- Effects of size and temperature on metabolic rate
J F Gillooly
Department of Biology, The University of New Mexico, Albuquerque, NM 87131, USA
Science 293:2248-51. 2001
..Temperature and body size are primary determinants of biological time and ecological roles...
- Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
, Sciences II, , CH-1211 Geneva, Switzerland
Genes Dev 14:2950-61. 2000
..Food-induced phase resetting proceeds faster in liver than in kidney, heart, or pancreas, but after 1 wk of daytime feeding, the phases of circadian gene expression are similar in all examined peripheral tissues...
- Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators
Department of Molecular Biology, National Centers of Competence in Research Frontiers in Genetics, Sciences III, University of Geneva, CH 1211 Geneva 4, Switzerland
Genes Dev 26:567-80. 2012
..Here, we investigated the role of daily body temperature fluctuations as possible systemic cues in the resetting of peripheral oscillators...
- Mammalian hibernation: cellular and molecular responses to depressed metabolism and low temperature
Hannah V Carey
Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
Physiol Rev 83:1153-81. 2003
..The hibernation season is characterized by extended bouts of torpor, during which minimal body temperature (Tb) can fall as low as -2.9 degrees C and metabolism can be reduced to 1% of euthermic rates...
- Rhythms of mammalian body temperature can sustain peripheral circadian clocks
Steven A Brown
Department of Molecular Biology, University of Geneva, Sciences II, 30, Quai Ernest Ansermet, CH 1211 Geneva, Switzerland
Curr Biol 12:1574-83. 2002
..Because mammalian body temperature is subject to circadian variations of 1 degrees C-4 degrees C, we wished to determine whether these ..
- Towards a molecular understanding of adaptive thermogenesis
B B Lowell
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
Nature 404:652-60. 2000
..Here we explore these developments in relation to classical physiological views of adaptive thermogenesis...
- Hyperthermia and central fatigue during prolonged exercise in humans
Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, DK 2200 Copenhagen Ø, Denmark
J Appl Physiol (1985) 91:1055-60. 2001
..In conclusion, these data demonstrate that the ability to generate force during a prolonged MVC is attenuated with hyperthermia, and the impaired performance is associated with a reduction in the voluntary activation percentage...
- Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease
Department of Biochemistry, Trinity College Institute of Neuroscience, Trinity College Dublin, Republic of Ireland
Biol Psychiatry 65:304-12. 2009
- Changes in hypothalamic-pituitary-adrenal function, body temperature, body weight and food intake with repeated social stress exposure in rats
Department of Anaesthesiology, Abranson Building Ste 402, Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
J Neuroendocrinol 18:13-24. 2006
These present studies aimed to compare changes in hypothalamic-pituitary-adrenal (HPA) activity and body temperature in response to acute social defeat, to repeated social stress and to novel restraint after repeated stress, as well as to ..
- Long-term calorie restriction, but not endurance exercise, lowers core body temperature in humans
Division of Geriatrics and Nutritional Sciences and Center for Human Nutrition, Washington University School of Medicine, St Louis, Missouri, USA
Aging (Albany NY) 3:374-9. 2011
Reduction of body temperature has been proposed to contribute to the increased lifespan in calorie restricted animals and mice overexpressing the uncoupling protein-2 in hypocretin neurons...
- Measurement of brain temperature with magnetic resonance spectroscopy in acute ischemic stroke
Department of Neurology of Adults, Medical University of Gdansk, Gdansk, Poland
Ann Neurol 60:438-46. 2006
..We used magnetic resonance spectroscopic imaging (water-to-N-acetylaspartate frequency shift) to measure cerebral temperature noninvasively in stroke patients...
- Guidelines for evaluation of new fever in critically ill adult patients: 2008 update from the American College of Critical Care Medicine and the Infectious Diseases Society of America
NAOMI P O'GRADY
National Institutes of Health, Bethesda, MD, USA
Crit Care Med 36:1330-49. 2008
..To update the practice parameters for the evaluation of adult patients who develop a new fever in the intensive care unit, for the purpose of guiding clinical practice...
- Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals
Department of Neuroanatomy, Paul Flechsig Institute of Brain Research, University of Leipzig, D 04109 Leipzig, Germany
J Neurosci 23:6972-81. 2003
..Hibernation will, therefore, be a valuable model to study the regulation of PHF-like tau-phosphorylation and its cell biological sequelae under physiological in vivo conditions...
