body mass index

Summary

Summary: An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)

Top Publications

  1. pmc Establishing a standard definition for child overweight and obesity worldwide: international survey
    T J Cole
    Department of Epidemiology and Public Health, Institute of Child Health, London WC1N 1EH
    BMJ 320:1240-3. 2000
  2. ncbi Prevalence and trends in obesity among US adults, 1999-2008
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Rd, Room 4315, Hyattsville, MD 20782, USA
    JAMA 303:235-41. 2010
  3. pmc Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
    Elizabeth K Speliotes
    Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA
    Nat Genet 42:937-48. 2010
  4. doi Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Rd, Room 4315, Hyattsville, MD 20782, USA
    JAMA 307:491-7. 2012
  5. doi National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants
    Mariel M Finucane
    Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA
    Lancet 377:557-67. 2011
  6. doi Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010
    Cynthia L Ogden
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland 20782, USA
    JAMA 307:483-90. 2012
  7. ncbi Prevalence of high body mass index in US children and adolescents, 2007-2008
    Cynthia L Ogden
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    JAMA 303:242-9. 2010
  8. pmc Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    William C Knowler
    Diabetes Prevention Program Coordinating Center, Biostatistics Center, George Washington University, 6110 Executive Blvd, Suite 750, Rockville, MD 20852, USA
    N Engl J Med 346:393-403. 2002
  9. ncbi Prediction of coronary heart disease using risk factor categories
    P W Wilson
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Mass 01701, USA
    Circulation 97:1837-47. 1998
  10. pmc Development of a WHO growth reference for school-aged children and adolescents
    Mercedes de Onis
    Department of Nutrition, World Health Organization, Geneva, Switzerland
    Bull World Health Organ 85:660-7. 2007

Detail Information

Publications232 found, 100 shown here

  1. pmc Establishing a standard definition for child overweight and obesity worldwide: international survey
    T J Cole
    Department of Epidemiology and Public Health, Institute of Child Health, London WC1N 1EH
    BMJ 320:1240-3. 2000
    ..To develop an internationally acceptable definition of child overweight and obesity, specifying the measurement, the reference population, and the age and sex specific cut off points...
  2. ncbi Prevalence and trends in obesity among US adults, 1999-2008
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Rd, Room 4315, Hyattsville, MD 20782, USA
    JAMA 303:235-41. 2010
    ..The prevalence of obesity increased in the United States between 1976-1980 and 1988-1994 and again between 1988-1994 and 1999-2000...
  3. pmc Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
    Elizabeth K Speliotes
    Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA
    Nat Genet 42:937-48. 2010
    ..To identify genetic loci for obesity susceptibility, we examined associations between body mass index and ∼ 2...
  4. doi Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Rd, Room 4315, Hyattsville, MD 20782, USA
    JAMA 307:491-7. 2012
    Between 1980 and 1999, the prevalence of adult obesity (body mass index [BMI] ≥30) increased in the United States and the distribution of BMI changed. More recent data suggested a slowing or leveling off of these trends.
  5. doi National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants
    Mariel M Finucane
    Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA
    Lancet 377:557-67. 2011
    ..However, few worldwide comparative analyses of long-term trends of body-mass index (BMI) have been done, and none have used recent national health examination surveys. We estimated worldwide trends in population mean BMI...
  6. doi Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010
    Cynthia L Ogden
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland 20782, USA
    JAMA 307:483-90. 2012
    ..The prevalence of childhood obesity increased in the 1980s and 1990s but there were no significant changes in prevalence between 1999-2000 and 2007-2008 in the United States...
  7. ncbi Prevalence of high body mass index in US children and adolescents, 2007-2008
    Cynthia L Ogden
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    JAMA 303:242-9. 2010
    The prevalence of high body mass index (BMI) among children and adolescents in the United States appeared to plateau between 1999 and 2006.
  8. pmc Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    William C Knowler
    Diabetes Prevention Program Coordinating Center, Biostatistics Center, George Washington University, 6110 Executive Blvd, Suite 750, Rockville, MD 20852, USA
    N Engl J Med 346:393-403. 2002
    ..We hypothesized that modifying these factors with a lifestyle-intervention program or the administration of metformin would prevent or delay the development of diabetes...
  9. ncbi Prediction of coronary heart disease using risk factor categories
    P W Wilson
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Mass 01701, USA
    Circulation 97:1837-47. 1998
    ....
  10. pmc Development of a WHO growth reference for school-aged children and adolescents
    Mercedes de Onis
    Department of Nutrition, World Health Organization, Geneva, Switzerland
    Bull World Health Organ 85:660-7. 2007
    To construct growth curves for school-aged children and adolescents that accord with the WHO Child Growth Standards for preschool children and the body mass index (BMI) cut-offs for adults.
  11. ncbi Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
    Eugenia E Calle
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta 30329, USA
    N Engl J Med 348:1625-38. 2003
    ..The influence of excess body weight on the risk of death from cancer has not been fully characterized...
  12. pmc Body-mass index and mortality among 1.46 million white adults
    Amy Berrington de Gonzalez
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    N Engl J Med 363:2211-9. 2010
    ....
  13. pmc Genome-wide association analysis of metabolic traits in a birth cohort from a founder population
    Chiara Sabatti
    Department of Human Genetics and Los Angeles, Los Angeles, California 90095, USA
    Nat Genet 41:35-46. 2009
    ..triglycerides, high-density lipoprotein, low-density lipoprotein, glucose, insulin, C-reactive protein, body mass index, and systolic and diastolic blood pressure) in the Northern Finland Birth Cohort 1966 (NFBC1966), drawn from ..
  14. ncbi Evidence based physical activity for school-age youth
    William B Strong
    Department of Pediatrics, Medical College of Georgia, Augusta, Georgia, USA
    J Pediatr 146:732-7. 2005
    ..To review the effects of physical activity on health and behavior outcomes and develop evidence-based recommendations for physical activity in youth...
  15. pmc A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    Timothy M Frayling
    Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, Magdalen Road, Exeter, UK
    Science 316:889-94. 2007
    ..variant in the FTO (fat mass and obesity associated) gene that predisposes to diabetes through an effect on body mass index (BMI). An additive association of the variant with BMI was replicated in 13 cohorts with 38,759 participants...
  16. ncbi Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
    Ali H Mokdad
    Division of Adult and Community Health, 4770 National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341 3717, USA
    JAMA 289:76-9. 2003
    ..Obesity and diabetes are increasing in the United States...
  17. ncbi Effects of bariatric surgery on mortality in Swedish obese subjects
    Lars Sjöström
    Institute of Medicine, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden
    N Engl J Med 357:741-52. 2007
    ..In fact, many observational studies suggest that weight reduction is associated with increased mortality...
  18. ncbi The obesity epidemic in the United States--gender, age, socioeconomic, racial/ethnic, and geographic characteristics: a systematic review and meta-regression analysis
    Youfa Wang
    Center for Human Nutrition, Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Epidemiol Rev 29:6-28. 2007
    ..Adult overweight and obesity were defined by using body mass index (weight (kg)/height (m)(2)) cutpoints of 25 and 30, respectively; childhood "at risk for overweight" and ..
  19. ncbi Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study
    Salim Yusuf
    Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Canada
    Lancet 366:1640-9. 2005
    ..We aimed to assess whether markers of obesity, especially waist-to-hip ratio, would be stronger indicators of myocardial infarction than body-mass index (BMI), the conventional measure...
  20. ncbi Obesity in children and young people: a crisis in public health
    T Lobstein
    IASO International Obesity TaskForce, 231 North Gower Street, London NW1 2NS, UK
    Obes Rev 5:4-104. 2004
  21. doi Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
    Andrew G Renehan
    Department of Surgery, School of Cancer Studies, University of Manchester, UK
    Lancet 371:569-78. 2008
    ..We did a systematic review and meta-analysis to assess the strength of associations between BMI and different sites of cancer and to investigate differences in these associations between sex and ethnic groups...
