differential diagnosis

Summary

Summary: Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.

Top Publications

  1. ncbi A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis
    Vanda A Lennon
    Department of Neurology, Mayo Clinic Rochester, Rochester, MN 55905, USA
    Lancet 364:2106-12. 2004
  2. ncbi Revised diagnostic criteria for neuromyelitis optica
    D M Wingerchuk
    Department of Neurology, Mayo Clinic College of Medicine, Scottsdale, AZ 85259, USA
    Neurology 66:1485-9. 2006
  3. ncbi Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease
    G M McKhann
    Department of Neurology, Zanvyl Krieger Mind Brain Institute, Johns Hopkins University School of Medicine, 338 Krieger Hall, 3400 N Charles St, Baltimore, MD 21218 2685, USA
    Arch Neurol 58:1803-9. 2001
  4. ncbi Real-time ultrasound elastography in the differential diagnosis of benign and malignant thyroid nodules
    Yurong Hong
    Second Affiliated Hospital, Zhejiang University College of Medicine, Zhejiang, China
    J Ultrasound Med 28:861-7. 2009
  5. doi Differential diagnosis of hepatic tumors: value of contrast-enhanced harmonic sonography using the newly developed contrast agent, Sonazoid
    Kinuyo Hatanaka
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine, Osaka Sayama, Japan
    Intervirology 51:61-9. 2008
  6. pmc Differential diagnosis of suspected multiple sclerosis: a consensus approach
    D H Miller
    Department of Inflammation, Institute of Neurology, NMR Research Unit, University College London, UK
    Mult Scler 14:1157-74. 2008
  7. ncbi A novel panel of cerebrospinal fluid biomarkers for the differential diagnosis of Alzheimer's disease versus normal aging and frontotemporal dementia
    A H Simonsen
    Biomarker Discovery Center Facility, Ciphergen Biosystems Inc, Copenhagen, Denmark
    Dement Geriatr Cogn Disord 24:434-40. 2007
  8. doi US-elastography in the differential diagnosis of benign and malignant thyroid nodules
    Carmela Asteria
    Department of Experimental Endocrinology and Cardiovascular Prevention, Policlinico Multimedica, IRCCS, Milan, Sesto San Giovanni, Italy
    Thyroid 18:523-31. 2008
  9. ncbi Detecting acute coronary syndrome in the emergency department with cardiac magnetic resonance imaging
    Raymond Y Kwong
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    Circulation 107:531-7. 2003
  10. doi Granulomatous lung disease: an approach to the differential diagnosis
    Sanjay Mukhopadhyay
    Department of Pathology, State University of New York Upstate Medical University, Syracuse, New York 13210, USA
    Arch Pathol Lab Med 134:667-90. 2010

Detail Information

Publications330 found, 100 shown here

  1. ncbi A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis
    Vanda A Lennon
    Department of Neurology, Mayo Clinic Rochester, Rochester, MN 55905, USA
    Lancet 364:2106-12. 2004
    ..We assessed the capacity of a putative marker for neuromyelitis optica (NMO-IgG) to distinguish neuromyelitis optica and related disorders from multiple sclerosis...
  2. ncbi Revised diagnostic criteria for neuromyelitis optica
    D M Wingerchuk
    Department of Neurology, Mayo Clinic College of Medicine, Scottsdale, AZ 85259, USA
    Neurology 66:1485-9. 2006
    ..A serum autoantibody marker, NMO-IgG, is highly specific for NMO. The authors propose revised NMO diagnostic criteria that incorporate NMO-IgG status...
  3. ncbi Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease
    G M McKhann
    Department of Neurology, Zanvyl Krieger Mind Brain Institute, Johns Hopkins University School of Medicine, 338 Krieger Hall, 3400 N Charles St, Baltimore, MD 21218 2685, USA
    Arch Neurol 58:1803-9. 2001
    ..In addition, recommendations for the neuropathological criteria of FTD were reviewed, relative to classical neuropathology and modern molecular biology...
  4. ncbi Real-time ultrasound elastography in the differential diagnosis of benign and malignant thyroid nodules
    Yurong Hong
    Second Affiliated Hospital, Zhejiang University College of Medicine, Zhejiang, China
    J Ultrasound Med 28:861-7. 2009
    ..The purpose of this study was to evaluate the diagnostic utility of real-time ultrasound elastography in differentiating benign from malignant thyroid nodules...
  5. doi Differential diagnosis of hepatic tumors: value of contrast-enhanced harmonic sonography using the newly developed contrast agent, Sonazoid
    Kinuyo Hatanaka
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine, Osaka Sayama, Japan
    Intervirology 51:61-9. 2008
    To clarify the value of contrast-enhanced harmonic ultrasonography (US) with Sonazoid, a second-generation US contrast agent, in the differential diagnosis of liver tumors compared to dynamic CT.
  6. pmc Differential diagnosis of suspected multiple sclerosis: a consensus approach
    D H Miller
    Department of Inflammation, Institute of Neurology, NMR Research Unit, University College London, UK
    Mult Scler 14:1157-74. 2008
    ..A systematic process for exclusion of alternative diagnoses has not been defined. An International Panel of MS experts developed consensus perspectives on MS differential diagnosis.
  7. ncbi A novel panel of cerebrospinal fluid biomarkers for the differential diagnosis of Alzheimer's disease versus normal aging and frontotemporal dementia
    A H Simonsen
    Biomarker Discovery Center Facility, Ciphergen Biosystems Inc, Copenhagen, Denmark
    Dement Geriatr Cogn Disord 24:434-40. 2007
    ..An early and accurate diagnosis of Alzheimer's disease (AD) is important in order to initiate symptomatic treatment with currently approved drugs and will be of even greater importance with the advent of disease-modifying compounds...
