saccades

Summary

Summary: An abrupt voluntary shift in ocular fixation from one point to another, as occurs in reading.

Top Publications

  1. ncbi Neural basis of a perceptual decision in the parietal cortex (area LIP) of the rhesus monkey
    M N Shadlen
    Howard Hughes Medical Institute, Department of Physiology and Biophysics, and Regional Primate Research Center, University of Washington, Seattle, Washington 98195 7290, USA
    J Neurophysiol 86:1916-36. 2001
  2. ncbi Ultra-rapid object detection with saccadic eye movements: visual processing speed revisited
    Holle Kirchner
    Centre de Recherche Cerveau et Cognition UMR 5549, CNRS Université Paul Sabatier Toulouse 3, Faculte de Medecine de Rangueil, 31062 Toulouse Cedex 9, France
    Vision Res 46:1762-76. 2006
  3. ncbi Transient induced gamma-band response in EEG as a manifestation of miniature saccades
    Shlomit Yuval-Greenberg
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem 91905, Israel
    Neuron 58:429-41. 2008
  4. ncbi Fast saccades toward faces: face detection in just 100 ms
    Sébastien M Crouzet
    Centre de Recherche Cerveau and Cognition, UMR, CNRS, Universite Toulouse, Toulouse, France
    J Vis 10:16.1-17. 2010
  5. ncbi Eye movements in reading and information processing: 20 years of research
    K Rayner
    Department of Psychology, University of Massachusetts, Amherst 01003, USA
    Psychol Bull 124:372-422. 1998
  6. ncbi Role of the basal ganglia in the control of purposive saccadic eye movements
    O Hikosaka
    Department of Physiology, Juntendo University, School of Medicine, Tokyo, Japan
    Physiol Rev 80:953-78. 2000
  7. ncbi Lateral habenula as a source of negative reward signals in dopamine neurons
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 4435, USA
    Nature 447:1111-5. 2007
  8. ncbi Basal ganglia orient eyes to reward
    Okihide Hikosaka
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Neurophysiol 95:567-84. 2006
  9. ncbi Saccade target selection and object recognition: evidence for a common attentional mechanism
    H Deubel
    Max Planck Institut für Psychologische Forschung, Munchen, Germany
    Vision Res 36:1827-37. 1996
  10. ncbi Neural control of voluntary movement initiation
    D P Hanes
    Department of Psychology, Wilson Hall, Vanderbilt University, Nashville, TN 37240, USA
    Science 274:427-30. 1996

Research Grants

  1. FUNCTION OF MIDBRAIN STRUCTURES IN EYE MOVEMENT CONTROL
    DAVID WAITZMAN; Fiscal Year: 2005
  2. OCULOMOTOR CONTROL AND GAIT IN PARKINSON DISEASE
    GAMMON EARHART; Fiscal Year: 2009
  3. CONTROL OF EYELIDS IN NORMAL AND PATHOLOGICAL STATES
    LESLIE EVINGER; Fiscal Year: 1993
  4. Coding of Auditory Space in the Avian Brain
    JOSE L PENA; Fiscal Year: 2010
  5. Neural Integration of Eye and Head Movements
    Neeraj Gandhi; Fiscal Year: 2007
  6. CEREBELLAR NUCLEI IN EYE MOVEMENT CONTROL AND ADAPTATION
    Farrel Robinson; Fiscal Year: 2003
  7. CORTICAL PLANNING AND CONTROL OF SMOOTH PURSUIT
    Stephen Heinen; Fiscal Year: 2001
  8. Eye Movement Control in Normal Elderly and MCI
    Adam L Boxer; Fiscal Year: 2010
  9. The Neurophysiology of Spatial Vision
    MICHAEL ELLIS GOLDBERG; Fiscal Year: 2010
  10. CORTICAL CONTRIBUTIONS TO THE CONTROL OF EYE MOVEMENTS
    Mark Segraves; Fiscal Year: 2004

Detail Information

Publications321 found, 100 shown here

  1. ncbi Neural basis of a perceptual decision in the parietal cortex (area LIP) of the rhesus monkey
    M N Shadlen
    Howard Hughes Medical Institute, Department of Physiology and Biophysics, and Regional Primate Research Center, University of Washington, Seattle, Washington 98195 7290, USA
    J Neurophysiol 86:1916-36. 2001
    ..The time course of the neural response suggests that LIP accumulates sensory signals relevant to the selection of a target for an eye movement...
  2. ncbi Ultra-rapid object detection with saccadic eye movements: visual processing speed revisited
    Holle Kirchner
    Centre de Recherche Cerveau et Cognition UMR 5549, CNRS Université Paul Sabatier Toulouse 3, Faculte de Medecine de Rangueil, 31062 Toulouse Cedex 9, France
    Vision Res 46:1762-76. 2006
    ..when two scenes are simultaneously flashed in the left and right hemifields, human participants can reliably make saccades to the side containing an animal in as little as 120 ms...
  3. ncbi Transient induced gamma-band response in EEG as a manifestation of miniature saccades
    Shlomit Yuval-Greenberg
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem 91905, Israel
    Neuron 58:429-41. 2008
    ..quot; The time course of the iGBR is related to an increase in the rate of saccades following a period of poststimulus saccadic inhibition...
  4. ncbi Fast saccades toward faces: face detection in just 100 ms
    Sébastien M Crouzet
    Centre de Recherche Cerveau and Cognition, UMR, CNRS, Universite Toulouse, Toulouse, France
    J Vis 10:16.1-17. 2010
    ..J. Thorpe (2006) found that when two images are simultaneously flashed in the left and right visual fields, saccades toward the side with an animal can be initiated in as little as 120-130 ms...
  5. ncbi Eye movements in reading and information processing: 20 years of research
    K Rayner
    Department of Psychology, University of Massachusetts, Amherst 01003, USA
    Psychol Bull 124:372-422. 1998
    ..are (a) the characteristics of eye movements, (b) the perceptual span, (c) integration of information across saccades, (d) eye movement control, and (e) individual differences (including dyslexia)...
