppression in CT
    Wouter J H Veldkamp
    Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Med Phys 37:620-8. 2010
    Metal prostheses cause artifacts in computed tomography (CT) images...
  90. doi Antisense transcripts of V(D)J rearrangements; artifacts caused by false priming?
    Yuan Zhao
    Department of Immunobiology, King s College London, Guy s Hospital Campus, St Thomas St, London SE1 9RT, UK
    Mol Immunol 46:2357-62. 2009
    ....
  91. pmc Physiological recordings: basic concepts and implementation during functional magnetic resonance imaging
    Marcus A Gray
    Clinical Imaging Sciences Centre and Department of Psychiatry, Brighton and Sussex Medical School, University of Sussex, Falmer Campus, UK
    Neuroimage 47:1105-15. 2009
    ..We review the sources of these potential problems and the current approaches and advice to enable the combination of fMRI and physiological monitoring in a safe and effective manner...
  92. doi Rejection of pulse related artefact (PRA) from continuous electroencephalographic (EEG) time series recorded during functional magnetic resonance imaging (fMRI) using constraint independent component analysis (cICA)
    Yves Leclercq
    Cyclotron Research Centre, University of Liege, Belgium
    Neuroimage 44:679-91. 2009
    ..Using multichannel EEG recordings obtained in a 3 T MR scanner, with and without concomitant fMRI acquisition, we provide evidence for the sensitivity and specificity of the method in rejecting PRA in various sleep and waking conditions...
  93. ncbi Optimisation of the 3D MDEFT sequence for anatomical brain imaging: technical implications at 1.5 and 3 T
    R Deichmann
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London WC1N 3BG, UK
    Neuroimage 21:757-67. 2004
    ..It is shown both theoretically and experimentally that these problems can be avoided by using spin tagging and fat saturation...
  94. ncbi Synchronization of neuronal activity in the human primary motor cortex by transcranial magnetic stimulation: an EEG study
    T Paus
    Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada
    J Neurophysiol 86:1983-90. 2001
    ..As such, they corroborate previous studies of cortical oscillations in the motor cortex and point to the potential of the combined TMS/EEG approach for further investigations of cortical rhythms in the human brain...
  95. doi Evaluation of coronary artery in-stent restenosis with prospectively ECG-triggered axial CT angiography versus retrospective technique: a phantom study
    W J Yang
    Department of Radiology, Rui Jin Hospital, Medical School, Shanghai Jiao Tong University, No 197, Rui Jin Er Road, Shanghai, 200025, China
    Radiol Med 116:189-96. 2011
    ..This study compared the performance of prospectively electrocardiographically (ECG)-triggered axial computed tomography (CT) angiography with retrospective technique in evaluating coronary artery stent restenosis by 64-slice CT...
  96. doi Postsurgical spinal magnetic resonance imaging with iterative decomposition of water and fat with echo asymmetry and least-squares estimation
    Mizuho Murakami
    Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Comput Assist Tomogr 35:16-20. 2011
    ..However, the image quality often becomes poor because of artifacts from metal implants and/or from failed fat suppression, which obscure diagnosis...
  97. doi A comparative study of synchrony measures for the early diagnosis of Alzheimer's disease based on EEG
    J Dauwels
    Laboratory for Information and Decision Systems, Massachusetts Institute of Technology, Cambridge, MA, USA
    Neuroimage 49:668-93. 2010
    ..The classification performance may be further improved by adding complementary features from EEG; this approach may eventually lead to a reliable EEG-based diagnostic tool for MCI and AD...
  98. ncbi Field strength and diffusion encoding technique affect the apparent diffusion coefficient measurements in diffusion-weighted imaging of the abdomen
    Brian M Dale
    Siemens Healthcare, Cary, NC and daggerDepartment of Radiology, Duke University Medical Center, Durham, NC 27710, USA
    Invest Radiol 45:104-8. 2010
    ..The purpose of this study is to determine what effects a variety of diffusion encoding techniques at 1.5 T and 3 T have on measured abdominal apparent diffusion coefficient (ADC) values obtained in a healthy population...
