implanted electrodes

Summary

Summary: Electric conductors through which an electric current enters or leaves a medium. When inserted, usually surgically, they are referred to as implanted electrodes.

Top Publications

  1. ncbi Thalamic stimulation and functional magnetic resonance imaging: localization of cortical and subcortical activation with implanted electrodes. Technical note
    A R Rezai
    Department of Neurosurgery, New York University Medical Center, New York 10016, USA
    J Neurosurg 90:583-90. 1999
  2. ncbi Slow oscillatory activity and levodopa-induced dyskinesias in Parkinson's disease
    F Alonso-Frech
    Department of Neurology and Neurosurgery, Neuroscience Area, Clinica Universitaria and Centro de Investigación Médica Aplicada CIMA, Universidad de Navarra Pamplona, Spain
    Brain 129:1748-57. 2006
  3. ncbi MEP latency shift after implantation of deep brain stimulation systems in the subthalamic nucleus in patients with advanced Parkinson's disease
    Ute Hidding
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Germany
    Mov Disord 21:1471-6. 2006
  4. ncbi Can pacemakers, neurostimulators, leads, or guide wires be MRI safe? Technological concerns and possible resolutions
    Jeffrey L Helfer
    Biophan Technologies, Inc, Rochester, New York 14586, USA
    Minim Invasive Ther Allied Technol 15:114-20. 2006
  5. ncbi Hypomania as an adverse effect of subthalamic nucleus stimulation: report of two cases
    T S Mandat
    Division of Neurosurgery, University of British Columbia, Vancouver, Canada
    Acta Neurochir (Wien) 148:895-7; discussion 898. 2006
  6. ncbi Deep brain stimulation for Parkinson's disease dissociates mood and motor circuits: a functional MRI case study
    Taresa Stefurak
    Rotman Research Institute, University of Toronto, Toronto, Ontario, Canada
    Mov Disord 18:1508-16. 2003
  7. ncbi High-frequency oscillations during human focal seizures
    J D Jirsch
    Montreal Neurological Institute and Hospital, Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada
    Brain 129:1593-608. 2006
  8. ncbi Frequency dependent effects of subthalamic nucleus stimulation in Parkinson's disease
    Noa Fogelson
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WCIN 3BG, UK
    Neurosci Lett 382:5-9. 2005
  9. ncbi Patterning of globus pallidus local field potentials differs between Parkinson's disease and dystonia
    Paul Silberstein
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WCIN 3BG, UK
    Brain 126:2597-608. 2003
  10. ncbi Interictal high-frequency oscillations (100-500 Hz) in the intracerebral EEG of epileptic patients
    Elena Urrestarazu
    Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada
    Brain 130:2354-66. 2007

Research Grants

Detail Information

Publications210 found, 100 shown here

  1. ncbi Thalamic stimulation and functional magnetic resonance imaging: localization of cortical and subcortical activation with implanted electrodes. Technical note
    A R Rezai
    Department of Neurosurgery, New York University Medical Center, New York 10016, USA
    J Neurosurg 90:583-90. 1999
    ..This approach offers great potential for understanding the mechanisms of action of deep brain stimulation and those underlying pain and tremor generation...
  2. ncbi Slow oscillatory activity and levodopa-induced dyskinesias in Parkinson's disease
    F Alonso-Frech
    Department of Neurology and Neurosurgery, Neuroscience Area, Clinica Universitaria and Centro de Investigación Médica Aplicada CIMA, Universidad de Navarra Pamplona, Spain
    Brain 129:1748-57. 2006
    ..When dyskinesias were only present in one limb (n = 2), the 4-10 Hz peak was only recorded in the contralateral STN. These findings suggest that the 4-10 Hz oscillation is associated with the expression of LID in Parkinson's disease...
  3. ncbi MEP latency shift after implantation of deep brain stimulation systems in the subthalamic nucleus in patients with advanced Parkinson's disease
    Ute Hidding
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Germany
    Mov Disord 21:1471-6. 2006
    ..These TMS effects need to be considered when interpreting results of excitability measurements in PD patients after implantation of STN electrodes...
  4. ncbi Can pacemakers, neurostimulators, leads, or guide wires be MRI safe? Technological concerns and possible resolutions
    Jeffrey L Helfer
    Biophan Technologies, Inc, Rochester, New York 14586, USA
    Minim Invasive Ther Allied Technol 15:114-20. 2006
    ..As the problem is very complex and the variety of implants is large, this paper focuses on the problems of MRI-induced lead heating...
  5. ncbi Hypomania as an adverse effect of subthalamic nucleus stimulation: report of two cases
    T S Mandat
    Division of Neurosurgery, University of British Columbia, Vancouver, Canada
    Acta Neurochir (Wien) 148:895-7; discussion 898. 2006
    ..Readjusting the stimulation parameters resolved the hypomania with continued motor benefits. The authors draw attention to potential adverse effects of STN-DBS that might be neglected by patients...
  6. ncbi Deep brain stimulation for Parkinson's disease dissociates mood and motor circuits: a functional MRI case study
    Taresa Stefurak
    Rotman Research Institute, University of Toronto, Toronto, Ontario, Canada
    Mov Disord 18:1508-16. 2003
    ....
  7. ncbi High-frequency oscillations during human focal seizures
    J D Jirsch
    Montreal Neurological Institute and Hospital, Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada
    Brain 129:1593-608. 2006
    ..Our finding that localized HFOs occur in varying anatomical structures and pathological conditions perhaps indicates commonality to diverse epileptogenic aetiologies...
  8. ncbi Frequency dependent effects of subthalamic nucleus stimulation in Parkinson's disease
    Noa Fogelson
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WCIN 3BG, UK
    Neurosci Lett 382:5-9. 2005
    ..This is consistent with the hypothesis that spontaneous activities in these bands might promote bradykinesia...
