erythrocyte indices

Summary

Summary: ERYTHROCYTE size and HEMOGLOBIN content or concentration, usually derived from ERYTHROCYTE COUNT; BLOOD hemoglobin concentration; and HEMATOCRIT. The indices include the mean corpuscular volume (MCV), the mean corpuscular hemoglobin (MCH), and the mean corpuscular hemoglobin concentration (MCHC).

Top Publications

  1. ncbi Importance of RDW value in differential diagnosis of hypochrome anemias
    D Aslan
    Department of Pediatric Hematology, Ihsan Dogramaci Children s Hospital, Hacettepe University, Ankara, Turkey
    Am J Hematol 69:31-3. 2002
  2. pmc Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans
    Ken Sin Lo
    Montreal Heart Institute, 5000 Belanger Street, Montreal, QC, H1T 1C8, Canada
    Hum Genet 129:307-17. 2011
  3. doi Elevated red blood cell distribution width predicts mortality in persons with known stroke
    Chizobam Ani
    Department of Medicine, Charles Drew University of Medicine and Science, USA
    J Neurol Sci 277:103-8. 2009
  4. ncbi Alpha and beta thalassemia
    Herbert L Muncie
    Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Am Fam Physician 80:339-44. 2009
  5. doi Red cell distribution width as a novel prognostic marker in patients undergoing primary angioplasty for acute myocardial infarction
    Huseyin Uyarel
    Department of Cardiology, Balikesir University, School of Medicine, Cagis Campus, Balikesir, Turkey
    Coron Artery Dis 22:138-44. 2011
  6. pmc Red cell distribution width and mortality in older adults: a meta-analysis
    Kushang V Patel
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland 20892 9205, USA
    J Gerontol A Biol Sci Med Sci 65:258-65. 2010
  7. pmc Red blood cell distribution width and the risk of death in middle-aged and older adults
    Kushang V Patel
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, 7201 Wisconsin Ave, Ste 3C309, Bethesda, MD 20814, USA
    Arch Intern Med 169:515-23. 2009
  8. ncbi The cutoff value of serum ferritin for the diagnosis of iron deficiency in community-residing older persons
    Chul Won Choi
    Division of Oncology Hematology, Department of Internal Medicine, Korea University Medical Center, Seoul, South Korea
    Ann Hematol 84:358-61. 2005
  9. doi Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Arch Pathol Lab Med 133:628-32. 2009
  10. ncbi Red cell distribution width in the diagnosis of iron deficiency anemia
    D Viswanath
    Department of Pediatrics, M.S. Ramaiah Medical Teaching Hospital, Bangalore, India
    Indian J Pediatr 68:1117-9. 2001

Detail Information

Publications205 found, 100 shown here

  1. ncbi Importance of RDW value in differential diagnosis of hypochrome anemias
    D Aslan
    Department of Pediatric Hematology, Ihsan Dogramaci Children s Hospital, Hacettepe University, Ankara, Turkey
    Am J Hematol 69:31-3. 2002
    ..These observations could be kept in mind in the differential diagnosis of deltabeta-TT from beta-TT and IDA by determining the red blood cell count, red cell indices, and RDW only...
  2. pmc Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans
    Ken Sin Lo
    Montreal Heart Institute, 5000 Belanger Street, Montreal, QC, H1T 1C8, Canada
    Hum Genet 129:307-17. 2011
    ..Our results show similarities but also differences in the genetic regulation of hematological traits in European- and African-derived populations, and highlight the role of natural selection in shaping these differences...
  3. doi Elevated red blood cell distribution width predicts mortality in persons with known stroke
    Chizobam Ani
    Department of Medicine, Charles Drew University of Medicine and Science, USA
    J Neurol Sci 277:103-8. 2009
    ..We assessed the association of RDW with stroke, and its effect on mortality among persons with stroke...
  4. ncbi Alpha and beta thalassemia
    Herbert L Muncie
    Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Am Fam Physician 80:339-44. 2009
    ..Persons with the thalassemia trait have a normal life expectancy. Persons with beta thalassemia major often die from cardiac complications of iron overload by 30 years of age...
  5. doi Red cell distribution width as a novel prognostic marker in patients undergoing primary angioplasty for acute myocardial infarction
    Huseyin Uyarel
    Department of Cardiology, Balikesir University, School of Medicine, Cagis Campus, Balikesir, Turkey
    Coron Artery Dis 22:138-44. 2011
    ..Red cell distribution width (RDW), a measure of red blood cell size heterogeneity, was evaluated in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI)...
  6. pmc Red cell distribution width and mortality in older adults: a meta-analysis
    Kushang V Patel
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland 20892 9205, USA
    J Gerontol A Biol Sci Med Sci 65:258-65. 2010
    ..Whether RDW is prognostic in more representative community-based populations is unclear...
  7. pmc Red blood cell distribution width and the risk of death in middle-aged and older adults
    Kushang V Patel
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, 7201 Wisconsin Ave, Ste 3C309, Bethesda, MD 20814, USA
    Arch Intern Med 169:515-23. 2009
    ..In patients with symptomatic cardiovascular disease (CVD), RDW is associated with mortality. However, it has not been demonstrated that RDW is a predictor of mortality independent of nutritional deficiencies or in the general population...
  8. ncbi The cutoff value of serum ferritin for the diagnosis of iron deficiency in community-residing older persons
    Chul Won Choi
    Division of Oncology Hematology, Department of Internal Medicine, Korea University Medical Center, Seoul, South Korea
    Ann Hematol 84:358-61. 2005
    ..The value is lower than the previous value established for hospitalized and anemic older adults...
  9. doi Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Arch Pathol Lab Med 133:628-32. 2009
    ..A strong independent association has been recently observed between elevated red blood cell distribution width (RDW) and increased incidence of cardiovascular events...
  10. ncbi Red cell distribution width in the diagnosis of iron deficiency anemia
    D Viswanath
    Department of Pediatrics, M.S. Ramaiah Medical Teaching Hospital, Bangalore, India
    Indian J Pediatr 68:1117-9. 2001
    ..CONCLUSION: In the diagnosis of mild and moderate iron deficiency anemia, RDW had a higher sensitivity than PS. Red cell morphology, Hb, PCV and RDW showed significant improvement after iron-therapy...
  11. pmc Genetic Loci implicated in erythroid differentiation and cell cycle regulation are associated with red blood cell traits
    Keyue Ding
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 87:461-74. 2012
    ..To identify common genetic variants influencing red blood cell (RBC) traits...
  12. doi Red blood cell distribution width as an independent predictor of all-cause mortality in out of hospital cardiac arrest
    Joonghee Kim
    Department of Emergency Medicine, Seoul National University Bundang Hospital, Gumi Ro, Bundang gu, Seongnam si, Gyeonggi do 463 707, Republic of Korea
    Resuscitation 83:1248-52. 2012
    ..Recent studies found that elevated red cell distribution width (RDW) is a strong predictor of mortality in critically ill patients. We investigated the prognostic significance of RDW in out-of-hospital cardiac arrest (OHCA) victims...