  8. doi US-elastography in the differential diagnosis of benign and malignant thyroid nodules
    Carmela Asteria
    Department of Experimental Endocrinology and Cardiovascular Prevention, Policlinico Multimedica, IRCCS, Milan, Sesto San Giovanni, Italy
    Thyroid 18:523-31. 2008
    ..This technique has previously been shown to be useful in the differential diagnosis between benign and malignant tumors.
  9. ncbi Detecting acute coronary syndrome in the emergency department with cardiac magnetic resonance imaging
    Raymond Y Kwong
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    Circulation 107:531-7. 2003
    ..Managing chest pain in the emergency department remains a challenge with current diagnostic strategies. We hypothesized that cardiac MRI could accurately identify patients with possible or probable acute coronary syndrome...
  10. doi Granulomatous lung disease: an approach to the differential diagnosis
    Sanjay Mukhopadhyay
    Department of Pathology, State University of New York Upstate Medical University, Syracuse, New York 13210, USA
    Arch Pathol Lab Med 134:667-90. 2010
    ..Although most pathologists are aware of the need to exclude an infection in this setting, there is less familiarity with the specific histologic features that aid in the differential diagnosis.
  11. ncbi Thrombocytopenia in pregnancy: differential diagnosis, pathogenesis, and management
    Keith R McCrae
    Hematology Oncology, BRB3, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, 10900 Euclid Avenue, OH 44106 4937, USA
    Blood Rev 17:7-14. 2003
    ..In this review, we discuss the differential diagnosis of the more common causes of pregnancy-associated thrombocytopenia, and provide an overview of approaches ..
  12. ncbi Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study
    Harald Hampel
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Arch Gen Psychiatry 61:95-102. 2004
    ..Different tau phosphoepitopes can be sensitively detected in cerebrospinal fluid (CSF)...
  13. ncbi Intraocular tuberculosis--an update
    Vishali Gupta
    Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Surv Ophthalmol 52:561-87. 2007
    ....
  14. ncbi Olfaction and Parkinson's syndromes: its role in differential diagnosis
    Regina Katzenschlager
    The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
    Curr Opin Neurol 17:417-23. 2004
    ..We review recent advances related to its cause and its clinical relevance with respect to the differential diagnosis of Parkinsonian syndromes.
  15. ncbi Nodular lymphocyte-predominant Hodgkin lymphoma with nodules resembling T-cell/histiocyte-rich B-cell lymphoma: differential diagnosis between nodular lymphocyte-predominant Hodgkin lymphoma and T-cell/histiocyte-rich B-cell lymphoma
    Ludmila Boudova
    Department of Pathology, Josef Schneider Str 2, D 97080 Wurzburg, Germany
    Blood 102:3753-8. 2003
    ..They are linked by a morphologic and probably a biologic continuum, which renders the differential diagnosis difficult...
  16. ncbi Comparative study of conventional colonoscopy, chromoendoscopy, and narrow-band imaging systems in differential diagnosis of neoplastic and nonneoplastic colonic polyps
    Ming Yao Su
    Department of Gastroenterology and Hepatology, Lin Kou Medical Center, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Am J Gastroenterol 101:2711-6. 2006
    ..To identify the feasibility of the narrow-band imaging (NBI) method compared with that of conventional colonoscopy and chromoendoscopy for distinguishing neoplastic and nonneoplastic colonic polyps...
  17. ncbi Myofascial pain associated to trigger points: a literature review. Part 2: differential diagnosis and treatment
    Eduardo Vazquez-Delgado
    TMJ Disease and Orofacial Pain Unit of Master of Oral Surgery Degree Program, University of Kentucky Dental School, USA
    Med Oral Patol Oral Cir Bucal 15:e639-43. 2010
    ..Many clinical conditions are included in the differential diagnosis of myofascial pain associated to trigger points...
  18. doi DOG1 antibody in the differential diagnosis of gastrointestinal stromal tumors: a study of 1840 cases
    Markku Miettinen
    Department of Soft Tissue Pathology, Armed Forces Institute of Pathology, 6825 16th Street, NW, Building 54, Room G090, Washington, DC 20306 6000, USA
    Am J Surg Pathol 33:1401-8. 2009
    ..DOG1 should be added into the diagnostic panel evaluating GI and other abdominal tumors, but limitations in its sensitivity and specificity should be recognized...
  19. ncbi Characterization of neoplastic and normal human breast tissues with in vivo (1)H MR spectroscopy
    K A Kvistad
    MR Center, Medical Division, University Hospital, N 7006 Trondheim, Norway
    J Magn Reson Imaging 10:159-64. 1999
    ..Analysis of lipid signals did not contribute to differentiation between various breast lesions and tissues. J. Magn. Reson. Imaging 1999;10:159-164...
  20. pmc A genomic and transcriptomic approach for a differential diagnosis between primary and secondary ovarian carcinomas in patients with a previous history of breast cancer
    Jean Philippe Meyniel
    Department of Translational Research, Institut Curie, 26 Rue d Ulm, 75248 Paris, Cedex 05, France
    BMC Cancer 10:222. 2010
    ..The purpose of the present work was to develop genomic and transcriptomic tools to further refine the pathological diagnosis of ovarian tumors after a previous history of breast cancer...
  21. ncbi Burkitt's lymphoma: clinicopathologic features and differential diagnosis
    Judith A Ferry
    James Homer Wright Pathology Laboratories of the Massachusetts General Hospital and the Department of Pathology, Harvard Medical School, Boston, 02114, USA
    Oncologist 11:375-83. 2006
    ..The differential diagnosis of Burkitt's lymphoma is broad, and precise diagnosis based on histologic, immunophenotypic, and genetic ..
  22. doi Differential diagnosis of parkinsonism: a metabolic imaging study using pattern analysis
    Chris C Tang
    Center for Neurosciences, The Feinstein Institute for Medical Research, Manhasset, NY, USA
    Lancet Neurol 9:149-58. 2010
    ..We aimed to assess whether metabolic brain imaging combined with spatial covariance analysis could accurately discriminate patients with parkinsonism who had different underlying disorders...
