Genomes and Genes
prostheses and implants
Summary: Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.
Publications385 found, 100 shown here
- Visual perception in a blind subject with a chronic microelectronic retinal prosthesisMark S Humayun
Doheny Retina Institute at the Doheny Eye Institute, University of Southern California, 1450 San Pablo Street Room 3600, Keck School of Medicine, Los Angeles, CA 14627, USA
Vision Res 43:2573-81. 2003..In addition, the subject was able to use a camera to detect the presence or absence of ambient light, to detect motion, and to recognize simple shapes...
- Neuronal ensemble control of prosthetic devices by a human with tetraplegiaLeigh R Hochberg
Department of Neurology, Massachusetts General Hospital, Brigham and Women s Hospital, and Spaulding Rehabilitation Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, USA
Nature 442:164-71. 2006..These early results suggest that NMPs based upon intracortical neuronal ensemble spiking activity could provide a valuable new neurotechnology to restore independence for humans with paralysis...
- Intacs implantation using a femtosecond laser for management of keratoconus: Comparison of 306 cases in different stagesAylin Ertan
Kudret Eye Hospital, Kennedy Caddesi No 71, Kavaklidere, Ankara, Turkey
J Cataract Refract Surg 34:1521-6. 2008..To evaluate the efficacy of intrastromal ring segment (Intacs, Addition Technology, Inc.) implantation and analyze outcomes according to different keratoconus stages...
- Correcting keratoconus with intracorneal ringsJ Colin
Brest University Hospital, Brest, France
J Cataract Refract Surg 26:1117-22. 2000..To evaluate the potential of intrastromal corneal ring technology (Intacs, KeraVision) to correct keratoconus without central corneal scarring...
- A high-performance brain-computer interfaceGopal Santhanam
Department of Electrical Engineering, Stanford University, 330 Serra Mall, 319 Paul G Allen Center for Integrated Systems Annex, Stanford, California 94305 4075, USA
Nature 442:195-8. 2006..These performance results and their implications for system design should substantially increase the clinical viability of BCIs in humans...
- Prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of the ProDisc-L total disc replacement compared with circumferential arthrodesis for the treatment of two-level lumbar degenerative disc disease: resRick Delamarter
The Spine Institute at Saint John s Health Center, 1301 20th Street, Suite 400, Santa Monica, CA 90404, USA
J Bone Joint Surg Am 93:705-15. 2011....
- Long-term results following titanium cranioplasty of large skull defectsMario Cabraja
Department of Neurosurgery, Charite Universitatsmedizin Berlin, Germany
Neurosurg Focus 26:E10. 2009..In this retrospective study of large skull defects, the authors compared computer-assisted design/computer-assisted modeled (CAD/CAM) titanium implants for cranioplasty with other frequently used materials described in literature...
- Improved diagnosis of periprosthetic joint infection by multiplex PCR of sonication fluid from removed implantsYvonne Achermann
Infectious Diseases Service, Department of Internal Medicine, Cantonal Hospital Zug, Baar, Switzerland
J Clin Microbiol 48:1208-14. 2010..With modified primer sets, multiplex PCR has the potential for further improvement of the diagnosis of PJI...
- A prospective, randomized, multicenter Food and Drug Administration investigational device exemptions study of lumbar total disc replacement with the CHARITE artificial disc versus lumbar fusion: part I: evaluation of clinical outcomesScott Blumenthal
Texas Back Institute, Plano, Texas 75093, USA
Spine (Phila Pa 1976) 30:1565-75; discussion E387-91. 2005..A prospective, randomized, multicenter, Food and Drug Administration-regulated Investigational Device Exemption clinical trial...
- Results from the multicenter Boston Type 1 Keratoprosthesis StudyBrian L Zerbe
Albany Medical College, Albany, New York, USA
Ophthalmology 113:1779.e1-7. 2006..To report indications, practices, complications, and outcomes from the first multicenter study on the Boston Type 1 keratoprosthesis...
- Mediation of biomaterial-cell interactions by adsorbed proteins: a reviewCameron J Wilson
Tissue BioRegeneration Domain, Institute of Health and Biomedical Innovation, School of Engineering Systems, Queensland University of Technology, Brisbane, Queensland, Australia
Tissue Eng 11:1-18. 2005..Hence, one of the key issues yet to be resolved is that of the interface composition actually encountered by osteoblasts within the sequence of inflammation and bone regeneration...
- INTACS inserts for treating keratoconus: one-year resultsJ Colin
Bordeaux University Hospital, Hopital Pellegrin, Bordeaux, France
Ophthalmology 108:1409-14. 2001..The corneal steepening and astigmatism associated with keratoconus were reduced, and visual acuity was improved with treatment in almost all eyes...
- Comparison of single-segment and double-segment Intacs for keratoconus and post-LASIK ectasiaMunish Sharma
Boxer Wachler Vision Institute, 465 North Roxbury Drive, Beverly Hills, CA 90210, USA
Am J Ophthalmol 141:891-5. 2006..To evaluate the efficacy of single-segment Intacs and compare with double-segment Intacs in subjects with post-LASIK ectasia and keratoconus...
- The significance of infection related to orthopedic devices and issues of antibiotic resistanceDavide Campoccia
Research Unit on Implant Infections, Rizzoli Orthopedic Institute, Via di Barbiano, 1 10, 40136 Bologna, Italy
Biomaterials 27:2331-9. 2006....
- Intracorneal rings for keratoconus and keratectasiaAylin Ertan
Kudret Eye Hospital, Ankara, Turkey, and the Bordeaux University, Bordeaux, France
J Cataract Refract Surg 33:1303-14. 2007..This article reviews the latest data published or presented at meetings on the correction of keratoconus and keratectasia by intracorneal ring segments...
- Fabrication methods of porous metals for use in orthopaedic applicationsGarrett Ryan
National University of Ireland, Department of Mechanical and Biomedical Engineering, Nun s Island, Galway, Ireland
Biomaterials 27:2651-70. 2006..This review summarises all known methods for fabricating such porous metallic scaffolds...
- Bayesian population decoding of motor cortical activity using a Kalman filterWei Wu
Division of Applied Mathematics, Brown University, Providence, RI 02912, USA
Neural Comput 18:80-118. 2006..Additionally the formulation unifies and extends previous models of neural coding while providing insights into the motor-cortical code...