  6. ncbi Role of the basal ganglia in the control of purposive saccadic eye movements
    O Hikosaka
    Department of Physiology, Juntendo University, School of Medicine, Tokyo, Japan
    Physiol Rev 80:953-78. 2000
    In addition to their well-known role in skeletal movements, the basal ganglia control saccadic eye movements (saccades) by means of their connection to the superior colliculus (SC)...
  7. ncbi Lateral habenula as a source of negative reward signals in dopamine neurons
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 4435, USA
    Nature 447:1111-5. 2007
    ..These results suggest that the inhibitory input from the lateral habenula plays an important role in determining the reward-related activity of dopamine neurons...
  8. ncbi Basal ganglia orient eyes to reward
    Okihide Hikosaka
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Neurophysiol 95:567-84. 2006
    ..These data support a specific form of reinforcement learning theories, but also suggest further refinement of the theory...
  9. ncbi Saccade target selection and object recognition: evidence for a common attentional mechanism
    H Deubel
    Max Planck Institut für Psychologische Forschung, Munchen, Germany
    Vision Res 36:1827-37. 1996
    ..The results favor a model in which a single attentional mechanism selects objects for perceptual processing and recognition, and also provides the information necessary for motor action...
  10. ncbi Neural control of voluntary movement initiation
    D P Hanes
    Department of Psychology, Wilson Hall, Vanderbilt University, Nashville, TN 37240, USA
    Science 274:427-30. 1996
    ..This finding elucidates a specific link between motor behavior and activation of neurons in the cerebral cortex...
  11. ncbi Selective gating of visual signals by microstimulation of frontal cortex
    Tirin Moore
    Department of Psychology, Princeton University, Princeton, New Jersey 08544, USA
    Nature 421:370-3. 2003
    ..brief stimulation of retinotopically corresponding sites within the FEF using currents below that needed to evoke saccades. The magnitude of the enhancement depended on the effectiveness of receptive field stimuli as well as on the ..
  12. ncbi A common network of functional areas for attention and eye movements
    M Corbetta
    Department of Neurology, McDonnell Center for Higher Brain Functions, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 21:761-73. 1998
    ..This anatomical overlap is consistent with the hypothesis that attentional and oculomotor processes are tightly integrated at the neural level...
  13. ncbi Look away: the anti-saccade task and the voluntary control of eye movement
    Douglas P Munoz
    Centre for Neuroscience Studies, Department of Physiology, CIHR Group in Sensory Motor Systems, Queen's University, Kingston, Ontario K7L 3N6, Canada
    Nat Rev Neurosci 5:218-28. 2004
  14. ncbi Rostral and dorsal anterior cingulate cortex make dissociable contributions during antisaccade error commission
    Frida E Polli
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 102:15700-5. 2005
    ..These results show that accurate performance involves deactivation of the rACC and other default mode regions and suggest that both rACC and dACC contribute to the evaluation of error responses...
  15. ncbi Top-down versus bottom-up control of attention in the prefrontal and posterior parietal cortices
    Timothy J Buschman
    Picower Institute for Learning and Memory, RIKEN MIT Neuroscience Research Center, and Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Science 315:1860-2. 2007
    ..This result indicates that top-down and bottom-up signals arise from the frontal and sensory cortex, respectively, and different modes of attention may emphasize synchrony at different frequencies...
  16. ncbi The antisaccade: a review of basic research and clinical studies
    S Everling
    MRC Group in Sensory Motor Neuroscience, Department of Physiology, Queen s University, Kingston, Ontario, Canada
    Neuropsychologia 36:885-99. 1998
    ..These findings are discussed and the potential of the antisaccade task for diagnostic purposes is evaluated...
  17. ncbi Spatiotopic transfer of visual-form adaptation across saccadic eye movements
    David Melcher
    Faculty of Psychology, San Raffaele University, Via Olgettina 58, 20132 Milan, Italy
    Curr Biol 15:1745-8. 2005
    ..for visual stability is that internal maps of objects and their visual properties are remapped around the time of saccades, but numerous studies have demonstrated that visual patterns are not combined across saccades...
  18. ncbi Saccadic dysmetria and adaptation after lesions of the cerebellar cortex
    S Barash
    Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel
    J Neurosci 19:10931-9. 1999
    ..For saccades in one horizontal direction, the lesions led to an initial gross hypometria and a permanent abolition of the ..
  19. ncbi Binocular coordination of saccades at far and at near in children and in adults
    Qing Yang
    Laboratoire de Physiologie de la Perception et de l Action, CNRS College de France, Paris, France
    J Vis 3:554-61. 2003
    The goal of the study was to test the quality of binocular coordination of saccades in children and adults, and its dependency upon the viewing distance. Fourteen normal children (4...
  20. ncbi An examination of binocular reading fixations based on sentence corpus data
    Antje Nuthmann
    Department of Psychology, University of Edinburgh, Edinburgh, UK
    J Vis 9:31.1-28. 2009
    ..Fixation disparity accumulates during the course of successive saccades and fixations within a line of text, but only to an extent that does not compromise single binocular vision...
  21. ncbi Neuronal mechanisms of visual stability
    Robert H Wurtz
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bldg 49, Rm 2A50, Bethesda, MD 20892 4435, USA
    Vision Res 48:2070-89. 2008
    ..For the second problem, saccadic suppression, visual masking and corollary discharge are well established mechanisms, and possible neuronal correlates have been identified for each...
  22. ncbi Retinal image shifts, but not eye movements per se, cause alternations in awareness during binocular rivalry
    Loes C J van Dam
    Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
    J Vis 6:1172-9. 2006
    ..Subjects viewed repetitive line patterns, enabling a distinction of saccades that did produce foveal image changes from those that did not. Subjects reported binocular rivalry alternations...
