lasers

Summary

Summary: Light Amplification by Stimulated Emission of Radiation. This phenomenon is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the visible, infrared, or ultraviolet regions of the spectrum. They are capable of producing immense heat and power when focused at close range and are used in surgical procedures, in diagnosis, and in physiologic studies. Lasers used at low power, transmitting light not heat, have been used in wound healing and pain control (LASER THERAPY, LOW-LEVEL).

Top Publications

  1. ncbi Various spatiotemporal expression profiles of anther-expressed genes in rice
    Tokunori Hobo
    Bioscience and Biotechnology Center, Nagoya University, Furocho, Chikusa, Nagoya, 464 8601 Japan
    Plant Cell Physiol 49:1417-28. 2008
  2. ncbi Gene discovery and annotation using LCM-454 transcriptome sequencing
    Scott J Emrich
    Bioinformatics and Computational Biology Graduate Program, Iowa State University, Ames, IA 50010, USA
    Genome Res 17:69-73. 2007
  3. ncbi PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility
    Camille Godon
    Institut Curie, Centre de Recherche INSERM, U612, Institut Curie, Bât 110 112, Centre Universitaire, F 91405 Orsay, France
    Nucleic Acids Res 36:4454-64. 2008
  4. ncbi Nociceptive laser-evoked brain potentials do not reflect nociceptive-specific neural activity
    A Mouraux
    Department of Clinical Neurology, University of Oxford, OX1 3QX Oxford, United Kingdom
    J Neurophysiol 101:3258-69. 2009
  5. ncbi Megabase chromatin domains involved in DNA double-strand breaks in vivo
    E P Rogakou
    Laboratory of Molecular Pharmacology, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Cell Biol 146:905-16. 1999
  6. ncbi Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV
    S R Singh
    Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE, USA
    Gene Ther 16:645-59. 2009
  7. ncbi Determinants of laser-evoked EEG responses: pain perception or stimulus saliency?
    G D Iannetti
    Department of Physiology, Anatomy, and Genetics, University of Oxford, South Parks Road, OX1 3QX, Oxford, UK
    J Neurophysiol 100:815-28. 2008
  8. ncbi Stromal gene expression predicts clinical outcome in breast cancer
    Greg Finak
    McGill Centre for Bioinformatics, 3775 University Street, McGill University, Quebec H3A 2B4, Canada
    Nat Med 14:518-27. 2008
  9. ncbi Functional magnetic resonance imaging detects activation of the visual association cortex during laser acupuncture of the foot in humans
    Christian M Siedentopf
    Department of Radiology II, University Hospital of Innsbruck, Innsbruck, Austria
    Neurosci Lett 327:53-6. 2002
  10. ncbi Modulation of pain ratings by expectation and uncertainty: Behavioral characteristics and anticipatory neural correlates
    Christopher A Brown
    Human Pain Research Group, Clinical Sciences Building, Hope Hospital, Salford M6 8HD, United Kingdom
    Pain 135:240-50. 2008

Research Grants

  1. Short Wavelength UV Sources for Treatment of Psoriasis
    JOSEPH SMART; Fiscal Year: 2006
  2. Port wine stain treatment for infants and young children
    Guillermo Aguilar; Fiscal Year: 2006
  3. FACSVantage SE Upgrade
    RAYMOND HESTER; Fiscal Year: 2004
  4. Structure and Biomechanics of the Human Optic Nerve Head
    Donald J Brown; Fiscal Year: 2010
  5. Dynamic Evaluation of Coronary Intervention
    Kevin Kip; Fiscal Year: 2006
  6. ULTRAVIOLET LIGHT INDUCED PHENOMENA IN BIOMEMBRANES
    IRENE KOCHEVAR; Fiscal Year: 1999
  7. Oxide Glass Fiber Optimized for Short Pulse IR Lasers
    Danh Tran; Fiscal Year: 2006
  8. Laser Ablation of Dental Hard Tissues
    Daniel Fried; Fiscal Year: 2006
  9. 2007 Electron Distribution & Chemical Bonding Gordon Research Conference
    Carlo Gatti; Fiscal Year: 2007
  10. Optical probes for controlling cellular function
    Graham Ellis Davies; Fiscal Year: 2010

Detail Information

Publications202 found, 100 shown here

  1. ncbi Various spatiotemporal expression profiles of anther-expressed genes in rice
    Tokunori Hobo
    Bioscience and Biotechnology Center, Nagoya University, Furocho, Chikusa, Nagoya, 464 8601 Japan
    Plant Cell Physiol 49:1417-28. 2008
    ....
  2. ncbi Gene discovery and annotation using LCM-454 transcriptome sequencing
    Scott J Emrich
    Bioinformatics and Computational Biology Graduate Program, Iowa State University, Ames, IA 50010, USA
    Genome Res 17:69-73. 2007
    ..We conclude that the coupling of LCM and 454 sequencing technologies facilitates the discovery of rare, possibly cell-type-specific transcripts...
  3. ncbi PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility
    Camille Godon
    Institut Curie, Centre de Recherche INSERM, U612, Institut Curie, Bât 110 112, Centre Universitaire, F 91405 Orsay, France
    Nucleic Acids Res 36:4454-64. 2008
    ..PARP-1 inhibition and deletion thus have different outcomes in terms of SSBR and radiosensitivity...
  4. ncbi Nociceptive laser-evoked brain potentials do not reflect nociceptive-specific neural activity
    A Mouraux
    Department of Clinical Neurology, University of Oxford, OX1 3QX Oxford, United Kingdom
    J Neurophysiol 101:3258-69. 2009
    ....
  5. ncbi Megabase chromatin domains involved in DNA double-strand breaks in vivo
    E P Rogakou
    Laboratory of Molecular Pharmacology, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Cell Biol 146:905-16. 1999
    ..The results further suggest the possible existence of units of higher order chromatin structure involved in monitoring DNA integrity...
  6. ncbi Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV
    S R Singh
    Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE, USA
    Gene Ther 16:645-59. 2009
    ..Thus, surface-functionalized nanoparticles allow targeted gene delivery to the neovascular eye on intravenous administration and inhibit the progression of laser-induced CNV in a rodent model...
  7. ncbi Determinants of laser-evoked EEG responses: pain perception or stimulus saliency?
    G D Iannetti
    Department of Physiology, Anatomy, and Genetics, University of Oxford, South Parks Road, OX1 3QX, Oxford, UK
    J Neurophysiol 100:815-28. 2008
    ..e., its ability to capture attention). Therefore laser-evoked EEG responses represent an indirect readout of the function of the nociceptive system...
