bronchospirometry

Summary

Summary: Spirometric technique in which the volume of air breathed in the right and left lung is recorded separately.

Top Publications

  1. ncbi Effect of a very late antigen-4 receptor antagonist on allergen-induced airway responses and inflammation in asthma
    Z Diamant
    Erasmus University Medical Centre, Lung Function Lab, Rotterdam, The Netherlands
    Clin Exp Allergy 35:1080-7. 2005
  2. pmc Dynamic hyperinflation is associated with a poor cardiovascular response to exercise in COPD patients
    Panagiota Tzani
    Cardiopulmonary Dept, Lung Function Unit, University Hospital via Rasori 10, Parma 43125, Italy
    Respir Res 12:150. 2011
  3. pmc The clinical features of the overlap between COPD and asthma
    Megan Hardin
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Respir Res 12:127. 2011
  4. pmc Effect of inhaled dust mite allergen on regional particle deposition and mucociliary clearance in allergic asthmatics
    W D Bennett
    Center for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Clin Exp Allergy 41:1719-28. 2011
  5. doi Using the theory of planned behavior to predict the use of incentive spirometry among cardiac surgery patients in Taiwan
    Heng Hsin Tung
    Department of Nursing, National Taipie University of Nursing and Health Science, Tungs Taichung Metroharbor Hospital, Taipei, Taiwan
    Heart Lung 40:440-7. 2011
  6. ncbi Assessing two spirometric criteria of pre-bronchodilator and post-bronchodilator FEV1/FVC ratio in detecting air flow obstruction
    Zeeshan Waheed
    Section of Pulmonary and Critical Care Medicine, Department of Medicine, The Aga Khan University Hospital, Karachi, Pakistan
    J Pak Med Assoc 61:1172-5. 2011
  7. ncbi Are antihistamines useful in managing asthma?
    Andrew M Wilson
    Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK
    Curr Opin Allergy Clin Immunol 2:53-9. 2002
  8. ncbi Expression of bronchodilator response: comparison of four indices
    S K Chhabra
    Department of Cardiorespiratory Physiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi 110007, India
    Respir Med 96:611-4. 2002
  9. ncbi Bronchial hyperreactivity and spirometric impairment in patients with seasonal allergic rhinitis
    Giorgio Ciprandi
    Dipartimento Regionale Testa Collo, Padiglione Specialità piano terzo, Ospedale San Martino, Largo R Benzi 10, Genoa 16132, Italy
    Respir Med 98:826-31. 2004
  10. ncbi [Effective control of a severe exacerbation of bronchial asthma]
    V I Makolkin
    Ter Arkh 76:46-50. 2004

Research Grants

Scientific Experts

  • Megan Hardin
  • Panagiota Tzani
  • William D Bennett
  • M K Narula
  • Matthew Hegewald
  • James Jason Miller
  • Sunil K Chhabra
  • G Liistro
  • J M Tunon-de-Lara
  • Z Diamant
  • T Seppanen
  • Rui Jiang
  • G Ciprandi
  • Meredith C McCormack
  • Roberto de Marco
  • J M Vernejoux
  • Andrew M Wilson
  • HUBERT FORSTER
  • Heng Hsin Tung
  • Zeeshan Waheed
  • Laura Bozomitu
  • Maria R Bonsignore
  • Gustavo J Rodrigo
  • Christene R McLachlan
  • Gary M Hunninghake
  • S J Kim
  • Michelle R Zeidler
  • G Woszczek
  • V I Makolkin
  • K Wiedemann
  • A Saarinen
  • A S Pelkonen
  • Muhammad Irfan
  • Chiu Mieh Huang
  • Javaid Ahmed Khan
  • Najmul Hasan Siddiqui
  • Chun Che Shih
  • Beenish Syed
  • Ming Shan Jan
  • Safia Awan
  • Cheu Ye Liau
  • Ahmed Suleman Haque
  • Chung Yi Chang
  • G Aprodu
  • D Moraru
  • M Burlea
  • B Stana
  • D A Taylor
  • Evelina Moraru
  • Fabio Cibella
  • Stefania La Grutta
  • Giuseppina Cuttitta
  • M Rodriguez-Carballeira
  • Margherita Marchese
  • Marco Virzi'
  • Anna Bonanno
  • Mirella Profita
  • R A Feinstein
  • Mario Veca
  • Nicola Scichilone
  • Giuseppe Morici
  • H Kawalski
  • T Manczur
  • Amelia Interrante