- A phase response curve to single bright light pulses in human subjects
Sat Bir S Khalsa
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Physiol 549:945-52. 2003
..02 h. Phase delays occurred when the light stimulus was centred prior to the critical phase at the core body temperature minimum, phase advances occurred when the light stimulus was centred after the critical phase, and no phase ..
- Emerging disease of amphibians cured by elevated body temperature
Douglas C Woodhams
School of Tropical Biology, James Cook University, Townsville, Queensland 4811, Australia
Dis Aquat Organ 55:65-7. 2003
- Three-dimensional cryoEM reconstruction of native LDL particles to 16Å resolution at physiological body temperature
Department of Biomedical Engineering and Computational Science, School of Science and Technology, Centre of Excellence in Computational Complex Systems Research, Aalto University Aalto, Finland
PLoS ONE 6:e18841. 2011
..The shape of native LDL particles and the conformation of native apoB-100 on the particles remain incompletely characterized at the physiological human body temperature (37 °C).
- betaAR signaling required for diet-induced thermogenesis and obesity resistance
Eric S Bachman
Department of Medicine, Division of Endocrinology, Beth Israel Deaconess Medical Center and Harvard Medical School, 99 Brookline Avenue, Boston, MA 02215, USA
Science 297:843-5. 2002
..These findings establish that betaARs are necessary for diet-induced thermogenesis and that this efferent pathway plays a critical role in the body's defense against diet-induced obesity...
- Target Temperature Management after out-of-hospital cardiac arrest--a randomized, parallel-group, assessor-blinded clinical trial--rationale and design
Department of Anesthesia and Intensive Care, Helsingborg Hospital, Helsingborg, Sweden
Am Heart J 163:541-8. 2012
..Previous trials were small, with high risk of bias, evaluated select populations, and did not treat hyperthermia in the control groups. The optimal target temperature management strategy is not known...
- Core body temperature during competition in the heat: National Boys' 14s Junior Championships
Michael F Bergeron
Environmental Physiology Laboratory, Medical College of Georgia, Augusta, Georgia 30912, USA
Br J Sports Med 41:779-83. 2007
To examine on-court core body temperature (T(C)) and sweat loss, as well as pre- and post-play hydration status, in elite adolescent tennis players during a national championships event in a hot climate.
- Microsatellite mapping of QTL affecting growth, feed consumption, egg production, tonic immobility and body temperature of Japanese quail
Génétique et Diversité Animales, Institut National de la Recherche Agronomique, Centre de Jouy, 78352 Jouy en Josas, France
BMC Genomics 6:87. 2005
- Effect of restraint and injection methods on heart rate and body temperature in mice
M K Meijer
Department of Animals, Science and Society, Utrecht University, Utrecht, The Netherlands
Lab Anim 40:382-91. 2006
..to gain more insight into quantifying this acute stress by means of the parameters heart rate (HR) and body temperature (BT), we subjected mice to different restraint and injection methods...
- Prenatal exposure to elevated maternal body temperature and risk of epilepsy in childhood: a population-based pregnancy cohort study
Department of Epidemiology, University of Aarhus, Aarhus, Denmark
Paediatr Perinat Epidemiol 25:53-9. 2011
Elevated maternal body temperature during pregnancy is of clinical concern as side effects have been reported. We estimated the association between maternal fever and sauna bathing during pregnancy and risk of epilepsy in the offspring...
- Inverse relationship of baseline body temperature and outcome between ischemic stroke patients treated and not treated with thrombolysis: the Bergen stroke study
Department of Neurology, Haukeland University Hospital, University of Bergen, Bergen, Norway
Acta Neurol Scand 122:414-7. 2010
High body temperature may promote clot lysis whereas low body temperature is neuroprotective in patients with cerebral infarction...
- Maximal heat dissipation capacity and hyperthermia risk: neglected key factors in the ecology of endotherms
John R Speakman
Institute of Biological and Environmental Sciences, University of Aberdeen, Tillydrone Avenue 2, Aberdeen, Scotland, UK
J Anim Ecol 79:726-46. 2010
- Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation
Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL, USA
Pain 152:1165-72. 2011
Despite the increasing interest in TRPA1 channel as a pain target, its role in cold sensation and body temperature regulation is not clear; the efficacy and particularly side effects resulting from channel blockade remain poorly ..