  8. ncbi Stromal gene expression predicts clinical outcome in breast cancer
    Greg Finak
    McGill Centre for Bioinformatics, 3775 University Street, McGill University, Quebec H3A 2B4, Canada
    Nat Med 14:518-27. 2008
    ..Genes represented in the SDPP reveal the strong prognostic capacity of differential immune responses as well as angiogenic and hypoxic responses, highlighting the importance of stromal biology in tumor progression...
  9. ncbi Functional magnetic resonance imaging detects activation of the visual association cortex during laser acupuncture of the foot in humans
    Christian M Siedentopf
    Department of Radiology II, University Hospital of Innsbruck, Innsbruck, Austria
    Neurosci Lett 327:53-6. 2002
    ..These results indicate that fMRI has the potential to elucidate effects of acupuncture on brain activity...
  10. ncbi Modulation of pain ratings by expectation and uncertainty: Behavioral characteristics and anticipatory neural correlates
    Christopher A Brown
    Human Pain Research Group, Clinical Sciences Building, Hope Hospital, Salford M6 8HD, United Kingdom
    Pain 135:240-50. 2008
    ..This suggests that biasing of pain reports and LEPs by expectation involves temporally precise activity in specific cortical networks...
  11. ncbi Laser assisted bioprinting of engineered tissue with high cell density and microscale organization
    Bertrand Guillotin
    Universite Victor Segalen Bordeaux 2, Bordeaux Cedex, France
    Biomaterials 31:7250-6. 2010
    ..We have successfully implemented such a cell printing precision to print miniaturized tissue like layouts with de novo high cell density and micro scale organization...
  12. ncbi Evidence of a specific spinal pathway for the sense of warmth in humans
    G D Iannetti
    Dipartimento Scienze Neurologiche, , 00185 Rome, Italy
    J Neurophysiol 89:562-70. 2003
    ..Our results support the existence of slow-conducting second-order neurons specific for the sense of warmth...
  13. ncbi Dissociable neural responses related to pain intensity, stimulus intensity, and stimulus awareness within the anterior cingulate cortex: a parametric single-trial laser functional magnetic resonance imaging study
    Christian Buchel
    Cognitive Neuroscience Laboratory, Department of Neurology, and Department of Physiology, Hamburg University Medical School, Hamburg, D 20246 Germany
    J Neurosci 22:970-6. 2002
    ..Stimulus-related activations were all located adjacent to the cingulate motor area, highlighting the strategic link of stimulus processing and response generation in the posterior ACC...
  14. ncbi Neurons regulating the duration of forward locomotion in Caenorhabditis elegans
    Tokumitsu Wakabayashi
    Laboratory of Bioscience, Faculty of Engineering, Iwate University, 4-3-5 Ueda, Morioka 020-8551, Japan
    Neurosci Res 50:103-11. 2004
    ..Loss of any one of these neurons altered the locomotory behavior...
  15. ncbi Automatic detection of spermatozoa for laser capture microdissection
    Mado Vandewoestyne
    Laboratory for Pharmaceutical Biotechnology, Ghent University, Harelbekestraat 72, 9000, Ghent, Belgium
    Int J Legal Med 123:169-75. 2009
    ..Robust DNA profiles without allelic dropout could be obtained from as little as 30 spermatozoa recovered from postcoital samples, showing that the staining had no significant influence on DNA recovery...
  16. ncbi Intraocular multiphoton microscopy with subcellular spatial resolution by infrared femtosecond lasers
    Bao-gui Wang
    Lasermicroscopy Research, Institute of Microscopic Anatomy (Anatomy II, University of Jena, Teichgraben str. 7, 07743, Jena, Germany
    Histochem Cell Biol 126:507-15. 2006
    ..based on the multiphoton microscopy (MPM) with different excitation wavelengths of infrared femtosecond (fs) lasers. The multiphoton nonlinear processing including two-photon fluorescence (2PF) and second harmonic generation (SHG) ..
  17. ncbi Amplitudes of laser evoked potential recorded from primary somatosensory, parasylvian and medial frontal cortex are graded with stimulus intensity
    S Ohara
    Department of Neurosurgery, Johns Hopkins Hospital, Meyer Building 8-181, 600 North Wolfe Street, Baltimore, MD 21287-7713, USA
    Pain 110:318-28. 2004
    ....
  18. ncbi A new insight into the cellular regulation of aqueous outflow: how trabecular meshwork endothelial cells drive a mechanism that regulates the permeability of Schlemm's canal endothelial cells
    J A Alvarado
    University of California San Francisco, Department of Ophthalmology 10 Koret Way San Francisco, CA 94143 0730, USA
    Br J Ophthalmol 89:1500-5. 2005
    ..To test the hypothesis that trabecular meshwork endothelial cells (TMEs) increase the permeability of Schlemm's canal endothelial cells (SCEs) by actively releasing ligands that modulate the barrier properties of SCEs...
  19. ncbi Quantitative RT-PCR gene expression analysis of laser microdissected tissue samples
    Heidi S Erickson
    Pathogenetics Unit, Laboratory of Pathology and Urologic Oncology Branch, National Cancer Institute, NIH, Bethesda, MD, USA
    Nat Protoc 4:902-22. 2009
    ..The entire protocol from tissue microdissection through qRT-PCR analysis requires approximately 16 h...
  20. ncbi Laser microdissection separation of pure spermatozoa from epithelial cells for short tandem repeat analysis
    Christine T Sanders
    Department of Neuroscience, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA
    J Forensic Sci 51:748-57. 2006
    ..This report describes an efficient, low-manipulation LMD method for the efficient separation of spermatozoa from two-donor sperm/epithelial cell mixtures...
  21. ncbi Separated transcriptomes of male gametophyte and tapetum in rice: validity of a laser microdissection (LM) microarray
    Keita Suwabe
    Graduate School of Life Sciences, Tohoku University, Sendai, 980 8577 Japan
    Plant Cell Physiol 49:1407-16. 2008
    ..These results indicate that the 44K LM-microarray is a reliable tool to analyze the gene expression profiles of two important cell types in the anther, the microspore/pollen and tapetum...
  22. ncbi Identification and isolation of male cells using fluorescence in situ hybridisation and laser microdissection, for use in the investigation of sexual assault
    Caroline Murray
    The Forensic Science Service, Trident Court, 2960 Solihull Parkway, Birmingham Business Park, Solihull B37 7YN, UK
    Forensic Sci Int Genet 1:247-52. 2007
    ..Useful DNA profiles were generated from samples taken up to 24h after intercourse...