  13. doi Usefulness of admission red cell distribution width as a predictor of early mortality in patients with acute pulmonary embolism
    Ali Zorlu
    Department of Cardiology, Cumhuriyet University Medical School, Sivas, Turkey
    Am J Cardiol 109:128-34. 2012
    ..In conclusion, high RDW was associated with worse hemodynamic parameters, and RDW seems to aid in the risk stratification of patients with acute PE...
  14. doi Prognostic implication of macrocytosis on adverse outcomes after coronary intervention
    Masahiro Myojo
    Department of Cardiovascular Medicine, The University of Tokyo, Graduate School of Medicine, Tokyo 113 8655, Japan
    Atherosclerosis 221:148-53. 2012
    ..The aim of this study was to perform prognostic risk stratification of patients after PCI based on the presence or absence of macrocytosis...
  15. pmc Hematologic differences between African-Americans and whites: the roles of iron deficiency and alpha-thalassemia on hemoglobin levels and mean corpuscular volume
    Ernest Beutler
    The Scripps Research Institute, Department of Molecular and Experimental Medicine, 10550 North Torrey Pines Rd, La Jolla, CA 92037, USA
    Blood 106:740-5. 2005
    ..1% and 2.77% and to 4.29% and 3.6%, respectively. Physicians need to take into account that the same reference standards for hemoglobin, hematocrit, MCV, and TS and the white blood cell count do not apply to all ethnic groups...
  16. ncbi The diagnostic criteria for iron deficiency in infants should be reevaluated
    Magnus Domellöf
    Department of Clinical Sciences, Pediatrics, Umea University, Sweden
    J Nutr 132:3680-6. 2002
    ..Hb, MCV and ZPP at 6 mo as well as growth variables predicted the Hb response at 6-9 mo, but ferritin and TfR at 6 mo did not. We conclude that there is need for a reevaluation of the definitions of ID and IDA in infants...
  17. doi Relation between red cell distribution width with echocardiographic parameters in patients with acute heart failure
    Jaewon Oh
    Cardiology Division, Yonsei Cardiovascular Center and Cardiovascular Research Institute, Seoul, Korea
    J Card Fail 15:517-22. 2009
    ..However, the relation between RDW and echocardiographic parameters in acute heart failure (AHF) has not been studied...
  18. doi Evaluation of the diagnostic reliability of different RBC indices and formulas in the differentiation of the beta-thalassaemia minor from iron deficiency in Palestinian population
    M Sirdah
    Biology Department, Al Azhar University, Gaza, Palestine
    Int J Lab Hematol 30:324-330. 2008
    ....
  19. ncbi Validity of carbohydrate-deficient transferrin (%CDT), gamma-glutamyltransferase (gamma-GT) and mean corpuscular erythrocyte volume (MCV) as biomarkers for chronic alcohol abuse: a study in patients with alcohol dependence and liver disorders of non-alcoh
    B Hock
    Psychiatric Clinic of Ludwig Maximilian University, Munich, Germany
    Addiction 100:1477-86. 2005
    ....
  20. ncbi Preparation and in vitro evaluation of carrier erythrocytes for RES-targeted delivery of interferon-alpha 2b
    M Hamidi
    Department of Pharmaceutics, Faculty of Pharmacy, Shiraz University of Medical Sciences, P O Box 71345 1583, Shiraz, Iran
    Int J Pharm 341:125-33. 2007
    ..All the tested in vitro characteristics showed significant, sometimes notable changes upon drug loading procedure, both with and without the drug...
  21. pmc Relationship between alcohol drinking and aspartate aminotransferase:alanine aminotransferase (AST:ALT) ratio, mean corpuscular volume (MCV), gamma-glutamyl transpeptidase (GGT), and apolipoprotein A1 and B in the U.S. population
    Suthat Liangpunsakul
    Division of Gastroenterology and Hepatology, Department of Medicine, and Clarian Digestive Disease Center, Indiana University School of Medicine, and Roudebush Veterans Administration Medical Center, Indianapolis, Indiana 46202 5124, USA
    J Stud Alcohol Drugs 71:249-52. 2010
    ..We examined the relationship between alcohol drinking and the levels of these markers in a national population-based study composed primarily of lighter drinkers...
  22. ncbi Erythrocyte mean corpuscular volume as a surrogate marker for 6-thioguanine nucleotide concentration monitoring in patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine
    Carlton W Thomas
    Division of Gastroenterology and Hepatology, Division of Clinical Pharmacology, and Section of Biostatistics, Mayo Clinic, Rochester, MN 55905, U S A
    Inflamm Bowel Dis 9:237-45. 2003
    ..Measurement of mean corpuscular volume is a simple and inexpensive alternative to measurement of 6-thioguanine nucleotide concentrations in patients treated with azathioprine or 6-mercaptopurine...
  23. doi Usefulness of red cell distribution width as a prognostic marker in pulmonary hypertension
    Chetan V Hampole
    Section of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois, USA
    Am J Cardiol 104:868-72. 2009
    ..39 for NT-pro-BNP). Adding NT-pro-BNP to RDW did not improve the prediction of mortality. In conclusion, RDW is independently associated with death in patients with PH and performs better as a prognostic indicator than NT-pro-BNP...
  24. ncbi Elevated plasma levels of B-type natriuretic Peptide but not C-reactive protein are associated with higher red cell distribution width in patients with coronary artery disease
    Hidekatsu Fukuta
    Department of Cardio Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
    Int Heart J 50:301-12. 2009
    ..001). In conclusion, elevated BNP levels are independently associated with higher RDW in patients with CAD. Neurohumoral activation may be a mechanistic link between increased RDW and adverse clinical outcomes in this population...
  25. ncbi Subcutaneous administration of darbepoetin alfa effectively maintains hemoglobin concentrations at extended dose intervals in peritoneal dialysis patients
    Yu Wei Fang
    Division of Nephrology, Department of Internal Medicine, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan
    Perit Dial Int 29:199-203. 2009
    ..The purpose of this single-center single-arm study was to determine whether darbepoetin alfa, when administered at extended dose intervals, is as effective as rHuEPO for the treatment of renal anemia in patients on peritoneal dialysis...
  26. ncbi Iron status at 1 and 6 years versus developmental scores at 6 years in a well-nourished affluent population
    B S Gunnarsson
    Unit for Nutrition Research, Landspitali University Hospital and Department of Food Science and Nutrition, University of Iceland, IS 101, Reykjavik, Iceland
    Acta Paediatr 96:391-5. 2007
    ..To examine the association between iron status at 1 and 6 years with development at 6 years...