  22. doi General and abdominal adiposity and risk of death in Europe
    T Pischon
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbruecke, Germany
    N Engl J Med 359:2105-20. 2008
    ....
  23. pmc Childhood body-mass index and the risk of coronary heart disease in adulthood
    Jennifer L Baker
    Institute of Preventive Medicine, Center for Health and Society, Copenhagen, Denmark
    N Engl J Med 357:2329-37. 2007
    ..Risk factors for coronary heart disease (CHD) are already identifiable in overweight children. The severity of the long-term effects of excess childhood weight on CHD, however, remains unknown...
  24. pmc Body mass index cut offs to define thinness in children and adolescents: international survey
    Tim J Cole
    Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, London WC1N 1EH
    BMJ 335:194. 2007
    To determine cut offs to define thinness in children and adolescents, based on body mass index at age 18 years.
  25. ncbi Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery
    Lars Sjöström
    Department of Body Composition and Metabolism, Sahlgrenska University Hospital, Goteborg, Sweden
    N Engl J Med 351:2683-93. 2004
    ..Weight loss is associated with short-term amelioration and prevention of metabolic and cardiovascular risk, but whether these benefits persist over time is unknown...
  26. ncbi Exercise capacity and mortality among men referred for exercise testing
    Jonathan Myers
    Division of Cardiovascular Medicine, Stanford University Medical Center and the Veterans Affairs Palo Alto Health Care System, Palo Alto, Calif CA 94304, USA
    N Engl J Med 346:793-801. 2002
    ..There is also uncertainty regarding the predictive power of exercise capacity relative to other clinical and exercise-test variables...
  27. doi Genetics of gene expression and its effect on disease
    Valur Emilsson
    deCODE Genetics, 101 Reykjavik, Iceland
    Nature 452:423-8. 2008
    ..A core network module in humans and mice was identified that is enriched for genes involved in the inflammatory and immune response and has been found to be causally associated to obesity-related traits...
  28. ncbi Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women
    Frank B Hu
    Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
    JAMA 289:1785-91. 2003
    ..Current public health campaigns to reduce obesity and type 2 diabetes have largely focused on increasing exercise, but have paid little attention to the reduction of sedentary behaviors...
  29. ncbi A comparison of direct vs. self-report measures for assessing height, weight and body mass index: a systematic review
    S Connor Gorber
    Physical Health Measures Division, Statistics Canada, Ottawa, ON, Canada
    Obes Rev 8:307-26. 2007
    ..the agreement between objective (measured) and subjective (reported) measures in assessing height, weight and body mass index (BMI)...
  30. ncbi Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994
    Stephen Cook
    Strong Children s Research Center, Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Arch Pediatr Adolesc Med 157:821-7. 2003
    ..In adults the metabolic syndrome imposes a substantial risk for type 2 diabetes mellitus and premature coronary heart disease. Even so, no national estimate is currently available of the prevalence of this syndrome in adolescents...
  31. pmc Meta-analysis identifies common variants associated with body mass index in east Asians
    Wanqing Wen
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Nat Genet 44:307-11. 2012
    Multiple genetic loci associated with obesity or body mass index (BMI) have been identified through genome-wide association studies conducted predominantly in populations of European ancestry...
  32. doi Obesity and the metabolic syndrome in developing countries
    Anoop Misra
    Department of Diabetes and Metabolic Diseases, Fortis Flt Lt Rajan Dhall Hospital, Vasant Kunj, New Delhi 110070, India
    J Clin Endocrinol Metab 93:S9-30. 2008
    ..Prevalence of obesity and the metabolic syndrome is rapidly increasing in developing countries, leading to increased morbidity and mortality due to type 2 diabetes mellitus (T2DM) and cardiovascular disease...
  33. pmc Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
    Cristen J Willer
    Genetic Investigation of ANthropometric Traits Consortium
    Nat Genet 41:25-34. 2009
    Common variants at only two loci, FTO and MC4R, have been reproducibly associated with body mass index (BMI) in humans...
  34. pmc The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994
    Yong Woo Park
    Department of Family Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea
    Arch Intern Med 163:427-36. 2003
    ..The extent to which the metabolic syndrome is associated with demographic and potentially modifiable lifestyle factors in the US population is unknown...
  35. ncbi Elevated C-reactive protein levels in overweight and obese adults
    M Visser
    Institute for Research in Extramural Medicine, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands
    JAMA 282:2131-5. 1999
    ..Human adipose tissue expresses and releases the proinflammatory cytokine interleukin 6, potentially inducing low-grade systemic inflammation in persons with excess body fat...
  36. pmc Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
    Richa Saxena
    Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Nat Genet 42:142-8. 2010
    ..Of the three newly implicated loci (GIPR, ADCY5 and VPS13C), only ADCY5 was found to be associated with type 2 diabetes in collaborating studies (n = 35,869 cases, 89,798 controls, OR = 1.12, 95% CI 1.09-1.15, P = 4.8 x 10(-18))...
  37. pmc Childhood obesity, other cardiovascular risk factors, and premature death
    Paul W Franks
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA
    N Engl J Med 362:485-93. 2010
    ..The effect of childhood risk factors for cardiovascular disease on adult mortality is poorly understood...
  38. ncbi The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US population (NHANES 1999-2004)
    Rachel P Wildman
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Belfer Building, Room 1309, Bronx, NY 10461, USA
    Arch Intern Med 168:1617-24. 2008
    ....
  39. pmc Body mass index, waist circumference and waist-hip ratio: which is the better discriminator of cardiovascular disease mortality risk?: evidence from an individual-participant meta-analysis of 82 864 participants from nine cohort studies
    S Czernichow
    Centre for research in Epidemiology and Population Health, Hopital Paul Brousse, Villejuif, France
    Obes Rev 12:680-7. 2011
    ..b>Body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) were measured directly...
  40. pmc Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
    Tuomas O Kilpeläinen
    Medical Research Council MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Nat Genet 43:753-60. 2011
    Genome-wide association studies have identified 32 loci influencing body mass index, but this measure does not distinguish lean from fat mass. To identify adiposity loci, we meta-analyzed associations between ∼2...
  41. pmc The relationship of waist circumference and BMI to visceral, subcutaneous, and total body fat: sex and race differences
    Sarah M Camhi
    Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
    Obesity (Silver Spring) 19:402-8. 2011
    ..Sex differences, and in some instances race differences, in the relationships between anthropometry and fat-specific depots demonstrate that these characteristics need to be considered when predicting adiposity from WC or BMI...
  42. pmc Association between body-mass index and risk of death in more than 1 million Asians
    Wei Zheng
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA
    N Engl J Med 364:719-29. 2011
    ..Most studies that have evaluated the association between the body-mass index (BMI) and the risks of death from any cause and from specific causes have been conducted in populations of European origin...
  43. doi A systematic review of waist-to-height ratio as a screening tool for the prediction of cardiovascular disease and diabetes: 0·5 could be a suitable global boundary value
    Lucy M Browning
    Ashwell Associates Ltd, Ashwell Street, Ashwell, Hertfordshire SG7 5PZ, UK
    Nutr Res Rev 23:247-69. 2010
    ....
  44. ncbi The epidemiology of obesity
    Cynthia L Ogden
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland 20782, USA
    Gastroenterology 132:2087-102. 2007
    ..Among adults, obesity is defined as a body mass index of 30 or greater...
