filtration

Summary

Summary: A process of separating particulate matter from a fluid, such as air or a liquid, by passing the fluid carrier through a medium that will not pass the particulates. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Top Publications

  1. doi Bacterial community structure in the drinking water microbiome is governed by filtration processes
    Ameet J Pinto
    Department of Civil and Environmental Engineering, University of Michigan, USA
    Environ Sci Technol 46:8851-9. 2012
  2. ncbi Use of filter paper for the collection and analysis of human whole blood specimens
    J V Mei
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    J Nutr 131:1631S-6S. 2001
  3. pmc 3D microfilter device for viable circulating tumor cell (CTC) enrichment from blood
    Siyang Zheng
    Department of Bioengineering, Pennsylvania State University, University Park, PA 16802, USA
    Biomed Microdevices 13:203-13. 2011
  4. doi A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma
    Ryan Grant
    Cellular and Molecular Immunology Research Centre, Faculty of Life Sciences, London Metropolitan University, London, UK
    J Immunol Methods 371:143-51. 2011
  5. pmc Air filters and air cleaners: rostrum by the American Academy of Allergy, Asthma & Immunology Indoor Allergen Committee
    James L Sublett
    Department of Pediatrics, Section of Allergy and Immunology, University of Louisville School of Medicine, 9800 Shelbyville Rd, Louisville, KY 40223, USA
    J Allergy Clin Immunol 125:32-8. 2010
  6. doi Flexible graphene films via the filtration of water-soluble noncovalent functionalized graphene sheets
    Yuxi Xu
    Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, People s Republic of China
    J Am Chem Soc 130:5856-7. 2008
  7. doi Effects of water-filtered infrared A irradiation on human fibroblasts
    Tobias Jung
    Institute of Biological Chemistry and Nutrition, University of Hohenheim, Garbenstrasse 28, 70593 Stuttgart, Germany
    Free Radic Biol Med 48:153-60. 2010
  8. pmc Rapid identification of bacteria and yeasts from positive-blood-culture bottles by using a lysis-filtration method and matrix-assisted laser desorption ionization-time of flight mass spectrum analysis with the SARAMIS database
    Amy Fothergill
    Emory University School of Medicine, Atlanta, Georgia, USA
    J Clin Microbiol 51:805-9. 2013
  9. doi Ammonia-oxidizing archaea and nitrite-oxidizing nitrospiras in the biofilter of a shrimp recirculating aquaculture system
    Monisha N Brown
    Department of Civil and Environmental Engineering, University of Michigan, Ann Arbor, MI 48109, USA
    FEMS Microbiol Ecol 83:17-25. 2013
  10. doi Diagnostic accuracy of urine filtration and dipstick tests for Schistosoma haematobium infection in a lightly infected population of Ghanaian schoolchildren
    Karen C Kosinski
    Department of Civil and Environmental Engineering, Tufts University, Medford, MA 02155, USA
    Acta Trop 118:123-7. 2011

Detail Information

Publications378 found, 100 shown here

  1. doi Bacterial community structure in the drinking water microbiome is governed by filtration processes
    Ameet J Pinto
    Department of Civil and Environmental Engineering, University of Michigan, USA
    Environ Sci Technol 46:8851-9. 2012
    ..Rather, in this plant, filtration by dual media rapid sand filters played a primary role in shaping the distribution system bacterial community ..
  2. ncbi Use of filter paper for the collection and analysis of human whole blood specimens
    J V Mei
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    J Nutr 131:1631S-6S. 2001
    ..These activities have created a mechanism for the validation of the filter paper blood collection device and the standardization of materials and methods for the analysis of dried blood spots...
  3. pmc 3D microfilter device for viable circulating tumor cell (CTC) enrichment from blood
    Siyang Zheng
    Department of Bioengineering, Pennsylvania State University, University Park, PA 16802, USA
    Biomed Microdevices 13:203-13. 2011
    ..supports captured cells and minimize the stress concentration on cell membrane and sustain cell viability during filtration. Viable cell capture on device was investigated with scanning electron microscopy, confocal microscopy, and ..
  4. doi A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma
    Ryan Grant
    Cellular and Molecular Immunology Research Centre, Faculty of Life Sciences, London Metropolitan University, London, UK
    J Immunol Methods 371:143-51. 2011
    ..This study describes a novel filtration method to isolate PMVs in plasma, which avoids high speed centrifugation, and to quantify them using a Becton ..
  5. pmc Air filters and air cleaners: rostrum by the American Academy of Allergy, Asthma & Immunology Indoor Allergen Committee
    James L Sublett
    Department of Pediatrics, Section of Allergy and Immunology, University of Louisville School of Medicine, 9800 Shelbyville Rd, Louisville, KY 40223, USA
    J Allergy Clin Immunol 125:32-8. 2010
    ..This rostrum serves as a resource for the allergist and other health care professionals seeking a better understanding of air filtration.
  6. doi Flexible graphene films via the filtration of water-soluble noncovalent functionalized graphene sheets
    Yuxi Xu
    Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, People s Republic of China
    J Am Chem Soc 130:5856-7. 2008
    Flexible graphene films were prepared by the filtration of water-soluble noncovalently functionalized graphene sheets with pyrenebutyrate...
  7. doi Effects of water-filtered infrared A irradiation on human fibroblasts
    Tobias Jung
    Institute of Biological Chemistry and Nutrition, University of Hohenheim, Garbenstrasse 28, 70593 Stuttgart, Germany
    Free Radic Biol Med 48:153-60. 2010
    ..Further experiments revealed that the major absorbance of infrared is due to absorption of the energy by cellular water...
  8. pmc Rapid identification of bacteria and yeasts from positive-blood-culture bottles by using a lysis-filtration method and matrix-assisted laser desorption ionization-time of flight mass spectrum analysis with the SARAMIS database
    Amy Fothergill
    Emory University School of Medicine, Atlanta, Georgia, USA
    J Clin Microbiol 51:805-9. 2013
    ..This study evaluates the performance of a novel filtration-based method for processing positive-blood-culture broth for immediate identification of microorganisms by MALDI-..
  9. doi Ammonia-oxidizing archaea and nitrite-oxidizing nitrospiras in the biofilter of a shrimp recirculating aquaculture system
    Monisha N Brown
    Department of Civil and Environmental Engineering, University of Michigan, Ann Arbor, MI 48109, USA
    FEMS Microbiol Ecol 83:17-25. 2013
    ..moscoviensis-type NOB. Water quality and biofilm attachment media played a role in the competitiveness of AOA over AOB and Nitrospira marina-over N. moscoviensis-type NOB...
  10. doi Diagnostic accuracy of urine filtration and dipstick tests for Schistosoma haematobium infection in a lightly infected population of Ghanaian schoolchildren
    Karen C Kosinski
    Department of Civil and Environmental Engineering, Tufts University, Medford, MA 02155, USA
    Acta Trop 118:123-7. 2011
    Two screening methods, reagent dipsticks for hematuria and urine filtration for Schistosoma haematobium eggs, were evaluated for their sensitivity and specificity in diagnosing infection with S...
  11. pmc Dual-source dual-energy CT with additional tin filtration: Dose and image quality evaluation in phantoms and in vivo
    Andrew N Primak
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    AJR Am J Roentgenol 195:1164-74. 2010
    The objective of this study was to investigate the effect on radiation dose and image quality of the use of additional spectral filtration for dual-energy CT using dual-source CT (DSCT).
  12. ncbi A new device for rapid isolation by size and characterization of rare circulating tumor cells
    Isabelle Desitter
    ScreenCell, 75012 Paris, France
    Anticancer Res 31:427-41. 2011
    ..Circulating tumor cells (CTCs) likely derive from clones in the primary tumor, suggesting that they can be used for all biological tests applying to the primary cells...
  13. doi Cluster randomized controlled trial of the plastic BioSand Water filter in Cambodia
    C E Stauber
    Institute of Public Health, Georgia State University, P O Box 3995, Atlanta, Georgia 30302 3995, United States
    Environ Sci Technol 46:722-8. 2012
    ..The study suggests the plastic BSF may play an important role in scaling up the distribution/implementation of the BSF, potentially improving water quality and health in the region...
  14. doi Reductions of E. coli, echovirus type 12 and bacteriophages in an intermittently operated household-scale slow sand filter
    M A Elliott
    University of North Carolina, CB 7431, Chapel Hill, NC 27599 7431, USA
    Water Res 42:2662-70. 2008
    ..3 log10 (95%) with mean reductions of only 0.5 log10 (70%). These data indicate that virus reduction by BSF may differ substantially depending upon the specific viral agent...
