ophthalmological diagnostic techniques

Summary

Summary: Methods and procedures for the diagnosis of diseases of the eye or of vision disorders.

Top Publications

  1. ncbi Assessment of the biomechanical properties of the cornea with the ocular response analyzer in normal and keratoconic eyes
    Sunil Shah
    Birmingham Heartlands and Solihull NHS Trust, Solihull, United Kingdom
    Invest Ophthalmol Vis Sci 48:3026-31. 2007
  2. ncbi Comparison of optical coherence tomography and ultrasound biomicroscopy for detection of narrow anterior chamber angles
    Sunita Radhakrishnan
    Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Arch Ophthalmol 123:1053-9. 2005
  3. ncbi Technique for detecting serial topographic changes in the optic disc and peripapillary retina using scanning laser tomography
    B C Chauhan
    Department of Ophthalmology, Dalhousie University, Halifax, Nova Scotia, Canada
    Invest Ophthalmol Vis Sci 41:775-82. 2000
  4. pmc Intraobserver and interobserver reproducibility in the evaluation of ultrasonic pachymetry measurements of central corneal thickness
    S Miglior
    Department of Ophthalmology, University of Milan Bicocca, Department of Neurosciences and Biomedical Technologies, Via Cadore 48, 20052 Monza, Milan, Italy
    Br J Ophthalmol 88:174-7. 2004
  5. pmc Enhanced corneal compensation for scanning laser polarimetry on eyes with atypical polarisation pattern
    M Toth
    Department of Ophthalmology, Semmelweis University, Budapest, Hungary
    Br J Ophthalmol 89:1139-42. 2005
  6. ncbi Comparative estimation of anterior chamber depth by ultrasonography, Orbscan II, and IOLMaster
    Aravind R Reddy
    Leeds Teaching Hospitals, University of Teesside, Middlesbrough, England, United Kingdom
    J Cataract Refract Surg 30:1268-71. 2004
  7. ncbi Principles of ray tracing aberrometry
    V V Molebny
    Institute of Biomedical Engineering, Kiev, Ukraine
    J Refract Surg 16:S572-5. 2000
  8. ncbi Central corneal thickness measurement with the Pentacam Scheimpflug system, optical low-coherence reflectometry pachymeter, and ultrasound pachymetry
    Yaniv Barkana
    Department of Ophthalmology, Assaf Harofe Medical Center, Beer Yaacov, Zerifin, Israel
    J Cataract Refract Surg 31:1729-35. 2005
  9. ncbi Determining in vivo biomechanical properties of the cornea with an ocular response analyzer
    David A Luce
    Reichert Inc, Depew, New York, USA
    J Cataract Refract Surg 31:156-62. 2005
  10. ncbi Relationship between visual field sensitivity and retinal nerve fiber layer thickness as measured by scanning laser polarimetry
    Patricio G Schlottmann
    Glaucoma Research Unit, Moorfields Eye Hospital, London, United Kingdom
    Invest Ophthalmol Vis Sci 45:1823-9. 2004

Research Grants

  1. Noninvsive Imaging of Chorio-retinal Oxygen Tension
    Mahnaz Shahidi; Fiscal Year: 2005
  2. Telemedical Diagnosis of Retinopathy of Prematurity
    Michael Chiang; Fiscal Year: 2007
  3. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Donald Budenz; Fiscal Year: 2008
  4. Retinal Image Quality in Retinal-diseased Eyes
    Mahnaz Shahidi; Fiscal Year: 2010
  5. OPTICAL AND RETINAL LIMITS TO HUMAN VISUAL PERFORMANCE
    Larry N Thibos; Fiscal Year: 2010
  6. OUTCOME MEASURES FOR CLINICAL TRIALS IN STRABISMUS
    Jonathan Holmes; Fiscal Year: 2008
  7. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Robert Weinreb; Fiscal Year: 2008
  8. PATHOGENESIS OF RETINOPATHY OF PREMATURITY
    Jonathan Holmes; Fiscal Year: 2003
  9. EARLY DETECTION OF GLAUCOMA DAMAGE
    Henry Jampel; Fiscal Year: 2004
  10. Gene Therapy of Autosomal Recessive RP
    Simon Petersen Jones; Fiscal Year: 2006