  99. ncbi High-field diffusion MR histology: image-based correction of eddy-current ghosts in diffusion-weighted rapid acquisition with relaxation enhancement (DW-RARE)
    J Michael Tyszka
    Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
    Magn Reson Med 61:728-33. 2009
    ..Significant qualitative and quantitative ghost artifact reductions are demonstrated for individual DW and calculated diffusion tensor images...
  100. doi Ultrahigh-frequency EEG during fMRI: pushing the limits of imaging-artifact correction
    Frank Freyer
    Berlin NeuroImaging Center and Department of Neurology, Charite Universitaetsmedizin, Chariteplatz 1, 10117 Berlin, Germany
    Neuroimage 48:94-108. 2009
    Although solutions for imaging-artifact correction in simultaneous EEG-fMRI are improving, residual artifacts after correction still considerably affect the EEG spectrum in the ultrafast frequency band above 100 Hz...
  101. ncbi Independent component analysis using an extended infomax algorithm for mixed subgaussian and supergaussian sources
    T W Lee
    Computational Neurobiology Lab, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92038, USA
    Neural Comput 11:417-41. 1999
    ..Applied to high-dimensional data from electroencephalographic recordings, it is effective at separating artifacts such as eye blinks and line noise from weaker electrical signals that arise from sources in the brain.

Research Grants90

  1. Offset Astigmatic and Variable Focusing Collimation for Helical SPECT Brain Scans
    RONALD JASZCZAK; Fiscal Year: 2006
    ..when applied to brain imaging: i) The source distribution is not completely sampled, which results in image artifacts for axial source locations that are not near the collimator's central, transaxial (perpendicular) focal ..
  2. Harmonically detected swept source OCT
    Kristen Peterson; Fiscal Year: 2007
    ..optical coherence tomography by achieving noise-limited removal of the complex conjugate ambiguity and other artifacts. Our approach provides better artifact rejection ratios with simpler instrumentation than other methods...
  3. Time Resolved Cardiac Computed Tomography with Patient Dose Reduction
    Katsuyuki Taguchi; Fiscal Year: 2009
    ..Then, images are reconstructed by neglecting the cardiac motion within the time window resulting in blurring and artifacts in the reconstructed images...
  4. Near Term Development of Reagents and Enzymes for Genome Sequencing
    Steven A Benner; Fiscal Year: 2010
    ..multiplexed priming and PCR with primers having an effective length of 16mers (or longer) without creating PCR artifacts and supporting single nucleotide discrimination, (b) AEGIS tags appended to SAMRS primers that allow binning of ..
  5. Cardiac Physiology and Imaging Core for Mouse in Vivo
    Kirk Peterson; Fiscal Year: 2009
    ..to provide the greatest delineation between myocardium and blood, while not amplifying any oblique flow related artifacts. High resolution slices are readily obtainable in the mouse heart with the following prescription protocol: TR = ..
  6. Novel TIRF microscopy analyzing trafficking & signaling at the cell cortex
    Derek Toomre; Fiscal Year: 2009
    ..Consistent with the recovery act's goal, this funding will provide full-time summer employment for 4 undergraduate students and accelerate scientific achievement of the parent DP2 award...
  7. A Resource for magnetic resonance and optical imaging
    Ravinder Reddy; Fiscal Year: 2010
    ..The 3rd TR&D develops novel image reconstruction strategies to overcome artifacts due to motion and to quantify the rapid dynamics of contrast agents in cancer and to acquire dynamic ..
  8. Emergency Neurophysiological Assessment Bedside Logic Engine
    Don M Tucker; Fiscal Year: 2010
    ..recognition is required, yet in the past this has often failed to separate real neurological disorder from artifacts such as movement, eye blinks, and cardiac signals...
  9. Development & Malleability from Childhood to Adulthood
    Nicholas Ialongo; Fiscal Year: 2009
    ..data are thus likely to provide some of the best genomic controls currently possible to avoid stratification artifacts, the major problem with association genetic studies that might otherwise be a significant issue with the admixed ..