  27. ncbi Hypochromic red blood cells in low-risk myelodysplastic syndromes: effects of treatment with hemopoietic growth factors
    Therese Ljung
    Department of Medicine, Division of Hematology, Karolinska Institutet at Huddinge University Hospital, Stockholm, Sweden
    Haematologica 89:1446-53. 2004
    ..The present study was designed to assess whether functional iron deficiency may develop in MDS patients receiving these treatments...
  28. ncbi Treatment of iron deficiency anemia with intravenous iron preparations
    Saadet Akarsu
    Department of Pediatrics, Medical Faculty of Firat University, Elazig, Turkey
    Acta Haematol 116:51-7. 2006
    ..We aimed to determine the effects of intravenous iron therapy on blood parameters in pediatric patients who do not tolerate oral iron therapy for any reason...
  29. ncbi Gastrointestinal causes of refractory iron deficiency anemia in patients without gastrointestinal symptoms
    B Annibale
    Digestive and Liver Disease Unit, II Clinica Medica, Policlinico Umberto I, Universita La Sapienza, Viale del Policlinico 155, 00161 Rome, Italy
    Am J Med 111:439-45. 2001
    ..CONCLUSION: Gastrointestinal diseases that do not usually cause bleeding are frequently associated with iron deficiency anemia in patients without gastrointestinal symptom or other potential causes of gastrointestinal bleeding...
  30. ncbi Can patient characteristics predict the outcome of endoscopic evaluation of iron deficiency anemia: a multiple logistic regression analysis
    Gabriele Capurso
    Digestive and Liver Disease Unit, 2nd School of Medicine, Department of Public Health Science University La Sapienza, Rome, Italy
    Gastrointest Endosc 59:766-71. 2004
    ..The purpose of this study was to identify clinical and biochemical variables that predict the outcome of upper/lower endoscopy in outpatients with iron deficiency anemia and to determine which endoscopic procedure should be performed first...
  31. ncbi The Advia 120 red blood cells and reticulocyte indices are useful in diagnosis of iron-deficiency anemia
    Sanna Kotisaari
    Department of Clinical Chemistry and Hematology, Kuopio University Hospital, Finland
    Eur J Haematol 68:150-6. 2002
    ..Nevertheless, the advanced RBC and reticulocyte indices may prove to be useful tools in the evaluation of iron status and diagnosis of iron-deficiency anemia...
  32. ncbi Association of erythrocyte indices with glycated haemoglobin in pre-menopausal women
    M Koga
    Department of Internal Medicine, Kinki Central Hospital, Itami, Japan
    Diabet Med 24:843-7. 2007
    Although HbA(1c) is known to be affected by the lifespan of erythrocytes, any association of erythrocyte indices with HbA(1c) in subjects without anaemia is poorly understood...
  33. ncbi Predictors of endoscopic and laboratory evaluation of iron deficiency anemia in hospitalized patients
    George N Ioannou
    Department of Medicine and Division of Gastroenterology, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
    South Med J 100:976-84. 2007
    ..Many hospitalized anemic patients do not undergo appropriate evaluation. We hypothesized that specific clinical variables were likely to be important in triggering evaluation for iron deficiency anemia...
  34. pmc Opportunistic screening for iron-deficiency in 6-36 month old children presenting to the Paediatric Emergency Department
    Martin V Pusic
    Dept of Pediatrics, University of B C, Vancouver, BC, Canada
    BMC Pediatr 5:42. 2005
    ..This study aims to determine the prevalence of a low Mean Cell Volume (MCV) in children having a CBC performed during a PED visit and whether physicians acted upon the abnormal value...
  35. ncbi Does the mean corpuscular volume help physicians evaluate hospitalized patients with anemia?
    S J Seward
    Department of Medicine, New England Deaconess Hospital, Boston, Massachusetts
    J Gen Intern Med 5:187-91. 1990
    ..In this study the MCV did not provide sufficient diagnostic accuracy to be a useful criterion for the selection of more definitive tests in the evaluation of anemia in hospitalized patients...
  36. ncbi Erythrocyte indices for discriminating thalassaemic and non-thalassaemic microcytosis in Indians
    J Kotwal
    Department of Haematology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Natl Med J India 12:266-7. 1999
    ..CONCLUSION: In countries with a high prevalence of iron deficiency, cut-off values for red cell indices should be recalculated using ROC curves...
  37. pmc Detecting iron deficiency in anemic patients with concomitant medical problems
    A M Kis
    University of Wisconsin Department of Medicine, Department of Veterans Affairs Geriatric Research, Education, and Clinical Center, Madison, USA
    J Gen Intern Med 13:455-61. 1998
    ..This is higher than the ferritin level of < or =50 microg/L cited in standard textbooks as evidence of iron deficiency in patients with inflammation, infection, or malignancy...
  38. ncbi Mature erythrocyte indices: new markers of iron availability
    Christophe Bovy
    Haematologica 90:549-51. 2005
    This study was aimed at evaluating mature erythrocyte indices as new markers of iron status...
  39. doi Red cell distribution width (RDW) in the diagnosis of iron deficiency with microcytic hypochromic anemia
    Roosy Aulakh
    Department of Pediatrics, Christian Medical College and Hospital, Ludhiana, Punjab, India
    Indian J Pediatr 76:265-8. 2009
    ..To study the utility of red cell distribution width (RDW) in the diagnosis of iron deficiency among children with microcytic hypochromic anemia...
  40. ncbi Mean red cell volume as a correlate of blood pressure
    D S Sharp
    Honolulu Epidemiology Research Unit, Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Honolulu, Hawaii, USA
    Circulation 93:1677-84. 1996
    ..Epidemiological studies show no relation or higher MCVs. In the present study of elderly men (71 to 93 years of age) of the Honolulu Heart Program, elements of both findings are confirmed...
  41. ncbi Iron deficiency and erythropoiesis: new diagnostic approaches
    Carlo Brugnara
    Children s Hospital Boston, Department of Laboratory Medicine, 300 Longwood Ave, Boston, MA 02115, USA
    Clin Chem 49:1573-8. 2003
    ..The combination of hematologic markers such as reticulocyte hemoglobin content, which decreases with iron deficiency, and R/F ratio may allow for a more precise classification of anemias...
  42. ncbi Immunological and hematological effects observed in B6C3F1 mice exposed to JP-8 jet fuel for 14 days
    D Keil
    National Institute of Occupational Safety and Health, Morgantown, West Virginia, and Department of Health Professions, Medical University of South Carolina, Charleston, South Carolina, USA
    J Toxicol Environ Health A 67:1109-29. 2004
    ....
  43. ncbi Time and temperature dependant changes in red blood cell analytes used for testing recombinant erythropoietin abuse in sports
    Neil Robinson
    Laboratoire Suisse d Analyse du Dopage, Institut Universitaire de Medecine Legale, Lausanne, Switzerland
    Clin Lab 50:317-23. 2004
    ..These recommendations should ideally also be applied to the all the blood controls compulsory for the medical follow up, otherwise unexplainable values could be misinterpreted and could for instance lead to a period of incapacity...
