prostheses and implants

Summary

Summary: Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.

Top Publications

  1. ncbi Neuronal ensemble control of prosthetic devices by a human with tetraplegia
    Leigh R Hochberg
    Department of Neurology, Massachusetts General Hospital, Brigham and Women s Hospital, and Spaulding Rehabilitation Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, USA
    Nature 442:164-71. 2006
  2. ncbi A high-performance brain-computer interface
    Gopal Santhanam
    Department of Electrical Engineering, Stanford University, 330 Serra Mall, 319 Paul G Allen Center for Integrated Systems Annex, Stanford, California 94305 4075, USA
    Nature 442:195-8. 2006
  3. ncbi High surface energy enhances cell response to titanium substrate microstructure
    G Zhao
    Georgia Institute of Technology, Atlanta, GA 30332, USA
    J Biomed Mater Res A 74:49-58. 2005
  4. ncbi A prospective, randomized, multicenter Food and Drug Administration investigational device exemptions study of lumbar total disc replacement with the CHARITE artificial disc versus lumbar fusion: part I: evaluation of clinical outcomes
    Scott Blumenthal
    Texas Back Institute, Plano, Texas 75093, USA
    Spine (Phila Pa 1976) 30:1565-75; discussion E387-91. 2005
  5. ncbi Results from the multicenter Boston Type 1 Keratoprosthesis Study
    Brian L Zerbe
    Albany Medical College, Albany, New York, USA
    Ophthalmology 113:1779.e1-7. 2006
  6. ncbi Fabrication methods of porous metals for use in orthopaedic applications
    Garrett Ryan
    National University of Ireland, Department of Mechanical and Biomedical Engineering, Nun s Island, Galway, Ireland
    Biomaterials 27:2651-70. 2006
  7. pmc Interspinous implants (X Stop, Wallis, Diam) for the treatment of LSS: is there a correlation between radiological parameters and clinical outcome?
    Rolf Sobottke
    Department of Orthopaedic and Trauma Surgery, University of Cologne, Joseph Stelzmann Str 9, 50924, Cologne, Germany
    Eur Spine J 18:1494-503. 2009
  8. doi Evaluation of the stability of Boston type I keratoprosthesis-donor cornea interface using anterior segment optical coherence tomography
    Julian P S Garcia
    The New York Eye and Ear Infirmary, New York, USA
    Cornea 29:1031-5. 2010
  9. ncbi Microbial keratitis after intrastromal corneal ring segment implantation
    M Emilia Mulet
    Department of Ophthalmology, Miguel Hernandez University, Alicante, Spain
    J Refract Surg 26:364-9. 2010
  10. doi Long-term results following titanium cranioplasty of large skull defects
    Mario Cabraja
    Department of Neurosurgery, Charite Universitatsmedizin Berlin, Germany
    Neurosurg Focus 26:E10. 2009

Detail Information

Publications335 found, 100 shown here

  1. ncbi Neuronal ensemble control of prosthetic devices by a human with tetraplegia
    Leigh R Hochberg
    Department of Neurology, Massachusetts General Hospital, Brigham and Women s Hospital, and Spaulding Rehabilitation Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, USA
    Nature 442:164-71. 2006
    ..These early results suggest that NMPs based upon intracortical neuronal ensemble spiking activity could provide a valuable new neurotechnology to restore independence for humans with paralysis...
  2. ncbi A high-performance brain-computer interface
    Gopal Santhanam
    Department of Electrical Engineering, Stanford University, 330 Serra Mall, 319 Paul G Allen Center for Integrated Systems Annex, Stanford, California 94305 4075, USA
    Nature 442:195-8. 2006
    ..These performance results and their implications for system design should substantially increase the clinical viability of BCIs in humans...
  3. ncbi High surface energy enhances cell response to titanium substrate microstructure
    G Zhao
    Georgia Institute of Technology, Atlanta, GA 30332, USA
    J Biomed Mater Res A 74:49-58. 2005
    ..This suggests that increased bone formation observed on modified Ti surfaces in vivo is due in part to stimulatory effects of high surface energy on osteoblasts...
  4. ncbi A prospective, randomized, multicenter Food and Drug Administration investigational device exemptions study of lumbar total disc replacement with the CHARITE artificial disc versus lumbar fusion: part I: evaluation of clinical outcomes
    Scott Blumenthal
    Texas Back Institute, Plano, Texas 75093, USA
    Spine (Phila Pa 1976) 30:1565-75; discussion E387-91. 2005
    ..A prospective, randomized, multicenter, Food and Drug Administration-regulated Investigational Device Exemption clinical trial...
  5. ncbi Results from the multicenter Boston Type 1 Keratoprosthesis Study
    Brian L Zerbe
    Albany Medical College, Albany, New York, USA
    Ophthalmology 113:1779.e1-7. 2006
    ..To report indications, practices, complications, and outcomes from the first multicenter study on the Boston Type 1 keratoprosthesis...
  6. ncbi Fabrication methods of porous metals for use in orthopaedic applications
    Garrett Ryan
    National University of Ireland, Department of Mechanical and Biomedical Engineering, Nun s Island, Galway, Ireland
    Biomaterials 27:2651-70. 2006
    ..This review summarises all known methods for fabricating such porous metallic scaffolds...
  7. pmc Interspinous implants (X Stop, Wallis, Diam) for the treatment of LSS: is there a correlation between radiological parameters and clinical outcome?
    Rolf Sobottke
    Department of Orthopaedic and Trauma Surgery, University of Cologne, Joseph Stelzmann Str 9, 50924, Cologne, Germany
    Eur Spine J 18:1494-503. 2009
    ..The interspinous implant offers significant, longlasting symptom control, even if initially significant radiological changes seem to revert toward the initial values ("loss of correction")...
  8. doi Evaluation of the stability of Boston type I keratoprosthesis-donor cornea interface using anterior segment optical coherence tomography
    Julian P S Garcia
    The New York Eye and Ear Infirmary, New York, USA
    Cornea 29:1031-5. 2010
    ..The presence of a gap would raise concerns of a possible pathway for the exchange of extraocular fluid with the anterior chamber...
  9. ncbi Microbial keratitis after intrastromal corneal ring segment implantation
    M Emilia Mulet
    Department of Ophthalmology, Miguel Hernandez University, Alicante, Spain
    J Refract Surg 26:364-9. 2010
    ..To evaluate the incidence of acute microbial keratitis after intrastromal corneal ring segment implantation and to investigate whether microbial keratitis is related to the intrastromal corneal ring type or surgical technique...
  10. doi Long-term results following titanium cranioplasty of large skull defects
    Mario Cabraja
    Department of Neurosurgery, Charite Universitatsmedizin Berlin, Germany
    Neurosurg Focus 26:E10. 2009
    ..In this retrospective study of large skull defects, the authors compared computer-assisted design/computer-assisted modeled (CAD/CAM) titanium implants for cranioplasty with other frequently used materials described in literature...
  11. ncbi Customised fabricated implants after previous failed cranioplasty
    Raymond C W Goh
    Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu Shin Street, Kwei Shan, Taoyuan 333, Taiwan
    J Plast Reconstr Aesthet Surg 63:1479-84. 2010
    ..Customised fabricated alloplastic implants provide a safe, accurate and efficient way of restoring normal cranial contours in patients with cranial defects who have had previous failed cranioplasties...