  45. ncbi Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men
    Youfa Wang
    Department of Human Nutrition and Division of Epidemiology and Biostatistics, University of Illinois at Chicago, USA
    Am J Clin Nutr 81:555-63. 2005
    ..However, few studies have compared the predictive power of overall obesity with that of central obesity. The cutoffs for waist circumference (WC) and waist-to-hip ratio (WHR) as measures of abdominal adiposity remain controversial...
  46. ncbi Cause-specific excess deaths associated with underweight, overweight, and obesity
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    JAMA 298:2028-37. 2007
    The association of body mass index (BMI) with cause-specific mortality has not been reported for the US population.
  47. ncbi Waist circumference and not body mass index explains obesity-related health risk
    Ian Janssen
    Department of Community Health and Epidemiology, Queen s University, Kingston, Canada
    Am J Clin Nutr 79:379-84. 2004
    The addition of waist circumference (WC) to body mass index (BMI; in kg/m(2)) predicts a greater variance in health risk than does BMI alone; however, whether the reverse is true is not known.
  48. pmc Association between general and central adiposity in childhood, and change in these, with cardiovascular risk factors in adolescence: prospective cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol BS8 2BN, UK
    BMJ 341:c6224. 2010
    To examine the prospective associations between body mass index (BMI), waist circumference, and fat mass in childhood and cardiovascular risk factors at age 15-16.
  49. pmc Life course variations in the associations between FTO and MC4R gene variants and body size
    Rebecca Hardy
    MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College London, 33 Bedford Place, London, UK
    Hum Mol Genet 19:545-52. 2010
    The timing of associations between common genetic variants for weight or body mass index (BMI) across the life course may provide insights into the aetiology of obesity...
  50. pmc A multicenter, randomized trial of treatment for mild gestational diabetes
    Mark B Landon
    Department of Obstetrics and Gynecology, Ohio State University, Columbus, USA
    N Engl J Med 361:1339-48. 2009
    ..It is uncertain whether treatment of mild gestational diabetes mellitus improves pregnancy outcomes...
  51. ncbi Identifying risk for obesity in early childhood
    Philip R Nader
    Division of Community Pediatrics, University of California, San Diego, California, USA
    Pediatrics 118:e594-601. 2006
    ..Our aim with this study was to assist clinicians by estimating the predictive value of earlier levels of BMI status on later risk of overweight and obesity during the middle childhood and early adolescent years...
  52. pmc Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study
    Gillian K Reeves
    Cancer Epidemiology Unit, University of Oxford, Oxford OX3 7LF
    BMJ 335:1134. 2007
    To examine the relation between body mass index (kg/m2) and cancer incidence and mortality.
  53. doi Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis
    Crystal Man Ying Lee
    Nutrition and Lifestyle Division, The George Institute for International Health, University of Sydney, PO Box M 201, Missenden Road, Sydney NSW 2050, Australia
    J Clin Epidemiol 61:646-53. 2008
    ..To determine which simple index of overweight and obesity is the best discriminator of cardiovascular risk factors...
  54. pmc A new highly penetrant form of obesity due to deletions on chromosome 16p11.2
    R G Walters
    Section of Genomic Medicine, Imperial College London, London W12 0NN, UK
    Nature 463:671-5. 2010
    ..7% of our morbid obesity cases (body mass index (BMI) >or= 40 kg m(-2) or BMI standard deviation score >or= 4; P = 6.4 x 10(-8), odds ratio 43...
  55. ncbi Using pedometers to increase physical activity and improve health: a systematic review
    Dena M Bravata
    Center for Primary Care and Outcomes Research, Stanford University, Stanford, California, USA
    JAMA 298:2296-304. 2007
    ..Without detailed evidence of their effectiveness, pedometers have recently become popular as a tool for motivating physical activity...
  56. ncbi Genetic and environmental factors in relative body weight and human adiposity
    H H Maes
    Virginia Institute for Psychiatric and Behavioral Genetics, Richmond, Virginia 23298, USA
    Behav Genet 27:325-51. 1997
    We review the literature on the familial resemblance of body mass index (BMI) and other adiposity measures and find strikingly convergent results for a variety of relationships...
  57. ncbi Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the U.S
    Earl S Ford
    Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Diabetes Care 28:2745-9. 2005
    ..S. adults and to compare it with the prevalence estimated using the definition of the National Cholesterol Education Program (NCEP)...
  58. ncbi Fasting serum glucose level and cancer risk in Korean men and women
    Sun Ha Jee
    Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Korea
    JAMA 293:194-202. 2005
    ..Diabetes is a serious and costly disease that is becoming increasingly common in many countries. The role of diabetes as a cancer risk factor remains unclear...
  59. pmc Proximity to food establishments and body mass index in the Framingham Heart Study offspring cohort over 30 years
    Jason P Block
    Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, 133 Brookline Avenue, Boston, MA 02215, USA
    Am J Epidemiol 174:1108-14. 2011
    Existing evidence linking residential proximity to food establishments with body mass index (BMI; weight (kg)/height (m)(2)) has been inconclusive...
  60. ncbi Health-related quality of life of severely obese children and adolescents
    Jeffrey B Schwimmer
    Division of Pediatric Gastroenterology, Hepatology, and Nutrition, School of Medicine, University of California, San Diego 92103, USA
    JAMA 289:1813-9. 2003
    ..One in 7 US children and adolescents is obese, yet little is known about their health-related quality of life (QOL)...
  61. pmc Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients
    Fabrice Armougom
    URMITE UMR CNRS 6236, IRD 3R198, Universite de la Mediterranee, Faculte de Medecine, and Nutrition and Diabetology Department, University Hospital Sainte Marguerite, Marseille, France
    PLoS ONE 4:e7125. 2009
    ..The roles of the archaeon Methanobrevibacter smithii and Lactobacillus species have not been described in these studies...
  62. pmc Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
    Angelo Scuteri
    Unità Operativa Geriatria, Istituto per la Patologia Endocrina e Metabolica, Rome, Italy
    PLoS Genet 3:e115. 2007
    ..These changes could have a significant impact on the risk of obesity-related morbidity in the general population...
  63. ncbi Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
    K Hotta
    Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University, Osaka, Japan
    Arterioscler Thromb Vasc Biol 20:1595-9. 2000
    ..We analyzed the plasma adiponectin concentrations in age- and body mass index (BMI)-matched nondiabetic and type 2 diabetic subjects with and without coronary artery disease (CAD)...
  64. ncbi Updated definitions of healthy ranges for serum alanine aminotransferase levels
    Daniele Prati
    Centro Trasfusionale e di Immunologia dei Trapianti, Laboratorio di Epidemiologia, Divisione di Ematologia, Istituto di Statistica Medica e Biometria, Cattedra di Gastroenterologia, Milan, Italy
    Ann Intern Med 137:1-10. 2002
    ..Current standards for "normal" ALT level were defined by using populations that included persons with subclinical liver disease...
  65. ncbi The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease
    Bartolome R Celli
    COPD Center at St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, MA 02135, USA
    N Engl J Med 350:1005-12. 2004
    ..We hypothesized that a multidimensional grading system that assessed the respiratory and systemic expressions of COPD would better categorize and predict outcome in these patients...
  66. ncbi Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
    Samar I Itani
    Diabetes Unit, Section of Endocrinology, Department of Medicine, Boston University Medical Center, Boston, MA, USA
    Diabetes 51:2005-11. 2002
    ..Whether acute FFA-induced insulin resistance in human skeletal muscle is caused by the activation of these specific PKC isoforms and the IKK-beta/IkappaB/NFkappaB pathway remains to be established...