  10. Low-cost handheld medical device for neuroaxial anesthesia guidance in the obese
    FRANK WILLIAM MAULDIN; Fiscal Year: 2012
    ..over standard ultrasound due to reduced device cost, greater portability, and mitigation of off-axis reflection artifacts. In addition, this project includes an active shape model-based bone surface position estimation method for ..
  11. True Direct Single Molecule RNA Sequencing
    PATRICE MARIE MILOS; Fiscal Year: 2010
    ..This step has been shown to introduce many biases and artifacts. In order to best characterize the "true" transcriptome, we propose the application of single molecule, true ..
  12. Image-based modeling of nonlinear and anisotropic intervertebral disc mechanics
    Dawn Elliott; Fiscal Year: 2009
    ..Excising the tissue disrupts the fiber structure, which introduces artifacts into the material property measurement and does not represent the inhomogeneities that are reflected by the ..
  13. Image-based modeling of nonlinear and anisotropic intervertebral disc mechanics
    Edward J Vresilovic; Fiscal Year: 2010
    ..Excising the tissue disrupts the fiber structure, which introduces artifacts into the material property measurement and does not represent the inhomogeneities that are reflected by the ..
  14. Raman spectroscopy probes for assisting stereotactic breast biopsy needle placeme
    Stephen Fulghum; Fiscal Year: 2009
    ..to see because of dense breast tissue or the lesion may move from its expected position due to compression artifacts of the stereotactic targeting apparatus...
  15. Novel 3D Catheter Tracking System for Intracardiac Navigation
    DORON HARLEV; Fiscal Year: 2009
    ..limitations, including tracking distortions and inadequate correction for respiration and other motion artifacts. The potential consequences of inaccurate catheter tracking include ablation of electrically normal cardiac ..
  16. Deep Brain Stimulation in the Parkinsonian Monkey
    Jerrold L Vitek; Fiscal Year: 2010
    ..of DBS only after stimulation has been discontinued due to the problems associated with electrical stimulation artifacts. The results from many of these studies have been contradictory, likely secondary to the variety of conditions ..
  17. Deep Brain Stimulation in the Parkinsonian Monkey
    JERROLD VITEK; Fiscal Year: 2009
    ..of DBS only after stimulation has been discontinued due to the problems associated with electrical stimulation artifacts. The results from many of these studies have been contradictory, likely secondary to the variety of conditions ..
  18. Development of a 3D mammotomograph with novel techniques to overcome limitations
    RANDOLPH MCKINLEY; Fiscal Year: 2009
    ..yields morphological, pseudo-3D images (asymmetric volume image resolution with highly aliased and blurred artifacts) and with otherwise no quantifiable metrics due to the highly insufficiently sampled breast volume...
  19. Development of a 3D mammotomograph with novel techniques to overcome limitations
    Randolph L McKinley; Fiscal Year: 2010
    ..yields morphological, pseudo-3D images (asymmetric volume image resolution with highly aliased and blurred artifacts) and with otherwise no quantifiable metrics due to the highly insufficiently sampled breast volume...
  20. Functional brain imaging by laser-induced PAT
    Lihong Wang; Fiscal Year: 2005
    ..the proposed technology, functional photoacoustic tomography (fPAT), can image the intact brain free of speckle artifacts. Besides structural information, the proposed fPAT can also provide functional information including blood ..
  21. Functional brain imaging by laser-induced PAT
    Lihong Wang; Fiscal Year: 2004
    ..the proposed technology, functional photoacoustic tomography (fPAT), can image the intact brain free of speckle artifacts. Besides structural information, the proposed fPAT can also provide functional information including blood ..
  22. Functional brain imaging by laser-induced PAT
    Lihong Wang; Fiscal Year: 2007
    ..the proposed technology, functional photoacoustic tomography (fPAT), can image the intact brain free of speckle artifacts. Besides structural information, the proposed fPAT can also provide functional information including blood ..