  23. ncbi Gene expression profiling of gastric cancer by microarray combined with laser capture microdissection
    Ming-Shiang Wu
    Department of Internal Medicine and Primary Care Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan, China
    World J Gastroenterol 11:7405-12. 2005
    ..The new molecular classification and the identified novel genes in gastric carcinogenesis deserve further investigations to elucidate their clinicopathological significance...
  24. ncbi Evidence-based review of hair removal using lasers and light sources
    M Haedersdal
    Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark
    J Eur Acad Dermatol Venereol 20:9-20. 2006
    ..Unwanted hair growth remains a therapeutic challenge and there is a considerable need for an effective and safe treatment modality...
  25. ncbi Single-cell printing to form three-dimensional lines of olfactory ensheathing cells
    Christina M Othon
    Naval Research Laboratory Code 6113, 4555 Overlook Ave SW, Washington, DC 20375, USA
    Biomed Mater 3:034101. 2008
    ..In addition, these cell-printed scaffolds may provide an alternative for spinal cord repair studies, as the single-cell patterns formed here are on relevant size scales for neurite outgrowth...
  26. ncbi Therapeutic applications of lasers in urology: an update
    Nathaniel M Fried
    Johns Hopkins University School of Medicine, James Buchanan Brady Urological Institute, Biophotonics Laboratory, Baltimore, MD 21224, USA
    Expert Rev Med Devices 3:81-94. 2006
    There has been renewed interest in the use of lasers for minimally invasive treatment of urologic diseases in recent years...
  27. ncbi Laser printing of cells into 3D scaffolds
    A Ovsianikov
    Nanotechnology Department, Laser Zentrum Hannover eV, Hollerithallee 8, 30419 Hannover, Germany
    Biofabrication 2:014104. 2010
    ..Combination of LIFT and 2PP provides a route for the realization of 3D multicellular tissue constructs and artificial ECM engineered on the microscale...
  28. ncbi Laser printing of skin cells and human stem cells
    Lothar Koch
    Department of Nanotechnology, Laser Zentrum Hannover e V, Hannover, Germany
    Tissue Eng Part C Methods 16:847-54. 2010
    ..This study demonstrates LIFT as a suitable technique for unharmed computer-controlled positioning of different cell types and a promising tool for future applications in the ex vivo generation of tissue replacements...
  29. ncbi Development of human umbilical vein endothelial cell (HUVEC) and human umbilical vein smooth muscle cell (HUVSMC) branch/stem structures on hydrogel layers via biological laser printing (BioLP)
    P K Wu
    Department of Physics, Southern Oregon University, Ashland, OR 97520, USA
    Biofabrication 2:014111. 2010
    ..Our results indicate that it is possible to direct the formation and growth of lumen and lumen network using BioLP...
  30. ncbi Altered nociceptive C fibre input to primary somatosensory cortex in an animal model of hyperalgesia
    Tanja Jensen
    Neuronano Research Center, Section for Neuroscience, Lund University, BMC F10, SE 221 84 Lund, Sweden
    Eur J Pain 15:368-75. 2011
    ..Tactile evoked potentials were not affected by UV-B irradiation or tramadol. We conclude that altered sensory processing related to hyperalgesia is reflected in altered LCEPs in SI cortex...
  31. ncbi Fast STED microscopy with continuous wave fiber lasers
    Gael Moneron
    Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
    Opt Express 18:1302-9. 2010
    ..in the visible range using for resolution enhancement compact, low cost and turn-key continuous wave (CW) fiber lasers emitting at 592 nm...
  32. ncbi Laser-based direct-write techniques for cell printing
    Nathan R Schiele
    Biomedical Engineering Department, Rensselaer Polytechnic Institute, Troy, NY, USA
    Biofabrication 2:032001. 2010
    ..A particular focus is paid to process dynamics modeling and process-induced cell injury during laser-based cell direct writing...
  33. ncbi Sources of cortical responses to painful CO(2) laser skin stimulation of the hand and foot in the human brain
    M Valeriani
    Department of Neurology, Universita Cattolica del Sacro Cuore, L go A Gemelli 8, 00168, Rome, Italy
    Clin Neurophysiol 111:1103-12. 2000
    ..To investigate whether the same dipolar model could explain the scalp CO(2) laser evoked potential (LEP) distribution after either hand or foot skin stimulation...
  34. ncbi Bursts of 15-30 Hz oscillations following noxious laser stimulus originate in posterior cingulate cortex
    Andrej Stancak
    Charles University Prague, Department of Normal, Pathological and Clinical Physiology, Third Faculty of Medicine, Ke Karlovu 4, 120 00 Prague 2, Czech Republic
    Brain Res 1317:69-79. 2010
    ..The poststimulus increases of 15-30 Hz oscillations may stand for transient cortical inhibition possibly aiding temporary suppression of motor programs that have been primed by noxious stimulation...
  35. ncbi Mechanisms of pulsed laser ablation of biological tissues
    Alfred Vogel
    , Peter-Monnik-Weg 4, , Germany
    Chem Rev 103:577-644. 2003
  36. ncbi Fundamentals of dental lasers: science and instruments
    Donald J Coluzzi
    Dent Clin North Am 48:751-70, v. 2004
    ..Various dental tissues have unique interactions with laser light, and the principles of safe and effective use of this unique instrument are presented. Each wavelength's applications for treatment are outlined...
  37. ncbi Clinical comparison of four hair removal lasers and light sources
    Snehal P Amin
    Skin Laser and Surgery Specialists of NY and NJ, and the Mount Sinai School of Medicine, New York, NY 10022, USA
    J Cosmet Laser Ther 8:65-8. 2006
    ..CONCLUSION: Although hair removal with commonly used systems is, as expected, highly effective, treatment with light-based devices can cause less pain, yet show efficacy similar to laser systems...
  38. ncbi Single gallium nitride nanowire lasers
    Justin C Johnson
    Department of Chemistry, University of California, Berkeley, California 94720-1460, USA
    Nat Mater 1:106-10. 2002
    ..much practical interest, because it is widely used in electrically pumped ultraviolet-blue light-emitting diodes, lasers and photodetectors...
  39. ncbi The use of lasers in dentistry: principles of operation and clinical applications
    Adam Stabholz
    Department of Endodontics, Hebrew University-Hadassah School of Dental Medicine, Jerusalem, Israel
    Compend Contin Educ Dent 24:935-48; quiz 949. 2003
    ..Clinical applications of the CO2 and diode lasers on soft tissues, particularly in the fields of oral and maxillofacial surgery and perodontics, are explained...