  9. ncbi Patterning of globus pallidus local field potentials differs between Parkinson's disease and dystonia
    Paul Silberstein
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WCIN 3BG, UK
    Brain 126:2597-608. 2003
    ..We conclude that untreated and treated Parkinson's disease and dystonia are characterized by different spatiotemporal patterns of activity in the human pallidum...
  10. ncbi Interictal high-frequency oscillations (100-500 Hz) in the intracerebral EEG of epileptic patients
    Elena Urrestarazu
    Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada
    Brain 130:2354-66. 2007
    ..Our results also suggest a special capacity of the abnormal hippocampus to generate FRs, although they were also recorded in other structures...
  11. ncbi Ten-Hertz stimulation of subthalamic nucleus deteriorates motor symptoms in Parkinson's disease
    Lars Timmermann
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Mov Disord 19:1328-33. 2004
    ..This finding indicates the clinical relevance of pathological 10 Hz synchronization in PD...
  12. pmc Techniques for extracting single-trial activity patterns from large-scale neural recordings
    Mark M Churchland
    Neurosciences Program and Department of Electrical Engineering, Stanford University, CISX, 330 Serra Mall, Stanford, CA 94305 4075, United States
    Curr Opin Neurobiol 17:609-18. 2007
    ....
  13. ncbi Occipital nerve stimulation for drug-resistant chronic cluster headache: a prospective pilot study
    Delphine Magis
    Headache Research Unit, Department of Neurology, Liege University, CHR Citadelle, Liege, Belgium
    Lancet Neurol 6:314-21. 2007
    ..Occipital nerve stimulation (ONS) is a new, safe strategy for intractable headaches. We undertook a prospective pilot trial of ONS in drCCH to assess clinical efficacy and pain perception...
  14. doi Replay of rule-learning related neural patterns in the prefrontal cortex during sleep
    Adrien Peyrache
    College de France, Centre National de la Recherche Scientifique, Paris, France
    Nat Neurosci 12:919-26. 2009
    ..Therefore, learning, or the resulting reliable reward, influenced which patterns were most strongly encoded and successively reactivated in the hippocampal/prefrontal network...
  15. ncbi Computer control using human intracortical local field potentials
    Philip R Kennedy
    Neural Signals, Inc, Atlanta, GA 30340, USA
    IEEE Trans Neural Syst Rehabil Eng 12:339-44. 2004
    ..This report focuses on the progress of two subjects toward effective use of their "virtual" neuro-prosthetic devices to meet their assistive technology needs...
  16. ncbi Transient mania with hypersexuality after surgery for high frequency stimulation of the subthalamic nucleus in Parkinson's disease
    Luigi Michele Romito
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italy
    Mov Disord 17:1371-4. 2002
    ..We describe 2 men who developed mania and hypersexuality a few days after the implant that lasted for some months and then gradually disappeared spontaneously...
  17. ncbi Beta oscillatory activity in the subthalamic nucleus and its relation to dopaminergic response in Parkinson's disease
    Moran Weinberger
    Department of Physiology, Med Sci Building 3302, 1 King s College Circle, University of Toronto, Toronto, Ontario M5S 1A8, Canada
    J Neurophysiol 96:3248-56. 2006
    ..The study also suggests that LFP beta oscillatory activity is generated largely within the dorsal portion of the STN and can produce synchronous oscillatory activity of the local neuronal population...
  18. ncbi Dopamine-dependent changes in the functional connectivity between basal ganglia and cerebral cortex in humans
    David Williams
    Sobell Department of Neurophysiology, Institute of Neurology, London, UK
    Brain 125:1558-69. 2002
    ....
  19. doi Spinomuscular coherence in monkeys performing a precision grip task
    Tomohiko Takei
    Department of Developmental Physiology, National Institute for Physiological Sciences, 38 Nishigounaka, Myodaiji, Okazaki, Aichi 444 8585, Japan
    J Neurophysiol 99:2012-20. 2008
    ..On the other hand, the broadband coherence could be a unique feature of spinal motoneuron-muscle physiology...
  20. ncbi Dopamine dependency of oscillations between subthalamic nucleus and pallidum in Parkinson's disease
    P Brown
    Medical Research Council Human Movement and Balance Unit, Institute of Neurology, London WCIN 3BG, United Kingdom
    J Neurosci 21:1033-8. 2001
    ..Synchronization of activity does occur between pallidum and STN, and its pattern is critically dependent on the level of dopaminergic activity...
  21. ncbi Effects of stimulation of the subthalamic area on oscillatory pallidal activity in Parkinson's disease
    Peter Brown
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London WCIN 3BG, UK
    Exp Neurol 188:480-90. 2004
    ..If this activity is unchecked by synchronisation at higher frequency, then pathological 20-Hz oscillations may cascade through the basal ganglia, increasing at subsequent levels of processing...
  22. ncbi EEG-based neuroprosthesis control: a step towards clinical practice
    Gernot R Müller-Putz
    Institute for Computer Graphics and Vision, Laboratory of Brain Computer Interfaces, Graz University of Technology, Inffeldgasse 16a, 8010 Graz, Austria
    Neurosci Lett 382:169-74. 2005
    ..The fact that the user learned to control the BCI in a comparatively short time indicates that this method may also be an alternative approach for clinical purposes...
  23. ncbi Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats
    Hanneke K M Meeren
    Department of Comparative and Physiological Psychology, Nijmegen Institute of Cognition and Information, University of Nijmegen, 6500 HE Nijmegen, The Netherlands
    J Neurosci 22:1480-95. 2002
    ..Analogous mechanisms may underlie the pathophysiology of human absence epilepsy...
