copper intrauterine devices

Summary

Summary: Intrauterine contraceptive devices that depend on the release of metallic copper.

Top Publications

  1. ncbi [The role of copper-releasing intrauterine device or levonorgestrel-releasing intrauterine system on uterine bleeding and iron status (prospective study of 8 years)]
    F Imperato
    II Facolta di Medicina e Chirurgia, Istituto di Ostetricia e Ginecologia, Universita degli Studi La Sapienza, Rome, Italy
    Minerva Ginecol 54:271-8. 2002
  2. ncbi IUDs: which device?
    Jo Dennis
    Abacus Centres for Family Planning and Reproductive Health, Liverpool, UK
    J Fam Plann Reprod Health Care 28:61-8. 2002
  3. ncbi Mechanisms of action of intrauterine devices: update and estimation of postfertilization effects
    Joseph B Stanford
    Department of Family and Preventive Medicine, University of Utah Health Research Center, Salt Lake City 84108, USA
    Am J Obstet Gynecol 187:1699-708. 2002
  4. ncbi Assessment of menstrual blood loss in Brazilian users of the frameless copper-releasing IUD with copper surface area of 330 mm2 and the frameless levonorgestrel-releasing intrauterine system
    A T L Andrade
    Maternidade Therezinha de Jesus, Centro de Biologia da Reprodução, Universidade Federal, Juiz de Fora, Brazil
    Contraception 70:173-7. 2004
  5. ncbi Use of copper intrauterine devices and the risk of tubal infertility among nulligravid women
    D Hubacher
    Family Health International, Research Triangle Park, NC 27709, USA
    N Engl J Med 345:561-7. 2001
  6. ncbi TCu 380A IUD: a reversible permanent contraceptive method in women over 35 years of age
    Luis Bahamondes
    Human Reproduction Unit, Department of Obstetrics and Gynecology, School of Medicine, Universidade Estadual de Campinas UNICAMP, Campinas 13084 971, Brazil
    Contraception 72:337-41. 2005
  7. ncbi Ectopic pregnancy among non-medicated and copper-containing intrauterine device users: a 10-year follow-up
    Sanjay Ganacharya
    Department of Obstetrics and Gynecology, Medical and Health Science Center, University of Debrecen, P O Box 37, Nagyerdei krt 98, H 4012 Debrecen, Hungary
    Eur J Obstet Gynecol Reprod Biol 111:78-82. 2003
  8. ncbi Cochrane systematic reviews of IUD trials: lessons learned
    David A Grimes
    Family Health, International, P O Box 13950, Research Triangle Park, NC 27796, USA
    Contraception 75:S55-9. 2007
  9. ncbi New frameless and framed intrauterine devices and systems - an overview
    Dirk Wildemeersch
    Contrel Research, Technology Park, University of Ghent, 9000 Ghent, Belgium
    Contraception 75:S82-92. 2007
  10. ncbi Effect of different contraceptive methods on the oxidative stress status in women aged 40 48 years from the ELAN study in the province of Liege, Belgium
    J Pincemail
    Department of Cardiovascular Surgery, University of Liege, CHU Sart Tilman, 4000 Liege, Belgium
    Hum Reprod 22:2335-43. 2007

Research Grants

  1. Prophylactic Ibuprofen: Effect on IUD Continuation Rates
    David Hubacher; Fiscal Year: 2003
  2. Infrastructure for Population Research at Princeton
    James Trussell; Fiscal Year: 2007
  3. Obesity, Oral Contraception and Ovarian Suppression
    Carolyn Westhoff; Fiscal Year: 2007
  4. Contraceptive Services/Primary Care to Prevent Birth Defects
    Eleanor Schwarz; Fiscal Year: 2007
  5. Harnessing Health IT to Prevent Medication-Induced Birth Defects
    Eleanor Schwarz; Fiscal Year: 2007
  6. Demography Training at Princeton
    James Trussell; Fiscal Year: 2007
  7. Training in Epidemiology and Clinical Trials (TECT)
    David Grimes; Fiscal Year: 2007
  8. Clinical Research in Human Fertility
    Joseph Stanford; Fiscal Year: 2005
  9. RCT of a Novel Oral Contraceptive Initiation Method
    Carolyn Westhoff; Fiscal Year: 2004
  10. ESTIMATING EFFICACY OF A MEDICAL INTERVENTION
    James Trussell; Fiscal Year: 2001

Detail Information

Publications130 found, 100 shown here

  1. ncbi [The role of copper-releasing intrauterine device or levonorgestrel-releasing intrauterine system on uterine bleeding and iron status (prospective study of 8 years)]
    F Imperato
    II Facolta di Medicina e Chirurgia, Istituto di Ostetricia e Ginecologia, Universita degli Studi La Sapienza, Rome, Italy
    Minerva Ginecol 54:271-8. 2002
    ..The authors evaluated the effect of copper surface area on uterine bleeding...
  2. ncbi IUDs: which device?
    Jo Dennis
    Abacus Centres for Family Planning and Reproductive Health, Liverpool, UK
    J Fam Plann Reprod Health Care 28:61-8. 2002
  3. ncbi Mechanisms of action of intrauterine devices: update and estimation of postfertilization effects
    Joseph B Stanford
    Department of Family and Preventive Medicine, University of Utah Health Research Center, Salt Lake City 84108, USA
    Am J Obstet Gynecol 187:1699-708. 2002
    ....
  4. ncbi Assessment of menstrual blood loss in Brazilian users of the frameless copper-releasing IUD with copper surface area of 330 mm2 and the frameless levonorgestrel-releasing intrauterine system
    A T L Andrade
    Maternidade Therezinha de Jesus, Centro de Biologia da Reprodução, Universidade Federal, Juiz de Fora, Brazil
    Contraception 70:173-7. 2004
    ..Heavy and abnormal MBL is the main reason for discontinuation of intrauterine devices...