  12. ncbi Advances in Boston keratoprosthesis: enhancing retention and prevention of infection and inflammation
    Bilal F Khan
    Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Boston, MA 02114, USA
    Int Ophthalmol Clin 47:61-71. 2007
  13. ncbi Taylored implants for alloplastic cranioplasty--clinical and surgical considerations
    B Hoffmann
    Neurosurgical Clinic, Clemenshospital Münster, Germany
    Acta Neurochir Suppl 93:127-9. 2005
    ..Application of this technique is limited by cost, nonetheless it is recommended for extensive reconstruction of the skull...
  14. ncbi Computer aided design of large-format prefabricated cranial plates
    David Dean
    Department of Neurological Surgery and the Research Institute, University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
    J Craniofac Surg 14:819-32. 2003
    ..Therefore, the authors conclude that their new production method provides a better result with less expense than current methods for preoperative or intraoperative fabrication of large-format cranioplasties...
  15. ncbi Late bacterial keratitis after implantation of intrastromal corneal ring segments
    Tristan Bourcier
    Quinze Vingts National Center of Ophthalmology, Paris, France
    J Cataract Refract Surg 29:407-9. 2003
    ..The infiltrates progressed despite treatment with topical fortified and systemic antibiotics. The Intacs were removed. The keratitis slowly resolved, and the patient recovered a best corrected visual acuity of 20/20...
  16. ncbi The Otto Aufranc Award: bone augmentation around and within porous implants by local bisphosphonate elution
    Michael Tanzer
    Department of Surgery, McGill University, Montreal, Quebec, Canada
    Clin Orthop Relat Res 441:30-9. 2005
    ..The concept represents a potential tool for restoration of bone stock and enhancement of implant fixation in primary and revision cementless joint arthroplasty surgeries in the face of compromised or deficient bone...
  17. ncbi Low stiffness porous Ti structures for load-bearing implants
    B Vamsi Krishna
    W M Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164 2920, USA
    Acta Biomater 3:997-1006. 2007
    ..to reduce effective stiffness for load-bearing implants. Young's modulus and 0.2% proof strength of these porous Ti samples having 35-42vol.% porosity are found to be similar to those of human cortical bone...
  18. doi Boston keratoprosthesis outcomes and complications
    Hall F Chew
    Cornea Service, Wills Eye Institute, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
    Cornea 28:989-96. 2009
    ..To evaluate the outcomes of the Boston Keratoprosthesis (KPro) at our institution...
  19. ncbi Overcoming artifacts from metallic orthopedic implants at high-field-strength MR imaging and multi-detector CT
    Mi Jung Lee
    Department of Diagnostic Radiology and Research Institute of Radiological Science and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 134 Sincheon Dong Seodaemun Gu, Seoul 120 752, Republic of Korea
    Radiographics 27:791-803. 2007
    ..A comparison of images obtained with different hardware and different acquisition and reconstruction parameters facilitates an understanding of methods for reducing or overcoming artifacts related to metallic implants...
  20. ncbi Vestibular prostheses: the engineering and biomedical issues
    C Wall
    Harvard Medical School, Department of Otology and Laryngology, Boston, MA 02114, USA
    J Vestib Res 12:95-113. 2002
    ..In this "white paper", we consider these issues in the context of prototype baseline prosthetic devices...
  21. pmc Microbiologic diagnosis of prosthetic shoulder infection by use of implant sonication
    Kerryl E Piper
    Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, 200 First St S W, Rochester, MN 55905, USA
    J Clin Microbiol 47:1878-84. 2009
    ..9%) and sonicate fluid culture (40.9%). All subjects from whom P. acnes was isolated from sonicate fluid were male. We conclude that sonicate fluid culture is useful for the diagnosis of prosthetic shoulder infection...
  22. ncbi Local alendronate increases fixation of implants inserted with bone compaction: 12-week canine study
    Thomas Jakobsen
    Orthopaedic Research Laboratory, Department of Orthopaedics, Aarhus University Hospital, Norrebrogade 44, Bldg 1A, DK 8000 Aarhus C, Denmark
    J Orthop Res 25:432-41. 2007
    ..3-fold). This study indicates that local alendronate treatment can increase early implant osseointegration and biomechanical fixation of implants inserted by use of bone compaction. Long term effects remain unknown...
  23. ncbi Direct cortical control of 3D neuroprosthetic devices
    Dawn M Taylor
    Department of Bioengineering, Arizona State University, Tempe, AZ 85287 6006, USA
    Science 296:1829-32. 2002
    ..By using control algorithms that track these changes, subjects made long sequences of 3D movements using far fewer cortical units than expected. Daily practice improved movement accuracy and the directional tuning of these units...
  24. doi In vivo gene expression in response to anodically oxidized versus machined titanium implants
    Omar Omar
    Department of Biomaterials, Sahlgrenska Academy at University of Gothenburg, Sweden
    J Biomed Mater Res A 92:1552-66. 2010
    ....
  25. doi Clinical features and prognosis of Boston type I keratoprosthesis-associated corneal melt
    Canan Asli Utine
    Ocular Surface Disease and Dry Eye Clinic, Cornea and External Disease Service, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 9238, USA
    Ocul Immunol Inflamm 19:413-8. 2011
    ..To describe the clinical features and outcomes of corneal melt associated with Boston type I keratoprosthesis (KPro) implantation...
  26. doi Expanding indications for the Boston keratoprosthesis
    Kathryn A Colby
    Cornea and Refractive Surgery, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Curr Opin Ophthalmol 22:267-73. 2011
    ..To review emerging indications for the Boston keratoprosthesis (KPro) and to discuss current research underway to improve clinical outcomes...
  27. pmc Effect of the cord pretension of the Dynesys dynamic stabilisation system on the biomechanics of the lumbar spine: a finite element analysis
    Chien Lin Liu
    Department of Orthopaedic Surgery, Taipei Veterans General Hospital, Taipei, Taiwan
    Eur Spine J 20:1850-8. 2011
    ..In addition, use of a 300 N cord pretension causes a much higher stiffness at the implanted level when compared with the intact lumbar spine...
  28. ncbi Visual perception in a blind subject with a chronic microelectronic retinal prosthesis
    Mark S Humayun
    Doheny Retina Institute at the Doheny Eye Institute, University of Southern California, 1450 San Pablo Street Room 3600, Keck School of Medicine, Los Angeles, CA 14627, USA
    Vision Res 43:2573-81. 2003
    ..In addition, the subject was able to use a camera to detect the presence or absence of ambient light, to detect motion, and to recognize simple shapes...
  29. doi Occult spinous process fractures associated with interspinous process spacers
    David H Kim
    Tufts University School of Medicine, 125 Parker Hill Ave, Boston, MA 02120, USA
    Spine (Phila Pa 1976) 36:E1080-5. 2011
    ..Prospective observational study...
  30. doi Lumbar interspinous spacers: a systematic review of clinical and biomechanical evidence
    Syed M R Kabir
    National Hospital for Neurology and Neurosurgery, London, United Kingdom
    Spine (Phila Pa 1976) 35:E1499-506. 2010
    ..Systematic review...
  31. ncbi Enhanced functions of osteoblasts on nanometer diameter carbon fibers
    Kathy L Elias
    Department of Biomedical Engineering, Purdue University, West Lafayette, IN 47907 1296, USA
    Biomaterials 23:3279-87. 2002
    ....
  32. ncbi Short-term visual outcomes of Boston type 1 keratoprosthesis implantation
    Karen Dunlap
    Ocular Surface Diseases and Dry Eye Clinic, The Wilmer Eye Institute, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287 9238, USA
    Ophthalmology 117:687-92. 2010
    ..To report the short-term visual outcomes after keratoprosthesis implantation...
