hip prosthesis

Summary

Summary: Replacement for a hip joint.

Top Publications

  1. ncbi Long-term results with cementless Fitek (or Fitmore) cups
    Piergiorgio Marchetti
    Clinica Ortopedica, Istituto Ortopedico Rizzoli, Bologna, Italy
    J Arthroplasty 20:730-7. 2005
  2. ncbi Sonication of removed hip and knee prostheses for diagnosis of infection
    Andrej Trampuz
    Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    N Engl J Med 357:654-63. 2007
  3. ncbi Guidelines for standardization of radiostereometry (RSA) of implants
    Edward R Valstar
    Department of Orthopaedics, Leiden University Medical Center, The Netherlands
    Acta Orthop 76:563-72. 2005
  4. ncbi Six-year results of a prospective study of metal ion levels in young patients with metal-on-metal hip resurfacings
    J Daniel
    The McMinn Centre, 25 Highfield Road, Birmingham B15 3DP, UK
    J Bone Joint Surg Br 91:176-9. 2009
  5. pmc Uncemented and cemented primary total hip arthroplasty in the Swedish Hip Arthroplasty Register
    Nils P Hailer
    Department of Orthopaedics, Institute of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Acta Orthop 81:34-41. 2010
  6. ncbi Hip contact forces and gait patterns from routine activities
    G Bergmann
    Biomechanics Laboratory, Benjamin Frunklin School of Medicine, Free University of Berlin, Hindenburgdamm 30, 12203, Berlin, Germany
    J Biomech 34:859-71. 2001
  7. pmc Infection after primary hip arthroplasty: a comparison of 3 Norwegian health registers
    Håvard Dale
    The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 82:646-54. 2011
  8. ncbi Sensitivity and specificity of blood cobalt and chromium metal ions for predicting failure of metal-on-metal hip replacement
    A J Hart
    Imperial College London, Department of Musculoskeletal Surgery, Charing Cross Hospital Campus, Fulham Palace Road, London W6 8RF, UK
    J Bone Joint Surg Br 93:1308-13. 2011
  9. ncbi The operation of the century: total hip replacement
    Ian D Learmonth
    Department of Orthopaedics, Bristol Royal Infirmary, Bristol BS2 8HW, UK
    Lancet 370:1508-19. 2007
  10. pmc Early migration characteristics of a hydroxyapatite-coated femoral stem: an RSA study
    David Campbell
    Orthopaedic Unit, Repatriation General Hospital, Adelaide, South Australia, Australia
    Int Orthop 35:483-8. 2011

Detail Information

Publications417 found, 100 shown here

  1. ncbi Long-term results with cementless Fitek (or Fitmore) cups
    Piergiorgio Marchetti
    Clinica Ortopedica, Istituto Ortopedico Rizzoli, Bologna, Italy
    J Arthroplasty 20:730-7. 2005
    ..7 years, was 100% (end point: revision for any cause). Fitek cup showed good clinicoradiographic results...
  2. ncbi Sonication of removed hip and knee prostheses for diagnosis of infection
    Andrej Trampuz
    Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    N Engl J Med 357:654-63. 2007
    ..We hypothesized that culturing of samples obtained from the prosthesis would improve the microbiologic diagnosis of prosthetic-joint infection...
  3. ncbi Guidelines for standardization of radiostereometry (RSA) of implants
    Edward R Valstar
    Department of Orthopaedics, Leiden University Medical Center, The Netherlands
    Acta Orthop 76:563-72. 2005
    ..Such a protocol-also including other recognized clinical outcome parameters-will reduce the risk of implanting potentially inferior prostheses on a large scale...
  4. ncbi Six-year results of a prospective study of metal ion levels in young patients with metal-on-metal hip resurfacings
    J Daniel
    The McMinn Centre, 25 Highfield Road, Birmingham B15 3DP, UK
    J Bone Joint Surg Br 91:176-9. 2009
    ..Subsequently there is a decreasing trend in excretion of both cobalt and chromium. The levels of cobalt and chromium in whole blood also show a significant increase at one year, followed by a decreasing trend until the sixth year...
  5. pmc Uncemented and cemented primary total hip arthroplasty in the Swedish Hip Arthroplasty Register
    Nils P Hailer
    Department of Orthopaedics, Institute of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Acta Orthop 81:34-41. 2010
    ..We therefore analyzed implant survival of cemented and uncemented THA, and whether the modes of failure differ between the two methods of fixation...
  6. ncbi Hip contact forces and gait patterns from routine activities
    G Bergmann
    Biomechanics Laboratory, Benjamin Frunklin School of Medicine, Free University of Berlin, Hindenburgdamm 30, 12203, Berlin, Germany
    J Biomech 34:859-71. 2001
    ..Because the hip joint loading during all other common activities of most hip patients are comparably small (except during stumbling), implants should mainly be tested with loading conditions that mimic walking and stair climbing...
  7. pmc Infection after primary hip arthroplasty: a comparison of 3 Norwegian health registers
    Håvard Dale
    The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 82:646-54. 2011
    ..We investigated differences in risk patterns between surgical site infection (SSI) and revision due to infection after primary total hip arthroplasty (THA) and hemiarthroplasty (HA)...
  8. ncbi Sensitivity and specificity of blood cobalt and chromium metal ions for predicting failure of metal-on-metal hip replacement
    A J Hart
    Imperial College London, Department of Musculoskeletal Surgery, Charing Cross Hospital Campus, Fulham Palace Road, London W6 8RF, UK
    J Bone Joint Surg Br 93:1308-13. 2011
    ..Blood metal ions had good discriminant ability to separate failed from well-functioning hip replacements. The MHRA cut-off level of 7 ppb provides a specific test but has poor sensitivity...
  9. ncbi The operation of the century: total hip replacement
    Ian D Learmonth
    Department of Orthopaedics, Bristol Royal Infirmary, Bristol BS2 8HW, UK
    Lancet 370:1508-19. 2007
    ..Universal economic constraints in healthcare services dictate that further developments in total hip replacement will be governed by their cost-effectiveness...