  5. ncbi Use of copper intrauterine devices and the risk of tubal infertility among nulligravid women
    D Hubacher
    Family Health International, Research Triangle Park, NC 27709, USA
    N Engl J Med 345:561-7. 2001
    ..The concern that IUDs that contain copper--currently the most commonly used type--may increase the risk of infertility in nulligravid women has limited the use of this highly effective method of birth control...
  6. ncbi TCu 380A IUD: a reversible permanent contraceptive method in women over 35 years of age
    Luis Bahamondes
    Human Reproduction Unit, Department of Obstetrics and Gynecology, School of Medicine, Universidade Estadual de Campinas UNICAMP, Campinas 13084 971, Brazil
    Contraception 72:337-41. 2005
    ..The objective of the study was to evaluate the performance of the TCu 380A IUD in women who had been using the device for more than 10 years and who were 35 years of age or more on completion of the 10th year of IUD use...
  7. ncbi Ectopic pregnancy among non-medicated and copper-containing intrauterine device users: a 10-year follow-up
    Sanjay Ganacharya
    Department of Obstetrics and Gynecology, Medical and Health Science Center, University of Debrecen, P O Box 37, Nagyerdei krt 98, H 4012 Debrecen, Hungary
    Eur J Obstet Gynecol Reprod Biol 111:78-82. 2003
    ..To compare ectopic pregnancy (EP) rates among users of non-medicated and copper-containing IUDs...
  8. ncbi Cochrane systematic reviews of IUD trials: lessons learned
    David A Grimes
    Family Health, International, P O Box 13950, Research Triangle Park, NC 27796, USA
    Contraception 75:S55-9. 2007
    ..Intrauterine devices (IUDs) are the most widely used reversible contraceptives in the world today, and decisions about their use should reflect the best available evidence...
  9. ncbi New frameless and framed intrauterine devices and systems - an overview
    Dirk Wildemeersch
    Contrel Research, Technology Park, University of Ghent, 9000 Ghent, Belgium
    Contraception 75:S82-92. 2007
    ..In some women, the use of misoprostol 400 microg, 3 h prior to fitting of the IUD/IUS, may be useful to dilate the cervical canal. The popularity of the IUD could be much improved if attention is given to this aspect of IUD insertion...
  10. ncbi Effect of different contraceptive methods on the oxidative stress status in women aged 40 48 years from the ELAN study in the province of Liege, Belgium
    J Pincemail
    Department of Cardiovascular Surgery, University of Liege, CHU Sart Tilman, 4000 Liege, Belgium
    Hum Reprod 22:2335-43. 2007
    ..Among conditions known to influence oxidative stress, the use of oral contraception (OC) in women has been a matter of ongoing discussion...
  11. ncbi Randomized comparison of levonorgestrel- and copper-releasing intrauterine systems immediately after abortion, with 5 years' follow-up
    Paivi Pakarinen
    Steroid Research Laboratory, Biochemistry, Institute of Biomedicine, Biomedicum, University of Helsinki, Helsinki, Finland
    Contraception 68:31-4. 2003
    ..Mirena was more effective and the rate of adverse events was lower than with NovaT. Special attention should be paid to the insertion procedure when carried out at the time of abortion...
  12. ncbi The 'frameless' intrauterine system for long-term, reversible contraception: a review of 15 years of clinical experience
    Dirk Wildemeersch
    Contrel Research, Technology Park, University of Ghent, Belgium
    J Obstet Gynaecol Res 29:164-73. 2003
    ..The development of the 'frameless' intrauterine system (IUS) is a response to the growing need to develop high-performing, long-acting, reversible, and acceptable contraceptives with a high continuation of use...
  13. ncbi [Inconveniences and complications after insertion of IUDs by general practitioners]
    Jytte Rothmann Johansen
    København Universitet, Institut for Folkesundhedsvidenskab, Afdeling for Almen Medicin, København
    Ugeskr Laeger 166:3190-4. 2004
  14. ncbi IUD In Situ?
    Colleen Dy
    J Obstet Gynaecol Can 30:107-8. 2008
  15. ncbi [Non hormonal contraception]
    Geoffroy Robin
    Service de gynécologie médicale et médecine du couple, Hopital Jeanne de Flandre, CHRU de Lille, 59037 Lille
    Rev Prat 58:29-40. 2008
    Excluded hormonal contraceptives, there are non hormonal means of contraception. Among them, copper intrauterine devices (IUD) are very efficient...
  16. ncbi Removal of copper-bearing IUDs in asymptomatic patients. Reply
    Jyoti Jatti
    J Fam Plann Reprod Health Care 34:136. 2008
  17. doi Options for intrauterine contraception
    Heidi Collins Fantasia
    William F Connell School of Nursing, Boston College, Chestnut Hill, MA, USA
    J Obstet Gynecol Neonatal Nurs 37:375-83. 2008
    ..A greater understanding of the benefits and limitations of these two contraceptive options will assist women's health care providers to better meet the family planning needs of their patients...
  18. ncbi Sonographic and Doppler flow characteristics of levonorgestrel and copper-releasing intrauterine devices
    Yaron Zalel
    Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Israel
    MedGenMed 5:38. 2003
  19. ncbi A randomized trial on the clinical performance of Nova T380 and Gyne T380 Slimline copper IUDs
    Tommy Haugan
    Department of Epidemiology, SINTEF Health Research, N 7465 Trondheim, Norway
    Contraception 75:171-6. 2007
    The objective of this open randomized study was to compare the clinical performance of Nova T380 and Gyne T380 Slimline copper intrauterine devices (IUDs).
