auditory brain stem implants

Summary

Summary: Multi-channel hearing devices typically used for patients who have tumors on the COCHLEAR NERVE and are unable to benefit from COCHLEAR IMPLANTS after tumor surgery that severs the cochlear nerve. The device electrically stimulates the nerves of cochlea nucleus in the BRAIN STEM rather than the inner ear as in cochlear implants.

Top Publications

  1. ncbi Comprehensive evaluation of a child with an auditory brainstem implant
    Laurie S Eisenberg
    House Ear Institute, Los Angeles, California 90057, USA
    Otol Neurotol 29:251-7. 2008
  2. ncbi Subtonsillar placement of auditory brainstem implant
    Y Seki
    Department of Neurosurgery, Tokyo Kyosai Hospital, Tokyo, Japan
    Acta Neurochir Suppl 87:85-7. 2003
  3. ncbi Cochlear implant failure: is an auditory brainstem implant the answer?
    Vittorio Colletti
    ENT Department, University of Verona, Policlinico G B Rossi, Verona, Italy
    Acta Otolaryngol 124:353-7. 2004
  4. ncbi Auditory brainstem implants: surgical aspects
    Jose N Fayad
    House Clinic, Los Angeles, CA 90057, USA
    Adv Otorhinolaryngol 64:144-53. 2006
  5. ncbi Auditory brainstem implants
    Marc S Schwartz
    House Clinic, Los Angeles, California 90057, USA
    Neurotherapeutics 5:128-36. 2008
  6. ncbi Open set speech perception with auditory brainstem implant?
    Vittorio Colletti
    Department of Otolaryngology, University of Verona, Verona, Italy
    Laryngoscope 115:1974-8. 2005
  7. ncbi Electrical stimulation of the midbrain for hearing restoration: insight into the functional organization of the human central auditory system
    Hubert H Lim
    Otorhinolaryngology Department, Hannover Medical University, 30625 Hannover, Germany
    J Neurosci 27:13541-51. 2007
  8. ncbi The auditory midbrain implant: a new auditory prosthesis for neural deafness-concept and device description
    Thomas Lenarz
    Otorhinolaryngology Department, Medical University of Hannover, Germany
    Otol Neurotol 27:838-43. 2006
  9. pmc Auditory midbrain implant: a review
    Hubert H Lim
    Department of Biomedical Engineering, University of Minnesota, Minneapolis
    Trends Amplif 13:149-80. 2009
  10. ncbi Optimizing the clinical fit of auditory brain stem implants
    Christopher J Long
    MRC Cognition and Brain Sciences Unit, Cambridge, United Kingdom
    Ear Hear 26:251-62. 2005

Research Grants

Scientific Experts

Detail Information

Publications121 found, 100 shown here

  1. ncbi Comprehensive evaluation of a child with an auditory brainstem implant
    Laurie S Eisenberg
    House Ear Institute, Los Angeles, California 90057, USA
    Otol Neurotol 29:251-7. 2008
    ..The goal of this evaluation was to obtain insight into possible benefits derived from the ABI and to begin developing assessment protocols for pediatric clinical trials...
  2. ncbi Subtonsillar placement of auditory brainstem implant
    Y Seki
    Department of Neurosurgery, Tokyo Kyosai Hospital, Tokyo, Japan
    Acta Neurochir Suppl 87:85-7. 2003
    ..Hearing in pure tone average was maintained almost at the preoperative level. We present a new use of this approach in placing the electrode and discuss its advantages...
  3. ncbi Cochlear implant failure: is an auditory brainstem implant the answer?
    Vittorio Colletti
    ENT Department, University of Verona, Policlinico G B Rossi, Verona, Italy
    Acta Otolaryngol 124:353-7. 2004
    ..To investigate the auditory rehabilitative results achieved in five patients with cochlear implants (CIs) who subsequently received, due to poor results, auditory brainstem implants (ABIs)...
  4. ncbi Auditory brainstem implants: surgical aspects
    Jose N Fayad
    House Clinic, Los Angeles, CA 90057, USA
    Adv Otorhinolaryngol 64:144-53. 2006
    ..The surgical anatomy of the nucleus and surgical placement of the ABI in patients with neurofibromatosis type 2 are described, and surgical considerations in this group of challenging patients are detailed...
  5. ncbi Auditory brainstem implants
    Marc S Schwartz
    House Clinic, Los Angeles, California 90057, USA
    Neurotherapeutics 5:128-36. 2008
    ..We discuss future directions in central implants for hearing, including the penetrating ABI, the use of ABI in nontumor patients, and the auditory midbrain implant...
  6. ncbi Open set speech perception with auditory brainstem implant?
    Vittorio Colletti
    Department of Otolaryngology, University of Verona, Verona, Italy
    Laryngoscope 115:1974-8. 2005
    ..In the present study, a series of psychophysical tests were administered to determine the cause of the difference in performance between tumor (T) and nontumor (NT) ABI patients...
  7. ncbi Electrical stimulation of the midbrain for hearing restoration: insight into the functional organization of the human central auditory system
    Hubert H Lim
    Otorhinolaryngology Department, Hannover Medical University, 30625 Hannover, Germany
    J Neurosci 27:13541-51. 2007
    ..These findings provide some insight into how we may need to stimulate the midbrain to improve hearing performance with the AMI...
  8. ncbi The auditory midbrain implant: a new auditory prosthesis for neural deafness-concept and device description
    Thomas Lenarz
    Otorhinolaryngology Department, Medical University of Hannover, Germany
    Otol Neurotol 27:838-43. 2006
    ..Practical considerations for implementation of the AMI will also be discussed...