  10. pmc Early migration characteristics of a hydroxyapatite-coated femoral stem: an RSA study
    David Campbell
    Orthopaedic Unit, Repatriation General Hospital, Adelaide, South Australia, Australia
    Int Orthop 35:483-8. 2011
    ..The results from this study can be compared with those from novel cementless stem designs to help predict the long-term outcome one may expect from new cementless stem designs...
  11. pmc A retrospective comparative study of mortality and causes of death among patients with metal-on-metal and metal-on-polyethylene total hip prostheses in primary osteoarthritis after a long-term follow-up
    Tuomo Visuri
    Research Institute of Military Medicine, Helsinki, Finland
    BMC Musculoskelet Disord 11:78. 2010
    ..We analyzed the causes of total and site-specific mortality among a cohort of patients with MM and with metal-on-polyethylene (MP) THA after a long follow-up time...
  12. pmc Notes on the use and interpretation of radiostereometric analysis
    Brian Derbyshire
    Centre for Hip Surgery, Wrightington Hospital, Appley Bridge, UK
    Acta Orthop 80:124-30. 2009
    ..Alternatives are proposed, and a statistical analysis is presented, from which a sample size of 50 is recommended for screening of newly introduced prostheses...
  13. ncbi Role of rifampin for treatment of orthopedic implant-related staphylococcal infections: a randomized controlled trial. Foreign-Body Infection (FBI) Study Group
    W Zimmerli
    Department of Internal Medicine, University Hospitals, Basel, Switzerland
    JAMA 279:1537-41. 1998
    ..Rifampin-containing regimens are able to cure staphylococcal implant-related infections based on in vitro and in vivo observations. However, this evidence has not been proven by a controlled clinical trial...
  14. ncbi Pseudotumours associated with metal-on-metal hip resurfacings
    H Pandit
    Nuffield Orthopaedic Centre, Oxford, England
    J Bone Joint Surg Br 90:847-51. 2008
    ..We are concerned that with time the incidence of these pseudotumours may increase. Further investigation is required to define their cause...
  15. pmc Cemented versus uncemented hemiarthroplasty for displaced femoral neck fractures
    Wender Figved
    Orthopaedic Centre, Ulleval University Hospital, Oslo, Norway
    Clin Orthop Relat Res 467:2426-35. 2009
    ..The rates of complications and mortality were similar between groups. Both arthroplasties may be used with good results after displaced femoral neck fractures...
  16. ncbi Metal-on-metal bearings: the evidence so far
    F S Haddad
    Department of Orthopaedics, University College Hospital, 235 Euston Road, London NW1 2BU, UK
    J Bone Joint Surg Br 93:572-9. 2011
    ..This review examines the literature and contemporary presentations on current clinical dilemmas in metal-on-metal hip replacement...
  17. ncbi Wear mechanisms in metal-on-metal bearings: the importance of tribochemical reaction layers
    Markus A Wimmer
    Department of Orthopedic Surgery, Rush University Medical Center, 1653 West Congress Parkway, Chicago, Illinois 60612, USA
    J Orthop Res 28:436-43. 2010
    ..This novel finding of a mechanically mixed zone of nanocrystalline metal and organic constituents provides the basis for understanding particle release and may help in identifying new strategies to reduce MoM wear...
  18. ncbi Accelerating failure rate of the ASR total hip replacement
    D J Langton
    Northern Deanery, Goldcrest Way, Newcastle upon Tyne NE15 8NY, UK
    J Bone Joint Surg Br 93:1011-6. 2011
    ..Our results suggest that wear at the modular junction is an important factor in the development of adverse tissue reactions after implantation of a large-diameter MoM THR...
  19. pmc Risk of cancer with metal-on-metal hip replacements: population based study
    Keijo T Mäkelä
    Department of Orthopaedics and Traumatology, Surgical Hospital, Turku University Hospital, FI 20701 Turku, Finland
    BMJ 345:e4646. 2012
    ..To assess the risk of cancer associated with modern primary metal-on-metal hip replacements...
  20. ncbi Severe cobalt poisoning with loss of sight after ceramic-metal pairing in a hip--a case report
    Wolfram Steens
    Franziskus Hospital Münster, Orthopädie, Germany
    Acta Orthop 77:830-2. 2006
  21. pmc Risk of cancer in first seven years after metal-on-metal hip replacement compared with other bearings and general population: linkage study between the National Joint Registry of England and Wales and hospital episode statistics
    Alison J Smith
    Musculosketal Research Unit, School of Clinical Sciences, University of Bristol, Avon Orthopaedic Centre, Bristol BS10 5NB, UK
    BMJ 344:e2383. 2012
    ....
  22. ncbi Ten-year clinical, radiological and metal ion analysis of the Birmingham Hip Resurfacing: from a single, non-designer surgeon
    J P Holland
    Freeman Hospital, Freeman Road, High Heaton, Newcastle upon Tyne, Tyne and Wear NE7 7DN, UK
    J Bone Joint Surg Br 94:471-6. 2012
    ..The overall results were consistent with data produced from other centres in that the clinical outcome of large male patients was extremely encouraging, whereas the survival of the smaller joints was less satisfactory...
  23. pmc Cancer risk is not increased after conventional hip arthroplasty
    Tuomo Visuri
    Research Department, Centre for Military Medicine, Finland
    Acta Orthop 81:77-81. 2010
    ..A long latent period is required for solid tumors. We therefore re-analyzed a large THA cohort for cancer...
  24. ncbi Five-year results of the ASR XL Acetabular System and the ASR Hip Resurfacing System: an analysis from the Australian Orthopaedic Association National Joint Replacement Registry
    Richard N de Steiger
    Australian Orthopaedic Association National Joint Replacement Registry, Discipline of Public Health, University of Adelaide, Adelaide, SA, Australia
    J Bone Joint Surg Am 93:2287-93. 2011
    ..This report summarizes an analysis by the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) of the outcome of arthroplasties involving the ASR prostheses...
  25. ncbi Serum metal ion levels after second-generation metal-on-metal total hip arthroplasty
    Takao Imanishi
    Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie, 514 8507, Japan
    Arch Orthop Trauma Surg 130:1447-50. 2010
    ..We investigated serum levels of cobalt and chromium ions in patients with successfully implanted second-generation metal-on-metal total hip arthroplasty (THA) using PINNACLE-A (DePuy, Warsaw, IN, USA)...