  20. ncbi [Weight variation in users of the levonorgestrel-releasing intrauterine system, of the copper IUD and of medroxyprogesterone acetate in Brazil]
    Daniela Angerame Yela
    Departamento de Obstetricia e Ginecologia, Faculdade de Medicina, Universidade Estadual de Campinas UNICAMP, Campinas, Brazil
    Rev Assoc Med Bras 52:32-6. 2006
    ....
  21. ncbi Effect of a levonorgestrel intrauterine system on women with type 1 diabetes: a randomized trial
    Svetlana Rogovskaya
    Research Center of Obstetrics, Gynecology, and Perinatology, Russian Academy of Medical Science, Moscow, Russia
    Obstet Gynecol 105:811-5. 2005
    ..To examine the effect of the levonorgestrel-releasing intrauterine system on glucose metabolism in diabetic women...
  22. ncbi Transuterine migration as a complication of intrauterine contraceptive devices: six case reports
    Y A Tuncay
    SSK Goztepe Educational Hospital, Clinic of Obstetrics and Gynecology, Istanbul, Turkey
    Eur J Contracept Reprod Health Care 9:194-200. 2004
    ..Although an IUD is an effective contraceptive method, the migration of one is a rare but serious complication. The aim of this report is to emphasize the management and therapy of this complication...
  23. ncbi [Effects of intrauterine contraceptive device on expression of vascular endothelial growth factor, kinase insert domain-containing receptor and microvessel density in endometrium]
    Zhi Min Xin
    Reproductive Medical Center, First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China
    Zhonghua Fu Chan Ke Za Zhi 39:771-5. 2004
    ....
  24. ncbi Attitudes of Israeli gynecologists towards the levonorgestrel-releasing intrauterine system: a questionnaire survey
    A Ben-Haroush
    Department of Obstetrics and Gynecology, Rabin Medical Center, Petach Tiqva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Contracept Reprod Health Care 9:29-33. 2004
    ..In addition, physician knowledge of patient satisfaction with the device was evaluated...
  25. ncbi Contraception for the older woman: an update
    R K Bhathena
    Department of Obstetrics and Gynaecology, Petit Parsee General and Masina Hospitals, Bombay, India
    Climacteric 9:264-76. 2006
    ..The woman should be provided with individualized advice so that she has a choice between the newer, effective, largely safe, reversible methods and sterilization...
  26. ncbi The intrauterine device: rethinking old paradigms
    Katherine W Morgan
    University of Utah College of Nursing, 10 South 2000 East, Salt Lake City, UT 84112, USA
    J Midwifery Womens Health 51:464-70. 2006
    ..In light of this data, the IUD should be made available to women at low-risk for sexually-transmitted infections and should not be denied to women on the basis of parity or marital status...
  27. ncbi Intrauterine contraception: the role of general practitioners in four Dutch general practices
    Annika A G Vos
    Women s Studies in Medicine, Department of General Practice, University of Nijmegen, Nijmegen, The Netherlands
    Contraception 69:283-7. 2004
    ..General practitioners clearly follow their own opinions about inserting IUD in nulliparous women. Currently, general practitioners are prescribing more Multiload Cu 375 IUDs and levonorgestrel-releasing IUDs...
  28. ncbi Clinical outcomes of early postplacental insertion of intrauterine contraceptive devices
    Sevki Celen
    Zekai Tahir Burak Women Health Education and Research Hospital, Ankara, Turkey
    Contraception 69:279-82. 2004
    ..To assess the efficacy, safety and, thus, advantages and disadvantages, of early postplacental intrauterine device (IUD) insertion...
  29. ncbi Surgical management of intra-abdominal mislocated intrauterine devices
    Mahmut T Ozgun
    Department of Obstetrics and Gynecology, Faculty of Medicine, Gevher Nesibe Hospital, Erciyes University, 38039 Kayseri, Turkey
    Contraception 75:96-100. 2007
    ..We report on our experience in surgical treatment of patients with intra-abdominal intrauterine devices (IUDs)...
  30. ncbi Problems in the conduct and analysis of "A comparative randomized study of three different IUDs in nulliparous Mexican women"
    Irving Sivin
    Contraception 69:259-60. 2004
  31. doi Intrauterine contraception: an update
    R K Bhathena
    Department of Obstetrics and Gynaecology, B D Petit Parsee General and Masina Hospitals, Bombay, India
    J Obstet Gynaecol 28:262-5. 2008
  32. ncbi Insertion of intrauterine devices: a comparison of experience with Mirena and Multiload Cu 375 during post-marketing monitoring in New Zealand
    Mira Harrison-Woolrych
    Intensive Medicines Monitoring Programme, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    N Z Med J 116:U538. 2003
    ..To compare the incidence of reported insertion problems with the levonorgestrel-releasing intrauterine device (Mirena) with that of the copper device Multiload Cu 375...
  33. ncbi Contraception and treatment in the perimenopause with a novel "frameless" intrauterine levonorgestrel-releasing drug delivery system: an extended pilot study
    D Wildemeersch
    Contrel Research, Technology Park Zwijnaarde, Ghent, Belgium
    Contraception 66:93-9. 2002
    ....
  34. ncbi Efficacy of a mini version of the frameless GyneFix intrauterine system (IUS) with effective copper surface area of 200 mm2. dirk.wildemeersch@contrel.be
    Dirk Wildemeersch
    Contrel Research, Ghent, Belgium
    Contraception 66:237-41. 2002
    ..This is made possible by anchoring the active contraceptive substance to the fundus of the uterus. The fact that 100% of the copper surface area of the frameless IUS is available for copper release is an additional advantage...