  23. Functional brain imaging by laser-induced PAT
    Lihong Wang; Fiscal Year: 2006
    ..the proposed technology, functional photoacoustic tomography (fPAT), can image the intact brain free of speckle artifacts. Besides structural information, the proposed fPAT can also provide functional information including blood ..
  24. Functional brain imaging by laser-induced PAT
    Lihong Wang; Fiscal Year: 2006
    ..the proposed technology, functional photoacoustic tomography (fPAT), can image the intact brain free of speckle artifacts. Besides structural information, the proposed fPAT can also provide functional information including blood ..
  25. Functional brain imaging by laser-induced PAT
    Lihong Wang; Fiscal Year: 2003
    ..the proposed technology, functional photoacoustic tomography (fPAT), can image the intact brain free of speckle artifacts. Besides structural information, the proposed fPAT can also provide functional information including blood ..
  26. AFM AND STM IN NOVEL APPROACHES TO SEQUENCING
    Stuart Lindsay; Fiscal Year: 1993
    ..High resolution images are obtained. They are free from the artifacts that have plagued similar attempts to image DNA on graphite substrates...
  27. Multiphoton Fluorescence Lifetime Imaging of Solid Tumors Invivo
    V Krishnan Ramanujan; Fiscal Year: 2009
    ..lifetime is "intrinsic" to the fluorophore and its measurement is not affected by concentration and/or spectral artifacts as in intensity-based methods, (2) multiphoton excitation can enable increased tissue penetrability and reduced ..
  28. Development & Malleability from Childhood to Adulthood
    Nicholas S Ialongo; Fiscal Year: 2010
    ..data are thus likely to provide some of the best genomic controls currently possible to avoid stratification artifacts, the major problem with association genetic studies that might otherwise be a significant issue with the admixed ..
  29. Multiphoton Fluorescence Lifetime Imaging of Solid Tumors Invivo
    V Krishnan Ramanujan; Fiscal Year: 2010
    ..lifetime is "intrinsic" to the fluorophore and its measurement is not affected by concentration and/or spectral artifacts as in intensity-based methods, (2) multiphoton excitation can enable increased tissue penetrability and reduced ..
  30. An Advanced Technology Flat-Panel Imager for Fluoroscopy
    Larry Antonuk; Fiscal Year: 2009
    ..Secondly, AMFPIs are subject to image artifacts, originating from the trapping of charge in amorphous materials in the arrays...
  31. An Advanced Technology Flat-Panel Imager for Fluoroscopy
    Larry E Antonuk; Fiscal Year: 2010
    ..Secondly, AMFPIs are subject to image artifacts, originating from the trapping of charge in amorphous materials in the arrays...
  32. Engaging Tribal Participation in Research through Priority Setting and Regulation
    RON WHITENER; Fiscal Year: 2010
    ..and Native populations of the United States regarding the collection of Native American remains, cultural artifacts, and access to and use of natural resources, as well as health research...
  33. Late gadolinium enhancement cardiovascular MR for the Detection of Pre-Existent L
    Dana C Peters; Fiscal Year: 2010
    ..A time-study of scar enhancement after injection of contrast agent will discriminate between scar and image artifacts. Many AF patients are not in sinus-rhythm. We propose a method for reducing artifacts due to RR variability...
  34. A New Model for In Vivo Vestibular Pharmacology
    Larry F Hoffman; Fiscal Year: 2010
    ..Pilot studies have identified potential artifacts in afferent discharge that likely resulted from abrupt changes in perfusate pressure...
  35. Engaging Tribal Participation in Research through Priority Setting and Regulation
    RON WHITENER; Fiscal Year: 2009
    ..and Native populations of the United States regarding the collection of Native American remains, cultural artifacts, and access to and use of natural resources, as well as health research...
  36. Harmonically detected swept source OCT
    Kristen Peterson; Fiscal Year: 2009
    ..optical coherence tomography by achieving noise-limited removal of the complex conjugate ambiguity and other artifacts. Our approach provides better artifact rejection ratios with simpler instrumentation than other methods...