  40. ncbi Comparison of laser-assisted hatching and acidified Tyrode's hatching by evaluation of blastocyst development rates in sibling embryos: a prospective randomized trial
    Amy E Jones
    Reproductive Biology Associates, Atlanta, Georgia, USA
    Fertil Steril 85:487-91. 2006
    ..To assess two zona drilling methods in terms of blastocyst development rates using sister embryos...
  41. ncbi Effects of acupressure, manual acupuncture and Laserneedle acupuncture on EEG bispectral index and spectral edge frequency in healthy volunteers
    G Litscher
    University of Graz, Department of Biomedical Engineering and Research in Anesthesia and Intensive Care, Graz, Austria
    Eur J Anaesthesiol 21:13-9. 2004
    ....
  42. ncbi A comparison of four different techniques of assisted hatching
    Basak Balaban
    Assisted Reproduction Unit, American Hospital of Istanbul, Istanbul, Turkey
    Hum Reprod 17:1239-43. 2002
    ..Mean number of embryos transferred, implantation rate, clinical pregnancy rate, and abortion rates were likewise similar. CONCLUSIONS: Selective AH using four different methods yields similar implantation and pregnancy rates...
  43. ncbi Effects of acute stressors on nociception, adrenocortical responses and behavior of dairy cows
    Mette S Herskin
    Danish Institute of Agricultural Sciences, Department of Animal Health and Welfare, Research Center Foulum, P O Box 50, DK 8830 Tjele, Denmark
    Physiol Behav 83:411-20. 2004
    ....
  44. ncbi A comparison between quarter, partial and total laser assisted hatching in selected infertility patients
    E Mantoudis
    London Gynaecology and Fertility Centre, Cozens House, 112a Harley Street, London, W1G 7JH, UK
    Hum Reprod 16:2182-6. 2001
    ..The object of this study was to evaluate the efficacy of laser assisted hatching (LAH) of embryos on implantation and pregnancy rates of a selected group of infertility patients...
  45. ncbi Implantation failures: success of assisted hatching with quarter-laser zona thinning
    C G Petersen
    , , 1500-CEP 14085-100, , SP-Brazil
    Reprod Biomed Online 10:224-9. 2005
    ..The data demonstrate that qLZT-AH is an effective strategy for improving the implantation of embryos in patients with repeated implantation failures...
  46. ncbi Survival and proliferative ability of various living cell types after laser-induced forward transfer
    Béla Hopp
    Research Group on Laser Physics, Hungarian Academy of Sciences and University of Szeged, Szeged, Hungary
    Tissue Eng 11:1817-23. 2005
    ..These results suggest that the absorbing film-assisted laser-induced forward transfer technique appears to be suitable for several potential applications in tissue engineering and the biomedical tissue repair technologies...
  47. ncbi Comparison of histologic, biochemical, and mechanical properties of murine skin treated with the 1064-nm and 1320-nm Nd:YAG lasers
    Yong-Yan Dang
    Institute for Laser Medicine and Biophotonics, Shanghai Jiaotong University, Shanghai, China
    Exp Dermatol 14:876-82. 2005
    ..It appeared that photo-mechanic reaction could cause more collagen type III synthesis whereas the photo-thermal effect was in favor of the formation of collagen type I...
  48. ncbi Proteome analysis of human gastric cardia adenocarcinoma by laser capture microdissection
    Yan Cheng
    Department of Gastroenterology, The Second Affiliated Hospital, Xi an Jiaotong University, Xi an, China
    BMC Cancer 7:191. 2007
    ..The incidence of gastric cardiac adenocarcinoma (GCA) has been increasing in the past two decades in China, but the molecular changes relating to carcinogenesis have not been well characterised...
  49. ncbi Opioid peptides and behavioral and physiological responses of dairy cows to social isolation in unfamiliar surroundings
    J Rushen
    Dairy and Swine Research and Development Center, Agriculture and Agri Food Canada, Lennoxville, Quebec
    J Anim Sci 77:2918-24. 1999
    ..Isolation also reduces pain sensitivity, suggesting a stress-induced analgesia. However, we found no evidence that naloxone-sensitive opioid receptors were involved in these responses...
  50. ncbi An automated two-dimensional optical force clamp for single molecule studies
    Matthew J Lang
    Department of Biological Sciences, Stanford University, Stanford, California 94305-5020, USA
    Biophys J 83:491-501. 2002
    ..We present details of force clamp operation and preliminary data showing kinesin motor movement subject to diagonal and forward loads...
  51. ncbi Comparison of effects of zona drilling by non-contact infrared laser or acid Tyrode's on the development of human biopsied embryos as revealed by blastomere viability, cytoskeletal analysis and molecular cytogenetics
    Katerina Chatzimeletiou
    The London Bridge Fertility, Gynaecology and Genetics Centre, London SE1 9RY, UK
    Reprod Biomed Online 11:697-710. 2005
    ..Acid Tyrode's drilling can also cause damage, and tended to retard blastocyst development...
  52. ncbi Measurement of skin temperature after infrared laser stimulation
    M Leandri
    Interuniversity Centre for Pain Neurophysiology, University of Genova, Via Dodecaneso 35, 16146 Genova, Italy
    Neurophysiol Clin 36:207-18. 2006
    OBJECTIVES: Several types of lasers are available for eliciting laser evoked responses (LEPs)...
  53. ncbi A laser-based method to measure thermal nociception in dairy cows: short-term repeatability and effects of power output and skin condition
    M S Herskin
    Danish Institute of Agricultural Sciences, Department of Animal Health and Welfare, Research Center Foulum, DK 8830 Tjele, Denmark
    J Anim Sci 81:945-54. 2003
    ..The fact that repeated testing in itself at t = 15 min led to increased responses means that the test will be a conservative measure of stress-induced analgesia...
  54. ncbi Jet-based methods to print living cells
    Bradley R Ringeisen
    Chemical Dynamics and Diagnostics Branch, U S Naval Research Laboratory, Washington, DC, USA
    Biotechnol J 1:930-48. 2006
    ..We conclude the review by comparing and contrasting the different jet-based techniques, while providing a map for future experiments that could lead to significant advances in the field of tissue engineering...
  55. ncbi fMRI reveals how pain modulates visual object processing in the ventral visual stream
    Ulrike Bingel
    NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Germany
    Neuron 55:157-67. 2007
    ....