  23. ncbi The role of saccades in exerting voluntary control in perceptual and binocular rivalry
    Loes C J van Dam
    Helmholtz Institute, Utrecht University, Princetonplein 5, 3584 CC Utrecht, The Netherlands
    Vision Res 46:787-99. 2006
    We have investigated the role of saccades and fixation positions in two perceptual rivalry paradigms (slant rivalry and Necker cube) and in two binocular rivalry paradigms (grating and house-face rivalry), and we compared results obtained ..
  24. ncbi Controlled movement processing: superior colliculus activity associated with countermanded saccades
    Martin Paré
    Department of Physiology, Queen s University, Kingston, Ontario, Canada K7L 3N6
    J Neurosci 23:6480-9. 2003
    ..contains neurons with activity patterns sufficient to control both the cancellation and the production of saccades. We used a countermanding task to manipulate the probability that, after the presentation of a stop signal, the ..
  25. ncbi Cerebellar contributions to adaptive control of saccades in humans
    Minnan Xu-Wilson
    Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 29:12930-9. 2009
    The cerebellum may monitor motor commands and through internal feedback correct for anticipated errors. Saccades provide a test of this idea because these movements are completed too quickly for sensory feedback to be useful...
  26. ncbi Neurophysiology and neuroanatomy of reflexive and volitional saccades: evidence from studies of humans
    Jennifer E McDowell
    Departments of Psychology and Neuroscience, Bio Imaging Research Center, Psychology Building, University of Georgia, Athens, GA 30602, USA
    Brain Cogn 68:255-70. 2008
    ..The generation of simple visually guided saccades (redirections of gaze to a visual stimulus or pro-saccades) and more complex volitional saccades require similar ..
  27. ncbi Reward-predicting activity of dopamine and caudate neurons--a possible mechanism of motivational control of saccadic eye movement
    Reiko Kawagoe
    Department of Physiology, Juntendo University, School of Medicine, Tokyo 113-8421, Japan
    J Neurophysiol 91:1013-24. 2004
    ....
  28. ncbi A model of saccade generation based on parallel processing and competitive inhibition
    J M Findlay
    Centre for Vision and Visual Cognition, Department of Psychology, University of Durham, Durham DH1 3LE, England
    Behav Brain Sci 22:661-74; discussion 674-721. 1999
    ..The model accounts for a number of well-established phenomena in target-elicited saccades: the gap effect, express saccades, the remote distractor effect, and the global effect...
  29. ncbi Components of bottom-up gaze allocation in natural images
    Robert J Peters
    Computation and Neural Systems, California Institute of Technology, Mail Code 139 74, Caltech, Pasadena, CA 91125, USA
    Vision Res 45:2397-416. 2005
    ..As models of these interactions become more accurate in predicting behaviorally-relevant salient locations, they become useful to a range of applications in computer vision and human-machine interface design...
  30. ncbi Visual correlates of fixation selection: effects of scale and time
    Benjamin W Tatler
    Sussex Centre for Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, United Kingdom
    Vision Res 45:643-59. 2005
    ..We propose that saccade target selection involves an unchanging intermediate level representation of the scene but that the high-level interpretation of this representation changes over time...
  31. ncbi Adaptive control of saccades via internal feedback
    Haiyin Chen-Harris
    Departments of Biomedical Engineering and Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 28:2804-13. 2008
    Ballistic movements like saccades require the brain to generate motor commands without the benefit of sensory feedback. Despite this, saccades are remarkably accurate...
  32. ncbi Saccade target selection during visual search
    J M Findlay
    Department of Psychology, University of Durham, U K
    Vision Res 37:617-31. 1997
    ..Accurate saccades with short latencies were common but errors sometimes occurred and search for an "oddity" target, ..
  33. ncbi Role of dopamine in the primate caudate nucleus in reward modulation of saccades
    Kae Nakamura
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 4435, USA
    J Neurosci 26:5360-9. 2006
    ..These results suggest that reward-dependent changes in saccadic eye movements depend partly on dopaminergic modulation of neuronal activity in the caudate nucleus...
  34. ncbi Microsaccades counteract visual fading during fixation
    Susana Martinez-Conde
    Barrow Neurological Institute, 350 West Thomas Road, Phoenix, Arizona 85013, USA
    Neuron 49:297-305. 2006
    ..These results reveal a direct link between suppression of microsaccades and fading and suggest a causal relationship between microsaccade production and target visibility during fixation...
  35. ncbi Allocentric spatial referencing of neuronal activity in macaque posterior cingulate cortex
    Heather L Dean
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 26:1117-27. 2006
    Neuronal activity in posterior cingulate cortex (CGp) is modulated by visual stimulation, saccades, and eye position, suggesting a role for this area in visuospatial transformations...
  36. ncbi Attentional cues in real scenes, saccadic targeting, and Bayesian priors
    Miguel P Eckstein
    Department of Psychology, University of California, Santa Barbara, CA 93106, USA
    Psychol Sci 17:973-80. 2006
    ..in real scenes? Controlling for target detectability and retinal eccentricity, we recorded observers' first saccades during search for objects that appeared in expected and unexpected locations within real scenes...
  37. ncbi Congenital nystagmus: hypotheses for its genesis and complex waveforms within a behavioral ocular motor system model
    Jonathan B Jacobs
    Ocular Motor Neurophysiology Laboratory, Louis Stokes Cleveland Veterans Affairs Medical Center, and Department of Neurology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH 44106, USA
    J Vis 4:604-25. 2004
    ..nystagmus (CN) appear to be quite complex, composed of a sustained sinusoidal oscillation punctuated by braking saccades and foveating saccades followed by periods of extended foveation...
  38. ncbi Memory of learning facilitates saccadic adaptation in the monkey
    Yoshiko Kojima
    Department of Physiology, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan
    J Neurosci 24:7531-9. 2004
    A motor learning mechanism called saccadic adaptation ensures accuracy of saccades throughout life despite growth, aging, and some pathologies of the oculomotor plant or nervous system...