  67. ncbi Decreased plasma adiponectin concentrations in women with dyslipidemia
    Miyao Matsubara
    Division of Endocrinology and Metabolism, Internal Medicine, Otaru City General Hospital, Wakamutsu 1 2 1, Otaru 047 8550, Japan
    J Clin Endocrinol Metab 87:2764-9. 2002
    ..and apolipoprotein (apo) levels in 352 nondiabetic women, 16-86 yr old, with a wide range of body weight [body mass index (BMI), 14.8-36.3 kg/m(2)]. Plasma adiponectin concentrations in women with the highest tertile of TG (1...
  68. ncbi Validity of self-reported height and weight in 4808 EPIC-Oxford participants
    Elizabeth A Spencer
    Imperial Cancer Research Fund Cancer Epidemiology Unit, University of Oxford, Gibson Building, The Radcliffe Infirmary, UK
    Public Health Nutr 5:561-5. 2002
    ..weight by comparison with measured height and weight in a sample of middle-aged men and women, and to determine the extent of misclassification of body mass index (BMI) arising from differences between self-reported and measured values.
  69. ncbi Reducing children's television viewing to prevent obesity: a randomized controlled trial
    T N Robinson
    Department of Pediatrics, Stanford Center for Research in Disease Prevention, Stanford University School of Medicine, Palo Alto, Calif 94304, USA
    JAMA 282:1561-7. 1999
    ..Some observational studies have found an association between television viewing and child and adolescent adiposity...
  70. ncbi Long-term weight loss maintenance
    Rena R Wing
    Brown Medical School, The Miriam Hospital, Department of Psychiatry, Providence, RI, USA
    Am J Clin Nutr 82:222S-225S. 2005
    ..National Weight Control Registry members provide evidence that long-term weight loss maintenance is possible and help identify the specific approaches associated with long-term success...
  71. doi Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype
    Sofia Inez Iqbal Kring
    Institute of Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark
    Obes Facts 1:138-45. 2008
    ..In the present study, we assess the association of seven abdominal, peripheral, and overall obesity phenotypes, which were analyzed quantitatively, and thirteen candidate gene polymorphisms in these ten genes in the same cohort...
  72. ncbi Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, controlled trials
    Seamus P Whelton
    Tulane University, New Orleans, Louisiana 70112, USA
    Ann Intern Med 136:493-503. 2002
    ..This meta-analysis of randomized, controlled trials was conducted to determine the effect of aerobic exercise on blood pressure...
  73. pmc Gene X environment interaction of vigorous exercise and body mass index among male Vietnam-era twins
    Jeanne M McCaffery
    Weight Control and Diabetes Research Center, Brown Medical School and The Miriam Hospital, Providence, RI 02903, USA
    Am J Clin Nutr 89:1011-8. 2009
    Secular trends over the past several decades suggest an environmental influence on body mass index (BMI)...
  74. ncbi Variation in FTO contributes to childhood obesity and severe adult obesity
    Christian Dina
    CNRS 8090 Institute of Biology, Pasteur Institute, Lille, France
    Nat Genet 39:724-6. 2007
    ..The at-risk haplotype yields a proportion of attributable risk of 22% for common obesity. We conclude that FTO contributes to human obesity and hence may be a target for subsequent functional analyses...
  75. ncbi Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease
    James B Meigs
    General Medicine Division, Massachusetts General Hospital, 50 Staniford Street, 9th Floor, Boston, MA 02114, USA
    J Clin Endocrinol Metab 91:2906-12. 2006
    ..Metabolic risk conferred by adiposity may be due to associated risk factor clustering...
  76. pmc Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups
    Andre Scherag
    Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg Essen, Essen, Germany
    PLoS Genet 6:e1000916. 2010
    ..We conclude that the currently known major common variants related to obesity overlap to a substantial degree between children and adults...
  77. ncbi Waist circumference, waist-hip ratio and body mass index and their correlation with cardiovascular disease risk factors in Australian adults
    M Dalton
    International Diabetes Institute, Melbourne, Caulfield, Victoria, Australia
    J Intern Med 254:555-63. 2003
    To compare body mass index (BMI), waist circumference and waist-hip ratio (WHR) as indices of obesity and assess the respective associations with type 2 diabetes, hypertension and dyslipidaemia.
  78. ncbi Asians are different from Caucasians and from each other in their body mass index/body fat per cent relationship
    P Deurenberg
    Wageningen University, The Netherlands
    Obes Rev 3:141-6. 2002
    The objective was to study the relationship between body mass index (BMI) and body fat per cent (BF%) in different population groups of Asians. The study design was a literature overview with special attention to recent Asian data...
  79. ncbi BMI-referenced standards for recommended pedometer-determined steps/day in children
    Catrine Tudor-Locke
    Department of Exercise and Wellness, Arizona State University East, Mesa, AZ 85212 0180, USA
    Prev Med 38:857-64. 2004
    ..The purpose of the present study was to establish criterion-referenced standards for PA (using pedometer-assessed steps/day) related to healthy body composition...
  80. doi A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
    Yoon Shin Cho
    Center for Genome Science, National Institute of Health, Seoul, Korea
    Nat Genet 41:527-34. 2009
    ..For height and body mass index, most variants detected overlapped those reported in European samples...
  81. ncbi Meta-analysis: the effect of dietary counseling for weight loss
    Michael L Dansinger
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 147:41-50. 2007
    ..Dietary and lifestyle modification efforts are the primary treatments for people who are obese or overweight. The effect of dietary counseling on long-term weight change is unclear...
  82. ncbi Characteristics of physical activities in daily life in chronic obstructive pulmonary disease
    Fabio Pitta
    Respiratory Rehabilitation and Respiratory Division, University Hospital Gasthuisberg, Herestraat 49, B 3000 Leuven, Belgium
    Am J Respir Crit Care Med 171:972-7. 2005
    ..28 < r < 0.64, p < 0.05). Patients with chronic obstructive pulmonary disease are markedly inactive in daily life. Functional exercise capacity is the strongest correlate of physical activities in daily life...
  83. ncbi Impact of overweight on the risk of developing common chronic diseases during a 10-year period
    A E Field
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, 181 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 161:1581-6. 2001
    ..Overweight adults are at an increased risk of developing numerous chronic diseases...
  84. doi Physical activity attenuates the body mass index-increasing influence of genetic variation in the FTO gene
    Karani S Vimaleswaran
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom
    Am J Clin Nutr 90:425-8. 2009
    Intronic variation in the FTO (fat mass and obesity-associated) gene has been unequivocally associated with increased body mass index (BMI; in kg/m(2)) and the risk of obesity in populations of different ethnicity.
  85. ncbi Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population
    Yong Ho Lee
    Department of Internal Medicine, Yonsei University College of Medicine, 134 Shinchon dong Seodaemun gu, Seoul 120 752, South Korea
    J Hum Genet 53:991-8. 2008
    ..rs1111875, rs10811661, rs4402960, rs8050136, rs734312, rs7754840 and rs2237892 and measured the body weight, body mass index and fasting plasma glucose in all patients and controls...
  86. ncbi The effects of maternal body mass index on pregnancy outcome
    A S Khashan
    The Anu Research Centre, Department of Obstetrics and Gynaecology, Cork University Maternity Hospital, University College Cork, Wilton, Cork, Ireland
    Eur J Epidemiol 24:697-705. 2009
    ..We examined the effect of Body Mass Index in early pregnancy on adverse pregnancy outcome...
  87. ncbi The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis
    Kerstin Wahlen
    Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    J Lipid Res 49:607-11. 2008
    ..in relation to fat cell function and adipose tissue gene expression in 306 healthy women with a wide range in body mass index (18-53 kg/m(2))...
  88. ncbi Waist circumference and waist-to-height ratio are better predictors of cardiovascular disease risk factors in children than body mass index
    S C Savva
    Research and Education Program of Child Health, Cyprus
    Int J Obes Relat Metab Disord 24:1453-8. 2000
    ..Waist measurement and waist-to-height ratio (WHtR) have been used as proxy measures of visceral adipose tissue, mainly in adults...