  24. ncbi Intra-operative recordings of local field potentials can help localize the subthalamic nucleus in Parkinson's disease surgery
    Chiung Chu Chen
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WCIN 3BG, UK
    Exp Neurol 198:214-21. 2006
    ..Functional physiological localization of STN by the on-line spectral analysis of LFPs is quick to perform and may provide information directly relevant to the position of the electrode contact actually used for DBS...
  25. ncbi Analysis of chronic seizure onsets after intrahippocampal kainic acid injection in freely moving rats
    Anatol Bragin
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Epilepsia 46:1592-8. 2005
    ..The goal of this study was to analyze the transition period between interictal and ictal activity in freely moving rats with recurrent spontaneous seizures after unilateral intrahippocampal kainic acid (KA) injection...
  26. ncbi Functional MRI with active, fully implanted, deep brain stimulation systems: safety and experimental confounds
    David W Carmichael
    Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK
    Neuroimage 37:508-17. 2007
    ..Further studies are required to determine the safety of MRI with DBS for other MRI systems, transmit coil configurations and DBS arrangements...
  27. ncbi Functional organization of ferret auditory cortex
    Jennifer K Bizley
    University Laboratory of Physiology, Parks Road, Oxford OX1 3PT, UK
    Cereb Cortex 15:1637-53. 2005
    ..The presence of both tonotopic and non-tonotopic auditory cortical fields indicates that the organization of ferret auditory cortex is comparable to that seen in other mammals...
  28. ncbi The relationship between local field potential and neuronal discharge in the subthalamic nucleus of patients with Parkinson's disease
    Andrea A Kuhn
    Department of Neurology, Charite Campus Virchow, Humboldt University, Berlin, Germany
    Exp Neurol 194:212-20. 2005
    ..The LFP is therefore likely to represent synchronous activity in populations of neurons in the STN of patients with PD...
  29. ncbi Recording chronically from the same neurons in awake, behaving primates
    Andreas S Tolias
    Max Planck Institute for Biological Cybernetics, Tubingen, Germany
    J Neurophysiol 98:3780-90. 2007
    ..The chronic recording techniques and methods of analyses we report can be used to characterize the changes in brain circuits due to learning...
  30. ncbi Stimulation of the subthalamic nucleus changes the firing pattern of pallidal neurons
    Takao Hashimoto
    Department of Neurology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Neurosci 23:1916-23. 2003
    ....
  31. ncbi Intracranial EEG substrates of scalp EEG interictal spikes
    James X Tao
    Department of Neurology, Adult Epilepsy Center, University of Chicago, Illinois 60637, USA
    Epilepsia 46:669-76. 2005
    ..To determine the area of cortical generators of scalp EEG interictal spikes, such as those in the temporal lobe epilepsy...
  32. ncbi Connectivity of an effective hypothalamic surgical target for cluster headache
    S L F Owen
    University Laboratory of Physiology, University of Oxford, Oxford, UK
    J Clin Neurosci 14:955-60. 2007
    ..Our results illustrate important anatomical connections that may explain the functional changes associated with cluster headaches and elucidate possible mechanisms responsible for triggering attacks...
  33. ncbi Neural probe design for reduced tissue encapsulation in CNS
    John P Seymour
    Department of Biomedical Engineering, University of Michigan, 2212 Lurie Biomedical Engineering Building, 1101 Beal Avenue, Ann Arbor, MI 48109 2099, USA
    Biomaterials 28:3594-607. 2007
    ..There were no significant differences among platform designs. These results suggest that neural probe geometry is an important parameter for reducing chronic tissue encapsulation...
  34. ncbi Laminar analysis of human neocortical interictal spike generation and propagation: current source density and multiunit analysis in vivo
    Istvan Ulbert
    Department of Neurosurgery, Stanford University Medical Center, Stanford, California, USA
    Epilepsia 45:48-56. 2004
    ....
  35. doi A method for chronic stimulation of cortical organotypic cultures using implanted electrodes
    Hope A Johnson
    Departments of Neurobiology and Psychology, and Brain Research Institute, University of California, Los Angeles, Los Angeles, CA 90095, United States
    J Neurosci Methods 176:136-43. 2009
    ..This technique establishes a reduced model for studying experience-dependent plasticity...
  36. ncbi Vagus nerve stimulation in children less than 5 years old
    Jeffrey P Blount
    Section of Pediatric Neurosurgery, University of Alabama at Birmingham and Children s Hospital Birmingham, 1600 7th Avenue South ACC 400, Birmingham, AL 35233, USA
    Childs Nerv Syst 22:1167-9. 2006
    ..Vagus nerve stimulation (VNS) has been used in both adults and older children with varying success...
  37. doi Vagus nerve stimulation: current concepts
    Timothy B Mapstone
    Department of Neurological Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Neurosurg Focus 25:E9. 2008
    ..Although initially approved for adults, it increasingly has gained acceptance in children. In this article the author reviews the current state of knowledge of VNS therapy and discusses its potential utility...
  38. ncbi Local sensory cues and place cell directionality: additional evidence of prospective coding in the hippocampus
    Francesco P Battaglia
    Arizona Research Laboratories, Division of Neural Systems, Memory, and Aging, University of Arizona, Tucson, Arizona 85724 5115, USA
    J Neurosci 24:4541-50. 2004
    ....
  39. ncbi Stimulation of the posterior hypothalamus for treatment of chronic intractable cluster headaches: first reported series
    Angelo Franzini
    Department of Neurosurgery, Istituto Nazionale Neurologico C Besta, Milan, Italy
    Neurosurgery 52:1095-9; discussion 1099-101. 2003
    ..To describe the results of deep brain stimulation of the ipsilateral posterior hypothalamus for the treatment of drug-resistant chronic cluster headaches (CHs). A technique for electrode placement is reported...