  26. pmc The John Charnley Award: risk factors for cup malpositioning: quality improvement through a joint registry at a tertiary hospital
    Mark C Callanan
    Harris Orthopaedic Laboratory, Massachusetts General Hospital, 55 Fruit Street, GRJ 1206, Boston, MA 02114, USA
    Clin Orthop Relat Res 469:319-29. 2011
    ..Few studies have examined factors that affect acetabular cup positioning. Since cup positioning has been linked to dislocation and increased bearing surface wear, these factors affecting cup position are important considerations...
  27. pmc Competing risks survival analysis applied to data from the Australian Orthopaedic Association National Joint Replacement Registry
    Marianne H Gillam
    School of Population Health and Clinical Practice, University of Adelaide, Adelaide, Australia
    Acta Orthop 81:548-55. 2010
    ..In the presence of a competing risk such as death, KM is known to overestimate the probability of revision. We investigated the degree to which the risk of revision is overestimated in registry data...
  28. pmc Inferior outcome after hip resurfacing arthroplasty than after conventional arthroplasty. Evidence from the Nordic Arthroplasty Register Association (NARA) database, 1995 to 2007
    Per Erik Johanson
    Department of Orthopedics, Sahlgrenska University Hospital, University of Gothenburg, Sweden
    Acta Orthop 81:535-41. 2010
    ..We therefore determined the outcome of HRA in the NARA database, which is common to all 3 countries, and compared it to the outcome of conventional total hip arthroplasty (THA)...
  29. ncbi Birmingham hip resurfacing: a minimum follow-up of ten years
    R B C Treacy
    Royal Orthopaedic Hospital, Bristol Road South, Northfield, Birmingham B31 2AP, UK
    J Bone Joint Surg Br 93:27-33. 2011
    ....
  30. pmc Mid-term results of 155 patients treated with a collum femoris preserving (CFP) short stem prosthesis
    Daniel Briem
    Endoclinic Hamburg, Hamburg, Germany
    Int Orthop 35:655-60. 2011
    ..With regard to outcome, survivorship and complication rate, the medium-term results of the CFP prosthesis are promising...
  31. ncbi Eight- to ten-year clinical and radiographic outcome of a porous tantalum monoblock acetabular component
    George Macheras
    Department of Orthopaedics, IKA Hospital, Athens, Greece
    J Arthroplasty 24:705-9. 2009
    ..There were 7 (4.5%) postoperative complications all unrelated to the acetabular component...
  32. ncbi Nationwide study of cancer risk among hip replacement patients in Sweden
    L B Signorello
    International Epidemiology Institute, Rockville, MD 20850, USA
    J Natl Cancer Inst 93:1405-10. 2001
    ....
  33. ncbi Femoral head size is a risk factor for total hip luxation: a study of 42,987 primary hip arthroplasties from the Norwegian Arthroplasty Register
    Sven Byström
    Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop Scand 74:514-24. 2003
    ..A posterior approach increased the risk of revision more than a lateral one (FRR 1.9, 95% CI 1.4-2.5). Gender, trochanteric osteotomy and duration of the operation did not affect the results...
  34. pmc Hip arthroplasty in patients younger than 30 years: excellent ten to 16-year follow-up results with a HA-coated stem
    H Wangen
    Department of Orthopaedics, Rikshospitalet Radiumhospitalet Medical Centre, 0027, Oslo, Norway
    Int Orthop 32:203-8. 2008
    ..In this study, we evaluated the results of total 49 hip replacements (THRs) using an uncemented total hip prosthesis in 44 patients (28 females) who were 30 years or younger (range: 15-30 years)...
  35. pmc Risk factors for revision due to infection after primary total hip arthroplasty. A population-based study of 80,756 primary procedures in the Danish Hip Arthroplasty Registry
    Alma B Pedersen
    Department of Clinical Epidemiology, Aarhus University Hospital, Arhus, Denmark
    Acta Orthop 81:542-7. 2010
    ..We therefore studied patient- and surgery-related risk factors for revision due to infection after primary THA in a population-based setting...
  36. ncbi Ceramic liner fracture after cementless alumina-on-alumina total hip arthroplasty
    Yong Chan Ha
    Department of Orthopaedic Surgery, Gyeongsang National University Colleg of Medicine, Chinju, South Korea
    Clin Orthop Relat Res 458:106-10. 2007
    ..Early ceramic liner fracture was associated with impingement associated with excessive anteversion of the acetabular cup in Korean patients who habitually squat...
  37. ncbi Comparison of the uncemented Cone and the cemented Bimetric hip prosthesis in young patients with osteoarthritis: an RSA, clinical and radiographic study
    Håkan Ström
    Department of Orthopedics, University of Uppsala, Sweden
    Acta Orthop 77:71-8. 2006
    ..There is no consensus as to whether uncemented or cemented femoral stems should be used in younger patients. We compared the uncemented Cone stem to the cemented Bimetric stem in young patients with osteoarthritis...
  38. ncbi One-year prospective comparative study of three large-diameter metal-on-metal total hip prostheses: serum metal ion levels and clinical outcomes
    J F Lardanchet
    Department of Orthopaedic Surgery, North Amiens Teaching Hospital Center, 1, Place Victor Pauchet, 80000 Amiens, France
    Orthop Traumatol Surg Res 98:265-74. 2012
    ....
  39. ncbi Whole blood metal ion concentrations in correlation with activity level in three different metal-on-metal bearings
    Christophe A Pattyn
    Department of Orthopedic Surgery and Traumatology, Ghent University Hospital, Ghent, Belgium
    J Arthroplasty 26:58-64. 2011
    ..In conclusion, although the current second-generation metal bearings may show differences in ion release, more attention should be paid to the correlation between ion release and implant positioning...
  40. pmc Corrosion at the cone/taper interface leads to failure of large-diameter metal-on-metal total hip arthroplasties
    Heiko Meyer
    Department of Orthopaedics, Otto von Guericke University, Leipziger Str 44, 39108 Magdeburg, Germany
    Clin Orthop Relat Res 470:3101-8. 2012
    ..Metal-on-metal (MoM) THAs have reduced wear rates compared with metal-on-polyethylene. However, elevated serum metal ion levels and pseudotumors have been reported in large MoM articulations...