  • S Kannisto
  • Avis Williamson
  • Richie Poulton
  • Justina M Greene
  • Jody S Sylvia
  • Juan C Celedon
  • Manuel E Soto-Quiros
  • Barbara J Klanderman
  • Ngoc P Ly
  • George Car
  • D Robin Taylor
  • Lydiana Avila
  • Jan Cowan
  • David Welch
  • Robert J Hancox
  • Catherine Liang
  • Susan Filsell
  • Edwin K Silverman
  • Malcolm R Sears
  • M H Suk
  • C Shin
  • Hyun J Kim
  • J J Shim
  • S W Melanson
  • Jeffrey M Silverman
  • Donald P Tashkin

Detail Information

Publications71

  1. ncbi Effect of a very late antigen-4 receptor antagonist on allergen-induced airway responses and inflammation in asthma
    Z Diamant
    Erasmus University Medical Centre, Lung Function Lab, Rotterdam, The Netherlands
    Clin Exp Allergy 35:1080-7. 2005
    ..Very late antigen-4 (VLA(4)) plays a key role in the recruitment of eosinophils in allergic responses in animal studies...
  2. pmc Dynamic hyperinflation is associated with a poor cardiovascular response to exercise in COPD patients
    Panagiota Tzani
    Cardiopulmonary Dept, Lung Function Unit, University Hospital via Rasori 10, Parma 43125, Italy
    Respir Res 12:150. 2011
    ..The aim of this study was to investigate the relationship between dynamic hyperinflation and cardiovascular response to maximal exercise in COPD patients...
  3. pmc The clinical features of the overlap between COPD and asthma
    Megan Hardin
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Respir Res 12:127. 2011
    ..The coexistence of COPD and asthma is widely recognized but has not been well described. This study characterizes clinical features, spirometry, and chest CT scans of smoking subjects with both COPD and asthma...
  4. pmc Effect of inhaled dust mite allergen on regional particle deposition and mucociliary clearance in allergic asthmatics
    W D Bennett
    Center for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Clin Exp Allergy 41:1719-28. 2011
    ..Acute exacerbations in allergic asthmatics may lead to impaired ability to clear mucus from the airways, a key factor in asthma morbidity...
  5. doi Using the theory of planned behavior to predict the use of incentive spirometry among cardiac surgery patients in Taiwan
    Heng Hsin Tung
    Department of Nursing, National Taipie University of Nursing and Health Science, Tungs Taichung Metroharbor Hospital, Taipei, Taiwan
    Heart Lung 40:440-7. 2011
    ..The use of incentive spirometry (IS) is reported to prevent and treat postoperative pulmonary complications. This study sought to use the theory of planned behavior to predict the use of IS in this population...
  6. ncbi Assessing two spirometric criteria of pre-bronchodilator and post-bronchodilator FEV1/FVC ratio in detecting air flow obstruction
    Zeeshan Waheed
    Section of Pulmonary and Critical Care Medicine, Department of Medicine, The Aga Khan University Hospital, Karachi, Pakistan
    J Pak Med Assoc 61:1172-5. 2011
    ..To assess the Pre-bronchodilator criteria and the Post-bronchodilator criteria of FEV1/FVC ratio in diagnosing Airflow obstruction...
  7. ncbi Are antihistamines useful in managing asthma?
    Andrew M Wilson
    Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK
    Curr Opin Allergy Clin Immunol 2:53-9. 2002
    ..This combination has an anti-asthmatic effect that is greater than that of either drug given alone and may be comparable to inhaled corticosteroid therapy...
  8. ncbi Expression of bronchodilator response: comparison of four indices
    S K Chhabra
    Department of Cardiorespiratory Physiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi 110007, India
    Respir Med 96:611-4. 2002
    ..Although all other methods had limitations, delta FEV1 and delta FEV1% predicted appeared to be better indices...