- Impact of the human circadian system, exercise, and their interaction on cardiovascular function
Frank A J L Scheer
Division of Sleep Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 107:20541-6. 2010
- Adaptive mechanisms regulate preferred utilization of ketones in the heart and brain of a hibernating mammal during arousal from torpor
Matthew T Andrews
Department of Biology, University of Minnesota Duluth, Duluth, Minnesota 1035 Kirby Dr, Duluth, MN 55812, USA
Am J Physiol Regul Integr Comp Physiol 296:R383-93. 2009
..We show that BHB and glucose enter the heart and brain under conditions of depressed body temperature and heart rate but that their utilization as a fuel is highly selective...
- Hibernation in black bears: independence of metabolic suppression from body temperature
Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK 99775, USA
Science 331:906-9. 2011
..We measured metabolic rate and body temperature in hibernating black bears and found that they suppress metabolism to 25% of basal rates while regulating ..
- Permeability of the blood-brain barrier depends on brain temperature
E A Kiyatkin
Behavioral Neuroscience Branch, National Institute on Drug Abuse Intramural Research Program, NIH, Baltimore, MD 21224, USA
Neuroscience 161:926-39. 2009
..Therefore, brain temperature per se is an important factor in regulating BBB permeability, alterations in brain water homeostasis, and subsequent structural abnormalities of brain cells...
- The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation
Jens T Stieler
Department of Molecular and Cellular Mechanisms of Neurodegeneration, Paul Flechsig Institute of Brain Research, University of Leipzig, Leipzig, Germany
PLoS ONE 6:e14530. 2011
..hibernation characteristics of black bears with a continuous torpor period and an only slightly decreased body temperature, therefore, potentially reflects the limitations of this adaptive reaction pattern and, thus, might indicate ..
- Body temperature and its effect on leukocyte mobilization, cytokines and markers of neutrophil activation during and after exercise
School of Human Movement Studies, University of Queensland, Brisbane, QLD, 4072, Australia
Eur J Appl Physiol 102:391-401. 2008
- Body temperature modulates the antioxidant and acute immune responses to exercise
Laboratory of Physical Activity Science, Department of Fundamental Biology and Health Sciences, University of the Balearic Islands, Palma de Mallorca, Spain
Free Radic Res 46:799-808. 2012
..In conclusion, the increased core body temperature results in the acute phase immune response associated to intense exercise and in the immune cell adaptations ..
- Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature
M Camila Almeida
Systemic Inflammation Laboratory FeverLab, Trauma Research, St Joseph s Hospital and Medical Center, Phoenix, Arizona 85013, USA
J Neurosci 32:2086-99. 2012
..In vivo, M8-B decreased deep body temperature (T(b)) in Trpm8(+/+) mice and rats, but not in Trpm8(-/-) mice, thus suggesting an on-target action...
- Season primes the brain in an arctic hibernator to facilitate entrance into torpor mediated by adenosine A(1) receptors
Tulasi R Jinka
Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska 99775 7000, USA
J Neurosci 31:10752-8. 2011
Torpor in hibernating mammals defines the nadir in mammalian metabolic demand and body temperature that accommodates seasonal periods of reduced energy availability...
- A thermosensory pathway that controls body temperature
Neurological Sciences Institute, Oregon Health and Science University, Beaverton, OR 97006, USA
Nat Neurosci 11:62-71. 2008
Defending body temperature against environmental thermal challenges is one of the most fundamental homeostatic functions that are governed by the nervous system...
- Influence of hydration on physiological function and performance during trail running in the heat
Douglas J Casa
Department of Kinesiology, University of Connecticut, Storrs, CT 06269 1110, USA
J Athl Train 45:147-56. 2010
..Investigators in these field studies did not control exercise intensity, a known modulator of body core temperature...
- The mammalian circadian timing system: synchronization of peripheral clocks
Department of Molecular Biology and National CCR Frontiers in Genetics, Sciences III, University of Geneva, 1211 Geneva 4, Switzerland
Cold Spring Harb Symp Quant Biol 76:39-47. 2011
- Does basal metabolic rate contain a useful signal? Mammalian BMR allometry and correlations with a selection of physiological, ecological, and life-history variables
Craig R White
Department of Environmental Biology, School of Earth and Environmental Sciences, University of Adelaide, Adelaide, South Australia 5005, Australia
Physiol Biochem Zool 77:929-41. 2004
..of the relationship between mammalian body mass (M, g) and BMR that accounts for variation associated with body temperature, digestive state, and phylogeny...