- Biomaterials in orthopaedicsM Navarro
Biomaterials, Implants and Tissue Engineering, Institute for Bioengineering of Catalonia IBEC, CIBER BBN, 08028 Barcelona, Spain
J R Soc Interface 5:1137-58. 2008..In this review, the evolution of different metals, ceramics and polymers most commonly used in orthopaedic applications is discussed, as well as the different approaches used to fulfil the challenges faced by this medical field...
- Interspinous implants (X Stop, Wallis, Diam) for the treatment of LSS: is there a correlation between radiological parameters and clinical outcome?Rolf Sobottke
Department of Orthopaedic and Trauma Surgery, University of Cologne, Joseph Stelzmann Str 9, 50924, Cologne, Germany
Eur Spine J 18:1494-503. 2009..The interspinous implant offers significant, longlasting symptom control, even if initially significant radiological changes seem to revert toward the initial values ("loss of correction")...
- Intacs in advanced keratoconusRohit Shetty
Cornea and Refractive Surgery Service, Narayana Nethralaya, Postgraduate Institute of Ophthalmology, Bangalore, India
Cornea 27:1022-9. 2008..To evaluate the surgical outcomes of microthin intracorneal ring segment (INTACS) implantation in advanced keratoconus...
- Implant healing in experimental animal models of diabetesNga N Le
Division of Plastic, Reconstructive, Maxillofacial and Oral Surgery, Kenan Plastic Surgery Research Laboratories, Duke University Medical Center, Durham, North Carolina, USA
J Diabetes Sci Technol 5:605-18. 2011....
- Correction of presbyopia with a small aperture corneal inlayGeorge O Waring
Revision Advanced Laser Eye Center, Columbus, Ohio 43240, USA
J Refract Surg 27:842-5. 2011..To assess the efficacy of a small aperture corneal inlay (KAMRA, AcuFocus Inc) to improve near vision in emmetropic presbyopes...
- High surface energy enhances cell response to titanium substrate microstructureG Zhao
Georgia Institute of Technology, Atlanta, GA 30332, USA
J Biomed Mater Res A 74:49-58. 2005..This suggests that increased bone formation observed on modified Ti surfaces in vivo is due in part to stimulatory effects of high surface energy on osteoblasts...
- One-year visual outcomes and patient satisfaction after surgical correction of presbyopia with an intracorneal inlay of a new designAlois K Dexl
University Eye Clinic, Paracelsus Medical University, Salzburg, Austria
J Cataract Refract Surg 38:262-9. 2012..To evaluate the safety and efficacy of the third-generation Kamra corneal inlay (ACI 7000PDT) implanted monocularly in corneal pockets of emmetropic presbyopic patients to improve near and intermediate vision...
- Intracorneal ring segment implantation for the management of keratoconus: safety and efficacyMohammad A Zare
Department of Ophthalmology and Ophthalmic Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
J Cataract Refract Surg 33:1886-91. 2007..To assess the safety and efficacy of intracorneal ring segment (Intacs, Addition Technology, Inc.) implantation in the management of keratoconus...
- Optical modeling of a corneal inlay in real eyes to increase depth of focus: optimum centration and residual defocusJuan Tabernero
Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
J Cataract Refract Surg 38:270-7. 2012..To determine the optimum position to center a small-aperture corneal inlay and the effect of residual defocus in the surgical eye to maximize depth of focus...
- Modified intracorneal ring segment implantations (INTACS) for the management of moderate to advanced keratoconus: efficacy and complicationsA John Kanellopoulos
Department of Ophthalmology, New York University Medical School, New York, New York, USA
Cornea 25:29-33. 2006..To evaluate the safety and efficacy of modified intracorneal ring segment implantation (INTACS) in the management of moderate and advanced keratoconus (KCN)...
- Cemented, cementless, and hybrid prostheses for total hip replacement: cost effectiveness analysisMark Pennington
Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London WC1H 9SH, UK
BMJ 346:f1026. 2013..To compare the cost effectiveness of the three most commonly chosen types of prosthesis for total hip replacement...
- X-stop versus decompressive surgery for lumbar neurogenic intermittent claudication: randomized controlled trial with 2-year follow-upBjörn H Strömqvist
Department of Orthopedics, Clinical Sciences Lund, Lund University, Skane University Hospital, Malmo, Sweden
Spine (Phila Pa 1976) 38:1436-42. 2013..Prospective randomized controlled study...
- The antimicrobial and osteoinductive properties of silver nanoparticle/poly (DL-lactic-co-glycolic acid)-coated stainless steelYi Liu
Shandong Provincial Laboratory of Oral Biomedicine, School and Hospital of Stomatology, Shandong University, Jinan, Shandong 250012, PR China
Biomaterials 33:8745-56. 2012..Our results indicate that SNPSA has simultaneous antimicrobial and osteoinductive properties that make it a promising therapeutic material in orthopedic surgery...
- Infection of orthopedic implants with emphasis on bacterial adhesion process and techniques used in studying bacterial-material interactionsMarta Ribeiro
Instituto de Engenharia Biomedica, Universidade do Porto, Porto, Portugal
Biomatter 2:176-94. 2012....
- Binocular visual simulation of a corneal inlay to increase depth of focusJuan Tabernero
Laboratorio de Optica, Universidad de Murcia, Campus de Espinardo, Murcia, Spain
Invest Ophthalmol Vis Sci 52:5273-7. 2011..To investigate binocular visual acuity and depth of focus when one eye forms images through a typical pupil diameter aperture (4 mm) and the other eye through a small pupil of 1.5-mm diameter...
- Evaluation of the stability of Boston type I keratoprosthesis-donor cornea interface using anterior segment optical coherence tomographyJulian P S Garcia
The New York Eye and Ear Infirmary, New York, USA
Cornea 29:1031-5. 2010..The presence of a gap would raise concerns of a possible pathway for the exchange of extraocular fluid with the anterior chamber...
- Microbial keratitis after intrastromal corneal ring segment implantationM Emilia Mulet
Department of Ophthalmology, Miguel Hernandez University, Alicante, Spain
J Refract Surg 26:364-9. 2010..To evaluate the incidence of acute microbial keratitis after intrastromal corneal ring segment implantation and to investigate whether microbial keratitis is related to the intrastromal corneal ring type or surgical technique...
- Customised fabricated implants after previous failed cranioplastyRaymond C W Goh
Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu Shin Street, Kwei Shan, Taoyuan 333, Taiwan
J Plast Reconstr Aesthet Surg 63:1479-84. 2010..Customised fabricated alloplastic implants provide a safe, accurate and efficient way of restoring normal cranial contours in patients with cranial defects who have had previous failed cranioplasties...