  9. ncbi Bronchial hyperreactivity and spirometric impairment in patients with seasonal allergic rhinitis
    Giorgio Ciprandi
    Dipartimento Regionale Testa Collo, Padiglione Specialità piano terzo, Ospedale San Martino, Largo R Benzi 10, Genoa 16132, Italy
    Respir Med 98:826-31. 2004
    ..Thus, the present study aimed at evaluating a group of subjects suffering from seasonal allergic rhinitis alone to investigate the presence of spirometric impairment and BHR both during and outside the pollen season...
  10. ncbi [Effective control of a severe exacerbation of bronchial asthma]
    V I Makolkin
    Ter Arkh 76:46-50. 2004
    ..To evaluate effectiveness and safety of nebulizer therapy (NT) with broncholytics and pulmicort suspension (PS) in patients with a severe exacerbation of bronchial asthma (BA)...
  11. ncbi [Separation of the airways: historical aspects]
    K Wiedemann
    Abt, für Anästhesiologie und Intensivmedizin, Thoraxklinik Heidelberg, Germany
    Anasthesiol Intensivmed Notfallmed Schmerzther 37:8-15. 2002
    ..Remarkably, DL-intubation in its proper sense then was performed in bronchospirometry only...
  12. ncbi Disturbances in airflow dynamics and tracheal sounds during forced and quiet breathing in subjects with unilateral vocal fold paralysis
    A Saarinen
    Lohja Hospital, Lohja, Finland
    Clin Physiol 21:712-7. 2001
    ..02). According to the present study, both quiet breathing and forced inspiration are disturbed in subjects with unilateral vocal fold paralysis. A close relationship between tracheal sounds and respiratory function tests exists...
  13. ncbi Spontaneous pneumothorax: pragmatic management and long-term outcome
    J M Vernejoux
    Service des Maladies Respiratoires, Hopital du Haut leveque, CHU Bordeaux, France
    Respir Med 95:857-62. 2001
    ..3+/-8.4 months). FHR cases were more frequent in the Pleurocatheter group (P < 0 04). Analysis of potential risk factors showed that the patient's height and a previous homolateral SP episode are independent recurrence risk factors...
  14. ncbi Effect of inhaled budesonide therapy on lung function in schoolchildren born preterm
    A S Pelkonen
    Department of Allergic Diseases, Helsinki University Central Hospital, Finland
    Respir Med 95:565-70. 2001
    ..According to the present study, inhaled budesonide for 4 months had no significant effect on basic lung function but may decrease bronchial lability in schoolchildren born preterm...
  15. ncbi Use of pocket-sized turbine spirometer in monitoring exercise-induced bronchospasm and bronchodilator responses in children
    S Kannisto
    Department of Paediatrics, Kuopio University Hospital, Finland
    Pediatr Allergy Immunol 10:266-71. 1999
    ..However, the turbine spirometer offers the possibility to measure FEV1 repeatedly in field conditions, such as during exercise challenges outdoors...
  16. ncbi Comparison of incremental and bolus dose inhaled allergen challenge in asthmatic patients
    D A Taylor
    Royal Brompton Clinical Studies Unit, Department of Thoracic Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, UK
    Clin Exp Allergy 30:56-63. 2000
    ..Once defined, subsequent challenges are often administered as a constant dose based on the dose from the screening challenge. Previously, constant dose challenges have been employed but never validated...
  17. ncbi Tidal breathing parameters in young children: comparison of measurement by respiratory inductance plethysmography to a facemask pneumotachograph system
    T Manczur
    Departments of Child Health and Thoracic Medicine, King s College Hospital, London, UK
    Pediatr Pulmonol 28:436-41. 1999
    ..The results obtained using the two devices are not interchangeable...
  18. ncbi Immunological parameters and respiratory functions in patients suffering from atopic bronchial asthma after intravenous treatment with salmon calcitonin
    H Kawalski
    Department of Microbiology and Immunology, Silesian School of Medicine, Zabrze Rokitnica, Poland
    Immunol Lett 70:15-9. 1999
    ..Calcitonin at a dose of 100 IU/day subcutaneously for 3 days did not alter the immune parameters studied, thus rendering it safe for such and similar treatment schedules in a variety of medical conditions...