- Circadian temperature and melatonin rhythms, sleep, and neurobehavioral function in humans living on a 20-h day
J K Wyatt
Circadian, Neuroendocrine and Sleep Disorders Section, Division of Endocrinology, Department of Medicine, Brigham and Women s Hospital Harvard Medical School, Boston, Massachusetts 02115, USA
Am J Physiol 277:R1152-63. 1999
..20-h rest/activity cycle, resulting in desynchrony between the sleep-wake cycle and the circadian rhythms of body temperature and melatonin...
- Effects of dietary resveratrol on the sleep-wake cycle in the non-human primate gray mouse lemur (Microcebus murinus)
UMR CNRS MNHN 7179, Brunoy, France
Chronobiol Int 29:261-70. 2012
..The present data suggest that RSV may be a potent regulator of sleep-wake rhythms and could be of major interest in the study of sleep perturbations associated with aging and neuropathology...
- Hyperthermia impairs short-term memory and peripheral motor drive transmission
ASPETAR, Qatar Orthopaedic and Sports Medicine Hospital, Exercise and Sports Science Department, Doha, Qatar
J Physiol 586:4751-62. 2008
..The decrement in memory capacity suggested the existence of frontal lobe activity impairments. Thus, HHC preserved memory capacity but not the visual memory...
- Hemoglobin senses body temperature
G M Artmann
Division Juelich, Aachen University of Applied Sciences, Juelich, Germany
Eur Biophys J 38:589-600. 2009
..In NMR T(1)-relaxation time measurements, the T(1) of RBCs in autologous plasma changed from a linear (r = 0.99) increment below T(c) = 37 +/- 1 degrees C at a rate of 0.023 s/K into zero slope above T(c) (RBC T(1) transition)...
- Fever detection in under 5 children in a tertiary health facility using the infrared tympanic thermometer in the oral mode
Benedict O Edelu
Department of Pediatrics, University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu, Nigeria
Ital J Pediatr 37:8. 2011
Monitoring of body temperature is an important clinical procedure in the care of sick children, especially the under-5 children, as many disease conditions present with fever...
- Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
Laboratory of Genetics, National Institute of Mental Health, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 96:5780-5. 1999
..Thus, most, but not all, CNS effects of Delta9-THC are mediated by the CB1 receptor...
- Cooling for Acute Ischemic Brain Damage (COOL AID): a feasibility trial of endovascular cooling
M A De Georgia
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Neurology 63:312-7. 2004
..To report results of a randomized pilot clinical feasibility trial of endovascular cooling in patients with ischemic stroke...
- Effects of waking time and breakfast intake prior to evaluation of physical performance in the early morning
Universite de Caen, EA3917, UFR STAPS, Caen, France
Chronobiol Int 26:307-23. 2009
Diurnal variation in both core body temperature and indicators of physical performance are usually observed when measures are taken at 06:00 and 18:00 h...
- Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat
Paul M L Janssen
Institute of Molecular Cardiobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Am J Physiol Heart Circ Physiol 282:H499-507. 2002
..We conclude that temperature independently affects contraction and relaxation, and cross-bridge cycling kinetics become rate limiting for cardiac relaxation under experimental conditions closest to those in vivo...
- The interrelationship between sleep regulation and thermoregulation
Thermophysiological Chronobiology, Centre for Chronobiology, Psychiatric Hospital of the University of Basel, Switzerland
Front Biosci (Landmark Ed) 15:604-25. 2010
The circadian distribution of vigilance states and body temperature changes are tightly coupled. The increase in heat loss at the end of the day is associated with increased ease to fall asleep...
- Aerosol exposure to the angola strain of marburg virus causes lethal viral hemorrhagic Fever in cynomolgus macaques
D A Alves
Center for Vaccine Research, University of Pittsburgh, 8037 BST3, 3051 Fifth Avenue, Pittsburgh, PA 15261, USA
Vet Pathol 47:831-51. 2010
..These macaques exhibited a number of features similar to those of human filovirus infections; as such, this model of aerosolized MARV-Angola might be useful in developing medical countermeasures under the Animal Rule...
- Blood cell dynamics during hibernation in the European Ground Squirrel
H R Bouma
Department of Clinical Pharmacology, Groningen University Institute for Drug Exploration GUIDE, University Medical Center Groningen, The Netherlands
Vet Immunol Immunopathol 136:319-23. 2010
..5h after onset of arousal, even before body temperature is fully normalized.
