artifacts

Summary

Summary: Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.

Top Publications

  1. ncbi Image distortion correction in fMRI: A quantitative evaluation
    Chloe Hutton
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London WCIN 3BG, United Kingdom
    Neuroimage 16:217-40. 2002
  2. ncbi Removing electroencephalographic artifacts by blind source separation
    T P Jung
    Howard Hughes Medical Institute, Salk Institute, San Diego, California, USA
    Psychophysiology 37:163-78. 2000
  3. ncbi Image-based method for retrospective correction of physiological motion effects in fMRI: RETROICOR
    G H Glover
    Department of Radiology, Stanford University School of Medicine, Center for Advanced MR Technology at Stanford, Stanford, California, USA
    Magn Reson Med 44:162-7. 2000
  4. ncbi PCR-induced sequence artifacts and bias: insights from comparison of two 16S rRNA clone libraries constructed from the same sample
    Silvia G Acinas
    Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Appl Environ Microbiol 71:8966-9. 2005
  5. ncbi Removal of eye activity artifacts from visual event-related potentials in normal and clinical subjects
    T P Jung
    University of California, San Diego, La Jolla, CA 92093, USA
    Clin Neurophysiol 111:1745-58. 2000
  6. ncbi Overcoming artifacts from metallic orthopedic implants at high-field-strength MR imaging and multi-detector CT
    Mi Jung Lee
    Department of Diagnostic Radiology and Research Institute of Radiological Science and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 134 Sincheon Dong Seodaemun Gu, Seoul 120 752, Republic of Korea
    Radiographics 27:791-803. 2007
  7. ncbi Heteroduplexes in mixed-template amplifications: formation, consequence and elimination by 'reconditioning PCR'
    Janelle R Thompson
    Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, Cambridge, MA 02139, USA
    Nucleic Acids Res 30:2083-8. 2002
  8. ncbi DNA sequences from multiple amplifications reveal artifacts induced by cytosine deamination in ancient DNA
    M Hofreiter
    Max Planck Institute for Evolutionary Anthropology, Inselstrasse 22, D-04103 Leipzig, Germany
    Nucleic Acids Res 29:4793-9. 2001
  9. ncbi Reducing the effects of PCR amplification and sequencing artifacts on 16S rRNA-based studies
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 6:e27310. 2011
  10. ncbi fMRI in the presence of task-correlated breathing variations
    Rasmus M Birn
    Laboratory of Brain and Cognition, National Institute of Mental Health, NIH, 10 Center Dr, Bldg 10, Rm 1D80, Bethesda, MD 20892 1148, USA
    Neuroimage 47:1092-104. 2009

Research Grants

  1. Offset Astigmatic and Variable Focusing Collimation for Helical SPECT Brain Scans
    RONALD JASZCZAK; Fiscal Year: 2006
  2. Harmonically detected swept source OCT
    Kristen Peterson; Fiscal Year: 2007
  3. Time Resolved Cardiac Computed Tomography with Patient Dose Reduction
    Katsuyuki Taguchi; Fiscal Year: 2009
  4. Near Term Development of Reagents and Enzymes for Genome Sequencing
    Steven A Benner; Fiscal Year: 2010
  5. True Direct Single Molecule RNA Sequencing
    PATRICE MARIE MILOS; Fiscal Year: 2010
  6. Deep Brain Stimulation in the Parkinsonian Monkey
    JERROLD VITEK; Fiscal Year: 2009
  7. Deep Brain Stimulation in the Parkinsonian Monkey
    Jerrold L Vitek; Fiscal Year: 2010
  8. Functional brain imaging by laser-induced PAT
    Lihong Wang; Fiscal Year: 2006
  9. Functional brain imaging by laser-induced PAT
    Lihong Wang; Fiscal Year: 2007
  10. An Advanced Technology Flat-Panel Imager for Fluoroscopy
    Larry E Antonuk; Fiscal Year: 2010

Detail Information

Publications311 found, 100 shown here

  1. ncbi Image distortion correction in fMRI: A quantitative evaluation
    Chloe Hutton
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London WCIN 3BG, United Kingdom
    Neuroimage 16:217-40. 2002
    ..but requires postprocessing to improve the robustness of the acquired field map and reduce any secondary artifacts. Furthermore, the distribution of the internal magnetic field throughout the head is position dependent ..
  2. ncbi Removing electroencephalographic artifacts by blind source separation
    T P Jung
    Howard Hughes Medical Institute, Salk Institute, San Diego, California, USA
    Psychophysiology 37:163-78. 2000
    ..Many methods have been proposed to remove artifacts from EEG recordings, especially those arising from eye movements and blinks...
  3. ncbi Image-based method for retrospective correction of physiological motion effects in fMRI: RETROICOR
    G H Glover
    Department of Radiology, Stanford University School of Medicine, Center for Advanced MR Technology at Stanford, Stanford, California, USA
    Magn Reson Med 44:162-7. 2000
    ..The method is found to perform well for both respiration- and cardiac-induced noise without imposing spatial filtering on the correction. Magn Reson Med 44:162-167, 2000...
  4. ncbi PCR-induced sequence artifacts and bias: insights from comparison of two 16S rRNA clone libraries constructed from the same sample
    Silvia G Acinas
    Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Appl Environ Microbiol 71:8966-9. 2005
    The contribution of PCR artifacts to 16S rRNA gene sequence diversity from a complex bacterioplankton sample was estimated...
  5. ncbi Removal of eye activity artifacts from visual event-related potentials in normal and clinical subjects
    T P Jung
    University of California, San Diego, La Jolla, CA 92093, USA
    Clin Neurophysiol 111:1745-58. 2000
    ..Often, all epochs contaminated by large eye artifacts are rejected as unusable, though this may prove unacceptable when blinks and eye movements occur frequently.
  6. ncbi Overcoming artifacts from metallic orthopedic implants at high-field-strength MR imaging and multi-detector CT
    Mi Jung Lee
    Department of Diagnostic Radiology and Research Institute of Radiological Science and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 134 Sincheon Dong Seodaemun Gu, Seoul 120 752, Republic of Korea
    Radiographics 27:791-803. 2007
    At magnetic resonance (MR) imaging and multidetector computed tomography (CT), artifacts arising from metallic orthopedic hardware are an obstacle to obtaining optimal images...
  7. ncbi Heteroduplexes in mixed-template amplifications: formation, consequence and elimination by 'reconditioning PCR'
    Janelle R Thompson
    Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, Cambridge, MA 02139, USA
    Nucleic Acids Res 30:2083-8. 2002
    Although it has been recognized that PCR amplification of mixed templates may generate sequence artifacts, the mechanisms of their formation, frequency and potential elimination have not been fully elucidated...