  33. doi Expanding application of the Boston type I keratoprosthesis due to advances in design and improved post-operative therapeutic strategies
    Aisha S Traish
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
    Semin Ophthalmol 25:239-43. 2010
    ..To evaluate how the advances in design of the Boston type I keratoprosthesis and in the treatment strategies to conquer the post operative complications have expanded the indications and application of this technology...
  34. ncbi An overview of nano-polymers for orthopedic applications
    Ganesan Balasundaram
    Divisions of Engineering and Orthopaedics, Brown University, Box D, 224 Barus and Holley, 182 Hope Street, Providence, RI 02912, USA
    Macromol Biosci 7:635-42. 2007
    ..Nanotechnology (or the use of nanomaterials) is providing a wide range of new materials to improve the current short lifetimes of orthopedic implants...
  35. doi The Boston keratoprosthesis in Stevens-Johnson syndrome
    Rony R Sayegh
    Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 145:438-44. 2008
    ..To evaluate the use of the Boston keratoprosthesis (KPro) in patients with Stevens-Johnson syndrome (SJS)...
  36. doi Boston type 1 keratoprosthesis for severe blinding vernal keratoconjunctivitis and Mooren's ulcer
    Sayan Basu
    Cornea and Anterior Segment Service, LV Prasad Eye Institute, Kallam Anji Reddy Campus, Banjara Hills Road No 2, Hyderabad, India
    Int Ophthalmol 31:219-22. 2011
    ..To our knowledge this is the first report of successful Boston keratoprosthesis implantation for these two unusual indications...
  37. doi The role of soft contact lenses as an adjunct to the Boston keratoprosthesis
    Mona Harissi-Dagher
    Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    Int Ophthalmol Clin 48:43-51. 2008
  38. doi The clinical impact of incomplete left atrial appendage closure with the Watchman Device in patients with atrial fibrillation: a PROTECT AF (Percutaneous Closure of the Left Atrial Appendage Versus Warfarin Therapy for Prevention of Stroke in Patients Wit
    Juan F Viles-Gonzalez
    Mount Sinai School of Medicine, New York City, New York, USA
    J Am Coll Cardiol 59:923-9. 2012
    ..Plymouth, Minnesota)...
  39. doi Mechanical evaluation of porous titanium (Ti6Al4V) structures with electron beam melting (EBM)
    Jayanthi Parthasarathy
    School of Industrial Engineering, University of Oklahoma, Norman, OK 73019, USA
    J Mech Behav Biomed Mater 3:249-59. 2010
    ....
  40. pmc Two-year results of interspinous spacer (X-Stop) implantation in 175 patients with neurologic intermittent claudication due to lumbar spinal stenosis
    Johannes Kuchta
    Department of Neurosurgery, MediaParc Clinic, Cologne, Germany
    Eur Spine J 18:823-9. 2009
    ..Functional (upright-) MRI examinations were able to demonstrate the positional-dependent stenosis. If available, fMRI represents the most helpful radiologic examination in assessing the outcome of interspinous spacer implantation...
  41. doi Aperius PercLID stand alone interspinous system for the treatment of degenerative lumbar stenosis: experience on 152 cases
    Piervittorio Nardi
    Neurosurgical Unit, Policlinico Casilino, Rome, Italy
    J Spinal Disord Tech 23:203-7. 2010
    ..This study is a retrospective clinical investigation of a new interspinous device implanted via a totally percutaneous technique involving 152 consecutive patients...
  42. ncbi Quality of life of lumbar stenosis-treated patients in whom the X STOP interspinous device was implanted
    Ken Y Hsu
    Department of Orthopaedics, St Mary s Medical Center, St Mary s Spine Center, San Francisco, California 94117, USA
    J Neurosurg Spine 5:500-7. 2006
    ....
  43. ncbi Cyclic loads do not compromise functionality of the interspinous spacer or cause damage to the spinal segment: an in vitro analysis
    Amanesh Goyal
    Engineering Center for Orthopaedic Research Excellence E CORE, Departments of Bioengineering and Orthopaedic Surgery, Colleges of Engineering and Medicine, University of Toledo, Toledo, Ohio 43606, USA
    J Long Term Eff Med Implants 18:289-302. 2008
    ..A biomechanical study to evaluate the effects of interspinous spacer under cyclic complex loading...
  44. ncbi One-year results of X Stop interspinous implant for the treatment of lumbar spinal stenosis
    Manal Siddiqui
    Department of Orthopaedics, Woodend Hospital, Aberdeen, Scotland, UK
    Spine (Phila Pa 1976) 32:1345-8. 2007
    ..Prospective observational study...
  45. ncbi Pore throat size and connectivity determine bone and tissue ingrowth into porous implants: three-dimensional micro-CT based structural analyses of porous bioactive titanium implants
    Bungo Otsuki
    Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Shogoin, Kyoto 606 8507, Japan
    Biomaterials 27:5892-900. 2006
    ..Data obtained suggest that this sort of novel analysis is useful for evaluating bone and tissue ingrowth into porous biomaterials...
  46. ncbi The auditory midbrain implant: a new auditory prosthesis for neural deafness-concept and device description
    Thomas Lenarz
    Otorhinolaryngology Department, Medical University of Hannover, Germany
    Otol Neurotol 27:838-43. 2006
    ..Practical considerations for implementation of the AMI will also be discussed...
  47. ncbi INTACS inserts for treating keratoconus: one-year results
    J Colin
    Bordeaux University Hospital, Hopital Pellegrin, Bordeaux, France
    Ophthalmology 108:1409-14. 2001
    ..The corneal steepening and astigmatism associated with keratoconus were reduced, and visual acuity was improved with treatment in almost all eyes...
  48. ncbi Metal artifact reduction in CT using tissue-class modeling and adaptive prefiltering
    Matthieu Bal
    Philips Research, Aachen, Germany
    Med Phys 33:2852-9. 2006
    ..Furthermore, the novel approach improves detectability of organ contours. This can be of great relevance, for instance, in radiation therapy planning, where images affected by metal artifacts may lead to suboptimal treatment plans...
  49. ncbi Design and manufacturing of cranioplasty implants by 3-axis cnc milling
    L C Hieu
    School of Advanced Technologies, Asian Institute of Technology, Thailand
    Technol Health Care 10:413-23. 2002
    ..The cost of implants is acceptable for the ASEAN region...
  50. ncbi Towards on-line adaptation of neuro-prostheses with neuronal evaluation signals
    David Rotermund
    Institute for Theoretical Physics, University Bremen, Otto Hahn Allee 1, 28334 Bremen, Germany
    Biol Cybern 95:243-57. 2006
    ..Furthermore, the adaptation is shown to be stable against large changes in neural encoding and/or in the recording itself...
  51. ncbi Review of the available urethral bulking agents
    Deborah J Lightner
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Curr Opin Urol 12:333-8. 2002
    ..We review the new studies on the development and on the current trials of bulking agents...
  52. ncbi Repair of the pectus deformity: results of the Ravitch approach in the current era
    J Terrance Davis
    Department of Cardiothoracic Surgery, Columbus Children s Hospital, ED 620 Education Building, 700 Children s Drive, Columbus, OH 43221, USA
    Ann Thorac Surg 78:421-6. 2004
    ..Efforts to evaluate this new approach have been hampered by lack of comparative information regarding outcomes of the standard Ravitch approach. We use a modified Ravitch procedure, and present our series as a basis for comparison...