- Outcome of penicillin-susceptible streptococcal prosthetic joint infection treated with debridement and retention of the prosthesisA M Meehan
Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Clin Infect Dis 36:845-9. 2003..For patients who present with a well-fixed prosthesis and a short duration of symptoms, debridement with retention appears to be an effective treatment modality...
- Antibacterial coatings on titanium implantsLingzhou Zhao
School of Stomatology, The Fourth Military Medical University, Xi an 710072, People s Republic of China
J Biomed Mater Res B Appl Biomater 91:470-80. 2009..One important strategy is to render the implant surface antibacterial by impeding the formation of a biofilm. A number of approaches have been proposed for this purpose and they are reviewed in this article...
- Artificial anal sphincter: complications and functional results of a large personal seriesJose M Devesa
Division of Colon and Rectal Surgery, University Hospital Ramon y Cajal, Madrid, Spain
Dis Colon Rectum 45:1154-63. 2002....
- Biofunctionalization of biomaterials for accelerated in situ endothelialization: a reviewAchala de Mel
Centre of Nanotechnology, Biomaterials and Tissue Engineering, UCL Division of Surgery and Interventional Science, University College London, London, United Kingdom
Biomacromolecules 9:2969-79. 2008..EC and EPC interactions with the extracellular matrix continue to be a principal source of inspiration for material biofunctionalization, and therefore, the latest developments in understanding these interactions will be discussed...
- Antibiotic resistance in exopolysaccharide-forming Staphylococcus epidermidis clinical isolates from orthopaedic implant infectionsCarla Renata Arciola
Research Unit on Implant Infections, Rizzoli Orthopaedic Institute, Via Di Barbiano 1 10, 40136 Bologna, Italy
Biomaterials 26:6530-5. 2005..Moreover, multiple resistance to antibiotics was more frequent among exopolysaccharide-forming strains...
- A multicenter, prospective, randomized trial evaluating the X STOP interspinous process decompression system for the treatment of neurogenic intermittent claudication: two-year follow-up resultsJames F Zucherman
St Mary s Hospital, San Francisco, California, USA
Spine (Phila Pa 1976) 30:1351-8. 2005..A randomized, controlled, prospective multicenter trial comparing the outcomes of neurogenic intermittent claudication (NIC) patients treated with the interspinous process decompression system (X STOP) with patients treated nonoperatively...
- A multiaxial force-sensing implantable tibial prosthesisBryan Kirking
Orthopaedic Research Laboratories, Shiley Center for Orthopaedic Research and Education at Scripps Clinic, CA, USA
J Biomech 39:1744-51. 2006..Additional uses are intraoperative measurement of forces to determine soft-tissue balancing and to evaluate the effects of rehabilitation, external bracing, and athletic activities, and activities of daily living...
- Intacs insertion with the femtosecond laser for the management of keratoconus: one-year resultsAylin Ertan
Kudret Eye Hospital, Ankara, Turkey
J Cataract Refract Surg 32:2039-42. 2006..To assess the outcomes of intrastromal ring segment (Intacs, Addition Technology) implantation for keratoconus using the femtosecond laser...
- Microbiologic diagnosis of prosthetic shoulder infection by use of implant sonicationKerryl E Piper
Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, 200 First St S W, Rochester, MN 55905, USA
J Clin Microbiol 47:1878-84. 2009..9%) and sonicate fluid culture (40.9%). All subjects from whom P. acnes was isolated from sonicate fluid were male. We conclude that sonicate fluid culture is useful for the diagnosis of prosthetic shoulder infection...
- Late bacterial keratitis after implantation of intrastromal corneal ring segmentsTristan Bourcier
Quinze Vingts National Center of Ophthalmology, Paris, France
J Cataract Refract Surg 29:407-9. 2003..The infiltrates progressed despite treatment with topical fortified and systemic antibiotics. The Intacs were removed. The keratitis slowly resolved, and the patient recovered a best corrected visual acuity of 20/20...
- Low stiffness porous Ti structures for load-bearing implantsB Vamsi Krishna
W M Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164 2920, USA
Acta Biomater 3:997-1006. 2007..to reduce effective stiffness for load-bearing implants. Young's modulus and 0.2% proof strength of these porous Ti samples having 35-42vol.% porosity are found to be similar to those of human cortical bone...
- Advances in Boston keratoprosthesis: enhancing retention and prevention of infection and inflammationBilal F Khan
Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Boston, MA 02114, USA
Int Ophthalmol Clin 47:61-71. 2007
- Taylored implants for alloplastic cranioplasty--clinical and surgical considerationsB Hoffmann
Neurosurgical Clinic, Clemenshospital Münster, Germany
Acta Neurochir Suppl 93:127-9. 2005..Application of this technique is limited by cost, nonetheless it is recommended for extensive reconstruction of the skull...
- The Otto Aufranc Award: bone augmentation around and within porous implants by local bisphosphonate elutionMichael Tanzer
Department of Surgery, McGill University, Montreal, Quebec, Canada
Clin Orthop Relat Res 441:30-9. 2005..The concept represents a potential tool for restoration of bone stock and enhancement of implant fixation in primary and revision cementless joint arthroplasty surgeries in the face of compromised or deficient bone...
- Computer aided design of large-format prefabricated cranial platesDavid Dean
Department of Neurological Surgery and the Research Institute, University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
J Craniofac Surg 14:819-32. 2003..Therefore, the authors conclude that their new production method provides a better result with less expense than current methods for preoperative or intraoperative fabrication of large-format cranioplasties...
- The potential role of human osteoblasts for periprosthetic osteolysis following exposure to wear particlesKatrin Lochner
Department of Orthopaedics, University of Rostock, D 18057 Rostock, Germany
Int J Mol Med 28:1055-63. 2011..Among the reference particles, which caused less altered reactions in the metabolism of osteoblasts in general, ZrO2 can be assumed as the material with the smallest cell biological effects...
- BMP-2 liberated from biomimetic implant coatings induces and sustains direct ossification in an ectopic rat modelY Liu
Biomaterials Research Group, Twente University, Enschede, The Netherlands
Bone 36:745-57. 2005..Using a rat model, we evaluated the kinetics and histomorphometry of ectopic bone formation in association with biomimetic implant coatings containing BMP-2...