  39. ncbi The role of the cerebellum in voluntary eye movements
    F R Robinson
    Department of Biological Structure University of Washington, Seattle, Washington 98195 7420, USA
    Annu Rev Neurosci 24:981-1004. 2001
    ..the posterior vermis and the caudal fastigial nucleus, to which it projects, provide a signal during horizontal saccades to make them fast, accurate, and consistent...
  40. ncbi Neurophysiology and neuroanatomy of reflexive and voluntary saccades in non-human primates
    Kevin Johnston
    Centre for Neuroscience Studies, Queen s University, Kingston, Ont, Canada K7L 3N6
    Brain Cogn 68:271-83. 2008
    ..dorsolateral prefrontal cortex, anterior cingulate (see glossary) cortex and lateral intraparietal area associated with the performance of visually guided saccades, anti-saccades and memory-guided saccades in awake behaving monkeys.
  41. ncbi Trajectories of the human binocular fixation point during conjugate and non-conjugate gaze-shifts
    H Collewijn
    Department of Physiology, Faculty of Medicine, Erasmus University Rotterdam, The Netherlands
    Vision Res 37:1049-69. 1997
    ..of real, continuously visible LED targets that were either iso-vergent at 5-25 deg convergence (conjugate version saccades) or differed in vergence angle (by 5-20 deg) as well as in direction (by 5-60 deg; combined version and vergence)...
  42. ncbi Spatial remapping of the visual world across saccades
    Paul M Bays
    Institute of Cognitive Neuroscience, Institute of Neurology, University College London, Queen Square, London, UK
    Neuroreport 18:1207-13. 2007
    ..Instead, we consider a novel perspective in which the primary function of spatial remapping is to support three key nonperceptual processes: action control, sensorimotor adaptation and spatial memory...
  43. ncbi An adaptive algorithm for fixation, saccade, and glissade detection in eyetracking data
    Marcus Nyström
    Humanities Lab, Lund University, Lund, Sweden
    Behav Res Methods 42:188-204. 2010
    ..Most important, the new algorithm identifies so-called glissades, a wobbling movement at the end of many saccades, as a separate class of eye movements...
  44. ncbi Executive control of gaze by the frontal lobes
    Jeffrey D Schall
    Center for Integrative and Cognitive Neuroscience, Vanderbilt University, Nashville, Tennessee 37240, USA
    Cogn Affect Behav Neurosci 7:396-412. 2007
    ..Neurons in the supplementary eye field do not control directly the initiation of saccades but, instead, signal the production of errors, the anticipation and delivery of reinforcement, and the presence ..
  45. ncbi Vergence deficits in patients with cerebellar lesions
    T Sander
    Department of Neurology, University Hospitals Schleswig Holstein, Campus Lubeck, Lubeck, Germany
    Brain 132:103-15. 2009
    ..Disconjugate fast and slow vergence, conjugate smooth pursuit and saccades were binocularly recorded by a scleral search coil system in 20 patients with acute cerebellar lesions (all ..
  46. ncbi The eye movements of dyslexic children during reading and visual search: impact of the visual attention span
    Chloé Prado
    Laboratoire de Psychologie et Neuro Cognition UMR5105 CNRS, Université Pierre Mendès France, 1251 Avenue Centrale BP 47, 38040 Grenoble Cedex 9, France
    Vision Res 47:2521-30. 2007
    ..The atypical eye movements of some dyslexic readers in reading thus appear to reflect difficulties to increase their VA span according to the task request...
  47. ncbi Supplementary eye field encodes option and action value for saccades with variable reward
    Na Young So
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Neurophysiol 104:2634-53. 2010
    We recorded neuronal activity in the supplementary eye field (SEF) while monkeys made saccades to targets that yielded rewards of variable amount and uncertainty of delivery...
  48. ncbi Temporal discounting of reward and the cost of time in motor control
    Reza Shadmehr
    Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 30:10507-16. 2010
    ..The hyperbolic cost of this delay not only accounts for kinematics of saccades in adults, it also accounts for the faster saccades of children, who temporally discount reward more steeply...
  49. ncbi Binocular coordination of saccades in children with vertigo: dependency on the vergence state
    Maria Pia Bucci
    IRIS Group LPPA, UMR 7152 CNRS College de France, 11, Place M Berthelot, Paris, France
    Vision Res 46:3594-602. 2006
    The present study examines the quality of binocular coordination of saccades at far and near distance in 15 children with symptoms of vertigo headache and equilibrium disorders; these children show normal vestibular function but abnormal ..
  50. ncbi Local morphology predicts functional organization of the dorsal premotor region in the human brain
    Céline Amiez
    Cognitive Neuroscience Unit, Montreal Neurological Institute, McGill University, Montreal, Quebec, H3A 2B4, Canada
    J Neurosci 26:2724-31. 2006
    ....
  51. ncbi Spatial processing in the monkey frontal eye field. II. Memory responses
    M M Umeno
    Laboratory of Sensorimotor Research, National Eye Institute, Bethesda, Maryland 20892, USA
    J Neurophysiol 86:2344-52. 2001
    Monkeys and humans can easily make accurate saccades to stimuli that appear and disappear before an intervening saccade to a different location...
  52. ncbi Cerebellar contributions to the processing of saccadic errors
    P C A van Broekhoven
    Department of Neuroscience, Erasmus MC, Rotterdam 3000 CA, The Netherlands
    Cerebellum 8:403-15. 2009
    b>Saccades are fast eye movements that direct the point of regard to a target in the visual field. Repeated post-saccadic visual errors can induce modifications of the amplitude of these saccades, a process known as saccadic adaptation...
  53. ncbi Trans-saccadic perception
    David Melcher
    Center for Mind Brain Sciences and Department of Cognitive Sciences, University of Trento, Corso Bettini 31, Rovereto 38068, Italy
    Trends Cogn Sci 12:466-73. 2008
    ..We outline five principles of 'trans-saccadic perception' that could help to explain how it is possible - despite discrete sensory input and limited memory - that conscious perception across saccades seems smooth and predictable.