  89. doi Risk factors for childhood overweight: shift of the mean body mass index and shift of the upper percentiles: results from a cross-sectional study
    A Beyerlein
    Ludwig Maximilians University of Munich, Institute of Social Paediatrics and Adolescent Medicine, Division of Epidemiology, Munich, Germany
    Int J Obes (Lond) 34:642-8. 2010
    ..increasing prevalence of childhood overweight seems to be due to an increasing proportion of extremely high body mass index (BMI) values rather than to a shift of the entire BMI distribution...
  90. ncbi Structural brain differences and cognitive functioning related to body mass index in older females
    Katrin Walther
    Department of Psychology, University of Arizona, Tucson, Arizona 85721 0068, USA
    Hum Brain Mapp 31:1052-64. 2010
    ..This study examined the association between body mass index (BMI), regional volume differences in gray and white matter measured by magnetic resonance imaging (MRI), and ..
  91. doi Body mass index, waist circumference and waist:hip ratio as predictors of cardiovascular risk--a review of the literature
    R Huxley
    Renal and Metabolic Division, The George Institute for International Health, The University of Sydney, Sydney, Australia
    Eur J Clin Nutr 64:16-22. 2010
    ..Traditionally, body mass index (BMI) has been the most widely used method by which to determine the prevalence of overweight in, and across, ..
  92. pmc Common body mass index-associated variants confer risk of extreme obesity
    Chris Cotsapas
    Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA
    Hum Mol Genet 18:3502-7. 2009
    ..We also found evidence of association at a further six of 12 other loci previously reported to influence body mass index (BMI) in the general population and one of three associations to severe childhood and adult obesity and that ..
  93. ncbi Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance
    W Timothy Garvey
    Division of Endocrinology and Department of Medicine, Medical University of South Carolina, Charleston 29425, USA
    Diabetes 52:453-62. 2003
    ..It will be important to study whether NMR lipoprotein subclass parameters can be used to manage risk more effectively and prevent cardiovascular disease in patients with the IRS...
  94. ncbi Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study
    Caroline S Fox
    National Heart, Lung and Blood Institute s Framingham Heart Study, Framingham, Mass, USA
    Circulation 116:39-48. 2007
    ..The incremental utility of measuring both visceral and subcutaneous abdominal adipose tissue (SAT) in association with metabolic risk factors and underlying heritability has not been well described in a population-based setting...
  95. ncbi The prevalence and impact of overweight and obesity in an Australian obstetric population
    Leonie K Callaway
    E Floor, Clinical Sciences Building, Royal Brisbane and Women s Hospital, Herston QLD 4029, Australia
    Med J Aust 184:56-9. 2006
    ..To assess the prevalence and impact of overweight and obesity in an Australian obstetric population...
  96. pmc Gestational weight gain and child adiposity at age 3 years
    Emily Oken
    Obesity Prevention Program, Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Am J Obstet Gynecol 196:322.e1-8. 2007
    ..The purpose of this study was to examine the associations of gestational weight gain with child adiposity...
  97. ncbi Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002
    Allison A Hedley
    Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA
    JAMA 291:2847-50. 2004
    ..The prevalence of overweight and obesity has increased markedly in the last 2 decades in the United States...
  98. ncbi Obesity, obstetric complications and cesarean delivery rate--a population-based screening study
    Joshua L Weiss
    Division of Maternal Fetal Medicine, Columbia Presbytrian Medical Center, New York, NY 10032, USA
    Am J Obstet Gynecol 190:1091-7. 2004
    ..This study was undertaken to determine whether obesity is associated with obstetric complications and cesarean delivery...
  99. ncbi Fetal origins of adult disease: strength of effects and biological basis
    D J P Barker
    Medical Research Council Environmental Epidemiology Unit, Southampton SO16 6YD, UK
    Int J Epidemiol 31:1235-9. 2002
    ....
  100. doi Relationship between body mass index and gray matter volume in 1,428 healthy individuals
    Yasuyuki Taki
    Department of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer IDAC, Tohoku University, Sendai, Japan
    Obesity (Silver Spring) 16:119-24. 2008
    ....
  101. ncbi Anthropometric determinants of a clustering of lipid-related metabolic risk factors in overweight and non-overweight adolescents--influence of cardiorespiratory fitness. The Avena study
    Jose L Mesa
    Department of Medical Physiology, School of Medicine, University of Granada, Granada, Spain
    Ann Nutr Metab 50:519-27. 2006
    ....

Research Grants90

  1. Weight management for improved pregnancy outcomes
    Victor J Stevens; Fiscal Year: 2010
    ..More than 1/3 of women in the U.S. are now starting their pregnancies with a body mass index or 30 or greater, a condition that was unusual to rare 50 years ago...
  2. Sleep deprivation and energy balance
    Marie Pierre St Onge; Fiscal Year: 2009
    ..correlates with overweight and obesity, such that individuals with short sleep periods tend to have a higher body mass index (BMI) than those who sleep 8-9 h/night. The mechanism for this relationship is currently unknown...
  3. SEER RRSS #4: Cancer in Arab American Estimating Rates and Fostering Research
    Ann Schwartz; Fiscal Year: 2009
    ..indicate there is an increase in behavioral risk factors, particularly physical inactivity and increased body mass index, which may increase cancer risk. A.2...
  4. Pharmacogenetics of obesity and endocannabinergic modulation (POEM)
    Russell A Wilke; Fiscal Year: 2009
    ..test tagSNPs in each of these candidate eCB/CB1 signaling genes for association with 12 quantitative traits: body mass index (BMI), waist circumference, hip circumference, waist/hip ratio (WHR), fasting glucose, insulin, insulin/..
  5. Pharmacogenetics of obesity and endocannabinergic modulation (POEM)
    RUSSELL WILKE; Fiscal Year: 2009
    ..test tagSNPs in each of these candidate eCB/CB1 signaling genes for association with 12 quantitative traits: body mass index (BMI), waist circumference, hip circumference, waist/hip ratio (WHR), fasting glucose, insulin, insulin/..
  6. Pharmacogenetics of obesity and endocannabinergic modulation (POEM)
    Russell A Wilke; Fiscal Year: 2010
    ..test tagSNPs in each of these candidate eCB/CB1 signaling genes for association with 12 quantitative traits: body mass index (BMI), waist circumference, hip circumference, waist/hip ratio (WHR), fasting glucose, insulin, insulin/..
  7. Effective treatment of sleep apnea in prediabetes to reduce cardiometabolic risk
    Esra Tasali; Fiscal Year: 2009
    ..between OSA and insulin resistance, glucose intolerance and the risk of diabetes, independently of body mass index. In an analysis of over 2500 non- diabetic individuals, the presence of OSA was associated with a ..
  8. Effective treatment of sleep apnea in prediabetes to reduce cardiometabolic risk
    Esra Tasali; Fiscal Year: 2010
    ..between OSA and insulin resistance, glucose intolerance and the risk of diabetes, independently of body mass index. In an analysis of over 2500 non- diabetic individuals, the presence of OSA was associated with a ..
  9. Genetic Instability & Risk for Esophageal Carcinoma
    Xifeng Wu; Fiscal Year: 2009
    ..profiles will be obtained by personal interview on smoking history, alcohol consumption, dietary intake, body mass index (BMI), physical activity, cancer family history, occupational exposures, previous medical history, and ..
  10. The Effect of Behavioral and Physiological Factors on Obesity Risk in Children
    Karen B Dorsey; Fiscal Year: 2010
    ..Study participants will be non-obese 7 - to 9- year old children with a body mass index above the 50th percentile for age and gender in order to identify early clinical indicators of increased risk ..