  40. ncbi In vivo laminar electrophysiology co-registered with histology in the hippocampus of patients with temporal lobe epilepsy
    Istvan Ulbert
    Institute of Experimental Medicine of the Hungarian Academy of Sciences, Budapest 1450, Hungary
    Exp Neurol 187:310-8. 2004
    ..Electrophysiological identification of the functional state of the hippocampus together with its local structural correlates could further enhance our understanding of this disease...
  41. ncbi Cortical stimulation for parkinsonism
    Sergio Canavero
    Arch Neurol 61:606. 2004
  42. ncbi Evidence from retractor bulbi EMG for linearized motor control of conditioned nictitating membrane responses
    N F Lepora
    Department of Psychology, University of Sheffield, Sheffield, UK
    J Neurophysiol 98:2074-88. 2007
    ..To study this question, the retractor bulbi muscle EMG was recorded with implanted electrodes during NM conditioning...
  43. pmc High-frequency oscillations in human temporal lobe: simultaneous microwire and clinical macroelectrode recordings
    Greg A Worrell
    Department of Neurology, Mayo Clinic, 200 First St SW, Rochester, MN 55901, USA
    Brain 131:928-37. 2008
    ..Future research will address the clinical utility of these recordings for localizing epileptogenic networks and understanding seizure generation...
  44. doi Large, single-center, single-operator experience with transvenous lead extraction: outcomes and changing indications
    Samuel O Jones
    Arrhythmia Service, Department of Cardiovascular Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Heart Rhythm 5:520-5. 2008
    ..Lead extraction is increasingly necessary given the exponential growth in cardiac device implantation. Meanwhile, the tools, indications, and outcomes of this procedure continue to change...
  45. ncbi Laser-assisted lead extraction: the European experience
    C Kennergren
    Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, S 413 45 Gothenburg, Sweden
    Europace 9:651-6. 2007
    ..The aim of this study is to investigate the safety and effectiveness of Excimer laser-assisted lead extraction in Europe. The final European multi-centre study experience is presented...
  46. ncbi Spike synchronization in the cortex/basal-ganglia networks of Parkinsonian primates reflects global dynamics of the local field potentials
    Joshua A Goldberg
    Department of Physiology, Hadassah Medical School, The Hebrew University, Jerusalem 91120, Israel
    J Neurosci 24:6003-10. 2004
    ..We propose that, in the parkinsonian condition, the cortex-basal ganglia networks are more tightly related to global modes of brain dynamics that are echoed in the LFP...
  47. ncbi Extradural motor cortex stimulation in advanced Parkinson's disease: the Turin experience: technical case report
    Carlo Alberto Pagni
    Neurosurgical Clinic, University of Turin, Turin, Italy
    Neurosurgery 57:E402; discussion E402. 2005
    ..At our institution, extradural motor cortex stimulation (EMCS) has recently been applied for treating Parkinson's disease symptoms. We report our results and review the literature supporting this application of EMCS...
  48. pmc Response properties of neighboring neurons in the auditory midbrain for pure-tone stimulation: a tetrode study
    Chandran V Seshagiri
    Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    J Neurophysiol 98:2058-73. 2007
    ..Because the CP is related to the neural mechanisms generating the ITD sensitivity, this result is consistent with segregation of inputs to the ICC from the lateral and medial superior olives...
  49. ncbi Magnetic-resonance-induced heating of implantable leads
    Michele Triventi
    Dipartimento di Tecnologie e Salute, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Ann Ist Super Sanita 43:229-40. 2007
    ..Experiments reveled that the implant location and configuration are crucial elements for the heat generation at the lead tip...
  50. ncbi Voltage depth profiles of high-frequency oscillations after kainic acid-induced status epilepticus
    Anatol Bragin
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Epilepsia 48:35-40. 2007
    ..In areas outside of the generator of the BPS, this activity looks more like pathological high-frequency oscillations (pHFO), which were observed in earlier experiments...
  51. ncbi Evaluation of specific absorption rate as a dosimeter of MRI-related implant heating
    Kenneth B Baker
    Department of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk S 90, Cleveland, OH 44195, USA
    J Magn Reson Imaging 20:315-20. 2004
    ..To compare the magnetic resonance imaging (MRI)-related heating per unit of whole body averaged specific absorption rate (SAR) of a conductive implant exposed to two different 1.5-Tesla/64 MHz MR systems...
  52. ncbi Left ventricular lead placement within a coronary sinus side branch using remote magnetic navigation of a guidewire: a feasibility study
    Maximo Rivero-Ayerza
    Department of Clinical Electrophysiology, Thoraxcenter Erasmus MC, Rotterdam, The Netherlands
    J Cardiovasc Electrophysiol 17:128-33. 2006
    ..A novel magnetic navigation system (MNS) allowing remote guidance of catheters and guidewires might assist in implantation of left ventricular (LV) pacing leads...
  53. ncbi Reliability of signals from a chronically implanted, silicon-based electrode array in non-human primate primary motor cortex
    Selim Suner
    Department of Emergency Medicine and Surgery, Brown University, Providence, RI 02912, USA
    IEEE Trans Neural Syst Rehabil Eng 13:524-41. 2005
    ....
  54. ncbi Cognitive control signals for neural prosthetics
    S Musallam
    Division of Biology, California Institute of Technology, Mail code 216 76, Pasadena, CA 91125, USA
    Science 305:258-62. 2004
    ..For neural prosthetic applications, the goal signals can be used to operate computers, robots, and vehicles, whereas the expected value signals can be used to continuously monitor a paralyzed patient's preferences and motivation...