  56. ncbi Fluorescence-aided molecule sorting: analysis of structure and interactions by alternating-laser excitation of single molecules
    Achillefs N Kapanidis
    Department of Chemistry and Biochemistry, University of California, 607 Charles E Young Drive East, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 101:8936-41. 2004
    ....
  57. ncbi Fluorescence nanoscopy with optical sectioning by two-photon induced molecular switching using continuous-wave lasers
    Jonas Fölling
    Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany
    Chemphyschem 9:321-6. 2008
    ..Future synthesis of similar compounds holds great promise for cost-effective fluorescence nanoscopy with noninvasive optical sectioning...
  58. ncbi Dynamic processing of nociception in cortical network in conscious rats: a laser-evoked field potential study
    Zhi Mei Qiao
    Neuroscience Research Institute, Peking University, Beijing, China
    Cell Mol Neurobiol 28:671-87. 2008
    ..4) Characterization of the spatio-temporal responses to noxious laser stimulation may be a valuable model for the study of pain mechanisms and for the assessment of analgesia...
  59. ncbi Measuring physical traits of primates remotely: the use of parallel lasers
    Jessica M Rothman
    McGill School of Environment, McGill University, Montreal, Que, Canada
    Am J Primatol 70:1191-5. 2008
    ..Two parallel lasers separated by a known distance (4 cm) and mounted onto a digital camera are projected onto an animal...
  60. ncbi Combining laser capture microdissection and proteomics techniques
    Dana Mustafa
    Department of Pathology, Josephine Nefkens Institute, Erasmus Medical Center, Rotterdam, The Netherlands
    Methods Mol Biol 428:159-78. 2008
    ..Obviously, validation of result is essential. The present review describes and discusses the various methods developed to target cell populations of interest by laser microdissection, followed by analysis of their proteome...
  61. ncbi Rat models for glaucoma research
    John C Morrison
    Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA
    Prog Brain Res 173:285-301. 2008
    ..Continued use of these models will lead to a better understanding of cellular mechanisms of pressure-induced optic nerve damage and POAG...
  62. ncbi Use of laser microdissection greatly improves the recovery of DNA from sperm on microscope slides
    K Elliott
    Research and Development, The Forensic Science Service, Trident Court, Solihull Parkway, Birmingham Business Park, SolihullB37 7YN, UK
    Forensic Sci Int 137:28-36. 2003
    ....
  63. ncbi Two-photon excitation fluorescence bioassays
    Pekka Hanninen
    Department of Cell Biology and Anatomy, Laboratory of Biophysics, University of Turku, 20014 Turku, Finland
    Ann N Y Acad Sci 1130:320-6. 2008
    ..This article focuses on the development path of two-photon excitation-based assay system...
  64. ncbi [Study on a sensitive setup of capillary electrophoresis with laser induced fluorescence detector and its application]
    Yuan-qian Li
    Department of Sanitary Technology, West China School of Public Health, Sichuan University, Chengdu 610041, China
    Sichuan Da Xue Xue Bao Yi Xue Ban 35:103-6. 2004
    ..It can be applied as a more effective means for analysis of DNA fragments and protein...
  65. ncbi Capillary electrophoresis with laser-induced fluorescence detection as a tool for enzyme characterization and inhibitor screening
    Dan Ning Liu
    School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China
    Anal Sci 24:333-7. 2008
    ..It can be concluded that this method is suitable for high throughput screening (HTS) assays because it can deliver fast, sensitive, quantitative, and reliable results...
  66. ncbi Determination of vigabatrin in human plasma by means of CE with LIF detection
    Alessandro Musenga
    Pharmaco Toxicological Analysis Laboratory, Department of Pharmaceutical Sciences, Alma Mater Studiorum University of Bologna, Via Belmeloro 6, I 40126 Bologna, Italy
    Electrophoresis 28:3535-41. 2007
    ..7% and accuracy (recovery) was between 97.0 and 101.6%. The method has been successfully applied to the analysis of VGB in plasma of epileptic patients undergoing therapy with the drug...
  67. ncbi Laser-induced fluorescence detection on multichannel electrophoretic microchips using microprocessor-embedded acousto-optic laser beam scanning
    Zhili Huang
    Department of Chemistry, University of Virginia, Charlottesville 22901, USA
    IEEE Trans Biomed Eng 49:859-66. 2002
    ....
  68. ncbi Surface-enhanced Raman and fluorescence joint analysis of soil humic acids
    G Corrado
    Dipartimento di Scienze e Tecnologie Agroambientali, Universita degli Studi di Bologna, V le Fanin 40, Bologna 40126, Italy
    Anal Chim Acta 616:69-77. 2008
    ....
  69. ncbi Lasing droplets in a microfabricated channel
    Melikhan Tanyeri
    Department of Physics, University of California, Davis, One Shields Avenue, Davis, California 95616, USA
    Opt Lett 32:2529-31. 2007
    ..Spectra from the droplets exhibit morphology-dependent resonances that are redshifted relative to the bulk fluorescence emission from the dyes. The dependence of resonant peak intensities on the pump beam power is nonlinear...
  70. ncbi Terahertz pulse transmission in plastic photonic crystal fibres
    H Park
    Department of Electrical and Computer Engineering, Pohang University of Science and Technology, San 31, Hyoja-dong, Nam-gu, Pohang, Kyungbuk 790-784, Korea
    Phys Med Biol 47:3765-9. 2002
    ..1-3 THz. Such PPCFs have the promise of low loss, mechanically flexible interconnect channels for compact THz devices and systems...
  71. ncbi Laser backscattering and transillumination imaging of human tissues and their equivalent phantoms
    R Srinivasan
    Biomedical Engineering Division, Indian Institute of Technology. Madras, Chennai 600036, India
    IEEE Trans Biomed Eng 50:724-30. 2003
    ..profiles from a human forearm and transmission profiles through a human thumb, of red and near-infrared lasers, were determined...
  72. ncbi Grating-less, fiber-based oscillator that generates 25 nJ pulses at 80 MHz, compressible to 150 fs
    J An
    Department of Physics, Pohang University of Science and Technology, Pohang, South Korea, 790 784
    Opt Lett 32:2010-2. 2007
    ..This design, which we believe to be the first of its kind, produces 25 nJ pulses at 80 MHz with the pulses compressible to 150 fs. The pulses appear to be self-similar and initial data imply that their energy is further scalable...