  8. ncbi DNA sequences from multiple amplifications reveal artifacts induced by cytosine deamination in ancient DNA
    M Hofreiter
    Max Planck Institute for Evolutionary Anthropology, Inselstrasse 22, D-04103 Leipzig, Germany
    Nucleic Acids Res 29:4793-9. 2001
    ..1% even under the unlikely scenario where each amplification starts from a single template molecule...
  9. ncbi Reducing the effects of PCR amplification and sequencing artifacts on 16S rRNA-based studies
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 6:e27310. 2011
    ....
  10. ncbi fMRI in the presence of task-correlated breathing variations
    Rasmus M Birn
    Laboratory of Brain and Cognition, National Institute of Mental Health, NIH, 10 Center Dr, Bldg 10, Rm 1D80, Bethesda, MD 20892 1148, USA
    Neuroimage 47:1092-104. 2009
    ....
  11. ncbi 3.0 T vs. 1.5 T MR angiography: in vitro comparison of intravascular stent artifacts
    Alexander Wall
    Department of Clinical Radiology, University of Munster, Munster, Germany
    J Magn Reson Imaging 22:772-9. 2005
    ..To evaluate the signal characteristics of different iliac artery stents in MR angiography (MRA) at 3 T in comparison with 1.5 T...
  12. ncbi Spiral-in/out BOLD fMRI for increased SNR and reduced susceptibility artifacts
    G H Glover
    Department of Radiology, Center for Advanced MR Technology, Stanford University School of Medicine, Stanford, California 94305 5488, USA
    Magn Reson Med 46:515-22. 2001
    ..be combined in several ways to simultaneously achieve increased signal-to-noise ratio (SNR) and reduced dropout artifacts. Activation experiments employing an olfaction task demonstrate significantly increased activation volumes due ..
  13. ncbi ChIP on Chip: surprising results are often artifacts
    Torsten Waldminghaus
    Department of Cell Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital and University of Oslo, 0310 Oslo, Norway
    BMC Genomics 11:414. 2010
    ..The method of chromatin immunoprecipitation combined with microarrays (ChIP-Chip) is a powerful tool for genome-wide analysis of protein binding. However, a high background signal is a common phenomenon...
  14. ncbi Multidetector-row computed tomography imaging characteristics of mechanical prosthetic valves
    Petr Symersky
    Department of Cardiothoracic Surgery, Isala Klinieken Zwolle, The Netherlands
    J Heart Valve Dis 20:216-22. 2011
    ..A pulsatile in vitro model was developed to study the MDCT imaging characteristics of mechanical heart valves (MHVs)...
  15. ncbi Comparison of principal and independent component analysis in removing extracerebral interference from near-infrared spectroscopy signals
    Jaakko Virtanen
    Helsinki University of Technology, Department of Biomedical Engineering and Computational Science, P O Box 3310, FI 02015 TKK, Helsinki, Finland
    J Biomed Opt 14:054032. 2009
    ..Performance differences between PCA and ICA could be attributed primarily to different criteria for identifying the surface effect...
  16. ncbi Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations--many questions, some answers
    Robert Landsiedel
    Department of Product Safety, BASF SE, 67056 Ludwigshafen, Germany
    Mutat Res 681:241-58. 2009
    ..This review should help to improve standard genotoxicity testing as well as investigations on the underlying mechanism and the interpretation of genotoxicity data on nanomaterials...
  17. ncbi Suppression of metal artifacts in CT using a reconstruction procedure that combines MAP and projection completion
    Catherine Lemmens
    Department of Nuclear Medicine, K U Leuven, B 3000 Leuven, Belgium
    IEEE Trans Med Imaging 28:250-60. 2009
    Metal implants such as hip prostheses and dental fillings produce streak and star artifacts in the reconstructed computed tomography (CT) images. Due to these artifacts, the CT image may not be diagnostically usable...
  18. ncbi Diffusion imaging in humans at 7T using readout-segmented EPI and GRAPPA
    Robin M Heidemann
    Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
    Magn Reson Med 64:9-14. 2010
    ..Readout-segmented echo-planar imaging in conjunction with parallel imaging has the potential to reduce these artifacts by allowing a further reduction in effective echo spacing during the echo-planar imaging readout...
  19. ncbi Identification and correction of abnormal, incomplete and mispredicted proteins in public databases
    Alinda Nagy
    Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, H 1113 Budapest, Hungary
    BMC Bioinformatics 9:353. 2008
    ....
  20. ncbi Validation of ICA as a tool to remove eye movement artifacts from EEG/ERP
    Maarten Mennes
    Department of Woman and Child, KU Leuven, Leuven, Belgium
    Psychophysiology 47:1142-50. 2010
    Eye movement artifacts in electroencephalogram (EEG) recordings can greatly distort grand mean event-related potential (ERP) waveforms. Different techniques have been suggested to remove these artifacts prior to ERP analysis...
  21. ncbi In vitro evaluation of intravascular stent artifacts in three-dimensional MR angiography
    D Maintz
    Department of Diagnostic Radiology, University of Cologne, School of Medicine, Cologne, Germany
    Invest Radiol 36:218-24. 2001
    ..To evaluate the intraluminal signal characteristics of various stents and stent-grafts in contrast-enhanced three-dimensional MR angiography (3D MRA) in vitro...
  22. ncbi Physiological noise and signal-to-noise ratio in fMRI with multi-channel array coils
    Christina Triantafyllou
    Athinoula A Martinos Imaging Center at McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Neuroimage 55:597-606. 2011
    ..At higher acceleration factors, image SNR is reduced and the time-series becomes increasingly thermal noise dominant. However, the tSNR reduction is smaller than the reduction in image SNR due to the presence of physiological noise...
  23. ncbi Influence of heart rate on the BOLD signal: the cardiac response function
    Catie Chang
    Department of Electrical Engineering, Stanford University, Lucas MRI S Center, Stanford, CA 94305 5488, USA
    Neuroimage 44:857-69. 2009
    ..s previously-described respiration response function. Furthermore, it is shown that modeling out RV and HR can significantly alter functional connectivity maps of the default-mode network...
  24. ncbi EMG and EOG artifacts in brain computer interface systems: A survey
    Mehrdad Fatourechi
    Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada V6T 1Z4
    Clin Neurophysiol 118:480-94. 2007
    ..b>Artifacts are undesirable signals that can interfere with neurological phenomena...