  37. Harmonically detected swept source OCT
    Kristen A Peterson; Fiscal Year: 2010
    ..optical coherence tomography by achieving noise-limited removal of the complex conjugate ambiguity and other artifacts. Our approach provides better artifact rejection ratios with simpler instrumentation than other methods...
  38. Harmonically detected swept source OCT
    Kristen A Peterson; Fiscal Year: 2011
    ..optical coherence tomography by achieving noise-limited removal of the complex conjugate ambiguity and other artifacts. Our approach provides better artifact rejection ratios with simpler instrumentation than other methods...
  39. The Endothelial Glycocalyx: Its Structure and Function and as a Mechanotransducer
    John M Tarbell; Fiscal Year: 2011
    ..Because of dehydration artifacts associated with conventional electron microscopy, even such rudimentary characteristics as the thickness of the ..
  40. The Endothelial Glycocalyx: Its Structure and Function and as a Mechanotransducer
    John M Tarbell; Fiscal Year: 2010
    ..Because of dehydration artifacts associated with conventional electron microscopy, even such rudimentary characteristics as the thickness of the ..
  41. BODY COMPOSITION AND MORTALITY POOLING PROJECT
    David Allison; Fiscal Year: 1999
    ..have suggested that the elevated risk of mortality with low BMI and the increase in the nadir with age are artifacts due to putative confounding variables such as smoking and preexisting "occult" disease...
  42. Functional characterization of pathways regulated by schizophrenia gene TCF4
    JOSEPH LOUIE MCCLAY; Fiscal Year: 2012
    ..Family-based designs preclude the possibility of artifacts due to population stratification...
  43. PATIENT MOTION DETECTION AND COMPENSATION IN SPECT
    Michael A King; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Patient motion is an ever-present potential cause of artifacts that can limit the accuracy of diagnostic imaging...
  44. Real-Time MRI Motion Correction System
    Roland Bammer; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): MOTIVATION - Motion remains one of the most frequent contributors to image artifacts in MR studies...
  45. Respiratory Motion-Reduced Cone-Beam CT Guidance of Radiotherapy in Lung & Liver
    Gikas Mageras; Fiscal Year: 2009
    ..We propose to develop and evaluate methods to reduce respiratory-induced motion artifacts in CBCT...
  46. MACHINE READABLE CATALOGING MEDICAL ARTIFACTS
    PATSY GERSTNER; Fiscal Year: 1990
    ..academic health sciences institutions, primarily libraries, to do on-line cataloguing of approximately 50,000 artifacts in their collections...
  47. A synchronized moving grid (SMOG) system to improve CBCT for IGRT and ART
    Jian Yue Jin; Fiscal Year: 2012
    ..direct scatter reduction methods is often limited, and although scatter correction methods can reduce scatter artifacts, they usually further degrade the contrast-to-noise ratio...
  48. Ultrasound Imaging of Breast by Use of a Hemispheric Array and Inverse Scattering
    ROBERT WAAG; Fiscal Year: 2009
    ..g., about two seconds, to avoid image-degrading motion artifacts. The planned use of off-line processing by available computing resources for image reconstruction circumvents ..
  49. Attomole-Level High-Throughput Genomics
    PATRICE MARIE MILOS; Fiscal Year: 2010
    ..and require multiple nucleic acid manipulation and amplification steps that are known to introduce biases and artifacts that confound downstream analyses and reduce/eliminate quantitative power...
  50. Ultrasound Imaging of Breast by Use of a Hemispheric Array and Inverse Scattering
    Robert C Waag; Fiscal Year: 2010
    ..g., about two seconds, to avoid image-degrading motion artifacts. The planned use of off-line processing by available computing resources for image reconstruction circumvents ..
  51. HIGH RESOLUTION MR ANGIOGRAPHY
    Dennis Parker; Fiscal Year: 2002
    ..RF imaging coils with the goal to further improve vascular detail, increase spatial resolution and decrease clip artifacts. First, we will evaluate sliding interleaved projection reconstruction (SLIPR) and a novel improvement to ..