  15. ncbi Evaluation on the applied value of the dot immunogold filtration assay (DIGFA) for rapid detection of anti-Schistosoma japonicum antibody
    Li Yong Wen
    Research Laboratory of Molecular Immunoparasitology, Nanjing Medical University, Nanjing 210029, China
    Acta Trop 96:142-7. 2005
    The dot immunogold filtration assay (DIGFA) is a rapid technique for the detection of anti-Schistosoma japonicum antibody...
  16. pmc Effective and cheap removal of leukocytes and platelets from Plasmodium vivax infected blood
    Kanlaya Sriprawat
    Singapore Immunology Network, Biopolis, Singapore
    Malar J 8:115. 2009
    ..The aims of this study were to compare the ability of CF11 cellulose filters and the commercial filter Plasmodipur at removing leukocyte and platelet, and to investigate the retention of P. vivax IRBCs by CF11 cellulose filtration.
  17. ncbi Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin
    Thomas McDonagh
    Elixir Pharmaceuticals, One Kendall Square, Cambridge, MA 02139, USA
    Methods 36:346-50. 2005
    ..The protocol reported here is rapid and uses commercially available materials. The use of a simple microplate filtration device allows for the simultaneous processing of 96 samples, facilitating enzyme kinetic analyses and inhibition ..
  18. ncbi Indoor particles affect vascular function in the aged: an air filtration-based intervention study
    Elvira Vaclavik Bräuner
    D Institute of Public Health, Department of Environmental and Occupational Health, Øster Farimagsgade 5A, DK 1014 Copenhagen K, Denmark
    Am J Respir Crit Care Med 177:419-25. 2008
    ..Exposure to particulate matter is associated with risk of cardiovascular events, possibly through endothelial dysfunction, and indoor air may be most important...
  19. ncbi Use of hollow fiber membrane filtration for the removal of DMSO from platelet concentrates
    F Arnaud
    Naval Medical Research Center, Combat Casualty Care, Resuscitative Medicine Department, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA
    Platelets 14:131-7. 2003
    ..frozen/thawed platelet concentrates in DMSO were washed using centrifugation and compared to the HF filtration method. Platelet quality was assayed by flow cytometry, cell count, morphology and osmotic stress test...
  20. doi Equilibrium separation and filtration of particles using differential inertial focusing
    Dino Di Carlo
    BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Shriners Hospital for Children, and Harvard Medical School, Boston, Massachusetts 02114, USA
    Anal Chem 80:2204-11. 2008
    Rapid separation and filtration of particles in solution has a wide range of applications including blood cell separation, ultrasound contrast agent preparation, and purification of fermentation products...
  21. ncbi Characterisation of the biosand filter for E. coli reductions from household drinking water under controlled laboratory and field use conditions
    C E Stauber
    University of North Carolina Chapel Hill, Dept of Environmental Sciences and Engineering, 27599 Chapel Hill, NC, USA
    Water Sci Technol 54:1-7. 2006
    ..Further study is needed to determine the factors contributing to microbial reductions in BSFs and why reductions are lower than those of conventional SSFs...
  22. ncbi Performance of N95 respirators: filtration efficiency for airborne microbial and inert particles
    Y Qian
    Department of Environmental Health, University of Cincinnati, OH 45267 0056, USA
    Am Ind Hyg Assoc J 59:128-32. 1998
    ..The filtration efficiencies of unloaded N95 particulate respirators have been compared with those of dust/mist (DM) and dust/..
  23. doi Nutritional effects of culture media on mycoplasma cell size and removal by filtration
    Martha Folmsbee
    Pall Corporation, 25 Harbor Park Dr, Port Washington, NY 11050, USA
    Biologicals 38:214-7. 2010
    Careful media filtration prior to use is an important part of a mycoplasma contamination prevention program. This study was conducted to increase our knowledge of factors that influence efficient filtration of mycoplasma...
  24. doi Leaching of contaminants from untreated pine bark in a batch study: chemical analysis and ecotoxicological evaluation
    Veronica Ribé
    School of Sustainable Development of Society and Technology, Malardalen University, Box 883, SE 721 23 Västerås, Sweden
    J Hazard Mater 163:1096-100. 2009
    ..be addressed is the possibility of leaching of contaminants from the filter material, especially in the initial filtration step or during flushes of lightly contaminated water, e.g...
  25. ncbi Do blue light filters confer protection against age-related macular degeneration?
    T H Margrain
    School of Optometry and Vision Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff CF10 3NB, UK
    Prog Retin Eye Res 23:523-31. 2004
    ..Given the socio-economic impact of this disease and urgent need to identify modifiable risk factors, future work should include a large-scale clinical trial to evaluate the effect of blue blocking filters on AMD progression rates...
  26. doi Technology trends in antibody purification
    Pete Gagnon
    Bioprocessing Technology Institute, 20 Biopolis Way, 06 01 Centros, Singapore 138668 pete
    J Chromatogr A 1221:57-70. 2012
    ..methods, including precipitation, liquid-liquid extraction, and high performance tangential flow filtration. The second addresses chromatography methods. It begins with discussion of fluidized and fixed bed formats...
  27. ncbi The influence of bowtie filtration on cone-beam CT image quality
    N Mail
    Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario M5G 2M9, Canada
    Med Phys 36:22-32. 2009
    ..The implemented bowtie filter offers a significant improvement in imaging performance and is compatible with the current clinical system for image-guided radiation therapy...
  28. pmc Reduction of cholera in Bangladeshi villages by simple filtration
    Rita R Colwell
    Center of Marine Biotechnology, University of Maryland Biotechnology Institute, Baltimore, MD 21202, USA
    Proc Natl Acad Sci U S A 100:1051-5. 2003
    ..cholerae, the etiological agent of epidemic cholera, is commensal to zooplankton, notably copepods, a simple filtration procedure was developed whereby zooplankton, most phytoplankton, and particulates >20 microm were removed ..
  29. ncbi Point of use household drinking water filtration: A practical, effective solution for providing sustained access to safe drinking water in the developing world
    Mark D Sobsey
    Department of Environmental Sciences and Engineering, CB 7431, University of North Carolina, Chapel Hill, North Carolina 27599 7431, USA
    Environ Sci Technol 42:4261-7. 2008
    ....
  30. ncbi The filtration-acclimatization method for isolation of an important fraction of the not readily cultivable bacteria
    Martin W Hahn
    Institute for Limnology, Austrian Academy of Sciences, Mondseestrasse 9, Mondsee A 5310, Austria
    J Microbiol Methods 57:379-90. 2004
    We developed a novel method, the filtration-acclimatization method (FAM), which enables the isolation and cultivation of an important fraction of the bacterial diversity, which is not cultivable by standard methods...
  31. doi Application of a filtration- and isolation-by-size technique for the detection of circulating tumor cells in cutaneous melanoma
    Vincenzo de Giorgi
    Department of Critical Care Medicine and Surgery, Dermatology Unit, University of Florence, Florence, Italy
    J Invest Dermatol 130:2440-7. 2010
    ..of epithelial tumor cells (ISET) is a direct method for CTC identification in which tumor cells are collected by filtration as a result of their large size...
  32. doi Nutrient and sediment removal by stormwater biofilters: a large-scale design optimisation study
    K Bratieres
    Department of Civil Engineering, Monash University, Victoria, 3800, Australia
    Water Res 42:3930-40. 2008
    ..ericifolia. Further trials will be required to test a wider range of vegetation, and to examine performance over the longer term. Future work will also examine biofilter effectiveness for treatment of heavy metals and pathogens...
  33. ncbi A randomized controlled trial of the concrete biosand filter and its impact on diarrheal disease in Bonao, Dominican Republic
    Christine E Stauber
    Department of Environmental Science and Engineering, School of Public Health, The University of North Carolina, Chapel Hill, North Carolina 27599 7431, USA
    Am J Trop Med Hyg 80:286-93. 2009
    ..water treatment and safe storage technologies, such as chlorine disinfection, solar disinfection, and ceramic filtration, have been documented for their ability to reduce diarrheal disease and improve microbial water quality...
  34. ncbi Double-filtration plasmapheresis for resolution of corticosteroid resistant adult onset Still's disease
    Takashi Kato
    Department of Rheumatology, Kameda Medical Center, 929 Higashi Cho, Kamogawa City, Chiba, 296 8602, Japan
    Clin Rheumatol 25:579-82. 2006
    ..A diagnosis of corticosteroid resistant, severe, recurrent AOSD was made, and double-filtration plasmapheresis (DFPP) was performed immediately...
