biological dressings

Summary

Summary: Human or animal tissue used as temporary wound coverings.

Top Publications

  1. ncbi Immunological characteristics of amniotic epithelium
    Junko Hori
    Department of Ophthalmology, Nippon Medical School, Sendagi 1 1 5, Bunkyo ku, Tokyo 113 8602, Japan
    Cornea 25:S53-8. 2006
  2. doi Recent advances in dermal wound healing: biomedical device approaches
    Simone C Rizzi
    Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, Queensland 4059, Australia
    Expert Rev Med Devices 7:143-54. 2010
  3. ncbi Novel modification of partial nephrectomy technique using porcine small intestine submucosa
    R Corey O'Connor
    Section of Urology, Department of Surgery, University of Chicago Hospitals, Chicago, Illinois, USA
    Urology 60:906-9. 2002
  4. ncbi Update on tissue-engineered biological dressings
    M Ehrenreich
    Department of Dermatology, New Jersey Medical School, Newark, New Jersey 07079, USA
    Tissue Eng 12:2407-24. 2006
  5. ncbi Porcine skin: friend or foe?
    Tor Chiu
    Department of Surgery, Division of Plastic Reconstructive Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong
    Burns 30:739-41. 2004
  6. ncbi Amniotic membrane transplantation: indications and results
    E H Yildiz
    Department of Ophthalmology, Ankara Education and Research Hospital, Ankara Turkey
    Eur J Ophthalmol 18:685-90. 2008
  7. ncbi Amniotic membrane transplantation for reconstruction of corneal epithelial surface in cases of partial limbal stem cell deficiency
    Virender S Sangwan
    Sudhakar and Sreekanth Ravi Stem Cell Biology Laboratory, L V Prasad Eye Institute, Hyderabad, India
    Indian J Ophthalmol 52:281-5. 2004
  8. doi Healing of a porcine burn wound dressed with human and bovine amniotic membranes
    Mushik Park
    Department of Plastic and Reconstructive Surgery, Dongsan Medical Center, Keimyung University, Daegu, South Korea
    Wound Repair Regen 16:520-8. 2008
  9. pmc Ultrastructural analysis of in vivo expanded corneal epithelium on amniotic membrane
    Hyo Shin Ha
    Department of Ophthalmology, Chung Ang University College of Medicine, Seoul, Korea
    J Korean Med Sci 21:544-9. 2006
  10. doi Topical management of facial burns
    Jorge Leon-Villapalos
    Shriners Burns Hospital for Children, 815 Market Street, Galveston, TX 77550, USA
    Burns 34:903-11. 2008

Research Grants

  1. Mesenchymal Stem Cells To Mitigate and Treat Cutaneous Injury Following Radiation
    William H McBride; Fiscal Year: 2010
  2. STRUCTURES.
    CHARLES RODGERS; Fiscal Year: 1999
  3. Novel keratinocyte-based therapy for chronic wounds
    Riley Rees; Fiscal Year: 2002
  4. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Donald Budenz; Fiscal Year: 2004
  5. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Donald Budenz; Fiscal Year: 2007
  6. Heterogeneity of wound macrophages
    JEAN DALEY; Fiscal Year: 2007
  7. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Donald Budenz; Fiscal Year: 2008
  8. Heterogeneity of wound macrophages
    JEAN DALEY; Fiscal Year: 2008

Detail Information

Publications166 found, 100 shown here

  1. ncbi Immunological characteristics of amniotic epithelium
    Junko Hori
    Department of Ophthalmology, Nippon Medical School, Sendagi 1 1 5, Bunkyo ku, Tokyo 113 8602, Japan
    Cornea 25:S53-8. 2006
    ..We therefore suggest that immunogenicity of AE should not be ignored, and use of AM from different donor placentas should be emphasized when repeated AM transplantation is required in patients clinically...
  2. doi Recent advances in dermal wound healing: biomedical device approaches
    Simone C Rizzi
    Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, Queensland 4059, Australia
    Expert Rev Med Devices 7:143-54. 2010
    ..Advanced healing therapies employing biological dressings, skin substitutes, growth factor-based therapies and synthetic acellular matrices, all of which aim to ..
  3. ncbi Novel modification of partial nephrectomy technique using porcine small intestine submucosa
    R Corey O'Connor
    Section of Urology, Department of Surgery, University of Chicago Hospitals, Chicago, Illinois, USA
    Urology 60:906-9. 2002
    ..The most prevalent complications after partial nephrectomy include urinary leakage/fistula and parenchymal bleeding. Porcine SIS has been used in animal models to reconstruct portions of the urinary tract successfully...
  4. ncbi Update on tissue-engineered biological dressings
    M Ehrenreich
    Department of Dermatology, New Jersey Medical School, Newark, New Jersey 07079, USA
    Tissue Eng 12:2407-24. 2006
    Tissue-engineered biological dressings offer promise in the treatment of burns, chronic ulcers, donor site and other surgical wounds, and a variety of blistering and desquamating dermatologic conditions...
  5. ncbi Porcine skin: friend or foe?
    Tor Chiu
    Department of Surgery, Division of Plastic Reconstructive Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong
    Burns 30:739-41. 2004
  6. ncbi Amniotic membrane transplantation: indications and results
    E H Yildiz
    Department of Ophthalmology, Ankara Education and Research Hospital, Ankara Turkey
    Eur J Ophthalmol 18:685-90. 2008
    ..To describe amniotic membrane transplantation indications and results at the authors' institution...