  73. ncbi Fourier fluorescence spectrometer for excitation emission matrix measurement
    Leilei Peng
    Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 55 Fruit Street, BAR 708, Massachusetts 02114, USA
    Opt Express 16:10493-500. 2008
    ..The system provides a wide spectral range, adjustable spectral resolution, and fast EEM acquisition speed, which allows EEM's to be acquired in 40 seconds at a spectral resolution of 81-cm-1...
  74. ncbi Performance of a new laser fluorescence device for the detection of occlusal caries in vitro
    A Lussi
    Department of Operative, Preventive and Paediatric Dentistry, School of Dental Medicine, University of Berne, Switzerland
    J Dent 34:467-71. 2006
    ..The new device comes with two different sapphire fibre tips: a cylindrical tip and a conical tip. The two new sapphire fibre tips were used and compared with the tip currently available with DIAGNOdent (DD)...
  75. ncbi Highly sensitive detection of optical discrete absorption and resonance fluorescence of fused silica in the far ultraviolet
    Fuat Bayrakceken
    Department of Electrical and Electronics Engineering, Yeditepe University, Kayiş daği, Istanbul 81120, Turkey
    Spectrochim Acta A Mol Biomol Spectrosc 60:923-5. 2004
    ..in optoelectronics and flash (laser flash spectroscopy laboratory use), for optical fibers and power optics and lasers. An ultraviolet discrete absorption spectra and resonance coherent fluorescence were recorded photographically ..
  76. ncbi Automated detection of fecal contamination of apples by multispectral laser-induced fluorescence imaging
    Alan M Lefcourt
    Instrumentation and Sensing Laboratory, U S Department of Agricultural Research Service, Building 303, Powder Mill Road, Beltsville, Maryland 20705, USA
    Appl Opt 42:3935-43. 2003
    ..This technology may encourage development of commercial systems for detecting fecal contamination of apples...
  77. ncbi Compact detector for proteins based on two-photon excitation of native fluorescence
    Uchenna P Paul
    Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah 84602, USA
    Anal Chem 77:3690-3. 2005
    ..Detection limits for phenylalanine, tyrosine, and tryptophan were 62 microM, 2.0 microM, and 470 nM, respectively, in a volume of 3 fL. The detection limit for a test protein, bovine serum albumin, was 130 nM...
  78. ncbi Gating a channel photomultiplier with a fast high-voltage switch: reduction of afterpulse rates in a laser-induced fluorescence instrument for measurement of atmospheric OH radical concentrations
    Yugo Kanaya
    Frontier Research Center for Global Change, Japan Agency for Marine Earth Science and Technology, 3173 25 Showa machi, Kanazawa Ku, Yokohoma, Kanagawa 236 0001, Japan
    Appl Opt 45:1254-9. 2006
    ....
  79. ncbi In situ pressure calibration for piston cylinder cells via ruby fluorescence with fiber optics
    Kazuko Koyama-Nakazawa
    Institute for Solid State Physics, University of Tokyo, 5 1 5 Kashiwanoha, Kashiwa, Chiba 277 8581, Japan
    Rev Sci Instrum 78:066109. 2007
    ..Because of these advantages, three fibers were simultaneously introduced in the sample space at the same time, and pressure distribution was measured for Fluorinert (FC70:FC77=1:1), Daphne oil 7373, and Fomblin oil (YHVAC 13014)...
  80. ncbi Instrumentation for measuring fluorescence cross sections from airborne microsized particles
    A Manninen
    Department of Physics, Tampere University of Technology, Tampere, Finland
    Appl Opt 47:110-5. 2008
    ..The dependence of the fluorescence on the excitation wavelength is studied and fluorescence cross sections are estimated. Agreement between the measured fluorescence data and the literature data for riboflavin is observed...
  81. ncbi Ability of laser fluorescence device associated with fluorescent dyes in detecting and quantifying early smooth surface caries lesions
    Fausto Medeiros Mendes
    Universidade de Sao Paulo, Faculdade de Odontologia, Departamento de Odontopediatria, Av Lineu Prestes, 2227 CEP 05508 900, Sao Paulo, SP, Brazil
    J Biomed Opt 11:024007. 2006
    ..Better performance is achieved with LF TMPyP for all parameters than with LF alone. LF PPIX does not present good results. In conclusion, LF TMPyP provides good performance in detecting and quantifying very early enamel caries lesions...
  82. ncbi Fluorescence rejection in resonance Raman spectroscopy using a picosecond-gated intensified charge-coupled device camera
    Evtim V Efremov
    Department of Analytical Chemistry and Applied Spectroscopy, Laser Centre Vrije Universiteit Amsterdam, The Netherlands
    Appl Spectrosc 61:571-8. 2007
    ..Furthermore, good time-gated RRS spectra are shown for a strongly fluorescent flavoprotein (lambda(exc) = 405 nm). Advantages and disadvantages of this approach for RRS are discussed...
  83. ncbi Fast fluorescence laser tracking microrheometry. I: instrument development
    Maxine Jonas
    Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Biophys J 94:1459-69. 2008
    ..An upcoming companion article will illustrate the use of FLTM in studying the solid-like versus liquid-like rheological properties of fibroblast cytoskeletons in living biological samples...
  84. ncbi Distance and angular dependence of intensity ratios in laser-induced autofluorescence techniques
    L C Kwek
    National Institute of Education, Nanyang Technological University, 1 Nanyang Walk, Singapore 639798
    Med Phys 31:1072-5. 2004
    ..However, we find substantial fluctuation in the intensities of peaks for changing distances. These fluctuations can be eliminated by considering the ratio of the intensities from two spectral lines...
  85. ncbi Multiple sampling in single-cell enzyme assays using CE-laser-induced fluorescence to monitor reaction progress
    Glen K Shoemaker
    Chemistry Department, University of Alberta, Edmonton, Alberta, Canada T6G 2G2
    Anal Chem 77:3132-7. 2005
    ..Embryos were simultaneously assayed for a second enzyme, beta-galactosidase, illustrating that the mutants were viable except for their lack of alpha-glucosidase I activity...
  86. ncbi Sheath-flow cuvette for high-sensitivity laser-induced fluorescence detection in capillary electrophoresis
    Kimia Sobhani
    Department of Chemistry, University of Washington, Box 351700, Seattle, Washington 98195 1700, USA
    Appl Spectrosc 61:777-9. 2007
    ..This design uses compression to hold and seal the quartz flow chamber without applying torque. The system produces detection limits (3sigma) of 115 yoctomoles (70 copies) for FQ-labeled carbonic anhydrase...