  35. ncbi Evaluation of markers to estimate volume status in hemodialysis patients: atrial natriuretic peptide, inferior vena cava diameter, blood volume changes and filtration coefficients of microvasculature
    Masatomo Yashiro
    Division of Nephrology, Kyoto City Hospital, Kyoto, Japan
    Ther Apher Dial 11:131-7. 2007
    ..vena cava diameter at quiet expiration (IVCe), blood volume change (Delta BV/TUF) during ultrafiltration and filtration coefficients of microvasculature (Lpst) - were investigated. Fifty stable hemodialysis patients were enrolled...
  36. pmc Assessing water filtration and safe storage in households with young children of HIV-positive mothers: a randomized, controlled trial in Zambia
    Rachel Peletz
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 7:e46548. 2012
    ..This population may particularly benefit from an intervention to improve water quality in the home...
  37. ncbi Removal of diclofenac potassium from wastewater using clay-micelle complex
    Rafik Karaman
    Faculty of Pharmacy, Al Quds University, Jerusalem, Palestine
    Environ Technol 33:1279-87. 2012
    ..potassium results in a high mobility of diclofenac and in its low sorption under conditions of slow sand filtration or subsoil passage. No diclofenac degradation was detected in pure water or sludge during one month...
  38. ncbi Performance of small-scale CHO perfusion cultures using an acoustic cell filtration device for cell retention: characterization of separation efficiency and impact of perfusion on product quality
    T Ryll
    Process Sciences, Genentech, Inc, 1 DNA Way, South San Francisco, California 94080 4990, USA
    Biotechnol Bioeng 69:440-9. 2000
    ..small-scale Chinese hamster ovary (CHO) suspension cultures were grown in perfusion mode using a new acoustic filtration system...
  39. doi Molecular filtration properties of the mouse expanded cumulus matrix: controlled supply of metabolites and extracellular signals to cumulus cells and the oocyte
    Kylie R Dunning
    The Robinson Institute, School of Paediatrics and Reproductive Health, The University of Adelaide, South Australia, Australia
    Biol Reprod 87:89. 2012
    ..Based on recognized filtration properties of analogous matrices, we investigated whether the cumulus matrix acts as a molecular filter by ..
  40. ncbi Continuous flow separations in microfluidic devices
    Nicole Pamme
    The University of Hull, Department of Chemistry, Cottingham Road, Hull, UK HU6 7RX
    Lab Chip 7:1644-59. 2007
    Biochemical sample mixtures are commonly separated in batch processes, such as filtration, centrifugation, chromatography or electrophoresis...
  41. doi Dot immunogold filtration assay (DIGFA) with multiple native antigens for rapid serodiagnosis of human cystic and alveolar echinococcosis
    Xiaohui Feng
    Xinjiang Hydatid Clinical Research Institute, First Teaching Hospital of Xinjiang Medical University, No 1 Liyushan RD, Urumqi 830000, Xinjiang, China
    Acta Trop 113:114-20. 2010
    A new 3-min rapid dot immunogold filtration assay (DIGFA) for serodiagnosis of human cystic and alveolar echinococcosis was developed using four native antigen preparations: crude and partially purified hydatid cyst fluid extracts from ..
  42. pmc Analysis of particulate contaminations of infusion solutions in a pediatric intensive care unit
    Thomas Jack
    Department of Pediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
    Intensive Care Med 36:707-11. 2010
    ....
  43. ncbi Use of ceramic water filtration in the prevention of diarrheal disease: a randomized controlled trial in rural South Africa and zimbabwe
    Martella Du Preez
    Natural Resources and the Environment, CSIR, Pretoria, South Africa
    Am J Trop Med Hyg 79:696-701. 2008
    ..001) and for non-bloody diarrhea was 0.17 (95% CI, 0.08-0.38; P < 0.001), indicating much lower diarrhea incidence among filter users. The results suggest that ceramic filters are effective in reducing diarrheal disease incidence...
  44. doi Glomerular albumin filtration through podocyte cell body in puromycin aminonucleoside nephrotic rat
    Akihiro Tojo
    Division of Nephrology and Endocrinology, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    Med Mol Morphol 41:92-8. 2008
    ..effaced and the number of slit membranes is reduced in nephrotic syndrome, suggesting another pathway of albumin filtration through the foot process cell body...
  45. doi Continuous scalable blood filtration device using inertial microfluidics
    Albert J Mach
    Department of Bioengineering, University of California, Los Angeles, CA, USA
    Biotechnol Bioeng 107:302-11. 2010
    ..size-based techniques that may avoid the costs or clogging issues associated with centrifugation and mechanical filtration. We present for the first time a massively parallel microfluidic device that passively separates pathogenic ..
  46. pmc Biological filtration limits carbon availability and affects downstream biofilm formation and community structure
    Chee Meng Pang
    Division of Environmental Science and Engineering, National University of Singapore, Block E2, no 04 07, 1 Engineering Drive 2, Singapore 117576
    Appl Environ Microbiol 72:5702-12. 2006
    ..g., Aquabacterium, Caulobacter, and Legionella) were preferentially selected in the BF biofilm, suggesting that carbon limitation strategies may not achieve adequate biofouling control in the long run...
  47. doi Comparative toxicity assessment of ozone and activated carbon treated sewage effluents using an in vivo test battery
    Daniel Stalter
    Goethe University Frankfurt am Main, Biological Sciences Division, Department Aquatic Ecotoxicology, Siesmayerstrasse 70, 60323 Frankfurt, Germany
    Water Res 44:2610-20. 2010
    ..after ozonation compared to conventional treatment whereas this effect was reduced following subsequent sand filtration. When ozonation was applied, a significantly increased genotoxicity was observed, detected with the comet assay ..
  48. doi The EPS characteristics of sludge in an aerobic granule membrane bioreactor
    Wang Xuan
    Tianjin Key Laboratory of Hollow Fiber Membrane Material and Membrane Process, Institute of Biological and Chemical Engineering, Tianjin Polytechnical University, Tianjin 300160, China
    Bioresour Technol 101:8046-50. 2010
    ..Furthermore, application of aerobic granule can improve sludge filtering properties and delay the process of membrane fouling, as a result of better morphological structure and lower EPS content...
  49. ncbi Investigation of bacterial removal during the filtration process in constructed wetlands
    Kirsten Sleytr
    Institute of Sanitary Engineering and Water Pollution Control, BOKU, University of Natural, Resources and Applied Life Sciences, Vienna, Muthgasse 18, A 1190 Vienna, Austria
    Sci Total Environ 380:173-80. 2007
    ..Only enterococci measured in the substrate samples of the main layer of the filter could a statistically significant difference be observed...
  50. ncbi Virus and prokaryote enumeration from planktonic aquatic environments by epifluorescence microscopy with SYBR Green I
    Anand Patel
    Marine Environmental Biology Section, University of Southern California, 3616 Trousdale Parkway, AHF 107, Los Angeles, California 90089, USA
    Nat Protoc 2:269-76. 2007
    ..The method relies on simple vacuum filtration to capture viruses on a 0...
  51. pmc An assessment of continued use and health impact of the concrete biosand filter in Bonao, Dominican Republic
    Benjamin A Aiken
    Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, NC, USA
    Am J Trop Med Hyg 85:309-17. 2011
    ..39 times the odds of reported diarrheal disease in non-BSF households. These results document high levels of sustained and effective concrete BSF use and associated improvements in water quality and health...
  52. doi Photodynamic therapy of multiple actinic keratoses: reduced pain through use of visible light plus water-filtered infrared A compared with light from light-emitting diodes
    V von Felbert
    Department of Dermatology, RWTH Aachen University, 52074 Aachen, Germany
    Br J Dermatol 163:607-15. 2010
    ..Photodynamic therapy (PDT) with methyl aminolaevulinate (MAL) is an effective treatment for multiple actinic keratoses (AKs). Pain, however, is a major side-effect...
  53. pmc Visual function in patients with yellow tinted intraocular lenses compared with vision in patients with non-tinted intraocular lenses
    K Hayashi
    Hayashi Eye Hospital, 4 7 13 Hakataekimae, Hakata Ku, Fukuoka 812, Japan
    Br J Ophthalmol 90:1019-23. 2006
    ..To compare the visual function in patients with short wavelength blue light blocking yellow tinted intraocular lenses (IOLs) with that in patients with non-tinted IOLs...