  35. ncbi Insertion of an intrauterine contraceptive device after induced or spontaneous abortion: a review of the evidence
    N L Stanwood
    Robert Wood Johnson Clinical Scholars Program, University of North Carolina School of Medicine, Chapel Hill, USA
    BJOG 108:1168-73. 2001
    ..Immediate insertion may have a higher expulsion rate than delayed insertion. However, these risks may be outweighed by the benefit of immediate contraception...
  36. ncbi Outcomes at 1 year for the first 200 patients fitted with GyneFix at Margaret Pyke Centre
    T Masters
    Avon Brook, Bristol, UK
    Eur J Contracept Reprod Health Care 7:65-70. 2002
    ..However, they are perhaps not as good as had been anticipated for this revolutionary new intrauterine implant. Possible reasons for this are explored...
  37. ncbi [Intrauterine devices in general practice: a prospective study of 300 insertions]
    H Marret
    Département de gynécologie obstétrique, Medecine Foetale et Reproduction Humaine, Hopital Bretonneau, 2, boulevard Tonnelle, 37044 Tours Cedex 1, France
    J Gynecol Obstet Biol Reprod (Paris) 31:465-70. 2002
    To assess the effectiveness of management practices of copper intrauterine devices (IUD) in general medicine.
  38. ncbi [Use of 3-dimensional ultrasound for assessment of intrauterine device position]
    I Hösli
    Geburtshilfe und Schwangerschaftsmedizin, Universitats Frauenklinik Basel
    Ultraschall Med 22:75-80. 2001
    ..The purpose of our prospective study was to assess the accuracy of measuring and visualizing different types of IUDs with three dimensional ultrasound (3D) and two dimensional ultrasound (2D)...
  39. ncbi The local progestational effect of the levonorgestrel-releasing intrauterine system: a sonographic and Doppler flow study
    Y Zalel
    Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer, Israel
    Hum Reprod 17:2878-80. 2002
    ..We aimed to evaluate the effect of the levonorgestrel-releasing intrauterine system (LNG-IUS) on the uterine vasculature and the endometrium...
  40. ncbi Extending the time limit for starting the Yuzpe regimen of emergency contraception to 120 hours
    Charlotte Ellertson
    Ibis Reproductive Health, Cambridge, Massachusetts 02138, USA
    Obstet Gynecol 101:1168-71. 2003
    ..The purpose of this study was to determine whether the window for emergency hormonal contraception can be extended to 120 hours...
  41. doi State-of-the-art of non-hormonal methods of contraception: III. Intrauterine devices
    Irving Sivin
    Population Council, New York, NY10065, USA
    Eur J Contracept Reprod Health Care 15:96-112. 2010
    ..Yet other research lines indicate noncontraceptive benefits of copper intrauterine devices in protecting against endometrial cancer, and favourable risk-benefit analyses of IUD use by women at ..
  42. doi Efficacy of contraceptive methods: A review of the literature
    Diana Mansour
    New Croft Centre, Newcastle upon Tyne, UK
    Eur J Contracept Reprod Health Care 15:4-16. 2010
    ..To provide a comprehensive and objective summary of contraceptive failure rates for a variety of methods based on a systematic review of the literature...
  43. ncbi Copper hypersensitivity: dermatologic aspects--an overview
    Jurij J Hostynek
    Euromerican Technology Resources, Inc, Lafayette, California 94549, USA
    Rev Environ Health 18:153-83. 2003
    ..systemic allergic reactions (SAR) and contact stomatitis (STO), but considering the widespread use of copper intrauterine devices (IUDs) and the importance of copper in coinage, items of personal adornment and industry, unambiguous ..
  44. ncbi [Reasons for removal of intrauterine devices among women in general practice]
    Line Kolding
    Kvindeafdelingen, Regionshospitalet Viborg, Heibergs Alle 4, 8800 Viborg, Denmark
    Ugeskr Laeger 175:884-6. 2013
    ..In general the women were satisfied with both types of IUDs. More women with copper-releasing IUDs had an early removal because of complaints than women with levonorgestrel-releasing IUDs...
  45. ncbi Insertion and removal of intrauterine devices
    Brett Andrew Johnson
    Methodist Charlton Medical Center, Dallas, Texas 75237, USA
    Am Fam Physician 71:95-102. 2005
    ..The IUD is inserted into the uterus according to individual protocols, with the threads cut at a length to allow the patient to check the device's position. Expulsion may occur with both types of IUDs...
  46. ncbi Copper intrauterine device use by nulliparous women: review of side effects
    David Hubacher
    Family Health International, PO Box 13950, Research Triangle Park, NC 27709, USA
    Contraception 75:S8-11. 2007
    ..Nulliparity was once a relative contraindication to using the copper IUD. However, new research and changes in product labeling have eased safety concerns. Side effects remain a major problem with copper IUD use in this population...
  47. ncbi [Random comparative study between intrauterine device Multiload Cu375 and TCu 380a inserted in the postpartum period]
    Roger Lara Ricalde
    Departamento de planificación familiar del Instituto Naciónal de Perinatología Lomas Virreyes, Mexico
    Ginecol Obstet Mex 74:306-11. 2006
    ..To evaluate safety and effectiveness of the intrauterine device Multiload Cu375 compared with the TCu 380A inserted in the postpartum period...
  48. doi Can intrauterine contraceptive devices be a Candida albicans reservoir?
    Francieli Chassot
    Division of Clinical Cytology, Teaching and Research in Clinical Analysis Laboratory, State University of Maringa, Maringa, Parana, Brazil
    Contraception 77:355-9. 2008
    ..The in vitro adherence of Candida albicans isolated from vaginal exudates of patients with vulvovaginal candidiasis (VVC) to intrauterine contraceptive devices (IUDs) and biofilm formation capacity were evaluated...