  87. ncbi A capillary electrophoretic method for monitoring the presence of alpha-tubulin in nuclear preparations
    Nilhan Gunasekera
    Department of Chemistry, University of Minnesota, 207 Pleasant St SE, Minneapolis, MN 55455, USA
    Anal Biochem 330:1-9. 2004
    ....
  88. ncbi Instrumentation for medium-throughput two-dimensional capillary electrophoresis with laser-induced fluorescence detection
    Cuiru Zhu
    Department of Chemistry, University of Washington, Seattle, Washington 98195 1700, USA
    Anal Chem 79:765-8. 2007
    ..3 +/- 0.7 transfers in the CSE dimension and 0.46 +/- 0.25 s in the MECC dimension. The standard deviation in spot position was 1.8 +/- 1.2 transfers in the CSE dimension and 0.88 +/- 0.55 s in the MECC dimension. Spot capacity was 300...
  89. ncbi Evaluation of several techniques for the detection of secondary caries adjacent to amalgam restorations
    M Ando
    Department of Preventive and Community Dentistry, Oral Health Research Institute, Indiana University School of Dentistry, Indianapolis, IN 46202-2876, USA
    Caries Res 38:350-6. 2004
    ..Low sensitivity was found for VD. The results obtained in this study suggest that LF and QLF may improve the ability to detect early secondary caries around amalgam restorations...
  90. ncbi A closer look at diagnosis in clinical dental practice: part 5. Emerging technologies for caries detection and diagnosis
    Iain A Pretty
    Unit of Prosthodontics, Department of Restorative Dentistry, University Dental Hospital of Manchester, Manchester, England
    J Can Dent Assoc 70:540, 540a-540i. 2004
    ..Each technique is illustrated, the research on its effectiveness is assessed to determine usefulness to the practitioner, and the comparative advantages of the 3 adjunct tools are discussed...
  91. ncbi Caries detection and diagnosis: novel technologies
    Iain A Pretty
    Dental Health Unit, 3A Skelton House, Lloyd Street North, Manchester Science Park, Manchester, UK
    J Dent 34:727-39. 2006
    ....
  92. ncbi Tip-sample distance control using photothermal actuation of a small cantilever for high-speed atomic force microscopy
    Hayato Yamashita
    Department of Physics, Kanazawa University, Kakuma machi, Kanazawa, Japan
    Rev Sci Instrum 78:083702. 2007
    ..Using this control together with other devices optimized for high-speed scanning, video-rate imaging of protein molecules in liquids is achieved...
  93. ncbi Optical extinction monitor using cw cavity enhanced detection
    Paul L Kebabian
    Center for Sensor Systems and Technology, Aerodyne Research, Inc, 45 Manning Road, Billerica, MA 01821 3976, USA
    Rev Sci Instrum 78:063102. 2007
    ..04 Mm(-1) (4 x 10(-10) cm(-1)) (2sigma) in 10 s integration time and a base line drift of less than +/-0.1 Mm(-1) over a 24 h period. Detection limits decrease as the square root of integration time out to approximately 150 s...
  94. ncbi Toward instrument-independent quantitative measurement of fluorescence intensity in fiber-optic spectrometer systems
    Jianhua Zhao
    Laboratory for Advanced Medical Photonics, Department of Cancer Imaging, British Columbia Cancer Research Centre, University of British Columbia and Vancouver Coastal Health Research Institute, Vancouver, British Columbia V5Z 1L3, Canada
    Appl Opt 46:7132-40. 2007
    ..Experimental results showed very good agreement with theory after system-independent fluorescence intensity calibration...
  95. ncbi Photobleaching in two-photon scanning fluorescence correlation spectroscopy
    Zdeněk Petrášek
    Biophysics Group, Biotechnologisches Zentrum, Technische Universitat Dresden, Tatzberg 47 51, 01307 Dresden, Germany
    Chemphyschem 9:147-58. 2008
    ....
  96. ncbi Array based capillary IEF with a whole column image of laser-induced fluorescence in coupling to capillary RPLC as a comprehensive 2-D separation system for proteome analysis
    Yu Mao
    Department of Chemistry and Research Center for Proteome, Fudan University, Shanghai, PR China
    Proteomics 6:420-6. 2006
    ..The reproducibility of consecutive runs and different columns were assessed as having an RSD of 1.5% and 2.2% in focusing positions, respectively...
  97. ncbi Optoacoustic real-time dosimetry for selective retina treatment
    Georg Schuele
    Medical Laser Center, Lubeck, Germany
    J Biomed Opt 10:064022. 2005
    ..It detects the ophthalmoscopically invisible laser-induced damage of RPE cells and overcomes practical limitations of SRT for use in private practice...
  98. ncbi Fast photoacoustic imaging system based on 320-element linear transducer array
    Bangzheng Yin
    Institute of Laser Life Science, South China Normal University, Guangzhou 510631, People's Republic of China
    Phys Med Biol 49:1339-46. 2004
    ..The methodology and equipment thus provide a rapid and reliable approach to PA imaging that may have potential applications in noninvasive imaging and clinic diagnosis...
  99. ncbi Terahertz near-field imaging
    John F Federici
    Department of Physics, New Jersey Institute of Technology, Newark, NJ 07102, USA
    Phys Med Biol 47:3727-34. 2002
    ..5 THz. We present a study of the performance of the near-field probes in the collection mode configuration and discuss some image properties...
  100. ncbi Numerical study of wavelength-swept semiconductor ring lasers: the role of refractive-index nonlinearities in semiconductor optical amplifiers and implications for biomedical imaging applications
    A Bilenca
    Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Opt Lett 31:760-2. 2006
    ..have demonstrated unprecedented wavelength-tuning speed and repetition rate performance of semiconductor ring lasers incorporating scanning filters...
  101. ncbi Middle infrared, quantum cascade laser optoelectronic absorption system for monitoring glucose in serum
    W Blake Martin
    University of Alabama at Birmingham, Department of Biomedical Engineering, 1075 13th St S, Suite 370, AL 35294, USA
    Appl Spectrosc 59:881-4. 2005
    ..The average predictive standard errors of the mean (SEM) were 32.5 and 24.7 mg/dL, respectively, for each method. Quantum cascade lasers could be used to develop middle infrared devices for uses beyond the confines of the laboratory.

Research Grants75

  1. Short Wavelength UV Sources for Treatment of Psoriasis
    JOSEPH SMART; Fiscal Year: 2006
    ..are primarily broadband high pressure mercury lamps, mercury xenon, mercury argon and deuterium sources or excimer lasers. In practice, this has meant that phototherapy treatment methods have had to be adapted to the available light ..