  41. pmc Early prosthetic joint infections treated with debridement and implant retention: 38 primary hip arthroplasties prospectively recorded and followed for median 4 years
    Marianne Westberg
    Department of Orthopaedics, Oslo University Hospital, Oslo, Norway
    Acta Orthop 83:227-32. 2012
    ..We have therefore analyzed the clinical and functional outcome of early PJIs treated with this procedure...
  42. pmc What is the evidence base to guide surgical treatment of infected hip prostheses? systematic review of longitudinal studies in unselected patients
    Andrew D Beswick
    School of Clinical Sciences, University of Bristol, Musculoskeletal Research Unit, Southmead Hospital, Southmead Road, Bristol, BS10 5NB, UK
    BMC Med 10:18. 2012
    ..Evidence is required regarding the comparative effectiveness of one-stage and two-stage revision to prevent reinfection after prosthetic joint infection...
  43. ncbi Pseudotumors in association with well-functioning metal-on-metal hip prostheses: a case-control study using three-dimensional computed tomography and magnetic resonance imaging
    Alister J Hart
    Department of Orthopaedic Surgery, Charing Cross Hospital Imperial College Healthcare NHS Trust and Imperial College London, Fulham Palace Road, London W6 8RF, United Kingdom
    J Bone Joint Surg Am 94:317-25. 2012
    ..The prevalence of pseudotumors in patients with a well-functioning metal-on-metal hip prosthesis is not well known...
  44. pmc Metal ion levels and functional results after either resurfacing hip arthroplasty or conventional metal-on-metal hip arthroplasty
    José M H Smolders
    Department of Orthopaedics, Hospital Rijnstate, Arnhem, The Netherlands
    Acta Orthop 82:559-66. 2011
    ....
  45. ncbi Comparison of surgical outcomes and implant wear between ceramic-ceramic and ceramic-polyethylene articulations in total hip arthroplasty
    Derek F Amanatullah
    Department of Orthopaedic Surgery, University of California at Davis Medical Center, Sacramento, California 95817, USA
    J Arthroplasty 26:72-7. 2011
    ..05). Lastly, there was no statistically significant difference in the dislocation or revision rate between the groups at the time of last clinical follow-up...
  46. ncbi Lymphocyte proliferation responses in patients with pseudotumors following metal-on-metal hip resurfacing arthroplasty
    Young Min Kwon
    Nuffield Department of Orthopaedic Surgery, University of Oxford, Windmill Road, Oxford OX3 7LD, United Kingdom
    J Orthop Res 28:444-50. 2010
    ..This suggests that systemic hypersensitivity type IV reactions, as measured by lymphocyte proliferation response to these metals, may not be the dominant biological reaction involved in the occurrence of the soft tissue pseudotumors...
  47. pmc Validity of frozen sections for analysis of periprosthetic loosening membranes
    Stephan W Tohtz
    Center for Musculoskeletal Surgery, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Clin Orthop Relat Res 468:762-8. 2010
    ..6%, specificity 100%, and accuracy 96.2%. Our data support a recommendation for use of intraoperative frozen sections for diagnosis of septic versus aseptic loosening in revision hip surgery...
  48. ncbi Cementless modular total hip arthroplasty with subtrochanteric shortening osteotomy for hips with developmental dysplasia
    Masaki Takao
    Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Japan
    J Bone Joint Surg Am 93:548-55. 2011
    ....
  49. pmc Two-stage total hip arthroplasty: how often does it control methicillin-resistant infection?
    Fay Leung
    Department of Orthopaedics, University of British Columbia, 3114 910 West 10th Avenue, Vancouver, BC V5Z 4E3, Canada
    Clin Orthop Relat Res 469:1009-15. 2011
    ..Methicillin-resistant hip infections are increasingly common. Reports of the surgical management of these patients using two-stage THA show variable control of infection, but all reports used static spacers...
  50. ncbi Isolated fracture of the ceramic head after third-generation alumina-on-alumina total hip arthroplasty
    Kyung Hoi Koo
    Department of Orthopaedic Surgery, Seoul National University College of Medicine, 28 Yeongeon dong, Jongno gu, Seoul 110 744, South Korea
    J Bone Joint Surg Am 90:329-36. 2008
    ..In the present multicenter study, we investigated ceramic head fractures in a cohort of patients who underwent third-generation alumina-on-alumina total hip arthroplasty...
  51. pmc Elevation of circulating HLA DR(+) CD8(+) T-cells and correlation with chromium and cobalt concentrations 6 years after metal-on-metal hip arthroplasty
    Nils P Hailer
    Department of Orthopedics, Institute of Surgical Sciences, Uppsala University Hospital, Sweden
    Acta Orthop 82:6-12. 2011
    ..We hypothesized that changes in lymphocyte subpopulations would be associated with elevated metal ion concentrations...
  52. ncbi Loosening and osteolysis associated with metal-on-metal bearings: A local effect of metal hypersensitivity?
    Joshua J Jacobs
    J Bone Joint Surg Am 88:1171-2. 2006
  53. ncbi Patient-related risk factors for periprosthetic joint infection and postoperative mortality following total hip arthroplasty in Medicare patients
    Kevin J Bozic
    Department of Orthopaedic Surgery, University of California San Francisco, 500 Parnassus, MU 320W, San Francisco, CA 94143 0728, USA
    J Bone Joint Surg Am 94:794-800. 2012
    ..S. Medicare patients undergoing total hip arthroplasty...
  54. pmc Hip resurfacing arthroplasty: short-term survivorship of 4,401 hips from the Finnish Arthroplasty Register
    Matti Seppänen
    Department of Orthopaedics and Traumatology, Turku University Hospital, Turku, Finland
    Acta Orthop 83:207-13. 2012
    ..We analyzed the short-term survival of 4,401 HRAs in the Finnish Arthroplasty Register...
  55. pmc Alloprosthetic composite is a suitable reconstruction after periacetabular tumor resection
    Davide Donati
    Orthopaedic Surgery, Department of Musculoskeletal Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy
    Clin Orthop Relat Res 469:1450-8. 2011
    ..However, while such composites restore anatomy and function of the pelvis the use of pelvic allografts is controversial and the durability is unknown...