  44. ncbi Iron deficiency in the acute-phase reaction after open aortic surgery
    J V Solis
    Angiology and Vascular Surgery Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Vasc Endovascular Surg 40:392-8. 2006
    ....
  45. ncbi The effect of repeated blood donations on the iron status of Iranian blood donors attending the Iranian blood transfusion organization
    Mahmoud Djalali
    Tehran University of Medical Sciences, Department of Nutrition and Biochemistry, School of Public Health and Institute of Public Health Research Tehran, Iran
    Int J Vitam Nutr Res 76:132-7. 2006
    ..1 g/dL and serum ferritin >/= 35.3 mug/L could donate just once a year. Volunteers who undergo (repeated) blood donation should receive special nutritional care, especially in terms of iron and energy...
  46. ncbi Effect of petroleum products inhalation on some haematological indices of fuel attendants in Calabar metropolis, Nigeria
    A M Okoro
    Department of Physiology, College of Medical Sciences, University of Calabar, Calabar, Cross River State, Nigeria
    Niger J Physiol Sci 21:71-5. 2006
    ..These results indicate that the petroleum fumes cause a reduction in haematological indices which worsens with prolonged exposure...
  47. ncbi Hand strike-induced hemolysis and adaptations in iron metabolism in Basque ball players
    Alfredo Córdova Martínez
    Department of Physiology and Biochemistry, School of Physiotherapy, University of Valladolid, Soria, Spain
    Ann Nutr Metab 50:206-13. 2006
    ..Basque ball players (BBPs) make repeated hand strikes to the ball which involves continuous mechanical trauma...
  48. ncbi Iron status and dietary iron intake of adolescents from a rural community in Sabah, Malaysia
    Leng Huat Foo
    Faculty of Veterinary Science, University of Sydney, Sydney, NSW 2006
    Asia Pac J Clin Nutr 13:48-55. 2004
    ..Priority should therefore be given to the eradication of iron deficiency in adolescents from low-income areas by dietary modification and micronutrient supplementation amongst female adolescents...
  49. ncbi Shortcomings in infant iron deficiency screening methods
    Paul G Biondich
    Children s Health Services Research, Indianapolis, Indiana, USA
    Pediatrics 117:290-4. 2006
    ..Screening for iron deficiency anemia is a well-established practice in pediatrics, but numerous challenges surrounding current recommendations raise questions about the effectiveness of this strategy...
  50. ncbi [Use of alpha-tocopherol in correction of red blood (erythron) system disorders in rats with acute nitrite intoxication]
    E E Miasoedova
    Normal Physiology Department, Ivanovo State Medical Academy, pr Engel sa 8 Ivanovo, 153462 Russia
    Eksp Klin Farmakol 66:35-9. 2003
    ....
  51. ncbi Hematological parameters in tench Tinca tinca after short term exposure to lead
    Syed Lal Shah
    Pakistan Science Foundation, Islamabad
    J Appl Toxicol 26:223-8. 2006
    ....
  52. ncbi The influence of dietary vitamin C and E supplementation on the physiological response of pirarucu, Arapaima gigas, in net culture
    Glauber Cruz de Menezes
    Department of Aquaculture, INPA Amazonian National Research Institute, Av Andre Araujo, 2936, P O Box 478, Manaus, AM 69069 001, Brazil
    Comp Biochem Physiol A Mol Integr Physiol 145:274-9. 2006
    ..gigas immunological status. Red blood cell indices and immune system indicators showed no synergistic effect between the vitamins after supplementing the A. gigas diet with alpha-T+AA...
  53. ncbi Erythropoietic response and hematological parameters in the catfish Clarias albopunctatus exposed to sublethal concentrations of actellic
    B O Mgbenka
    Fisheries and Hydrobiology Research Unit, Department of Zoology, University of Nigeria, Nsukka, Nigeria
    Ecotoxicol Environ Saf 62:436-40. 2005
    ..There was significant leucocytosis in the actellic-exposed fish. The fish exposed to actellic suffered macrocytic anemia. The changes in the hematological parameters were concentration dependent except in leucocyte counts...
  54. ncbi Comparison of hematologic data in world elite junior speed skaters and in non-athletic juniors
    A Mayr
    Laboratory of Clinical Pathology, Hospital of Brunico, Italy, and Faculty of Health Sciences, University Maastricht, The Netherlands
    Int J Sports Med 27:283-8. 2006
    ..In junior athletes we did not find an iron overload as described in some adult athletes...
  55. ncbi Measurement of reticulocyte and red blood cell indices in patients with iron deficiency anemia and beta-thalassemia minor
    José F A Noronha
    Department of Clinical Pathology, School of Medical Sciences, State University of Campinas, Sao Paulo, Brazil
    Clin Chem Lab Med 43:195-7. 2005
    ....
  56. ncbi Blood viscosity and its relationship to iron deficiency, symptoms, and exercise capacity in adults with cyanotic congenital heart disease
    Craig S Broberg
    Adult Congenital Heart Centre, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College School of Medicine, London, England
    J Am Coll Cardiol 48:356-65. 2006
    ..This study sought to determine the relationship between blood viscosity and iron deficiency and their impact on symptoms and exercise function in adults with cyanotic congenital heart disease...
  57. ncbi Allopurinol prevents erythrocyte deformability impairing but not the hematological alterations after limb ischemia-reperfusion in rats
    Norbert Nemeth
    Department of Operative Techniques and Surgical Research, Medical and Health Science Center, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
    J Invest Surg 19:47-56. 2006
    ..In summary, short-term ischemia and reperfusion induced lower red blood cell deformability in the early postoperative period, which could be prevented by allopurinol pretreatment...
  58. ncbi An algorithm using reticulocyte hemoglobin content (CHr) measurement in screening adolescents for iron deficiency
    Nava Stoffman
    Division of Adolescent Young Adult Medicine, Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Adolesc Health 36:529. 2005
    ....
  59. ncbi Analysis of red cell parameters on the Sysmex XE 2100 and ADVIA 120 in iron deficiency and in uraemic chronic disease
    O David
    Department of Clinical Pathology, Regina Margherita S Anna Hospital, Turin, Italy
    Scand J Clin Lab Invest 66:113-20. 2006
    ..The aim of this study was to evaluate the extent to which the red cell parameters, RBC-Y and RET-Y, provided by Sysmex XE 2100, correlate with HYPO and CHr...
  60. ncbi The relationship between haematological indices, serum gamma-glutamyl transferase and glutamate dehydrogenase, visual hepatic damage and worm burden in cattle infected with Fasciola gigantica
    E C Molina
    College of Veterinary Medicine, University of Southern Mindanao, Kabacan, Cotabato 9407, Philippines
    J Helminthol 80:277-9. 2006
    ..Red blood cell counts and packed cell volume were significantly inversely related to worm burden, but animals compensated for reduced numbers of red blood cells by increasing red cell haemoglobin content...