  19. ncbi Beta2-ADR haplotypes/polymorphisms associate with bronchodilator response and total IgE in grass allergy
    G Woszczek
    Department of Clinical Immunology and Allergy, Medical University of Lodz, Lodz, Poland
    Allergy 60:1412-7. 2005
    ..No significant associations were found in regards to asthmatic phenotype and atopy. These results indicate that depending on phenotype studied, either an individual beta2-ADR SNP or beta2-ADR haplotype might affect disease manifestation...
  20. ncbi Inhalation injury after capsaicin exposure
    James Jason Miller
    Department of Physical Medicine and Rehabilitation, University of Louisville School of Medicine and the Frazier Rehab Institute, KY, USA
    J Ky Med Assoc 104:103-5. 2006
    ..Nationwide there have been numerous reports of pepper spray-related injuries, including officers injured in pepper spray-related training exercises. This report details one officer's experience...
  21. ncbi Technical and functional assessment of 10 office spirometers: A multicenter comparative study
    Giuseppe Liistro
    Pneumology Unit, Cliniques Universitaires Saint Luc, Avenue Hippocrate 10, 1200 Bruxelles, Belgium
    Chest 130:657-65. 2006
    ..To investigate the technical properties and user friendliness of 10 office spirometers devoted for use in general practice, and to compare the results with standard diagnostic spirometers...
  22. pmc Associations of dairy intake with CT lung density and lung function
    Rui Jiang
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Am Coll Nutr 29:494-502. 2010
    ..However, the overall associations of dairy intake with lung density and lung function have not been studied...
  23. ncbi [Hepato-pulmonary syndrome]
    Laura Bozomitu
    Clinica a V a Pediatrie, Universitatea de Medicină şi Farmacie Gr T Popa Iaşi Facultatea de Medicină
    Rev Med Chir Soc Med Nat Iasi 114:625-32. 2010
    ..Combined determination of SaO2 in clino- and orthostatic position by a pulsoximeter is a simple test for HPS identification in patients with chronic liver disease or non-cirrhotic portal hypertension...
  24. ncbi Continuous assessment of nasal airflow resistance by adaptive modeling
    T Seppanen
    Department of Electrical and Information Engineering, University of Oulu, Oulu, Finland
    Physiol Meas 30:1197-209. 2009
    ....
  25. doi Effects of exercise training and montelukast in children with mild asthma
    Maria R Bonsignore
    Department of Medicine, Pneumology, Physiology and Nutrition, University of Palermo, Italy
    Med Sci Sports Exerc 40:405-12. 2008
    ....
  26. ncbi Status of lipid peroxidation and plasma iron level in bronchial asthmatic patients
    M K Narula
    Department of Physiology, Dayanand Medical College and Hospital, Ludhiana
    Indian J Physiol Pharmacol 51:289-92. 2007
    ..A positive correlation between plasma MDA and iron (r = +0.3) has been found in asthmatic patients. An increased plasma iron levels in asthmatics may contribute to aggravate lipid peroxidation...
  27. ncbi There are no excuses for not performing spirometry in acute asthmatics in the emergency department setting
    Gustavo J Rodrigo
    Chest 131:1615. 2007
  28. ncbi Spirometer calibration checks: is 3.5% good enough?
    Meredith C McCormack
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 1830 East Monument Street, Baltimore, MD 21205, USA
    Chest 131:1486-93. 2007
    ..5% of the inserted volume but do not require evaluation of trends over time. We examined the current guidelines and candidate quality control rules to determine the best method for identifying spirometers with suboptimal performance...
  29. ncbi Peak expiratory flow is not a quality indicator for spirometry: peak expiratory flow variability and FEV1 are poorly correlated in an elderly population
    Matthew J Hegewald
    Division of Pulmonary and Critical Care Medicine, University of Utah and LDS Hospital, Eighth Ave and C Street, Salt Lake City, UT 84143, USA
    Chest 131:1494-9. 2007
    ..We tested the premise that within-test variability in PEF is associated with corresponding variability in FEV(1) during a single test session...
  30. ncbi Sensitization to Ascaris lumbricoides and severity of childhood asthma in Costa Rica
    Gary M Hunninghake
    Channing Laboratory, Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Allergy Clin Immunol 119:654-61. 2007
    ..Little is known about sensitization (defined as a positive IgE) to helminths and disease severity in patients with asthma...