  25. ncbi Comparison of detrending methods for optimal fMRI preprocessing
    Jody Tanabe
    Department of Radiology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Neuroimage 15:902-7. 2002
    ..However, auto-detrending (selecting the best algorithm or none, if detrending is not useful) appears to be the most judicious choice, particularly for analyzing fMRI data with weak activations in the presence of baseline drift...
  26. ncbi MR imaging of vascular stents: effects of susceptibility, flow, and radiofrequency eddy currents
    L W Bartels
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan, The Netherlands
    J Vasc Interv Radiol 12:365-71. 2001
    The purpose of this in vitro study was to examine the various sources of artifacts in magnetic resonance (MR) imaging and angiography of vascular stents.
  27. ncbi Local noise weighted filtering for emphysema scoring of low-dose CT images
    Arnold M R Schilham
    Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 25:451-63. 2006
    ..NOVA filtering of a CT image of typically 400 x 512 x 512 voxels takes only a couple of minutes which makes it suitable for routine use in clinical practice...
  28. ncbi Measuring rDNA diversity in eukaryotic microbial systems: how intragenomic variation, pseudogenes, and PCR artifacts confound biodiversity estimates
    Daniel J Thornhill
    Department of Biological Sciences, Auburn University, 101 Rouse Life Sciences Building, Auburn, Alabama 36849, USA
    Mol Ecol 16:5326-40. 2007
    ..These considerations must be taken into account when interpreting sequence data generated by bacterial cloning of multicopy genes such as rDNA...
  29. ncbi AAPM/RSNA physics tutorial for residents: MR artifacts, safety, and quality control
    Jiachen Zhuo
    Department of Radiology, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201, USA
    Radiographics 26:275-97. 2006
    b>Artifacts in magnetic resonance (MR) imaging result from the complex interaction of contemporary imager subsystems, including the main magnet, gradient coils, radiofrequency (RF) transmitter and receiver, and reconstruction algorithm ..
  30. ncbi Detection of sonographic B-lines in patients with normal lung or radiographic alveolar consolidation
    Giovanni Volpicelli
    Department of Emergency Medicine, San Luigi Gonzaga Hospital, Torino, Italy
    Med Sci Monit 14:CR122-8. 2008
    Diffuse comet-tail B-line artifacts in lung ultrasound are a sign of alveolar-interstitial syndrome, but isolated transthoracic scans positive for B-lines (multiple B lines or B+) could be detected in other conditions...
  31. ncbi Neurophysiological predictor of SMR-based BCI performance
    Benjamin Blankertz
    Machine Learning Laboratory, Berlin Institute of Technology, Germany
    Neuroimage 51:1303-9. 2010
    ....
  32. ncbi High-resolution maps of magnetization transfer with inherent correction for RF inhomogeneity and T1 relaxation obtained from 3D FLASH MRI
    Gunther Helms
    MR Forschung in der Neurologie und Psychiatrie, Universitatsmedizin Gottingen, Gottingen, Germany
    Magn Reson Med 60:1396-407. 2008
    ..It is inherently compensated for inhomogeneities of receive and transmit RF fields. The MT saturation appeared to be a sensitive parameter to depict MS lesions and alterations of normal-appearing white matter...
  33. ncbi High resolution single-shot EPI at 7T
    Oliver Speck
    Department of Biomedical Magnetic Resonance, Faculty of Natural Sciences Institute for Experimental Physics, Otto von Guericke University Magdeburg, Leipziger Str 44, Haus 01, 39120 Magdeburg, Germany
    MAGMA 21:73-86. 2008
    ..This study developed and tested pulse sequence and protocol modifications required to allow high resolution EPI for whole brain functional neuroimaging...
  34. ncbi Automatic correction of ocular artifacts in the EEG: a comparison of regression-based and component-based methods
    Garrick L Wallstrom
    Center for Biomedical Informatics, University of Pittsburgh, Forbes Tower Suite 8084, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Int J Psychophysiol 53:105-19. 2004
    A variety of procedures have been proposed to correct ocular artifacts in the electroencephalogram (EEG), including methods based on regression, principal components analysis (PCA) and independent component analysis (ICA)...
  35. ncbi Ultrasound diagnosis of occult pneumothorax
    Daniel A Lichtenstein
    Medical Intensive Care Unit, , Boulogne (Paris-Ouest, France
    Crit Care Med 33:1231-8. 2005
    ..The lung point had a sensitivity of 79% and a specificity of 100%. CONCLUSIONS: For the diagnosis of occult pneumothorax, ultrasound can decrease the need for computed tomography...
  36. ncbi Molecular dynamics simulations of lipid bilayers: major artifacts due to truncating electrostatic interactions
    M Patra
    Biophysics and Statistical Mechanics Group, Laboratory of Computational Engineering, Helsinki University of Technology, FIN-02015 HUT, Finland
    Biophys J 84:3636-45. 2003
    ..The results obtained using PME, on the other hand, are consistent with experiments. These artifacts are interpreted in terms of radial distribution functions g(r) of molecules and molecular groups in the bilayer ..
  37. ncbi Phase-sensitive inversion recovery for detecting myocardial infarction using gadolinium-delayed hyperenhancement
    Peter Kellman
    Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, Maryland 20892-1061, USA
    Magn Reson Med 47:372-83. 2002
    ..Phase-sensitive detection also has the advantage of decreasing the sensitivity to changes in tissue T(1) with increasing delay from contrast agent injection...
  38. ncbi Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI
    Rasmus M Birn
    Laboratory of Brain and Cognition, National Institute of Mental Health, NIH, 10 Center Dr, Bldg 10, Rm 1D80 Bethesda, MD 20892 1148, USA
    Neuroimage 31:1536-48. 2006
    ..Regressing out global signal changes or cueing the subject to breathe at a constant rate and depth resulted in an improved spatial overlap between deactivations and resting-state correlations among areas that showed deactivation...
  39. ncbi Analysis and visualization of single-trial event-related potentials
    T P Jung
    Institute for Neural Computation, University of California San Diego, La Jolla, California 92093 0523, USA
    Hum Brain Mapp 14:166-85. 2001
    ..plus 22 neurological patients whose EEG records were heavily contaminated with blink and other eye-movement artifacts. Results show that ICA can separate artifactual, stimulus-locked, response-locked, and non-event-related ..
  40. ncbi Metastatic colorectal cancer KRAS genotyping in routine practice: results and pitfalls
    Aude Lamy
    Laboratory of Tumor Genetics, University Hospital, Rouen, France
    Mod Pathol 24:1090-100. 2011
    ..The tumor heterogeneity observed in some patients indicates that it should be more appropriate to perform KRAS genotyping on metastases if sample is available...