  61. ncbi Effect of polychlorinated biphenyls (Delor 103) on haematological and enzyme parameters of the rainbow trout Oncorhynchus mykiss
    J Rehulka
    Department of Zoology, Silesian Museum, Tyrsova 1, 746 46 Opava, Czech Republic
    Dis Aquat Organ 62:147-53. 2004
    ..The sodium level fell. The fish injected with Delor 103 showed a relative decrease in the lymphocyte count and a relative increase in the count of neutrophile band forms...
  62. ncbi Initial diagnosis of anemia from sore mouth and improved classification of anemias by MCV and RDW in 30 patients
    Shin Yu Lu
    Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98:679-85. 2004
    ..Improved diagnosis and classification of anemia based on the mean and heterogeneity of red cell size will be discussed...
  63. ncbi Exertional Rhabdomyolysis during a 246-km continuous running race
    Katerina P Skenderi
    Laboratory of Nutrition and Clinical Dietetics, Department of Nutrition and Dietetics, Harokopio University, Athens, Greece
    Med Sci Sports Exerc 38:1054-7. 2006
    ..To evaluate the effect of continuous, moderate-intensity ultra-endurance running exercise on skeletal muscle and hepatic damage, as indicated by serum enzyme activity measured immediately following the race...
  64. ncbi Live high-train low for 24 days increases hemoglobin mass and red cell volume in elite endurance athletes
    Jon Peter Wehrlin
    Swiss Federal Institute of Sports, Section for Elite Sport, 2532 Magglingen, Switzerland
    J Appl Physiol (1985) 100:1938-45. 2006
    ..1,080+/-98 s; P<0.01) from pre- to postaltitude. Living at 2,500 m and training at lower altitudes for 24 days increases Hbmass and RCV. These changes may contribute to enhance performance of elite endurance athletes...
  65. ncbi Development of parameters influencing blood oxygen carrying capacity in the welcome swallow and fairy martin
    Prudence Simmons
    Wildlife Ecology Research Group, School of Biological Sciences, Monash University, Victoria 3800, Australia
    Comp Biochem Physiol A Mol Integr Physiol 143:459-68. 2006
    ..3- to 1.5-fold. Possible reasons for the apparent differences in the timing of O2Cap increase between rapidly and slowly growing altricial species and among MOR species are discussed...
  66. ncbi Specific activities of poetam preparation (superlow-doses of antibodies to erythropoietin) and recombinant erythropoietin
    A M Dygai
    Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences
    Bull Exp Biol Med 142:320-3. 2006
    ..The effect of Recormon manifested immediately after injection, while the effect of Poetam was somewhat delayed, but more lasting (due to activation of host erythropoietin system)...
  67. ncbi The effect of common hematologic abnormalities on the ability of blood models to detect erythropoietin abuse by athletes
    Robin Parisotto
    Department of Physiology, Australian Institute of Sport, PO Box 176, Belconnen ACT 2616, Australia
    Haematologica 88:931-40. 2003
    ..Because hematologic abnormalities can also result in unusual blood profiles, the aim of this study was to document the incidence and magnitude of such abnormalities in an elite athlete population...
  68. ncbi Reduced Ca2+ entry and suicidal death of erythrocytes in PDK1 hypomorphic mice
    Michael Foller
    Department of Physiology, University of Tuebingen, Gmelinstr 5, 72076 Tubingen, Germany
    Pflugers Arch 455:939-49. 2008
    ..The experiments reveal that PDK1 deficiency is associated with decreased Ca2+ entry into erythrocytes and thus with blunted eryptotic effects of oxidative stress, osmotic shock and Cl- removal...
  69. ncbi Serum transferrin receptor in the evaluation of the iron status in elderly hospitalized patients with anemia
    Etienne Joosten
    Division of Geriatric Medicine, Department of Physiopathology, University Hospitals K U Leuven, Belgium
    Am J Hematol 69:1-6. 2002
    ..We conclude that serum ferritin is a more sensitive and specific parameter than the sTfR assay to predict the bone marrow iron status in an elderly anemic population...
  70. ncbi A real-time classification system of thalassemic pathologies based on artificial neural networks
    S R Amendolia
    Dipartimento di Matematica e Fisica, Universita di Sassari, Italy
    Med Decis Making 22:18-26. 2002
    ..On the basis of these results, an automated system that allows real-time support for diagnoses is proposed. The automated system interfaces a hemochromo analyzer to a simple PC...
  71. ncbi Iron-deficient erythropoiesis in neonatal rats
    Suzanne H Dubuque
    Department of Pediatrics, Steele Memorial Children s Research Center, University of Arizona Health Sciences Center, Tucson, AZ 85724 5073, USA
    Biol Neonate 81:51-7. 2002
    ..The neonatal rat is an excellent model of iron-deficient erythropoiesis and will be useful in designing future mechanistic studies examining the interplay between iron and erythropoiesis in the anemic, iron-challenged premature neonate...
  72. ncbi Comparison of iron and hematological indices in Giardia lamblia infection before and after treatment in 102 children in Ahwaz, Iran
    Seyed Mehdi Monajemzadeh
    Department of Pediatrics, Golestan Hospital, Ahwaz Jundishapur University of Medical Sciences, Ahwaz, Iran
    Med Sci Monit 14:CR19-23. 2008
    ..The aim of this study was to evaluate the effects of giardiasis treatment on hematological indices in children in the Khuzestan area by comparing these indices before and after treatment with metronidazole...
  73. ncbi Anemia of chronic disease is the more frequent type of anemia seen in patients with chronic idiopathic neutropenia of adults
    H A Papadaki
    Department of Hematology of the University of Crete School of Medicine, University Hospital of Heraklion, Greece
    Ann Hematol 80:195-200. 2001
    ..These findings further support our previously reported suggestion for the possible existence, in NI-CINA patients, of an unrecognized low-grade chronic inflammatory process that may be involved in the pathogenesis of the disorder...
  74. doi The relationship between normocytic, hypochromic anaemia and iron concentration together with hepatic enzyme activities in cattle infected with Fasciola hepatica
    S Lotfollahzadeh
    Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
    J Helminthol 82:85-8. 2008
    ..The increased activities of serum enzymes indicated chronic hepatic and bile duct injuries associated with chronic infection with F. hepatica...
  75. ncbi Efficacy and safety of intravenously administered iron sucrose with and without adjuvant recombinant human erythropoietin for the treatment of resistant iron-deficiency anemia during pregnancy
    C Breymann
    Department of Obstetrics and Gynecology, the Clinic of Obstetrics, and the Division of Perinatal Physiology, University of Zurich, Switzerland
    Am J Obstet Gynecol 184:662-7. 2001
    ..CONCLUSION: Adjuvant recombinant human erythropoietin safely enhanced the efficacy of iron sucrose in the treatment of gestational iron-deficiency anemia resistant to orally administered iron alone...