  7. ncbi Amniotic membrane transplantation for reconstruction of corneal epithelial surface in cases of partial limbal stem cell deficiency
    Virender S Sangwan
    Sudhakar and Sreekanth Ravi Stem Cell Biology Laboratory, L V Prasad Eye Institute, Hyderabad, India
    Indian J Ophthalmol 52:281-5. 2004
    ..To assess the efficacy of amniotic membrane for treatment of partial limbal stem cell deficiency (LSCD)...
  8. doi Healing of a porcine burn wound dressed with human and bovine amniotic membranes
    Mushik Park
    Department of Plastic and Reconstructive Surgery, Dongsan Medical Center, Keimyung University, Daegu, South Korea
    Wound Repair Regen 16:520-8. 2008
    ..Our study showed that fresh or acellular bovine AMs provided similar efficacy for wound healing as did the fresh human AMs...
  9. pmc Ultrastructural analysis of in vivo expanded corneal epithelium on amniotic membrane
    Hyo Shin Ha
    Department of Ophthalmology, Chung Ang University College of Medicine, Seoul, Korea
    J Korean Med Sci 21:544-9. 2006
    ..At least 3 months may be needed for the proliferation and differentiation of in vivo cultivated corneal epithelium on AM...
  10. doi Topical management of facial burns
    Jorge Leon-Villapalos
    Shriners Burns Hospital for Children, 815 Market Street, Galveston, TX 77550, USA
    Burns 34:903-11. 2008
    ..Therefore, the classic concept of topical therapy will be expanded and developed within two major stages: acute and rehabilitation. Comparison of the effectiveness of the different treatments and relevant literature will be discussed...
  11. ncbi Amniotic membrane: mother's own remedy for ocular surface disease
    Kenneth R Kenyon
    Cornea 24:639-42. 2005
  12. ncbi Expression of laminin-5 with amniotic membrane transplantation in excimer laser ablated rat corneas
    Jun Haeng Lee
    Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, South Korea
    J Cataract Refract Surg 30:2192-9. 2004
    ..To investigate the expression of laminin-5 during epithelial healing and evaluate its expression in vivo using rat corneas on which amniotic membrane was applied to cover the wound after excimer laser photoablation...
  13. ncbi Amniotic membrane transplantation in severe ocular surface disorders
    M Kaup
    Department of Ophthalmology, RWTH Aachen University, Aachen Germany
    Eur J Ophthalmol 18:691-4. 2008
    ..The authors report complications of corneal surface disorders after successful amniotic membrane transplantation...
  14. ncbi Multilayer amniotic membrane transplantation in the treatment of corneal perforations
    M Teresa Rodríguez-Ares
    Anterior Segment Unit, Department of Ophthalmology, Hospital de Conxo Complejo Hospitalario Universitario de Santiago, Universidad de Santiago de Compostela, Spain
    Cornea 23:577-83. 2004
    ..To determine if multilayer amniotic membrane transplantation (AMT) is useful in the treatment of corneal perforations, and in particular to assess to what extent efficacy is affected by perforation size...
  15. ncbi Radiation processed amniotic membranes in the treatment of non-healing ulcers of different etiologies
    Rita Singh
    Defence Laboratory, Jodhpur, India
    Cell Tissue Bank 5:129-34. 2004
    ..Ulcers with duration of minimum 3 weeks to maximum 12 months were found to heal in 2-6 weeks by the application of amniotic membranes...
  16. pmc Temporary sutureless amniotic membrane patch for acute alkaline burns
    Ahmad Kheirkhah
    Ocular Surface Center, 7000 SW 97th Ave, Ste 213, Miami, FL 33173, USA
    Arch Ophthalmol 126:1059-66. 2008
    ..To evaluate the clinical outcome of a new sutureless approach for a temporary amniotic membrane patch (ProKera; Bio-Tissue, Inc, Miami, Florida) in eyes with acute burns...
  17. ncbi [New developments in skin replacement materials]
    M Przybilski
    BG Unfallklinik Ludwigshafen, Klinik für Hand, Plastische und Rekonstruktive Chirurgie Schwerbrandverletztenzentrum, Plastische und Handchirurgie der Universität Heidelberg, Ludwigshafen przybilski bgu ludwigshafen de
    Chirurg 75:579-87. 2004
    ..This article provides an overview of the currently available products which have already been introduced into clinical routine as well as describing advantages and disadvantages of the individual products and their indications...
  18. ncbi Application of biological dressings from radiosterilized amnios with cobalt 60 and serologic studies on the handling of burns in pediatric patients
    Eligio Ley-Chávez
    Hospital Materno Infantil, ISSEMyM, Toluca, Mexico
    Ann Transplant 8:46-9. 2003
    ..It decreases: 1) the possibility of infection, and therefore reduces the consumption of antibiotic; 2) the use of analgesics; 3) the time of scaring and 4) the number of days of hospitalization...
  19. ncbi Stem cell transplants in ocular surface disorders
    P R Chatterjee
    J Indian Med Assoc 101:457. 2003
  20. ncbi Effect of amniotic membrane after laser-assisted subepithelial keratectomy on epithelial healing: clinical and refractive outcomes
    Hyung Keun Lee
    Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University Seoul, South Korea
    J Cataract Refract Surg 30:334-40. 2004
    ..To evaluate the effect of an amniotic membrane (AM) on reepithelialization time, corneal haze, and postoperative visual and refractive outcomes after laser-assisted subepithelial keratectomy (LASEK) for myopia and myopic astigmatism...