  54. ncbi Household-based ceramic water filters for the prevention of diarrhea: a randomized, controlled trial of a pilot program in Colombia
    Thomas Clasen
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Trop Med Hyg 73:790-5. 2005
    ....
  55. ncbi Prescribed burns and wildfires in Colorado: impacts of mitigation measures on indoor air particulate matter
    David E Henderson
    Department of Mechanical Engineering, University of Colorado, Boulder, CO 80309 0427, USA
    J Air Waste Manag Assoc 55:1516-26. 2005
    ..In the homes without the air cleaners, measured indoor concentrations were 58-100% of the concentrations measured outdoors...
  56. ncbi Infiltration of forest fire and residential wood smoke: an evaluation of air cleaner effectiveness
    Prabjit Barn
    School of Environmental Health, The University of British Columbia, Vancouver, British Columbia, Canada
    J Expo Sci Environ Epidemiol 18:503-11. 2008
    ..001). No significant predictors of ACE were identified. Our findings show that remaining indoors combined with use of air cleaner can effectively reduce PM(2.5) exposure during forest fires and residential wood burning...
  57. pmc Update on the glomerular filtration barrier
    George Jarad
    Renal Division, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Curr Opin Nephrol Hypertens 18:226-32. 2009
    ..is associated with abnormalities in any one layer, suggesting that each contributes to the glomerular filtration barrier (GFB). Proteinuria can also be induced in the context of a normal glomerular capillary wall...
  58. pmc Detection of circulating microparticles by flow cytometry: influence of centrifugation, filtration of buffer, and freezing
    Emily Dey-Hazra
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Vasc Health Risk Manag 6:1125-33. 2010
    ..We also analyzed the effect of filtration of buffer and long-term freezing on microparticle quantification, as well as the role of Annexin V in the ..
  59. ncbi Pyrosequencing demonstrated complex microbial communities in a membrane filtration system for a drinking water treatment plant
    Soondong Kwon
    School of Civil, Environmental and Architectural Engineering, Korea University, Seongbuk gu, Seoul 136 713, South Korea
    Microbes Environ 26:149-55. 2011
    ..and species levels, suggesting that different environmental and growth conditions were generated during membrane filtration. Moreover, signatures of potential pathogens including Legionella, Pseudomonas, Aeromonas, and Chromobacterium ..
  60. ncbi Sorption of phosphorous to Filtralite-P--the effect of different scales
    Kinga Adám
    Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, P O Box 5003, 1432 As, Norway
    Water Res 40:1143-54. 2006
    ..The surface of these precipitation particles was identified by X-ray diffraction and SEM method as CaCO3 and precipitated Ca- and Mg-phosphates...
  61. pmc Cigarette filter ventilation is a defective design because of misleading taste, bigger puffs, and blocked vents
    L T Kozlowski
    Department of Biobehavioral Health, The Pennsylvania State University, Pennsylvania 16802, USA
    Tob Control 11:I40-50. 2002
    ....
  62. ncbi Clinical effectiveness of leukocyte filtration during cardiopulmonary bypass in patients with chronic obstructive pulmonary disease
    Theodoros E Karaiskos
    Third Department of Cardiac Surgery, Onassis Cardiac Surgery Center, Athens, Greece
    Ann Thorac Surg 78:1339-44. 2004
    We tested the hypothesis that leukocyte filtration during pulmonary reperfusion preserves pulmonary function and results in improved oxygenation after cardiopulmonary bypass (CPB) in patients with chronic obstructive pulmonary disease (..
  63. ncbi Pathogen filtration, heterogeneity, and the potable reuse of wastewater
    J A Redman
    Department of Chemical and Biochemical Engineering and Material Science, University of California, Irvine, California 92697, USA
    Environ Sci Technol 35:1798-805. 2001
    b>Filtration is commonly employed in water and wastewater treatment to remove particles and reduce the concentration of microbial pathogens...
  64. ncbi Substrates for phosphorus removal-potential benefits for on-site wastewater treatment?
    Lena Johansson Westholm
    Department of Public Technology, Malardalen University, P O Box 883, SE 721 23 Västerås, Sweden
    Water Res 40:23-36. 2006
    ..The problems of normalisation of data are discussed, as well as the substrates potential benefits for on-site wastewater treatment...
  65. ncbi Effect of sampling time on the culturability of airborne fungi and bacteria sampled by filtration
    Kate T H Durand
    University of Washington, School of Public Health and Community Medicine, Department of Environmental Health, Seattle 98195, USA
    Ann Occup Hyg 46:113-8. 2002
    Air sampling of bioaerosols by filtration may be preferable for many epidemiological studies because the methods can be used to collect personal samples for a full work-shift...
  66. ncbi Biomass development in slow sand filters
    L C Campos
    Department of Civil and Environmental Engineering, Imperial College of Science, Technology and Medicine, London, UK
    Water Res 36:4543-51. 2002
    ....
  67. ncbi Plasmapheresis for severe lipemia: comparison of serum-lipid clearance rates for the plasma-exchange and double-filtration variants
    Jiann Horng Yeh
    Department of Neurology, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan
    J Clin Apher 18:32-6. 2003
    ..patients who had not responded to previous therapies were selected for either the plasma-exchange (PE) or double-filtration (DF) treatment variants...
  68. doi Development and application of a differential method for reliable metabolome analysis in Escherichia coli
    Hilal Taymaz-Nikerel
    Department of Biotechnology, Delft University of Technology, BC Delft, The Netherlands
    Anal Biochem 386:9-19. 2009
    ..Different methods for sampling of culture filtrate were examined, and it was found that direct filtration without cooling of the sample was the most appropriate...
  69. ncbi A multi-well filtration assay for quantitation of inositol phosphates in biological samples
    M Chengalvala
    Women s Health Research Institute, Wyeth Ayerst Research, Radnor, PA 19087, USA
    J Biochem Biophys Methods 38:163-70. 1999
    ..Cell lysates containing labeled IPs were applied in 96-well plates fitted with filtration discs containing regenerated Dowex AGI-X8 resin...
  70. ncbi Contrast is enhanced by yellow lenses because of selective reduction of short-wavelength light
    J S Wolffsohn
    Clinic Research Unit, Victorian College of Optometry, University of Melbourne, Australia
    Optom Vis Sci 77:73-81. 2000
    ..Although many studies have shown a subjective preference for yellow lenses, there has been little success in determining the clinical nature of this benefit...
  71. pmc Cigarettes with defective filters marketed for 40 years: what Philip Morris never told smokers
    J L Pauly
    Department of Immunology, Roswell Park Cancer Institute, New York State Department of Health, Buffalo, New York 14263, USA
    Tob Control 11:I51-61. 2002
    ..Cigarettes with filters that release cellulose acetate or carbon particles during normal smoking conditions are defective...
  72. pmc Rate of decline in serum PFOA concentrations after granular activated carbon filtration at two public water systems in Ohio and West Virginia
    Scott M Bartell
    Program in Public Health, University of California, Irvine, California 92697 1250, USA
    Environ Health Perspect 118:222-8. 2010
    ..Two highly contaminated water districts began granular activated carbon filtration in 2007.
  73. doi Double filtration plasmapheresis in antibody-incompatible kidney transplantation
    Rob Higgins
    Transplant Unit, University Hospitals Coventry and Warwickshire, Coventry, UK
    Ther Apher Dial 14:392-9. 2010
    Double filtration plasmapheresis (DFPP) was used in preference to plasma exchange in our program of antibody-incompatible transplantation, to treat higher volumes of plasma...
  74. ncbi Local drinking water filters reduce diarrheal disease in Cambodia: a randomized, controlled trial of the ceramic water purifier
    Joe Brown
    University of Alabama, Department of Biological Sciences, Tuscaloosa, AL 35487 0229, USA
    Am J Trop Med Hyg 79:394-400. 2008
    ..51 (95% confidence interval [CI]: 0.41-0.63); CWP-Fe: 0.58 (95% CI: 0.47-0.71), an effect that was observed in all age groups and both sexes after controlling for clustering within households and within individuals over time...
  75. ncbi An in vitro comparison of microleakage between Resilon and gutta-percha with a fluid filtration model
    Jaron R Wedding
    Department of Endodontics, Indiana University School of Dentistry, Indianapolis, Indiana 46202, USA
    J Endod 33:1447-9. 2007
    ..compared microleakage of teeth obturated with gutta-percha and teeth obturated with Resilon by using a fluid filtration model. Forty-six human, single-rooted, mandibular premolars were studied...