  31. ncbi Inhaled steroids are associated with reduced lung function decline in subjects with asthma with elevated total IgE
    Roberto de Marco
    University of Verona, Department of Medicine and Public Health, Unit of Epidemiology and Medical Statistics, Verona, Italy
    J Allergy Clin Immunol 119:611-7. 2007
    ..Few studies have investigated the long-term association between inhaled corticosteroids (ICSs) and lung function decline in asthma...
  32. ncbi Air trapping in mild and moderate asthma: effect of inhaled corticosteroids
    José Manuel Tunon-de-Lara
    Universite Bordeaux 2, Institut National de la Santé et de la Recherche Medicale U885, Centre Hospitalier Universitaire CHU de Bordeaux, F 33076 Bordeaux, France
    J Allergy Clin Immunol 119:583-90. 2007
    ..Hydrofluoroalkane-beclomethasone dipropionate (HFA-BDP) is deposited across all sizes of airways, including the small ones. However, its long-term effect on air trapping remains unknown in uncontrolled asthma...
  33. ncbi Adiposity, asthma, and airway inflammation
    Christene R McLachlan
    Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    J Allergy Clin Immunol 119:634-9. 2007
    ..One possible explanation might be that these studies have used body mass index to identify adiposity, which might be a less reliable measure of body fat in men than in women...
  34. ncbi Small airways response to naturalistic cat allergen exposure in subjects with asthma
    Michelle R Zeidler
    Division of Pulmonary, David Geffen School of Medicine and Allergy Research Foundation, University of California, Los Angeles, CA 90025, USA
    J Allergy Clin Immunol 118:1075-81. 2006
    ..It is currently unclear whether the small airways (diameter <2 microm) contribute significantly to late asthmatic reactions to inhaled allergen...
  35. ncbi Contribution of ipratropium bromide to the bronchodilator test in patients with chronic obstructive pulmonary disease
    M Rodriguez-Carballeira
    Department of Internal Medicine, Hospital Mutua de Terrassa, Barcelona, Spain
    Pulm Pharmacol Ther 12:43-8. 1999
    ..01). We conclude that the BDT was positive with high doses of IB in more than half of COPD patients who did not respond to terbutaline alone...
  36. ncbi A simple "step-test" protocol for identifying suspected unrecognized exercise-induced asthma (EIA) in children
    R A Feinstein
    Department of Pediatrics, School of Medicine, University of Alabama at Birmingham, USA
    Allergy Asthma Proc 20:181-8. 1999
    ..In conclusion, a simple, reproducible school-based exercise protocol can be used to identify students with suspected undiagnosed asthma...
  37. ncbi Chronic respiratory disorders related to farming and exposure to grain dust in a rural adult community
    J Manfreda
    Department of Medicine, University of Manitoba, Canada
    Am J Ind Med 15:7-19. 1989
    ..Lung function of former farmers might have been affected by farming, and this may reflect more involvement with livestock in the past...
  38. ncbi Studies of neutrophil chemotactic factor of anaphylaxis in metabisulfite sensitivity
    J D Sprenger
    Department of Medicine, University of Washington School of Medicine, Seattle
    Ann Allergy 62:117-21. 1989
    ..We conclude that sensitivity to aqueous metabisulfite is not associated with mast cell degranulation in metabisulfite skin test-negative patients...
  39. ncbi A Canadian multicenter study with Zaditen (ketotifen) in the treatment of bronchial asthma in children aged 5 to 17 years
    A Rackham
    Clinical Research Department, Sandoz Canada Inc, Dorval, Quebec
    J Allergy Clin Immunol 84:286-96. 1989
    ..No unexpected side effects were observed. It is concluded that Zaditen is an effective medication for long-term control of asthma in children...
  40. ncbi CO2 sensitivity changes during the menstrual cycle
    K Dutton
    Department of Human Movement and Recreation Studies, University of Western Australia, Nedlands
    J Appl Physiol (1985) 67:517-22. 1989
    ..The change between follicular and luteal phases was attributed to the effect of progesterone, which is elevated during the luteal phase. No significant change was found in the CO2 threshold level...
  41. ncbi [Spirographic studies and measurement of airflow resistance in evaluation of bronchial hyperreactivity in children with asthma]
    T Latos
    Specjalistycznego Zespołu Gruźlicy i Chorób Płuc Dzieci w Karpaczu
    Pneumonol Pol 58:107-11. 1990
    ..42 kPa/l/s to 0.63 kpa/l/s. that is by 50%. Both tests spirometric and airflow resistance proved to be comparable in 70.4%. Usage of both methods allows a better chance of diagnosing bronchial hyperreactivity...