- Physiology of invasion: cane toads are constrained by thermal effects on physiological mechanisms that support locomotor performance
Integrative Physiology, School of Biological Sciences A08, University of Sydney, NSW 2006, Australia
J Exp Biol 214:1437-44. 2011
..It is likely that human-induced global warming will facilitate invasions of environments that are currently too cool to support cane toads...
- Body temperature and response to thrombolytic therapy in acute ischaemic stroke
Department of Neurosciences, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
Eur J Neurol 15:1384-9. 2008
To determine the relationship between body temperature (BT), arterial recanalization, functional outcome, and hemorrhagic transformation (HT) of cerebral infarction in patients treated with i.v. tissue plasminogen activator (tPA).
- Real-time monitoring of cardiovascular function in rhesus macaques infected with Zaire ebolavirus
Mark G Kortepeter
Department of Preventive Medicine, Infectious Disease Clinical Research Program, Uniformed Services University, Bethesda, MD 20814, USA
J Infect Dis 204:S1000-10. 2011
..This is the first report of continuous physiologic monitoring in filovirus-infected nonhuman primates and the first to attempt cardiovascular support with intravenous fluids...
- Alterations in cognitive performance during passive hyperthermia are task dependent
Research and Education Centre, ASPETAR, Qatar Orthopaedic and Sports Medicine Hospital, Doha, Qatar
Int J Hyperthermia 27:1-9. 2011
- Acute administration of 3,4-methylenedioxymethamphetamine induces profound hyperthermia, blood-brain barrier disruption, brain edema formation, and cell injury
Hari Shanker Sharma
Laboratory of Neurochemistry, Division of Neurotoxicology, National Center of Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, USA
Ann N Y Acad Sci 1139:242-58. 2008
- The ingestible telemetric body core temperature sensor: a review of validity and exercise applications
School of Sport and Health Sciences, St Luke s Campus, University of Exeter, Exeter EX1 2LU, UK
Br J Sports Med 41:126-33. 2007
..It is concluded that the ingestible telemetric temperature sensor represents a valid index of Tc and shows excellent utility for ambulatory field-based applications...
- Cardiovascular function in the heat-stressed human
C G Crandall
Department of Internal Medicine Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, and University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75231, USA
Acta Physiol (Oxf) 199:407-23. 2010
..These alterations in cardiovascular function and regulation late in heat stress/dehydration exercise might involve the interplay of both local and central reflexes, the contribution of which is presently unresolved...
- Natural resistance to liver cold ischemia-reperfusion injury associated with the hibernation phenotype
Susanne L Lindell
Department of Comparative Biosciences, University of Wisconsin, 2015 Linden Dr, Madison WI 53706, USA
Am J Physiol Gastrointest Liver Physiol 288:G473-80. 2005
..Because hibernation-induced protection is not dependent on animals being in the torpid state, the mechanisms responsible for this effect may provide new strategies for liver preservation in humans...
- Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNalpha/beta and IL-1beta responses in the diseased brain and exacerbates chronic neurodegeneration
School of Biochemistry and Immunology, Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
Brain Behav Immun 24:996-1007. 2010
..That systemic poly I:C accelerates neurodegeneration has implications for the control of systemic viral infection during chronic neurodegeneration and indicates that type I interferon responses in the brain merit further study...
- Revisiting spontaneous internal desynchrony using a quantitative model of sleep physiology
Andrew J K Phillips
Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Biol Rhythms 26:441-53. 2011
..Our findings suggest that feedback from behavioral choices to physiology could play an important role in spontaneous internal desynchrony...
- Passive hyperthermia reduces voluntary activation and isometric force production
Human Performance Laboratory, Faculty of Kinesiology, University of New Brunswick, Fredericton, NB, E3B 5A3, Canada
Eur J Appl Physiol 91:729-36. 2004
..05). We conclude that an elevated T(c) reduces VA during isometric MVC, and neither T(sk) nor cardiovascular or psychophysical strain modulates this response. Results are given as mean (SD) unless otherwise stated...
- The suprachiasmatic nucleus participates in food entrainment: a lesion study
Departamento de Anatomia, Fac de Medicina, Universidad Nacional Autonoma de Mexico, Mexico DF
Neuroscience 165:1115-26. 2010
..The present results indicate that the SCN participates actively during food entrainment modulating the response of hypothalamic and corticolimbic structures, resulting in an increased anticipatory response...
- Body temperature variability (Part 1): a review of the history of body temperature and its variability due to site selection, biological rhythms, fitness, and aging
Altern Med Rev 11:278-93. 2006
b>Body temperature is a complex, non-linear data point, subject to many sources of internal and external variation...