  49. pmc Contraception and HIV infection in women
    Oskari Heikinheimo
    Department of Obstetrics and Gynaecology, University of Helsinki, Finland
    Hum Reprod Update 15:165-76. 2009
    ..This review aims to show the effect of contraceptive choices on risk of HIV and on the course of disease in women with HIV...
  50. ncbi Persistent subumbilical discharge associated with actinomycosis caused by intrauterine contraceptive device: a case report
    Ibrahim Polat
    Gynecological Clinic, Istanbul Bakirkoy Woman and Children Hospital, Istanbul, Turkey
    Arch Gynecol Obstet 277:457-60. 2008
    ..We recommend consideration of this minor possibility during evaluation of women with chronic abdominal discharge...
  51. doi Pyosalpinx caused by the tubal migration of an intrauterine device--a case report
    Suna Ozdemir
    Department of Gynaecology and Obstetrics, Meram Medical Faculty, Selcuk University, Konya, Turkey
    Eur J Contracept Reprod Health Care 13:320-2. 2008
    ..Tubal migration of an IUD is extremely rare and little is known about its mechanism. We describe a case of pyosalpinx caused by the tubal migration of a copper IUD. The tail of the device was embedded in the mesocolon...
  52. ncbi Health care providers' knowledge of, attitudes toward and provision of emergency contraceptives in Lagos, Nigeria
    Olufunke Margaret Ebuehi
    Institute of Child Health and Primary Care, Department of Biochemistry, College of Medicine, University of Lagos, Lagos, Nigeria
    Int Fam Plan Perspect 32:89-93. 2006
    ..Emergency contraception can play an important role in reducing the rate of unintended pregnancies in Nigeria. Although it is included in the national family planning guidelines, there is limited awareness of this method among clients...
  53. doi Strategies to prevent unintended pregnancy: increasing use of long-acting reversible contraception
    P D Blumenthal
    Department of Obstetrics and Gynecology, Stanford University, Stanford, CA 94305 5317, USA
    Hum Reprod Update 17:121-37. 2011
    ..In this review we aim to discuss the role of LARC methods and importance of contraceptive counseling in reducing unintended pregnancy rates...
  54. doi Release behavior of cupric ions for TCu380A and TCu220C IUDs
    Bianmei Cao
    School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, People s Republic of China
    Biomed Mater 3:044114. 2008
    ..The main compounds identified were cuprite (Cu(2)O). Copper wire and copper tubes were implanted in the uteruses of rats. In vivo experiments were also done. The corrosion rate in vivo was higher than that in vitro...
  55. doi Intrauterine device use among women with uterine fibroids: a systematic review
    Lauren B Zapata
    Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Contraception 82:41-55. 2010
    ....
  56. doi Intrauterine contraceptives that do not fit well contribute to early discontinuation
    Dirk Wildemeersch
    Contrel Research, Technology Park, University of Ghent, Ghent, Belgium
    Eur J Contracept Reprod Health Care 16:135-41. 2011
    To shed additional light on various aspects of intrauterine contraception discussed recently in a comprehensive review article and on the continued development of frameless copper intrauterine devices (IUDs).
  57. ncbi [Effects of herb therapy for benefiting qi and removing blood stasis on ultrastructure of vascular endothelial cells and vascular smooth muscle cells of uterine endometrium in rabbits with copper intrauterine device]
    Lei Lei
    Department of Integrated Traditional Chinese and Western Medicine, Hunan College of Traditional Chinese Medicine, Changsha, Hunan Province 410007, China
    Zhong Xi Yi Jie He Xue Bao 4:60-3. 2006
    ....
  58. ncbi A comparative study of the levonorgestrel-releasing intrauterine system Mirena versus the Copper T380A intrauterine device during lactation: breast-feeding performance, infant growth and infant development
    Ayman H Shaamash
    Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt
    Contraception 72:346-51. 2005
    ..Mirena is a levonorgestrel-releasing intrauterine system (LNG-IUS) that provides highly effective and long-acting progestogen-only contraception...
  59. ncbi The intrauterine device in modern contraception: Still an actuality?
    Andrea Tinelli
    Department of Obstetrics and Gynecology, Vito Fazzi Hospital, Lecce, Italy
    Eur J Contracept Reprod Health Care 11:197-201. 2006
    ....
  60. ncbi Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen
    David Hubacher
    Family Health International, Research Triangle Park, NC, USA
    Am J Obstet Gynecol 195:1272-7. 2006
    ..This study was undertaken to determine whether 400 mg of prophylactic ibuprofen can alleviate pain from insertion of an intrauterine device (IUD) and to measure level of pain with improved techniques...
  61. doi Variations in body mass index of users of depot-medroxyprogesterone acetate as a contraceptive
    Márcia Pantoja
    Human Reproduction Unit, Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas UNICAMP, and National Institute of Hormones and Women Health, Campinas, SP 13084 971, Brazil
    Contraception 81:107-11. 2010
    ..Weight gain is a frequent reason for discontinuing the contraceptive with depot-medroxyprogesterone acetate (DMPA)...
  62. ncbi Copper-T intrauterine device and levonorgestrel intrauterine system: biological bases of their mechanism of action
    María Elena Ortiz
    Instituto Chileno de Medicina Reproductiva, Postal code 6500970, Santiago, Chile
    Contraception 75:S16-30. 2007
    ..The common belief that the usual mechanism of action of IUDs in women is destruction of embryos in the uterus is not supported by empirical evidence...
  63. ncbi Transverse limb reduction and intrauterine device: case report and review of the literature
    Alina Weissmann-Brenner
    Helen Schneider Hospital for Women, Rabin Medical Center, Campus Beilinson, Petah Tiqva, Israel
    Eur J Contracept Reprod Health Care 12:294-7. 2007
    ..Pregnancies with an intrauterine device (IUD) in situ are associated with increased maternal and foetal morbidity and mortality. No proven teratogenetic effects have been attributed to IUDs...