  54. ncbi How the brain obeys Hering's law: a TMS study of the posterior parietal cortex
    Marine Vernet
    IRIS Group, CNRS College de France, 11 place Marcelin Berthelot, Paris, France
    Invest Ophthalmol Vis Sci 49:230-7. 2008
    Human ocular saccades are not perfectly yoked; the origin of this disconjugacy (muscular versus central) remains controversial. The purpose of this study was to test a cortical influence on the binocular coordination of saccades.
  55. ncbi Reduced saccadic resilience and impaired saccadic adaptation due to cerebellar disease
    Heidrun Golla
    Department of Cognitive Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Eur J Neurosci 27:132-44. 2008
    ..mechanism needed to avoid 'fatigue', a gradual drop in saccade amplitude during a long series of stereotypic saccades. To this end we compared the kinematics of saccades of 14 patients suffering from different forms of cerebellar ..
  56. ncbi A pathway in primate brain for internal monitoring of movements
    Marc A Sommer
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Science 296:1480-2. 2002
    ..These results identify a pathway in the brain of the primate Macaca mulatta that conveys corollary discharge signals...
  57. ncbi Parallel and serial neural mechanisms for visual search in macaque area V4
    Narcisse P Bichot
    Laboratory of Neuropsychology, National Institute of Mental Health NIMH, National Institutes of Health, Bethesda, MD 20892, USA
    Science 308:529-34. 2005
    ..Neurons also gave enhanced responses to candidate targets that were selected for saccades, or foveation, reflecting a serial component of visual search...
  58. ncbi Dynamic coding of behaviourally relevant stimuli in parietal cortex
    Louis J Toth
    Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA
    Nature 415:165-8. 2002
    ..However, when cue location was relevant, colour selectivity was virtually absent in LIP. These results demonstrate that selectivity of cortical neurons can change as a function of the required behaviour...
  59. ncbi Contribution of the monkey frontal eye field to covert visual attention
    Claire Wardak
    Institut des Sciences Cognitives, , , 69675 Bron, France
    J Neurosci 26:4228-35. 2006
    ..using multiple microinjections of muscimol, a GABAA agonist, in two macaque monkeys performing visually guided saccades to a single target...
  60. ncbi The roles of vision and eye movements in the control of activities of daily living
    M Land
    Sussex Centre for Neuroscience, School of Biological Sciences, University of Sussex, Brighton, UK
    Perception 28:1311-28. 1999
    ..This type of unconscious attention must be a common phenomenon in everyday life...
  61. ncbi The role of stimulus-driven and goal-driven control in saccadic visual selection
    Wieske van Zoest
    Department of Cognitive Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
    J Exp Psychol Hum Percept Perform 30:746-59. 2004
    ..Instead, they indicate that visual selection is the outcome of 2 independent processes, one stimulus driven and the other goal driven, operating in different time windows...
  62. ncbi The antisaccade task as a research tool in psychopathology: a critical review
    Samuel B Hutton
    Department of Psychology, Sussex University, Brighton, UK
    Psychophysiology 43:302-13. 2006
    ....
  63. ncbi Performance monitoring by the anterior cingulate cortex during saccade countermanding
    Shigehiko Ito
    Center for Integrative and Cognitive Neuroscience, Vanderbilt Vision Research Center, Department of Psychology, Wilson Hall, Vanderbilt University, Nashville, TN 37203, USA
    Science 302:120-2. 2003
    ..No neurons signaled the form of conflict engendered by interruption of saccade preparation produced in this task. These results are consistent with the hypothesis that the anterior cingulate cortex monitors the consequences of actions...
  64. ncbi On the role of frontal eye field in guiding attention and saccades
    Jeffrey D Schall
    Center for Integrative and Cognitive Neuroscience, Vanderbilt Vision Research Center, Department of Psychology, Vanderbilt University, 111 21st Avenue South, 301 Wilson Hall, Nashville, TN 37240, USA
    Vision Res 44:1453-67. 2004
    ..These patterns of activity are consistent with the hypotheses that covert shifts of attention can occur without saccade production and that FEF contributes to covert as well as overt orienting...
  65. ncbi TMS over the left posterior parietal cortex prolongs latency of contralateral saccades and convergence
    Qing Yang
    Laboratoire de Physiologie de la Perception et de l Action, CNRS College de France, Paris
    Invest Ophthalmol Vis Sci 45:2231-9. 2004
    This study explored the role of the left posterior parietal cortex (PPC) in saccades, vergence, and combined saccade-vergence movements by means of transcranial magnetic stimulation (TMS) in humans.
  66. ncbi Timing of target discrimination in human frontal eye fields
    Jacinta O'Shea
    Department of Experimental Psychology, University of Oxford, UK
    J Cogn Neurosci 16:1060-7. 2004
    ..eye field (FEF) neurons discharge in response to behaviorally relevant stimuli that are potential targets for saccades. Distinct visual and motor processes have been dissociated in the FEF of macaque monkeys, but little is known ..
  67. ncbi Spectro-temporal factors in two-dimensional human sound localization
    P M Hofman
    University of Nijmegen, Department of Medical Physics and Biophysics, The Netherlands
    J Acoust Soc Am 103:2634-48. 1998
    ..These findings are incorporated in a conceptual model that accounts for the data and proposes a scheme for the temporal processing of spectral sensory information into a dynamic estimate of sound elevation...
  68. ncbi Age-related performance of human subjects on saccadic eye movement tasks
    D P Munoz
    Department of Physiology, Queen s University, Kingston, Ontario, Canada
    Exp Brain Res 121:391-400. 1998
    ..Elderly subjects (60-79 years of age) had slower SRTs and longer duration saccades than other subject groups...
  69. ncbi Mixed pro and antisaccade performance in children and adults
    Elizabeth L Irving
    University of Waterloo, School of Optometry, Waterloo, Canada
    Brain Res 1255:67-74. 2009
    ..It was concluded that the increased error rates of these two groups are reflective of different processing dynamics...