  9. pmc Auditory midbrain implant: a review
    Hubert H Lim
    Department of Biomedical Engineering, University of Minnesota, Minneapolis
    Trends Amplif 13:149-80. 2009
    ..Finally, several issues and hypotheses for why current patients obtain limited speech perception along with several feasible solutions for improving AMI implementation are presented...
  10. ncbi Optimizing the clinical fit of auditory brain stem implants
    Christopher J Long
    MRC Cognition and Brain Sciences Unit, Cambridge, United Kingdom
    Ear Hear 26:251-62. 2005
    To develop and implement a new audiological fitting procedure for auditory brain stem implants (ABIs), based on an efficient algorithm, and to compare it with two procedures presently used in clinical practice.
  11. ncbi Cochlear nucleus auditory prostheses
    D B McCreery
    Huntington Medical Research Institutes, Neural Engineering Program, 734 Fairmount Avenue, Pasadena, CA 91105, United States
    Hear Res 242:64-73. 2008
    ..This suggests that the cochlear nuclei of the NF2 patients are damaged by the disease process or during surgical removal of the tumor...
  12. ncbi Distribution of Fos-like immunoreactivity in the auditory pathway evoked by bipolar electrical brainstem stimulation
    Hideo Takagi
    Department of Otolaryngology, Tokyo Medical University, Tokyo 160 0023, Japan
    Acta Otolaryngol 124:907-13. 2004
    ..However, little work has been done on the effect of the ABI on the mammalian auditory pathway. The aim of this study was to demonstrate the effect of the ABI using Fos-like immunoreactivity...
  13. ncbi MRI compatibility issues in otology
    Michael H Fritsch
    Department of Otolaryngology Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Curr Opin Otolaryngol Head Neck Surg 15:335-40. 2007
    ..This review examines the specific issues and the conclusions of 33 referenced studies examining those issues...
  14. ncbi Auditory brainstem implant in posttraumatic cochlear nerve avulsion
    V Colletti
    ENT Department, University of Verona, Verona, Italy
    Audiol Neurootol 9:247-55. 2004
    ....
  15. ncbi Cochlear and brainstem implantation
    Elizabeth H Toh
    House Ear Clinic, 8162 Manitoba Street, 316, Playa Del Ray, CA 90293, USA
    Otolaryngol Clin North Am 35:325-42. 2002
    ..Most patients undergoing implantation demonstrate improved lip-reading skills, and exceptional performers achieve understanding of open-set speech...
  16. ncbi History of cochlear implants and auditory brainstem implants
    Aage R Møller
    School of Behavioral and Brain Sciences, University of Texas at Dallas, 75083 0688, USA
    Adv Otorhinolaryngol 64:1-10. 2006
    ....
  17. ncbi Far-field responses to stimulation of the cochlear nucleus by microsurgically placed penetrating and surface electrodes in the cat
    S K Rosahl
    Department of Neurosurgery, Nordstadt Hospital, Hannover, Germany
    J Neurosurg 95:845-52. 2001
    ....
  18. ncbi C-Fos immunoreactivity mapping of the auditory system after electrical stimulation of the cochlear nerve in rats
    Makoto Nakamura
    Department of Neurosurgery, Nordstadt Hospital, Haltenhoffstr 41, 30167 Hannover, Germany
    Hear Res 184:75-81. 2003
    ..Future functional studies analyzing the effect of electrical stimulation of the central auditory system as performed by auditory brainstem implants could be investigated in detail by mapping c-Fos expression on cellular level...
  19. ncbi Electrical stimulation of the dorsal cochlear nucleus induces hearing in rats
    Jinsheng Zhang
    Department of Otolaryngology Head and Neck Surgery, 5E UHC, Wayne State University School of Medicine, 4201 Saint Antoine, Detroit, MI 48201, USA
    Brain Res 1311:37-50. 2010
    ..The novel ePPI behavioral paradigm may potentially be developed into an efficient method for testing hearing in animals with an implantable prosthesis...
  20. ncbi Recent advances in the treatment of sensorineural deafness
    E Murugasu
    Department of Otolaryngology, Singapore General Hospital
    Ann Acad Med Singapore 34:313-21. 2005
    ..Finally, we take a glimpse into the future prospects of stem cell treatment and hair cell regeneration with gene delivery to the inner ear for the treatment of sensorineural hearing loss...
  21. ncbi Auditory brainstem implants (ABIs)--20 years of clinical experience in Uppsala, Sweden
    Malin Siegbahn
    Departments of Otolaryngology and Neurosurgery, Uppsala University Hospital, Uppsala, Sweden
    Acta Otolaryngol 134:1052-61. 2014
    ..Importantly the patients must be motivated, given reasonable expectations of outcome and offered long-term rehabilitation with a considerable 'learn to listen' period with the implant device...
  22. ncbi Selective vulnerability of adult cochlear nucleus neurons to de-afferentation by mechanical compression
    Tetsuji Sekiya
    Department of Otolaryngology, Head and Neck Surgery, Kyoto University Graduate School of Medicine, Sakyou ku, Kyoto 606 8507, Japan
    Exp Neurol 218:117-23. 2009
    ..Thus, this experimental model may be promising to obtain not only the basic knowledge on auditory nerve/CN degeneration but also the information relevant to the application of cochlear or auditory brainstem implants...