- Silver-coated megaendoprostheses in a rabbit model--an analysis of the infection rate and toxicological side effectsGeorg Gosheger
Department of Orthopedics, University of Muenster, Albert Schweitzer Str 33, 48149 Muenster, Germany
Biomaterials 25:5547-56. 2004....
- Staphylococcus aureus bacteremia in patients with prosthetic devices: costs and outcomesVivian H Chu
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Am J Med 118:1416. 2005..aureus bacteremia on patients with prosthetic devices. This investigation sought to define the clinical outcome, health care resource use, and infection-associated costs of S. aureus bacteremia in patients with prostheses...
- Overcoming artifacts from metallic orthopedic implants at high-field-strength MR imaging and multi-detector CTMi Jung Lee
Department of Diagnostic Radiology and Research Institute of Radiological Science and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 134 Sincheon Dong Seodaemun Gu, Seoul 120 752, Republic of Korea
Radiographics 27:791-803. 2007..A comparison of images obtained with different hardware and different acquisition and reconstruction parameters facilitates an understanding of methods for reducing or overcoming artifacts related to metallic implants...
- Boston keratoprosthesis outcomes and complicationsHall F Chew
Cornea Service, Wills Eye Institute, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
Cornea 28:989-96. 2009..To evaluate the outcomes of the Boston Keratoprosthesis (KPro) at our institution...
- Vestibular prostheses: the engineering and biomedical issuesC Wall
Harvard Medical School, Department of Otology and Laryngology, Boston, MA 02114, USA
J Vestib Res 12:95-113. 2002..In this "white paper", we consider these issues in the context of prototype baseline prosthetic devices...
- Local alendronate increases fixation of implants inserted with bone compaction: 12-week canine studyThomas Jakobsen
Orthopaedic Research Laboratory, Department of Orthopaedics, Aarhus University Hospital, Norrebrogade 44, Bldg 1A, DK 8000 Aarhus C, Denmark
J Orthop Res 25:432-41. 2007..3-fold). This study indicates that local alendronate treatment can increase early implant osseointegration and biomechanical fixation of implants inserted by use of bone compaction. Long term effects remain unknown...
- Direct cortical control of 3D neuroprosthetic devicesDawn M Taylor
Department of Bioengineering, Arizona State University, Tempe, AZ 85287 6006, USA
Science 296:1829-32. 2002..By using control algorithms that track these changes, subjects made long sequences of 3D movements using far fewer cortical units than expected. Daily practice improved movement accuracy and the directional tuning of these units...
- Nanostructured materials for inhibition of bacterial adhesion in orthopedic implants: a minireviewL Montanaro
Research Unit on Implant Infections, Rizzoli Orthopedic Institute, Bologna and Department of Experimental Pathology of the University of Bologna, Bologna Italy
Int J Artif Organs 31:771-6. 2008..This minireview discusses studies on nanophase materials as bone implants, focusing on the effect of these materials in inhibiting bacterial adhesion for the prevention of implant infections...
- Biofilm formation and composition on different implant materials in vivoA Al-Ahmad
Department of Operative Dentistry and Periodontology, Albert Ludwigs University, 79106 Freiburg, Germany
J Biomed Mater Res B Appl Biomater 95:101-9. 2010..were also detected. No significant differences in biofilm composition on the implant surfaces could be observed. In total, the influence of roughness and material on biofilm formation was compensated by biofilm maturation...
- Functional electrical stimulation for neuromuscular applicationsP Hunter Peckham
Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA
Annu Rev Biomed Eng 7:327-60. 2005....
- Porous tantalum structures for bone implants: fabrication, mechanical and in vitro biological propertiesVamsi Krishna Balla
WM Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164 2920, USA
Acta Biomater 6:3349-59. 2010..Our results show that these laser-processed porous Ta structures can find numerous applications, particularly among older patients, for metallic implants because of their excellent bioactivity...
- Intrastromal corneal ring segment SK implantation for moderate to severe keratoconusWiwan Sansanayudh
Department of Ophthalmology, Toronto Western Hospital, University of Toronto, Ontario, Canada
J Cataract Refract Surg 36:110-3. 2010..To report the efficacy and safety of intrastromal corneal ring segment (ICRS) implantation using a femtosecond laser in the management of advanced keratoconus...
- Visual outcomes and safety of a refractive corneal inlay for presbyopia using femtosecond laserAliki N Limnopoulou
Department of Opthalmology, Vardinoyannion Eye Institute of Crete, Crete, Greece
J Refract Surg 29:12-8. 2013..To evaluate the outcomes and safety of a refractive inlay (Flexivue Micro-Lens, Presbia Coöperatief U.A.) for the corneal compensation of presbyopia...
- Influence of feedback parameters on performance of a vibrotactile balance prosthesisAdam D Goodworth
Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR 97239, USA
IEEE Trans Neural Syst Rehabil Eng 17:397-408. 2009..6 Hz. Finally, we created a postural model that accounted for the experimental results and gave insight into how vibrotactile information was incorporated into the postural control system...
- Intrastromal corneal ring segments for advanced keratoconus and cases with high keratometric asymmetryMohammad I Khan
Singleton Hospital Abertawe Bro Morgannwg University NHS Trust, Swansea, United Kingdom
J Cataract Refract Surg 38:129-36. 2012..To report the safety and efficacy of intrastromal corneal ring segment (ICRS) implantation to manage keratoconus...
- Short-term cell death and inflammation after intracorneal inlay implantation in rabbitsMarcony R Santhiago
The Cole Eye Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
J Refract Surg 28:144-9. 2012..To investigate the cell death and inflammatory response to insertion of the KAMRA inlay (AcuFocus Inc) for presbyopia...
- Classification of osseointegrated implant surfaces: materials, chemistry and topographyDavid M Dohan Ehrenfest
Department of Biomaterials, Institute for Clinical Sciences, the Sahlgrenska Academy at University of Gothenburg, Sweden
Trends Biotechnol 28:198-206. 2010..This standardized classification system will allow to clarify unambiguously the identity of any given osseointegrated surface and help to identify the biological outcomes of each surface characteristic...
- One-year safety and efficacy results of a hydrogel inlay to improve near vision in patients with emmetropic presbyopiaEnrique Barragan Garza
Laser Ocular hidalgo, Nuevo Leone, Mexico
J Refract Surg 29:166-72. 2013..To conduct a feasibility study of the safety and efficacy of a corneal contouring inlay as a treatment for emmetropic presbyopia...