  56. ncbi Total hip arthroplasty: to cement or not to cement the acetabular socket? A critical review of the literature
    N D Clement
    Department of Orthopaedics and Trauma, Royal Infirmary of Edinburgh, Little France, Edinburgh, UK
    Arch Orthop Trauma Surg 132:411-27. 2012
    ....
  57. ncbi Circulating levels of cobalt and chromium from metal-on-metal hip replacement are associated with CD8+ T-cell lymphopenia
    A J Hart
    Department of Musculoskeletal Surgery Charing Cross, Imperial College, London, England
    J Bone Joint Surg Br 91:835-42. 2009
    ....
  58. ncbi Migration pattern of a short femoral neck preserving stem
    S M Röhrl
    Department of Surgery and Perioperative Sciences, Umea University Hospital, Sweden
    Clin Orthop Relat Res 448:73-8. 2006
    ..The low migration of this short neck preserving stem suggests a favorable long-term outcome but longer followup is needed to substantiate this prediction. This design might become an alternative to standard stems and hip resurfacing...
  59. ncbi The seven-year wear of highly cross-linked polyethylene in total hip arthroplasty: a double-blind, randomized controlled trial using radiostereometric analysis
    Geraint E R Thomas
    Biomedical Research Unit, Headington, Oxford OX3 7LD, United Kingdom
    J Bone Joint Surg Am 93:716-22. 2011
    ....
  60. ncbi Characterization of the running-in period in total hip resurfacing arthroplasty: an in vivo and in vitro metal ion analysis
    Christian Heisel
    Laboratory of Biomechanics and Implant Research, Department of Orthopaedics, University of Heidelberg, Schlierbacher Landstrasse 200a, 69117 Heidelberg, Germany
    J Bone Joint Surg Am 90:125-33. 2008
    ..The goal of this study was to characterize the early running-in period in vivo and in vitro by characterizing metal ion levels...
  61. ncbi An analysis of metal ion levels in the joint fluid of symptomatic patients with metal-on-metal hip replacements
    K Davda
    Imperial College, Charing Cross Campus, Fulham Palace Road, London W6 8RF, UK
    J Bone Joint Surg Br 93:738-45. 2011
    ..Our results suggest that acid digestion of samples of synovial fluid samples is necessary to determine metal ion concentrations accurately so that meaningful comparisons can be made between studies...
  62. ncbi The effect of component size and orientation on the concentrations of metal ions after resurfacing arthroplasty of the hip
    D J Langton
    Joint Replacement Unit, University Hospital of North Tees, Hardwick, Stockton on Tees TS19 8PE, UK
    J Bone Joint Surg Br 90:1143-51. 2008
    ..Accurate positioning of the acetabular component intra-operatively is essential in order to reduce the concentration of metal ions in the blood after hip resurfacing arthroplasty with the Articular Surface Replacement implant...
  63. ncbi Failure rates of metal-on-metal hip resurfacings: analysis of data from the National Joint Registry for England and Wales
    Alison J Smith
    Orthopaedic Surgery, Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, UK
    Lancet 380:1759-66. 2012
    ..We assessed the survival of different sizes of metal-on-metal resurfacing in men and women, and compared this survival with those for conventional stemmed THRs...
  64. pmc Osteonecrosis following resurfacing arthroplasty
    Gösta Ullmark
    Department of Orthopedics, Gävle Hospital and Center for Research and Development, Uppsala University County Council of Gavleborg, Gavle, Sweden
    Acta Orthop 80:670-4. 2009
    ....
  65. pmc Cementless total hip arthroplasty with ceramic-on-ceramic bearing in patients younger than 45 years with femoral-head osteonecrosis
    Young Hoo Kim
    Joint Replacement Center of Korea, Ewha Womans University School of Medicine, Seoul, Korea
    Int Orthop 34:1123-7. 2010
    ..1-year follow-up in this series of young patients with femoral-head osteonecrosis...
  66. ncbi Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement
    R de Haan
    University Hospital Brussels, Laarbeeklaan 101, 1090 Brussels, Belgium
    J Bone Joint Surg Br 90:1291-7. 2008
    ..This is probably due to a greater risk of edge-loading...
  67. ncbi Serum cobalt and chromium elevations following hip resurfacing with the Cormet 2000 device
    D Gordon Allan
    Southern Illinois University, School of Medicine, Division of Orthopedics and Rehabilitation, Springfield, IL 62794 9679, USA
    J Surg Orthop Adv 16:12-8. 2007
    ..Future studies are needed to determine what serum Co/Cr levels are of clinical concern, particularly in outlier cases...
  68. ncbi Decreased dislocation after revision total hip arthroplasty using larger femoral head size and posterior capsular repair
    Matthew T Hummel
    Department of Orthopaedic Surgery, University of Louisville, School of Medicine, Louisville, Kentucky 40202, USA
    J Arthroplasty 24:73-6. 2009
    ..7%) (P < .05). Based on the results of this retrospective review, the authors recommend the use of both larger femoral head sizes and repair of any posterior capsular tissue available in patients undergoing revision hip arthroplasty...
  69. ncbi Survival of metal-on-metal hip resurfacing arthroplasty: a systematic review of the literature
    W van der Weegen
    Department of Orthopaedic Surgery, St Anna Hospital, Geldrop, The Netherlands
    J Bone Joint Surg Br 93:298-306. 2011
    ..None of the hip resurfacing arthroplasty implants used to date met the full ten-year NICE benchmark of survival. A total of 13 studies showed satisfactory survival compared with the three-year NICE benchmark...
  70. pmc A modular cementless stem vs. cemented long-stem prostheses in revision surgery of the hip: a population-based study from the Swedish Hip Arthroplasty Register
    Rudiger J Weiss
    Department of Molecular Medicine and Surgery, Section of Orthopaedics and Sports Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Acta Orthop 82:136-42. 2011
    ..In this paper, we review risk factors for the outcome of the Link MP stem and report implant survival compared to conventional cemented long-stem hip revision arthroplasties...
  71. ncbi The transverse acetabular ligament: an aid to orientation of the acetabular component during primary total hip replacement: a preliminary study of 1000 cases investigating postoperative stability
    H A P Archbold
    Outcomes Unit Musgrave Park Hospital, Stockmans Lane, Belfast BT9 7JB, Northern Ireland
    J Bone Joint Surg Br 88:883-6. 2006
    ..6%. This confirms our hypothesis that the transverse acetabular ligament can be used to determine the position of the acetabular component. The method has been used in both conventional and minimally-invasive approaches...