  23. ncbi Update on long-term results with auditory brainstem implants in NF2 patients
    Sangeeta Maini
    Aberdeen Royal Infirmary, Forrester Hill Road, Aberdeen, AB25 2ZA, UK
    Cochlear Implants Int 10:33-7. 2009
    ..This study confirms that gradual improvement in performance occurs beyond one year post-implantation, as speech perception scores continued to improve...
  24. pmc CNAP To Predict Functional Cochlear Nerve Preservation in NF-2: Cochlear Implant or Auditory Brainstem Implant
    Enrico Piccirillo
    Gruppo Otologico, Otology and Skull Base Quaternary Referral Center, Piacenza Rome, Italy
    Skull Base 18:281-7. 2008
    ..To this end we propose that a multicenter trial be undertaken to further elucidate the role of intraoperative monitoring to determine the functional preservation of the cochlear nerve...
  25. ncbi [Hearing disorder. Mechanical management of hearing loss: cochlear implants and brain stem implants--current developments in the last 10 years]
    J Muller
    Schwerpunkt Cochlea Implantate und Hörprothetik, Klinik und Poliklinik Fur Hals, Nasen und Ohrenkranke der Universität Josef Schneider Strasse 11, 97080 Wurzburg
    Laryngorhinootologie 84:S60-9. 2005
  26. ncbi Optimizing fitting in children using objective measures such as neural response imaging and electrically evoked stapedius reflex threshold
    Gül Caner
    SB Izmir Research and Training Hospital, Ear Nose Throat Clinic, Izmir, Turkey
    Otol Neurotol 28:637-40. 2007
    ....
  27. ncbi Twenty-five years of auditory brainstem implants: perspectives
    J Kuchta
    Department of Neurosurgery, Cologne University Hospital, Germany
    Acta Neurochir Suppl 97:443-9. 2007
    ..These techniques may further improve auditory perceptual performance in ABI patients and provide hearing to a variety of types of central deafness...
  28. ncbi Progress in restoration of hearing with the auditory brainstem implant
    Vittorio Colletti
    ENT Department, University of Verona, Verona, Italy
    Prog Brain Res 175:333-45. 2009
    ..New guidelines are proposed for device selection for different etiologies and future research is suggested to further refine the process of matching an individual patient to the most appropriate implant device...
  29. ncbi Restoring hearing with active hearing implants
    Ph A Federspil
    University of Saarland, Department of Oto Rhino Laryngology, Homburg Saar, Germany
    Biomed Tech (Berl) 49:78-82. 2004
    ..CI replace inner ear function in deaf or almost deaf patients. This article gives an overview on the range of active hearing implants to restore hearing and outlines the future use of computer and robot aided surgery...
  30. ncbi Neurophysiologic basis for cochlear and auditory brainstem implants
    A R Møller
    Callier Center for Communication Disorders, School of Human Development, University of Texas at Dallas, 75235, USA
    Am J Audiol 10:68-77. 2001
    ..It is then pertinent to ask how many channels are needed. Because speech discrimination is very important, it is probably sufficient to use enough channels to separate formants from each other...
  31. ncbi [Hearing implants]
    Robert J Stokroos
    Maastricht Universitair Medisch Centrum, afd Keel, Neus Oorheelkunde, Maastricht
    Ned Tijdschr Geneeskd 157:A6927. 2013
    ..Furthermore, new implants aimed at treating tinnitus and loss of vestibular function have recently been developed...
  32. ncbi Neurofibromatosis 2: hearing restoration options
    Tatiana Alves Monteiro
    Department of Otorhinolaryngology Medical School of the University of São Paulo, SP, Brazil
    Braz J Otorhinolaryngol 78:128-34. 2012
    ..Neurofibromatosis 2 (NF2) is an autosomal dominant disease in which hearing loss is predominant. Auditory restoration is possible using cochlear implants (CI) or auditory brainstem implant (ABI)...
  33. pmc Temporal processing in the auditory system: insights from cochlear and auditory midbrain implantees
    Colette M McKay
    Audiology and Deafness Research Group, School of Psychological Sciences, University of Manchester, Manchester, M13 9PL, UK
    J Assoc Res Otolaryngol 14:103-24. 2013
    ....
  34. ncbi Historical Aspects of Inner Ear Anatomy and Biology that Underlie the Design of Hearing and Balance Prosthetic Devices
    Thomas R Van De Water
    Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida 33136 1015, USA
    Anat Rec (Hoboken) 295:1741-59. 2012
    ..severely hearing impaired and deaf patients to restore hearing and are known as cochlear implants and auditory brain stem implants. A prosthetic device for patients with balance disorders is being perfected and is in an animal model ..
  35. ncbi English consensus protocol evaluating candidacy for auditory brainstem and cochlear implantation in neurofibromatosis type 2
    James R Tysome
    Department of Otolaryngology, Cambridge University Hospitals NHS Foundation Trust, Cambridge Department of Genetics, Manchester Royal Infirmary, Manchester Department of Neurology, and Department of Otolaryngology, Guy s and St Thomas NHS Foundation Trust, London Department of Otolaryngology, Manchester Royal Infirmary, Manchester Department of Otolaryngology, National Hospital for Neurology and Neurosurgery, London Department of Neurology, John Radcliffe Hospital, Oxford Emmeline Centre for Hearing Implants, Cambridge University Hospitals NHS Foundation Trust, Cambridge Department of Neurosurgery, John Radcliffe Hospital, Oxford Department of Neurosurgery, Manchester Royal Infirmary, Manchester Department of Audiology, and Department of Neurosurgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge Department of Audiology, Manchester Royal Infirmary, Manchester Department of Otolaryngology, John Radcliffe Hospital, Oxford Department of Otolaryngology, Royal National Throat Nose and Ear Hospital and Department of Neurosurgery, King s College Hospital NHS Trust, London, U K
    Otol Neurotol 34:1743-7. 2013
    ..A national consensus protocol was produced in England as a guide for cochlear implantation (CI) and auditory brainstem implantation (ABI) in these patients...