  70. ncbi Altered control of visual fixation and saccadic eye movements in attention-deficit hyperactivity disorder
    Douglas P Munoz
    Centre for Neuroscience Studies, Canadian Institute of Health Research Group in Sensory Motor Systems, Department of Physiology, Queen s University, Kingston, Ontario, K7L 3N6 Canada
    J Neurophysiol 90:503-14. 2003
    ..In the pro-saccade task, ADHD participants had longer reaction times, greater intra-subject variance, and their saccades had reduced peak velocities and increased durations...
  71. ncbi Lateralized frontal eye field activity precedes occipital activity shortly before saccades: evidence for cortico-cortical feedback as a mechanism underlying covert attention shifts
    Tjerk P Gutteling
    University Medical Center Utrecht, The Netherlands
    J Cogn Neurosci 22:1931-43. 2010
    ..This is consistent with the idea that the FEF exerts a direct modulatory influence on the visual cortex and enhances perception at the saccade end-goal...
  72. ncbi Development of pro- and antisaccades in children with attention-deficit hyperactivity disorder (ADHD) and healthy controls
    C H Klein
    Department of Psychology, Research Group Psychophysiology, University of Freiburg, Freiburg, Germany
    Psychophysiology 40:17-28. 2003
    ..c) augmented proportions of early responses (all conditions), and (d) reduced proportions of express saccades under the prosaccadic gap condition...
  73. ncbi Macaque V1 activity during natural vision: effects of natural scenes and saccades
    Sean P MacEvoy
    Department of Neuroscience, Brown University, Providence, RI 02912, USA
    J Neurophysiol 99:460-72. 2008
    In the present study, we examined the way that scene complexity and saccades combine to sculpt the temporal response patterns of V1 neurons...
  74. ncbi Switching between gap and overlap pro-saccades: cost or benefit?
    Marine Vernet
    IRIS Laboratory, CNRS, FRE 3154, Service d Ophtalmologie, Assistance Publique, Hopitaux de Paris, Hôpital Européen Georges Pompidou Univ Paris V, 20, rue Leblanc, 75015 Paris, France
    Exp Brain Res 197:49-58. 2009
    Triggering of saccades depends on the task: in the gap task, fixation point switches off and target appears after a gap period; in the overlap task, target appears while fixation point is still on...
  75. ncbi Anti-saccades away from faces: evidence for an influence of high-level visual processes on saccade programming
    Iain D Gilchrist
    Department of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol, BS8 1TN, UK
    Exp Brain Res 173:708-12. 2006
    The anti-saccade task is an important tool for investigating both the generation of voluntary saccades and the suppression of involuntary, stimulus driven, saccades...
  76. ncbi The parallel programming of voluntary and reflexive saccades
    Robin Walker
    Department of Psychology, Royal Holloway, University of London, Egham, Surrey TW20 0EX, UK
    Vision Res 46:2082-93. 2006
    ..investigate the parallel programming of consecutive, stimulus-elicited ('reflexive') and endogenous ('voluntary') saccades. The mean latency of voluntary saccades, made following the first reflexive saccades in two-step conditions, was ..
  77. ncbi Role of the posterior parietal cortex in the initiation of saccades and vergence: right/left functional asymmetry
    Zoi Kapoula
    Laboratoire de Physiologie de la Perception et de l Action, UMR 7124 CNRS College de France, 11, place Marcelin Berthelot 75005 Paris, France
    Ann N Y Acad Sci 1039:184-97. 2005
    This study explored in humans the role of the posterior parietal cortex (PPC) in saccades, vergence, and combined saccade-vergence movements by means of transcranial magnetic stimulation (TMS)...
  78. ncbi Spatial and effector processing in the human parietofrontal network for reaches and saccades
    S M Beurze
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, NL 6500 HE, Nijmegen, The Netherlands
    J Neurophysiol 101:3053-62. 2009
    ..Taken together, our results suggest that the relative weight of spatial goal and effector selectivity changes along the parietofrontal network, depending on the status of the movement plan...
  79. ncbi Effects of salience are short-lived
    Mieke Donk
    Department of Cognitive Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 1, 1081BT Amsterdam, The Netherlands
    Psychol Sci 19:733-9. 2008
    ..These results suggest that salience is represented in the visual system only briefly after a visual image enters the brain...
  80. ncbi Stable individual differences across images in human saccadic eye movements
    Monica S Castelhano
    Department of Psychology, University of Massachusetts Amherst, Amherst, MA, USA
    Can J Exp Psychol 62:1-14. 2008
    ..Eye movement characteristics differ across individuals, but there is a great deal of consistency within individuals when viewing different types of images...
  81. ncbi Individual differences in the asymmetry of binocular saccades, analysed with mixed-effects models
    Wilhelm Bernhard Kloke
    , Ardeystr. 67, D-44139 Dortmund, Germany
    Biol Psychol 73:220-6. 2006
    We analysed the reliability of individual differences in parameters of binocular saccadic eye movements. During saccades between isovergent targets, the movement of the right and left eye are not exactly symmetrical (conjugate)...
  82. ncbi Perceptual decision making in less than 30 milliseconds
    Terrence R Stanford
    Department of Neurobiology and Anatomy, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Nat Neurosci 13:379-85. 2010
    ....
  83. ncbi Cerebellar lesions impair rapid saccade amplitude adaptation
    A Straube
    Department of Neurology, Klinikum Grosshadern, Munich, Germany
    Neurology 57:2105-8. 2001
    ....
  84. ncbi Visual error is the stimulus for saccade gain adaptation
    C T Noto
    Department of Biological Structure and Regional Primate Research Center, University of Washington, Seattle, WA 98195 7420, USA
    Brain Res Cogn Brain Res 12:301-5. 2001
    Saccade accuracy is fundamental to clear vision. The brain maintains saccade accuracy by altering commands for saccades that are consistently inaccurate...