  52. HIGH RESOLUTION MR ANGIOGRAPHY
    Dennis Parker; Fiscal Year: 2001
    ..RF imaging coils with the goal to further improve vascular detail, increase spatial resolution and decrease clip artifacts. First, we will evaluate sliding interleaved projection reconstruction (SLIPR) and a novel improvement to ..
  53. HIGH RESOLUTION MR ANGIOGRAPHY
    Dennis Parker; Fiscal Year: 2000
    ..RF imaging coils with the goal to further improve vascular detail, increase spatial resolution and decrease clip artifacts. First, we will evaluate sliding interleaved projection reconstruction (SLIPR) and a novel improvement to ..
  54. HIGH RESOLUTION MR ANGIOGRAPHY
    Dennis Parker; Fiscal Year: 1999
    ..RF imaging coils with the goal to further improve vascular detail, increase spatial resolution and decrease clip artifacts. First, we will evaluate sliding interleaved projection reconstruction (SLIPR) and a novel improvement to ..
  55. Novel Ether Containing Ligand Complexes: Cardiac Imaging
    KEVIN MARESCA; Fiscal Year: 2004
    ..and ischemia, the energy spectrum of thallium- 201 makes it particularly prone to soft tissue attenuation artifacts. While there are two FDA-approved Tc-99m perfusion tracers, having more favorable energy spectra for imaging, ..
  56. Motion-compensated PC HYPR VIPR for Renal MR Angiography
    Oliver Wieben; Fiscal Year: 2009
    ..Disadvantages of current phase contrast MRA approaches include inaccuracies and artifacts from intra-voxel dephasing and extensive scan times...
  57. Image mapped spectroscopy for snapshot 3-D biomedical imaging
    Mark Pierce; Fiscal Year: 2011
    ..sensitivity, increases system cost and complexity, and reduces image quality through the presence of motion artifacts. Here, we propose a method that for the first time will enable high-resolution snapshot 3-D optical imaging, ..
  58. Controlling for Endogeneity Biases in Estimating AA Effects on Drinking Outcomes
    Stephen Magura; Fiscal Year: 2009
    ..mainly correlational, studies of Alcoholics Anonymous (AA) effectiveness are susceptible to two main kinds of artifacts due to potential endogeneity bias in variables, defined as when variables treated as exogenous may actually be ..
  59. Controlling for Endogeneity Biases in Estimating AA Effects on Drinking Outcomes
    Stephen Magura; Fiscal Year: 2010
    ..mainly correlational, studies of Alcoholics Anonymous (AA) effectiveness are susceptible to two main kinds of artifacts due to potential endogeneity bias in variables, defined as when variables treated as exogenous may actually be ..
  60. ADDRESSING THE ISSUE OF GAP REGIONS IN GENOME SEQUENCING
    John SantaLucia; Fiscal Year: 2000
    ..Gap regions occur because of a variety of sequencing artifacts including mispriming of directed oligonucleotide primers, band-compressions in gel electrophoresis, and the ..
  61. ADDRESSING THE ISSUE OF GAP REGIONS IN GENOME SEQUENCING
    John SantaLucia; Fiscal Year: 1999
    ..Gap regions occur because of a variety of sequencing artifacts including mispriming of directed oligonucleotide primers, band-compressions in gel electrophoresis, and the ..
  62. ADDRESSING THE ISSUE OF GAP REGIONS IN GENOME SEQUENCING
    John SantaLucia; Fiscal Year: 2001
    ..Gap regions occur because of a variety of sequencing artifacts including mispriming of directed oligonucleotide primers, band-compressions in gel electrophoresis, and the ..
  63. HIGH RESOLUTION CONTRAST ENHANCED MR ANGIOGRAPHY
    Charles Mistretta; Fiscal Year: 2000
    ..Sparse sampling in X-ray computed tomography (CT) using filtered back projection (FBP) produces "clutter" artifacts which are large relative to the small differences in tissue attenuation displayed by CT...