  76. pmc Filter ventilation and nicotine content of tobacco in cigarettes from Canada, the United Kingdom, and the United States
    L T Kozlowski
    Department of Biobehavioral Health, Penn State University, University Park, Pennsylvania 16802, USA
    Tob Control 7:369-75. 1998
    ..The purpose was to determine filter ventilation and the nicotine content of tobacco and their contribution to machine-smoked yields of cigarettes from the United States, Canada, and the United Kingdom...
  77. ncbi Considerations for improving the accuracy of exposure to disinfection by-products by ingestion in epidemiologic studies
    Howard S Weinberg
    Department of Environmental Sciences and Engineering, University of North Carolina, School of Public Health, Rosenau Hall, South Columbia St, Chapel Hill, NC 27599 7431, USA
    Sci Total Environ 354:35-42. 2006
    ..These factors should be taken into consideration in DBP exposure characterization for epidemiologic studies...
  78. ncbi Hydrodynamic filtration for on-chip particle concentration and classification utilizing microfluidics
    Masumi Yamada
    Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8656, Japan
    Lab Chip 5:1233-9. 2005
    ..method for continuous concentration and classification of particles in microfluidic devices, named hydrodynamic filtration. When a particle is flowing in a microchannel, the center position of the particle cannot be present in a ..
  79. pmc Control of asthma triggers in indoor air with air cleaners: a modeling analysis
    Theodore A Myatt
    Environmental Health and Engineering, Inc, 117 Fourth Avenue, Needham, MA 02494 2725, USA
    Environ Health 7:43. 2008
    ..The potential exposure benefits of whole house high efficiency in-duct air cleaners for sensitive subpopulations have yet to be evaluated...
  80. doi AcrySof Natural filter decreases blue light-induced apoptosis in human retinal pigment epithelium
    Kourous A Rezai
    Department of Ophthalmology, Rush University Medical Center, Chicago, IL, USA
    Graefes Arch Clin Exp Ophthalmol 246:671-6. 2008
    ..The effect of AcrySof filter (UV light-filtering chromophore; Alcon) and AcrySof Natural filter (UV- and blue light-filtering chromophores) on blue light-induced apoptosis in human retinal pigment epithelial (RPE) cells was evaluated...
  81. ncbi Understanding the size and character of fouling-causing substances from effluent organic matter (EfOM) in low-pressure membrane filtration
    Claudia N Laabs
    Department of Water Quality Control, Technical University Berlin, Sekr KF 4, Strasse des 17 Juni 135, 10623 Berlin, Germany
    Environ Sci Technol 40:4495-9. 2006
    ..This time corresponds to the filtration of a cumulative volume of 110 L/m2...
  82. ncbi The use and performance of BioSand filters in the Artibonite Valley of Haiti: a field study of 107 households
    W F Duke
    Water and Watershed Research Program, Dept of Biology, University of Victoria, Victoria, BC, Canada
    Rural Remote Health 6:570. 2006
    ..Approximately one billion people world-wide lack access to adequate amounts of safe water. Most are in developing countries, especially in rapidly expanding urban fringes, poor rural areas, and indigenous communities...
  83. doi Use of hollow fiber tangential flow filtration for the recovery and concentration of HIV virus-like particles produced in insect cells
    Alejandro Negrete
    Biotechnology Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States Electronic address
    J Virol Methods 195:240-6. 2014
    ..In this study a two-step tangential flow filtration (TFF) process using hollow fibers was developed for the clarification and concentration of HIV gag-VLPs...
  84. ncbi Assessment of biosand filter performance in rural communities in southern coastal Nicaragua: an evaluation of 199 households
    M M Fiore
    University of Michigan, Ann Arbor, Michigan, USA
    Rural Remote Health 10:1483. 2010
    ..Approximately 600 filters had been installed in this area over the preceding 2 years by local workers supported by US and Canadian NGOs...
  85. doi Collimator with filtration compensator: clinical adaptation to meet European Union recommendation 4F on radiological protection for dental radiography
    M Alcaraz
    Department of Radiology and Physical Medicine, Faculty of Medicine Dentistry, University of Murcia, Murcia, Spain
    Dentomaxillofac Radiol 38:413-20. 2009
    Our aim was to develop a compensated filtration collimator for use in paediatric patients undergoing cephalometric radiography that reduces the radiation dose administered and fulfils recommendation 4F of the European guidelines on ..
  86. ncbi Interactions of aqueous NOM with nanoscale TiO2: implications for ceramic membrane filtration-ozonation hybrid process
    Jeonghwan Kim
    Department of Civil and Environmental Engineering, Michigan State University, East Lansing, Michigan 48823, USA
    Environ Sci Technol 43:5488-94. 2009
    ..Non-XDLVO interactions such as intermolecular bridging by calcium were hypothesized to be responsible for the observed adsorption behavior. Adsorption data proved to be highly predictive of the permeate flux performance...
  87. ncbi Discriminating and assessing adsorption and biodegradation removal mechanisms during granular activated carbon filtration of microcystin toxins
    Haixiang Wang
    School of Chemical Engineering, The University of Adelaide, Adelaide, SA 5005, Australia
    Water Res 41:4262-70. 2007
    ..Granular activated carbon (GAC) filtration has been shown to be effective in removing microcystin from water using both adsorption and biodegradation ..
  88. pmc The Sonoma water evaluation trial: a randomized drinking water intervention trial to reduce gastrointestinal illness in older adults
    John M Colford
    School of Public Health, University of California, 50 University Hall, MC 7360, Berkeley, CA 94720 7360, USA
    Am J Public Health 99:1988-95. 2009
    ..the relative rate of highly credible gastrointestinal illness (HCGI) per year associated with active versus sham household water filtration devices among older adults in a community receiving tap water meeting current US standards.
  89. ncbi Effects of sublethal Zn++ and Cd ++ concentrations on filtration rate, absorption efficiency and scope for growth in Donax trunculus (Bivalvia; Donacidae)
    Lya Neuberger-Cywiak
    Department of Biology of Organisms, Simon Bolivar University, Baruta A P 89000, Caracas 1080, Venezuela
    Bull Environ Contam Toxicol 79:622-7. 2007
    Physiological parameters (filtration rate measured as clearance rate; absorption efficiency measured as Conover index) and energy balance [scope for growth (SFG)] where determined under Zn++ (essential metal) and Cd++ (nonessential metal) ..
  90. doi Rapid analysis of Gram-positive bacteria in water via membrane filtration coupled with nanoprobe-based MALDI-MS
    Shuping Li
    Centre for Advanced Water Technology, Public Utilities Board, 82 Toh Guan Road East, Waterhub, C4 03, Singapore 608576, Singapore
    Anal Bioanal Chem 397:2465-76. 2010
    ..It involves a combination of membrane filtration (MF) and vancomycin-conjugated magnetite nanoparticles (VNPs) to selectively separate and concentrate Gram-..
  91. ncbi Demand-based water options for arsenic mitigation: an experience from rural Bangladesh
    B A Hoque
    Environment and Population Research Center, Lalmatia, Dhaka, Bangladesh
    Public Health 118:70-7. 2004
    ..For arsenic-affected areas, it is recommended that a cluster-based piped water system be given proper consideration when selecting appropriate water options rather than household-based options or the development of new low-cost options...
  92. ncbi Coupled plasma filtration adsorption
    Rinaldo Bellomo
    Department of Intensive Care, Austin and Repatriation Medical Centre, Studley Rd, 3084, Heidelberg, Victoria, Melbourne, Australia
    Intensive Care Med 29:1222-8. 2003
    ..It might be possible to treat plasma in such a way that the injurious effect of mediators can be attenuated...
  93. pmc One-step purification of nucleic acid for gene expression analysis via Immiscible Filtration Assisted by Surface Tension (IFAST)
    Scott M Berry
    Department of Biomedical Engineering, University of Wisconsin Madison, 1111 Highland Ave, Rm 6009, Madison, WI 53705, USA
    Lab Chip 11:1747-53. 2011
    ..mechanism, replacing all washing steps with a single traverse of an immiscible fluid barrier, termed Immiscible Filtration Assisted by Surface Tension (IFAST)...