  85. ncbi Disruption of saccadic adaptation with repetitive transcranial magnetic stimulation of the posterior cerebellum in humans
    Ned Jenkinson
    Nuffield Department of Surgery, University of Oxford, Oxford, UK
    Cerebellum 9:548-55. 2010
    ..It is possible to rapidly adapt saccades in the laboratory by introducing a discrepancy between the intended and actual saccadic target...
  86. ncbi Developmental functions for saccadic eye movement parameters derived from pro- and antisaccade tasks
    C Klein
    Department of Psychology, University of Freiburg, Germany
    Exp Brain Res 139:1-17. 2001
    ..34) reaction times (RT) and their standard deviations (0.26-0.45), and negligible for the proportion of express saccades. (3) The age variables (particularly Age(-1)), furthermore, predicted some of the effects of the experimental ..
  87. ncbi When are attention and saccade preparation dissociated?
    Artem V Belopolsky
    Department of Cognitive Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
    Psychol Sci 20:1340-7. 2009
    To understand the mechanisms of visual attention, it is crucial to know the relationship between attention and saccades. Some theories propose a close relationship, whereas others view the attention and saccade systems as completely ..
  88. ncbi Preparatory activations across a distributed cortical network determine production of express saccades in humans
    Jordan P Hamm
    Department of Psychology, University of Georgia, Athens, Georgia 30602, USA
    J Neurosci 30:7350-7. 2010
    ..These processes were examined with dense-array EEG as humans completed saccades in a "gap" paradigm known to elicit bimodal variability in response times, including separate ..
  89. ncbi Auditory saccade impairment after central thalamus lesions
    M Versino
    Dipartimento Scienze Neurologiche, Universita di Pavia, Italy
    J Neurol Neurosurg Psychiatry 68:234-7. 2000
    Visual and auditory saccades were studied in three patients with an isolated lesion located in the central thalamus...
  90. ncbi Binocular motor coordination during saccades and fixations while reading: a magnitude and time analysis
    Marine Vernet
    IRIS Laboratory, CNRS, FRE 3154 Assistance Publique des Hôpitaux de Paris, Paris, France
    J Vis 9:2. 2009
    Reading involves saccades and fixations. Misalignment of the eyes should be small enough to allow sensory fusion. Recent studies reported disparity of the eyes during fixations. This study examines disconjugacy, i.e...
  91. ncbi Functional MRI mapping of brain activation during visually guided saccades and antisaccades: cortical and subcortical networks
    Tetsuya Matsuda
    Department of Neuropsychiatry, Nihon University School of Medicine, 30 1 Oyaguchi Kamimachi, Itabashi ku, Tokyo 173 8610, Japan
    Psychiatry Res 131:147-55. 2004
    ..functional magnetic resonance imaging (fMRI), we investigated the neural networks required to inhibit reflexive saccades and to voluntarily generate saccades...
  92. ncbi Idiosyncratic characteristics of saccadic eye movements when viewing different visual environments
    T J Andrews
    Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA
    Vision Res 39:2947-53. 1999
    ..The independent covariance of eye movements during different visual tasks shows that saccadic eye movements during active tasks like reading or visual search differ from those engaged during the passive inspection of visual scenes...
  93. ncbi Development of prosaccade and antisaccade task performance in participants aged 6 to 26 years
    C Klein
    Research Group Psychophysiology, University of Freiburg, Germany
    Psychophysiology 38:179-89. 2001
    ..In three age groups (6-7, 10-11, 18-26 years), saccades during pro- and antisaccade tasks with 200-ms gap and overlap and during a fixation task were measured...
  94. ncbi Judgments of path, not heading, guide locomotion
    Richard M Wilkie
    Institute of Psychological Sciences, University of Leeds, Leeds, United Kingdom
    J Exp Psychol Hum Percept Perform 32:88-96. 2006
    ..In light of these results, the authors suggest it is unlikely that heading is primarily used by the visual system to support active steering...
  95. ncbi Prosaccades and antisaccades to onsets and color singletons: evidence that erroneous prosaccades are not reflexive
    Richard Godijn
    Beckman Institute, University of Illinois, 405 North Mathews Avenue, Urbana, IL 61801, USA
    Exp Brain Res 172:439-48. 2006
    ..The results showed that participants often made erroneous saccades toward the onset or color singleton when they were the search target in the antisaccade condition, but not when ..
  96. ncbi Movement intention is better predicted than attention in the posterior parietal cortex
    Rodrigo Quian Quiroga
    Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
    J Neurosci 26:3615-20. 2006
    ..Moreover, neural signals in the parietal reach region (PRR) gave better predictions of reaches than saccades, whereas signals in the lateral intraparietal area (LIP) gave better predictions of saccades than reaches...
  97. ncbi Foveal visual strategy during self-motion is independent of spatial attention
    Min Wei
    Department of Neurobiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA
    J Neurosci 26:564-72. 2006
    ....
  98. ncbi Target selection for visually guided reaching in macaque
    Joo Hyun Song
    Smith Kettlewell Eye Research Institute, 2318 Fillmore St, San Francisco, CA 94115, USA
    J Neurophysiol 99:14-24. 2008
    ..Previous studies of saccades and attention have shown that target selection in this task is easier when a greater number of homogenous ..
  99. ncbi Task-dependent effects of social attention on saccadic reaction times
    Michael J Koval
    Graduate Program in Neuroscience, University of Western Ontario, London, ON, N6G 2V4, Canada
    Exp Brain Res 167:475-80. 2005
    ..These findings suggest that the effect of social gaze cues on SRTs is task dependent...
  100. ncbi Working memory can guide pop-out search
    David Soto
    Behavioural Brain Sciences, School of Psychology, University of Birmingham, Birmingham B15 2TT, UK
    Vision Res 46:1010-8. 2006
    ..Despite this, the prime in WM affected responses latencies and the direction of the first saccade. Top-down search, guided by the contents of WM, can modulate selection even when salient bottom-up cues are present...