- Effect of age on outcomes in patients with keratoconus treated by Intacs using a femtosecond laserAylin Ertan
Kudret Eye Hospital, Ankara, Turkey
J Refract Surg 24:690-5. 2008..To compare the response to Intacs treatment in different age groups of patients with keratoconus...
- Effectiveness of interspinous implant surgery in patients with intermittent neurogenic claudication: a systematic review and meta-analysisWouter A Moojen
Department of Neurosurgery, Leiden University Medical Center, Albinusdreef 2, 2300 RC, Leiden, The Netherlands
Eur Spine J 20:1596-606. 2011..The main objective of this review was to perform a meta-analysis of all systematic reviews, randomized clinical trials and prospective cohort series to quantify the effectiveness of IPDs and to evaluate the potential side-effects...
- Corneal aberrometric and refractive performance of 2 intrastromal corneal ring segment models in early and moderate ectatic diseaseDavid P Pinero
Vissum Corporation Instituto Oftalmologico de Alicante, Departamento de Optica, Universidad de Alicante, Alicante, Spain
J Cataract Refract Surg 36:102-9. 2010..To evaluate and compare visual, refractive, and corneal aberrometric outcomes after implantation of 2 types of intrastromal corneal ring segments (ICRS) in eyes with early to moderate ectatic disease...
- Mechanical biocompatibilities of titanium alloys for biomedical applicationsMitsuo Niinomi
Department of Biomaterial Science, Institute for Materials Research, Tohoku University, 2 1 1, Katahira, Aoba ku, Sendai, 980 8577, Japan
J Mech Behav Biomed Mater 1:30-42. 2008....
- Intrastromal corneal ring segment implantation for the treatment of keratoconusAnl Kubaloglu
Dr Lutfi Kirdar Kartal Training and Research Hospital, 2nd Eye Clinic, Istanbul, Turkey
Cornea 30:11-7. 2011..To evaluate the safety and efficacy of intrastromal corneal ring segment implantation using both mechanical and femtosecond-assisted tunnel creation for the treatment of patients with keratoconus...
- Intracorneal ring segments for keratoconus correction: long-term follow-upJorge L Alio
Department of Cornea and Refractive Surgery, Instituto Oftalmologico de Alicante, VISSUM, Spain
J Cataract Refract Surg 32:978-85. 2006..To evaluate long-term results and stability of intracorneal ring segment (Intacs) implantation for keratoconus correction...
- Intracorneal rings to correct corneal ectasia after laser in situ keratomileusisJorge Alio
Refractive Surgery and Cornea Unit, Alicante Institute of Ophthalmology, and Miguel Hernández University School of Medicine, Alicante, Spain
J Cataract Refract Surg 28:1568-74. 2002..To evaluate the potential of using intrastromal corneal ring technology (Intacs, KeraVision) to correct posterior ectasia after laser in situ keratomileusis (LASIK) for myopia...
- Pathogenesis of infections due to coagulase-negative staphylococciChristof von Eiff
Institute of Medical Microbiology, University of Münster Hospital and Clinics, Munster, Germany
Lancet Infect Dis 2:677-85. 2002....
- Multiwaveguide implantable probe for light delivery to sets of distributed brain targetsAnthony N Zorzos
MIT Media Lab Synthetic Neurobiology Group, Department of Brain and Cognitive Sciences, and MIT McGovern Institute, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
Opt Lett 35:4133-5. 2010..1 ± 1 dB/cm using the outscattering method and 3.2 ± 0.4 dB/cm using the cutback method; corner mirror loss, 1.5 ± 0.4 dB); a waveguide coupled, for example, to a 5 mW source will deliver over 1.5 mW to a target at a depth of 1 cm...
- Electric crosstalk impairs spatial resolution of multi-electrode arrays in retinal implantsR G H Wilke
Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW, 2052 Australia
J Neural Eng 8:046016. 2011..However, if the implantation site is further from the target cells, as is the case in suprachoroidal approaches, hexagonally guarded electrode return configurations can convey higher spatial resolution...
- An overview of nano-polymers for orthopedic applicationsGanesan Balasundaram
Divisions of Engineering and Orthopaedics, Brown University, Box D, 224 Barus and Holley, 182 Hope Street, Providence, RI 02912, USA
Macromol Biosci 7:635-42. 2007..Nanotechnology (or the use of nanomaterials) is providing a wide range of new materials to improve the current short lifetimes of orthopedic implants...
- Effect of the cord pretension of the Dynesys dynamic stabilisation system on the biomechanics of the lumbar spine: a finite element analysisChien Lin Liu
Department of Orthopaedic Surgery, Taipei Veterans General Hospital, Taipei, Taiwan
Eur Spine J 20:1850-8. 2011..In addition, use of a 300 N cord pretension causes a much higher stiffness at the implanted level when compared with the intact lumbar spine...
- Clinical features and prognosis of Boston type I keratoprosthesis-associated corneal meltCanan Asli Utine
Ocular Surface Disease and Dry Eye Clinic, Cornea and External Disease Service, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 9238, USA
Ocul Immunol Inflamm 19:413-8. 2011..To describe the clinical features and outcomes of corneal melt associated with Boston type I keratoprosthesis (KPro) implantation...
- Expanding application of the Boston type I keratoprosthesis due to advances in design and improved post-operative therapeutic strategiesAisha S Traish
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
Semin Ophthalmol 25:239-43. 2010..To evaluate how the advances in design of the Boston type I keratoprosthesis and in the treatment strategies to conquer the post operative complications have expanded the indications and application of this technology...
- Short-term visual outcomes of Boston type 1 keratoprosthesis implantationKaren Dunlap
Ocular Surface Diseases and Dry Eye Clinic, The Wilmer Eye Institute, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287 9238, USA
Ophthalmology 117:687-92. 2010..To report the short-term visual outcomes after keratoprosthesis implantation...
- In vivo gene expression in response to anodically oxidized versus machined titanium implantsOmar Omar
Department of Biomaterials, Sahlgrenska Academy at University of Gothenburg, Sweden
J Biomed Mater Res A 92:1552-66. 2010....
- Occult spinous process fractures associated with interspinous process spacersDavid H Kim
Tufts University School of Medicine, 125 Parker Hill Ave, Boston, MA 02120, USA
Spine (Phila Pa 1976) 36:E1080-5. 2011..Prospective observational study...