- Chronic circadian disturbance by a shortened light-dark cycle increases mortality
Department of Biological Sciences, Seoul National University, Seoul, Korea
Neurobiol Aging 33:1122.e11-22. 2012
..We found that the disturbed rhythms of locomotor activity and body temperature resulted from interaction of endogenous clock and T cycle and the chronic state of the disturbance suppressed ..
- Timing for fever-related brain damage in acute ischemic stroke
Department of Neurology, Complexo Hospitalario Universitario de Santiago Hospital Xeral de Galicia, Barcelona, Spain
Stroke 29:2455-60. 1998
..The aim of this study was to determine the prognostic value of body temperature measured at different times after onset of stroke.
- The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1
J L Teeling
CNS Inflammation Group, School of Biological Sciences, University of Southampton, Bassett Crescent East SO167PX, UK
Brain Behav Immun 24:409-19. 2010
..Changes in body temperature, open-field activity, and burrowing were assessed and mRNA and/or protein levels of inflammatory mediators ..
- Early brain temperature elevation and anaerobic metabolism in human acute ischaemic stroke
Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Rd, Edinburgh, EH4 2XU, UK
Brain 132:955-64. 2009
..Early brain temperature elevation may result from different mechanisms to those which raise body temperature after stroke...
- The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice
Sleep and Performance Research Center, Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, Washington State University, Pullman, WA 99164, USA
Proc Natl Acad Sci U S A 106:14069-74. 2009
..knockout mice enter hypothermic bouts associated with reduced sleep, culminating in a marked drop in body temperature to near-ambient levels...
- Pharmacological interaction between 3,4-methylenedioxymethamphetamine (ecstasy) and paroxetine: pharmacological effects and pharmacokinetics
Pharmacology Research Unit, Institut Municipal d Investigació Mèdica Hospital del Mar, Doctor Aiguader 88, E 08003 Barcelona, Spain
J Pharmacol Exp Ther 323:954-62. 2007
..Marked decrease in the effects of MDMA could lead users to take higher doses of MDMA and to produce potential life-threatening toxic effects...
- Thermoregulation as a sleep signalling system
Saul S Gilbert
Centre for Sleep Research, Level 5, The Basil Hetzel Institute, University of South Australia, The Queen Elizabeth Hospital, Woodville Road, Woodville, SA 5011, Australia
Sleep Med Rev 8:81-93. 2004
Temperature and sleep are interrelated processes. Under normal environmental conditions, the rhythms of core body temperature Tc and sleep propensity vary inversely across the day and night in healthy young adults...
- Thermoregulatory responses to lipopolysaccharide in the mouse: dependence on the dose and ambient temperature
Alla Y Rudaya
Systemic Inflammation Laboratory, Trauma Research, St Joseph s Hospital and Medical Center, 350 W Thomas Rd, Phoenix, Arizona 85013, USA
Am J Physiol Regul Integr Comp Physiol 289:R1244-52. 2005
..The present investigation identifies experimental conditions to study LPS-induced mono-, bi-, and polyphasic fevers and late hypothermia in mice and provides detailed characteristics of these responses...
- Dynamics of frontal EEG activity, sleepiness and body temperature under high and low sleep pressure
Centre for Chronobiology, Psychiatric University Clinic, Wilhelm Kleinstr. 27, CH-4025 Basel, Switzerland
Neuroreport 12:2277-81. 2001
..pressure) vs sleep satiation (low sleep pressure) on waking EEG dynamics, subjective sleepiness and core body temperature (CBT) was investigated in 10 young volunteers in a 40 h controlled constant posture protocol...
- Temperature monitoring and perioperative thermoregulation
Daniel I Sessler
Department of Outcomes Research, The Cleveland Clinic P77, Cleveland, Ohio 44195, USA
Anesthesiology 109:318-38. 2008
..Nonetheless, temperature can be reliably measured in most patients. Body temperature should be measured in patients undergoing general anesthesia exceeding 30 min in duration and in patients ..
- Impaired nociception and pain sensation in mice lacking the capsaicin receptor
M J Caterina
Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94143 0450, USA
Science 288:306-13. 2000
..Thus, VR1 is essential for selective modalities of pain sensation and for tissue injury-induced thermal hyperalgesia...