  41. ncbi Rejection of pulse related artefact (PRA) from continuous electroencephalographic (EEG) time series recorded during functional magnetic resonance imaging (fMRI) using constraint independent component analysis (cICA)
    Yves Leclercq
    Cyclotron Research Centre, University of Liege, Belgium
    Neuroimage 44:679-91. 2009
    ..Using multichannel EEG recordings obtained in a 3 T MR scanner, with and without concomitant fMRI acquisition, we provide evidence for the sensitivity and specificity of the method in rejecting PRA in various sleep and waking conditions...
  42. ncbi Physiological recordings: basic concepts and implementation during functional magnetic resonance imaging
    Marcus A Gray
    Clinical Imaging Sciences Centre and Department of Psychiatry, Brighton and Sussex Medical School, University of Sussex, Falmer Campus, UK
    Neuroimage 47:1105-15. 2009
    ..We review the sources of these potential problems and the current approaches and advice to enable the combination of fMRI and physiological monitoring in a safe and effective manner...
  43. ncbi Metal-related artifacts in instrumented spine. Techniques for reducing artifacts in CT and MRI: state of the art
    P Stradiotti
    IRCCS Istituto Ortopedico Galeazzi, Via R Galeazzi 4, Milan 20161, Italy
    Eur Spine J 18:102-8. 2009
    ..MRI and CT imaging can be more helpful, using cross-sectional view. However, the presence of metal-related artifacts at both conventional CT and MRI imaging can obscure relevant anatomy and disease...
  44. ncbi A component based noise correction method (CompCor) for BOLD and perfusion based fMRI
    Yashar Behzadi
    UCSD Center for Functional Magnetic Resonance Imaging and Department of Radiology, 9500 Gilman Drive, MC 0677, La Jolla, CA 92093 0677, USA
    Neuroimage 37:90-101. 2007
    ..In comparison to RETROICOR, CompCor has the advantage of not requiring external monitoring of physiological fluctuations...
  45. ncbi High-field diffusion MR histology: image-based correction of eddy-current ghosts in diffusion-weighted rapid acquisition with relaxation enhancement (DW-RARE)
    J Michael Tyszka
    Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
    Magn Reson Med 61:728-33. 2009
    ..Significant qualitative and quantitative ghost artifact reductions are demonstrated for individual DW and calculated diffusion tensor images...
  46. ncbi Antisense transcripts of V(D)J rearrangements; artifacts caused by false priming?
    Yuan Zhao
    Department of Immunobiology, King s College London, Guy s Hospital Campus, St Thomas St, London SE1 9RT, UK
    Mol Immunol 46:2357-62. 2009
    ....
  47. ncbi US artifacts
    Myra K Feldman
    Department of Radiology, Western Pennsylvania Hospital, 4800 Friendship Ave, Pittsburgh, PA 15224, USA
    Radiographics 29:1179-89. 2009
    Image artifacts are commonly encountered in clinical ultrasonography (US) and may be a source of confusion for the interpreting physician. Some artifacts may be avoidable and arise secondary to improper scanning technique...
  48. ncbi A comparative study of synchrony measures for the early diagnosis of Alzheimer's disease based on EEG
    J Dauwels
    Laboratory for Information and Decision Systems, Massachusetts Institute of Technology, Cambridge, MA, USA
    Neuroimage 49:668-93. 2010
    ..The classification performance may be further improved by adding complementary features from EEG; this approach may eventually lead to a reliable EEG-based diagnostic tool for MCI and AD...
  49. ncbi Ultrahigh-frequency EEG during fMRI: pushing the limits of imaging-artifact correction
    Frank Freyer
    Berlin NeuroImaging Center and Department of Neurology, Charite Universitaetsmedizin, Chariteplatz 1, 10117 Berlin, Germany
    Neuroimage 48:94-108. 2009
    Although solutions for imaging-artifact correction in simultaneous EEG-fMRI are improving, residual artifacts after correction still considerably affect the EEG spectrum in the ultrafast frequency band above 100 Hz...
  50. ncbi Semi-automatic identification of independent components representing EEG artifact
    Filipa Campos Viola
    MRC Institute of Hearing Research, Southampton, UK
    Clin Neurophysiol 120:868-77. 2009
    ..component analysis (ICA) can disentangle multi-channel electroencephalogram (EEG) signals into a number of artifacts and brain-related signals...
  51. ncbi Image reconstruction in circular cone-beam computed tomography by constrained, total-variation minimization
    Emil Y Sidky
    Department of Radiology MC 2026, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Phys Med Biol 53:4777-807. 2008
    ..It appears to be robust against cone-beam artifacts, and may be particularly useful when the angular range is limited or when the angular sampling rate is low...
  52. ncbi How to perform an accurate assessment of cardiac function in mice using high-resolution magnetic resonance imaging
    Jurgen E Schneider
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, UK
    J Cardiovasc Magn Reson 8:693-701. 2006
    ..Here, we describe a protocol that allows for a quick and reproducible approach of obtaining the relevant cardiac views for cine-MRI, and we explain how an accurate experimental image analysis can be performed...
  53. ncbi Field strength and diffusion encoding technique affect the apparent diffusion coefficient measurements in diffusion-weighted imaging of the abdomen
    Brian M Dale
    Siemens Healthcare, Cary, NC and daggerDepartment of Radiology, Duke University Medical Center, Durham, NC 27710, USA
    Invest Radiol 45:104-8. 2010
    ..The purpose of this study is to determine what effects a variety of diffusion encoding techniques at 1.5 T and 3 T have on measured abdominal apparent diffusion coefficient (ADC) values obtained in a healthy population...
  54. ncbi Optimisation of the 3D MDEFT sequence for anatomical brain imaging: technical implications at 1.5 and 3 T
    R Deichmann
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London WC1N 3BG, UK
    Neuroimage 21:757-67. 2004
    ..It is shown both theoretically and experimentally that these problems can be avoided by using spin tagging and fat saturation...
  55. ncbi Postsurgical spinal magnetic resonance imaging with iterative decomposition of water and fat with echo asymmetry and least-squares estimation
    Mizuho Murakami
    Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Comput Assist Tomogr 35:16-20. 2011
    ..However, the image quality often becomes poor because of artifacts from metal implants and/or from failed fat suppression, which obscure diagnosis...
  56. ncbi Validation of ICA-based myogenic artifact correction for scalp and source-localized EEG
    Brenton W McMenamin
    Department of Psychology, Center for Cognitive Science, University of Minnesota, Twin Cities, Minneapolis, MN, USA
    Neuroimage 49:2416-32. 2010
    ..In light of these results, several practical suggestions and recommendations are made for intelligently using ICA to minimize EMG and other common artifacts.