  11. Chronic stress mediates fat-related changes in insulin signaling and gut motility
    Charalabos Pothoulakis; Fiscal Year: 2009
    ..Furthermore, changes in body fat observed in obesity, or changes in body mass index (as observed in patients suffering from functional gastrointestinal disorders) have been associated with ..
  12. Chronic stress mediates fat-related changes in insulin signaling and gut motility
    CHARALABOS contact POTHOULAKIS; Fiscal Year: 2010
    ..Furthermore, changes in body fat observed in obesity, or changes in body mass index (as observed in patients suffering from functional gastrointestinal disorders) have been associated with ..
  13. Dietary supplement use, physical activity, body mass index, and pancreatic cancer
    Ka He; Fiscal Year: 2010
    ..iron, gingko biloba) and non- steroidal anti-inflammatory drugs (NSAIDs);as well as physical activity and body mass index levels at baseline and ages 18, 30, and 45 years with pancreatic cancer incidence...
  14. Dietary supplement use, physical activity, body mass index, and pancreatic cancer
    Jessie Satia; Fiscal Year: 2009
    ..iron, gingko biloba) and non- steroidal anti-inflammatory drugs (NSAIDs);as well as physical activity and body mass index levels at baseline and ages 18, 30, and 45 years with pancreatic cancer incidence...
  15. Who benefits from Colorectal Cancer Screening? A subgroup Analysis of the Minnes
    Aasma Shaukat; Fiscal Year: 2009
    ..We also wish to evaluate the influence of baseline characteristics, such as diet, aspirin use and body mass index on these outcomes...
  16. Non-Hodgkin lymphoma in women: reproductive, hormonal and genetic factors
    Paige M Bracci; Fiscal Year: 2010
    ..Risk of NHL also has been associated with increased body mass index (BMI) and some autoimmune conditions with each in turn associated with levels and circulation of sex- ..
  17. Mediators of Atherosclerosis in South Asians Living in America
    Alka M Kanaya; Fiscal Year: 2010
    ..of atherosclerosis, diabetes, hypertension, and cardiovascular disease in this ethnic group, despite low body mass index. However, there are no longitudinal studies of South Asians to determine other risk factors that may explain ..
  18. Television Advertising and Children's Diet Activity and Obesity Prevalence
    Lisa Powell; Fiscal Year: 2010
    ..service healthy diet and physical activity (HDPA) health promotion messages, and diet, physical activity, body mass index (BMI) and obesity among children and youth. The overwhelming majority (97...
  19. Weight management for improved pregnancy outcomes
    Victor Stevens; Fiscal Year: 2009
    ..More than 1/3 of women in the U.S. are now starting their pregnancies with a body mass index or 30 or greater, a condition that was unusual to rare 50 years ago...
  20. Prospective Study of Diet, Physical Activity, BMI and Risk of Pulmonary Embolism
    Carlos Camargo; Fiscal Year: 2007
    ..observational cohort studies to examine the relationship between dietary factors, physical activity, body mass index (BMI) and risk of PE among elderly participants in the Nurses' Health Study (NHS) and the Health ..
  21. HCV TREATMENT IN AFRICAN AMERICANS VS NON HISPANIC WHIT*
    Lennox Jeffers; Fiscal Year: 2004
    ..treatment and week 24 post-treatment) response patterns, as well as, hepatic histology activity index (HAI), Body Mass Index (BMI) and demographic (e.g., age, gender, education, income level) and psychosocial factors (e.g...
  22. HYPERINSULINEMIA AND HYPERTENSION IN OVERWEIGHT MEN
    Brent Egan; Fiscal Year: 1991
    ..Three studies test three related hypotheses: (1) The threefold higher prevalence of Ht in obese (body mass index >27kg/m2) younger men, vs. age-matched normal weight (BMI <25...
  23. Exercise-Facilitated NeuroRehabilitation in Diabetic Neuropathy
    EVAN STUBBS; Fiscal Year: 2009
    ..The prevalence of type 2 diabetes has conservatively tripled in the last 30 years. Individuals with a body mass index (BMI) of 30 or more have a 5-fold greater risk of diabetes compared to subjects with BMI of 25 or less...
  24. EPIDEMIC HYPERTENSION IN NIGERIAN WORKERS
    Clareann Bunker; Fiscal Year: 1999
    ..Smaller differences were observed by staff status in females. Mean body mass index (BMI) was very low in the males (22.9 in Senior and 21.4 in Junior staff) and low in females (25...
  25. Risk Factors and Potential Protective Medications for Parkinson Disease
    David Sparrow; Fiscal Year: 2009
    ..among veterans of the Vietnam War is predicted by exposure to herbicides, lower cholesterol, diabetes, higher body mass index (BMI), and use of statins (3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors), non-steroidal anti-..
  26. Antidepressant Treatment and Risk of Obesity
    DAVID ERIC ARTERBURN; Fiscal Year: 2010
    ..In 2002, the prevalence of obesity (defined as a body mass index [BMI, calculated as weight in kilograms divided by the square of height in meters] of e 30) among US adults ..
  27. Antidepressant Treatment and Risk of Obesity
    David Arterburn; Fiscal Year: 2009
    ..In 2002, the prevalence of obesity (defined as a body mass index [BMI, calculated as weight in kilograms divided by the square of height in meters] of e 30) among US adults ..
  28. METABOLICALLY NORMAL AND ABNORMAL OBESITY
    Samuel Klein; Fiscal Year: 2010
    ..in liver, muscle and adipose tissue and increased VLDL-triglyceride [VLDL-TG] secretion rate), independent of body mass index (BMI), percent body fat, and visceral fat mass...
  29. Memory, Thiamine Levels, and Brain Structure in Heart Failure
    Mary Woo; Fiscal Year: 2009
    ..thiamine levels, short-term memory, and mammillary body volumes and clinical characteristics (age, LVEF, body mass index, number of re-hospitalizations for HF in 6 months)...
  30. Adipokines in Hemodialysis Patients
    Srinivasan Beddhu; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): In contrast to the non-uremic population, high body mass index (BMI) has been shown to be associated with better survival in dialysis patients and hence fat is considered to be beneficial in dialysis ..
  31. Adipokines in Hemodialysis Patients
    Srinivasan Beddhu; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): In contrast to the non-uremic population, high body mass index (BMI) has been shown to be associated with better survival in dialysis patients and hence fat is considered to be beneficial in dialysis ..
  32. Can diet- & exercise-induced weight loss improve asthma control in obese adults?
    Jun Ma; Fiscal Year: 2009
    ..We will randomize 324 patients ages 18-70 years who have suboptimally controlled, persistent asthma and a body mass index of 30.0 to 39...
  33. Can diet- & exercise-induced weight loss improve asthma control in obese adults?
    Jun Ma; Fiscal Year: 2009
    ..We will randomize 324 patients ages 18-70 years who have suboptimally controlled, persistent asthma and a body mass index of 30.0 to 39...
  34. Can diet- & exercise-induced weight loss improve asthma control in obese adults?
    Jun Ma; Fiscal Year: 2009
    ..We will randomize 324 patients ages 18-70 years who have suboptimally controlled, persistent asthma and a body mass index of 30.0 to 39...
  35. Cardiometabolic Risk Factors and Obesity in Adolescents with Down Syndrome
    Sheela Natesh Magge; Fiscal Year: 2012
    ..Aims: 1) To compare the relationship between body mass index and adiposity (measured by DXA), and cardiometabolic risk factors (non-HDL cholesterol, lipoprotein subclass ..
  36. Biopsychosocial approaches to healthy aging
    Terrie Vasilopoulos; Fiscal Year: 2011
    ..Physical function measures include blood pressure, body mass index, and medication...