  42. ncbi [Analysis of respiratory parameters before and after working in manual laborers at a tobacco factory]
    E Kolarzyk
    Katedra Medycyny Pracy, Chorób Zawodowych AM w Krakowie, Kierownik
    Pneumonol Pol 58:298-306. 1990
    ..This finding concerned mostly workers who inhaled dust of tobacco leaves prior to fermentation...
  43. ncbi [Peak flow measurement]
    P O Willroth
    Bezirkslungenklinik des Bezirkskrankenhauses Schwerin DDR
    Z Erkr Atmungsorgane 174:73-9. 1990
    ..Peak flow rate measurements with a simple device are useful in detecting and objective assessment of obstructive airway disease. They are easy to perform and offer a rational basis for antiobstructive treatment...
  44. ncbi [Electronic spirometry]
    P O Willroth
    Bezirkslungenklinik Schwerin, DDR
    Z Erkr Atmungsorgane 174:7-17. 1990
    ..Electronic spirometry on the basis of forced expiration and flow-volume-curve possess many advantages for the detection of ventilatory alterations in human lung...
  45. pmc The biphasic spirogram: a clue to unilateral narrowing of a mainstem bronchus
    A D Gascoigne
    Department of Respiratory Medicine, Freeman Hospital, Newcastle upon Tyne
    Thorax 45:637-8. 1990
    ..In one patient relief of the bronchial stenosis by the insertion of a stent restored normal contours to the spirogram and flow-volume curves...
  46. ncbi [Potentiating effect of spirometric maneuver on bronchial responsiveness to methacholine in asthmatic subjects--the role of deep inspiration and forced expiration]
    Y Kamio
    Central Clinical Laboratory, Kanazawa University Hospital
    Rinsho Byori 38:1378-82. 1990
    ..51) to 0.16 mg/ml (GSEM, 1.45) and 0.14 mg/ml (GSEM, 1.51) by SM and DI, respectively but it was not altered by FE. These findings indicate that potentiating effect of SM on BR which is characteristic of asthma may be due to DI effect...
  47. ncbi [Histamine provocation test in children]
    H Lindemann
    Selbständiger Funktionsbereich für Pädiatrische Pneumologie und Allergologie, Universitätskinderklinik Giessen
    Pneumologie 45:695-9. 1991
    ..In school-children a bronchial hyperreactivity is established, if a bronchoconstriction occurs below a histamine concentration of less than or equal to 1000 mg/ml...
  48. ncbi Analysis of respiratory impedance characteristics in chronic bronchitis
    G J Wesseling
    Department of Pulmonary Diseases, University Hospital, Maastricht, The Netherlands
    Respiration 59:81-8. 1992
    ....
  49. ncbi Inspiratory spirogram in emphysema
    S Meenakshi
    Madras Medical College
    J Indian Med Assoc 90:115-6. 1992
    ..Reduction in inspiratory airflow resistance following inhalation of bronchodilator giving the most consistent and significant changes in emphysematous patients has been demonstrated in the present study...
  50. ncbi [Effect of misoprostol, a synthetic equivalent of prostaglandin E1, on bronchodilation in bronchial spasm]
    C Marcisz
    IV Katedry i Kliniki Chorób Wewnetrznych Slaskiem AM, Tychach
    Pol Tyg Lek 47:733-4. 1992
    ..However, this activity is rather weak and significantly lower than that of intravenous aminophylline infusion...
  51. ncbi [Health effects of chronic exposure to tobacco smoke on a non-smoker population]
    A M Laurent
    Hopital Cochin, Paris, France
    Rev Pneumol Clin 48:65-70. 1992
    ..In the present state of our knowledge, it is difficult to find evidence of a biological impact, notably on the concentrations of the specific indicators nicotine and cotinine, in subjects passively exposed to tobacco smoke...
  52. ncbi Bronchodilator therapy in cystic fibrosis: for better or worse?