  36. ncbi No easy target: anatomic constraints of electrodes interfacing the human cochlear nucleus
    Steffen K Rosahl
    Department of Neurosurgery, HELIOS Klinikum, Erfurt, Germany
    Neurosurgery 72:58-64; discussion 65. 2013
    ..Auditory brainstem implants have failed to produce consistent clinical results comparable to those with the cochlear implant, both with surface and penetrating electrodes...
  37. ncbi Trauma-specific insults to the cochlear nucleus in the rat
    Tetsuji Sekiya
    Department of Otolaryngology, Head and Neck Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    J Neurosci Res 90:1924-31. 2012
    ..These findings are important for enhancing the performance of cochlear implants and auditory brainstem implants, because diverse types of hearing loss can selectively affect neuronal degeneration of the CN...
  38. ncbi Retrolabyrinthine approach for surgical placement of auditory brainstem implants in children
    Ricardo Ferreira Bento
    Division of Otorhinolaryngology, University of Sao Paulo Medical School, Brazil
    Acta Otolaryngol 132:462-6. 2012
    ..The extended retrolabyrinthine approach (RLA) is a safe and reliable approach for auditory brainstem placement in children. The surgical landmarks to reach cochlear nucleus are adequately exposed by this approach...
  39. ncbi A model for auditory brain stem implants: bilateral surgical deafferentation of the cochlear nuclei in the macaque monkey
    Francisco Javier Cervera-Paz
    Departamento de Otorrinolaringologia, University of Navarra, Clinica Universitaria, Pamplona, Spain
    Ear Hear 28:424-33. 2007
    ..and irreversible sensorineural hearing loss (SNHL), which can only be overcome with individually-fitted auditory brain stem implants that directly stimulate the cochlear nuclei...
  40. ncbi Auditory brainstem implantation in 12- to 18-year-olds
    Steven R Otto
    House Ear Institute, Los Angeles, CA 90057, USA
    Arch Otolaryngol Head Neck Surg 130:656-9. 2004
    ....
  41. ncbi Use of a multichannel auditory brainstem implant for neurofibromatosis type 2
    Marc S Schwartz
    House Ear Clinic and House Ear Institute, Los Angeles, CA 90057, USA
    Stereotact Funct Neurosurg 81:110-4. 2003
    ..The degree of improvement varied considerably among patients. ABI is a useful device for deaf patients with NF 2. As measured by audiologic testing, many patients receive substantial benefit with regard to sound and speech comprehension...
  42. ncbi Management of hearing in pediatric NF2
    Taylor H Shepard
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Otol Neurotol 33:1066-70. 2012
    ..The unique nature of each case discussed will provide valuable guiding principles for the treating surgeon...
  43. ncbi Bilateral electric stimulation from auditory brainstem implants in a patient with neurofibromatosis type 2
    Henryk Skarzynski
    Institute of Physiology and Pathology of Hearing, Warsaw, Poland
    Med Sci Monit 15:CS100-4. 2009
    ..Recent developments in the field of electronic hearing prostheses have allowed for the introduction of auditory brainstem implants in patients with neurofibromatosis type 2...
  44. ncbi Auditory brainstem implants in NF2 patients: results and review of the literature
    Mario Sanna
    Department of Otology and Skull Base Surgery, Gruppo Otologico, Piacenza, Rome, Italy
    Otol Neurotol 33:154-64. 2012
    ..If the cochlear nerve is not preserved during tumor removal, the only hearing rehabilitation in these patients could be via an auditory brainstem implant (ABI)...
  45. ncbi Neuronal activity evoked in the inferior colliculus of the cat by surface macroelectrodes and penetrating microelectrodes implanted in the cochlear nucleus
    Douglas McCreery
    Huntington Medical Research Institutes, Pasadena, CA 91105, USA
    IEEE Trans Biomed Eng 57:1765-73. 2010
    ..This concordance helps to validate our cat model as a means of investigating the synergistic use of surface and penetrating electrodes in a clinical ABI...
  46. ncbi Bacterial meningitis secondary to stapes footplate malformation in a child with an auditory brainstem implant
    M Mandala
    ENT Department, University of Verona, Italy
    J Laryngol Otol 126:72-5. 2012
    ..We report a rare presentation of otogenic bacterial meningitis secondary to a stapes footplate malformation in a paediatric patient with an auditory brainstem implant...
  47. ncbi Auditory brainstem implants: how do they work?
    C Vincent
    Département d Otologie et d Otoneurologie, Universite de Lille 2, France
    Anat Rec (Hoboken) 295:1981-6. 2012
    ..For the majority of patients, this improvement is essentially obtained by an augmentation of lip reading performances. Speech comprehension without lip-reading is not as good as with cochlear implants...
  48. ncbi Cochlear and brainstem implantation. 2002
    Elizabeth H Toh
    Department of Otolaryngology, University of Pittsburgh, Eye and Ear Institute, Suite 500, Pittsburgh, PA 15213, USA
    Neurosurg Clin N Am 19:317-29, vii. 2008
    ..An update on implant devices, speech processing strategies, candidacy criteria, and perceptual performance are provided in this article...