- Enhanced functions of osteoblasts on nanometer diameter carbon fibersKathy L Elias
Department of Biomedical Engineering, Purdue University, West Lafayette, IN 47907 1296, USA
Biomaterials 23:3279-87. 2002....
- Lumbar interspinous spacers: a systematic review of clinical and biomechanical evidenceSyed M R Kabir
National Hospital for Neurology and Neurosurgery, London, United Kingdom
Spine (Phila Pa 1976) 35:E1499-506. 2010..Systematic review...
- Expanding indications for the Boston keratoprosthesisKathryn A Colby
Cornea and Refractive Surgery, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
Curr Opin Ophthalmol 22:267-73. 2011..To review emerging indications for the Boston keratoprosthesis (KPro) and to discuss current research underway to improve clinical outcomes...
- Boston type 1 keratoprosthesis for severe blinding vernal keratoconjunctivitis and Mooren's ulcerSayan Basu
Cornea and Anterior Segment Service, LV Prasad Eye Institute, Kallam Anji Reddy Campus, Banjara Hills Road No 2, Hyderabad, India
Int Ophthalmol 31:219-22. 2011..To our knowledge this is the first report of successful Boston keratoprosthesis implantation for these two unusual indications...
- The role of soft contact lenses as an adjunct to the Boston keratoprosthesisMona Harissi-Dagher
Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
Int Ophthalmol Clin 48:43-51. 2008
- Mechanical evaluation of porous titanium (Ti6Al4V) structures with electron beam melting (EBM)Jayanthi Parthasarathy
School of Industrial Engineering, University of Oklahoma, Norman, OK 73019, USA
J Mech Behav Biomed Mater 3:249-59. 2010....
- The Boston keratoprosthesis in Stevens-Johnson syndromeRony R Sayegh
Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
Am J Ophthalmol 145:438-44. 2008..To evaluate the use of the Boston keratoprosthesis (KPro) in patients with Stevens-Johnson syndrome (SJS)...
- The clinical impact of incomplete left atrial appendage closure with the Watchman Device in patients with atrial fibrillation: a PROTECT AF (Percutaneous Closure of the Left Atrial Appendage Versus Warfarin Therapy for Prevention of Stroke in Patients WitJuan F Viles-Gonzalez
Mount Sinai School of Medicine, New York City, New York, USA
J Am Coll Cardiol 59:923-9. 2012..Plymouth, Minnesota)...
- Quality of life of lumbar stenosis-treated patients in whom the X STOP interspinous device was implantedKen Y Hsu
Department of Orthopaedics, St Mary s Medical Center, St Mary s Spine Center, San Francisco, California 94117, USA
J Neurosurg Spine 5:500-7. 2006....
- One-year results of X Stop interspinous implant for the treatment of lumbar spinal stenosisManal Siddiqui
Department of Orthopaedics, Woodend Hospital, Aberdeen, Scotland, UK
Spine (Phila Pa 1976) 32:1345-8. 2007..Prospective observational study...
- Two-year results of interspinous spacer (X-Stop) implantation in 175 patients with neurologic intermittent claudication due to lumbar spinal stenosisJohannes Kuchta
Department of Neurosurgery, MediaParc Clinic, Cologne, Germany
Eur Spine J 18:823-9. 2009..Functional (upright-) MRI examinations were able to demonstrate the positional-dependent stenosis. If available, fMRI represents the most helpful radiologic examination in assessing the outcome of interspinous spacer implantation...
- Cyclic loads do not compromise functionality of the interspinous spacer or cause damage to the spinal segment: an in vitro analysisAmanesh Goyal
Engineering Center for Orthopaedic Research Excellence E CORE, Departments of Bioengineering and Orthopaedic Surgery, Colleges of Engineering and Medicine, University of Toledo, Toledo, Ohio 43606, USA
J Long Term Eff Med Implants 18:289-302. 2008..A biomechanical study to evaluate the effects of interspinous spacer under cyclic complex loading...
- Aperius PercLID stand alone interspinous system for the treatment of degenerative lumbar stenosis: experience on 152 casesPiervittorio Nardi
Neurosurgical Unit, Policlinico Casilino, Rome, Italy
J Spinal Disord Tech 23:203-7. 2010..This study is a retrospective clinical investigation of a new interspinous device implanted via a totally percutaneous technique involving 152 consecutive patients...
- Pore throat size and connectivity determine bone and tissue ingrowth into porous implants: three-dimensional micro-CT based structural analyses of porous bioactive titanium implantsBungo Otsuki
Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Shogoin, Kyoto 606 8507, Japan
Biomaterials 27:5892-900. 2006..Data obtained suggest that this sort of novel analysis is useful for evaluating bone and tissue ingrowth into porous biomaterials...
- INDUCTION OF DE NOVO DENTAL PAPILLAE FROM YOUNG RODENTMina Mina; Fiscal Year: 2001..As a result tooth loss is currently being treated by a variety of traditional clinical therapies using prostheses and implants. However, these devices are incapable of replacing all the junctions of the original tooth, often fail ..
- Processing of Materials for Improved BiocompatibilityMichael Matthews; Fiscal Year: 2004..will conduct basic research to improve biocompatibility of materials used in biomedical devices such as prostheses and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing ..
- Data Communication with Implantable Micro DevicesMingui Sun; Fiscal Year: 2002..We will implant this device within the brain of laboratory dogs and evaluate its performance. ..
- FGF-Silyl-Heparin Cerebral Aneurysm CoilsPAUL ZAMORA; Fiscal Year: 2002..The Phase I studies will develop the coated coils and perform initial animal evaluations. ..
- Prostate Edema in Permanent Interstitial BrachytherapyZhe Chen; Fiscal Year: 2010..The primary objective of this project is to develop a new method to consider the effects of edema in radiation dosimetry and treatment planning so that the efficacy of this therapy can be optimized for each patient. ..
- Motion Sensor Array for Vestibular-deficient IndividualsConrad Wall; Fiscal Year: 2005....
- PARALLEL INFORMATION PROCESSING OF THE VISUAL SYSTEMPeter Schiller; Fiscal Year: 2002..The proposed work has important clinical relevance as it will serve characterize the functions of various visual cortical areas. ..
- Thromboresistant vascular grafts:heparin-peptidomimeticsPAUL ZAMORA; Fiscal Year: 2004..abstract_text> ..
- The Role of Areas V1 and V2 in Target SelectionPeter Schiller; Fiscal Year: 2008..abstract_text> ..