    D Raeburn
    Department of Pharmacology and Experimental Therapeutics, Louisiana State University Medical Center, New Orleans 70112 1393
    Med Hypotheses 26:59-62. 1988
    ..Repeated assessments of respiratory function are necessary and the patient's management must be frequently re-evaluated...
  53. ncbi Obstructive and restrictive ventilatory impairment in polyvinylchloride fabrication workers
    P Ernst
    School of Occupational Health, McGill University, Montreal, Quebec, Canada
    Am J Ind Med 14:273-9. 1988
    ..While the specific exposures have not been identified, it appears that employment in PVC fabrication may be associated with both obstructive and restrictive ventilatory effects...
  54. ncbi [Relation of the fall in PO2 in ventilation of the lower lung in pulmonary surgery and the preoperative distribution of respiratory function]
    M Fischler
    Centre Medico Chirurgical Foch, Suresnes
    Ann Fr Anesth Reanim 7:365-9. 1988
    ..This study aimed to assess whether preoperative selective bronchospirometry could predict the degree of peroperative hypoxaemia...
  55. pmc The acute effects of inhaled salbutamol on the beat-to-beat variability of heart rate and blood pressure assessed by spectral analysis
    T Jartti
    Department of Paediatrics, Turku University Hospital, Finland
    Br J Clin Pharmacol 43:421-8. 1997
    ..We wanted to study the effects of a 600 micrograms inhaled salbutamol dose on the cardiovascular and respiratory autonomic nervous regulation in eight children suffering from bronchial asthma...
  56. pmc Significance of IL-1beta and IL-1 receptor antagonist (IL-1Ra) in bronchoalveolar lavage fluid (BALF) in patients with diffuse panbronchiolitis (DPB)
    J Kadota
    Second Department of Internal Medicine, Nagasaki University School of Medicine, Japan
    Clin Exp Immunol 103:461-6. 1996
    ....
  57. ncbi Changing patterns of aerosol deposition during methacholine bronchoprovocation
    T G O'Riordan
    Department of Medicine, State University of New York, Stony Brook 11794 8172
    Chest 103:1385-9. 1993
    ..Preferential deposition in central airways occurs in all subjects during bronchoprovocation testing and does not significantly determine methacholine responsiveness...
  58. ncbi [Bronchial provocation tests. Comparison of 2 inhalation methods]
    M Badier
    Laboratoire de Physiologie Respiratoire, Faculte de Medecine, Marseille
    Presse Med 22:1169-74. 1993
    ..The dosimeter method had greater efficacy, was less time consuming and appeared to be a useful method for carrying out standardised non-specific bronchoprovocation test...
  59. pmc Stepwise health surveillance for bronchial irritability syndrome in workers at risk of occupational respiratory disease
    W K Post
    Erasmus University, Department of Public Health, Rotterdam, The Netherlands
    Occup Environ Med 55:119-25. 1998
    ..However, the diagnostic performance of these tests is often poor. Application of these tests in a stepwise manner would presumably result in a better characterisation of subjects with respiratory disease...
  60. ncbi Continuous spirometry for detection of double-lumen endobronchial tube displacement
    G I Bardoczky
    Department of Anaesthesiology and Thoracic Surgery, Erasme University Hospital, Free University of Brussels, Belgium
    Br J Anaesth 70:499-502. 1993
    ..Continuous spirometric monitoring is helpful in detecting endobronchial tube displacement during intubation and surgery...
  61. ncbi Progression of chronic obstructive pulmonary disease after multiple episodes of an occupational inhalation fever
    S N Kales
    Harvard School of Public Health, Cambridge, Massachusetts
    J Occup Med 36:75-8. 1994
    ..We believe that this case provides further evidence that polymer fume fever is not always a benign, self-limited illness, especially when workers suffer multiple episodes and/or have underlying pulmonary disease...
  62. ncbi Respiratory health status in swine producers relates to endotoxin exposure in the presence of low dust levels
    J E Zejda
    Centre for Agricultural Medicine, University of Saskatchewan, Saskatoon, Canada
    J Occup Med 36:49-56. 1994
    ..01). These data suggest that respiratory health status relates to endotoxin levels but not to dust level exposures in the presence of low dust levels and indicates that control measures should include endotoxin as well as dust control...