  21. ncbi Amniotic membrane transplantation for ocular surface reconstruction
    Merle Fernandes
    Cornea and Anterior Segment Service, LV Prasad Eye Institute, LV Prasad Marg, Hyderabad, India
    Cornea 24:643-53. 2005
    ..However, further work is needed to elucidate whether it functions merely as a biologic contact lens or whether it has additional benefits...
  22. ncbi Amniotic membrane transplantation in refractory neurotrophic corneal ulcers: a randomized, controlled clinical trial
    Sudarshan Khokhar
    Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, India
    Cornea 24:654-60. 2005
    ..This study was designed to compare and evaluate the efficacy of amniotic membrane transplantation with the conventional management (tarsorrhaphy and bandage contact lens) in eyes with refractory neurotrophic corneal ulcers...
  23. ncbi An investigation into the composition of amniotic membrane used for ocular surface reconstruction
    Leanne J Cooper
    Institute of Environmental and Natural Sciences, Lancaster University, Lancaster LA1 4YQ, United Kingdom
    Cornea 24:722-9. 2005
    ..In this project we characterize, at the ultrastructural level, the extracellular matrix (ECM) components present in AM. We also compare the distribution of ECM components of cellular AM with that of denuded AM...
  24. ncbi Amniotic membrane transplantation for painful bullous keratopathy
    S Srinivas
    Royal Berkshire Hospital, Reading, UK
    Eur J Ophthalmol 17:7-10. 2007
    ..To establish the effectiveness of amniotic membrane transplantation (AMT) in relieving pain and discomfort in patients with painful bullous keratopathy and its role in improving vision in eyes with visual potential...
  25. ncbi Use of amniotic membrane transplantation in the treatment of venous leg ulcers
    Isabelle Mermet
    Universite de Franche Comte, Department of Dermatology, University Hospital and Medical School, Besancon, France
    Wound Repair Regen 15:459-64. 2007
    ..AM transplantation may thus be considered to be an alternative method for treating chronic leg ulcers...
  26. ncbi Microbiological safety and clinical efficacy of radiation sterilized amniotic membranes for treatment of second-degree burns
    Rita Singh
    Defence Laboratory, Defence Research and Development Organization, Jodhpur 342011, India
    Burns 33:505-10. 2007
    ..The application of radiation sterilized amniotic membranes on the burn wound favoured epithelialization. In all the patients, membranes dessicated and separated in 10-14 days time leaving behind an epithelialized surface...
  27. ncbi [Evaluation of the efficiency of amnioplasty in the surgical treatment of severe ocular burn injury]
    E S Miliudin
    Vestn Oftalmol 123:13-7. 2007
    ....
  28. ncbi Amnion in the treatment of pediatric partial-thickness facial burns
    Ludwik K Branski
    Shriners Hospital for Children and University of Texas Medical Branch, 815 Market Street, Galveston, TX 77550, USA
    Burns 34:393-9. 2008
    ....
  29. ncbi Evaluation of visual acuity and color vision in normal human eyes with a sutureless temporary amniotic membrane patch
    Shigeyuki Ijiri
    Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa Prefecture, Japan
    Am J Ophthalmol 144:938-942. 2007
    ..To evaluate how sutureless amniotic membrane patches may affect visual functions in normal human eyes...
  30. ncbi [Treatment of burns by grafting of cultured epithelium]
    Takehiko Nagase
    Department of Plastic and Reconstructive Surgery, St Marianna University School of Medicine, Kanagawa
    Nihon Geka Gakkai Zasshi 106:750-4. 2005
    ..It is expected that cultured epithelial cell grafts will prove to be an effective treatment not only for extensive burns but also to epithelialize small area burn wounds and resurfaced burn scars...
  31. ncbi Xenoderm dressing in the treatment of second degree burns
    Seyed Nejat Hosseini
    Shafieeh hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
    Burns 33:776-81. 2007
    ..Since accurate information about alternative cures is scanty, this study was conducted to assess the outcome of the use of xenoderm biologic dressings as one alternative...
  32. ncbi [Clinical efficacy of jointless therapeutic amnion surfacing of the cornea in its diseases and injury]
    N K Polianskaia
    Vestn Oftalmol 123:21-2. 2007
    ..This option is easy-to-use and enables psychoemotional stress associated with a surgical intervention to be avoided. It may be employed in patients with severe somatic diseases, its clinical effectiveness being retained...
  33. ncbi Amniotic membrane as a biologic pressure patch for treating epithelial ingrowth under a damaged laser in situ keratomileusis flap
    Eun Suk Lee
    Department of Ophthalmology, Yonsei Institute of Vision Research, Seoul, Korea
    J Cataract Refract Surg 32:162-5. 2006
    ..There was no evidence of recurrent epithelial ingrowth after a minimum of 4 months. Use of an amniotic membrane overlay can be an effective adjuvant therapy to secure a LASIK flap when direct suturing would threaten the visual axis...
  34. ncbi [Methods of burn treatment. Part II: Technical aspects]
    N Pallua
    Klinik für Plastische Chirurgie, Hand und Verbrennungschirurgie, Universitatsklinikum Aachen
    Chirurg 77:179-86; quiz 187-8. 2006
    ..Following a debridement conservative treatment of superficial dermal burns involving wound coverage with biosynthetic dressings or nanocristalline silver gauze dressings or use of special disinfecting ointments can be implemented...
  35. ncbi [Use of physiological reparation regulators in glaucoma surgery: a clinicoimmunological study]
    N I Kurysheva
    Vestn Oftalmol 121:21-5. 2005
    ....