  49. ncbi Outcome from surgery for vestibular schwannomas in children
    Stephen P MacNally
    Department of Neurosurgery, Salford Royal Hospital, Manchester, UK
    Br J Neurosurg 23:226-31. 2009
    ....
  50. ncbi A guide to the positioning of brainstem implants using intraoperative electrical auditory brainstem responses
    Barry Nevison
    Cochlear Europe Ltd, Addlestone, UK
    Adv Otorhinolaryngol 64:154-66. 2006
    ..In individuals with a large lateral recess, measuring other combinations may assist in sideways and rotational orientation of the electrode array...
  51. ncbi Auditory brainstem implant part II: subjective assessment of functional outcome
    Minoo Lenarz
    Department of Otolaryngology, Medical University of Hannover, Germany
    Otol Neurotol 23:694-7. 2002
    ..OBJECTIVE The purpose of this study was to present the patients' recommendations and judgments about their hearing and communication abilities with the help of the auditory brainstem implant...
  52. ncbi Medical and surgical considerations for implantable hearing prosthetic devices
    Peter C Weber
    Department of Otolaryngology and Communicative Disorders, Cleveland Clinic Foundation, OH 44195, USA
    Am J Audiol 11:134-8. 2002
    ..This article examines the medical and surgical aspects of four types of implantable hearing devices: bone-anchored hearing aid (BAHA), middle ear implants, cochlear implants, and auditory brainstem implants...
  53. ncbi Sending sound to the brain
    J P Rauschecker
    Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC 20007, USA
    Science 295:1025-9. 2002
    ....
  54. ncbi Long-term follow-up of infants (4-11 months) fitted with cochlear implants
    Liliana Colletti
    ENT Department, University of Verona, Verona, Italy
    Acta Otolaryngol 129:361-6. 2009
    ....
  55. ncbi [Optimization of microsurgical operation technique to insert auditory brainstem implants, taking into account the results of a morphometric study]
    R Quester
    Zentrum für Neurochirurgie, Klinikum der Universität zu Köln, Seminar für Psychiatrie der Heilpädagogischen Fakultät, Universitat zu Koln
    HNO 52:706-13. 2004
    ..However, there have been few studies on the topographical relations in the target region, particularly the floor of the IVth ventricle...
  56. ncbi Auditory brainstem implantation
    Levent Sennaroglu
    Department of Otolaryngology, Hacettepe University Medical Faculty, Ankara, Turkey
    Auris Nasus Larynx 39:439-50. 2012
    ..In the present review article history and development of ABI, indications, side selection criteria, surgery and audiological outcome are presented...
  57. ncbi Auditory brainstem implant outcomes and MAP parameters: report of experiences in adults and children
    Maria Valéria Schmidt Goffi-Gomez
    ENT Department at Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil
    Int J Pediatr Otorhinolaryngol 76:257-64. 2012
    ..Although the results has been extensively reported, the stimulation parameters involved behind the outcomes have received less attention...
  58. pmc Histopathological analysis of a 15-year user of an auditory brainstem implant
    Steven R Otto
    Department of Communications and Auditory Neuroscience, House Research Institute, Los Angeles, California, USA
    Laryngoscope 122:645-8. 2012
    ..There was good preservation of CN cell size, morphology, and packing density, a very favorable sign considering that a number of infants are now receiving ABIs...
  59. ncbi Surgical management of vestibular schwannomas and hearing rehabilitation in neurofibromatosis type 2
    James R Tysome
    Department of Otolaryngology, Cambridge University Hospitals NHS Trust, Cambridge, UK
    Otol Neurotol 33:466-72. 2012
    ..To report our approach to the surgical management of vestibular schwannomas (VSs) and hearing rehabilitation in neurofibromatosis Type 2 (NF2)...
  60. ncbi Electrophysiological mapping of the cochlear nucleus with multi-channel bipolar surface microelectrodes
    Kiyoshi Oda
    Department of Otolaryngology Head and Neck Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan
    Eur Arch Otorhinolaryngol 270:869-74. 2013
    ..Further study to clarify the optimal inter-electrode distance for humans is necessary before application to physiological mapping in the human cochlear nucleus...
  61. ncbi Auditory brainstem implants for neurofibromatosis type 2
    Liliana Colletti
    Department of Otolaryngology, University of Verona, Verona, Italy
    Curr Opin Otolaryngol Head Neck Surg 20:353-7. 2012
    ..This study will review the new developments and improving outcomes of the ABI...
  62. ncbi Rehabilitation of hearing and communication functions in patients with NF2
    J Kuchta
    Department of Neurosurgery, Department of ENT Surgery, University of Cologne, Cologne, Germany
    Acta Neurochir Suppl 79:109-11. 2002
    ..With auditory brain stem implants it is now possible to bypass both the cochlea and the 8th nerve and to stimulate the cochlear nucleus ..
  63. ncbi [Neurofibromatosis type 2 and auditory brainstem implantation]
    Torbjørn Elvsåshagen
    Avdeling for nevropsykiatri og psykosomatisk medisin, Nevroklinikken, Oslo universitetssykehus, Rikshospitalet 0027 Oslo og Institutt for psykiatri Det medisinske fakultet, Universitetet i Oslo, Norway
    Tidsskr Nor Laegeforen 129:1469-73. 2009
    ..Neurofibromatosis type 2 (NF2) is a rare and severe autosomal dominant disorder caused by mutations in a tumour suppressor gene. This article reviews NF2 and its treatment with auditory brainstem implantation...