- The circadian rhythm of core temperature: origin and some implications for exercise performance
Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
Chronobiol Int 22:207-25. 2005
..This interaction is manifest in the initial response to spontaneous activity and to mild exercise, body temperature rising more quickly and thermoregulatory reflexes being recruited less quickly around the trough and rising ..
- Effects of hyperthermia on cerebral blood flow and metabolism during prolonged exercise in humans
Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Denmark
J Appl Physiol 93:58-64. 2002
- Admission body temperature predicts long-term mortality after acute stroke: the Copenhagen Stroke Study
L P Kammersgaard
Department of Neurology, University Hospital Gentofte, Copenhagen, Denmark
Stroke 33:1759-62. 2002
b>Body temperature is considered crucial in the management of acute stroke patients. Recently hypothermia applied as a therapy for stroke has been demonstrated to be feasible and safe in acute stroke patients...
- Behavioral and physiological mouse assays for anxiety: a survey in nine mouse strains
J Adriaan Bouwknecht
Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Behav Brain Res 136:489-501. 2002
..We conclude that a combination of behavioral and physiological responses might lead to a better understanding in anxiety-related processes...
- Induction of muscle thermogenesis by high-fat diet in mice: association with obesity-resistance
Department of Adipose Tissue Biology, Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, Prague, Czech Republic
Am J Physiol Endocrinol Metab 295:E356-67. 2008
- Hibernation and daily torpor minimize mammalian extinctions
Centre for Behavioural and Physiological Ecology, Zoology, University of New England, Armidale, NSW 2351, Australia
Naturwissenschaften 96:1235-40. 2009
..5%) of 61 recently extinct mammal species were homeothermic, maintaining a constant high body temperature and thus energy expenditure, which demands a high intake of food, long foraging times, and thus exposure to ..
- Food-anticipatory circadian rhythms: concepts and methods
Ralph E Mistlberger
Department of Psychology, Simon Fraser University, 8888 University Drive, Burnaby, BC V5A 1S6, Canada
Eur J Neurosci 30:1718-29. 2009
- Elevated expression of protein biosynthesis genes in liver and muscle of hibernating black bears (Ursus americanus)
Vadim B Fedorov
Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska 99775, USA
Physiol Genomics 37:108-18. 2009
- Invited review: aging and human temperature regulation
W Larry Kenney
Noll Physiological Laboratory Research Center, Pennsylvania State University, University Park, PA 16802 6900, USA
J Appl Physiol (1985) 95:2598-603. 2003
- Sex differences in emotional and psychophysiological responses to musical stimuli
Urs M Nater
Institute of Psychology, Clinical Psychology and Psychotherapy, University of Zurich, Switzerland
Int J Psychophysiol 62:300-8. 2006
..Furthermore, our study indicates that the confounding effects of sex differences have to be considered when using musical stimuli for emotion induction...
- A pilot study of rapid cooling by cold saline and endovascular cooling before reperfusion in patients with ST-elevation myocardial infarction
Department of Coronary Heart Disease, Skane University Hospital, Lund University, Lund, Sweden
Circ Cardiovasc Interv 3:400-7. 2010
..We aimed to evaluate the safety and feasibility of rapidly induced hypothermia by infusion of cold saline and endovascular cooling catheter before reperfusion in patients with acute myocardial infarction...
- Circadian pattern of sleep, energy expenditure, and body temperature of young healthy men during the intermittent fasting of Ramadan
The University Sleep Disorders Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia
Appetite 54:426-9. 2010
..delay in the acrophase of skin temperature during Ramadan, indicating a shift in the circadian pattern of body temperature. Additionally, there was a delay in the peak of energy expenditure during R1 and R2...
- Natural hypometabolism during hibernation and daily torpor in mammals
Department of Biology, Philipps University, Karl von Frisch Strasse, D 35032 Marburg, Germany
Respir Physiol Neurobiol 141:317-29. 2004
..b>Body temperature gradually decreases towards the level of ambient temperature...
- Influence of admission body temperature on stroke mortality
Centre for Clinical Epidemiology and Biostatistics, Royal Newcastle Hospital, New South Wales, Australia
Stroke 31:404-9. 2000
The influence of body temperature on stroke outcome remains uncertain...
- Paradoxical resistance to diet-induced obesity in UCP1-deficient mice
Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
J Clin Invest 111:399-407. 2003
..total oxygen consumption and physical activity of mutant and wild-type mice are indistinguishable; however, body temperature is higher in UCP1-deficient mice by 0.1-0.3 degrees C, and respiratory quotient is slightly reduced...