  53. ncbi Cranioplasty with individual carbon fibre reinforced polymere (CFRP) medical grade implants based on CAD/CAM technique
    W Saringer
    Department of Neurosurgery, University of Vienna, Medical School, Vienna, Austria
    Acta Neurochir (Wien) 144:1193-203. 2002
    ..The authors present a new method for the reconstruction of large or complex-formed cranial bone defects using prefabricated, computer-generated, individual CFRP (carbon fibre reinforced plastics) medical grade implants...
  54. ncbi Bone ingrowth in porous titanium implants produced by 3D fiber deposition
    Jia Ping Li
    Department of Tissue Regeneration, Institute for Biomedical Technology, University of Twente, The Netherlands
    Biomaterials 28:2810-20. 2007
    ..In vivo results showed that increase of porosity and pore size, and thus increase of permeability of titanium alloy implants positively influenced their osteoconductive properties...
  55. ncbi Capsular tension ring use in a patient with congenital coloboma of the lens
    Hidenobu Mizuno
    Department of Ophthalmology, Kyoto Second Red Cross Hospital, Kyoto, Japan
    J Cataract Refract Surg 30:503-6. 2004
    ..The visual acuity recovered to 20/20 in both eyes. Capsular tension ring implantation can facilitate cataract surgery in coloboma of the lens, even in long-term and continuous lens capsule deformity...
  56. ncbi Lichtenstein tension-free hernioplasty: its inception, evolution, and principles
    Parviz K Amid
    Lichtenstein Hernia Institute, 5901 W Olympic Boulevard Suite 207, Los Angeles, CA 90036, USA
    Hernia 8:1-7. 2004
    ....
  57. doi The Boston type I keratoprosthesis: improving outcomes and expanding indications
    Anthony J Aldave
    Cornea Service, The Jules Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Ophthalmology 116:640-51. 2009
    ..To report the usefulness of the Boston type I keratoprosthesis (Massachusetts Eye and Ear Infirmary, Boston, MA) in the management of corneal opacification, corneal limbal stem cell failure, or both in a large single-surgeon series...
  58. ncbi In vivo biocompatibility testing of peek polymer for a spinal implant system: a study in rabbits
    Charles H Rivard
    Pediatric Research Center, Sainte Justine Hospital, Montreal, Quebec, Canada
    J Biomed Mater Res 62:488-98. 2002
    ..Neither necrosis nor swelling of the dura mater and nerve roots was observed. The PEEK polymer is harmless to the spinal cord; thus it might be used as component in the spinal implant system...
  59. ncbi CAD generated mold for preoperative implant fabrication in cranioplasty
    J Wulf
    Department of Anatomy, University of Luebeck, 23538 Luebeck, Germany
    Stud Health Technol Inform 111:608-10. 2005
    ..Implants were fabricated using a Rapid prototyping (RP) models of the skull built by Fused Deposition Modeling (FDM). In addition a mold of the defect was generated by CAD techniques, that can serve as a template for implant design...
  60. ncbi Keratitis after implantation of intrastromal corneal ring segments
    Raneen Shehadeh-Masha'our
    Department of Ophthalmology, Bnai Zion Medical Center Rappaport Faculty of Medicine Technion, Golomb Street 47, Haifa, Israel
    J Cataract Refract Surg 30:1802-4. 2004
    ..The patient was treated with topical and subconjunctival antibiotics and channel irrigation. The keratitis resolved, leaving a neovascularized opacity at the nasal part of the lower channel...
  61. ncbi Experimental and clinical performance of porous tantalum in orthopedic surgery
    Brett Russell Levine
    Orthopaedics, Rush University Medical Center, 1725 E Harrison Street, Suite 1063, Chicago, IL 60612, USA
    Biomaterials 27:4671-81. 2006
    ..The development of porous tantalum is in its early stages of evolution and the following represents a review of its biomaterial properties and applications in orthopedic surgery...
  62. ncbi Tracheal replacement: a critical review
    Hermes C Grillo
    Division of General Thoracic Surgery, Massachusetts General Hospital, Boston 02114, USA
    Ann Thorac Surg 73:1995-2004. 2002
    ..Approaches have included use of foreign materials, nonviable tissue, autogenous tissue, tissue engineering, and transplantation. Biological problems in each category are noted...
  63. ncbi Endoprosthetic replacement of the humerus combined with trapezius and latissimus dorsi transfer: a report of three patients
    G Gosheger
    Department of Orthopaedics, Westfaelische Wilhelms Universitaet Muenster, Albert Schweitzer Strasse 33, 48149, Munster, Germany
    Arch Orthop Trauma Surg 125:62-5. 2005
    ..To improve the functional outcome after proximal and/or total humerus replacement, we combined the surgical procedures described by Bateman and Gerber...
  64. doi Bio-inspired sensorization of a biomechatronic robot hand for the grasp-and-lift task
    B B Edin
    Physiology Section, Department of Integrative Medical Biology, Umea University, SE 901 87 Umea, Sweden
    Brain Res Bull 75:785-95. 2008
    ..We discuss the importance of the sensorized hand as a test bed for low-level grasp controllers and for the development of functional sensory feedback from prosthetic devices...
  65. ncbi Efficiency of systematic sampling in histomorphometric bone research illustrated by hydroxyapatite-coated implants: optimizing the stereological vertical-section design
    S Overgaard
    Department of Orthopaedics, Aarhus University Hospital, Denmark
    J Orthop Res 18:313-21. 2000
    ....
  66. pmc Planning target volume margins for prostate radiotherapy using daily electronic portal imaging and implanted fiducial markers
    David Skarsgard
    Department of Radiation Oncology, Tom Baker Cancer Center and University of Calgary, 1331 29 Street NW, Calgary, Alberta, Canada
    Radiat Oncol 5:52. 2010
    ..The purpose of this study was to estimate CTV to PTV margin requirements, without and with the use of this image guidance strategy...
  67. ncbi Antimicrobial peptides on calcium phosphate-coated titanium for the prevention of implant-associated infections
    Mehdi Kazemzadeh-Narbat
    Department of Materials Engineering, University of British Columbia, 309 6350 Stores Road, Vancouver, BC, V6T 1Z4, Canada
    Biomaterials 31:9519-26. 2010
    ..A device coated with CaP-Tet213 could be a potential solution for the prevention of the peri-implant infection in orthopaedics...
  68. ncbi The effect of an interspinous process implant on facet loading during extension
    Craig M Wiseman
    San Francisco Orthopaedic Residency Program, San Francisco, California, USA
    Spine (Phila Pa 1976) 30:903-7. 2005
    ..Facet loading parameters of lumbar cadaver spines were measured during extension before and after placement of an interspinous process implant...
  69. doi The potential role of human osteoblasts for periprosthetic osteolysis following exposure to wear particles
    Katrin Lochner
    Department of Orthopaedics, University of Rostock, D 18057 Rostock, Germany
    Int J Mol Med 28:1055-63. 2011
    ..Among the reference particles, which caused less altered reactions in the metabolism of osteoblasts in general, ZrO2 can be assumed as the material with the smallest cell biological effects...
  70. ncbi Clinical results of total lumbar disc replacement with ProDisc II: three-year results for different indications
    Christoph J Siepe
    Spine Center, OrthoCenter Munich, Munich, Germany
    Spine (Phila Pa 1976) 31:1923-32. 2006
    ..Prospective study analyzing midterm clinical results of total lumbar disc replacement (ProDisc II) for different indications...