  57. ncbi Development and validation of segmentation and interpolation techniques in sinograms for metal artifact suppression in CT
    Wouter J H Veldkamp
    Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Med Phys 37:620-8. 2010
    Metal prostheses cause artifacts in computed tomography (CT) images...
  58. ncbi Evaluation of coronary artery in-stent restenosis with prospectively ECG-triggered axial CT angiography versus retrospective technique: a phantom study
    W J Yang
    Department of Radiology, Rui Jin Hospital, Medical School, Shanghai Jiao Tong University, No 197, Rui Jin Er Road, Shanghai, 200025, China
    Radiol Med 116:189-96. 2011
    ..This study compared the performance of prospectively electrocardiographically (ECG)-triggered axial computed tomography (CT) angiography with retrospective technique in evaluating coronary artery stent restenosis by 64-slice CT...
  59. ncbi Synchronization of neuronal activity in the human primary motor cortex by transcranial magnetic stimulation: an EEG study
    T Paus
    Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada
    J Neurophysiol 86:1983-90. 2001
    ..As such, they corroborate previous studies of cortical oscillations in the motor cortex and point to the potential of the combined TMS/EEG approach for further investigations of cortical rhythms in the human brain...
  60. ncbi Visual inspection of independent components: defining a procedure for artifact removal from fMRI data
    Robert E Kelly
    Weill Cornell Institute of Geriatric Psychiatry, Weill Cornell Medical College, 21 Bloomingdale Road, White Plains, NY 10605, USA
    J Neurosci Methods 189:233-45. 2010
    b>Artifacts in functional magnetic resonance imaging (fMRI) data, primarily those related to motion and physiological sources, negatively impact the functional signal-to-noise ratio in fMRI studies, even after conventional fMRI ..
  61. ncbi Algorithm-driven artifacts in median Polish summarization of microarray data
    Federico M Giorgi
    Max Planck Institute of Molecular Plant Physiology, Am Muehlenberg 1, 14476 Golm, Germany
    BMC Bioinformatics 11:553. 2010
    ....
  62. ncbi Reducing chimera formation during PCR amplification to ensure accurate genotyping
    R P Smyth
    Centre for Virology, Burnet Institute, 85 Commercial Road, Melbourne, Victoria, Australia
    Gene 469:45-51. 2010
    ..This procedure will facilitate the generation of data sets that more accurately reflect the underlying population diversity rather than artifacts introduced by the process itself.
  63. ncbi Removal of magnetoencephalographic artifacts with temporal signal-space separation: demonstration with single-trial auditory-evoked responses
    Samu Taulu
    Elekta Neuromag Oy, Helsinki, Finland
    Hum Brain Mapp 30:1524-34. 2009
    ..by normal environmental interference, by artificially produced additional external interference, and by nearby artifacts produced by a piece of magnetized wire in the subject's lip...
  64. ncbi Removal of FMRI environment artifacts from EEG data using optimal basis sets
    R K Niazy
    University of Oxford, Centre for Functional MRI of the Brain FMRIB, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Neuroimage 28:720-37. 2005
    ..However, EEG data collected in such experiments suffer from two kinds of artifact. First, gradient artifacts are caused by the switching of magnetic gradients during FMRI...
  65. ncbi Physiological noise effects on the flip angle selection in BOLD fMRI
    J Gonzalez-Castillo
    Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Neuroimage 54:2764-78. 2011
    ..of RF power, (2) limitation of apparent T(1)-related inflow effects, (3) reduction of through-plane motion artifacts, (4) lower levels of physiological noise, and (5) improved tissue contrast is feasible when physiological noise ..
  66. ncbi Thresholding of statistical maps in functional neuroimaging using the false discovery rate
    Christopher R Genovese
    Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Neuroimage 15:870-8. 2002
    ..We demonstrate this approach using both simulations and functional magnetic resonance imaging data from two simple experiments...
  67. ncbi A multistage knowledge-based system for EEG seizure detection in newborn infants
    Ardalan Aarabi
    GRAMFC, EFSN Péd, CHU Nord, Place V Pauchet, 80054, Amiens, France
    Clin Neurophysiol 118:2781-97. 2007
    ..neonates because they lack information about specific age-dependent features of normal and pathological EEG and artifacts. This paper describes a novel multistage knowledge-based seizure detection system for newborn infants to ..
  68. ncbi Removal of muscle artifacts from EEG recordings of spoken language production
    Maarten De Vos
    Department of Electrical Engineering ESAT, Katholieke Universiteit Leuven, Leuven, Belgium
    Neuroinformatics 8:135-50. 2010
    ..processing has often avoided investigating spoken language production by fear of the electromyographic (EMG) artifacts that articulation induces on the electro-encephalogram (EEG) signal...
  69. ncbi Properties of the ballistocardiogram artefact as revealed by EEG recordings at 1.5, 3 and 7 T static magnetic field strength
    Stefan Debener
    Medical Research Council Institute of Hearing Research, Royal South Hants Hospital, Southampton, SO14 OYG, United Kingdom
    Int J Psychophysiol 67:189-99. 2008
    ..This is summarized in a preliminary BCG model that may help to explain recent inconsistencies regarding the usefulness of ICA for BCG removal. It may also guide the future development of more advanced BCG removal procedures...
  70. ncbi Independent component analysis using an extended infomax algorithm for mixed subgaussian and supergaussian sources
    T W Lee
    Computational Neurobiology Lab, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92038, USA
    Neural Comput 11:417-41. 1999
    ..Applied to high-dimensional data from electroencephalographic recordings, it is effective at separating artifacts such as eye blinks and line noise from weaker electrical signals that arise from sources in the brain.
  71. ncbi An experimental correction for arginine-to-proline conversion artifacts in SILAC-based quantitative proteomics
    Dennis Van Hoof
    Nat Methods 4:677-8. 2007
  72. ncbi Beam hardening artifacts in micro-computed tomography scanning can be reduced by X-ray beam filtration and the resulting images can be used to accurately measure BMD
    Jeffrey A Meganck
    Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA
    Bone 45:1104-16. 2009
    ..However, the ability to measure the BMD directly from microCT images can be biased by artifacts, such as beam hardening, in the image...
  73. ncbi A model-based objective evaluation of eye movement correction in EEG recordings
    Joep J M Kierkels
    Electrical Engineering Department, Eindhoven University of Technology, The Netherlands
    IEEE Trans Biomed Eng 53:246-53. 2006
    We present a method to quantitatively and objectively compare algorithms for correction of eye movement artifacts in a simulated ongoing electroencephalographic signal (EEG)...