- NEURAL CONTROL OF VISUALLY GUIDED EYE MOVEMENTSPeter Schiller; Fiscal Year: 2007..abstract_text> ..
- Osteolysis and Implant Wear: Biological, Biomedical Engineering, and Surgical PriStuart Goodman; Fiscal Year: 2007..unreadable] [unreadable] [unreadable] [unreadable]..
- Infusion of Particles at Implant interfecesStuart Goodman; Fiscal Year: 2006..abstract_text> ..
- Development of semicircular canal prostheses for studies of vestibular plasticityDANIEL MERFELD; Fiscal Year: 2009..abstract_text> ..
- Novel vision tests: data analysis from a RP Lutein trialGislin Dagnelie; Fiscal Year: 2004....
- Adaptation to controlled vestibular stimulationDANIEL MERFELD; Fiscal Year: 2005..All of these proposed specific aims will be investigated by measuring changes in the vestibulo-ocular responses induced by changes in chronic, patterned, electrical stimulation of the peripheral vestibular system. ..
- Calibration Tools For PC-Based Vision EnhancementGislin Dagnelie; Fiscal Year: 2008..Project Description Page 7 ..
- Bioreactivity Markers in Total Hip ReplacmentsNadim Hallab; Fiscal Year: 2004..Additionally, variable immunologic responses induced by implant degradation products (i.e. lymphocyte response to metal ions and monocyte/macrophage response to particulate debris) will be correlated with the development of osteolysis ..
- INJECTABLE SENSORS FOR CONTROL OF FESGerald Loeb; Fiscal Year: 2002....
- BION Treatment of Neuromuscular DysfunctionGerald Loeb; Fiscal Year: 2002..abstract_text> ..
- Bladder and Sphincter Control after Spinal Cord InjuryChangfeng Tai; Fiscal Year: 2008..abstract_text> ..
- Physiological Role of ADAMTS-7B in ArthritisChuanju Liu; Fiscal Year: 2007..unreadable] [unreadable] [unreadable] [unreadable]..
- Coding of action by motor & premotor cortical ensemblesNicholas Hatsopoulos; Fiscal Year: 2008..abstract_text> ..
- INFECTION MECHANISMS WITH CARDIOVASCULAR PROSTHESESJAMES MORLEY ANDERSON; Fiscal Year: 2010..A fibrinogen-based peptide sequence based on fibrinogen/Fbe (S. epidermidis) will be used as a blocking ligand to investigate adhesion blocking mechanisms to prevent bacterial aggregation and biofilm formation. ..
- LYMPHOCYTE/MACROPHAGE INTERACTIONS ON BIOMATERIALSJames Anderson; Fiscal Year: 2001..Results from our combined studies will lead to a greater appreciation of these complex cell/material interactions and novel design criteria for new biomaterials and tissue-engineered surfaces. ..
- THE ROLE OF p204 IN OSTEOGENESISChuanju Liu; Fiscal Year: 2007..A greater understanding of the process of how bone is generated can lead to new therapies which can help stem or reverse the course of these diseases. [unreadable] [unreadable] [unreadable]..
- Conference Support: The 13th International Drug Delivery SymposiumDavid Grainger; Fiscal Year: 2007..Support is requested both for selected speaker participation costs and 3 junior scientist poster travel awards. [unreadable] [unreadable] [unreadable]..
- A Novel Waveform for Electrical Nerve Conduction BlockKevin L Kilgore; Fiscal Year: 2010..This research will provide a significant tool in our ongoing efforts to reduce disability and improve quality of life. ..
- INFECTION MECHANISMS WITH CARDIOVASCULAR PROSTHESESJames Anderson; Fiscal Year: 2001..The biomaterial infection model in rats will be used to test the validity of the in vitro models, as well as the efficacy of the biomimetic coatings ..
- VESTIBULAR INFLUENCES ON SPATIAL ORIENTATIONRichard Lewis; Fiscal Year: 2008..abstract_text> ..
- NEUROLOGIC RECOVERY WITH ROBOTIC AIDSNeville Hogan; Fiscal Year: 2001..Should the hypotheses be falsified, it is expected that this systematic approach combined with the quality of robot-based measurements will contribute to the scientific foundations of neurologic rehabilitation. ..
- Racial Variations in Optic Nerve Head Structure and BiomechanicsJ CRAWFORD contact DOWNS; Fiscal Year: 2011....
- 3D Reconstruction of Optic Nerve HeadsJ Downs; Fiscal Year: 2008..Using these 3D reconstructions of the ONH and principles of biomechanical engineering, we can model the mechanical and vascular effects of elevated IOP in glaucoma. [unreadable] [unreadable] [unreadable]..
- Reduction and Telemetry of Neural Data for an Implantable Data Acquisition SystemMICHAEL RIZK; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- BioMEMS Model of Glomerular FunctionWILLIAM FISSELL; Fiscal Year: 2008..Third, HP and s will be measured for the NM-PBM membrane. Fourth, data from (1-3) will be compared with existing predictive models of glomerular function. ..
- Modeling Sensory Integration and Attention in Postural Control of Older AdultsPatrick Loughlin; Fiscal Year: 2009..Our research will provide new insights into the interaction of balance and attention through cortical brain imaging while subjects perform balance and attention tasks simultaneously. ..
- MORPHOPHYSIOLOGY OF PRE-NUCLEAR OCULOMOTOR NEURONSSTEPHEN HIGHSTEIN; Fiscal Year: 2008..abstract_text> ..
- AVS Biomaterials Interface Division Technical Program SupportDavid Grainger; Fiscal Year: 2006..A number of relevant leading scientists and engineers from companies working in these technology areas are also recruited to participate using the new "Commercial Challenge" podium opportunity. [unreadable] [unreadable] [unreadable]..
- Electrical Stimulation of the Bilaterally Paralyzed Larynx Paced with RespirationDavid L Zealear; Fiscal Year: 2010..This new, more dynamic approach to treatment could restore normal ventilation through the mouth without alteration of voice or swallowing, and return the patient to a physically active lifestyle. ..
- Dental Implant Science & Tech Transfer Satellite MeetingJack Lemons; Fiscal Year: 2004..Both organizations, IRG and WCOI-6 have approved the collaborations. Experience has been that 400 or more implant dentists attend the WCOI-6 and i00 or more researchers attend the IRG satellite sessions. ..
- BioMEMS Materials for Renal Tissue EngineeringWILLIAM FISSELL; Fiscal Year: 2004..Failure of RPTCs to grow on these substrates despite a variety of suface modifications would be extremely important, as it would indicate a need for new materials in bioengineering. ..