  72. pmc Alumina-on-alumina hip arthroplasty in patients younger than 30 years old
    R Nizard
    Department of Orthopaedic Surgery, Lariboisiere Hospital, 2, rue A Paré, 75010 Paris, France
    Clin Orthop Relat Res 466:317-23. 2008
    ..The main limiting factor in this series was the fixation of the acetabular component. However, improvements in the design and in the mode of fixation of this component should enhance long-term results...
  73. pmc What works best, a cemented or cementless primary total hip arthroplasty?: minimum 17-year followup of a randomized controlled trial
    Kristoff Corten
    London Health Sciences Centre, University Campus, 339 Windermere Road, London, ON N6A 5A5, Canada
    Clin Orthop Relat Res 469:209-17. 2011
    ..Total hip arthroplasty (THA) has been associated with high survival rates, but debate remains concerning the best fixation mode of THA...
  74. ncbi A prospective metal ion study of large-head metal-on-metal bearing: a matched-pair analysis of hip resurfacing versus total hip replacement
    Paul E Beaule
    The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada
    Orthop Clin North Am 42:251-7, ix. 2011
    ..51 vs 1.02, P = .002), and 2 years (3.77 vs 1.22, P<.001) following surgery. No differences in chromium ions were observed. Further research is required to determine the clinical significance of elevated serum cobalt ions...
  75. ncbi Randomised controlled trial comparing early migration of two collarless polished cemented stems using radiostereometric analysis
    R W McCalden
    London Health Sciences Centre, University of Western Ontario, 339 Windermere Road, London, Ontario, Canada N6A 5A5
    J Bone Joint Surg Br 92:935-40. 2010
    ..The subtle differences in designs may explain the different patterns of migration. Comparable migration with the Exeter stem suggests that the CPCS design will perform well in the long term...
  76. ncbi Exposure to chromium, cobalt and molybdenum from metal-on-metal total hip replacement and hip resurfacing arthroplasty
    Wolf Christoph Witzleb
    Department of Orthopaedic Surgery, Universty Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
    Acta Orthop 77:697-705. 2006
    ....
  77. pmc Thirty years of experience with alumina-on-alumina bearings in total hip arthroplasty
    Didier Hannouche
    Department of Orthopaedic Surgery and Traumatology, AP HP, Hôpital Lariboisière University Paris 7, 2 rue Ambroise Pare, 75010 Paris, France
    Int Orthop 35:207-13. 2011
    ..4% at ten years. However, concern remains over ceramic liner fracture and squeaking, which has been noted recently with increasing prevalence. This review will discuss the current knowledge on the use of alumina-on-alumina bearings...
  78. pmc Trabecular Metal cups for acetabular defects with 50% or less host bone contact
    Dror Lakstein
    Orthopedic Department, Division of Arthroplasty, Mount Sinai Hospital, 600 University Avenue, Suite 476A, Toronto, ON, M5G 1X5, Canada
    Clin Orthop Relat Res 467:2318-24. 2009
    ..The data suggest treatment of cavitary defects with less than 50% host bone contact using Trabecular Metal cups, without structural support by augments or structural bone grafts, is a reasonable option...
  79. ncbi Long-term results of the ABG-1 hydroxyapatite coated total hip arthroplasty: analysis of 111 cases with a minimum follow-up of 10 years
    R Bidar
    Department of Orthopaedics and Traumatology, Carémeau Teaching Hospital Center, place du Pr Robert Debré, 30029 Nimes Cedex 9, France
    Orthop Traumatol Surg Res 95:579-87. 2009
    ....
  80. pmc Surgical variables influence metal ion levels after hip resurfacing
    Nicholas M Desy
    Division of Orthopaedic Surgery, Montreal General Hospital, McGill University Health Centre, Montreal, QC, Canada
    Clin Orthop Relat Res 469:1635-41. 2011
    ..However, there exists some controversy regarding the effect of different surgical variables on the concentration of metal ions in whole blood of patients after hip resurfacing...
  81. ncbi Birmingham hip resurfacing: the prevalence of failure
    A D Carrothers
    Robert Jones and Agnes Hunt Orthopaedic Hospital, Gobowen, Oswestry SY10 7AG, UK
    J Bone Joint Surg Br 92:1344-50. 2010
    ..5 years, 0.02 to 11.0). There was a significantly shorter time to failure in men (mean 2.1 years, 0.4 to 8.7) compared with women (mean 3.6 years, 0.003 to 11.0) (p < 0.001)...
  82. ncbi Fixed or loose? Dichotomy in RSA data for cemented cups
    Per Aspenberg
    Department of Orthopaedics, IKE, Faculty of Health Sciences, Linkoping, Sweden
    Acta Orthop 79:467-73. 2008
    ..We present an exploratory evaluation of such a dichotomy using a mixture distribution algorithm...
  83. pmc Do ion levels in hip resurfacing differ from metal-on-metal THA at midterm?
    A Moroni
    Department II of Orthopaedics and Traumatology, Bologna University, Rizzoli Orthopaedic Institute, Via G C Pupilli 1, 40136 Bologna, Italy
    Clin Orthop Relat Res 469:180-7. 2011
    ..Metal-on-metal Birmingham hip resurfacing (MOM-BHR) is an alternative to metal-on-metal total hip arthroplasty (MOM-THA), especially for young and/or active patients. However, wear resulting in increased serum ion levels is a concern...
  84. ncbi Cementless Metasul metal-on-metal total hip arthroplasties at 13 years
    Filippo Randelli
    Divisione Ortopedia II, IRCCS Policlinico San Donato, 20097 San Donato Milanese, Milan, Italy
    J Arthroplasty 27:186-92. 2012
    ..Metal wear-related aseptic loosening was not the major reason for failure in our Metasul metal-on-metal THAs. Recurrent dislocation was the main reason for revision in our series...
  85. ncbi What is the benefit of introducing new hip and knee prostheses?
    Rajan Anand
    Discipline of Public Health, University of Adelaide, MDP DX650, 511 Australia SA 5005
    J Bone Joint Surg Am 93:51-4. 2011
    ..The underlying purpose of the introduction of new devices is to improve patient outcomes. This study was undertaken to determine how many new prostheses were associated with improved patient outcomes...