  94. pmc Comparison of lysis filtration and an automated blood culture system (BACTEC) for detection, quantification, and identification of odontogenic bacteremia in children
    Victoria S Lucas
    Department of Oral Medicine, The Eastman Dental Institute for Oral Healthcare Sciences, University College London, London WC1X 8LD, United Kingdom
    J Clin Microbiol 40:3416-20. 2002
    Lysis filtration (LyF) was compared with BACTEC PAEDS PLUS in estimating the prevalence of, and sensitivity for, detection of odontogenic bacteremia...
  95. pmc Field assessment of a novel household-based water filtration device: a randomised, placebo-controlled trial in the Democratic Republic of Congo
    Sophie Boisson
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 5:e12613. 2010
    ..However, current methods of treating water at home have certain shortcomings, and there is evidence of bias in the reported health impact of the intervention in open trial designs...
  96. doi Epidemiological study of air filtration systems for preventing PRRSV infection in large sow herds
    Carmen Alonso
    Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    Prev Vet Med 112:109-17. 2013
    ..Aerosol transmission among herds is a major concern in pig dense regions and filtration of incoming air, in combination with standard biosecurity procedures, has been demonstrated to prevent ..
  97. ncbi Test methods for evaluating the filtration and particulate emission characteristics of vacuum cleaners
    K Willeke
    Department of Environmental Health, University of Cincinnati, OH 45267 0056, USA
    AIHAJ 62:313-21. 2001
    The overall filtration efficiency of a vacuum cleaner traditionally has been tested by placing the vacuum cleaner in a test chamber and measuring aerosol concentrations at the chamber inlet and outlet...
  98. doi Point-of-use membrane filtration and hyperchlorination to prevent patient exposure to rapidly growing mycobacteria in the potable water supply of a skilled nursing facility
    Margaret M Williams
    National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Infect Control Hosp Epidemiol 32:837-44. 2011
    ..An investigation ruled out bronchoscopy procedures, specimen collection, and scope reprocessing at the hospitals as sources of transmission...
  99. ncbi Intermittent high-pressure sequential bioreactor (IHPSB) with integration of sand filtration system for synthetic wastewater treatment
    Yang Min Liang
    Department of Water Resources and Environmental Engineering, TamKang University 151 Ying Chuan Road, Tamsui district 25137, New Taipei City, Taiwan
    Environ Technol 33:937-42. 2012
    A pressurized activated sludge reactor with a sand layer installed at the bottom of the reactor for filtration purposes was employed for treating synthetic organic wastewater...
  100. pmc A randomized controlled trial of the plastic-housing BioSand filter and its impact on diarrheal disease in Copan, Honduras
    Anna M Fabiszewski de Aceituno
    Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA
    Am J Trop Med Hyg 86:913-21. 2012
    ..Households with a BSF had significantly better drinking water quality regardless of water source or season...
  101. ncbi Measurement of TFF3 mRNA in aspirates from thyroid nodules using mesh filtration: the first clinical trial in 130 cases
    Hiroya Yamada
    Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita 565 0871, Japan
    Endocr J 59:621-30. 2012
    ..this study, we established a novel method to separate thyroid tumor cells from blood cells efficiently with mesh filtration. The expression level of trefoil factor 3 (TFF3) mRNA was estimated using LGALS3 mRNA as an internal control (T/..

Research Grants75

  1. Angiotensin Adrenergic Interactions in the Kidney
    Roland C Blantz; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Project Summary/Abstract In the normal kidney glomerular filtration rate (GFR) is accompanied by parallel changes in Na reabsorption (TNa)...
  2. New insights in mechanisms of renal injury
    Balakuntalam S Kasinath; Fiscal Year: 2013
    ..Glomerular filtration rate (GFR) and albuminuria will be measured...
  3. Role of Endocytosis and Vesicular Trafficking in Podocyte Health and Filter Integ
    Puneet Garg; Fiscal Year: 2012
    ..NPHS2 that result in proteinuric renal diseases have placed the emphasis on podocyte as primary component of the filtration barrier and important for normal glomerular function...
  4. Durable Visible Light-activated Antivral Coatings for Fabrics Used for Personal P
    JOSEF STEPHAN SCHNEIDER; Fiscal Year: 2011
    ..3) Demonstrate that the optimized antiviral coatings on the filtration medium do not interfere with the ease of use, fit and comfort characteristics of the mask/respirator...
  5. Mechanisms of ethanol-induced neurodevelopmental effects
    Marina Guizzetti; Fiscal Year: 2011
    ..The effect of ethanol on the composition of astrocyte-produced lipoproteins separated by gel filtration, and their role on cholesterol efflux from neurons will be analyzed...
  6. Suppression of Ocular Scarring - Controlled Delivery of an ALK-5 Inhibitor
    Hiroshi Nakamura; Fiscal Year: 2013
    ..Glaucoma filtration surgery (GFS) is a procedure frequently performed in glaucoma patients and has been reported to produce the ..
  7. A multicenter clinical trial of allopurinol to prevent GFR loss in T1D
    S MICHAEL MAUER; Fiscal Year: 2012
    ..To study whether uric acid lowering can reduce glomerular filtration rate (GFR) loss in T1D, we have established the PERL (Preventing Early Renal Function Loss in Diabetes) ..
  8. Oxidative Stress in Chronic Kidney Disease
    Talat Alp Ikizler; Fiscal Year: 2012
    ABSTRACT Chronic kidney disease (CKD), defined as a persistently reduced glomerular filtration rate (GFR), is an important public health problem affecting more than 26 million Americans...
  9. Markers of Renal Damage in Renovascular Hypertension
    Juan C Romero; Fiscal Year: 2011
    ..are due to the lack of important information about the changes in intrarenal hemodynamics, glomerular filtration rate and proximal and distal tubular function in the stenotic kidney (ST-KD) as well as in the contralateral ..
  10. Effect of Ultrafiltration on Clinical Outcomes and Health-related Quality of Life
    KELLY VICTORIA LIANG; Fiscal Year: 2013
    ..prospective randomized study of hospitalized HF patients with underlying renal dysfunction (estimated glomerular filtration rate (GFR) 15-59 mL/min) treated with either protocolized treatment with early UF after failing medical therapy ..
  11. Identifying Key Structural Elements in the Activation of the Arp2/3 Complex
    Patricia A Khuu; Fiscal Year: 2013
    ..Mutant complexes will be purified through GST-VCA affinity, ion exchange, and gel filtration chromatography...
  12. Central Biochemistry Laboratory of the CKiD Consortium
    George J Schwartz; Fiscal Year: 2013
    ..with protocols, kits, reagents, supplies, and transportation required for performing iohexol-based glomerular filtration rate (GFR) studies and collecting blood and urine for analysis at URMC and other laboratories...
  13. The role of SIRT1/FOXO4 pathway in podocyte apoptosis of diabetes mellitus
    PETER YENLUNG CHUANG; Fiscal Year: 2013
    ..Podocytes are specialized, terminally differentiated cells that maintain the kidney's filtration barrier...
  14. Design of a Multicenter Clinical Trial of Allopurinol to Prevent GFR Loss in T1D
    S MICHAEL MAUER; Fiscal Year: 2011
    ..To study whether uric acid lowering can reduce glomerular filtration rate (GFR) loss in T1D, we have established a consortium that includes investigators from the Joslin Diabetes ..
  15. Contribution of Gstm1 to the severity of hypertension and chronic kidney disease
    Thu H Le; Fiscal Year: 2013
    ..We found that the hazard ratios (HR) for the time to glomerular filtration rate (GFR) event, dialysis or death in those with two or one null alleles relative to those with two active ..
  16. Homocysteine and Angiotensin II in Renovascular Remodeling
    Utpal Sen; Fiscal Year: 2013
    ..Renal function will be determined by measuring glomerular filtration rate (GFR)...
  17. Endogenous Cardiac Glycosides in AASK
    Brad C Astor; Fiscal Year: 2010
    ..of 255 AASK participants and coorelate these measures with markers of kidney function (estimated glomerular filtration rate, albuminuria), daytime and nighttime blood pressure, NT-proBNP, cardiac troponins I, and left ventricular ..
  18. Conservative Versus Dialytic Management in Stage V Chronic Kidney Disease
    GLENN MATTHEW CHERTOW; Fiscal Year: 2010
    ..randomizing elderly (age >70 years) subjects with stage V chronic kidney disease (CKD) (estimated glomerular filtration rate (eGFR) 9 to <15 mL/min/1...
  19. Mesonephric Model of Podocyte Injury and Regeneration
    Weibin Zhou; Fiscal Year: 2012
    ..by proteinuria, hypoalbuminemia, edema, and hyperlipidemia, due to the disruption of renal glomerular filtration barrier (GFB) function...