- Novel Biodegradable Polymers for Tissue EngineeringCato Laurencin; Fiscal Year: 2004..It is anticipated that at the completion of this project, a viable alternative to existing bone repair materials may be established. ..
- A Novel Waveform for Electrical Nerve Conduction BlockKevin Kilgore; Fiscal Year: 2002..The initial intended human application will be to alleviate pain in individuals with neuromas secondary to limb amputation. ..
- A new allograft that promotes long-term, infection-free skeletal repairNOREEN J contact HICKOK; Fiscal Year: 2010....
- CRANIOFACIAL DEVELOPMENT: METABOLIC CONTROL OF APOPTOSISIrving Shapiro; Fiscal Year: 2003..Taken together, these studies should highlight the molecular basis of bone cell apoptosis, a phenomenon that is now considered critical for bone growth and skeletal remodeling. ..
- EXON-SPECIFIC FIBRONECTIN ISOFORMS AND CHONDROGENESISNOREEN HICKOK; Fiscal Year: 2003..abstract_text> ..
- MOTOR RECOVERY AND MOTOR LEARNING IN STROKE PATIENTSNeville Hogan; Fiscal Year: 2003..In the case of alternative outcomes it is expected that this systematic approach combined with the quality of robot-based measurements will contribute to a scientific foundation for neurologic rehabilitation. ..
- BIOMEDICAL POLYMERS--CELL ADHESION AND CYTOKINESJames Anderson; Fiscal Year: 2006....
- NEW METHOD TO IDENTIFY UNILATERAL VESTIBULAR DYSFUNCTIONRobert Peterka; Fiscal Year: 2002..Experimental results from subjects with different levels of partial unilateral vestibular loss will determine the effectiveness and reliability of the proposed new rotation test. ..
- Knee Implant Wear Evaluation-An Integrated ApproachTimothy Wright; Fiscal Year: 2005..abstract_text> ..
- Analyses of InSitu and Explanted Surgical Implant DevicesJack Lemons; Fiscal Year: 2009..abstract_text> ..
- Development of a Spinal Intervertebral Disc ProsthesisGLENN BUTTERMANN; Fiscal Year: 2003..The objective of Phase I is to demonstrate that the device restores normal spine biomechanics (range of motion and stiffness) and is durable in fatigue testing. ..
- SURFACE INFLUENCES ON CELL SIGNALING AND PROLIFERATIONDavid Grainger; Fiscal Year: 2002....
- Engineering FGF-1 for Increased AngiogenicityEric Brey; Fiscal Year: 2005..The two most angiogenic growth factors will then be assessed for their ability to promote angiogenesis and increase blood flow in a diabetic mouse model of critical limb ischemia. ..
- Natural History of POP-- A Prospective Cohort StudyIngrid Nygaard; Fiscal Year: 2005..The national cost burden is large. This project will provide fundamental data to guide future decisions about intervention threshold, preventative measures, and risk factor modification. ..
- TIME VARYING CHARACTERISTICS OF HUMAN POSTURAL SWAYPatrick Loughlin; Fiscal Year: 2002..An objective of the research is to improve the evaluation and rehabilitation of individuals with balance disorders. ..
- HIGH RESOLUTION ECHOCARDIOGRAPHY SYSTEMMichael Zile; Fiscal Year: 2001..This will foster interdisciplinary investigation, support NIH-funded investigators and trainees, and enhance the competitiveness of MUSC investigators. ..
- A Novel Polymeric Trileaflet Heart Valve ProsthesisSCOTT CORBETT; Fiscal Year: 2008..valves that improves upon the shortcomings of existing replacement valves, reduces the cost burden on the health care system and improves the survival rate of patients with heart valve prostheses [unreadable] [unreadable] [unreadable]..
- GAP JUNCTIONAL COMMUNICATIONS IN WOUND HEALINGH Ehrlich; Fiscal Year: 2009..abstract_text> ..
- Modeling Mass Transfer to Active Implants for DiabetesDavid Gough; Fiscal Year: 2009..This project will examine the permeability of tissues surrounding implanted devices to assess substrate supply to the implant. This information may accelerate implementation of these therapies. ..
- Validation of Long-Term Glucose Sensor in TissuesDavid Gough; Fiscal Year: 2007..This project will further validate an implantable glucose sensor that will provide a basis for reliable detection of hypoglycemia and automatic insulin administration. [unreadable] [unreadable] [unreadable]..
- An Automated System to Monitor Medical Device SafetyFrederic Resnic; Fiscal Year: 2009..This approach can be readily extended to monitor the safety of technologies outside of interventional cardiology as outcomes data repositories become available. ..
- Development of a Multi-phased Scaffold for Soft Tissue to Bone IntegrationHelen Lu; Fiscal Year: 2006..abstract_text> ..
- ACTION - A CHF Trial Investigating Outcomes of ExerciseSteven Keteyian; Fiscal Year: 2007..The trial will take place over 5 years with an initial 6 months for planning, training, and implementation; 3 years of enrollment; 1 year of follow-up; and 6 months for close out, analysis, and presentation. ..
- INFRASTRUCTURE OF BIOENGINEERING DEVELOPMENTDavid Gough; Fiscal Year: 2002..This is necessary to develop biomedical engineering at UCSD to its full potential and to provide a model of bioengineering education and research for the nation. ..
- GNE 2007: Global NeuroEngineering 2007Miguel Nicolelis; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Corticofugal Modulation of Tactile Sensory ProcessingMiguel Nicolelis; Fiscal Year: 2005..abstract_text> ..
- Polymer/Ceramic Composites for Tissue EngineeringCato Laurencin; Fiscal Year: 2009..Specific Aim 3: Evaluation of the biological performance of novel 3-D composite matrices using in vivo techniques. ..
- REHABILITATION OF THE PARALYZED LARYNXDavid Zealear; Fiscal Year: 2006..With respect to the head and neck, FES could be employed initially to reanimate the unilaterally paralyzed face, larynx and pharynx, and in the process, direct natural reinnervation of these structures. ..
- Method for In-Vivo Assessment of Neuronal DysfunctionMiguel Nicolelis; Fiscal Year: 2007....
- An Ultrasonic Neural StimulatorBRUCE TOWE; Fiscal Year: 2002..This market is currently served with conventional electrostimulators by large medical device companies like Medtronic, Guidant, and others. ..