  86. ncbi Radiographic evaluation of a monoblock acetabular component: a multicenter study with 2- to 5-year results
    Thomas A Gruen
    Zonal Concepts, Wesley Chapel, Florida, USA
    J Arthroplasty 20:369-78. 2005
    ....
  87. ncbi The results of the titanium-coated RM acetabular component at 20 years: a long-term follow-up of an uncemented primary total hip replacement
    M Ihle
    Orthopädische Klinik Kassel, Wilhelmshöher Allee 345, D 34131 Kassel, Germany
    J Bone Joint Surg Br 90:1284-90. 2008
    ....
  88. ncbi The Exeter Universal cemented femoral component at 15 to 17 years: an update on the first 325 hips
    N C Carrington
    Princess Elizabeth Orthopaedic Centre, Exeter, England
    J Bone Joint Surg Br 91:730-7. 2009
    ..8) (0 to 48 worst-to-best scale) and the mean combined Harris pain and function score was 73.2 (SD 16.9). Radiological review showed excellent preservation of bone stock in the proximal femur and no failures of the femoral component...
  89. ncbi Increased surgical volume is associated with lower THA dislocation rates
    Todd C Battaglia
    Department of Orthopaedic Surgery, University of Virginia Health Sciences Center, Charlottesville, VA, USA
    Clin Orthop Relat Res 447:28-33. 2006
    ..This correlation appears to be stronger and is more clearly established for surgeon volumes than it is for hospital volumes...
  90. ncbi The Harris-Galante porous-coated, hemispherical, polyethylene-lined acetabular component in patients under 50 years of age: a 12- to 16-year review
    M R Utting
    Royal Perth Rehabilitation Hospital, 6 Selby Street, Shenton Park, Western Australia 6008, Australia
    J Bone Joint Surg Br 90:1422-7. 2008
    ..5 to 93.5) and for impending revision 55.3% (95% confidence interval 40.6 to 70) at 16 years. Uncemented acetabular components with polyethylene liners undergo silent lysis and merit regular long-term radiological review...
  91. ncbi Suppression of metal artifacts in CT using a reconstruction procedure that combines MAP and projection completion
    Catherine Lemmens
    Department of Nuclear Medicine, K U Leuven, B 3000 Leuven, Belgium
    IEEE Trans Med Imaging 28:250-60. 2009
    ..This constrained image is the basis for an image-based projection completion procedure. The algorithm was validated on simulations, phantom and patient data, and compared with other metal artifact reduction algorithms...
  92. ncbi [Management of periprosthetic infection]
    C Friesecke
    c o ENDO Klinik, Holstenstrasse 2, 22767, Hamburg, Deutschland
    Chirurg 79:777-92; quiz 793-4. 2008
    ....
  93. ncbi High-precision measurements of cementless acetabular components using model-based RSA: an experimental study
    Thomas Baad-Hansen
    Department of Orthopaedic Surgery, Aarhus University Hospital, Denmark
    Acta Orthop 78:463-9. 2007
    ..Within the last few years, new software systems have been developed to solve this problem. We compared the precision of 3 RSA systems in migration analysis of the acetabular component...
  94. ncbi Effect of swing phase load on metal-on-metal hip lubrication, friction and wear
    Sophie Williams
    School of Mechanical Engineering, Institute of Medical and Biological Engineering, University of Leeds, Leeds, LS2 9JT, UK
    J Biomech 39:2274-81. 2006
    ..This may explain some of the variations that have been observed with clinical wear rates...
  95. ncbi Future clinical and economic impact of revision total hip and knee arthroplasty
    Steven M Kurtz
    Exponent Incorporated, Philadelphia, PA 19104, USA
    J Bone Joint Surg Am 89:144-51. 2007
  96. ncbi Metal ion levels after metal-on-metal proximal femoral replacements: a 30-year follow-up
    E Dunstan
    Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex HA7 4LP, UK
    J Bone Joint Surg Br 87:628-31. 2005
    ..Stable metal-on-metal articulations showed much lower levels. Elevated levels of whole blood or urinary Co may be useful in identifying metal-on-metal articulations which are loose...
  97. ncbi Blood and urine metal ion levels in young and active patients after Birmingham hip resurfacing arthroplasty: four-year results of a prospective longitudinal study
    J Daniel
    The McMinn Centre, 25 Highfield Road, Edgbaston, Birmingham B15 3DP, UK
    J Bone Joint Surg Br 89:169-73. 2007
    ..The levels in this study provide a baseline against which the in vivo wear performance of newer bearings can be compared...
  98. ncbi A new CT method for measuring cup orientation after total hip arthroplasty: a study of 10 patients
    Henrik Olivecrona
    Department of Hand Surgery, Sodersjukhuset, SE 118 83 Stockholm, Sweden
    Acta Orthop Scand 75:252-60. 2004
    ..We present a method for determining the spatial orientation of the acetabular component after total hip arthroplasty (THA) using computed tomography...
  99. ncbi Retrieval analysis of 240 metal-on-metal hip components, comparing modular total hip replacement with hip resurfacing
    A Matthies
    Department of Musculoskeletal Surgery, Imperial College London, London, United Kingdom
    J Bone Joint Surg Br 93:307-14. 2011
    ..These findings show that failed metal-on-metal hip resurfacing and modular THRs have similar component wear rates and are both associated with raised pre-revision blood levels of metal ions...
  100. ncbi Alumina-alumina artificial hip joints. Part II: characterisation of the wear debris from in vitro hip joint simulations
    J L Tipper
    Medical and Biological Engineering, School of Molecular Biology and Biochemistry, University of Leeds, UK
    Biomaterials 23:3441-8. 2002
    ....
  101. ncbi Differences in the fretting corrosion of metal-metal and ceramic-metal modular junctions of total hip replacements
    Nadim James Hallab
    Department of Orthopedic Surgery, Rush Presbyterian St Lukes Medical Center, 1653 W Congress Parkway, Chicago, IL 60612, USA
    J Orthop Res 22:250-9. 2004
    ....