  36. ncbi Application of newly developed amniotic membrane ointment for photorefractive keratectomy in rabbits
    Tae Hyun Kim
    Department of Anatomy and Cell Biology, BK21 Program, Dong A University College of Medicine and Medical Science Research Center, Busan, South Korea
    Ophthalmic Res 38:58-61. 2006
    ..Thus, this study could provide basic data on the clinical application of the AMO in the days ahead...
  37. ncbi Preparation, indications and results of human amniotic membrane transplantation for ocular surface disorders
    Jorge L Alio
    VISSUM, Instituto Oftalmologico de Alicante, Research, Development and Innovation Department, Miguel Hernandez University, Alicante, Spain
    Expert Rev Med Devices 2:153-60. 2005
    ..In addition, the beneficial effects of reducing inflammation and neovascularization persist for a long time, if properly cryopreserved...
  38. doi Development and evaluation of silver-impregnated amniotic membrane as an antimicrobial burn dressing
    Rita Singh
    Defence Laboratory, Defence Research and Development Organization, Jodhpur, India
    J Burn Care Res 29:64-72. 2008
    ..The study has demonstrated the ability of silver-impregnated amniotic membrane to combat microbial infection and its ideal physical characteristics for clinical use as a burn wound dressing...
  39. ncbi The amniotic membrane in ophthalmology
    Harminder S Dua
    Division of Ophthalmology and Visual Sciences, University of Nottingham, Nottingham, UK
    Surv Ophthalmol 49:51-77. 2004
    ..Further studies will undoubtedly reveal the true potential of the membrane, its mechanism(s) of action, and the effective use of this tissue in ophthalmology...
  40. ncbi "Amnion Bank"--the use of long term glycerol preserved amniotic membranes in the management of superficial and superficial partial thickness burns
    R Ravishanker
    Department of Plastic Surgery, Army Hospital Research and Referral, Delhi Cantt, 110010, New Delhi, India
    Burns 29:369-74. 2003
    ..This paper shows the excellent results obtained with the use of this extremely economical dressing and emphasizes the importance of establishing such "Amnion Banks" in all hospitals especially in developing countries...
  41. ncbi Symptomatic management of postoperative bullous keratopathy with nonpreserved human amniotic membrane
    Luis F Mejía
    Cornea Service Instituto de Ciencias de la Salud CES Medellín, Colombia
    Cornea 21:342-5. 2002
    ..To report the results of the management of painfully symptomatic postoperative bullous keratopathy (PBK) by performing a nonpreserved human amniotic membrane (NP-AMT) transplantation in nine eyes with poor visual potential...
  42. pmc Amniotic membrane transplantation for reconstruction after excision of large ocular surface neoplasias
    E M Espana
    Department of Ophthalmology, Bascom Palmer Eye Institute, FL, USA
    Br J Ophthalmol 86:640-5. 2002
    ..To evaluate the clinical outcome of patients in whom ocular surface reconstruction was performed using amniotic membrane transplantation (AMT) after the excision of large (>20 mm square) ocular surface neoplasias (OSN)...
  43. ncbi [Use of amniotic membrane transplantation for treating bullous keratopathy]
    Ewa Mrukwa-Kominek
    I Katedry i Kliniki Okulistyki Slaskiej Akademii Medycznej w Katowicach
    Klin Oczna 104:41-6. 2002
    ..The study aimed to evaluate effectiveness of bullous keratopathy treatment using amniotic membrane transplantation, as an alternative method of treatment after cataract surgery...
  44. ncbi What's new in ophthalmic surgery
    Michael A Lemp
    Department of Ophthalmology, Georgetown University, Washington, DC, USA
    J Am Coll Surg 195:361-3. 2002
  45. ncbi Enzymatic debridement of burn wound with collagenase in children with partial-thickness burns
    Coskun Ozcan
    Ege University Faculty of Medicine, Department of Pediatric Surgery, Pediatric Burns Unit, 35100 Bornova, Izmir, Turkey
    Burns 28:791-4. 2002
    ..Thus, CCA should be considered as an initial treatment of choice for removal of eschar in children, having a partial-thickness burn wound without infection...
  46. ncbi Utilisation of glycerolised skin allografts in severe burns
    Ch Dhennin
    Burn Centre, Hopital Trousseau, CHU Tours, 37044 Tours Cedex 01, France
    Burns 28:S21-5. 2002
  47. ncbi The temporary use of allograft for complicated wounds in plastic surgery
    E Moerman
    Department of Plastic and Reconstructive Surgery, 1942 LE Beverwijk, The Netherlands
    Burns 28:S13-15. 2002
    ..We postulate that angiogenic effects of this biological dressing may have contributed to the improved healing conditions and successful secondary wound closure...
  48. ncbi Donor source affects the outcome of ocular surface reconstruction in chemical or thermal burns of the cornea
    Jun Shimazaki
    Department of Ophthalmology, Tokyo Dental College, Chiba, Japan
    Ophthalmology 111:38-44. 2004
    ..To study the association between surgical approach and postoperative results in chemical and thermal burns of the cornea...
  49. ncbi Amniotic membrane implantation as a therapeutic contact lens for the treatment of epithelial disorders
    Oscar Gris
    Department of Ophthalmology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    Cornea 21:22-7. 2002
    ..To evaluate the efficacy and safety of amniotic membrane implantation as a therapeutic contact lens in the treatment of different epithelial defects without stromal ulceration...