  64. ncbi Contraception
    G R Huggins
    Francis Scott Key Medical Center, Baltimore, Maryland
    Curr Opin Obstet Gynecol 2:291-5. 1990
    ..However, the risk was overstated earlier. Women who have only 1 sexual partner in their lifetime had no significant risk of tubal infertility. "lost" IUDs continue to be a problem...
  65. ncbi Reaching providers is not enough to increase IUD use: a factorial experiment of 'academic detailing' in Kenya
    Jennifer Wesson
    Family Health International, North Carolina, USA
    J Biosoc Sci 40:69-82. 2008
    ..However, the cost of the detailing in comparison to the small number of IUDs inserted indicates that this intervention is not cost-effective...
  66. doi Effects of Mirena (levonorgestrel-releasing intrauterine system) and Ortho Gynae T380 intrauterine copper device on lipid metabolism--a randomized comparative study
    Ying Woo Ng
    Department of Obstetrics and Gynaecology, National University Hospital, Singapore 119074, Singapore
    Contraception 79:24-8. 2009
    ..This study aims to assess the effects of levonorgestrel-releasing intrauterine system (LNG-IUS) on lipid metabolism in an Asian population using Ortho Gynae T380 copper containing (nonhormonal) intrauterine device (IUD) as a control...
  67. doi The cost-effectiveness of long-acting reversible contraceptive methods in the UK: analysis based on a decision-analytic model developed for a National Institute for Health and Clinical Excellence (NICE) clinical practice guideline
    I Mavranezouli
    National Collaborating Centre for Women s and Children s Health NCC WCH, Royal College of Obstetricians and Gynaecologists, London, UK
    Hum Reprod 23:1338-45. 2008
    ..However, their uptake is low in much of the developed world. This study aimed at assessing the cost-effectiveness of LARC methods from the British National Health Service (NHS) perspective...
  68. ncbi The acceptance rate of intrauterine contraceptive device (IUCD) amongst family planning clinic users in Lagos University Teaching Hospital (LUTH)
    O Adegbola
    Department of Obstetrics and Gynaecology, College of Medicine, University of Lagos, Lagos University Teaching Hospital, Lagos
    Nig Q J Hosp Med 18:175-80. 2008
    ..Intrauterine Contraceptive Device is an effective reversible long-term contraceptive method that is popular and widely used in this environment...
  69. doi Do users of the intrauterine system (Mirena) have different genital symptoms and vaginal flora than users of the intrauterine contraceptive device?
    R Neale
    Department of Genitourinary Medicine, Royal Cornwall Hospital NHS Trust, Truro, Cornwall TR1 3LJ, UK
    Int J STD AIDS 20:423-4. 2009
    ..More women with an IUCD developed BV compared with an IUS at 4-6 weeks and six months. However, there were insufficient numbers of women with BV to demonstrate any significant difference between the vaginal flora of the two groups...
  70. doi Intrauterine device insertion during the postpartum period: a systematic review
    Nathalie Kapp
    Department of Reproductive Health and Research, World Health Organization, CH 1211 Geneva 27, Switzerland
    Contraception 80:327-36. 2009
    ..Insertion of an intrauterine device (IUD) at different times or by different routes during the postpartum period may increase the risk of complications...
  71. doi Combined oral contraceptive and intrauterine device use among women with gestational trophoblastic disease
    Mary E Gaffield
    Department of Reproductive Health and Research, World Health Organization, 1211 Geneva 27, Switzerland
    Contraception 80:363-71. 2009
    ..Women diagnosed with gestational trophoblastic disease (GTD) need safe and effective contraception because they are advised to delay a subsequent pregnancy...
  72. doi Effects of a copper-medicated intrauterine device on ovarian artery, uterine artery, and intrauterine blood flow
    O Shen
    Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel
    Gynecol Obstet Invest 66:253-6. 2008
    ..To determine the effect of a copper-medicated intrauterine device (IUD) on ovarian, uterine, arcuate, radial and subendometrial Doppler-derived indices of blood flow...
  73. ncbi Copper T 380A IUD and magnetic resonance imaging
    Miriam Zieman
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA 30303, USA
    Contraception 75:93-5. 2007
    ..Prior testing of the Copper T 380A intrauterine device (IUD) has been done using MR systems of 1.5 T or less. This study was performed to test this IUD in a MR system of 3.0 T...
  74. ncbi Intrauterine contraception: it's not what you think
    Deana Vaughn
    Women s Health Section, TN Department of Health, Nashville, USA
    Tenn Med 99:38, 40. 2006
    ..Our daughters are discovering intrauterine contraception. As their healthcare providers, we are in a position to educate them as they come to the office with questions. We should be prepared to give them current and accurate information...
  75. ncbi Estrogen-progestogen once-a-month injectable contraceptives and serum prolactin
    J Garza-Flores
    Departamento de Biologia, Instituto Nacional de la Nutrición S Zubirán, Mexico City, Mexico
    Contraception 39:519-29. 1989
    ..Overall, the data demonstrated that the chronic administration of these estrogen/progestogen once-a-month injectable contraceptives does not affect the Prl baseline secretion in women...
  76. ncbi Uterine perforation on intrauterine device insertion: is the incidence higher than previously reported?
    Mira Harrison-Woolrych
    Intensive Medicines Monitoring Programme, University of Otago, Dunedin, New Zealand
    Contraception 67:53-6. 2003
    ....
  77. ncbi Study on the effects of FCu-IUD and FICu-IUD on matrix metalloproteinases in human uterine flushing and endometrium
    Wei Li
    Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030
    J Huazhong Univ Sci Technolog Med Sci 22:9-11, 16. 2002
    ....