  76. doi Iron deficiency anemia, beta-thalassemia minor, and anemia of chronic disease: a morphologic reappraisal
    Alexandra M Harrington
    Department of Pathology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Am J Clin Pathol 129:466-71. 2008
    ....
  77. pmc Iron overload and heart fibrosis in mice deficient for both beta2-microglobulin and Rag1
    M M Santos
    Departments of Immunology, Pathology, and Internal Medicine, University Hospital Utrecht, Utrecht, The Netherlands
    Am J Pathol 157:1883-92. 2000
    ..Mice deficient in ss2m and Rag1 thus offer a new experimental model of iron-related cardiomyopathy...
  78. doi Hematological parameters and anaerobic threshold in Brazilian soccer players throughout a training program
    A S R Silva
    Department of Physical Education, Bioscience Institute, University of Sao Paulo State Unesp, Rio Claro, Sao Paulo, Brazil
    Int J Lab Hematol 30:158-66. 2008
    ..Furthermore, we did not observe any correlation between the anaerobic threshold and the hematological parameters...
  79. doi Restless leg syndrome: iron important
    Margaret A Fitzgerald
    Fitzgerald Health Education Associates, Inc, North Andover, MA, USA
    Nurse Pract 33:7-9. 2008
  80. ncbi [Anaemia, iron index status and acute phase proteins in malaria (Abidjan, Côte d'Ivoire)]
    H Ahiboh
    Departement de Biochimie, Institut Pasteur de Côte d Ivoire, BP 490 Abidjan 01, Cote d Ivoire
    Bull Soc Pathol Exot 101:25-8. 2008
    ..When parasitaemia is low anaemia gets a haemolytic feature. When parasitaemia is high, anaemia gets haemolytic and inflammatory features. Anaemia occurs more often with a good iron index status...
  81. doi Reticulocyte hemoglobin content for the diagnosis of iron deficiency
    Maria Elena Mateos
    Department of Pediatrics, University Hospital Reina Sofia, Cordoba, Spain
    J Pediatr Hematol Oncol 30:539-42. 2008
    ..Therefore, we conclude that the hematologic parameter CHr constitutes a valuable screening tool for the identification of ID with or without anemia in childhood...
  82. ncbi Hematological and blood viscosity changes in tail-suspended rats
    David K Saunders
    Department of Biological Sciences, Emporia State University, KS 66801, USA
    Aviat Space Environ Med 73:647-53. 2002
    ..Rat tail-suspension models mimic the fluid shifts and hematological changes associated with microgravity exposure...
  83. ncbi Regulation of iron absorption in Hfe mutant mice
    Richard S Ajioka
    Division of Hematology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City 84132, USA
    Blood 100:1465-9. 2002
    ..Our data indicate that Hfe mutant mice retain the ability to regulate iron absorption. Mouse hemachromatosis protein (Hfe) plays a minor role in down-regulation but does not influence the up-regulation of iron absorption...
  84. ncbi Effects of zinc deficiency and supplementation on some hematologic parameters of rats performing acute swimming exercise
    Abdulkerim Kasim Baltaci
    Department of Physiology, Meram Medical School of Selcuk University, Konya, Turkey
    Acta Physiol Hung 90:125-32. 2003
    ..05). Our findings suggest that zinc deficiency effects the hematologic parameters mentioned negatively whereas zinc supplementation has a positive influence...
  85. ncbi Low dose intravenous ascorbic acid for erythropoietin-hyporesponsive anemia in diabetic hemodialysis patients with iron overload
    Chun Liang Lin
    Department of Nephrology, Chang Gung Memorial Hospital, Chia Yi, Taiwan
    Ren Fail 25:445-53. 2003
    ..Therefore, the aim of this study focusing on diabetic ESRD patients was to analyze the potential effect of low dose IVAA on improvement of anemia and erythropoiesis-related parameters when compared with control period...
  86. ncbi Erythrocyte protoporphyrin or hemoglobin: which is a better screening test for iron deficiency in children and women?
    Zuguo Mei
    Division of Nutrition and Physical Activity, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Am J Clin Nutr 77:1229-33. 2003
    ..Hemoglobin and erythrocyte protoporphyrin (EP) tests are commonly used to screen for iron deficiency. However, little research has been done to systematically evaluate the sensitivity and specificity of these 2 tests...
  87. ncbi Incidence of high erythrocyte count in infants and young children with iron deficiency anemia: re-evaluation of an old parameter
    Deniz Aslan
    Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey
    J Pediatr Hematol Oncol 25:303-6. 2003
    ..0 x 106/microL) in infants and young children with iron deficiency anemia and to document the differences in hematologic parameters at diagnosis and during iron therapy in IDA patients with and without a high erythrocyte count...
  88. ncbi Long-term hematological effects in Special Forces trainees
    Izhak Kehat
    Israel Naval Medical Institute, Israel Defense Forces Medical Corps, Haifa 31 080, Israel
    Mil Med 168:116-9. 2003
    ..Because these lower values were not seen in an otherwise identical group of submarine trainees, they could be attributed to the endurance training...
  89. ncbi Diagnosing iron deficiency in cyanotic heart disease
    Cemile Banu Onur
    Dr Sami Ulus Children Hospital, Ankara, Turkey
    Indian J Pediatr 70:29-31. 2003
    ..To determine the incidence of iron deficiency in children with CCHD by noninvasive, inexpensive and easy laboratory methods...
  90. ncbi Effect of oral tetracycline on iron absorption from iron(III)-hydroxide polymaltose complex in patients with iron deficiency anemia / a single-centre randomized controlled isotope study
    Maria A Potgieter
    Farmovs Parexel, Bloemfontein, South Africa
    Arzneimittelforschung 57:376-84. 2007
    ..No differences between the two treatment groups with regard to the erythrocyte iron uptake were found, and thus IPC can be used with tetracycline, if necessary...
  91. ncbi Longitudinal study of diet and iron deficiency anaemia in infants during the first two years of life
    Anne Louise M Heath
    Department of Human Nutrition, University of Otago, Dunedin, New Zealand
    Asia Pac J Clin Nutr 11:251-7. 2002
    ..The iron intakes of this group of Caucasian infants and young children appeared inadequate. However, their rate of iron deficiency anaemia was lower than has been reported in previous New Zealand studies...
  92. ncbi Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers
    H V L N Swamy
    Department of Animal and Poultry Science, University of Guelph, ON, Canada
    Poult Sci 81:966-75. 2002
    ..It was concluded that broiler chickens may be susceptible to Fusarium mycotoxicoses when naturally contaminated grains are fed containing a combination of mycotoxins...