  64. ncbi Auditory midbrain implant: a combined approach for vestibular schwannoma surgery and device implantation
    Amir Samii
    Department of Neurosurgery, International Neuroscience Institute, Hannover, Germany
    Otol Neurotol 28:31-8. 2007
    ....
  65. ncbi WE-G-217A-01: Fast Recovery Driven Equilibrium with Automated Switching to Avoid Artifacts
    H Edmonson
    Mayo Clinic, Rochester, MN
    Med Phys 39:3975. 2012
    ..Clinical images from a patient with bilateral auditory brainstem implants demonstrate potential artifacts introduced by FR, and the benefits of automatically avoiding unnecessary use of FR...
  66. ncbi The first successful case of hearing produced by electrical stimulation of the human midbrain
    Vittorio Colletti
    ENT, University of Verona, Verona, Italy
    Otol Neurotol 28:39-43. 2007
    ..Electrical stimulation of the inferior colliculus in the midbrain can provide a safe and efficacious alternative to auditory brainstem implants (ABIs)...
  67. ncbi [Use of the auditory brainstem neuroprosthesis in the Czech Republic]
    J Skrivan
    Klinika otorinolaryngologie a chirurgie hlavy a krku 1 LF UK a FNM, Praha
    Cas Lek Cesk 142:29-33. 2003
    ..Stimulation of auditory nuclei in the floor of the IVth ventricle is realized by an electrode array introduced during surgery in the lateral recess of the IVth ventricle...
  68. ncbi Deafness and the bionic ear
    V Colletti
    ENT Department, University of Verona, Verona, Italy
    Artif Cells Blood Substit Immobil Biotechnol 31:139-43. 2003
  69. ncbi The cochleovestibular nerve identified during auditory brainstem implantation in patients with narrow internal auditory canals: can preoperative evaluation predict cochleovestibular nerve deficiency?
    Mee Hyun Song
    Department of Otorhinolaryngology, Kwandong University College of Medicine, Goyang, South Korea
    Laryngoscope 121:1773-9. 2011
    ..To analyze the value of preoperative diagnostic tools in predicting the status of the cochleovestibular nerve (CVN) in patients with narrow internal auditory canals (IAC)...
  70. ncbi [Possibility of hearing preservation treatment by patient suffered from neurofibromatosis type 2: case report]
    Barbara Jamróz
    Katedra i Klinika Otolaryngologii Warszawskiego Uniwersytetu Medycznego
    Otolaryngol Pol 64:114-7. 2010
    ..The aim of the study is case report of the patient suffered from bilateral vestibular schwannoma. Early diagnosis and therapy enable hearing preservation and good facial nerve function...
  71. ncbi Trigeminal neuralgia resulting from auditory brainstem implant cable compression
    Marc S Schwartz
    House Clinic, Los Angeles, California, USA
    J Neurosurg 114:186-8. 2011
    ..This is the first report of an ABI cable becoming displaced, resulting in neurovascular compression. This case demonstrates that trigeminal neuralgia can result from nonvascular compression of the trigeminal nerve...
  72. ncbi [Clinical application of the multichannel auditory brainstem implant]
    H Wu
    Department of Otolaryngology, Beaujon Hospital, University Paris 7, 92110 Clichy, France
    Zhonghua Er Bi Yan Hou Ke Za Zhi 35:123-5. 2000
    ..To investigate the surgical techniques and speech performance of multichannel auditory brainstem implant (ABI) in patients with bilateral acoustic neuromas (neurofibromatosis type 2)...
  73. ncbi Complications in auditory brainstem implant surgery in adults and children
    Vittorio Colletti
    ENT Department, University of Verona, Verona, Italy
    Otol Neurotol 31:558-64. 2010
    ..This article examines the complications encountered in ABI surgery in all patient groups...
  74. ncbi The multichannel auditory brainstem implant: how many electrodes make sense?
    Johannes Kuchta
    Department of Neurosurgery, Cologne University, Cologne, Germany
    J Neurosurg 100:16-23. 2004
    ..In this paper the authors critically analyze this assumption on the basis of a retrospective clinical study performed using the Nucleus 22 ABI surface electrode array...
  75. ncbi Our surgical experience with large vestibular schwannomas
    J Skrivan
    Department of Otorhinolaryngology, Head and Neck Surgery, Institute of Postgradual Education, Faculty Hospital Motol, V Uvalu 84, 150 06 Praha 5 Czech Republic
    Otolaryngol Pol 58:69-72. 2004
    ..Auditory brainstem implants bring a new chance of hearing after tumour removal in patients with NF2...
  76. ncbi Effects of phase duration and pulse rate on loudness and pitch percepts in the first auditory midbrain implant patients: Comparison to cochlear implant and auditory brainstem implant results
    H H Lim
    Otorhinolaryngology Department, Hannover Medical University, Carl Neuberg Str 1 Gebaeude K5, Ebene 1, Raum 4010, 30625 Hannover, Germany
    Neuroscience 154:370-80. 2008
    ..However, loudness adaptation occurs at multiple stages from the cochlea up to the midbrain...
  77. ncbi Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2
    D Gareth Evans
    St Mary s Hospital, Manchester, United Kingdom
    Clin Cancer Res 15:5032-9. 2009
    ..Meningiomas, ependymomas, and other benign central nervous system tumors are also common in NF2. The lack of effective treatments for NF2 marks an unmet medical need...