  50. ncbi Amniotic membrane in surgery
    M A Ganatra
    Department of Plastic Surgery, Dow Medical College and Civil Hospital, Karachi
    J Pak Med Assoc 53:29-32. 2003
  51. ncbi The use of a collagen sponge/living cell composite material to treat donor sites in burn patients
    Joseph Still
    Physicians Multispecialty Group, 1220 George C Wilson Drive, Augusta, GA 30914, USA
    Burns 29:837-41. 2003
    ..OrCel sites also exhibited reduced scarring. Therefore, treatment of donor site wounds with OrCel is well tolerated, promotes more rapid healing, and results in reduced scarring when compared with conventional therapy with Biobrane-L...
  52. ncbi Human amniotic membrane transplantation: past, present, and future
    Thomas John
    Loyola University at Chicago, Department of Ophthalmology, 2160 South First Avenue, Maywood, IL 60153, USA
    Ophthalmol Clin North Am 16:43-65, vi. 2003
    ..The procurement, complications, and solutions of this delicate procedure are covered with a mention of what is in store for the future...
  53. ncbi Ex vivo expansion of corneal limbal epithelial/stem cells for corneal surface reconstruction
    K Ramaesh
    Princess Alexandra Eye Pavilion, Edinburgh, UK
    Eur J Ophthalmol 13:515-24. 2003
    ..This article is a chronological review of the important steps that brought ex vivo expanded stem cell transplantation in ocular, particularly corneal surface reconstruction...
  54. ncbi Amniotic membrane for repair of exposed hydroxyapatite orbital implant
    Matthew W Lee-Wing
    Department of Ophthalmology, University of Manitoba, Winnipeg, Canada
    Ophthal Plast Reconstr Surg 19:401-2. 2003
    ..5 months, and 5 months after surgery demonstrated closure of the conjunctival defect. The author concludes that amniotic membrane may be useful for the treatment of hydroxyapatite orbital implant exposures...
  55. ncbi Other uses of homologous skin grafts and skin bank bioproducts
    Michele Fimiani
    Department of Dermatologic Sciences, University of Siena, Policlinico Le Scotte, 53100 Siena, Italy
    Clin Dermatol 23:396-402. 2005
    ..Anyway the 3-dimensional model proposed seems to be suitable for the study of the behaviour of peripheral CD 34+ and perhaps also other types of stem cells in 3-dimensional dermal matrix...
  56. pmc Informed consent should be obtained from patients to use products (skin substitutes) and dressings containing biological material
    S Enoch
    Department of Plastic Surgery, University Hospitals of South Manchester, UK
    J Med Ethics 31:2-6. 2005
    Biological products (tissue engineered skin, allograft and xenograft, and biological dressings) are widely used in the treatment of burns, chronic wounds, and other forms of acute injury...
  57. doi Advances in plasma skin regeneration
    K Wade Foster
    Moy Fincher Medical Group, UCLA Medical Plaza, Los Angeles, CA 90024, USA
    J Cosmet Dermatol 7:169-79. 2008
    ..Numerous treatment protocols with variable energy settings allow for individualized treatments and provide the operator with fine control over the degree of injury and length of subsequent recovery time...
  58. doi The use of pericranial flaps for reconstruction and elevation of the lower eyelid
    Vikesh Patel
    Corneoplastic Unit, Queen Victoria Hospital, East Grinstead, UK
    Orbit 29:1-6. 2010
    ..This technique has been employed in patients where standard tarso-conjunctival flaps are not an option and free posterior lamellar grafts cannot be supported due to the lack of viable anterior lamellar flaps...
  59. ncbi Treatment of second degree facial burns with allografts--preliminary results
    Raymund E Horch
    Department of Plastic and Hand Surgery, Medical School, Friedrich Alexander University, Erlangen Nürnberg 12, 91054 Erlangen, Freiburg, Germany
    Burns 31:597-602. 2005
    ..This is in concordance with other reports on scalds. It would be worthwhile to perform more clinical studies with a larger number of patients to further evaluate the effect and function of allogenic skin for facial burns...
  60. ncbi Clinical evaluation of allogeneic cultured dermal substitutes for intractable skin ulcers after tumor resection
    Yoichi Moroi
    Department of Dermatology, Graduate School of Medical Science, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Eur J Dermatol 14:172-6. 2004
    ..Allogeneic CDS functions as an excellent biological dressing, and could dramatically change the treatment of intractable skin ulcers...
  61. pmc The versatility of a glycerol-preserved skin allograft as an adjunctive treatment to free flap reconstruction
    A Z Mat Saad
    Department of Reconstructive Sciences, Hospital Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Indian J Plast Surg 42:94-9. 2009
    ....
  62. ncbi Factors that influence healing in chronic venous ulcers treated with cryopreserved human epidermal cultures
    Amor Khachemoune
    Division of Dermatology, Georgetown University Medical Center, Washington, DC 20007, USA
    Dermatol Surg 28:274-80. 2002
    ..They do not require a biopsy from the patient, an advantage compared to autografts. They seem to act as a biological dressing, stimulating epithelialization from the wound edges and adnexae, probably through growth factor release...
  63. ncbi Microdebrider intracapsular tonsillectomy
    Andrew H Vaughan
    Department of Otolaryngology, Eastern Virginia Medical School, Norfolk, VA 23507, USA
    ORL J Otorhinolaryngol Relat Spec 69:358-63. 2007
    ..This article reviews the published data on microdebrider-assisted partial intracapsular tonsillectomy with a discussion of its advantages, potential limitations and areas of future research...
  64. ncbi Update on dermal substitutes
    Michael Ehrenreich
    Dermatology, New Jersey Medical School, 185 South Orange Avenue, Newark 07103, USA
    Acta Dermatovenerol Croat 14:172-87. 2006
    Tissue-engineered biological dressings offer promise in the treatment of burns, chronic ulcers, donor site and other surgical wounds, and a variety of dermatologic conditions...