  74. ncbi An evaluation of automated neonatal seizure detection methods
    Stephen Faul
    Department of Electrical and Electronic Engineering, University College Cork, College Road, Cork, Ireland
    Clin Neurophysiol 116:1533-41. 2005
    ..To evaluate 3 published automated algorithms for detecting seizures in neonatal EEG...
  75. ncbi Magnetic resonance imaging of freely moving objects: prospective real-time motion correction using an external optical motion tracking system
    M Zaitsev
    Medical Physics, Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetterstr 55, 79106 Freiburg, Germany
    Neuroimage 31:1038-50. 2006
    ..The high performance and image quality improvement in case of subject motion are demonstrated for various imaging techniques such as gradient and spin echo, as well as echo planar imaging...
  76. ncbi FRET or no FRET: a quantitative comparison
    Claude Berney
    BioMicroMetrics Group, Laboratory for Biomechanics, Swiss Federal Institute of Technology, CH 8952 Schlieren, Switzerland
    Biophys J 84:3992-4010. 2003
    ..Finally, we test their sensitivity and draw conclusions for the preparation of FRET experiments in more complex and less-controlled systems...
  77. ncbi Sources of functional magnetic resonance imaging signal fluctuations in the human brain at rest: a 7 T study
    Marta Bianciardi
    Advanced MRI Section, LFMI, NINDS, National Institutes of Health, Bethesda, MD 20892 1065, USA
    Magn Reson Imaging 27:1019-29. 2009
    ..Under the conditions of this study, spontaneous neuronal activity is one of the major contributors to the measured fMRI signal fluctuations, increasing almost twofold relative to earlier experiments under similar conditions at 3 T...
  78. ncbi Non-white noise in fMRI: does modelling have an impact?
    Torben E Lund
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Kettegaard Alle 30, 2650 Hvidovre, Denmark
    Neuroimage 29:54-66. 2006
    ..In addition, we also compare the performance of the NVR method to the whitening approach implemented in SPM2...
  79. ncbi MRI artifacts in human brain tissue after prolonged formalin storage
    Sara van Duijn
    Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
    Magn Reson Med 65:1750-8. 2011
    ..These findings show that prolonged storaged of formalin fixed brain tissue results in subtle histology artifacts, which show on MRI as hypointensities that on first appearance are indistinguishable from genuine brain ..
  80. ncbi Projecting out muscle artifacts from TMS-evoked EEG
    Hanna Mäki
    Department of Biomedical Engineering and Computational Science BECS, Aalto University, Aalto, Espoo, Finland
    Neuroimage 54:2706-10. 2011
    ..The presented artifact removal method enables one to study the cortical state when stimulating areas near the cranial muscles...
  81. ncbi EEG windowed statistical wavelet scoring for evaluation and discrimination of muscular artifacts
    Francois Benoit Vialatte
    Lab ABSP, RIKEN Brain Science Institute, Wako Shi, Japan
    Physiol Meas 29:1435-52. 2008
    EEG recordings are usually corrupted by spurious extra-cerebral artifacts, which should be rejected or cleaned up by the practitioner...
  82. ncbi Accelerometer-based method for correcting signal baseline changes caused by motion artifacts in medical near-infrared spectroscopy
    Jaakko Virtanen
    Aalto University School of Science, Department of Biomedical Engineering and Computational Science, P O Box 12200, FI 00076 Aalto, Finland
    J Biomed Opt 16:087005. 2011
    ..We present an accelerometer-based motion artifact removal (ABAMAR) algorithm for correcting such baseline motion artifacts (BMAs). ABAMAR can be easily adapted to various long-term monitoring applications of NIRS...
  83. ncbi Assessing and improving the spatial accuracy in MEG source localization by depth-weighted minimum-norm estimates
    Fa Hsuan Lin
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Building 149 13th St Charlestown, MA 02129, USA
    Neuroimage 31:160-71. 2006
    ..The application of depth weighting to auditory and somatosensory experimental data illustrated the beneficial effect of depth weighting on the accuracy of spatiotemporal mapping of neuronal sources...
  84. ncbi Reduction of dental filling metallic artifacts in CT-based attenuation correction of PET data using weighted virtual sinograms optimized by a genetic algorithm
    Mehrsima Abdoli
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands
    Med Phys 37:6166-77. 2010
    ..of metallic dental fillings is prevalent in head and neck PET/CT imaging and generates bright and dark streaking artifacts in reconstructed CT images...
  85. ncbi Analysis of titanium induced CT artifacts in the development of biomechanical finite element models
    C Zannoni
    Department of Electronics, Computer Science and Systems, University of Bologna, Italy
    Med Eng Phys 20:653-9. 1998
    ..Metallic implants, however, generate artifacts, typically seen as starburst streaking...
  86. ncbi Statistical artifacts in diffusion tensor MRI (DT-MRI) caused by background noise
    P J Basser
    Section on Tissue Biophysics and Biomimetics, Laboratory of Integrative and Medical Biophysics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, 20892 5772, USA
    Magn Reson Med 44:41-50. 2000
    This work helps elucidate how background noise introduces statistical artifacts in the distribution of the sorted eigenvalues and eigenvectors in diffusion tensor MRI (DT-MRI) data...
  87. ncbi Using pulse oximetry to account for high and low frequency physiological artifacts in the BOLD signal
    Timothy D Verstynen
    Keck Center for Integrative Neuroscience, University of California, San Francisco, San Francisco, CA, USA
    Neuroimage 55:1633-44. 2011
    ..the different frequency components of the PO signal could be used to identify different types of physiological artifacts in the BOLD response...
  88. ncbi Comparison of ring artifact correction methods for flat-detector CT
    Daniel Prell
    Institute of Medical Physics, University of Erlangen Nurnberg, Henkestrasse 91, 91052 Erlangen, Germany
    Phys Med Biol 54:3881-95. 2009
    In flat-detector CT, imperfect or defect detector elements may cause concentric ring artifacts due to their continuous over- or underestimation of attenuation values, which often disturb image quality...
  89. ncbi Beamformer suppression of cochlear implant artifacts in an electroencephalography dataset
    Daniel D E Wong
    Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON M5S3G9, Canada
    IEEE Trans Biomed Eng 56:2851-7. 2009
    ..The effectiveness of the method is then demonstrated using simulated data and electroencephalography data from a CI user...