  71. ncbi AlphaCor keratoprosthesis: postoperative development of six patients
    S A Holak
    Eye Department of Schlosspark Klinik, Berlin, Germany
    Graefes Arch Clin Exp Ophthalmol 247:535-9. 2009
    ..To evaluate the efficacy and visual restoring of six patients with complete corneal opacification and deep neovascularizations treated with AlphaCor...
  72. doi Early and temporary use of finger prosthetics to aid rehabilitation
    Barbra Samph Almond
    Inova Physical Therapy Centers, Centreville, Virginia 20121, USA
    J Hand Ther 24:62-5. 2011
    ..The splint is designed to assist with the compensatory pain that people frequently feel as they learn to reuse their hand and to give people an understanding of what it feels like to have a prosthetic digit...
  73. ncbi Audiologic outcomes with the penetrating electrode auditory brainstem implant
    Steven R Otto
    House Ear Institute, Los Angeles, California 90057, USA
    Otol Neurotol 29:1147-54. 2008
    ..Approximately 8 weeks after implantation, PABI devices were activated and tested at our tertiary clinical and research facility. Mean follow-up time was 33.8 months...
  74. pmc Proximal humerus reconstructions for tumors
    Benjamin K Potter
    Musculoskeletal Oncology, University of Miami Miller School of Medicine, Miami, FL, USA
    Clin Orthop Relat Res 467:1035-41. 2009
    ..Because of the unacceptable complication rate, we do not recommend osteoarticular allograft reconstruction for routine use in the proximal humerus...
  75. pmc Strategies and applications for incorporating physical and chemical signal gradients in tissue engineering
    Milind Singh
    Department of Chemical and Petroleum Engineering, University of Kansas, Lawrence, Kansas 66045 7609, USA
    Tissue Eng Part B Rev 14:341-66. 2008
    ..In the future, in vivo applications will shed more light on the performance of gradient-based mechanical integrity and signal delivery strategies compared to traditional tissue engineering approaches...
  76. ncbi Tissue engineered epithelial cell sheets for the creation of a bioartificial trachea
    Masato Kanzaki
    The Department of Surgery I, Tokyo Women s Medical University, Tokyo, Japan
    Tissue Eng 12:1275-83. 2006
    ..These results therefore demonstrate that these tracheal epithelial cell sheets can create an epithelial lining on the luminal surface of a bioartificial trachea...
  77. doi Ultrasonographic monitoring of implant thickness after augmentation rhinoplasty with expanded polytetrafluoroethylene
    Yong Gi Jung
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Am J Rhinol Allergy 23:105-10. 2009
    ..However, changes in the thickness of ePTFE after its use in augmentation rhinoplasty with a noninvasive object method are not well understood...
  78. ncbi Interface interactions of osteoblasts with structured titanium and the correlation between physicochemical characteristics and cell biological parameters
    J G Barbara Nebe
    Department of Internal Medicine, University of Rostock, BMFZ, Schillingallee 69, D 18057 Rostock, Germany
    Macromol Biosci 7:567-78. 2007
    ..We revealed a correlation for integrin expression and formation, adhesion, spreading, proliferation, and bone sialo protein expression with the physicochemical parameters of the titanium surfaces...
  79. ncbi Amniotic membrane immobilized poly(vinyl alcohol) hybrid polymer as an artificial cornea scaffold that supports a stratified and differentiated corneal epithelium
    Yuichi Uchino
    Department of Ophthalmology, Tokyo Dental College, Chiba, Japan
    J Biomed Mater Res B Appl Biomater 81:201-6. 2007
    ..Corneal epithelialization on PVA-AM in rabbit corneas improved over PVA-COL, suggesting the possibility of using PVA-AM as a biocompatible hybrid material for keratoprosthesis...
  80. doi Silicon induces minimal thromboinflammatory response during 28-day intravascular implant testing
    Melissa E Melvin
    Section of Plastic Surgery, University of Michigan, 1500 E Medical Center Dr, 2130 Taubman Center, Ann Arbor, Michigan, USA
    ASAIO J 56:344-8. 2010
    ..PEG-treated silicon seems to be biocompatible and holds potential as an excellent material with which to construct an implantable, miniaturized hemofiltration membrane...
  81. ncbi Fabrication, implantation, elution, and retrieval of a steroid-loaded polycaprolactone subretinal implant
    Nathan R F Beeley
    Doheny Retina Institute, Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine, University of Southern California, 1450 San Pablo Street, Los Angeles, CA 90033, USA
    J Biomed Mater Res A 73:437-44. 2005
    ..Histology and device retrieval after implantation revealed minimal encapsulation and good preservation of cellular morphology during the follow-up period and a more fibrous polymer microstructure of the implant...
  82. pmc Interspinous spacers in the treatment of degenerative lumbar spinal disease: our experience with DIAM and Aperius devices
    Antonio P Fabrizi
    Department of Neurosurgery, Maria Pia Hospital, Turin, Italy
    Eur Spine J 20:S20-6. 2011
    ..Both techniques are safe, simple and less technically demanding. These approaches appear to be an effective alternative in selected cases, although conventional posterior lumbar decompression and fusion still may be required...
  83. ncbi Substratum roughness alters the growth, area, and focal adhesions of epithelial cells, and their proximity to titanium surfaces
    B Baharloo
    University of British Columbia, Faculty of Dentistry, Vancouver, Canada
    J Biomed Mater Res A 74:12-22. 2005
    ..Therefore, the size and shape of surface features are important determinants of epithelial adhesive behavior and epithelial coverage of rough surfaces would be difficult to attain if such surfaces become exposed...
  84. ncbi Controlling cellular reactive responses around neural prosthetic devices using peripheral and local intervention strategies
    William Shain
    Wadsworth Center, Albany, NY 12201 0509, USA
    IEEE Trans Neural Syst Rehabil Eng 11:186-8. 2003
    ..Incorporating these strategies on micromachined devices may provide an intervention strategy that will insure the chronic functioning of electrodes on intracortical neuroprosthetic devices...
  85. ncbi The Chirila Keratoprosthesis: phase I human clinical trial
    Geoffrey J Crawford
    Lions Eye Institute and Centre for Ophthalmology and Visual Science, University of Western Australia, Perth, Australia
    Ophthalmology 109:883-9. 2002
    ..To undertake a preliminary safety and performance evaluation of an artificial cornea, the Chirila Keratoprosthesis, in human patients...
  86. ncbi Evaluation of digital prostheses
    A Alison
    Sunnybrook Health Science Centre, Toronto, Ontario, Canada
    J Hand Surg Am 17:923-6. 1992
    ..The majority of patients requested prostheses for esthetic reasons. While they reported satisfaction with the appearance of the prostheses, at 3 years 36% of the patients no longer continue to use the prostheses...
  87. ncbi Nanostructured surfaces for bone biotemplating applications
    Ketul C Popat
    Department of Physiology, University of California at San Francisco, Room QB3 203C, Box 2520, Mission Bay Campus, 1700 4th Street, San Francisco, California 94143 2520, USA
    J Orthop Res 24:619-27. 2006
    ..Over the 4-week study, the nanostructured surfaces demonstrated improved osteoblast adhesion and proliferation and increased alkaline phosphatase activity and matrix production compared to non-nanostructured control surfaces...
  88. ncbi Benefits and use of digital prostheses
    B P Pereira
    Department of Orthopaedic Surgery, National University Hospital, Singapore, Republic of Singapore
    J Hand Surg Am 21:222-8. 1996
    ....