  37. Genetic Architecture of Adiposity in Multiple Large Cohorts
    Kari E North; Fiscal Year: 2010
    ..5% of trait variance. We propose to extend the meta-analysis approach of these cohorts to investigate body mass index (BMI, wt/ht2), waist circumference (WC), waist-hip ratio (WHR), obesity (BMI>30 kg/m2) and extreme obesity ..
  38. Behavioral Family Systems Therapy for Teens with Type 2 Diabetes: A Pilot
    LISA MARIE BUCKLOH; Fiscal Year: 2010
    ..Areas targeted for improvement will include metabolic control, weight/body mass index, treatment adherence, family lifestyle choices (activity, diet), family communication, and problem solving...
  39. Neighborhood Environments and Disparities in Obesity Rates in New York City
    Andrew G Rundle; Fiscal Year: 2010
    ..that neighborhood characteristics such as urban design features and neighborhood socioeconomic status predict body mass index (BMI)...
  40. Endometrial cancer chemoprevention strategy for obese wo
    Karen Lu; Fiscal Year: 2003
    ..affected by obesity: 37% of African American women and 33% of Mexican American women are obese (body mass index equal to or more than 30 kg/m2)...
  41. Economic Contextual Influences on Population Diet and Obesity
    Lisa Powell; Fiscal Year: 2009
    ..and chips), beverage (soda) and restaurant state sales taxes and food consumption patterns, diet quality, body mass index (BMI) and obesity prevalence among children, adolescents, and adults...
  42. Hypothalamic Deep Brain Stimulation for Morbid Obesity:Development of a Pig Model
    William Melega; Fiscal Year: 2009
    ..and dietary patterns remain critical factors for modulating long term weight control of obese individuals (body mass index, BMI >30), but surgical interventions are often needed to treat morbid obesity (clinically severe, BMI >..
  43. Economic Contextual Influences on Population Diet and Obesity
    Lisa Powell; Fiscal Year: 2010
    ..and chips), beverage (soda) and restaurant state sales taxes and food consumption patterns, diet quality, body mass index (BMI) and obesity prevalence among children, adolescents, and adults...
  44. An analysis of environmental risk factors for obesity
    Walker Poston; Fiscal Year: 2003
    ..In the proposed study, we will collect both individual-level health data including weight and body mass index (BMI), status on other health conditions and behaviors, as well information on the density of social ..
  45. Hypothalamic Deep Brain Stimulation for Morbid Obesity:Development of a Pig Model
    William P Melega; Fiscal Year: 2010
    ..and dietary patterns remain critical factors for modulating long term weight control of obese individuals (body mass index, BMI >30), but surgical interventions are often needed to treat morbid obesity (clinically severe, BMI >..
  46. An analysis of environmental risk factors for obesity
    Walker Poston; Fiscal Year: 2006
    ..In the proposed study, we will collect both individual-level health data including weight and body mass index (BMI), status on other health conditions and behaviors, as well information on the density of social ..
  47. An analysis of environmental risk factors for obesity
    Walker Poston; Fiscal Year: 2004
    ..In the proposed study, we will collect both individual-level health data including weight and body mass index (BMI), status on other health conditions and behaviors, as well information on the density of social ..
  48. An analysis of environmental risk factors for obesity
    Walker Poston; Fiscal Year: 2005
    ..In the proposed study, we will collect both individual-level health data including weight and body mass index (BMI), status on other health conditions and behaviors, as well information on the density of social ..
  49. An analysis of environmental risk factors for obesity
    Walker Poston; Fiscal Year: 2007
    ..In the proposed study, we will collect both individual-level health data including weight and body mass index (BMI), status on other health conditions and behaviors, as well information on the density of social ..
  50. An analysis of environmental risk factors for obesity
    Walker Poston; Fiscal Year: 2004
    ..In the proposed study, we will collect both individual-level health data including weight and body mass index (BMI), status on other health conditions and behaviors, as well information on the density of social ..
  51. DIETARY COMPOSITION, OBESITY, AND CARDIOVASCULAR RISK
    ERNST SCHAEFER; Fiscal Year: 2003
    ..of age, women postmenopausal and less than 65) with LDL C values greater than or equal to 130 mg/dI and a body mass index greater than or equal to 28 and less than 38 kg/m2...
  52. DIETARY COMPOSITION, OBESITY, AND CARDIOVASCULAR RISK
    ERNST SCHAEFER; Fiscal Year: 2001
    ..of age, women postmenopausal and less than 65) with LDL C values greater than or equal to 130 mg/dI and a body mass index greater than or equal to 28 and less than 38 kg/m2...
  53. Sleep deprivation and energy balance
    Marie Pierre St Onge; Fiscal Year: 2009
    ..correlates with overweight and obesity, such that individuals with short sleep periods tend to have a higher body mass index (BMI) than those who sleep 8-9 h/night. The mechanism for this relationship is currently unknown...
  54. DIETARY COMPOSITION, OBESITY, AND CARDIOVASCULAR RISK
    ERNST SCHAEFER; Fiscal Year: 2000
    ..of age, women postmenopausal and less than 65) with LDL C values greater than or equal to 130 mg/dI and a body mass index greater than or equal to 28 and less than 38 kg/m2...
  55. DIETARY COMPOSITION, OBESITY, AND CARDIOVASCULAR RISK
    ERNST SCHAEFER; Fiscal Year: 2002
    ..of age, women postmenopausal and less than 65) with LDL C values greater than or equal to 130 mg/dI and a body mass index greater than or equal to 28 and less than 38 kg/m2...
  56. DIETARY COMPOSITION, OBESITY, AND CARDIOVASCULAR RISK
    ERNST SCHAEFER; Fiscal Year: 1999
    ..of age, women postmenopausal and less than 65) with LDL C values greater than or equal to 130 mg/dI and a body mass index greater than or equal to 28 and less than 38 kg/m2...
  57. Sleep deprivation and energy balance
    Marie Pierre St Onge; Fiscal Year: 2010
    ..correlates with overweight and obesity, such that individuals with short sleep periods tend to have a higher body mass index (BMI) than those who sleep 8-9 h/night. The mechanism for this relationship is currently unknown...
  58. Efficacy of Optimal Levels of Dietary Dairy on Modulation of Adolescent Weight
    Joan Lappe; Fiscal Year: 2009
    ..We propose a 1-year intervention in 13- and 14-year old girls who are above the 50th percentile for body mass index (BMI) and are at least 1= years post- menarche to determine if we can prevent excessive BF gain...
  59. HYPOTHALAMIC CONTROL OF FEEDING AND METABOLISM
    ROGER CONE; Fiscal Year: 2002
    ..Obesity, as defined by a body mass index above 25, increased from an incidence of 24% in 1980 to 33% in 1990 in a large representative sample in the ..
  60. HYPOTHALAMIC CONTROL OF FEEDING AND METABOLISM
    ROGER CONE; Fiscal Year: 2001
    ..Obesity, as defined by a body mass index above 25, increased from an incidence of 24% in 1980 to 33% in 1990 in a large representative sample in the ..
  61. HYPOTHALAMIC CONTROL OF FEEDING AND METABOLISM
    ROGER CONE; Fiscal Year: 2003
    ..Obesity, as defined by a body mass index above 25, increased from an incidence of 24% in 1980 to 33% in 1990 in a large representative sample in the ..
  62. HYPOTHALAMIC CONTROL OF FEEDING AND METABOLISM
    ROGER CONE; Fiscal Year: 2001
    ..Obesity, as defined by a body mass index above 25, increased from an incidence of 24% in 1980 to 33% in 1990 in a large representative sample in the ..