  20. FEASIBILITY OF REPAIRING GBM DEFECTS IN VIVO
    Jeffrey H Miner; Fiscal Year: 2012
    ..membrane (GBM) is a specialized extracellular matrix and a crucial component of the kidney's glomerular filtration barrier (GFB) between the vasculature and the urinary space...
  21. Early Life Stress &Chronic Control of Blood Pressure
    Analia Loria; Fiscal Year: 2013
    ..Adult maternally separated (MS) rats show lower glomerular filtration rate under baseline conditions compared to control, un-separated littermates, with no difference in blood ..
  22. Early Life Stress &Chronic Control of Blood Pressure
    Analia Loria; Fiscal Year: 2013
    ..Adult maternally separated (MS) rats show lower glomerular filtration rate under baseline conditions compared to control, un-separated littermates, with no difference in blood ..
  23. PERL: A multicenter clinical trial of allopurinol to prevent GFR loss in T1D
    S MICHAEL MAUER; Fiscal Year: 2013
    ..To study whether uric acid lowering can reduce glomerular filtration rate (GFR) loss in T1D, we have established the PERL (Preventing Early Renal Function Loss in Diabetes) ..
  24. BIOCHEMISTRY AND PHARMACOLOGY OF THE MACULAR CAROTENOIDS
    PAUL STEVEN BERNSTEIN; Fiscal Year: 2013
    ..diseases of the retina including age-related macular degeneration (AMD) by multiple mechanisms including filtration of phototoxic blue light and antioxidant quenching of reactive oxygen species...
  25. L-arginine supplement for the prevention of calcineurin inhibitor nephrotoxicity
    W Ray Kim; Fiscal Year: 2011
    ..Additionally, the effects of oral L-arginine on glomerular filtration rate, cardiac output, systemic vascular resistance, endothelial function, plasma arginine level and urinary ..
  26. Phenotypes of diabetic kidney disease and the relationship to retinal pathology
    Amy Mottl; Fiscal Year: 2013
    ..The predictive ability of retinopathy severity for albuminuria progression and decline in glomerular filtration rate (GFR) over four years will be analyzed...
  27. Integrated Cardio-Renal Risk Prediction Models in Type 1 Diabetes
    Marian J Rewers; Fiscal Year: 2010
    ..function estimated from serum cystatin C have changed this paradigm by demonstrating that decline in glomerular filtration may begin in the absence of microalbuminuria or continue despite remission of microalbuminuria...
  28. NITRIC OXIDE AND OXYGENATION IN DIABETIC KIDNEYS
    NILS AXEL FREDRIK PALM; Fiscal Year: 2010
    ..we will develop and validate protocol for noninvasive measurements of renal blood, oxygen usage and glomerular filtration rate by magnetic resonance...
  29. System for Decontaminating Well Water for Drinking
    GIRISH SRINIVAS; Fiscal Year: 2010
    ..When water purification beyond filtration and softening is needed due to groundwater contamination, a small, point-of-use water purification device that ..
  30. Insulin Resistance in Chronic Kidney Disease
    Ian H De Boer; Fiscal Year: 2013
    ..Moderate-severe CKD (stage 3-4, defined by glomerular filtration rate 15-59 mL/min/1...
  31. Novel Models of Diabetic Nephropathy
    Moshe Levi; Fiscal Year: 2010
    ..Phenotyping: In these mice we will determine a) the manifestation of diabetic nephropathy, including glomerular filtration rate, glomerulosclerosis, tubulointerstitial fibrosis, and proteinuria and b) the cellular and biochemical ..
  32. The ISCHEMIA-CKD Trial-CCC-Lead Application
    Sripal Bangalore; Fiscal Year: 2013
    ..heart disease (SIHD) patients with advanced chronic kidney disease (CKD) [defined as estimated glomerular filtration rate (eGFR) <30 mL/min/1.73m2) or on dialysis] and moderate-severe ischemia...
  33. Alpha actinin 4: its functions and regulation
    Hung Ying Kao; Fiscal Year: 2013
    ..interdigitating into the unique foot processes and slit diaphragms which function as key components of the filtration barrier...
  34. Measurement of Renal Viscoelastic Properties with Ultrasound
    MATTHEW WILLIAM URBAN; Fiscal Year: 2013
    ..Noninvasive indicators of kidney disease including levels of serum creatinine, glomerular filtration rate, and classical medical imaging can provide certain insights into kidney disease state...
  35. Mesonephric Model of Podocyte Injury and Regeneration
    Weibin Zhou; Fiscal Year: 2013
    ..by proteinuria, hypoalbuminemia, edema, and hyperlipidemia, due to the disruption of renal glomerular filtration barrier (GFB) function...
  36. Randomized trial of vitamin D and omega-3 fatty acids for diabetic kidney disease
    Ian H De Boer; Fiscal Year: 2013
    ..to test whether vitamin D3 and/or omega-3 fatty acids prevent progression of albuminuria and loss of glomerular filtration rate, two complementary manifestations of DKD, over 4 years of treatment...
  37. Sorbents for Toxic-Metal Removal in Pharmaceutical Development and Manufacture
    GIRISH SRINIVAS; Fiscal Year: 2013
    ..bulky coordination complexes, cluster compounds and nanoparticles that are not easily removed by conventional filtration, centrifugation or metal scavengers...
  38. Molecular Mechanisms of Albumin Trafficking in Podocytes
    Judith T Blaine; Fiscal Year: 2013
    ..In normal subjects, resistance to albumin excretion in the urine is mediated by an intact glomerular filtration barrier which is comprised of glomerular endothelial cells, the glomerular basement membrane, podocyte foot ..
  39. STUDIES ON THE STRUCTURE OF BASEMENT MEMBRANES
    BILLY GERALD HUDSON; Fiscal Year: 2013
    ..architecture and functioning of the collagen IV networks, which are the principal components of the renal filtration barrier...
  40. Effectiveness of Immediate vs. Delayed Use of Metformin in New-Onset T2 Diabetes
    JOE VANDIVER SELBY; Fiscal Year: 2010
    ..complications (new onset diabetic retinopathy, microalbuminuria, or rate of decline in estimated glomerular filtration rate). We recognize the risks of confounding inherent in observational approaches...
  41. Gestational Stress and Impaired Iron Homeostasis in the Young Infant
    Christopher L Coe; Fiscal Year: 2013
    ..When infants are 8 months of age, measures of glomerular filtration rate and renal sympathetic input will be obtained...
  42. RENALASE DEFICIENCY AND CARDIOVASCULAR COMPLICATIONS OF CHRONIC KIDNEY DISEASE
    Gary V Desir; Fiscal Year: 2010
    ..Blood renalase levels are inversely correlated with glomerular filtration rate (GFR) and markedly reduced in patients with advanced CKD, and end stage kidney disease (ESRD)...
  43. Predicting the burden of renal disease among liver transplant recipients
    Pratima Sharma; Fiscal Year: 2013
    ..provided by applicant): Post-liver transplant chronic renal failure (CRF), defined as estimated glomerular filtration rate (eGFR) <30 ml/min or end-stage renal disease (ESRD), is one of the major post-transplant co-morbidities ..
  44. Structural studies of PKR regulation by viral non-coding RNA
    GRAEME LESLIE CONN; Fiscal Year: 2013
    ..inhibition functional assays, and qualitative or quantitative measurement of PKR-RNA binding by gel filtration chromatography or isothermal titration calorimetry, respectively...
  45. EPITHELIAL OXALATE AND CITRATE TRANSPORT
    DAVID BRUCE MOUNT; Fiscal Year: 2011
    Oxalate is excreted in the urine via a combination of both glomerular filtration and proximal tubular secretion...
  46. Ameliorating Sickle Nephropathy and Pulmonary Hypertension
    Punam Malik; Fiscal Year: 2013
    ..Children, and even infants with SCA develop a urine concentrating defect (UCD), increased glomerular filtration rate (GFR), supranormal proximal tubular function and impaired ability to excrete potassium...
  47. The Aging Kidney in HIV-Infection: biomarkers for early detection of injury
    Michael G Shlipak; Fiscal Year: 2013
    ..Kidney function estimates based on creatinine are unreliable until the glomerular filtration rate (GFR) has been substantially reduced;by this time, kidney disease is established and the primary prevention ..