  93. ncbi Hematological effects of four ethylene glycol monoalkyl ethers in short-term repeated exposure in rats
    Andrzej Starek
    Department of Biochemical Toxicology, Medical College, Jagiellonian University, Krakow, Poland
    Arch Toxicol 82:125-36. 2008
    ..On the contrary, tolerance to IPE- and BE-induced hemolysis in rats exposed to these compounds was prompted...
  94. ncbi Hematologic values for tule elk (Cervus elaphus nannodes)
    Susan E Shideler
    Institute of Toxicology and Environmental Health, School of Veterinary Medicine, University of California, Davis, California 95616, USA
    J Wildl Dis 38:589-97. 2002
    ..Differences between capture groups were assessed. Greatest differences were detected between yearling bulls and cows in December 1998 which may be a reflection of age and reproductive status...
  95. ncbi Blood parameters and metabolites in the teleost fish Colossoma macropomum exposed to sulfide or hypoxia
    E G Affonso
    Department of Aquaculture, National Institute of Amazonian Research, Av Andre Araujo, 2936, P O Box 478, 69083 000 Manaus, AM, Brazil
    Comp Biochem Physiol C Toxicol Pharmacol 133:375-82. 2002
    ..The high sulfide tolerance in tambaqui is associated with its high tolerance to hypoxia...
  96. ncbi Tolerance and efficacy of intravenous iron saccharate for iron deficiency anemia in children and adolescents receiving long-term parenteral nutrition
    L Michaud
    Division of Gastroenterology, Hepatology and Nutrition, Faculty of Medicine and Children s Hospital, Lille University, Lille, France
    Clin Nutr 21:403-7. 2002
    ....
  97. ncbi Changes of hematological parameters in Prochilodus lineatus (Pisces, Prochilodontidae) exposed to sublethal concentration of cypermethrin
    M J Parma
    Instituto Nacional de Limnología INALI CONICET UNL, Jose Macia 1933, 3016 Santo Tome, Santa Fe, Argentina
    J Environ Biol 28:147-9. 2007
    ..These reports indicate that hematological parameters, may be useful as a diagnostic test for cypermethrin exposure in aquatic organisms...
  98. ncbi Klinefelter's syndrome presenting with leg ulcers
    Helena Martinez De Morentin
    Department of Dermatology, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, Tel Aviv 64239 Israel
    Skinmed 3:274-8. 2004
    ..The patient was treated with IM testosterone once monthly for 1 year, which resulted in a reduction in the diameter and depth of the leg ulcers (Figure 3). Blood tests were not performed for follow-up of the immune state...
  99. pmc Parameters of disease progression in long-term experimental feline retrovirus (feline immunodeficiency virus and feline leukemia virus) infections: hematology, clinical chemistry, and lymphocyte subsets
    R Hofmann-Lehmann
    Department of Internal Veterinary Medicine, Faculty of Veterinary Medicine, University of Zurich, Switzerland
    Clin Diagn Lab Immunol 4:33-42. 1997
    ..The many parallels between laboratory parameters in FIV and HIV infection further support the importance of FIV as a model for HIV...
  100. ncbi Relationship between alpha-fetoprotein and fetal erythropoiesis
    J L Bartha
    Department of Obstetrics and Gynecology, University Hospital of Puerto Real, University of Cadiz, Spain
    J Reprod Med 44:689-97. 1999
    ..To evaluate the relationship of fetal erythropoiesis to both maternal and fetal serum alpha-fetoprotein (AFP) levels...
  101. ncbi Effectiveness of intermittent iron treatment of two- to six-year-old Jordanian children with iron-deficiency anemia
    Ahmad M Faqih
    Department of Nutrition and Food Science, Faculty of Agriculture, University of Jordan, Amman, Jordan
    Food Nutr Bull 27:220-7. 2006
    ..Such a study has not been carried out in 2- to-6-year-old Jordanian children diagnosed with iron deficiency anemia in a clinical setting...

Research Grants117 found, 100 shown here

  1. Painless Microsampling System for Total Hemoglobin and Hematocrit Monitoring
    Brian Sullivan; Fiscal Year: 2007
    ..Its ease of use will also make it attractive for nursing homes, home health care, and other out-patient point-of-care applications. ..
  2. RBC Ion Transporters as Hemoglobinopathy Risk Modifiers
    Seth Alper; Fiscal Year: 2007
    ..The proposed experiments will increase understanding of sickle cell disease and thalassemia by providing mouse models for genetic tests of new drug therapies under development for near-term clinical testing. ..
  3. RBC Ion Transporters as Hemoglobinopathy Risk Modifiers
    Seth Alper; Fiscal Year: 2007
    ..The proposed experiments will increase understanding of sickle cell disease and thalassemia by providing mouse models for genetic tests of new drug therapies under development for near-term clinical testing. ..
  4. RBC Ion Transporters as Hemoglobinopathy Risk Modifiers
    Seth Alper; Fiscal Year: 2009
    ..The proposed experiments will increase understanding of sickle cell disease and thalassemia by providing mouse models for genetic tests of new drug therapies under development for near-term clinical testing. ..
  5. DIETARY PATTERNS AND RISK OF CARDIOVASCULAR DISEASE
    Frank B Hu; Fiscal Year: 2010
    ..In addition, we will analyze relations between dietary, plasma, and erythrocyte indices of fat lipophilicity and major etiological biomarkers of CHD (inflammation, insulin resistance, lipids, and ..
  6. DIETARY PATTERNS AND RISK OF CARDIOVASCULAR DISEASE
    Frank Hu; Fiscal Year: 2009
    ..In addition, we will analyze relations between dietary, plasma, and erythrocyte indices of fat lipophilicity and major etiological biomarkers of CHD (inflammation, insulin resistance, lipids, and ..
  7. Hemolytic Anemia: Models
    LUANNE PETERS; Fiscal Year: 2006
    ..5 isoform in the structure and assembly of the sarcoplasmic reticulum by an in vivo developmental study. ..
  8. Modulators of Nitric Oxide Synthase Activity in Sickle Cell Disease
    Mary E Fabry; Fiscal Year: 2010
    ..These observations may be applicable to patient interventions. ..
  9. ORGANELLE MEMBRANES IN PLATELET STORAGE POOL DISEASE
    LUANNE PETERS; Fiscal Year: 2009
    ..Lung fibrosis typically leads to death in the 4th to 5th decades. This study is designed to identify the underlying genetic causes of HPS, which will provide avenues of research for potential therapies. ..
  10. ORGANELLE MEMBRANES IN PLATELET STORAGE POOL DISEASE
    LUANNE PETERS; Fiscal Year: 2005
    ..abstract_text> ..
  11. CORE--TRANSGENIC MICE
    MARY FABRY; Fiscal Year: 2002
    ....
  12. GENETIC INTERACTIONS IN RED CELL MEMBRANE DISEASE
    LUANNE PETERS; Fiscal Year: 2003
    ....