  2. Port wine stain treatment for infants and young children
    Guillermo Aguilar; Fiscal Year: 2006
    ..The proposed studies investigate the appropriate use of yellow light emitted by pulsed dye lasers in combination with short cryogen spurts to improve the therapeutic outcome of port wine stains (PWS) in infants ..
  3. FACSVantage SE Upgrade
    RAYMOND HESTER; Fiscal Year: 2004
    ..FACSVantage SE flow cytometer to include DiVa electronics, TurboSort, and the replacement of fifteen-year old lasers. The projects included in this application are being conducted with faculty in five departments within the ..
  4. Structure and Biomechanics of the Human Optic Nerve Head
    Donald J Brown; Fiscal Year: 2010
    ..take advantage of known non-linear optical affects that occur when high intensity photons generated by ultrafast lasers interact with tissue...
  5. Dynamic Evaluation of Coronary Intervention
    Kevin Kip; Fiscal Year: 2006
    ..directional and rotational coronary atherectomy-to bare-metal stents-to new interventional devices including lasers and therapeutic ultrasound-to intracoronary radiation-to distal protection devices-and most recently to the widely ..
  6. ULTRAVIOLET LIGHT INDUCED PHENOMENA IN BIOMEMBRANES
    IRENE KOCHEVAR; Fiscal Year: 1999
    ..Singlet oxygen will be produced using low intensity light; radicals will be produced using pulsed lasers. The ability of mathematical modeling to predict optimal laser intensity and wavelength for photosensitization of ..
  7. Oxide Glass Fiber Optimized for Short Pulse IR Lasers
    Danh Tran; Fiscal Year: 2006
    ..79 mu/m) and Er:YAG (2.94 mu/m) lasers for therapeutic procedures...
  8. Laser Ablation of Dental Hard Tissues
    Daniel Fried; Fiscal Year: 2006
    ..In addition to eliminating the noise and vibration associated with the Dental drill, lasers offer several unique advantages over current surgical technology for conservative Dentistry...
  9. 2007 Electron Distribution & Chemical Bonding Gordon Research Conference
    Carlo Gatti; Fiscal Year: 2007
    ..TR) spectroscopy and crystallographic studies and, especially, in 5-10 years, of the X-ray Free Electron Lasers (XFEL) international facilities, the scenario of structural biology is going to amazingly change...
  10. Optical probes for controlling cellular function
    Graham Ellis Davies; Fiscal Year: 2010
    ..v.-absorbing chromophores. Uncaging using such lasers is produced by the simultaneous absorption of two red photons of equivalent energy to one blue photon...
  11. BIOPHYSICAL STUDIES OF MEMBRANE MOLECULAR DYNAMICS
    David Thomas; Fiscal Year: 1993
    ..1b) Time-resolved optical spectroscopy, using pulsed lasers, will received increased emphasis...
  12. CORE--IMAGING
    Keigi Fujiwara; Fiscal Year: 2007
    ..houses one Olympus laser scanning confocal microscope (Fluoview FV300) equipped with Krypton, Argon and He/Ne lasers for confocal microscopy and Mercury and Halogen lamps for epifluorescence and DIC/phase contrast/bright field ..
  13. Advanced Intravital Microscope
    Urs Utzinger; Fiscal Year: 2007
    ..features available in advanced microscopy systems have resulted from the development of rapidly tunable excitation lasers, sophisticated multi-channel detection systems and advanced photon counting electronics allowing time correlated ..
  14. LASER EFFECTS ON DENTAL HARD TISSUES
    John Featherstone; Fiscal Year: 2007
    ..with dental hard tissues (enamel and dentin) and to establish a scientific basis for the safe and effective use of lasers on these tissues...
  15. ULTRAFAST MULTIPHOTON LASER ACTIVATION SYSTEM
    WATT WEBB; Fiscal Year: 2001
    ..Ultrafast (approximately 100 femtosecond) pulses generated by mode-locked lasers allow simultaneous absorption of two or more photons from bright pulsed illumination for molecular excitation as ..
  16. COMPACT LASER INSTRUMENTS FOR OTOLOGIC SURGERY
    JEFFREY PIERCE; Fiscal Year: 2007
    ..7 micron ErZBLAN fiber lasers. The Phase I program has demonstrated feasibility for the 2...
  17. LASER SCANNING CONFOCAL MICROSCOPE
    Robert Lechleider; Fiscal Year: 2003
    ..The three lasers requested, argon, red Helium-Neon and green Helium-Neon, will provide excitatory signals for most applications, ..
  18. Acquisition of FACSVantage SE Flow Cytometer
    Yair Gazitt; Fiscal Year: 2004
    ..The base of the lab is a 20 year old FACSstar Plus and a 2 year old FACSCalibur analyzer equipped with 2 lasers. The FACStarPlus is equipped with a 70-CR599-dye laser with far-red excitation and an Argon laser with a standard ..
  19. Mid-Career Investigator in Patient-Oriented Research
    John Nelson; Fiscal Year: 2007
    ..D., Ph.D. training, academic affiliation, and involvement in the basic science and clinical applications of lasers make him uniquely qualified and experienced to pursue a career in patient oriented research...
  20. ZEISS LSM 510 CONFOCAL MICROSCOPE SYSTEM
    Richard Kurten; Fiscal Year: 2005
    ..We believe that the Zeiss LSM 510 with multiple lasers (405 nm to 633 nm) offers the best-integrated system available...
  21. Upgrade of Femtosecond Laser Sources for Optical Workstation
    KEVIN ELICEIRI; Fiscal Year: 2007
    ..Two femtosecond laser sources are requested. Both sources will replace/upgrade existing lasers: an older Ti:Sapphire laser and a now defunct 1047 laser...
  22. Novel Cancer Nanotechnology Platforms for Photodynamic Therapy and Imaging
    Ravindra Pandey; Fiscal Year: 2009
    ..development partnership is led by Roswell Park Cancer Institute, with the collaboration of the Institute for Lasers, Photonics and Biophotonics at the University of Buffalo, and the Department of Chemistry at the University of ..
  23. Novel Cancer Nanotechnology Platforms for Photodynamic Therapy and Imaging
    Allan Oseroff; Fiscal Year: 2007
    ..development partnership is led by Roswell Park Cancer Institute, with the collaboration of the Institute for Lasers, Photonics and Biophotonics at the University of Buffalo, and the Department of Chemistry at the University of ..