  23. doi Levels of brain related proteins in cerebrospinal fluid: an aid in the differential diagnosis of parkinsonian disorders
    Radu Constantinescu
    Department of Neurology, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden
    Parkinsonism Relat Disord 15:205-12. 2009
    ..The initial differential diagnosis can be extremely challenging with major implications for prognosis...
  24. ncbi Banff '05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN')
    K Solez
    University of Alberta, Edmonton, Alberta, Canada
    Am J Transplant 7:518-26. 2007
    ..Participation of B cells in allograft rejection and genomics markers of rejection were also major subjects addressed by the conference...
  25. ncbi Does combined imaging of the pre- and postsynaptic dopaminergic system increase the diagnostic accuracy in the differential diagnosis of parkinsonism?
    Walter Koch
    Department of Nuclear Medicine, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
    Eur J Nucl Med Mol Imaging 34:1265-73. 2007
    ..quantitative information about the dopaminergic system would provide a higher diagnostic accuracy in the differential diagnosis of parkinsonism than specific striatal D(2) receptor binding alone...
  26. ncbi Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues
    Thomas M Ulbright
    Department of Pathology and Laboratory Medicine, Clarian Health Partners and Indiana University School of Medicine, Indianapolis, IN 46202 5280, USA
    Mod Pathol 18:S61-79. 2005
    ....
  27. ncbi Clinicopathological correlates in frontotemporal dementia
    John R Hodges
    Prince of Wales Medical Research Institute, The University of New South Wales, Randwick, New South Wales, Australia
    Ann Neurol 56:399-406. 2004
    ..Therefore, the pathological substrate can be predicted in a significant proportion of FTD patients, which has important implications for studies targeting mechanistic treatments...
  28. ncbi Characterization of lesions of the breast with proton MR spectroscopy: comparison of carcinomas, benign lesions, and phyllodes tumors
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Ngan Shing St, Shatin, Hong Kong, SAR China
    AJR Am J Roentgenol 181:1267-72. 2003
    ..All lesions were larger than 1.5 cm. Tumor Ki-67 proliferative index, tumor angiogenesis, and HER2/neu oncogene overexpression were evaluated by immunohistochemistry of the histologic material...
  29. ncbi Congenital malaria, an important differential diagnosis to consider when evaluating febrile infants of immigrant mothers
    Stefan Hagmann
    Division of Pediatric Infectious Diseases, Bronx Lebanon Hospital Center, Bronx, NY 10457, USA
    Pediatr Emerg Care 23:326-9. 2007
    ..Because of its nonspecific presentation with fever during the first 3 months of life, it is an important differential diagnosis when evaluating such infants with fever in the pediatric emergency department...
  30. doi Value of autoantibody analysis in the differential diagnosis of chronic cholestatic liver disease
    Piotr Milkiewicz
    Department of Medicine, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Clin Gastroenterol Hepatol 7:1355-60. 2009
    ....
  31. doi Comparative study of conventional colonoscopy, magnifying chromoendoscopy, and magnifying narrow-band imaging systems in the differential diagnosis of small colonic polyps between trainee and experienced endoscopist
    Chun Chao Chang
    Division of Gastroenterology, Department of Internal Medicine, Taipei Medical University Hospital and Digestive Disease Research Center, Taipei, Taiwan
    Int J Colorectal Dis 24:1413-9. 2009
    ..We compared the ability of a trainee and an experienced endoscopist in distinguishing between neoplastic polyps and nonneoplastic polyps by conventional white-light, magnifying narrow-band imaging (NBI), and magnifying chromoendoscopy...
  32. ncbi Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count
    Baha M Sibai
    Department of Obstetrics and Gynecology, University of Cincinnati, Cincinnati, Ohio 45267, USA
    Obstet Gynecol 103:981-91. 2004
    ..Recommendation for diagnosis, management, and counseling of these women is also provided based on results of recent studies and my own clinical experience...
  33. ncbi Differential diagnosis of tumours and tumour-like lesions of the infrapatellar (Hoffa's) fat pad: pictorial review with an emphasis on MR imaging
    C Helpert
    Department of Radiology, MRI Centre, Royal Orthopaedic Hospital, Birmingham B31 2AP, UK
    Eur Radiol 14:2337-46. 2004
    ..This pictorial review illustrates the spectrum of mass-like lesions that can affect the IFP, emphasizing the radiographic and MR findings that suggest a specific diagnosis...
  34. ncbi Evaluation of early-stage Parkinson's disease with 99mTc-TRODAT-1 imaging
    W S Huang
    Department of Nuclear Medicine, National Defense Medical Center, Tri-Service General Hospital, Taipei, Taiwan
    J Nucl Med 42:1303-8. 2001
    ..CONCLUSION: For clinical practice, 99mTc-TRODAT-1 may serve as a useful imaging agent for the early detection of Parkinson's disease...
  35. pmc Use of synthetic peptides derived from the antigens ESAT-6 and CFP-10 for differential diagnosis of bovine tuberculosis in cattle
    H M Vordermeier
    TB Research Group, Department of Bacterial Diseases, Veterinary Laboratories Agency Weybridge, New Haw, Addlestone KT15 3NB, United Kingdom
    Clin Diagn Lab Immunol 8:571-8. 2001
    ..In summary, our results demonstrate that this peptide cocktail can discriminate between M. bovis infection and BCG vaccination with a high degree of sensitivity and specificity...
  36. ncbi Abdominal tuberculosis: diagnosis by laparoscopy and colonoscopy
    Md Ibrarullah
    Department of Surgical Gastroenterology, SV Institute of Medical Sciences, Tirupati 517 507, AP, India
    Trop Gastroenterol 23:150-3. 2002
    ..Peritoneoscopy and colonoscopy provide semi-invasive access to the peritoneum, large intestine and ileocecal area. Information on the diagnostic yield of these two investigation in abdominal tuberculosis is scarce...