  13. Adducin and the Membrane Skeleton
    LUANNE PETERS; Fiscal Year: 2007
    ..Follow up studies will include electrocardiology and echocardiology. ..
  14. ORGANELLE MEMBRANES IN PLATELET STORAGE POOL DISEASE
    LUANNE PETERS; Fiscal Year: 2007
    ..Lung fibrosis typically leads to death in the 4th to 5th decades. This study is designed to identify the underlying genetic causes of HPS, which will provide avenues of research for potential therapies. ..
  15. Genetic Identification of Novel Genes Critical in Erythropoiesis
    LUANNE PETERS; Fiscal Year: 2009
    ....
  16. Complex Trait Analysis of Erythropoiesis in Normal Populations
    LUANNE PETERS; Fiscal Year: 2009
    ..Identifying the primary genetic determinants of baseline peripheral blood traits will enhance our understanding of blood formation and provide novel diagnostic and therapeutic targets for hematological and cardiovascular pathologies. ..
  17. Genomic and Proteomic Approaches to Complex Heart, Lung, Blood, & Sleep Disorders
    LUANNE PETERS; Fiscal Year: 2007
    ..Short courses such as these are critical to develop the cadre of highly skilled young clinical investigators and researchers that know how to use the latest tools in solving the genetic underpinnings of these disease. (End of Abstract) ..
  18. Iron Status: A Pathway Analysis in Multiple Ethnicities
    Christine McLaren; Fiscal Year: 2009
    ..Potential study results could be used to identify individuals at risk for iron deficiency and to develop innovative prevention and treatment strategies. ..
  19. Iron Status: A Pathway Analysis in Multiple Ethnicities
    Christine McLaren; Fiscal Year: 2007
    ..Potential study results could be used to identify individuals at risk for iron deficiency and to develop innovative prevention and treatment strategies. ..
  20. Mouse Models for Heart, Lung and Blood Disease
    LUANNE PETERS; Fiscal Year: 2007
    ..New mouse models will be cryo-preserved in order to maintain their availability. Provision are likewise to maintain all JAX PGA resources beyond the PGA program. ..
  21. Complex Trait Analysis of Erythropoiesis in Normal Populations
    LUANNE PETERS; Fiscal Year: 2007
    ..Identifying the primary genetic determinants of baseline peripheral blood traits will enhance our understanding of blood formation and provide novel diagnostic and therapeutic targets for hematological and cardiovascular pathologies. ..
  22. ORGANELLE MEMBRANES IN PLATELET STORAGE POOL DISEASE
    LUANNE PETERS; Fiscal Year: 2000
    ..2 in organelles. Ultimately, this research will identify the genetic defects that cause SPD in humans, a prerequisite to the development of effective gene therapy interventions for their treatment and eventual cure. ..
  23. DETECTION OF HYPOXIA IN SICKLE CELL ANEMIA BY SUSCEPTIBILITY EFFECTS
    MARY FABRY; Fiscal Year: 2000
    ..A goal of these studies is to separate acute, ongoing events from the results of previous episodes of ischemia and fibrosis or expansion of hematopoietic tissue. ..
  24. Timing, Duration and Severity of Infant Iron Deficiency: Developmental Impacts
    Betsy Lozoff; Fiscal Year: 2009
    ....
  25. Timing, Duration and Severity of Infant Iron Deficiency: Developmental Impacts
    Betsy Lozoff; Fiscal Year: 2007
    ....
  26. Taking Community Action Against Pain
    MANNEY REID; Fiscal Year: 2007
    ..g., senior centers). ..
  27. Timing, Duration and Severity of Infant Iron Deficiency: Developmental Impacts
    Betsy Lozoff; Fiscal Year: 2010
    ....
  28. Maternal flu infection and brain development in primates
    Christopher L Coe; Fiscal Year: 2010
    ....
  29. Biotin Status in Pregnancy
    Donald M Mock; Fiscal Year: 2010
    ..Given the expense of such trials, the smaller study proposed here is an essential prerequisite in a line of research with substantial healthcare implications. ..
  30. Timing, Duration and Severity of Infant Iron Deficiency: Developmental Impacts
    Betsy Lozoff; Fiscal Year: 2009
    ....
  31. Timing, Duration and Severity of Infant Iron Deficiency: Developmental Impacts
    Betsy Lozoff; Fiscal Year: 2010
    ....
  32. Gestational Stress and Impaired Iron Homeostasis in the Young Infant
    Christopher L Coe; Fiscal Year: 2010
    ..The findings may reveal deficits that are amenable to prevention and treatment. ..
  33. Maternal flu infection and brain development in primates
    Christopher L Coe; Fiscal Year: 2010
    ..Primate studies of prenatal flu infection are critical at this juncture to bridge the findings in rodent models and concerns raised by retrospective analyses of human samples. ..
  34. Neuromaturational Delays in Iron Deficient Anemic Infants
    Betsy Lozoff; Fiscal Year: 2009
    ..Long-term ill effects continuing into adolescence, despite iron therapy in infancy, could therefore have major public health implications. ..
  35. Hemochromatosis -- Epidemiology and Molecular Mechanisms
    Ernest Beutler; Fiscal Year: 2006
    ..The projected studies should improve our understanding of control of iron metabolism and make possible detection of those cases of hemochromatosis who are likely to become clinically affected. ..
  36. A Mouse Model of Gaucher Disease
    Ernest Beutler; Fiscal Year: 2005
    ..In particular, electron microscopy and light microscopy will be used to attempt to demonstrate the development of Gaucher cells in the chimeric mice. ..
  37. HEMOCHROMATOSIS--EPIDEMIOLOGY AND MOLECULAR MECHANISMS
    Ernest Beutler; Fiscal Year: 2002
    ..This will be done by using immunoprecipitating HLA-H containing complexes, determining HLA-H Fc receptor signaling properties and measuring the binding of peptides and other small molecules by HLA-H. ..
  38. VIRUS PHOTOINACTIVATION--DIMETHYLMETHYLENE BLUE IN RBC
    Stephen Wagner; Fiscal Year: 2004
    ..abstract_text> ..
  39. INDICES OF BIOTIN NUTRITION
    Donald Mock; Fiscal Year: 2001
    ..4) Whether biotin deficiency of similar severity to that observed either early or late in human gestation causes increased rates of fetal malformation in the mouse. 5) The enzyme(s) responsible for biotin beta-oxidation. ..
  40. Neuromaturational Delays in Iron Deficient Anemic Infants
    Betsy Lozoff; Fiscal Year: 2007
    ..Long-term ill effects continuing into adolescence, despite iron therapy in infancy, could therefore have major public health implications. ..
  41. Implementing a Cognitive/Exercise Therapy for Back Pain in The Community Setting
    MANNEY REID; Fiscal Year: 2007
    ..Elaine Wethington), and geriatric physical therapy and instructional development and evaluation (Dr. Katherine Beissner), and are highly qualified to conduct the planned research. ..