  64. HIGH RESOLUTION CONTRAST ENHANCED MR ANGIOGRAPHY
    Charles Mistretta; Fiscal Year: 2001
    ..Sparse sampling in X-ray computed tomography (CT) using filtered back projection (FBP) produces "clutter" artifacts which are large relative to the small differences in tissue attenuation displayed by CT...
  65. HIGH RESOLUTION CONTRAST ENHANCED MR ANGIOGRAPHY
    Charles Mistretta; Fiscal Year: 1999
    ..Sparse sampling in X-ray computed tomography (CT) using filtered back projection (FBP) produces "clutter" artifacts which are large relative to the small differences in tissue attenuation displayed by CT...
  66. ENHANCED NAVIGATOR SPIRAL CORONARY MR ANGIOGRAPHY
    Yi Wang; Fiscal Year: 2002
    ..Aim 4. Implement and test contrast enhanced navigator spiral CMRA in an animal model. Imaging artifacts from cardiac and respiratory motion continue to be the major challenge for CMRA...
  67. Relationship of MRI to ASIA Impairment Scale in Chronic Spinal Cord Injury
    John McDonald; Fiscal Year: 2009
    ..from surrounding bone, respiratory and cardiovascular related motion and cerebrospinal fluid pulsation artifacts. Recently, investigators at the F.M...
  68. ENHANCED NAVIGATOR SPIRAL CORONARY MR ANGIOGRAPHY
    Yi Wang; Fiscal Year: 2001
    ..Aim 4. Implement and test contrast enhanced navigator spiral CMRA in an animal model. Imaging artifacts from cardiac and respiratory motion continue to be the major challenge for CMRA...
  69. Shared Instrumentation: Vevo 770 Ultrasound System
    David Pollock; Fiscal Year: 2009
    ..Finally, all projects will need to use the in vivo rail system for reducing movement artifacts and maintaining health of the animals during imaging...
  70. ENHANCED NAVIGATOR SPIRAL CORONARY MR ANGIOGRAPHY
    Yi Wang; Fiscal Year: 2003
    ..Aim 4. Implement and test contrast enhanced navigator spiral CMRA in an animal model. Imaging artifacts from cardiac and respiratory motion continue to be the major challenge for CMRA...
  71. ENHANCED NAVIGATOR SPIRAL CORONARY MR ANGIOGRAPHY
    Yi Wang; Fiscal Year: 2000
    ..Aim 4. Implement and test contrast enhanced navigator spiral CMRA in an animal model. Imaging artifacts from cardiac and respiratory motion continue to be the major challenge for CMRA...
  72. Near Term Development of Reagents and Enzymes for Genome Sequencing
    Steven Benner; Fiscal Year: 2009
    ..multiplexed priming and PCR with primers having an effective length of 16mers (or longer) without creating PCR artifacts and supporting single nucleotide discrimination, (b) AEGIS tags appended to SAMRS primers that allow binning of ..
  73. VISUAL ENVIRONMENT FOR MULTI SCALE BIOMOLEC MODEL: PROTEIN STRUCT, DRUG DESIGN
    Arthur Olson; Fiscal Year: 2000
    ..These initial studies indicate that the iterative methods can produce superior reconstructions with fewer artifacts in comparison to the R-weighted algorithm. These evaluations are continuing...
  74. VISUAL ENVIRONMENT FOR MULTI SCALE BIOMOLEC MODEL: PROTEIN STRUCT, DRUG DESIGN
    Arthur Olson; Fiscal Year: 2001
    ..These initial studies indicate that the iterative methods can produce superior reconstructions with fewer artifacts in comparison to the R-weighted algorithm. These evaluations are continuing...
  75. VISUAL ENVIRONMENT FOR MULTI SCALE BIOMOLEC MODEL: PROTEIN STRUCT, DRUG DESIGN
    Arthur Olson; Fiscal Year: 1999
    ..These initial studies indicate that the iterative methods can produce superior reconstructions with fewer artifacts in comparison to the R-weighted algorithm. These evaluations are continuing...