  55. doi Lead extraction: a new effective tool to overcome fibrous binding sites
    Antonio Dello Russo
    Cardiac Arrhythmia and Heart Failure Research Center, Catholic University of Sacred Heart St Camillo Forlanini Hospital, Rome, Italy
    J Interv Card Electrophysiol 24:147-50. 2009
    ....
  56. ncbi The human spiral ganglion: new insights into ultrastructure, survival rate and implications for cochlear implants
    Rudolf Glueckert
    Department of Otolaryngology, Institute of Anatomy and Histology, Medical University of Innsbruck, Innsbruck, Austria
    Audiol Neurootol 10:258-73. 2005
    ..Moreover, the fragile bony columns connecting the spiral canal with the osseous spiral lamina may be a potential site for trauma in (perimodiolar) electrode positioning...
  57. ncbi Influence of bilateral Stn-stimulation on psychiatric symptoms and psychosocial functioning in patients with Parkinson's disease
    K Kalteis
    Department of Neurosurgery, Medical University of Vienna, Vienna, Austria
    J Neural Transm 113:1191-206. 2006
    ..The results suggest that stimulation of the subthalamic nucleus has a positive influence on psychiatric symptoms, psychosocial functioning and distress. We observed a decline in a minority of patients...
  58. ncbi Neuropsychological functioning following bilateral subthalamic nucleus stimulation in Parkinson's disease
    C E Morrison
    New York University Medical Center, New York, NY, USA
    Arch Clin Neuropsychol 19:165-81. 2004
    ..There were no surgery, stimulation, or procedure effects on depression scale scores. In contrast to these group findings, one DBS patient demonstrated significant cognitive decline following surgery...
  59. ncbi Active deep brain stimulation during MRI: a feasibility study
    J C Georgi
    Division of Neuroradiology, Department of Neurology, University of Heidelberg Medical Center, Heidelberg, Germany
    Magn Reson Med 51:380-8. 2004
    ..However, it was demonstrated that under certain conditions, safe MR examinations during active DBS are feasible. Certain safety precautions are recommended in this report...
  60. ncbi Dopaminergic therapy promotes lateralized motor activity in the subthalamic area in Parkinson's disease
    Alexandros G Androulidakis
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK
    Brain 130:457-68. 2007
    ..These findings suggest that dopaminergic therapy restores a more physiological pattern of reactivity in the STN of patients with Parkinson's disease...
  61. pmc An implanted upper-extremity neuroprosthesis using myoelectric control
    Kevin L Kilgore
    MetroHealth Medical Center, Cleveland, OH, USA
    J Hand Surg Am 33:539-50. 2008
    ..The key feature of this system is that users control their stimulated function through electromyographic (EMG) signals...
  62. ncbi Clinical study of the laser sheath for lead extraction: the total experience in the United States
    Charles L Byrd
    Broward General Medical Center, Fort Lauderdale, Florida, USA
    Pacing Clin Electrophysiol 25:804-8. 2002
    ..Success is independent of laser sheath size. Major complications can be expected in < 2% of patients, and occur more often during an investigator's early experience...
  63. ncbi Mania following deep brain stimulation for Parkinson's disease
    J Kulisevsky
    Movement Disorders Unit, Department of Neurology, Functional Neurosurgery Program for Movement Disorders, Sant Pau Hospital, Autonomous University of Barcelona, Spain
    Neurology 59:1421-4. 2002
    ....
  64. ncbi The oscillatory activity in the Parkinsonian subthalamic nucleus investigated using the macro-electrodes for deep brain stimulation
    X Liu
    University Laboratory of Physiology, University of Oxford, Parks Road, Oxford OX1 3PT, UK
    Clin Neurophysiol 113:1667-72. 2002
    ..To investigate the oscillatory activity in the Parkinsonian subthalamic nucleus using the macro-electrodes for deep brain stimulation...
  65. ncbi Quantitative analysis of high-frequency oscillations (80-500 Hz) recorded in human epileptic hippocampus and entorhinal cortex
    Richard J Staba
    Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    J Neurophysiol 88:1743-52. 2002
    ..The strong association between FR and regions of seizure initiation supports the view that FR reflects pathological hypersynchronous events crucially associated with seizure genesis...
  66. ncbi Laser lead extraction: predictors of success and complications
    Jean Francois Roux
    Electrophysiology Service, Department of Cardiology, Montreal Heart Institute, Montreal, Canada
    Pacing Clin Electrophysiol 30:214-20. 2007
    ..Paralleling the rise in pacemaker and defibrillator implantations, lead extraction procedures are increasingly required. Concerns regarding failure and complications remain...
  67. ncbi Pacemaker and ICD lead extraction with electrosurgical dissection sheaths and standard transvenous extraction systems: results of a randomized trial
    Petr Neuzil
    Cardiology Department, Na Homolce Hospital, Roentgenova 2, Prague 515030, Czech Republic
    Europace 9:98-104. 2007
    ..Serious bleeding occurred in three patients, one with standard and two with the EDS lead extraction system...
  68. ncbi Effect of deep insertion of the cochlear implant electrode array on pitch estimation and speech perception
    Jafar Hamzavi
    Department of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria
    Acta Otolaryngol 126:1182-7. 2006
    ..Deeply inserted electrodes offer the possibility that apical stimulation may improve speech performances. Therefore, deep insertion is reasonable and should be performed in patients with profound or total hearing loss...
  69. ncbi Neuroprostheses for grasping
    Milos R Popovic
    Institute of Biomaterials and Biomedical Engineering, University of Toronto, Canada
    Neurol Res 24:443-52. 2002
    ..This article also provides a brief summary of the achieved results with the existing neuroprostheses for grasping and discusses some of the challenges this technology is currently facing...