  65. ncbi [Biology of epidermal stem cells: impact on medicine]
    Michał Pikuła
    Zakład Immunologii Klinicznej i Transplantologii, Gdanski Uniwersytet Medyczny
    Postepy Hig Med Dosw (Online) 63:449-56. 2009
    ..The possibilities of using epidermal stem cells in medicine are also presented...
  66. ncbi Dermal preservation using the Versajet hydrosurgery system for debridement of paediatric burns
    Tania C S Cubison
    The Northern Regional Burn Centre, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, United Kingdom
    Burns 32:714-20. 2006
    ..both directly during surgical debridement and indirectly by reducing infection and optimising the use of biological dressings. In deep partial thickness burns softer necrotic dermis can be removed with the Versajet sparing the ..
  67. doi Flow cytometric sorting and analysis of human epidermal stem cell candidates
    Michał Pikuła
    Department of Clinical Immunology and Transplantology, Medical University of Gdansk, Debinki 1, 80211 Gdansk, Poland
    Cell Biol Int 34:911-5. 2010
    ..We also performed a flow cytometric analysis of sorted cells using a cell tracer...
  68. ncbi Tissue regeneration in loss of substance on the lower limbs through use of platelet-rich plasma, stem cells from adipose tissue, and hyaluronic acid
    Valerio Cervelli
    Department of Plastic and Reconstructive Surgery, University of Tor Vergata, Rome, Italy
    Adv Skin Wound Care 23:262-72. 2010
    ..It has been demonstrated that mesenchymal stem cells are present in the adipose tissue (thus accelerating the effect of the PRP)...
  69. ncbi Dried irradiated human amniotic membrane as a biological dressing for facial burns--a 7-year case series
    E Bujang-Safawi
    Burn Unit, Reconstructive Sciences Department, Hospital Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia
    Burns 36:876-82. 2010
    ..The observed advantages of human amnion treatment include pain relief, ease of use, prevention of infection and acceleration of wound healing...
  70. ncbi Rearing larvae of Lucilia sericata for chronic ulcer treatment--an improved method
    Hélène Wolff
    Department of Dermatology, Sahlgrenska University Hospital, SE 41345 Goteborg, Sweden
    Acta Derm Venereol 85:126-31. 2005
    ..Adhering to a proposed weekly working schedule makes the rearing procedure effective and reliable...
  71. ncbi Morphofunctional evaluation of the effect of collagen-1-based dressing on skin regeneration after burn trauma in mice of two genetic strains
    E G Kolokolchikova
    N V Sklifosovsky Institute of Urgent Care, Moscow, Russia
    Bull Exp Biol Med 149:154-60. 2010
    ..The possible mechanisms of the stimulatory effect of collagen-based dressing on wound healing are discussed...
  72. doi Microdebrider vs electrocautery: a comparison of tonsillar wound healing histopathology in a canine model
    Kaalan Johnson
    Department of Otolaryngology Head and Neck Surgery, Eastern Virginia Medical School, Norfolk, VA, USA
    Otolaryngol Head Neck Surg 138:486-91. 2008
    ..To evaluate tonsillar wound healing histopathology in a canine model following microdebrider intracapsular and electrocautery tonsillectomy techniques...
  73. doi Treatment of gun-shot defect of the foot with bovine collagen matrix application
    Yusuf Kenan Coban
    Plastic Surgery Department, Sutcu Imam University School of Medicine, Kahramanmaras, Turkey
    Foot (Edinb) 19:222-3. 2009
    ..Lyophilized bovine collagen matrix is one of ideal biological dressings used in wound treatment. We present an example of type 1 bovine collagen (Gelfix, Euroresearch, Inc...
  74. doi In vitro Ad5F35-mediated CTLA4-Ig gene transfer prolongs pig skin xenotransplant survival
    L Ge
    Department of Laboratory Animal Sciences, College of Basic Medicine, Third Military Medical University, Chongqing, China
    Transplant Proc 42:3763-6. 2010
    ..Our results demonstrate that CTLA4Ig gene-modified pig skin is a promising biologic dressing for wound coverage and Ad5F35 an effective viral carrier for delivery...
  75. doi Silica-collagen bionanocomposites as three-dimensional scaffolds for fibroblast immobilization
    Martín F Desimone
    UPMC Université Paris, CNRS, France
    Acta Biomater 6:3998-4004. 2010
    ..environment for fibroblast adhesion, proliferation and biological activity and therefore constitute an original three-dimensional environment for in vitro cell culture and in vivo applications, in particular as biological dressings.
  76. doi Skin bioengineering: preclinical and clinical applications
    L Martinez-Santamaria
    Unidad de Medicina Regenerativa, Departamento de Investigación Básica, División de Biomedicina Epitelial, Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas, Madrid, Spain
    Actas Dermosifiliogr 103:5-11. 2012
    ..This model is suitable for the study of physiologic and pathologic cutaneous processes and the evaluation of treatment strategies for skin diseases, including protocols for gene and cell therapy and tissue engineering...
  77. ncbi [Principles of wound treatment]
    A Bruhin
    Klinik für Viszeralchirurgie, Kantonsspital Luzern
    Ther Umsch 64:473-83. 2007
    ..Increasingly important is it to point out the situation of complexe wounds which should be judgded and treated with the help of a "wound expert"...
  78. ncbi [Bioactive dressings]
    N Grasset
    Service de chirurgie expérimentale et chirurgie pédiatrique, CHUV, 1011 Lausanne
    Rev Med Suisse 6:354-7. 2010
    ..This article provides a general overview of the various product categories and presents their main indications. The principal axes of the biomedical research in this area are also discussed...