  37. ncbi The syndrome of mesial temporal lobe epilepsy with hippocampal sclerosis: clinical features and differential diagnosis
    R Mark Sadler
    Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Adv Neurol 97:27-37. 2006
  38. pmc CSF neurofilament proteins in the differential diagnosis of dementia
    D De Jong
    Department of Neurology, Radboud University Nijmegen Medical Centre, 6500 HB, Nijmegen, The Netherlands
    J Neurol Neurosurg Psychiatry 78:936-8. 2007
    ..Neurofilament (NF) proteins are major cytoskeletal constituents of neurons. Increased CSF NF levels may reflect neuronal degeneration...
  39. ncbi Differential diagnosis of large periapical lesions using cone-beam computed tomography measurements and biopsy
    James H S Simon
    Division of Surgical Therapeutic and Bioengineering Sciences, School of Dentistry, University of Southern California, Los Angeles, CA 90089 0641, USA
    J Endod 32:833-7. 2006
    This study compared the differential diagnosis of large periapical lesions (granuloma versus cyst) to traditional biopsy using Cone Beam Computed Tomography (CBCT), the NewTom 3G...
  40. ncbi Adrenal masses: characterization with combined unenhanced and delayed enhanced CT
    Elaine M Caoili
    Department of Radiology, University of Michigan Medical Center, 1500 E Medical Center Dr, Ann Arbor, MI 48109 9723, USA
    Radiology 222:629-33. 2002
    ..To assess the accuracy of a dedicated adrenal computed tomographic (CT) protocol...
  41. doi Intrahepatic cholangiocarcinoma and hepatocellular carcinoma: differential diagnosis with contrast-enhanced ultrasound
    Li Da Chen
    Department of Medical Ultrasonics, The First Affiliated Hospital, Institute of Diagnostic and Interventional Ultrasound, Sun Yat Sen University, 58 Zhongshan Road 2, Guangzhou 510080, China
    Eur Radiol 20:743-53. 2010
    ..We assessed the usefulness of contrast-enhanced ultrasound (CEUS) in the differentiation of intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC)...
  42. pmc DNA differential diagnosis of taeniasis and cysticercosis by multiplex PCR
    Hiroshi Yamasaki
    Department of Parasitology Animal Laboratory for Medical Research, Asahikawa Medical College, Asahikawa, Japan
    J Clin Microbiol 42:548-53. 2004
    Multiplex PCR was established for differential diagnosis of taeniasis and cysticercosis, including their causative agents...
  43. ncbi FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease
    Norman L Foster
    Center for Alzheimer s Care, Imaging and Research and Department of Neurology, University of Utah, USA
    Brain 130:2616-35. 2007
    ..fluorodeoxyglucose (FDG-PET) shows different patterns of hypometabolism in these disorders that might aid differential diagnosis. Six dementia experts with variable FDG-PET experience made independent, forced choice, diagnostic ..
  44. ncbi Diagnosis and differential diagnosis of trigeminal neuralgia
    Joanna M Zakrzewska
    Barts and The London, Queen Mary s School of Medicine and Dentistry, London, England, UK
    Clin J Pain 18:14-21. 2002
    ..Their specificity and sensitivity regarding compressions found at the time of surgery is reviewed. Other differential diagnoses for chronic unilateral orofacial pain are discussed...
  45. ncbi Sinonasal undifferentiated carcinoma: clinical and pathologic features and a discussion on classification, cellular differentiation, and differential diagnosis
    Asim Ejaz
    Department of Pathology and Laboratory Medicine, Continuum Hospitals of New York Beth Israel Medical Center and Saint Luke s Roosevelt Hospitals, New York, New York 10003, USA
    Adv Anat Pathol 12:134-43. 2005
    ....
  46. doi Pancreatic cysts: pathologic classification, differential diagnosis, and clinical implications
    Olca Basturk
    Department of Pathology, New York University, New York, New York, USA
    Arch Pathol Lab Med 133:423-38. 2009
    ..Consequently, in the past 2 decades, the nature of many cystic tumors in this organ has been better characterized, and significant developments have taken place in the classification and in our understanding of pancreatic cystic lesions...
  47. ncbi Dopamine transporter loss visualized with FP-CIT SPECT in the differential diagnosis of dementia with Lewy bodies
    John T O'Brien
    Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, England
    Arch Neurol 61:919-25. 2004
    ..Dementia with Lewy bodies (DLB) is a common form of late-life dementia that can be difficult to differentiate from other disorders, especially Alzheimer disease (AD), during life. At autopsy the striatal dopaminergic transporter is reduced...
  48. ncbi Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob disease
    M Otto
    Neurologische Klinik und Poliklinik, Georg August Universitat Gottingen, Germany
    Neurology 58:192-7. 2002
    ..Both tests in a larger group of patients with the differential diagnosis of CJD were evaluated.
  49. ncbi Asthma and chronic obstructive pulmonary disease exhibit common origins in any country!
    Monica Kraft
    Am J Respir Crit Care Med 174:238-40; discussion 243-4. 2006
  50. ncbi Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease
    A J Hughes
    United Kingdom Parkinson's Disease Society Brain Research Centre, Institute of Neurology, London, UK
    Neurology 57:1497-9. 2001
    ..Assessment of the clinical features suggests that an accuracy of 90% may be the highest that can be expected using current diagnostic criteria...
  51. ncbi Alzheimer's disease versus dementia with Lewy bodies: cerebral metabolic distinction with autopsy confirmation
    S Minoshima
    Department of Internal Medicine, University of Michigan Medical School, Geriatrics Research, Education, and Clinical Center, Ann Arbor, USA
    Ann Neurol 50:358-65. 2001
    ..In these patients, occipital hypometabolism preceded some clinical features of DLB. Occipital hypometabolism is a potential antemortem marker to distinguish DLB versus AD...
  52. pmc Differential diagnosis of Trichostrongylus and hookworm eggs via PCR using ITS-1 sequence
    Tai Soon Yong
    Department of Parasitology and Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul 120 752, Korea
    Korean J Parasitol 45:69-74. 2007
    ..duodenale and N. americanus from the eggs of each (520 bp, 690 bp, and 870 bp, respectively). A species-specific PCR technique can be developed in order to study the epidemiology of Trichostrongylus spp. and hookworms in endemic areas...