  76. Offset Astigmatic and Variable Focusing Collimation for Helical SPECT Brain Scans
    RONALD JASZCZAK; Fiscal Year: 2007
    ..when applied to brain imaging: i) The source distribution is not completely sampled, which results in image artifacts for axial source locations that are not near the collimator's central, transaxial (perpendicular) focal ..
  77. Near Term Development of Reagents and Enzymes for Genome Sequencing
    Steven Benner; Fiscal Year: 2009
    ..multiplexed priming and PCR with primers having an effective length of 16mers (or longer) without creating PCR artifacts and supporting single nucleotide discrimination, (b) AEGIS tags appended to SAMRS primers that allow binning of ..
  78. Time Resolved Cardiac Computed Tomography with Patient Dose Reduction
    Katsuyuki Taguchi; Fiscal Year: 2009
    ..Then, images are reconstructed by neglecting the cardiac motion within the time window resulting in blurring and artifacts in the reconstructed images...
  79. INTERVENTIONAL DEVICE IMAGING: MRI OF CANCER FOR BIOPSY
    R Butts; Fiscal Year: 2000
    ..Efforts to improve image quality have focused on designing interventional device materials that produce minimal artifacts with conventional imaging methods...
  80. Software Systems for Detecting Rare Muations
    Todd Smith; Fiscal Year: 2009
    ..relative to control sequences, with respect to sequence contexts, random noise, laboratory steps, and instrument artifacts. The catalogs will then be used to develop statistical algorithms that can analyze large numbers of aligned ..
  81. Electron Tomography of the Outer Hair Cell Lateral Wall
    WILLIAM TRIFFO; Fiscal Year: 2007
    ..wall structure has been limited to extrapolation from 2D studies of samples, further complicated by preservation artifacts depending on the sample preparation method used...
  82. Real-Time MRI Motion Correction System
    Roland Bammer; Fiscal Year: 2007
    ..DESCRIPTION (provided by applicant): MOTIVATION - Motion remains one of the most frequent contributors to image artifacts in MR studies...
  83. Electron Tomography of the Outer Hair Cell Lateral Wall
    WILLIAM TRIFFO; Fiscal Year: 2009
    ..wall structure has been limited to extrapolation from 2D studies of samples, further complicated by preservation artifacts depending on the sample preparation method used...
  84. Quantitative periprosthetic PET/CT
    Thomas Lang; Fiscal Year: 2009
    ..However, CT suffers from severe image artifacts in the presence of metallic implants that not only render the CT images undiagnostic but also negatively ..
  85. Promiscuous and Specific Inhibitors of Cruzain
    Brian Shoichet; Fiscal Year: 2007
    ..Multiple mechanisms have been proposed to explain these artifacts, including chemical reactivity, oxidation, assay interference, and colloidal aggregation...
  86. Respiratory Motion-Reduced Cone-Beam CT Guidance of Radiotherapy in Lung & Liver
    Gikas S Mageras; Fiscal Year: 2010
    ..We propose to develop and evaluate methods to reduce respiratory-induced motion artifacts in CBCT...
  87. Respiratory Motion-Reduced Cone-Beam CT Guidance of Radiotherapy in Lung & Liver
    Gikas Mageras; Fiscal Year: 2009
    ..We propose to develop and evaluate methods to reduce respiratory-induced motion artifacts in CBCT...
  88. Development of Methods and Software for Interior Tomography Applications
    Hengyong Yu; Fiscal Year: 2009
    ..When applying conventional CT algorithms to such an incomplete dataset, the features outside the ROI may create artifacts overlapping inside real features...
  89. Development of a Brain Template for Diffusion-Tensor MRI
    Konstantinos Arfanakis; Fiscal Year: 2009
    ..DTI data acquisitions are based on echo- planar imaging (EPI), which suffers from distortions and image artifacts. Furthermore, to increase the accuracy of normalization, all the information of the tensor must be used in the ..