  101. ncbi Relation of frontal eye field activity to saccade initiation during a countermanding task
    Joshua W Brown
    Vanderbilt Vision Research Center, Department of Psychology, Vanderbilt University, Nashville, TN 37203, USA
    Exp Brain Res 190:135-51. 2008
    ..Previous research found that saccades are initiated when the activity of movement-related neurons reaches a threshold, and saccades are withheld if the ..

Research Grants88

  1. FUNCTION OF MIDBRAIN STRUCTURES IN EYE MOVEMENT CONTROL
    DAVID WAITZMAN; Fiscal Year: 2005
    ..the velocity to position integrator which is essential in oculomotor feedback control should generate hypermetric saccades. 3)Determine if the map of saccade amplitude in the intermediate and deep layers of the SC is modified following ..
  2. OCULOMOTOR CONTROL AND GAIT IN PARKINSON DISEASE
    GAMMON EARHART; Fiscal Year: 2009
    ..H2a: Participants with PD will demonstrate slower, smaller saccades at turn initiation and will make many small saccades while controls will make a few large saccades during turns...
  3. CONTROL OF EYELIDS IN NORMAL AND PATHOLOGICAL STATES
    LESLIE EVINGER; Fiscal Year: 1993
    ..Patients with abnormally slow saccadic eye movements can make normal velocity saccades when they combine the saccade with a voluntary blink...
  4. Coding of Auditory Space in the Avian Brain
    JOSE L PENA; Fiscal Year: 2010
    ..are processed in parallel in order to control two output variables (horizontal and vertical coordinates of head saccades)...
  5. Neural Integration of Eye and Head Movements
    Neeraj Gandhi; Fiscal Year: 2007
    ..neural discharge and extraocular motor neurons is demonstrated by recording activity during head-restrained saccades. In contrast, a relationship between spikes and neck motor neurons is only inferred by observing activity during ..
  6. CEREBELLAR NUCLEI IN EYE MOVEMENT CONTROL AND ADAPTATION
    Farrel Robinson; Fiscal Year: 2003
    b>Saccades, smooth pursuit, and vergence need to be extremely accurate to provide clear vision...
  7. CORTICAL PLANNING AND CONTROL OF SMOOTH PURSUIT
    Stephen Heinen; Fiscal Year: 2001
    To maintain clear vision of an object at the fovea, the eyes must be moved to that object. Rapid eye movements, or saccades are used to acquire stationary objects, while smooth pursuit is used to stabilize moving objects...
  8. Eye Movement Control in Normal Elderly and MCI
    Adam L Boxer; Fiscal Year: 2010
    ..Age-related changes occur in the brain network that controls saccades and covert shifts of attention, and the structure and function of this network are also highly sensitive to the ..
  9. The Neurophysiology of Spatial Vision
    MICHAEL ELLIS GOLDBERG; Fiscal Year: 2010
    ..before an intervening eye movement, but they also slightly mislocalize saccade targets flashed immediately around saccades. Aim 3 is to study the spatial and temporal courses of the remapping process and the effects of inactivation of ..
  10. CORTICAL CONTRIBUTIONS TO THE CONTROL OF EYE MOVEMENTS
    Mark Segraves; Fiscal Year: 2004
    ..The FEF contains neurons whose firing is related to the generation of saccades, and projects to the superior colliculus as well as to other oculomotor regions of the brainstem...
  11. DYNAMIC MACAQUE BASAL GANGLIA SACCADE NETWORKS
    ANN GRAYBIEL; Fiscal Year: 2004
    ..Evidence suggests that this circuit is a release circuit for saccades. The oculomotor zone has been investigated intensively with conventional single unit recording methods in highly ..
  12. NEUROPHYSIOLOGY OF THE OCULOMOTOR SYSTEM
    Albert Fuchs; Fiscal Year: 2003
    ..The objective of this application is to investigate how the brain ensures that rapid eye movements, called saccades, land accurately on objects of interest...
  13. COORDINATION OF VOLUNTARY EYE MOVEMENTS
    Richard Krauzlis; Fiscal Year: 2002
    ..data indicating that there is functional overlap between the neural mechanisms for pursuit and saccades. The objective of this application is to investigate the nature and degree of this functional overlap In ..
  14. FUNCTIONAL ORGANIZATION OF THE FRONTAL EYE FIELD
    Charles Bruce; Fiscal Year: 2003
    ..studies of neurons in the saccadic region of FEF (FEFsac) find different combinations of activity related to saccades, visual inputs, and eye position as well as to behavioral states including memory and anticipation; similar ..
  15. INVESTIGATION AND TREATMENT OF OCULAR MOTOR DISORDERS
    RICHARD JOHN LEIGH; Fiscal Year: 2010
    ..during the prior funding period: The first project concerns the beginning and ending of rapid eye movements (saccades)...
  16. COORDINATION OF VOLUNTARY EYE MOVEMENTS
    Richard Krauzlis; Fiscal Year: 2005
    ..Although pursuit and saccades have long been viewed as distinct motor systems, there is growing evidence that certain crucial steps are shared...
  17. Dynamic Basal Ganglia Saccade Networks
    ANN GRAYBIEL; Fiscal Year: 2007
    ..the substantia nigra pars reticulata which in turn projects to, and inhibits the superior colliculus and inhibits saccades thereby. This basal ganglia pathway is used as a prime example of the release functions of the basal ganglia...
  18. Dynamic Basal Ganglia Saccade Networks
    Ann M Graybiel; Fiscal Year: 2010
    ..the substantia nigra pars reticulata which in turn projects to, and inhibits the superior colliculus and inhibits saccades thereby. This basal ganglia pathway is used as a prime example of the release functions of the basal ganglia...
  19. Eye Movements and Visual Perception
    Bart Krekelberg; Fiscal Year: 2009
    ..is therefore invoked to blunt visual perception and hide imperfections in the coordinate transform during saccades. Our hypothesis is that both mechanisms are implemented in early visual cortical areas...