  53. doi Performance of transient elastography for the staging of liver fibrosis: a meta-analysis
    Mireen Friedrich-Rust
    Department of Internal Medicine I, J W Goethe University Hospital, Frankfurt, Germany
    Gastroenterology 134:960-74. 2008
    ..A meta-analysis was performed to assess the overall performance of transient elastography for the diagnosis of liver fibrosis and to analyze factors influencing the diagnostic accuracy...
  54. ncbi Fabry disease defined: baseline clinical manifestations of 366 patients in the Fabry Outcome Survey
    A Mehta
    University College London, London, UK
    Eur J Clin Invest 34:236-42. 2004
    ..This paper presents the first analysis of the FOS database and provides essential baseline data against which the effects of enzyme replacement can be measured...
  55. ncbi Inflammatory pseudotumor of the liver: demographics, diagnosis, and the case for nonoperative management
    Jonathan B Koea
    Upper Gastrointestinal Hepatobiliary Unit, Department of Surgery, Auckland Hospital, Auckland, New Zealand
    J Am Coll Surg 196:226-35. 2003
    Inflammatory pseudotumor of the liver (IPL) is an unusual tumor-like condition that is becoming recognized as an important differential diagnosis in the patient presenting with liver masses. This report describes six cases of IPL.
  56. ncbi Rapid and differential diagnosis of foot-and-mouth disease, swine vesicular disease, and vesicular stomatitis by a new multiplex RT-PCR assay
    Jovita Fernández
    Centro de Investigación en Sanidad Animal CISA INIA, Valdeolmos, Madrid, Spain
    J Virol Methods 147:301-11. 2008
    ..experimentally, showing the suitability of the method for a rapid (less than 6h), sensitive and specific differential diagnosis in clinical samples...
  57. ncbi Gastrointestinal stromal tumors--definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis
    M Miettinen
    Department of Soft Tissue Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
    Virchows Arch 438:1-12. 2001
    ..Angiosarcomas and metastatic melanomas, both of which are often KIT-positive, should not be confused with GISTs...
  58. ncbi Application of an immunodiagnostic method for improving preoperative diagnosis of nodular thyroid lesions
    A Bartolazzi
    Department of Oncology Pathology, Cellular and Molecular Tumor Pathology, Cancer Center Karolinska, CCK R8 04 Karolinska Hospital, 17176, Stockholm, Sweden
    Lancet 357:1644-50. 2001
    ..We undertook an international multicentre study to assess the usefulness of immunohistocytochemical staining for two potential markers of malignant thyrocytes...
  59. ncbi Neuroendocrine differentiated breast carcinoma: imaging features correlated with clinical and histopathological findings
    Işil Gunhan-Bilgen
    Department of Radiology, Ege University Hospital, Bornova, 35100 Izmir, Turkey
    Eur Radiol 13:788-93. 2003
    ..Neuroendocrine differentiated breast carcinoma should be included in the differential diagnosis of mammographically dense, round masses with predominantly spiculated or lobulated margins...
  60. ncbi Erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis: acute ocular manifestations, causes, and management
    Yi Sheng Chang
    Department of Ophthalmology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Cornea 26:123-9. 2007
    ..To study the acute ocular/cutaneous manifestations, causes, and management of the erythema multiforme (EM)/Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) disease spectrum...
  61. ncbi Molecular diagnostics of viral hemorrhagic fevers
    Christian Drosten
    Department of Virology, Bernhard Nocht Institute of Tropical Medicine, Bernhard Nocht Strasse 74, 20359 Hamburg, Germany
    Antiviral Res 57:61-87. 2003
    ..The third part is focussed on important differential diagnoses of VHF...
  62. doi Diagnosis and differential diagnosis of fibromyalgia
    Don L Goldenberg
    Department of Rheumatology, Newton Wellesley Hospital, Newton, Massachusetts 02462, USA
    Am J Med 122:S14-21. 2009
    ..Until a better clinical case definition of fibromyalgia exists, all diagnostic criteria should be interpreted with caution, considered rudimentary, and subject to modification...
  63. ncbi Inflammatory pseudotumor
    Lakshmana Das Narla
    Department of Radiology, Medical College of Virginia VCU Health System, Main Hospital 3rd Fl, 1250 E Marshall St, Richmond, VA 23298, USA
    Radiographics 23:719-29. 2003
    ..Because inflammatory pseudotumors mimic malignant tumors both clinically and radiologically, the radiologist should be familiar with this entity and help avoid unnecessary radical surgery when possible...
  64. ncbi Use of the percentage of free prostate-specific antigen to enhance differentiation of prostate cancer from benign prostatic disease: a prospective multicenter clinical trial
    W J Catalona
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    JAMA 279:1542-7. 1998
    ..The percentage of free prostate-specific antigen (PSA) in serum has been shown to enhance the specificity of PSA testing for prostate cancer detection, but earlier studies provided only preliminary cutoffs for clinical use...
  65. ncbi Chromoendoscopy using indigo carmine dye spraying with magnifying observation is the most reliable method for differential diagnosis between non-neoplastic and neoplastic colorectal lesions: a prospective study
    K I Fu
    Division of Gastrointestinal Oncology and Digestive Endoscopy, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    Endoscopy 36:1089-93. 2004
    b>Differential diagnosis between non-neoplastic and neoplastic lesions is very important at colonoscopy, since removal or biopsy of non-neoplastic polyps wastes time and resources...
  66. ncbi Evaluating human breast ductal carcinomas with high-resolution magic-angle spinning proton magnetic resonance spectroscopy
    L L Cheng
    Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, 02129, USA
    J Magn Reson 135:194-202. 1998
    ..Our results suggest that biochemical markers thus measured may function as a valuable adjunct to histopathology to improve the accuracy of and reduce the time frame required for the diagnosis of human breast cancer...