  70. ncbi A grateful heart
    Maximo Rivero-Ayerza
    Thorax Center, Erasmus MC, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Europace 9:533. 2007
  71. ncbi Determination of left ventricular volume changes by intracardiac conductance using a biventricular electrode configuration
    Endre Zima
    Department of Cardiovascular Surgery, Semmelweis University, Budapest, Hungary
    Europace 8:537-44. 2006
    ..The feasibility of determining left ventricular (LV) volume changes by LV conductance measurements with an implantable device was investigated in an animal model...
  72. doi Simultaneous magnetoencephalography and intracranial EEG registration: technical and clinical aspects
    Marta Santiuste
    Magnetoencephalography Unit, Centro Medico Teknon, Barcelona, Spain daggerEpilepsy Unit, Centro Medico Teknon, Barcelona, Spain
    J Clin Neurophysiol 25:331-9. 2008
    ..MEG can detect and localize interictal epileptiform spikes that are recorded from depth electrodes in both neocortical and mesial structures, despite the lesser amplitude of spikes of mesial origin...
  73. ncbi Left ventricular lead implantation assisted by magnetic navigation in a patient with a persistent left superior vena cava
    Maximo Rivero-Ayerza
    Int J Cardiol 116:e15-7. 2007
    ..Intra-cardiac echocardiography was helpful in locating the coronary sinus os...
  74. ncbi Deep electrode insertion in cochlear implants: apical morphology, electrodes and speech perception results
    Ingeborg Hochmair
    Medical Electronics, Innsbruck, Austria
    Acta Otolaryngol 123:612-7. 2003
    ....
  75. pmc Microphysiology of epileptiform activity in human neocortex
    Catherine A Schevon
    Department of Neurology, Columbia University, New York, New York, USA
    J Clin Neurophysiol 25:321-30. 2008
    ..The authors hypothesize that microdischarges and microseizures are generated by small cortical domains that form the substrate of epileptogenic cortex and play important roles in seizure initiation and propagation...
  76. ncbi Criteria for the selection of materials for implanted electrodes
    L A Geddes
    Purdue University, Department of Biomedical Engineering, 500 Central Drive, West Lafayette, IN 47907 2022, USA
    Ann Biomed Eng 31:879-90. 2003
    ..The paper concludes with an analysis, the design criteria, and the special properties and materials for capacitive recording and stimulating electrodes...
  77. doi Interictal magnetoencephalography and the irritative zone in the electrocorticogram
    Z Agirre-Arrizubieta
    Department of Neurology and Clinical Neurophysiology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    Brain 132:3060-71. 2009
    ..However, a substantial number of interictal ECoG spikes are not detected by MEG, and therefore MEG cannot be considered a substitute for ECoG...
  78. pmc Initial surgical experience with a dense cortical microarray in epileptic patients undergoing craniotomy for subdural electrode implantation
    Allen Waziri
    Department of Neurosurgery, The Neurological Institute, Columbia University, New York, New York 10032, USA
    Neurosurgery 64:540-5; discussion 545. 2009
    ..Salt Lake City, UT) in a series of patients undergoing subdural electrode implantation for epilepsy monitoring...
  79. ncbi Pseudo-bilateral hand motor responses evoked by transcranial magnetic stimulation in patients with deep brain stimulators
    A A Kühn
    Department of Neurology, Charite, Campus Virchow Klinikum, Humboldt University Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    Clin Neurophysiol 113:341-5. 2002
    ..The aim of this study was to clarify the origin of these ipsilateral responses...
  80. pmc Neuronal basis of crossed actions from the reticular formation on feline hindlimb motoneurons
    Elzbieta Jankowska
    Department of Physiology, Goteborg University, 405 30 Goteborg, Sweden
    J Neurosci 23:1867-78. 2003
    ..They indicate a close coupling between the spinal interneuronal systems used by the reticulospinal neurons to coordinate muscle contractions ipsilaterally and contralaterally...
  81. ncbi Electrode insertion depth in cochlear implantees estimated during surgery, on plain film radiographs and with electrode function testing
    Robert H R Bettman
    Department of Otorhinolaryngology, St Jansdal Hospital, Wethouder Jansenlaan 90, 3844 DG Harderwijk, The Netherlands
    Eur Arch Otorhinolaryngol 260:536-40. 2003
    ..Plain film radiography using Stenvers projection is satisfactory if imaging is indicated for determining the number of inserted electrodes...
  82. doi Intravascular lead extraction using the excimer laser: pitfalls and tips for success
    Robert W Feldtman
    Department of Surgery, Texas A and M Health Science Center College of Medicine, and Division of Vascular Surgery, Scott and White Memorial Hospital, Temple, TX 76508, USA
    Semin Vasc Surg 21:54-6. 2008
    ..This article outlines a few suggestions for avoiding severe complications with this useful procedure...
  83. doi Bioimpedance modeling to monitor astrocytic response to chronically implanted electrodes
    G C McConnell
    Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology Emory University, Atlanta, 30332, USA
    J Neural Eng 6:055005. 2009
    ..devices is currently hindered by our inability to reliably record neural signals from chronically implanted electrodes. The extent to which the local tissue response to implanted electrodes influences recording failure is not ..
  84. ncbi Chronic high-frequency deep brain stimulation of the STN/SNr for progressive myoclonic epilepsy
    Jan Vesper
    Department of Stereotactic Neurosurgery, Neurocenter, Freiburg University Hospital, Freiburg, Germany
    Epilepsia 48:1984-9. 2007
    ..A subsequent prospective study will have to investigate whether the STN or other target nuclei are most suitable for DBS in these types of epilepsy and which long-term results can be obtained...
  85. ncbi Subthalamic nucleus stimulation modulates motor cortex oscillatory activity in Parkinson's disease
    D Devos
    Department of Neurology, Lille University Medical Center, France
    Brain 127:408-19. 2004
    ....