Research Grants30

  1. FDG-PET Imaging in painful Hip Prosthesis
    Abass Alavi; Fiscal Year: 2005
    ..of a single test that is highly accurate, and cost effective in the management of patients with painful total hip prosthesis. Current diagnostic tests including routine radiography, laboratory studies, and nuclear medicine procedures, ..
  2. Orthopaedic Wear Debris, Vitamin D, and Innate Immunity
    John S Adams; Fiscal Year: 2010
    ..PE particle-dependent inflammation and consequent, aseptic loosening of one or both of the components of the hip prosthesis. The overall aim of this proposal is 1] to ascertain the means by which the exfoliated PE particles engage ..
  3. NOVEL PROCESS FOR FABRICATING PROSTHETIC ALLOYS
    RAMAS RAMAN; Fiscal Year: 1993
    The goal of this program is to develop lower-cost, higher quality technology for hip prosthesis than currently available...
  4. PMMA PRECOATED INTRAMEDULLARY IMPLANTS
    Joon Park; Fiscal Year: 1980
    ..The femoral component of a hip prosthesis is pre-coated and cured with PMMA...
  5. Fatigue Crack Morphology in Cemented Hips
    Amos Race; Fiscal Year: 2002
    ....
  6. Effect of Femoral Stem Design om Cement Mantle Failure
    Amos Race; Fiscal Year: 2006
    ..Should these aims be met, the proposed model will be of great use in pre-clinical testing of novel cemented stem designs. ..
  7. Daily Activity of TKR Patients as Input for Wear Testing
    Markus Wimmer; Fiscal Year: 2008
    ..Based on the kinematic and kinetic in vivo data derived in the motion laboratory, we will calculate contact forces using a mathematical model of the artificial knee. [unreadable] [unreadable] [unreadable]..
  8. SYSTEMIC IMPLICATIONS OF TOTAL JOINT REPLACEMENT
    Joshua Jacobs; Fiscal Year: 2009
    ..abstract_text> ..
  9. Conference Support: The 13th International Drug Delivery Symposium
    David Grainger; Fiscal Year: 2007
    ..Support is requested both for selected speaker participation costs and 3 junior scientist poster travel awards. [unreadable] [unreadable] [unreadable]..
  10. Osteolysis and Implant Wear: Biological, Biomedical Engineering, and Surgical Pri
    Stuart Goodman; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  11. Implant/Construct Interactions in the Biomechanics of Total Hip Dislocation
    Thomas Brown; Fiscal Year: 2009
    ..Realistic finite element analysis is an ideal vehicle for systematically assessing the complex interactions of the many factors influencing dislocation propensity, toward the goal of reducing this troublesome complication. ..
  12. Prediction of Second Cancer Risks for Children Treated with Proton - vs. - Photon
    Wayne D Newhauser; Fiscal Year: 2010
    ..In the future, we expect that the lower-risk treatments will result in fewer second cancers and this will translate into longer, higher-quality lives for survivors of childhood cancer (presently 270,000 persons in the United States). ..
  13. Local Biomechanics of Median Nerve Insult in Carpal Tunnel Syndrome
    THOMAS DUDLEY BROWN; Fiscal Year: 2010
    ....
  14. AVS Biomaterials Interface Division Technical Program Support
    David Grainger; Fiscal Year: 2006
    ..A number of relevant leading scientists and engineers from companies working in these technology areas are also recruited to participate using the new "Commercial Challenge" podium opportunity. [unreadable] [unreadable] [unreadable]..
  15. Molecular Comparison of Macrophage Foreign Body Response
    David Grainger; Fiscal Year: 2007
    ..abstract_text> ..
  16. Infusion of Particles at Implant interfeces
    Stuart Goodman; Fiscal Year: 2006
    ..abstract_text> ..
  17. Revision THA Impaction Grafts:Effects of Bone Fusion
    Anneliese Heiner; Fiscal Year: 2003
    ..Successful conclusion of the proposed research will provide biomechanical data that will assist in the optimization of the impaction grafting process, thus improving the clinical success rate of this evolving procedure. ..
  18. Fatigue Resistant Crosslinked UHMWPE for Total Joints
    Orhun Muratoglu; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  19. Mechanisms of Third Body Acceleration of THA Wear
    Thomas Brown; Fiscal Year: 2005
    ..abstract_text> ..
  20. SURFACE INFLUENCES ON CELL SIGNALING AND PROLIFERATION
    David Grainger; Fiscal Year: 2002
    ....
  21. A Novel Load Sensing Tibial Prosthesis Design
    DARRYL D LIMA; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  22. Bioreactivity Markers in Total Hip Replacments
    Nadim Hallab; Fiscal Year: 2004
    ..Additionally, variable immunologic responses induced by implant degradation products (i.e. lymphocyte response to metal ions and monocyte/macrophage response to particulate debris) will be correlated with the development of osteolysis ..
  23. NONLINEAR COMPUTATIONAL BIOMECHANICS OF THE HIP
    Thomas Brown; Fiscal Year: 2004
    ..This partnership proposes to bring together a critical mass of engineers and surgeons, to achieve clinically grounded advances in nonlinear numerical simulations of surgery of the hip. ..
  24. Wear Analysis of Intervertebral Total Disc Replacements
    Thomas Brown; Fiscal Year: 2009
    ....
  25. The Emu as a Model for Necrotic Femoral Head Collapse
    Thomas Brown; Fiscal Year: 2006
    ....
  26. Aging and Fatigue Crack Growth in Dentin
    DWAYNE DALE AROLA; Fiscal Year: 2010
    ..These achievements should reduce the incidence of restorative failures associated with tooth fracture, resulting in billions of dollars in savings of health care costs, as well as a reduction in human suffering. ..
  27. ANALYSIS OF MULTIPLE INFORMANT DATA IN PSYCHIATRY
    SHARON LISE TERESA NORMAND; Fiscal Year: 2010
    ..These novel and innovative methods will improve the assessment of treatment effects and will contribute to improving the health of the population. ..
  28. MODELING TREATMENT USE & EFFECTIVENESS IN MENTAL ILLNESS
    Sharon Lise Normand; Fiscal Year: 2007
    ..The methodological advances from this research will enable researchers, policy makers, and methodologists to better characterize factors impacting technology innovation/exnovation and to expand the inferences for usual care. ..