  67. ncbi Diagnosis and management of superficial bladder cancer
    C L Amling
    Department of Urology, Naval Medical Center, San Diego, California, USA
    Curr Probl Cancer 25:219-78. 2001
    ..With the development of orthotopic lower urinary tract reconstruction to the native urethra, the quality of life impact of radical cystectomy has been lessened...
  68. ncbi Against the Dutch hypothesis: asthma and chronic obstructive pulmonary disease are distinct diseases
    Peter J Barnes
    Am J Respir Crit Care Med 174:240-3; discussion 243-4. 2006
  69. ncbi CT screening for lung cancer: suspiciousness of nodules according to size on baseline scans
    Claudia I Henschke
    Department of Radiology and Medicine, Weill Medical College of Cornell University, 525 E 68th St, New York, NY 10021, USA
    Radiology 231:164-8. 2004
    ..0 mm in diameter identified on initial computed tomographic (CT) images at baseline screening leads to a diagnosis of malignancy prior to first annual repeat screening, compared with a possibly optimal work-up of larger nodules...
  70. ncbi Enigmatic Kikuchi-Fujimoto disease: a comprehensive review
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, University of Barcelona, Spain
    Am J Clin Pathol 122:141-52. 2004
    ..There is an abundance of T cells with predominance of CD8+ over CD4+ T cells. Differential diagnosis includes lymphoma, lymphadenitis associated with systemic lupus erythematosus, and even adenocarcinoma...
  71. ncbi Clinicopathologic analysis of frontotemporal and corticobasal degenerations and PSP
    K A Josephs
    Division of Movement Disorders, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 66:41-8. 2006
    ..To examine the relationship between early clinical features, pathologies, and biochemistry of the frontotemporal lobar degenerations (FTLDs), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD)...
  72. ncbi Splenic metastases: clinicopathologic presentation, differential diagnosis, and pathogenesis
    Eva Comperat
    Service d Anatomie Pathologique, Hopital Pitie Salpetriere, Boulevard de l Hopital, 75013 Paris, France
    Arch Pathol Lab Med 131:965-9. 2007
    ..Splenic metastases occur in a context of multivisceral disseminated cancer or as a solitary lesion...
  73. ncbi Primary Ewing's sarcoma/primitive neuroectodermal tumor of the kidney: a clinicopathologic and immunohistochemical analysis of 11 cases
    Rafael E Jimenez
    Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA
    Am J Surg Pathol 26:320-7. 2002
    ..FLI-1 and WT-1 immunohistochemistry may be valuable in this differential diagnosis, given the known immunophenotypic overlap between ES/PNET and blastema-predominant WT with regard to CD99, ..
  74. ncbi Consensus definitions proposed for pediatric multiple sclerosis and related disorders
    Lauren B Krupp
    National Pediatric MS Center, Stony Brook University Medical Center, Stony Brook, NY 11794 8121, USA
    Neurology 68:S7-12. 2007
    ..Clinical, biologic, and radiographic delineation of the various monophasic and chronic childhood demyelinating disorders requires an operational classification system to facilitate prospective research studies...
  75. doi Determinants of symptoms in functional dyspepsia: gastric sensorimotor function, psychosocial factors or somatisation?
    L Van Oudenhove
    Department of Pathophysiology, Gastroenterology Section, University of Leuven and University Hospital Gasthuisberg, Leuven, Belgium
    Gut 57:1666-73. 2008
    ..Gastric sensorimotor dysfunction, psychosocial factors and somatisation are all implicated in symptom generation in functional dyspepsia (FD)...
  76. ncbi Sonographic features of benign thyroid nodules: interobserver reliability and overlap with malignancy
    Jeffrey R Wienke
    Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    J Ultrasound Med 22:1027-31. 2003
    ..To prospectively determine the sonographic findings of nodular hyperplasia of the thyroid, to compare these with reported findings associated with malignancy, and to assess interobserver reliability...
  77. ncbi ST-segment elevation in conditions other than acute myocardial infarction
    Kyuhyun Wang
    Hennepin County Medical Center, Cardiology Division, University of Minnesota, Minneapolis, MN 55415, USA
    N Engl J Med 349:2128-35. 2003
  78. doi Hyperfibrinolysis after major trauma: differential diagnosis of lysis patterns and prognostic value of thrombelastometry
    Herbert Schöchl
    Department of Anesthesiology and Intensive Care, AUVA Trauma Hospital, Salzburg, Austria
    J Trauma 67:125-31. 2009
    ..Furthermore, routine laboratory based and the rotational thrombelastometry analyzer (ROTEM)-derived variables were also correlated with survival...
  79. ncbi Recognizing and treating diabetic autonomic neuropathy
    A I Vinik
    the Strelitz Diabetes Research Institutes, Department of Internal Medicine and Anatomy/Neurobiology, Eastern Virginia Medical School, Norfolk, USA
    Cleve Clin J Med 68:928-30, 932, 934-44. 2001
    ..Strict glycemic control can slow the onset of diabetic autonomic neuropathy and sometimes reverse it. Pharmacologic and nonpharmacologic therapies are available to treat symptoms...
  80. ncbi Value of 123I-MIBG radioactivity in the differential diagnosis of DLB from AD
    M Yoshita
    Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Neurology 66:1850-4. 2006
    ..To evaluate the diagnostic reliability of cardiac iodine-123 metaiodobenzylguanidine ((123)I-MIBG) radioactivity in discriminating dementia with Lewy bodies (DLB) from Alzheimer disease (AD) regardless of parkinsonism...
  81. doi Utility of elastography for differential diagnosis of benign and malignant thyroid nodules
    Ryoji Kagoya
    Department of Otolaryngology, Hitachi General Hospital, Hitachi, Japan
    Otolaryngol Head Neck Surg 143:230-4. 2010
    ....