  78. ncbi Hearing restoration with auditory brainstem implants after radiosurgery for neurofibromatosis type 2
    M Kalamarides
    Department of Neurosurgery and Otolaryngology, Hopital Beaujon, Faculte Xavier Bichat, Universite Paris 7, France
    J Neurosurg 95:1028-33. 2001
    ..It is concluded that hearing function can be rehabilitated using ABIs in patients with NF2, even if radiosurgery fails to control the tumor growth...
  79. ncbi Poznań's program of cochlear and brainstem implantation: a general review
    W Szyfter
    Department of Otolaryngology, Karol Marcinkowski University School of Medical Sciences, Poznan, Poland
    Eur Arch Otorhinolaryngol 260:460-3. 2003
    ..Voice rehabilitation is often monitored by acoustic analysis using the Multi Dimensional Voice Program (MDVP)...
  80. ncbi [ADANO-Fall Meeting 2006 in Freiburg]
    S Hoth
    Hals Nasen Ohrenklinik, Universitatsklinikum Heidelberg, 69120, Im Neuenheimer Feld 400, Heidelberg
    HNO 55:5-11. 2007
  81. ncbi Auditory outcomes in tumor vs. nontumor patients fitted with auditory brainstem implants
    Vittorio Colletti
    Clinica ORL, Ospedale Policlinico, Verona, Italy
    Adv Otorhinolaryngol 64:167-85. 2006
    ..4) The ABI represents the tool for hearing rehabilitation in patients with profound hearing loss who cannot be fitted with cochlear implants...
  82. ncbi Physiological basis for cochlear and auditory brainstem implants
    Aage R Møller
    School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson 75083 0688, USA
    Adv Otorhinolaryngol 64:206-23. 2006
    ..Expression of neural plasticity makes the auditory nervous system adapt to the change in demands of processing of the information provided by cochlear implants...
  83. ncbi Polyester meshes and adhesive materials in the brain: comparative research in rats to optimize surgical strategy
    Ralf Quester
    Center for Neurosurgery, Stereotactic and Functional Neurosurgery Clinic, and General Neurosurgical Clinic, University of Cologne, Germany
    J Neurosurg 96:760-9. 2002
    ..The goal of this study was to determine the biocompatibility of polyester mesh electrode carriers for auditory brainstem implants with and without adhesives in a rat model...
  84. ncbi Auditory brainstem implantation: the University of Verona experience
    Vittorio Colletti
    ENT Department, University of Verona, Italy
    Otolaryngol Head Neck Surg 127:84-96. 2002
    ....
  85. ncbi Hearing restoration with auditory brainstem implant in three children with cochlear nerve aplasia
    Vittorio Colletti
    Ear, Nose, and Throat Department, University of Verona, Italy
    Otol Neurotol 23:682-93. 2002
    ..To verify the possibility of auditory habilitation in children with aplasia and hypoplasia of the cochlear nerve by direct electrical stimulation of the cochlear nuclei with an auditory brainstem implant...
  86. ncbi Traditional and emerging indications in cochlear and auditory brainstem implants
    F J Cervera-Paz
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital and Medical School, University of Navarra, Pamplona, Spain
    Rev Laryngol Otol Rhinol (Bord) 126:287-92. 2005
    ..This review will be exemplified with data from the University of Navarra Cochlear Implant Program, currently accounting for more than 500 patients implanted...
  87. ncbi Biocompatibility and healing process of polyester meshes in the brain: in vivo examination in rats
    Ralf Quester
    Center for Neurosurgery, Stereotactic and Functional Neurosurgery Clinic, Faculty of Medicine, University of Cologne, Germany
    Biomaterials 24:711-21. 2003
    ..To analyze the biocompatibility of multifilament polyester (PET) meshes used for the implantation of auditory brainstem implants in a standardized Wistar rat model (n=29)...
  88. ncbi Auditory brainstem implant in a child with severely ossified cochlea
    Mario Sanna
    Gruppo Otologico Piacenza, Rome, Italy
    Laryngoscope 116:1700-3. 2006
    ..The aim of our study is to present a case where brainstem implantation was successfully performed as an alternative to cochlear implantation in a child with bilateral severe ossification of the cochlea...
  89. ncbi [Auditory brainstem implant: indications and results]
    D Bouccara
    Service d ORL, APHP, Hopital Beaujon, Universite Paris VII, 100 Boulevard du General Leclerc, 92110 Clichy, France
    Ann Otolaryngol Chir Cervicofac 124:148-54. 2007
    ..To summarize the indications and evaluate the Auditory Brainstem Implant (ABI) performances in neurofibromatosis type 2 (NF2) and other otologics indications, as postmeningitis ossified cochlea...
  90. ncbi Effect of topically applied basic fibroblast growth factor on injured cochlear nerve
    Tetsuji Sekiya
    Department of Neurosurgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Neurosurgery 52:900-7; discussion 907. 2003
    ..To challenge such a pessimistic view, we investigated whether pharmacological interventions with basic fibroblast growth factor (bFGF) could ameliorate trauma-induced cochlear nerve degeneration...
  91. ncbi Role of CT and MRI in the preoperative evaluation of auditory brainstem implantation in patients with congenital inner ear pathology
    R Cerini
    Istituto di Radiologia, Universita di Verona, Policlinico G B Rossi, Verona, Italy
    Radiol Med 111:978-88. 2006
    ..The purpose of this study was to evaluate the reliability of computed tomography (CT) and magnetic resonance imaging (MRI) in characterising cochlear nerve anomalies in auditory brainstem implant candidates with congenital hearing loss...