  90. ncbi Common orthodontic appliances cause artifacts that degrade the diagnostic quality of CBCT images
    Matthew A Sanders
    Jerry L Pettis Memorial VA Medical Center, Loma Linda, CA, USA
    J Calif Dent Assoc 35:850-7. 2007
    This study evaluates artifacts generated by orthodontic brackets in CBCT images.
  91. ncbi In vivo evaluation of the carotid wallstent on three-dimensional contrast material-enhanced MR angiography: influence of artifacts on the visibility of stent lumina
    Ingitha Borisch
    Department of Diagnostic Radiology, University Hospital Regensburg, Germany
    J Vasc Interv Radiol 16:669-77. 2005
    ..The main limitations are stent-related artifacts compromising the visibility of the stent lumen...
  92. ncbi Ring artifact correction for high-resolution micro CT
    Yiannis Kyriakou
    Institute of Medical Physics, University of Erlangen Nurnberg, Germany
    Phys Med Biol 54:N385-91. 2009
    ..micro CT using flat detectors (FD), imperfect or defect detector elements may cause concentric-ring artifacts due to their continuous over- or underestimation of attenuation values, which often disturb image quality...
  93. ncbi Metal artifact reduction from reformatted projections for hip prostheses in multislice helical computed tomography: techniques and initial clinical results
    Lifeng Yu
    Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Invest Radiol 44:691-6. 2009
    Hip prosthesis is one of the most common types of metal implants and can cause significant artifacts in computed tomography (CT) examinations...
  94. ncbi Three-dimensional rotational angiography of transplanted renal arteries: influence of an extended angle of rotation on beam-hardening artifacts
    G Hagen
    Department of Oncology, Radiology and Clinical Immunology, Section of Radiology, Akademiska sjukhuset, Uppsala, Sweden
    Acta Radiol 46:170-6. 2005
    ..3D-RA) of the transplant renal artery performed with an extended angle of rotation can reduce beam-hardening artifacts in 3D reconstructed images without image quality being lost or side effects to the transplanted kidney being ..
  95. ncbi Two-stage approach for detection and reduction of motion artifacts in photoplethysmographic data
    Rajet Krishnan
    Department of Electrical and Computer Engineering, Kansas State University, Manhattan, KS 66506, USA
    IEEE Trans Biomed Eng 57:1867-76. 2010
    Corruption of photopleythysmograms (PPGs) by motion artifacts has been a serious obstacle to the reliable use of pulse oximeters for real-time, continuous state-of-health monitoring...
  96. ncbi Respiratory-gated CT as a tool for the simulation of breathing artifacts in PET and PET/CT
    J J Hamill
    Siemens Medical Solutions, Knoxville, Tennessee 37932, USA
    Med Phys 35:576-85. 2008
    ..The problem of missed tumors near the diaphragm can be reduced by acquiring attenuation-correction information near end expiration. A simple PET/CT protocol requiring no gating equipment also addresses this problem...
  97. ncbi Artifact correction and source analysis of early electroencephalographic responses evoked by transcranial magnetic stimulation over primary motor cortex
    Vladimir Litvak
    Faculty of Biomedical Engineering, Technion Israel Institute of Technology, Haifa, Israel
    Neuroimage 37:56-70. 2007
    ..the EEG responses during the several tens of milliseconds immediately following the stimulus due to TMS-induced artifacts. In the present study we show that by combining a specially adapted recording system with software artifact ..
  98. ncbi Classification of ring artifacts for their effective removal using type adaptive correction schemes
    Emran Mohammad Abu Anas
    Department of Electrical and Electronic Engineering, Bangladesh University of Engineering and Technology, Dhaka 1000, Bangladesh
    Comput Biol Med 41:390-401. 2011
    ..High resolution tomographic images acquired with a digital X-ray detector are often degraded by the so called ring artifacts. In this paper, a detail analysis including the classification, detection and correction of these ring artifacts ..
  99. ncbi Field inhomogeneity correction based on gridding reconstruction for magnetic resonance imaging
    Holger Eggers
    Philips Research Europe, Sector Medical Imaging Systems, 22335 Hamburg, Germany
    IEEE Trans Med Imaging 26:374-84. 2007
    Spatial variations of the main field give rise to artifacts in magnetic resonance images if disregarded in reconstruction. With non-Cartesian k-space sampling, they often lead to unacceptable blurring...
  100. ncbi Characterization, prediction, and correction of geometric distortion in 3 T MR images
    Lesley N Baldwin
    Division of Medical Physics, Department of Physics, University of Alberta, Canada
    Med Phys 34:388-99. 2007
    ..5 T. Finally, the image slices were corrected for distortion in order to provide geometrically accurate phantom images...
  101. ncbi A maximum likelihood approach to parallel imaging with coil sensitivity noise
    Ashish Raj
    Radiology Department, Weill Medical College of Cornell University, Ithaca, NY 14853, USA
    IEEE Trans Med Imaging 26:1046-57. 2007
    ....

Research Grants87

  1. Offset Astigmatic and Variable Focusing Collimation for Helical SPECT Brain Scans
    RONALD JASZCZAK; Fiscal Year: 2006
    ..when applied to brain imaging: i) The source distribution is not completely sampled, which results in image artifacts for axial source locations that are not near the collimator's central, transaxial (perpendicular) focal plane; ..
  2. Harmonically detected swept source OCT
    Kristen Peterson; Fiscal Year: 2007
    ..optical coherence tomography by achieving noise-limited removal of the complex conjugate ambiguity and other artifacts. Our approach provides better artifact rejection ratios with simpler instrumentation than other methods...
  3. Time Resolved Cardiac Computed Tomography with Patient Dose Reduction
    Katsuyuki Taguchi; Fiscal Year: 2009
    ..Then, images are reconstructed by neglecting the cardiac motion within the time window resulting in blurring and artifacts in the reconstructed images...
  4. Near Term Development of Reagents and Enzymes for Genome Sequencing
    Steven A Benner; Fiscal Year: 2010
    ..multiplexed priming and PCR with primers having an effective length of 16mers (or longer) without creating PCR artifacts and supporting single nucleotide discrimination, (b) AEGIS tags appended to SAMRS primers that allow binning of ..
  5. True Direct Single Molecule RNA Sequencing
    PATRICE MARIE MILOS; Fiscal Year: 2010
    ..This step has been shown to introduce many biases and artifacts. In order to best characterize the "true" transcriptome, we propose the application of single molecule, true ..
  6. Deep Brain Stimulation in the Parkinsonian Monkey
    JERROLD VITEK; Fiscal Year: 2009
    ..of DBS only after stimulation has been discontinued due to the problems associated with electrical stimulation artifacts. The results from many of these studies have been contradictory, likely secondary to the variety of conditions ..