  79. ncbi Use of a cell-based interactive wound dressing to enhance healing of excisional wounds in nude mice
    R S Rees
    Section of Plastic Surgery, Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0340, USA
    Wound Repair Regen 9:297-304. 2001
    ..We conclude that a simple interactive wound dressing using either keratinocytes or fibroblasts can enhance the healing of wounds in nude mice...
  80. ncbi The application of deep-frozen and radiation-sterilized human amnion as a biological dressing to prevent prolonged air leakage in thoracic surgery
    Mariusz Zmijewski
    Lung and Thoracic Tumor Department, The Maria Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
    Ann Transplant 10:17-20. 2005
    ..In 80% of the cases, no traces of air leakage was observed. The preliminary results suggest that the application of human amnion grafts may be a safe and effective method for preventing prolonged air leakage after thoracic surgery...
  81. ncbi An allogeneic cultured dermal substitute suitable for treating intractable skin ulcers and large skin defects prior to autologous skin grafting: three case reports
    Toshio Hasegawa
    Department of Dermatology, School of Medicine, Juntendo University, Tokyo, Japan
    J Dermatol 32:715-20. 2005
    ....
  82. doi Postoperative conjunctival inflammation after pterygium surgery with amniotic membrane transplantation versus conjunctival autograft
    Ahmad Kheirkhah
    Farabi Eye Hospital, Eye Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Am J Ophthalmol 152:733-8. 2011
    ..To compare the postoperative conjunctival inflammation around the surgical site after pterygium surgery using either amniotic membrane transplantation (AMT) or free conjunctival autograft...
  83. ncbi Amniotic membrane graft in the surgical management of cryptophthalmos
    Jay M Stewart
    Ophthalmic Plastic and Reconstructive Surgery Service, Department of Ophthalmology, University of California, San Francisco, California 94143 0344, USA
    Ophthal Plast Reconstr Surg 18:378-80. 2002
    ..To describe a case of cryptophthalmos in which an amniotic membrane graft was used in reconstruction of the upper eyelid and fornix...
  84. pmc Bacterial contamination of amniotic membrane
    P J Adds
    Department of Biomedical Sciences, Queen Mary Westfield College, London E1 4NS, UK
    Br J Ophthalmol 85:228-30. 2001
    ..In the light of interest being shown in amniotic membrane grafts for use in ocular surgery, this study aims to identify the bacterial contaminants commonly found on placental membranes from both caesarean and vaginal deliveries...
  85. doi Evaluation of the delivery of mesenchymal stem cells into the root canal space of necrotic immature teeth after clinical regenerative endodontic procedure
    Tyler W Lovelace
    Department of Endodontics, University of Texas Health Science Center, San Antonio, TX, USA
    J Endod 37:133-8. 2011
    ....
  86. ncbi Ocular surface reconstruction: recent advances and future outlook
    Samuel C Yiu
    Ocular Surface Center, Doheny Eye Institute, Los Angeles, CA 90033, USA
    Curr Opin Ophthalmol 18:509-14. 2007
    ..Left untreated, these conditions can progress to vision loss or destruction of the globe itself. This review discusses the most recent and relevant clinical and experimental advances in the treatment options for ocular surface disorders...
  87. ncbi Polytetrafluoroethylene as a spacer graft for the correction of lower eyelid retraction
    Yong Jae Lee
    Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea
    Korean J Ophthalmol 19:247-51. 2005
    ..To evaluate the efficacy of porous expanded polytetrafluoroethylene (e-PTFE, Goretex) containing large pores made with a 21-gauge needle as a graft for the correction of lower lid retraction...
  88. doi Utilizing biologic assimilation of bovine fetal collagen in staged skin grafting
    James Neill
    Department of Pathology, Crossgates River Oaks Hospital, Brandon, MS, USA
    Ann Plast Surg 68:451-6. 2012
    ..BFC may prove to be a valuable material, as the role of acellular dermal matrices in skin grafting becomes better defined...
  89. pmc Antibacterial efficacy of silver-impregnated polyelectrolyte multilayers immobilized on a biological dressing in a murine wound infection model
    Kathleen M Guthrie
    School of Veterinary Medicine, Department of Surgical Sciences, University of Wisconsin, Madison, WI 53706, USA
    Ann Surg 256:371-7. 2012
    ..To investigate the antibacterial effect of augmenting a biological dressing with polymer films containing silver nanoparticles...
  90. doi The role of biologics in pelvic floor surgery
    M Ahmad
    Department of Colorectal Surgery, Queen Elizabeth Hospital, Gateshead, UK
    Colorectal Dis 14:19-23. 2012
    ..We examine the existing literature on the use of biologics in pelvic floor surgery comparing this with literature on synthetic mesh for the key outcomes of infection rates, bowel/sexual function and recurrence...
  91. ncbi Temporary coverage of a forehead defect following tumor resection with a hyaluronic acid biological dressing: a case report
    Vincenzo Vindigni
    Unit of Plastic and Reconstructive Surgery, University of Padova, Padova, Italy
    Ostomy Wound Manage 57:56-60. 2011
    ..Hyaluronic acid biological dressings (HABD) also have been used for the temporary coverage of partial- to full-thickness posttraumatic or ..
  92. doi Application of hyperdry amniotic membrane patches without fibrin glue over the bony surface of mastoid cavities in canal wall down tympanoplasty
    Yuji Kanazawa
    Department of Otolaryngology, University of Toyama, Toyama, Japan
    Acta Otolaryngol 132:1282-7. 2012
    ..Fibrin glue might be an inessential bioadhesive for attachment of hyperdry amniotic membrane (AM) patches in canal wall down (CWD) tympanoplasty...