  63. ncbi No effect of the oral neutral endopeptidase inhibitor candoxatril, on bronchomotor tone and histamine reactivity in asthma
    R M Angus
    Dept of Respiratory Medicine, Western Infirmary, Glasgow, UK
    Eur Respir J 7:1084-9. 1994
    ..17 (0.25-25.8) and 0.93 (0.13-32) mg.ml-1, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)..
  64. ncbi Evaluation of an electronic hand-held spirometer in patients with asthma
    S Hamid
    Guy s Hospital, London, U K
    Respir Med 92:1177-80. 1998
    ..2% of all recordings. Twenty-two patients performed valid tests for 80-100% of the time. We suggest that the use of an electronic meter in the home environment is practical and is likely to generate more accurate and reliable data...
  65. ncbi [Preoperative evaluation of the patient candidate for surgical intervention on the chest: methods of study and risk factors]
    M Ferrari
    Universita degli Studi di Verona, Istituto di Clinica Medica Generale e Terapia Medica
    Chir Ital 39:242-57. 1987
    ..The author's experience with fractional bronchospirometry revealed that, in the high-risk patient sample, a predicted postoperative FEV1 value of only 800 ml/sec is a ..
  66. ncbi Inhalation challenge
    R R Rosenthal
    Johns Hopkins University School of Medicine, Baltimore, Maryland
    N Engl Reg Allergy Proc 9:113-22. 1988
    ..Other applications include the evaluation of antigen sensitivity for diagnostic and research purposes including occupational asthma, epidemiology, and investigational drug trials...
  67. ncbi [Does common asthma show intercritical functional anomalies?]
    D Charpin
    Service de Pneumologie, Hopital Sainte Marguerite, Marseille
    Rev Pneumol Clin 44:266-8. 1988
    ....
  68. ncbi Nebulized glucagon in the treatment of bronchospasm in asthmatic patients
    S W Melanson
    Emergency Medicine Residency of the Lehigh Valley, St Luke s Hospital, Bethelehem, PA 18015, USA
    Am J Emerg Med 16:272-5. 1998
    ..05). No adverse effects of glucagon treatment occurred. This study suggests that nebulized glucagon reduces methacholine-induced bronchospasm in asthmatic patients...
  69. ncbi A device for sampling of human alveolar breath for the measurement of expired volatile organic compounds
    J H Raymer
    Analytical and Chemical Sciences, Research Triangle Institute, North Carolina 27709
    J Anal Toxicol 14:337-44. 1990
    ..e., adsorption carryover by the device) was measured at the 50-micrograms/m3 level. The data suggest that the device can be used successfully for organic compounds with volatilities greater than that of p-dichlorobenzene...
  70. ncbi [Response to bronchodilators among patients with bronchial asthma]
    S Quadrelli
    Instituto de Investigaciones Medicas Alfredo Lanari, Facultad de Medicina, Universidad de Buenos Aires, Argentina
    Medicina (B Aires) 54:311-8. 1994
    ..twelve of which (4% of the whole) showed delta% > 15% (initial FEVI 0.81 +/- 0.171) (Table 2).(ABSTRACT TRUNCATED AT 250 WORDS)..
  71. ncbi The local prevalence of COPD by post-bronchodilator GOLD criteria in Korea
    S J Kim
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 425 707, Republic of Korea
    Int J Tuberc Lung Dis 10:1393-8. 2006
    ..We aimed to examine the prevalence and risk factors of COPD in Ansan, an industrialised city of Korea, by using the post-bronchodilator GOLD criteria. We then investigated the implications of brenchodilation on the prevalence of COPD...

Research Grants3

  1. MECHANISM(S) OF HYPERPNEA ELICITED BY CO2 INHALATION
    HUBERT FORSTER; Fiscal Year: 1980
    ..In year 2, we will also study a second group of ponies in which, through chronic traceostomy and acute bronchospirometry, we can investigate the effect on VE and respiratory timing of altering (CO2) in selective portions of ..
  2. Diet, Biomarkers and Lung Function
    Rui Jiang; Fiscal Year: 2008
    ..This proposal will prepare the candidate well to apply successfully for R01 on diet, diet-related genes, and gene-diet interactions in lung function and COPD. ..
  3. The Impact of Indoor Particulate Matter Exposure on Non-Allergic Asthma
    MEREDITH MCCORMACK; Fiscal Year: 2008
    ....