  78. ncbi Comparative trial of the force required for, and pain of, removing GyneFix versus Gyne-T380S following randomised insertion
    Rachel E D'Souza
    Margaret Pyke Centre, London, UK
    J Fam Plann Reprod Health Care 29:29-31. 2003
    ..To assess the force required for, and pain of, removal of the GyneFix as compared with T-framed intrauterine devices (IUDs)...
  79. ncbi A comparative randomized study of three different IUDs in nulliparous Mexican women
    J B Otero-Flores
    Reproductive Health Coordination, Division of Family Planning Mexican Institute of Social Security IMSS, Mier y Pesado 120, Colonia del Valle, Mexico 03100, DF, Mexico City, Mexico
    Contraception 67:273-6. 2003
    ..5% (+/-0.3) in TCu 380 Nul, and no pregnancy in ML Cu 375 sl (p < 0.05). Especially designed IUDs for nulliparous women had a better clinical profile compared with the standard IUD. This may improve the use of IUD in this population...
  80. ncbi Characterization of copper in uterine fluids of patients who use the copper T-380A intrauterine device
    Veronica Arancibia
    Facultad de Quimica, Pontificia Universidad Catolica de Chile, Chile
    Clin Chim Acta 332:69-78. 2003
    ..However, there is little information about the amount and form of copper in the fluid and whether the presence of this element produces any change in the protein concentration...
  81. ncbi Laparoscopic removal of an intraperitoneal translocated intrauterine contraceptive device
    L Miranda
    Department of General Surgery, Center of Laparoscopic Surgery, Monaldi Hospital, Naples, Italy
    Eur J Contracept Reprod Health Care 8:122-5. 2003
    ..From that time on, she started to complain of the above-mentioned symptoms. She had an abdominal X-ray which revealed the IUD in the abdominal cavity. She then underwent a laparoscopic removal of the translocated IUD...
  82. ncbi Unrecognised perforation of the uterus into bladder by an IUD
    A Honarbakhsh
    Department of Radiology and Ultrasonography, Madaen Hospital, Tehran, Iran
    J Obstet Gynaecol 23:444-5. 2003
  83. ncbi Perforation with the GyneFix intrauterine implant: is there a common factor?
    Thomas R Aust
    Department of Gynaecology, Liverpool Women s Hospital, Liverpool, UK
    J Fam Plann Reprod Health Care 29:155-6. 2003
    ..A review of all other reports of this complication has been performed. Analysis of these reports suggests prolonged amenorrhoea secondary to continuous progestogen use as a possible common predisposing factor...
  84. ncbi Ectopic pregnancy risk when contraception fails. A review
    Lesley Anne Furlong
    U S Food and Drug Administration, HFD 580, 5600 Fishers Lane, Rockville, MD 20857, USA
    J Reprod Med 47:881-5. 2002
    ..To alert clinicians to the risk of ectopic pregnancy when certain contraceptive methods fail by summarizing data from trials reviewed by the U.S. Food and Drug Administration (FDA)...
  85. ncbi Intravesical migration of intrauterine device resulting in stone formation
    rfan H Atakan
    Department of Urology, University of Trakya Faculty of Medicine, Edirne, Turkey
    Urology 60:911. 2002
    ..We report on a 27-year-old woman in whom an intrauterine contraceptive device (Copper-T) migrated from the uterus to the bladder and resulted in formation of a stone...
  86. ncbi Intrauterine devices
    Xiao Bilian
    National Research Institute for Family Planning, No 12 Da Hui Si, Beijing 100081, People s Republic of China
    Best Pract Res Clin Obstet Gynaecol 16:155-68. 2002
    ..The copper IUD is the most effective method for emergency contraception. It can prevent over 95% of unwanted pregnancies within 5 days of unprotected intercourse...
  87. ncbi Late uterine perforation with an anchored IUD, the Gynefix: a case report
    M Vekemans
    Universite Libre de Bruxelles, Brussels, Belgium
    Contraception 60:55-6. 1999
    ..The incidence of this complication is unknown. The appropriateness or need of assessing echo-graphically the myometrial thickness before the insertion and of controlling its correct position after the insertion remains uncertain...
  88. ncbi Magnetic resonance imaging appearances of the Mirena and GyneFix intra-uterine contraceptive devices: a report of two cases
    G H Hall
    Centre for Magnetic Resonance Investigations, University of Hull at Hull Royal Infirmary, Hull, UK
    Br J Fam Plann 26:224-6. 2000
    ....
  89. ncbi Depot medroxyprogesterone acetate and basal serum prolactin levels in lactating women
    S Ratchanon
    Reproductive Medicine and Family Planning Units, Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
    Obstet Gynecol 96:926-8. 2000
    ..To study the effect of depot medroxyprogesterone acetate on basal serum prolactin levels in lactating women...
  90. ncbi Evaluation of postabortion IUD insertion in Egyptian women
    A Moussa
    Department of Obstetrics and Gynecology, Alazhar School of Medicine, Cairo, Egypt
    Contraception 63:315-7. 2001
    ..This study showed that insertion of an IUD immediately after a spontaneous abortion is safe and could be offered to those who have had an abortion and who ask for a method of contraception...
  91. ncbi Copper intrauterine devices and tubal infertility among nulligravid women
    Veronique Verhoeven
    N Engl J Med 346:376-7. 2002
  92. ncbi Noncontraceptive health benefits of intrauterine devices: a systematic review
    David Hubacher
    Family Health International, Research Triangle Park, North Carolina 27709, USA
    Obstet Gynecol Surv 57:120-8. 2002
    ..Like oral contraceptives, intrauterine contraceptives confer important noncontraceptive health benefits...