  82. ncbi Differential diagnosis of small single solid thyroid nodules using real-time ultrasound elastography
    Y Wang
    Department of Ultrasound in Medicine, The Sixth People s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China
    J Int Med Res 38:466-72. 2010
    ..It is concluded that real-time USE is a promising imaging technique that could assist in the differential diagnosis of single solid thyroid nodules < 10 mm in maximum diameter that give indeterminate results on ..
  83. doi Magnifying endoscopy combined with narrow-band imaging for differential diagnosis of superficial depressed gastric lesions
    M Kaise
    Department of Endoscopy, The Jikei University School of Medicine, Tokyo, Japan
    Endoscopy 41:310-5. 2009
    Magnifying endoscopy combined with narrow-band imaging (ME-NBI) has been used for differential diagnosis of various focal lesions...
  84. ncbi Utility of 2-[18F] fluoro-2-deoxy-D-glucose positron emission tomography in differential diagnosis of benign and malignant intraductal papillary-mucinous neoplasm of the pancreas
    Yoshito Tomimaru
    Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Oncol Rep 24:613-20. 2010
    ..5 offered the best diagnosis of malignant IPMN. These results suggest that FDG-PET is useful for differentiation of malignant IPMN of the pancreas, and that it should be performed in combination with other conventional imaging modalities...
  85. doi Differential diagnosis between benign and malignant gallbladder diseases with real-time contrast-enhanced ultrasound
    Xiao Hua Xie
    Department of Medical Ultrasonics, The First Affiliated Hospital, Institute of Diagnostic and Interventional Ultrasound, Sun Yat Sen University, 58 Zhongshan Road 2, Guangzhou 510080, People s Republic of China
    Eur Radiol 20:239-48. 2010
    The value of contrast-enhanced ultrasound (CEUS) in differential diagnosis between benign and malignant gallbladder diseases was investigated...
  86. pmc Identification of cytokines in whole blood for differential diagnosis of tuberculosis versus pneumonia
    Wen Lin Su
    Graduate Institute of Medical Sciences, National Defense Medical Center, No 161, Sec 6, Mincyuan E Rd, Neihu District, Taipei City 114, Taiwan, Republic of China
    Clin Vaccine Immunol 17:771-7. 2010
    ..The percent change in IFN-gamma and IL-12 after LPS stimulation of whole blood cells could differentiate patients with pneumonia from patients with TB...
  87. ncbi Combined detection of serum tumor markers for differential diagnosis of solid lesions located at the pancreatic head
    Quan Liao
    Department of General Surgery, Peking Union Medical College Hospital, Beijing 100730, China
    Hepatobiliary Pancreat Dis Int 6:641-5. 2007
    The differential diagnosis of solid lesions located at the pancreatic head is very important for choosing therapies and setting up surgical tactics...
  88. doi Differential diagnosis for intrahepatic biliary cystadenoma and hepatic simple cyst: significance of cystic fluid analysis and radiologic findings
    Hyo Kyung Choi
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Clin Gastroenterol 44:289-93. 2010
    This study evaluated the significance of cystic fluid analysis and radiologic findings in the differential diagnosis of biliary cystadenomas (BCA) and hepatic simple cysts (HSCs).
  89. ncbi Using gene expression profiling to differentiate benign versus malignant thyroid tumors
    Chiara Mazzanti
    Surgery Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Res 64:2898-903. 2004
    ..Lancet 2003;361:501-11). In the past few decades, no improvement has been made in the differential diagnosis of thyroid tumors by fine needle aspiration biopsy, specifically suspicious or indeterminate thyroid ..
  90. doi Urticarial lesions: if not urticaria, what else? The differential diagnosis of urticaria: part II. Systemic diseases
    Anna Peroni
    Department of Biomedical and Surgical Sciences, Section of Dermatology and Venereology, University of Verona, Verona, Italy
    J Am Acad Dermatol 62:557-70; quiz 571-2. 2010
    ..All of these conditions may enter into the differential diagnosis of ordinary urticaria...
  91. pmc Prospective two year follow up study comparing novel and conventional imaging procedures in patients with arthritic finger joints
    M Backhaus
    Department of Rheumatology and Clinical Immunology, Charite University Hospital, Humboldt University of Berlin, Germany
    Ann Rheum Dis 61:895-904. 2002
    ..Additionally, to study the course of soft tissue lesions depicted in the initial study in comparison with the clinical findings...
  92. ncbi Clinical signs and symptoms predicting influenza infection
    A S Monto
    University of Michigan, 3080 SPH 1, 109 Observatory St, Ann Arbor, MI 48109 2029, USA
    Arch Intern Med 160:3243-7. 2000
    ..In clinical practice, antiviral use has rarely been guided by antecedent laboratory diagnosis. Defined clinical predictors of an influenza infection can help guide timely therapy and avoid unnecessary antibiotic use...
  93. pmc Which neuropsychiatric and behavioural features distinguish frontal and temporal variants of frontotemporal dementia from Alzheimer's disease?
    S Bozeat
    MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, UK
    J Neurol Neurosurg Psychiatry 69:178-86. 2000
    ..To establish whether the frontal and temporal variants of FTD are characterised by different behavioural changes...
  94. pmc False positive and false negative FDG-PET scans in various thoracic diseases
    Jung Min Chang
    Department of Radiology, Seoul National University Hospital, Seoul, Korea
    Korean J Radiol 7:57-69. 2006
    ..In this review, we illustrate false positive and negative findings of PET scan in a variety of diseases...
  95. ncbi Differences in clinical features between influenza A H1N1, A H3N2, and B in adult patients
    Masahide Kaji
    Kurume University Medical Center, Department of Internal Medicine, Japan
    Respirology 8:231-3. 2003
    ..The differences in clinical features between influenza A H1N1, A H3N2, and B in the past three influenza seasons were examined...