  92. ncbi Auditory brainstem implantation to rehabilitate profound hearing loss with totally ossified cochleae induced by pneumococcal meningitis
    Alexis Bozorg Grayeli
    Department of Otolaryngology, Head and Neck Surgery, Hopital Beaujon, Clichy, France
    Audiol Neurootol 12:27-30. 2007
    ..Auditory brainstem implants are an efficient means of auditory rehabilitation and may be considered in selected cases of bilateral profound hearing loss with the impossibility of cochlear implantation...
  93. ncbi Neuroprosthetic hearing with auditory brainstem implants
    J Kuchta
    Department of Neurosurgery, Cologne University Hospital, Germany
    Biomed Tech (Berl) 49:83-7. 2004
    ..The task for the next years is to improve the outcome of ABI further by developing new less invasive operative approaches as well as new hardware and software for the ABI device...
  94. ncbi Hearing rehabilitation in neurofibromatosis type 2 patients: cochlear versus auditory brainstem implantation
    Vincenzo Vincenti
    Department of Otorhinolaryngology, University of Parma, Parma, Italy
    Audiol Neurootol 13:273-80. 2008
    ..We aimed to evaluate and compare the auditory performance of neurofibromatosis type 2 (NF2) patients with bilateral total deafness fitted with cochlear or auditory brainstem implants...
  95. ncbi [Review of audiometric criteria in treatment of neurosensorial deafness with hearing aids and implantable hearing devices]
    Manuel Manrique
    Departamento de Otorrinolaringologia, Clinica Universitaria de Navarra, Universidad de Navarra, Pamplona, Navarra, Espana
    Acta Otorrinolaringol Esp 59:30-8. 2008
    ....
  96. ncbi Cochlear implantation at under 12 months: report on 10 patients
    Vittorio Colletti
    ENT Department, University of Verona, Verona, Italy
    Laryngoscope 115:445-9. 2005
    ..Children aged as little as 12 months are now being implanted in some centers. On the basis of our experience with very young children, we believe that the date of implantation may be further reduced to only 4 to 6 months of age...
  97. ncbi [Brain stem implant can restore hearing. Treatment of deafness in bilateral acoustic neuroma]
    Gunnar Nyberg
    Neurokirurgiska kliniken, Neurodivisionen, Akademiska sjukhuset, Uppsala
    Lakartidningen 104:3553-6. 2007
  98. ncbi Bioengineering solutions for hearing loss and related disorders
    Dawn Burton Koch
    Advanced Bionics Corp, 25129 Rye Canyon Loop, Valencia, CA 91355, USA
    Otolaryngol Clin North Am 38:255-72. 2005
    ..Future technological developments will expand the benefits of current devices and offer new treatments for otologic disorders...
  99. ncbi Electrically evoked hearing perception by functional neurostimulation of the central auditory system
    M Tatagiba
    Department of Neurosurgery, Eberhard Karls University, Tuebingen, Germany
    Acta Neurochir Suppl 93:93-5. 2005
    ..The auditory outcome may be improved by a new generation of microelectrodes capable of penetrating the surface of the brainstem to access more directly the auditory neurons...
  100. ncbi Inferior colliculus responses to multichannel microstimulation of the ventral cochlear nucleus: implications for auditory brain stem implants
    Mohit N Shivdasani
    The Bionic Ear Institute, East Melbourne Victoria, Melbourne, Victoria, Australia
    J Neurophysiol 99:1-13. 2008
    ..These data provide significant implications for auditory brain stem implant electrode placement, current localization, power requirements, and facilitation of information transfer to higher brain centers...
  101. ncbi Auditory brainstem implant (ABI): new frontiers in adults and children
    Vittorio Colletti
    ENT Department, University of Verona, Italy
    Otolaryngol Head Neck Surg 133:126-38. 2005
    ....

Research Grants6

  1. Identification of Novel Drug Targets For Use in Preventing Deafness Caused by NF2
    CRISTINA MARIA FERNANDEZ-VALLE; Fiscal Year: 2013
    ..These studies are initial steps in validating LIMK and/or cofilin as drug targets for development of an effective treatment for NF2 aimed at preserving hearing. ..
  2. SINGLE-CELL MARKING STUDIES OF THE AUDITORY NERVE
    David K Ryugo; Fiscal Year: 2010
    ..Lastly, the new knowledge could contribute to improved treatment strategies for users of bilateral cochlear implants and impact considerations of auditory brainstem implants. ..
  3. Circuit mechanisms for temporal filtering in the auditory thalamus
    ALFRED P KAYE; Fiscal Year: 2012
    ..The project also represents an application of optical control of neural activity in the auditory system, a potentially exciting avenue for future prosthetics research. ..
  4. MICROELECTRODE ARRAYS FOR DEEP BRAIN STIMULATION AND REC
    Douglas McCreery; Fiscal Year: 2002
    ..We will attach multisite silicon substrate recording microelectrode arrays to some of the iridium shafts and these will be chronically implanted into the feline globus pallidus and subthalamic nuclei for up to 180 days. ..
  5. Arrays for deep brain microstimulation and recording
    DOUGLAS BUCHANAN MCCREERY; Fiscal Year: 2010
    ..This technology will improve quality of life for persons afflicted with Parkinson's Disease and other movement disorders. ..
  6. Assessing Auditory Capacity in Hearing-Impaired Children
    Laurie Eisenberg; Fiscal Year: 2007
    ..The results will be analyzed to explain and model auditory perceptual development in terms of multiple contributing variables and their interactions. ..