  89. ncbi Periprosthetic fractures of the humerus
    Edward B McDonough
    Department of Orthopaedics, Wright State University, Miami Valley Hospital, 128 E Apple St, Room 2830, Dayton, OH 45409, USA
    Am J Orthop (Belle Mead NJ) 34:586-91. 2005
    ..There has been some support for conservative treatment of long oblique or spiral postoperative fractures. Postoperative diaphyseal fractures distal to the stem generally are well maintained with standard fracture management...
  90. ncbi Development and clinical assessment of an artificial cornea
    C Hicks
    Lions Eye Institute, Nedlands, Western Australia
    Prog Retin Eye Res 19:149-70. 2000
    ..Pilot data from a clinical trial is presented and the priorities for future research are discussed...
  91. ncbi Vancomycin bound to Ti rods reduces periprosthetic infection: preliminary study
    Valentin Antoci
    Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA, USA
    Clin Orthop Relat Res 461:88-95. 2007
    ..Vancomycin-modified implants showed superior inhibition of bacterial attachment and proliferation compared to control titanium surfaces...
  92. pmc Compressive osseointegration promotes viable bone at the endoprosthetic interface: retrieval study of Compress implants
    M J Kramer
    Orthopaedic Oncology Service, UCSF Comprehensive Cancer Center, San Francisco, CA 94115 1939, USA
    Int Orthop 32:567-71. 2008
    ..No patient demonstrated histological evidence of osteonecrosis. In fact, new woven bone and other findings consistent with viable bone were noted in all of the retrieved specimens...
  93. ncbi Neuroprosthetics: in search of the sixth sense
    Alison Abbott
    Nature 442:125-7. 2006
  94. ncbi Intracorneal rings for keratoconus and keratectasia
    Aylin Ertan
    Kudret Eye Hospital, Ankara, Turkey, and the Bordeaux University, Bordeaux, France
    J Cataract Refract Surg 33:1303-14. 2007
    ..This article reviews the latest data published or presented at meetings on the correction of keratoconus and keratectasia by intracorneal ring segments...
  95. doi Prospective, randomized trial of metal-on-metal artificial lumbar disc replacement: initial results for treatment of discogenic pain
    Rick C Sasso
    Clinical Orthopaedic Surgery, Indiana Spine Group, Indiana University School of Medicine, Indianapolis, IN 46260, USA
    Spine (Phila Pa 1976) 33:123-31. 2008
    ....
  96. ncbi Vancomycin covalently bonded to titanium alloy prevents bacterial colonization
    Valentin Antoci
    Department of Orthopaedic Surgery, Thomas Jefferson University, 1015 Walnut Street, Suite 501, Philadelphia, Pennsylvania 19107, USA
    J Orthop Res 25:858-66. 2007
    ..These results demonstrate that we have effectively engineered a stable, bactericidal Ti surface. This new surface holds great promise in terms of mitigating or preventing periprosthetic infection...
  97. ncbi Posterior lumbar interbody fusion (PLIF) with cages and local bone graft in the treatment of spinal stenosis
    Hans Trouillier
    Orthopaedic, Trauma and Spine Department, Franziskus Hospital Bielefeld, Germany
    Acta Orthop Belg 72:460-6. 2006
    ..The results observed in our group of patients suggest that local autologous bone graft procured from the posterior elements after decompression is an adequate material for bone grafting in this procedure...
  98. ncbi Aseptic loosening is uncommon with uncemented proximal tibia tumor prostheses
    Michael N Flint
    University Musculoskeletal Oncology Unit, Mount Sinai Hospital, 476E 600 University Avenue, Toronto, Ontario M5G 1X5, Canada
    Clin Orthop Relat Res 450:52-9. 2006
    ..Three patients with knee extensor complications had inferior functional outcomes. Aseptic loosening is uncommon with uncemented proximal tibia reconstruction, but decreasing other complications at this location remains challenging...
  99. ncbi Development of continuous implantable renal replacement: past and future
    William H Fissell
    Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Transl Res 150:327-36. 2007
    ..These advances in membrane technology are fundamentally enabling for a paradigm shift from an in-center to implantable dialysis system...
  100. ncbi European clinical evaluation: use of Intacs for the treatment of keratoconus
    Joseph Colin
    Service d Ophtalmologie, Bordeaux, France
    J Cataract Refract Surg 32:747-55. 2006
    ..To evaluate the safety and efficacy of Intacs inserts in keratoconic eyes to alter corneal shape and refractive power and stabilize the progression of corneal ectasia...
  101. ncbi Nanobiomaterial applications in orthopedics
    Elizabeth M Christenson
    Department of Bioengineering MS142, Rice University, PO Box 1892, Houston, Texas 77251 1892, USA
    J Orthop Res 25:11-22. 2007
    ..Overall, current trends in nanobiotechnology foreshadow a bright future through the use of nanobiomaterials in the orthopedic domain...

Research Grants229 found, 100 shown here

  1. High-Resolution Whole-Breast MRI at 3.0T
    BRIAN ANDREW HARGREAVES; Fiscal Year: 2010
    ..This research will develop much higher resolution MRI, allowing it to better classify small lesions, prevent unnecessary biopsy, and detect cancer earlier. ..
  2. INDUCTION OF DE NOVO DENTAL PAPILLAE FROM YOUNG RODENT
    Mina Mina; Fiscal Year: 2001
    ..As a result tooth loss is currently being treated by a variety of traditional clinical therapies using prostheses and implants. However, these devices are incapable of replacing all the junctions of the original tooth, often fail ..
  3. INDUCTION OF DE NOVO DENTAL PAPILLAE FROM YOUNG RODENT
    Mina Mina; Fiscal Year: 2000
    ..As a result tooth loss is currently being treated by a variety of traditional clinical therapies using prostheses and implants. However, these devices are incapable of replacing all the junctions of the original tooth, often fail ..
  4. Processing of Materials for Improved Biocompatibility
    Michael Matthews; Fiscal Year: 2003
    ..will conduct basic research to improve biocompatibility of materials used in biomedical devices such as prostheses and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing ..
  5. Processing of Materials for Improved Biocompatibility
    Michael Matthews; Fiscal Year: 2004
    ..will conduct basic research to improve biocompatibility of materials used in biomedical devices such as prostheses and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing ..
  6. Processing of Materials for Improved Biocompatibility
    Michael Matthews; Fiscal Year: 2004
    ..will conduct basic research to improve biocompatibility of materials used in biomedical devices such as prostheses and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing ..
  7. Processing of Materials for Improved Biocompatibility
    Michael Matthews; Fiscal Year: 2002
    ..will conduct basic research to improve biocompatibility of materials used in biomedical devices such as prostheses and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing ..
  8. Data Communication with Implantable Micro Devices
    Mingui Sun; Fiscal Year: 2002
    ..We will implant this device within the brain of laboratory dogs and evaluate its performance. ..
  9. A Unified Sensor System for Ubiquitous Assessment of Diet and Physical Activity
    Mingui Sun; Fiscal Year: 2008
    ....
  10. A Unified Sensor System for Ubiquitous Assessment of Diet and Physical Activity
    Mingui Sun; Fiscal Year: 2008
    ....
  11. A Unified Sensor System for Ubiquitous Assessment of Diet and Physical Activity
    Mingui Sun; Fiscal Year: 2007
    ....
  12. A Unified Sensor System for Ubiquitous Assessment of Diet and Physical Activity
    Mingui Sun; Fiscal Year: 2007
    ..abstract_text> ..
  13. Motion Sensor Array for Vestibular-deficient Individuals
    Conrad Wall; Fiscal Year: 2003
    ....