  86. ncbi Is vagus nerve stimulation a treatment option for patients with drug-resistant idiopathic generalized epilepsy?
    H Kostov
    Department of Neurodiagnostics, National Centre for Epilepsy, Division of Clinical Neuroscience, Rikshospitalet University Hospital Oslo, Norway
    Acta Neurol Scand Suppl 187:55-8. 2007
    ..The value of vagus nerve stimulation (VNS) for treating patients with drug-resistant idiopathic generalized epilepsy (IGE) is not well documented...
  87. ncbi Human nerve stimulation thresholds and selectivity using a multi-contact nerve cuff electrode
    Katharine H Polasek
    Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA
    IEEE Trans Neural Syst Rehabil Eng 15:76-82. 2007
    ..This study serves as a preliminary evaluation of nerve cuff electrodes in humans prior to chronic implant in subjects with high tetraplegia...
  88. ncbi Anti-convulsant effect of electrical stimulation and lesioning of the anterior thalamic nucleus on kainic acid-induced focal limbic seizure in rats
    Seiji Takebayashi
    Department of Neurosurgery, Asahikawa Medical College, 2 1 Midorigaoka Higashi, Asahikawa 078 8510, Japan
    Epilepsy Res 74:163-70. 2007
    ..To address the mechanism underlying these anti-convulsant actions, cerebral glucose metabolism following ANT electrical stimulation and lesioning was also assessed...
  89. ncbi A new approach towards a minimal invasive retina implant
    H Gerding
    Department of Retinology, Klinik Pallas, Olten, Switzerland
    J Neural Eng 4:S30-7. 2007
    ..Successful data about this type of retinal prosthesis are already available from long-term observation in non-human primates...
  90. ncbi Intraspinal microstimulation using cylindrical multielectrodes
    Sean Snow
    Department of Bioengineering, University of Utah, Salt Lake City 84112, USA
    IEEE Trans Biomed Eng 53:311-9. 2006
    ..Specifications of an array of cylindrical multielectrodes for use in future intraspinal microstimulation prostheses were updated...
  91. ncbi Microfabricated cylindrical multielectrodes for neural stimulation
    Sean Snow
    Department of Bioengineering, University of Utah, Salt Lake City 84112, USA
    IEEE Trans Biomed Eng 53:320-6. 2006
    ..6 mC/cm2) and damaging levels (> or = 0.8 mC/cm2) of charge density. The results of these tests suggest that this electrode design could be used to stimulate neurons in the ventral horn of the spinal cord...
  92. ncbi The age of neuroelectronics
    Adam Keiper
    The New Atlantis, USA
    New Atlantis 11:4-41. 2006
  93. ncbi Real-time refinement of subthalamic nucleus targeting using Bayesian decision-making on the root mean square measure
    Anan Moran
    Gonda Multidisciplinary Brain Research Center and Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel
    Mov Disord 21:1425-31. 2006
    ....
  94. ncbi Neuromodulation of the centromedian thalamic nuclei in the treatment of generalized seizures and the improvement of the quality of life in patients with Lennox-Gastaut syndrome
    Ana Luisa Velasco
    Unit of Stereotactic, Functional Neurosurgery and Radiosurgery, Hospital General de Mexico, Mexico City, Mexico
    Epilepsia 47:1203-12. 2006
    ..Our aim was to evaluate the efficacy of ESCM (electrical stimulation of the centromedian thalamic nucleus) in treatment of generalized seizures of the Lennox-Gastaut syndrome (LGS) and improvement of patient disability...
  95. ncbi An optically powered single-channel stimulation implant as test system for chronic biocompatibility and biostability of miniaturized retinal vision prostheses
    Thomas Schanze
    Department of Physics, Philipps University Marburg, Renthof 7, 35037 Marburg, Germany
    IEEE Trans Biomed Eng 54:983-92. 2007
    ..In one cat, electrical stimulation of the retina evoked neuronal responses in the visual cortex and indicated the feasibility of the system approach for chronic use...
  96. ncbi Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease
    Ali Samii
    Department of Neurology, University of Washington, Seattle, Washington, USA
    Mov Disord 22:1476-81. 2007
    ..Most of the improvements in off-medication ADL scores, dyskinesia scores, complications of therapy, and medication dose reduction occurred after unilateral STN stimulation with smaller improvements after the second operation...
  97. ncbi Feasibility of extraocular stimulation for a retinal prosthesis
    Vivek Chowdhury
    Department of Ophthalmology, Prince of Wales Clinical School, University of New South Wales, Sydney, Australia
    Can J Ophthalmol 40:563-72. 2005
    ..We present a new approach to developing a retinal prosthesis for blind patients based on extraocular stimulation of the eye with disc electrodes...
  98. ncbi Chronic vestibulo-ocular reflexes evoked by a vestibular prosthesis
    Daniel M Merfeld
    Jenks Vestibular Physiology Lab, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    IEEE Trans Biomed Eng 54:1005-15. 2007
    ..This suggests that long-term functional replacement of absent vestibular function is feasible...
  99. pmc Stimulation of subterritories of the subthalamic nucleus reveals its role in the integration of the emotional and motor aspects of behavior
    Luc Mallet
    Institut National de la Santé et de la Recherche Médicale AVENIR Group, Behavior, Emotion, and Basal Ganglia, 75013 Paris, France
    Proc Natl Acad Sci U S A 104:10661-6. 2007
    ....
  100. ncbi Experience with microelectrode guided subthalamic nucleus deep brain stimulation
    Ramin Amirnovin
    Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Neurosurgery 58:ONS96-102; discussion ONS96-102. 2006
    ..This study details our technique and experience in performing microelectrode recording (MER) guided subthalamic nucleus (STN) DBS in the treatment of Parkinson disease...