- The stress-induced hyperthermia paradigm as a physiological animal model for anxiety: a review of pharmacological and genetic studies in the mouse
J Adriaan Bouwknecht
Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Neurosci Biobehav Rev 31:41-59. 2007
..The advantages and disadvantages of the SIH procedure as a physiological model of anxiety are discussed...
- Therapeutic hypothermia for acute stroke
Tom Skyhøj Olsen
Stroke Unit, Hvidovre University Hospital, DK 2650, Hvidovre, Denmark
Lancet Neurol 2:410-6. 2003
..b>Body temperature is directly related to stroke severity and outcome, and fever after stroke is associated with substantial ..
- [Aging and biological rhythms in primates]
UMR 5176 CNRS MNHN, Département Ecologie et Gestion de la Biodiversité, 4, avenue du Petit Château, 91800 Brunoy, France
Med Sci (Paris) 22:279-83. 2006
..Aging induces a decrease in amplitude of the body temperature rhythm and an increase in energy consumption...
- Effect of time of day on aerobic contribution to the 30-s Wingate test performance
Research Unit, Evaluation, Sport, Health, National Centre of Medicine and Science in Sport, Route de l Aéroport, Sfax 3000, Tunisia
Chronobiol Int 24:739-48. 2007
..A significant circadian rhythm was found in body temperature with a circadian acrophase at 18:16+/-00:25 h as determined by cosinor analysis...
- The Paracetamol (Acetaminophen) In Stroke (PAIS) trial: a multicentre, randomised, placebo-controlled, phase III trial
Heleen M den Hertog
Department of Neurology, Erasmus MC University Medical Centre, Rotterdam, Netherlands
Lancet Neurol 8:434-40. 2009
High body temperature in the first 12-24 h after stroke onset is associated with poor functional outcome...
- Increased benefit of alteplase in patients with ischemic stroke and a high body temperature
Inger de Ridder
Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
Cerebrovasc Dis 35:60-3. 2013
In observational studies, a high body temperature has been associated with unfavorable outcome. In in vitro studies, the fibrinolytic activity of alteplase decreased 5% per degree Celsius reduction in temperature...
- Sex- and age-specific differences in core body temperature of C57Bl/6 mice
Molecular and Integrative Neurosciences Department, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
Age (Dordr) 33:89-99. 2011
..Thus, gonadal-dependent modulation of Tc may be one of the physiological parameters contributing to gender-specific differences in longevity...
- Association of body temperature and antipyretic treatments with mortality of critically ill patients with and without sepsis: multi-centered prospective observational study
Byung Ho Lee
Department of Anesthesiology, St Paul s Hospital, Catholic University of Korea, Seoul, Republic of Korea
Crit Care 16:R33. 2012
..The association of fever and antipyretics with mortality, however, may be different between infective and non-infective illness...
- Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat
Departament de Bioquimica i Biologia Molecular, Institut de Biomedicina de la Universitat de Barcelona and CIBER Fisiopatologia de la Obesidad y Nutrición, Barcelona, Catalonia, Spain
Cell Metab 11:206-12. 2010
..found that this enhanced the expression of genes involved in thermogenesis within brown fat, and increased body temperature. Brown adipocytes treated with FGF21 exhibited increased expression of thermogenic genes, higher total and ..
- Stroke severity determines body temperature in acute stroke
Department of Neurology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark
Stroke 32:413-7. 2001
..Experimental studies showing that hyperthermia increases infarct size have lent credibility to this assumption. The aim of the present study was to test the hypothesis that initial body temperature is of importance for stroke outcome.
- Effectiveness of resistive heating compared with passive warming in treating hypothermia associated with minor trauma: a randomized trial
Ludwig Boltzmann Institute, University of Vienna, Austria
Mayo Clin Proc 76:369-75. 2001
..Hypothermia is common even in persons with minor trauma. Resistive heating during transport augments thermal comfort, increases core temperature, reduces pain and anxiety, and improves overall patient satisfaction...
- Acute concomitant effects of MDMA binge dosing on extracellular 5-HT, locomotion and body temperature and the long-term effect on novel object discrimination in rats
School of Biomedical Sciences, Medical School, Queen s Medical Centre, University of Nottingham, Nottingham, UK
Psychopharmacology (Berl) 213:365-76. 2011
..3,4-methylenedioxymethamphetamine (MDMA, ecstasy) produces an acute release of 5-HT in the brain, together with increased locomotion and hyperthermia...