  14. NEURAL CONTROL OF VISUALLY GUIDED EYE MOVEMENTS
    Peter Schiller; Fiscal Year: 2000
    ..The proposed research will increase our knowledge of the neural control of eye and limb movements and will allow us to compare these systems in monkeys and humans. ..
  15. The Role of Areas V1 and V2 in Target Selection
    Peter Schiller; Fiscal Year: 2006
    ..abstract_text> ..
  16. PARALLEL INFORMATION PROCESSING OF THE VISUAL SYSTEM
    Peter Schiller; Fiscal Year: 2001
    ..The proposed work has important clinical relevance as it will serve characterize the functions of various visual cortical areas. ..
  17. Wear, Inflammation and Clinical Performance of Total Disc Replacement
    STEVEN MICHAEL KURTZ; Fiscal Year: 2010
    ..Thus, successful achievement of the proposed research will provide essential information on TDR implant performance and on clinical outcomes, which are needed for informed health care decisions. ..
  18. Motion Sensor Array for Vestibular-deficient Individuals
    Conrad Wall; Fiscal Year: 2002
    ....
  19. Chemokine Directed Cell Trafficking during Continuous Infusion of Wear Particles
    Stuart Goodman; Fiscal Year: 2009
    ..This research will elucidate important mechanisms of particle-induced, chemokine-directed cell trafficking and suggest new treatment strategies. ..
  20. MECHANISMS & PERFORMANCE OF TRACEABLE UHMWPE IMPLANTS
    Steven Kurtz; Fiscal Year: 2003
    ..The purpose of this proposed research is to examine the influence of mechanical degradation after implantation on the clinical performance of metal-backed acetabular components for total hip arthroplasty. ..
  21. PARALLEL INFORMATION PROCESSING OF THE VISUAL SYSTEM
    Peter Schiller; Fiscal Year: 1999
    ..The proposed work has important clinical relevance as it will serve characterize the functions of various visual cortical areas. ..
  22. Prostate Edema in Permanent Interstitial Brachytherapy
    Zhe Chen; Fiscal Year: 2010
    ..The primary objective of this project is to develop a new method to consider the effects of edema in radiation dosimetry and treatment planning so that the efficacy of this therapy can be optimized for each patient. ..
  23. Motion Sensor Array for Vestibular-deficient Individuals
    Conrad Wall; Fiscal Year: 2004
    ....
  24. Mechanics and Performance of Traceable UHMWPE Implants
    Steven Kurtz; Fiscal Year: 2006
    ....
  25. NEURAL CONTROL OF VISUALLY GUIDED EYE MOVEMENTS
    Peter Schiller; Fiscal Year: 1993
    ....
  26. High-Resolution Whole-Breast MRI at 3.0T
    Brian Hargreaves; Fiscal Year: 2008
    ..This research will develop much higher resolution MRI, allowing it to better classify small lesions, prevent unnecessary biopsy, and detect cancer earlier. ..
  27. Motion Sensor Array for Vestibular-deficient Individuals
    Conrad Wall; Fiscal Year: 2005
    ....
  28. Cloning/Gene/Posterior Polymorphous corneal dystrophy
    ANTHONY ALDAVE; Fiscal Year: 2008
    ....
  29. STUDIES OF INTERACTION BETWEEN EYE MOVEMENT AND VISION
    Peter Schiller; Fiscal Year: 1980
    ....
  30. Mechanics and Performance of Traceable UHMWPE Implants
    Steven Kurtz; Fiscal Year: 2008
    ....
  31. Cloning/Gene/Posterior Polymorphous corneal dystrophy
    ANTHONY ALDAVE; Fiscal Year: 2007
    ....
  32. PARALLEL INFORMATION PROCESSING OF THE VISUAL SYSTEM
    Peter Schiller; Fiscal Year: 2002
    ..The proposed work has important clinical relevance as it will serve characterize the functions of various visual cortical areas. ..
  33. NEURAL CONTROL OF VISUALLY GUIDED EYE MOVEMENTS
    Peter Schiller; Fiscal Year: 2001
    ..The proposed research will increase our knowledge of the neural control of eye and limb movements and will allow us to compare these systems in monkeys and humans. ..
  34. Prostate Edema in Permanent Interstitial Brachytherapy
    Zhe Chen; Fiscal Year: 2009
    ..The primary objective of this project is to develop a new method to consider the effects of edema in radiation dosimetry and treatment planning so that the efficacy of this therapy can be optimized for each patient. ..
  35. Prostate Edema in Permanent Interstitial Brachytherapy
    Zhe Chen; Fiscal Year: 2008
    ..The primary objective of this project is to develop a new method to consider the effects of edema in radiation dosimetry and treatment planning so that the efficacy of this therapy can be optimized for each patient. ..
  36. Thromboresistant vascular grafts:heparin-peptidomimetics
    PAUL ZAMORA; Fiscal Year: 2004
    ..abstract_text> ..
  37. The Role of Areas V1 and V2 in Target Selection
    Peter Schiller; Fiscal Year: 2007
    ..abstract_text> ..
  38. Development of semicircular canal prostheses for studies of vestibular plasticity
    DANIEL MERFELD; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  39. Bladder and Sphincter Control after Spinal Cord Injury
    Changfeng Tai; Fiscal Year: 2006
    ..abstract_text> ..
  40. DECODING OF GRAVICEPTOR CUES, INCLUDING ADAPTIVE CHANGES
    DANIEL MERFELD; Fiscal Year: 2003
    ..The experimental specific aims will be addressed by measuring eye movements and perceptual responses. The modeling specific aim will be addressed using numerical computer simulations. ..
  41. GENETIC FACTORS IN KERATOCONUS
    Yaron Rabinowitz; Fiscal Year: 2002
    ....
  42. NEURAL CONTROL OF VISUALLY GUIDED EYE MOVEMENTS
    Peter Schiller; Fiscal Year: 2005
    ..abstract_text> ..
  43. Infusion of Particles at Implant interfeces
    Stuart Goodman; Fiscal Year: 2006
    ..abstract_text> ..
  44. Mechanics and Performance of Traceable UHMWPE Implants
    Steven Kurtz; Fiscal Year: 2005
    ....
  45. CORE - Vision Processies
    Peter Schiller; Fiscal Year: 2008
    ..If funded, this module will provide a central support facility for functional brain imaging by NEI-supported investigators in the BCS department. ..
  46. NEURAL CONTROL OF VISUALLY GUIDED EYE MOVEMENTS
    Peter Schiller; Fiscal Year: 2007
    ..abstract_text> ..
  47. Adaptation to controlled vestibular stimulation
    DANIEL MERFELD; Fiscal Year: 2002
    ..All of these proposed specific aims will be investigated by measuring changes in the vestibulo-ocular responses induced by changes in chronic, patterned, electrical stimulation of the peripheral vestibular system. ..
  48. NEURAL CONTROL OF VISUALLY GUIDED EYE MOVEMENTS
    Peter Schiller; Fiscal Year: 2002
    ..The proposed research will increase our knowledge of the neural control of eye and limb movements and will allow us to compare these systems in monkeys and humans. ..
  49. Adaptation to controlled vestibular stimulation
    DANIEL MERFELD; Fiscal Year: 2003
    ..All of these proposed specific aims will be investigated by measuring changes in the vestibulo-ocular responses induced by changes in chronic, patterned, electrical stimulation of the peripheral vestibular system. ..
  50. Osteolysis and Implant Wear: Biological, Biomedical Engineering, and Surgical Pri
    Stuart Goodman; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  51. The Role of Areas V1 and V2 in Target Selection
    Peter Schiller; Fiscal Year: 2008
    ..abstract_text> ..