  63. HYPOTHALAMIC CONTROL OF FEEDING AND METABOLISM
    ROGER CONE; Fiscal Year: 2000
    ..Obesity, as defined by a body mass index above 25, increased from an incidence of 24% in 1980 to 33% in 1990 in a large representative sample in the ..
  64. HYPOTHALAMIC CONTROL OF FEEDING AND METABOLISM
    ROGER CONE; Fiscal Year: 1999
    ..Obesity, as defined by a body mass index above 25, increased from an incidence of 24% in 1980 to 33% in 1990 in a large representative sample in the ..
  65. HYPOTHALAMIC CONTROL OF FEEDING AND METABOLISM
    ROGER CONE; Fiscal Year: 2001
    ..Obesity, as defined by a body mass index above 25, increased from an incidence of 24% in 1980 to 33% in 1990 in a large representative sample in the ..
  66. Experimental analysis of price changes and food purchases in obese and lean mothe
    Leonard H Epstein; Fiscal Year: 2010
    ..The goal of this application is to study whether income, body mass index (BMI), relative reinforcing value of food (RRV) and impulsivity moderate the effects of prices on energy and ..
  67. Neighborhood Environments and Disparities in Obesity Rates in New York City
    Andrew Rundle; Fiscal Year: 2009
    ..that neighborhood characteristics such as urban design features and neighborhood socioeconomic status predict body mass index (BMI)...
  68. METABOLISM, MICRONUTRIENTS, AND ANTIRETROVIRAL THERAPY OUTCOMES IN ZAMBIA
    DOUGLAS HEIMBURGER; Fiscal Year: 2009
    ..Lusaka, Zambia (CIDRZ) and who exhibit high risk for early ART mortality (CD4+ count < 50 cells/<L or body mass index [BMI] < 16 kg/m2)...
  69. Role of thermoregulatory leptin action via the DMH in body weight control
    KAVON PAUL REZAI-ZADEH; Fiscal Year: 2012
    ..Having a body mass index (BMI) >30 kg/m2 clinically defines an individual as obese and significantly increases that individual'..
  70. Impact of Malnutrition on HIV Treatment Failure in Resource-Limited Settings
    Amita Gupta; Fiscal Year: 2010
    ..Early treatment failure is associated with low CD4 count, low body mass index, and anemia, but these markers are nonspecific and could reflect advanced HIV, co-infections, and/or ..
  71. Impact of Malnutrition on HIV Treatment Failure in Resource-Limited Settings
    Amita Gupta; Fiscal Year: 2009
    ..Early treatment failure is associated with low CD4 count, low body mass index, and anemia, but these markers are nonspecific and could reflect advanced HIV, co-infections, and/or ..
  72. Chicago Healthy Aging Low Risk MRI Angiography (CHARISMA) Study
    Donald Lloyd Jones; Fiscal Year: 2009
    ..CVD), defined by no smoking, lack of diabetes, low total cholesterol levels, low blood pressure, and lean body mass index. Compared with individuals with not-LR status, those with LR status in young adulthood/middle age (<50 ..
  73. Chicago Healthy Aging Low Risk MRI Angiography (CHARISMA) Study
    DONALD M contact LLOYD JONES; Fiscal Year: 2010
    ..CVD), defined by no smoking, lack of diabetes, low total cholesterol levels, low blood pressure, and lean body mass index. Compared with individuals with not-LR status, those with LR status in young adulthood/middle age (<50 ..
  74. Impact of HIV, Antiretroviral Therapy and TB Genotype on Survival in MDR TB
    NEEL RAJNIKANT GANDHI; Fiscal Year: 2010
    ..Similarly, certain host factors, such as disseminated TB, immunosuppression, or low body mass index, which are more common in HIV, are independently associated with poor MDR TB outcomes and may worsen survival ..
  75. A randomized trial of bariatric surgery for the treatment of sleep apnea
    Sanjay R Patel; Fiscal Year: 2010
    ..We will recruit 80 patients with severe OSA and morbid obesity (body mass index, BMI, of 35-40 kg/m2) from two large clinical sleep programs that together care for a wide spectrum and ..
  76. Novel Anti-Obesity Drugs Targeting Fat Processing Pathway
    Henry Pelish; Fiscal Year: 2009
    ..The FDA-approved lipase inhibitor Orlistat prevents fat processing in the gut, leading to reduced body mass index in obese patients. The unprocessed fats are not absorbed by the body and pass through the digestive tract...
  77. Primary Prevention of Weight Gain for Women Aged 25-45
    Walter Willett; Fiscal Year: 2002
    ..Overweight (BMI (Body Mass Index) 25.0-29...
  78. Primary Prevention of Weight Gain for Women Aged 25-45
    Walter Willett; Fiscal Year: 2004
    ..Overweight (BMI (Body Mass Index) 25.0-29...
  79. Primary Prevention of Weight Gain for Women Aged 25-45
    Walter Willett; Fiscal Year: 2003
    ..Overweight (BMI (Body Mass Index) 25.0-29...
  80. Amino Acids, Protein, and BMI in Adults Across Cultures
    Ka He; Fiscal Year: 2007
    ..associations, cross-sectional or longitudinal, between intakes of specific amino acids (AA) or protein and body mass index (BMI)...
  81. Biobehavioral Cardiovascular Health Promotion Intervention in a State Prison Syst
    Debra Moser; Fiscal Year: 2009
    ..Mortality Risk Index [a composite index that includes heart rate, blood pressure, diabetes, smoking status, body mass index, age, and cardio-respiratory fitness], lipid profile, and modifiable lifestyle behaviors) in 4 Kentucky ..
  82. Aminosterol MSI-1436 as a Therapeutic for Obesity
    Michael McLane; Fiscal Year: 2004
    ..Today, 64.5 percent of adult Americans (about 127 million) are categorized as being overweight (body mass index >25) or obese (body mass index >30)...
  83. MOLECULAR MECHANISMS AND MODULATION OF GLIAL ACTIVATION
    Linda Van Eldik; Fiscal Year: 2009
    ..The proportion of children exceeding the 95lh and 85vhpercentiles for body mass index (BMI) is among the greatest in Mexican-Americans...
  84. Technology to Improve Assessment of Physical Activity
    John Jakicic; Fiscal Year: 2005
    ..body size impact the accuracy of the KAL-X Sensor, we will recruit equal numbers of men and women from three body mass index categories (20-24.9 kg/m 2, 25-29.9 kg/m 2, 30-35 kg/m2)...
  85. Technology to Improve Assessment of Physical Activity
    John Jakicic; Fiscal Year: 2004
    ..body size impact the accuracy of the KAL-X Sensor, we will recruit equal numbers of men and women from three body mass index categories (20-24.9 kg/m 2, 25-29.9 kg/m 2, 30-35 kg/m2)...
  86. Neural Mechanisms of Overeating in Prader-Willi Syndrome
    Anastasia Dimitropoulos; Fiscal Year: 2009
    ..caloric value during fasting and post-meal states in individuals with PWS and individuals matched to PWS on body mass index, age, and gender, and (2) to determine the relation between this neural activity and body mass index, food ..
  87. OBESITY PREVENTION IN AMERICAN INDIANS--FIELD CENTER
    Larry Stephenson; Fiscal Year: 1993
    ..center, the early onset of obesity in preadolescent children has increased to alarming levels with the mean body mass index in 8 to 10 year-old children already at or above the 95th percentile for the general U.S. population...
  88. Addressing Health Literacy and Numeracy to Prevent Childhood Obesity
    Russell Rothman; Fiscal Year: 2009
    ..incorrect mixing of infant formula, difficulty understanding food labels and portion sizes, and higher Body Mass Index (BMI) in adults and children...