  7. Deep Brain Stimulation in the Parkinsonian Monkey
    Jerrold L Vitek; Fiscal Year: 2010
    ..of DBS only after stimulation has been discontinued due to the problems associated with electrical stimulation artifacts. The results from many of these studies have been contradictory, likely secondary to the variety of conditions ..
  8. Functional brain imaging by laser-induced PAT
    Lihong Wang; Fiscal Year: 2006
    ..the proposed technology, functional photoacoustic tomography (fPAT), can image the intact brain free of speckle artifacts. Besides structural information, the proposed fPAT can also provide functional information including blood ..
  9. Functional brain imaging by laser-induced PAT
    Lihong Wang; Fiscal Year: 2007
    ..the proposed technology, functional photoacoustic tomography (fPAT), can image the intact brain free of speckle artifacts. Besides structural information, the proposed fPAT can also provide functional information including blood ..
  10. An Advanced Technology Flat-Panel Imager for Fluoroscopy
    Larry E Antonuk; Fiscal Year: 2010
    ..Secondly, AMFPIs are subject to image artifacts, originating from the trapping of charge in amorphous materials in the arrays...
  11. The Endothelial Glycocalyx: Its Structure and Function and as a Mechanotransducer
    John M Tarbell; Fiscal Year: 2010
    ..Because of dehydration artifacts associated with conventional electron microscopy, even such rudimentary characteristics as the thickness of the ..
  12. PATIENT MOTION DETECTION AND COMPENSATION IN SPECT
    Michael A King; Fiscal Year: 2010
    Patient motion is an ever-present potential cause of artifacts that can limit the accuracy of diagnostic imaging...
  13. Real-Time MRI Motion Correction System
    Roland Bammer; Fiscal Year: 2010
    MOTIVATION - Motion remains one of the most frequent contributors to image artifacts in MR studies. The motion susceptibility of MRI is well-known and has spawned a number of elegant navigation techniques...
  14. Respiratory Motion-Reduced Cone-Beam CT Guidance of Radiotherapy in Lung & Liver
    Gikas Mageras; Fiscal Year: 2009
    ..We propose to develop and evaluate methods to reduce respiratory-induced motion artifacts in CBCT...
  15. Ultrasound Imaging of Breast by Use of a Hemispheric Array and Inverse Scattering
    Robert C Waag; Fiscal Year: 2010
    ..g., about two seconds, to avoid image-degrading motion artifacts. The planned use of off-line processing by available computing resources for image reconstruction circumvents ..
  16. HIGH RESOLUTION MR ANGIOGRAPHY
    Dennis Parker; Fiscal Year: 2002
    ..RF imaging coils with the goal to further improve vascular detail, increase spatial resolution and decrease clip artifacts. First, we will evaluate sliding interleaved projection reconstruction (SLIPR) and a novel improvement to ..
  17. Novel Ether Containing Ligand Complexes: Cardiac Imaging
    KEVIN MARESCA; Fiscal Year: 2004
    ..and ischemia, the energy spectrum of thallium- 201 makes it particularly prone to soft tissue attenuation artifacts. While there are two FDA-approved Tc-99m perfusion tracers, having more favorable energy spectra for imaging, ..
  18. ADDRESSING THE ISSUE OF GAP REGIONS IN GENOME SEQUENCING
    John SantaLucia; Fiscal Year: 2001
    ..Gap regions occur because of a variety of sequencing artifacts including mispriming of directed oligonucleotide primers, band-compressions in gel electrophoresis, and the ..
  19. HIGH RESOLUTION CONTRAST ENHANCED MR ANGIOGRAPHY
    Charles Mistretta; Fiscal Year: 2001
    ..Sparse sampling in X-ray computed tomography (CT) using filtered back projection (FBP) produces "clutter" artifacts which are large relative to the small differences in tissue attenuation displayed by CT...
  20. ENHANCED NAVIGATOR SPIRAL CORONARY MR ANGIOGRAPHY
    Yi Wang; Fiscal Year: 2003
    ..Aim 4. Implement and test contrast enhanced navigator spiral CMRA in an animal model. Imaging artifacts from cardiac and respiratory motion continue to be the major challenge for CMRA...
  21. Offset Astigmatic and Variable Focusing Collimation for Helical SPECT Brain Scans
    RONALD JASZCZAK; Fiscal Year: 2007
    ..when applied to brain imaging: i) The source distribution is not completely sampled, which results in image artifacts for axial source locations that are not near the collimator's central, transaxial (perpendicular) focal plane; ..
  22. Near Term Development of Reagents and Enzymes for Genome Sequencing
    Steven Benner; Fiscal Year: 2009
    ..multiplexed priming and PCR with primers having an effective length of 16mers (or longer) without creating PCR artifacts and supporting single nucleotide discrimination, (b) AEGIS tags appended to SAMRS primers that allow binning of ..
  23. Near Term Development of Reagents and Enzymes for Genome Sequencing
    Steven Benner; Fiscal Year: 2009
    ..multiplexed priming and PCR with primers having an effective length of 16mers (or longer) without creating PCR artifacts and supporting single nucleotide discrimination, (b) AEGIS tags appended to SAMRS primers that allow binning of ..
  24. Electron Tomography of the Outer Hair Cell Lateral Wall
    WILLIAM TRIFFO; Fiscal Year: 2007
    ..wall structure has been limited to extrapolation from 2D studies of samples, further complicated by preservation artifacts depending on the sample preparation method used...
  25. Real-Time MRI Motion Correction System
    Roland Bammer; Fiscal Year: 2007
    MOTIVATION - Motion remains one of the most frequent contributors to image artifacts in MR studies. The motion susceptibility of MRI is well-known and has spawned a number of elegant navigation techniques...
  26. Promiscuous and Specific Inhibitors of Cruzain
    Brian Shoichet; Fiscal Year: 2007
    ..Multiple mechanisms have been proposed to explain these artifacts, including chemical reactivity, oxidation, assay interference, and colloidal aggregation...
  27. Respiratory Motion-Reduced Cone-Beam CT Guidance of Radiotherapy in Lung & Liver
    Gikas S Mageras; Fiscal Year: 2010
    ..We propose to develop and evaluate methods to reduce respiratory-induced motion artifacts in CBCT...
  28. Respiratory Motion-Reduced Cone-Beam CT Guidance of Radiotherapy in Lung & Liver
    Gikas Mageras; Fiscal Year: 2009
    ..We propose to develop and evaluate methods to reduce respiratory-induced motion artifacts in CBCT...