  93. ncbi Contraceptive efficacy and clinical performance of Nestorone implants in postpartum women
    M R Massai
    Instituto Chileno de Medicina Reproductiva, Consultorio de Planificacion Familiar, J V Lastarria 29, Depto 101, Santiago, Chile
    Contraception 64:369-76. 2001
    ..2%). Concentrations of NES in breast milk ranged between 54-135 pmol/liter. The Nestorone implant is a highly effective contraceptive, safe for breastfed infants because the steroid is inactive by the oral route...
  94. ncbi The effect on intrauterine device position and performance of a modified TCu380A insertion technique
    K Homouda
    Department of Obstetrics and Gynecology, Ain Shams University School of Medicine, Cairo, Egypt
    Eur J Contracept Reprod Health Care 7:31-5. 2002
    ..To assess the validity of modifying the technique of intrauterine device (IUD) placement to decrease the incidence of incorrect positioning within the uterine cavity...
  95. ncbi [A multicentre comparative clinical study of uterine cavity shaped device Cu300, TCu220C and TCu380A in ten years]
    He Ping Chen
    Affiliated Hospital, Chongqing Family Planning Scientific Research Institute, Chongqing 400020, China
    Zhonghua Fu Chan Ke Za Zhi 38:298-301. 2003
    ..To observe the clinical effects of uterine cavity shaped device (UCD) Cu300, TCu220C and TCu380A in ten years...
  96. ncbi Uterine factors and risk of pregnancy in IUD users: a nested case-control study
    Angels Avecilla-Palau
    Centre d Atenció a la Salut Sexual i Reproductiva, Hospital Municipal de Badalona, Badalona Serveis Assistencials, C Mare de Déu de Lorda 119 125, 08915 Badalona, Spain
    Contraception 67:235-9. 2003
    ..The findings suggest that the gynecological characteristics of the woman analyzed should not be a criterion for the selection of potential IUD users...
  97. ncbi Assessment of menstrual blood loss in Belgian users of the frameless copper-releasing IUD with copper surface area of 200 mm2 and users of a copper-levonorgestrel-releasing intrauterine system
    D Wildemeersch
    Contrel Research, Ghent, Belgium
    Contraception 70:169-72. 2004
    ..This study was conducted to evaluate the effect of a miniaturized frameless copper IUD (GyneFix 200 small) and a copper-levonorgestrel (GynePlant) intrauterine system (IUS) on the amount of menstrual blood loss (MBL)...
  98. ncbi The release of cupric ion in simulated uterine: New material nano-Cu/low-density polyethylene used for intrauterine devices
    T Xu
    Materials Center, Guizhou University of Technology, Guiyang, 550003, P R China
    Contraception 70:153-7. 2004
    ..The aim of this study was to investigate copper ion release from this composite as a basis for considering its used in an IUD...
  99. ncbi Pre-malignant and malignant cervical pathologies among inert and copper-bearing intrauterine contraceptive device users: a 10-year follow-up study
    Sanjay Ganacharya
    Department of Obstetrics and Gynaecology, Medical and Health Science Centre, University of Debrecen, Debrecen, Hungary
    Eur J Contracept Reprod Health Care 11:89-97. 2006
    ..The aim of the study was to compare the incidence of pre-malignant and malignant cervical conditions during a period of 10 years of use of inert (Szontagh) and copper-bearing IUCDs...
  100. ncbi Expulsion of part of a spontaneously broken IUCD
    P Sinha
    Conquest Hospital, St Leonards on Sea, East Sussex TN37 7RD, UK
    J Obstet Gynaecol 24:837-8. 2004
  101. ncbi Intrauterine contraceptive devices and risk of pelvic inflammatory disease: standard of care in high STI prevalence settings
    Richard Steen
    Reprod Health Matters 12:136-43. 2004
    ..Even with safe insertion, IUD promotion in areas of high STI/HIV prevalence must address women's needs for dual protection from infection and unwanted pregnancy...

Research Grants24

  1. Prophylactic Ibuprofen: Effect on IUD Continuation Rates
    David Hubacher; Fiscal Year: 2003
    ..In the US, ibuprofen may help spur renewed interest in the most cost effective and efficacious reversible contraceptive method available. ..
  2. Infrastructure for Population Research at Princeton
    James Trussell; Fiscal Year: 2007
    ..The journal Future of Children will promote effective policies and programs for children by providing policymakers, service providers, and the media with information based on the best available research. ..
  3. Obesity, Oral Contraception and Ovarian Suppression
    Carolyn Westhoff; Fiscal Year: 2007
    ..This study will have very good power to detect clinically important differences. Results could directly and immediately affect contraceptive practice. ..
  4. Contraceptive Services/Primary Care to Prevent Birth Defects
    Eleanor Schwarz; Fiscal Year: 2007
    ....
  5. Harnessing Health IT to Prevent Medication-Induced Birth Defects
    Eleanor Schwarz; Fiscal Year: 2007
    ..In addition, the Health IT intervention shown to be most effective will be disseminated within the University of Pittsburgh Medical Center, which provides 3 million outpatient visits each year...
  6. Demography Training at Princeton
    James Trussell; Fiscal Year: 2007
    ....
  7. Training in Epidemiology and Clinical Trials (TECT)
    David Grimes; Fiscal Year: 2007
    ....
  8. Clinical Research in Human Fertility
    Joseph Stanford; Fiscal Year: 2005
    ..Standford to develop his skills and gain the expertise needed to accomplish his goals. ..
  9. RCT of a Novel Oral Contraceptive Initiation Method
    Carolyn Westhoff; Fiscal Year: 2004
    ..We will also assess dual method use for STD prevention in the study to adoption of and adherence to oral contraceptives. We will also assess dual method use for STD prevention in the study population. ..
  10. ESTIMATING EFFICACY OF A MEDICAL INTERVENTION
    James Trussell; Fiscal Year: 2001
    ....