  52. GENETIC FACTORS IN KERATOCONUS
    Yaron Rabinowitz; Fiscal Year: 2003
    ....
  53. Chemokine Directed Cell Trafficking during Continuous Infusion of Wear Particles
    Stuart Goodman; Fiscal Year: 2007
    ..This research will elucidate important mechanisms of particle-induced, chemokine-directed cell trafficking and suggest new treatment strategies. ..
  54. BioMEMS Model of Glomerular Function
    WILLIAM FISSELL; Fiscal Year: 2008
    ..Third, HP and s will be measured for the NM-PBM membrane. Fourth, data from (1-3) will be compared with existing predictive models of glomerular function. ..
  55. GENETIC FACTORS IN KERATOCONUS
    Yaron Rabinowitz; Fiscal Year: 2004
    ....
  56. NEURAL CONTROL OF VISUALLY GUIDED EYE MOVEMENTS
    Peter Schiller; Fiscal Year: 2006
    ..abstract_text> ..
  57. GENETIC FACTORS IN KERATOCONUS
    Yaron Rabinowitz; Fiscal Year: 2006
    ....
  58. Mechanics and Performance of Traceable UHMWPE Implants
    Steven Kurtz; Fiscal Year: 2007
    ....
  59. Locomotion Control by Lumbar Spinal Cord Stimulation
    Changfeng Tai; Fiscal Year: 2007
    ..The proposed studies will not only improve our understanding of locomotion control in lumbar spinal cord but also benefit SCI patients. [unreadable] [unreadable]..
  60. PARALLEL INFORMATION PROCESSING OF THE VISUAL SYSTEM
    Peter Schiller; Fiscal Year: 2000
    ..The proposed work has important clinical relevance as it will serve characterize the functions of various visual cortical areas. ..
  61. High-Resolution Whole-Breast MRI at 3.0T
    Brian Hargreaves; Fiscal Year: 2009
    ..This research will develop much higher resolution MRI, allowing it to better classify small lesions, prevent unnecessary biopsy, and detect cancer earlier. ..
  62. Vestibular thresholds, including psychophysical response dynamics
    DANIEL MERFELD; Fiscal Year: 2009
    ..Therefore, the clinical goal for the research proposed herein is to establish precise efficient methods to quantify motion perception in general and, more specifically, to assay perceptual thresholds. ..
  63. High-Resolution Whole-Breast MRI at 3.0T
    Brian Hargreaves; Fiscal Year: 2009
    ..This research will develop much higher resolution MRI, allowing it to better classify small lesions, prevent unnecessary biopsy, and detect cancer earlier. ..
  64. New Strategies to Treat Overactive Bladder
    Changfeng Tai; Fiscal Year: 2010
    ....
  65. Bladder and Sphincter Control after Spinal Cord Injury
    Changfeng Tai; Fiscal Year: 2009
    ..Our new approach also preserves the spinal reflex functions for bowel and sexual organ, and more importantly provides people with SCI the opportunity to benefit from advances in neural regeneration and repair techniques in the future. ..
  66. Adaptation to controlled vestibular stimulation
    DANIEL MERFELD; Fiscal Year: 2001
    ..All of these proposed specific aims will be investigated by measuring changes in the vestibulo-ocular responses induced by changes in chronic, patterned, electrical stimulation of the peripheral vestibular system. ..
  67. NEURAL CONTROL OF VISUALLY GUIDED EYE MOVEMENTS
    Peter Schiller; Fiscal Year: 1992
    ....
  68. DECODING OF GRAVICEPTOR CUES, INCLUDING ADAPTIVE CHANGES
    DANIEL MERFELD; Fiscal Year: 2001
    ..The experimental specific aims will be addressed by measuring eye movements and perceptual responses. The modeling specific aim will be addressed using numerical computer simulations. ..
  69. MECHANISMS & PERFORMANCE OF TRACEABLE UHMWPE IMPLANTS
    Steven Kurtz; Fiscal Year: 2001
    ..The purpose of this proposed research is to examine the influence of mechanical degradation after implantation on the clinical performance of metal-backed acetabular components for total hip arthroplasty. ..
  70. BioMEMS Model of Glomerular Function
    WILLIAM FISSELL; Fiscal Year: 2006
    ..Third, HP and s will be measured for the NM-PBM membrane. Fourth, data from (1-3) will be compared with existing predictive models of glomerular function. ..
  71. Designing a meniscal substitute through an integrated experimental computational
    Suzanne A Maher; Fiscal Year: 2010
    ....
  72. GENETIC FACTORS IN KERATOCONUS
    Yaron Rabinowitz; Fiscal Year: 2001
    ....
  73. Chemokine Directed Cell Trafficking during Continuous Infusion of Wear Particles
    Stuart B Goodman; Fiscal Year: 2010
    ..This research will elucidate important mechanisms of particle-induced, chemokine-directed cell trafficking and suggest new treatment strategies. ..
  74. Vestibular thresholds, including psychophysical response dynamics
    Daniel M Merfeld; Fiscal Year: 2010
    ..Therefore, the clinical goal for the research proposed herein is to establish precise efficient methods to quantify motion perception in general and, more specifically, to assay perceptual thresholds. ..
  75. Decoding graviceptors, sensory and non-sensory influence
    DANIEL MERFELD; Fiscal Year: 2006
    ..3) Investigate the influence of efferent copy and neck receptor cues on the neural processes by which ambiguous otolith cues yield tilt and/or translation responses. [unreadable] [unreadable]..
  76. Bioreactivity Markers in Total Hip Replacments
    Nadim Hallab; Fiscal Year: 2004
    ..Additionally, variable immunologic responses induced by implant degradation products (i.e. lymphocyte response to metal ions and monocyte/macrophage response to particulate debris) will be correlated with the development of osteolysis ..
  77. BION Treatment of Neuromuscular Dysfunction
    Gerald Loeb; Fiscal Year: 2004
    ..abstract_text> ..
  78. Bladder and Sphincter Control after Spinal Cord Injury
    Changfeng Tai; Fiscal Year: 2005
    ..abstract_text> ..
  79. Novel vision tests: data analysis from a RP Lutein trial
    Gislin Dagnelie; Fiscal Year: 2004
    ....
  80. Adaptation to controlled vestibular stimulation
    DANIEL MERFELD; Fiscal Year: 2005
    ..All of these proposed specific aims will be investigated by measuring changes in the vestibulo-ocular responses induced by changes in chronic, patterned, electrical stimulation of the peripheral vestibular system. ..
  81. Development of semicircular canal prostheses for studies of vestibular plasticity
    DANIEL MERFELD; Fiscal Year: 2009
    ..abstract_text> ..
  82. INJECTABLE SENSORS FOR CONTROL OF FES
    Gerald Loeb; Fiscal Year: 2000
    ....
  83. GENETIC FACTORS IN KERATOCONUS
    Yaron Rabinowitz; Fiscal Year: 2009
    ..Ultimately, this work may improve our ability to treat KC and/or prevent the development of KC. ..
  84. STUDIES OF SIMULATED PROSTHETIC VISION
    Gislin Dagnelie; Fiscal Year: 2001
    ..Tasks will be computer-generated, but in years 4 and 5 will include live input from a head-mounted wide-field camera. ..
  85. STUDIES OF SIMULATED PROSTHETIC VISION
    Gislin Dagnelie; Fiscal Year: 2003
    ..Tasks will be computer-generated, but in years 4 and 5 will include live input from a head-mounted wide-field camera. ..