  93. ncbi Equine pericardium as a biological covering for the treatment of diabetic foot wounds: a prospective study
    Jeffery H Alexander
    Department of Orthopedic Surgery, Rush University Medical Center, Oak Park, IL, USA
    J Am Podiatr Med Assoc 102:352-8. 2012
    ..Collagen-based matrices have been used as wound covers and have been shown to improve and expedite healing. We present our experience with equine pericardium biomatrix for the treatment of neuropathic foot wounds...
  94. doi Perioperative care in functional endoscopic sinus surgery: a survey study
    Rafael Antonio Portela
    Penn State Hershey Medical Center, Division of Otolaryngology, Head and Neck Surgery, Hershey, PA 17033, USA
    Int Forum Allergy Rhinol 2:27-33. 2012
    ..The authors of this survey study did not intend to examine the efficacy of such treatment protocols, but rather to determine and report on the current practice patterns of perioperative FESS care among otolaryngologists...
  95. ncbi A controlled study of amniotic membrane transplantation for acute Pseudomonas keratitis
    Ahmad Kheirkhah
    Farabi Eye Hospital, Eye Research Center, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran
    Can J Ophthalmol 47:305-11. 2012
    ..To evaluate the efficacy of amniotic membrane transplantation (AMT) to improve the outcomes of acute Pseudomonas keratitis as compared with a control group...
  96. doi Mechanical, physical, antioxidant, and antimicrobial properties of gelatin films incorporated with thymol for potential use as nano wound dressing
    Gholamreza Kavoosi
    Inst of Biotechnology, Faculty of Agriculture, Univ of Shiraz, Shiraz, 71441 65186, Iran
    J Food Sci 78:E244-50. 2013
    ..Thus, gelatin films-containing thymol can be used as safe and effective source of natural antioxidant and antimicrobial agents with the purpose of evaluating their potential use as modern nano wound dressing...
  97. ncbi Amnia for intractable skin ulcers with recessive dystrophic epidermolysis bullosa: report of three cases
    Toshio Hasegawa
    Department of Dermatology, Juntendo University School of Medicine, Bunkyo ku, Tokyo, Japan
    J Dermatol 34:328-32. 2007
    ..Amnia could be an effective therapy for intractable skin ulcers in RDEB patients, and should be considered as a re-emerging therapeutic option for the disease...
  98. ncbi Management of severe burn injuries in neonates
    Bing Wei Sun
    Department of Burns and Plastic Surgery, Affiliated Hospital, Jiangsu University, Zhenjiang, Jiangsu Province, PR China
    J Burn Care Rehabil 25:219-23. 2004
    ..Furthermore, a very important issue is also discussed, which is about the prevention of newborn burns in the neonate unit in developing countries...
  99. ncbi [Porcine acellular dermal matrix in the treatment of deep partial-thickness burns in human]
    Xiang sheng Feng
    Department of Surgery, First People s Hospital of Foshan City, Foshan 528000, China
    Di Yi Jun Yi Da Xue Xue Bao 22:844-5, 848. 2002
    ..To investigate the possibility of treating deep partial-thickness burns by closed dressing of the wounds with porcine acellular dermal matrix (ADM) and evaluate the therapeutic effects...
  100. ncbi Preparation of sponge using porcine small intesinal submucosa and their applications as a scaffold and a wound dressing
    Moon Suk Kim
    Nano biomaterials Laboratory, Korea Research Institutes of Chemical Technology, P O Box 107, Yuseong, Daejeon 305 606, Korea
    Adv Exp Med Biol 585:209-22. 2006
  101. ncbi Evaluation of tissue-engineered skin (human skin substitute) and secondary intention healing in the treatment of full thickness wounds after Mohs micrographic or excisional surgery
    Sharon Gohari
    Department of Dermatology, Northwestern University, The Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Dermatol Surg 28:1107-14; discussion 1114. 2002
    ..Human Skin Substitute (HSS) appears to be immunologically inert, and has shown usefulness in the treatment of chronic and acute wounds...

Research Grants8

  1. Mesenchymal Stem Cells To Mitigate and Treat Cutaneous Injury Following Radiation
    William H McBride; Fiscal Year: 2010
    ..To cover wide areas of radiation-induced burns, we will add MSCs on FMBs to natural collagen sheets as a form of biological dressing. ..
  2. STRUCTURES.
    CHARLES RODGERS; Fiscal Year: 1999
    ..Endoscopic insertion, simple in mechanism and short in procedure will lead to good marketability and acceptability in the urological medical community. ..
  3. Novel keratinocyte-based therapy for chronic wounds
    Riley Rees; Fiscal Year: 2002
    ..abstract_text> ..
  4. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Donald Budenz; Fiscal Year: 2004
    ....
  5. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Donald Budenz; Fiscal Year: 2007
    ....
  6. Heterogeneity of wound macrophages
    JEAN DALEY; Fiscal Year: 2007
    ..It is anticipated that findings in this animal model will provide a basis for investigation of wound macrophage phenotypes in human disease, and may identify targets for therapeutic interventions in abnormal healing. ..
  7. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Donald Budenz; Fiscal Year: 2008
    ....
  8. Heterogeneity of wound macrophages
    JEAN DALEY; Fiscal Year: 2008
    ..It is anticipated that findings in this animal model will provide a basis for investigation of wound macrophage phenotypes in human disease, and may identify targets for therapeutic interventions in abnormal healing. ..