  48. Disparities in Progression to Renal Replacement Therapy
    Stephen F Derose; Fiscal Year: 2011
    ..to ESRD and death from different starting points defined by kidney function, as measured by estimated glomerular filtration rate (eGFR). We will also examine the rate of change in kidney function...
  49. Biomechanics of Blood Stream Infections
    John G Younger; Fiscal Year: 2012
    ..questions: When encountering a capillary, can a biofilm-derived aggregate deform sufficiently to escape filtration? When traveling in the bloodstream, will debris fracture into constituent bacteria or remain as multicellular ..
  50. Cytokine based murine focal glomerulosclerosis model a prelude to novel therapy
    Virginia J Savin; Fiscal Year: 2013
    ..bind to the FSGS factor and/or CLC-1 and prevent its effect on the glomerulus, agents that may protect the filtration barrier through action on the glomerulus itself and additional pharmacological agents that have shown promise as ..
  51. Disordered Mineral Metabolism in the CKiD Children: Role of FGF-23
    Anthony A Portale; Fiscal Year: 2013
    ..FGF-23 levels increase progressively as glomerular filtration rate (GFR) declines in adults with CKD, before the development of hyperphosphatemia, and the increased FGF-23 ..
  52. TGF-beta1 and Mitochondrial Dysfunction in LPS-Induced Renal Failure
    L Jay Stallons; Fiscal Year: 2013
    ..Glomerular filtration was normal at 18 h but decreased (i.e. elevated serum creatinine) 42 h after LPS injection...
  53. New Thoughts on Parietal Epithelial Cells
    Stuart Shankland; Fiscal Year: 2010
    ..basement membrane form a second glomerular permeability barrier, distinct from the conventional glomerular filtration barrier (which comprises the endothelium, GBM, podocytes)...
  54. ISCHEMIA-CKD SDCC
    SEAN M O'BRIEN; Fiscal Year: 2013
    ..heart disease (SIHD) patients with advanced chronic kidney disease (CKD) [defined as estimated glomerular filtration rate (eGFR) <30 mL/min/1.73m2) or on dialysis] and moderate-severe ischemia...
  55. Subclinical Renal Artery Atherosclerosis, Kidney Function and Hypertension
    Matthew A Allison; Fiscal Year: 2011
    ..to determine if: 1) Renal artery calcium (RAC) is associated with kidney function, as measured by a) glomerular filtration rate, b) cystatin-C and 3) urine albumin;2) Both baseline and prospective changes in RAC are significantly ..
  56. Pathophysiology of Heart Failure with a Normal Ejection Fraction in the Elderly
    Mathew S Maurer; Fiscal Year: 2010
    ..of these subjects (76%) have a true anemia by blood volume analysis, which is associated with the glornerular filtration rate, suggesting that inadequate production of erythropoeitin may be a mechanism for their anemia...
  57. Ambulatory Case and Preventable Hospitalizations in Diabetic Kidney Disease
    Chin Lin Tseng; Fiscal Year: 2013
    ..diabetes, we will establish a study cohort of patients in FY 2000-2006 with CKD, stage 2-4 (estimated glomerular filtration rate (eGFR) of 15-90 ml/min/1.73m2) and follow them for PQIs through FY 2009...
  58. Characterizing the effects of Mouse Maturation on the Expression of Acute Renal F
    Richard A Zager; Fiscal Year: 2010
    ..4 month old mice subjected to the same injury protocols sustain severe tubular necrosis, cast formation, and filtration failure...
  59. Urinary peptide excretion and onset of puberty
    Stephen Barnes; Fiscal Year: 2009
    ..Although urine contains some intact proteins, filtration by kidney glomeruli results in the bulk of detectable peptides being below 20 kDa...
  60. Racial Differences in Phosphorus Metabolism in Health and in Kidney Disease
    ORLANDO M GUTIERREZ; Fiscal Year: 2012
    ..that Blacks with CKD have a higher prevalence of hyperphosphatemia than Whites at all levels of glomerular filtration rate despite higher PTH levels, suggesting that Blacks have impaired Pi excreting capacity...
  61. Trajectories of Kidney Dysfunction in Older Adults with Chronic Kidney Disease
    CHRISTOPHER BARRETT BOWLING; Fiscal Year: 2013
    ..In the VA population, the prevalence of chronic kidney disease (CKD), defined as an estimated glomerular filtration rate (eGFR) <60 ml/min/1...
  62. Molecular pathogenesis of anti-glomerular basement membrane nephritis
    Dorin Bogdan Borza; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): The glomerular basement membrane (GBM) is an essential part of the blood filtration barrier and the primary site of injury in aggressive forms of glomerulonephritis mediated by anti-GBM antibodies...
  63. Clinical Trial of the FAST Real-Time GFR System
    Bruce A Molitoris; Fiscal Year: 2011
    ..fluorescent device in humans and commercialize this device for rapid detection and quantification of glomerular filtration rate (GFR) in patients with acute kidney injury (AKI) and/or chronic kidney disease (CKD)...
  64. Circulatory Dysfunction in Chronic Fatigue Syndrome
    Julian Stewart; Fiscal Year: 2004
    ..redistributed peripherally and redistribution is enhanced during orthostasis producing increased microvascular filtration and dependent edema...
  65. INFERIOR VENA CAVA FILTRATION WITH A REMOVABLE DEVICE
    Elvira Lang; Fiscal Year: 1999
    ..Costs of permanent filters range between $600-$1400. An efficient and practical removable filter system could represent an annual market opportunity of 60- 140 million dollars in the United States alone. ..
  66. Renal Control of Blood Pressure in Early Diabetes
    Michael Brands; Fiscal Year: 2007
    ..Our L-NAME, ACh, and glomerular filtration rate (GFR) data support this, but to better implicate NO and define the site(s) for its control of renal ..
  67. PHYSIOLOGIC RESPONSE TO THERMAL INJURY
    EDWARD PAVLIN; Fiscal Year: 1990
    ..g. increases in basal metabolic rate, cardiac output and glomerular filtration rate. Physiologic responses to thermal injury result in altered requirements for many different types of drugs...
  68. Solar Water Disinfection: Randomized Intervention Trial
    JOHN COLFORD; Fiscal Year: 2006
    ..gastroenteritis remains a major infrastructural and public health problem particularly, as effective treatment (filtration, chlorination, treatments plants) is often beyond financial means or environmental resources used for water ..
  69. SIGNALS FOR RENAL ENDOTHELIAL CAPILLARY MORPHOGENESIS
    Jin Chen; Fiscal Year: 2001
    ..Finally, a series of chemical cross-linking studies and gel filtration electrophoresis experiments will be employed to investigate the state of oligomerization of LERK-2 following ..
  70. LUNG CAPILLARY PERMEABILITY WITH HIGH VASCULAR PRESSURES
    Mary Townsley; Fiscal Year: 1991
    ..to address five specific problems: (1) to characterize the relationship in the lung between the capillary filtration coefficient and the osmotic reflection coefficient, which describe the capillary permeability to fluid and ..
  71. Development of a 3D cell culture model of the glomerular filtration barrier
    LESLIE BRUGGEMAN; Fiscal Year: 2009
    The goal of this R21 application is to develop a three-dimensional (3D) model of the glomerular filtration barrier that incorporates the key cellular components, podocytes and endothelial cells, and matrix that models the glomerular ..
  72. Intercellular Signaling in Obstructive Nephropathy
    ROBERT CHEVALIER; Fiscal Year: 2005
    ..obstruction (UUO), there is marked activation of the intrarenal renin-angiotensin system, and heterogeneity in filtration among individual nephrons...
  73. MECHANISMS OF FLUID BALANCE IN LOWER VERTEBRATE LUNGS
    ALLAN SMITS; Fiscal Year: 1991
    ..Rates of pulmonary fluid filtration in non-diseased amphibians and reptiles equal or exceed those of humans afflicted with pulmonary edema, ..
  74. PATHOPHYSIOLOGY OF AIDS GLOMERULOPATHY
    Bryan Myers; Fiscal Year: 1992
    ..Morphometric determinations, including glomerular filtration surface area and epithelial filtration slit density will be correlated with lowered GFR and ultrafiltration ..
  75. THYROXINE BINDING PROTEIN AND HORMONE UTILIZATION
    KENNETH STERLING; Fiscal Year: 1980
    ..Fractionation of mitochondrial membrane protein entails an initial step of Sephadex G-200 gel filtration. The large molecular weight fraction (approximately 150,000) binds T3 with association constant (KA) of 10 to ..