  101. ncbi Electrophysiological mapping of cat primary auditory cortex with multielectrode arrays
    Seung Jae Kim
    The Department of Bioengineering, The University of Utah, Salt Lake City, UT 84112, USA
    Ann Biomed Eng 34:300-9. 2006
    ..53 +/- 0.08 octave per millimeter. This study demonstrates the use of high electrode count, microelectrode array recordings in characterizing the spatial distribution of acoustic information in the feline AI...

Research Grants76

  1. Lateral Rectus Reanimation following Sixth Nerve Palsy
    Arthur Rosenbaum; Fiscal Year: 2006
    ..muscle will be temporarily dennervated through metered injections of Botox, and will be stimulated with implanted electrodes using the MFT frame as a platform...
  2. DIRECT BRAIN INTERFACE BASED ON EVENT DETECTION IN ECOG
    SIMON LEVINE; Fiscal Year: 2005
    ..implementation and testing with subjects at the University of Michigan and Henry Ford Hospitals who have implanted electrodes for purposes related to epilepsy surgery...
  3. TIME-INTENSITY PATTERNS IN ELECTRICAL STIMULATION
    Robert Shannon; Fiscal Year: 2001
    ..listeners is due to the differences in individual nerve survival and to differences in the coupling of the implanted electrodes to those surviving neurons...
  4. Imaging Neuronal Activity using Electrical Impedance Tomography
    David Holder; Fiscal Year: 2007
    ..validate the physiological basis of this method by recording these fast impedance changes in animals with implanted electrodes, during evoked normal activity...
  5. Multifunction Prosthesis Control using Implanted Sensors
    Richard Weir; Fiscal Year: 2007
    ..will use fuzzy-logic to decipher user intent from telemetry sent over a transcutaneous magnetic link by the implanted electrodes. The same link will provide power for the implanted electrodes. ...
  6. Gustatory Processing and Satiety
    Sidney A Simon; Fiscal Year: 2010
    ..record the activity of neuronal ensemble in all four of these areas fromrats with chronically implanted electrodes that tick to obtain rewarding tastants and whose motivation, as it pertains to their state of hunger or ..
  7. Gustatory Processing and Satiety
    SIDNEY SIMON; Fiscal Year: 2007
    ..record the activity of neuronal ensemble in all four of these areas from rats with chronically implanted electrodes that tick to obtain rewarding tastants and whose motivation, as it pertains to their state of hunger or ..
  8. Method for In-Vivo Assessment of Neuronal Dysfunction
    Miguel Nicolelis; Fiscal Year: 2007
    ..that several well-isolated single units and multi-unit activity can be obtained from a very high number of implanted electrodes. Concomitantly, we have also measured local field potentials (LFP) in the same areas by low-pass filtering ..
  9. MULTICHANNEL IMPLANTABLE SYSTEM FOR NEURAL CONTROL
    P Peckham; Fiscal Year: 2002
    ..to be implemented consists of an external control unit, a multichannel implanted stimulator-telemeter, and implanted electrodes which sense muscle activity (a myoelectric signal)...
  10. Pilot Study of DBS for Treatment-Refractory OCD
    Herbert Ward; Fiscal Year: 2006
    ..data on the effectiveness, safety, and tolerability of chronic electrical stimulation (DBS) via bilaterally implanted electrodes in the anterior limb of the internal capsules of six cases of 'malignant' treatment-refractory OCD that ..
  11. NEUROPROSTHESIS PERFORMANCE - NERVE CUFF ELECTRODES
    Ronald Triolo; Fiscal Year: 2005
    ..Intermittent and cyclic stimulation to individual contacts of chronically implanted electrodes on the distal peripheral nerve branches innervating the vastus lateralis and intermedius will allow fibers ..
  12. Motor Control Deficits in Parkinson's Disease
    Howard Poizner; Fiscal Year: 2009
    ..the same patients, PD patients will be tested ON versus OFF DA replacement prior to their having surgically implanted electrodes, and again after surgery ON and OFF deep brain stimulation (and off medications)...
  13. Motor Control Deficits in Parkinson's Disease
    Howard Poizner; Fiscal Year: 2010
    ..the same patients, PD patients will be tested ON versus OFF DA replacement prior to their having surgically implanted electrodes, and again after surgery ON and OFF deep brain stimulation (and off medications)...
  14. Improving chronic neural recording performance through biomaterial strategies
    Xinyan Tracy Cui; Fiscal Year: 2010
    ..The implanted electrodes cause progressive brain tissue responses including neuronal loss and inflammatory gliosis, which may lead ..
  15. Improving chronic neural recording performance through biomaterial strategies
    Xinyan Cui; Fiscal Year: 2009
    ..The implanted electrodes cause progressive brain tissue responses including neuronal loss and inflammatory gliosis, which may lead ..
  16. Multisite, intrafascicular stimulation for stance
    RICHARD NORMANN; Fiscal Year: 2007
    ..2) Because the tips of the implanted electrodes are in close proximity to the motor neurons, electrical currents required for stimulation are very low...
  17. Motor Control Deficits in Parkinson's Disease
    Howard Poizner; Fiscal Year: 2007
    ..the same patients, we will test PD patients ON versus OFF DA replacement prior to their having surgically implanted electrodes, and again after surgery ON and OFF deep brain stimulation (and off medications)...
  18. Optical Coherence Domain Reflectometry in Brain Probes
    Ali Rezai; Fiscal Year: 2004
    ..Refined guidance would greatly enhance the effectiveness and safety of deep-brain stimulation (DBS) with implanted electrodes. DBS is an FDA-approved treatment for Parkinson's disease and essential tremor that provides long-term ..