  96. ncbi Effectiveness versus efficacy: the limited value in clinical practice of high dose dexamethasone suppression testing in the differential diagnosis of adrenocorticotropin-dependent Cushing's syndrome
    D C Aron
    Division of Clinical and Molecular Endocrinology, Department of Veterans Affairs Medical Center, and Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    J Clin Endocrinol Metab 82:1780-5. 1997
    ..regression models indicate that the results of the dexamethasone suppression test add little to the differential diagnosis of ACTH-dependent Cushing's syndrome, especially after taking other clinical information into account...
  97. doi A reevaluation of the primary diagnosis of hemangiopericytoma and the clinical importance of differential diagnosis from solitary fibrous tumor of the central nervous system
    Yutaka Hayashi
    Department of Neurosurgery, Kanazawa University Hospital, Kanazawa, Japan
    Clin Neurol Neurosurg 111:34-8. 2009
    ..We also compared the clinical features of these cases...
  98. ncbi Investigation of risk factors in children with arterial ischemic stroke
    Vijeya Ganesan
    Neurosciences Unit, University College London, United Kingdom
    Ann Neurol 53:167-73. 2003
    ..Cerebral arterial imaging is usually abnormal, but echocardiography and prothrombotic screening are commonly negative...
  99. ncbi Significance of the fractional excretion of urea in the differential diagnosis of acute renal failure
    Christos P Carvounis
    Department of Medicine, Division of Nephrology, Nassau University Medical Center and State University of New York atStony Brook, East Meadow, New York 11554, USA
    Kidney Int 62:2223-9. 2002
    ..In contrast, the fractional excretion of urea nitrogen (FEUN) is primarily dependent on passive forces and is therefore less influenced by diuretic therapy...
  100. doi Copeptin in the differential diagnosis of hyponatremia
    Wiebke Fenske
    Endocrinology and Diabetes Unit, Department of Medicine I, University of Wurzburg, Josef Schneider Strasse 2, D 97080 Wurzburg, Germany
    J Clin Endocrinol Metab 94:123-9. 2009
    ..This study was designed to evaluate the diagnostic potential of copeptin, the C-terminal part of provasopressin, as a new marker in the differential diagnosis of hyponatremia.
  101. ncbi Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirus
    Ann M Powers
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA
    J Gen Virol 88:2363-77. 2007

Research Grants77

  1. Rapid Diagnosis of Monkeypox and Smallpox Infections
    John Fitchen; Fiscal Year: 2007
    ..orthopoxvirus infection and for this reason we will also develop rapid VZV-specific tests to use for differential diagnosis. Using an integrated dual-detection system, these novel diagnostic tests will combine serological analysis ..
  2. Measuring Altered Social Behavior in Neurodegenerative Disease
    Katherine P Rankin; Fiscal Year: 2010
    ..The resulting battery could be used by clinicians 1) to aid in the differential diagnosis of dementia;2) to provide treatment interventions, prognostic information, and caregiver support based on ..
  3. WIDEBAND CLINICAL DIAGNOSIS AND MONITORING OF MIDDLE-EAR AND COCHLEAR FUNCTION
    DOUGLAS KEEFE; Fiscal Year: 2009
    ..The research also evaluates whether the test battery improves the accuracy of diagnosing middle-ear disease and of identifying hearing loss in adult patients who receive medications that may affect their hearing. ..
  4. Measuring Altered Social Behavior in Neurodegenerative Disease
    Katherine Rankin; Fiscal Year: 2009
    ..The resulting battery could be used by clinicians 1) to aid in the differential diagnosis of dementia; 2) to provide treatment interventions, prognostic information, and caregiver support based on ..
  5. Molecular Classification of Suspicious Thyroid Tumors
    Martha Zeiger; Fiscal Year: 2009
    A. SPECIFIC AIMS Diagnostic Dilemma in the Differential Diagnosis of a Suspicious Thyroid Nodule...
  6. Dengue Epitope Vaccine,Tetravalent & MHCII-Targeted
    J Thomas August; Fiscal Year: 2007
    ..A novel PCR assay will be used for differential diagnosis of dengue serotypes and other diseases (Project 3)...
  7. Microarray analysis of thyroid neoplasm
    Martha Zeiger; Fiscal Year: 2004
    Although fine needle aspiration (FNA) cytology is the best diagnostic tool in the differential diagnosis of a thyroid nodule, it often cannot differentiate a benign from a malignant lesion...
  8. Middle-ear Mechanics in Normal and Pathological Ears
    Saumil N Merchant; Fiscal Year: 2010
    ..Our work has a) resulted in new tests employing laser vibrometry for improved preoperative differential diagnosis of ossicular lesions in patients with an intact tympanic membrane, and b) provided specific surgical ..
  9. Middle-ear Mechanics in Normal and Pathological Ears
    SAUMIL MERCHANT; Fiscal Year: 2007
    ..Our work has a) resulted in new tests employing laser vibrometry for improved preoperative differential diagnosis of ossicular lesions in patients with an intact tympanic membrane, and b) provided specific surgical ..
  10. Middle-ear Mechanics in Normal and Pathological Ears
    SAUMIL MERCHANT; Fiscal Year: 2009
    ..Our work has a) resulted in new tests employing laser vibrometry for improved preoperative differential diagnosis of ossicular lesions in patients with an intact tympanic membrane, and b) provided specific surgical ..
  11. Multi-peptide assay for serodiagnosis of Lyme disease
    Maria Gomes Solecki; Fiscal Year: 2007
    ..affects multiple organ systems including musculoskeletal, skin and nervous system and is included in the differential diagnosis of multiple diseases...
  12. Melanocortin Signaling in Feeding Behavior
    ROGER CONE; Fiscal Year: 2007
    ..understanding of the central melanocortin system will increase our understanding of obesity, improve differential diagnosis of obesity syndromes, and ultimately identify potential targets for drug development for the treatment of ..
  13. Comprehensive Molecular Diagnosis for Food and Waterborne Enteropathogens
    Eric Houpt; Fiscal Year: 2007
    ..for referral public health laboratories to detect the multiplicity of potential pathogens that inhabit the differential diagnosis of a food or waterborne diarrheal outbreak...