Detail Information

Publications218 found, 100 shown here

  1. ncbi Assessment of the biomechanical properties of the cornea with the ocular response analyzer in normal and keratoconic eyes
    Sunil Shah
    Birmingham Heartlands and Solihull NHS Trust, Solihull, United Kingdom
    Invest Ophthalmol Vis Sci 48:3026-31. 2007
    ..To compare hysteresis, a novel measure of ocular rigidity (viscoelasticity) in normal and keratoconic eyes...
  2. ncbi Comparison of optical coherence tomography and ultrasound biomicroscopy for detection of narrow anterior chamber angles
    Sunita Radhakrishnan
    Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Arch Ophthalmol 123:1053-9. 2005
    ..To assess the accuracy of classification of narrow anterior chamber (AC) angles using quantitative imaging by optical coherence tomography (OCT) and ultrasound biomicroscopy (UBM)...
  3. ncbi Technique for detecting serial topographic changes in the optic disc and peripapillary retina using scanning laser tomography
    B C Chauhan
    Department of Ophthalmology, Dalhousie University, Halifax, Nova Scotia, Canada
    Invest Ophthalmol Vis Sci 41:775-82. 2000
    ..To describe and evaluate a new statistical technique for detecting topographic changes in the optic disc and peripapillary retina measured with confocal scanning laser tomography...
  4. pmc Intraobserver and interobserver reproducibility in the evaluation of ultrasonic pachymetry measurements of central corneal thickness
    S Miglior
    Department of Ophthalmology, University of Milan Bicocca, Department of Neurosciences and Biomedical Technologies, Via Cadore 48, 20052 Monza, Milan, Italy
    Br J Ophthalmol 88:174-7. 2004
    ..To assess reproducibility of central corneal thickness (CCT) measurement by means of ultrasonic pachymetry...
  5. pmc Enhanced corneal compensation for scanning laser polarimetry on eyes with atypical polarisation pattern
    M Toth
    Department of Ophthalmology, Semmelweis University, Budapest, Hungary
    Br J Ophthalmol 89:1139-42. 2005
    ....
  6. ncbi Comparative estimation of anterior chamber depth by ultrasonography, Orbscan II, and IOLMaster
    Aravind R Reddy
    Leeds Teaching Hospitals, University of Teesside, Middlesbrough, England, United Kingdom
    J Cataract Refract Surg 30:1268-71. 2004
    ..To assess the degree of agreement of anterior chamber depth (ACD) measurements by 2 optical devices (Orbscan II and IOLMaster) and compare them with contact ultrasound A-scan...
  7. ncbi Principles of ray tracing aberrometry
    V V Molebny
    Institute of Biomedical Engineering, Kiev, Ukraine
    J Refract Surg 16:S572-5. 2000
    ..Ray tracing aberrometry developed by the Institute of Biomedical Engineering (Kiev) and first tested at the Vardinoyannion Eye Institute of Crete is a promising technique for eye refraction aberration and refraction mapping...
  8. ncbi Central corneal thickness measurement with the Pentacam Scheimpflug system, optical low-coherence reflectometry pachymeter, and ultrasound pachymetry
    Yaniv Barkana
    Department of Ophthalmology, Assaf Harofe Medical Center, Beer Yaacov, Zerifin, Israel
    J Cataract Refract Surg 31:1729-35. 2005
    ....
  9. ncbi Determining in vivo biomechanical properties of the cornea with an ocular response analyzer
    David A Luce
    Reichert Inc, Depew, New York, USA
    J Cataract Refract Surg 31:156-62. 2005
    ..To study the results of an ocular response analyzer (ORA) to determine the biomechanical properties of the cornea and their relationship to intraocular pressure (IOP)...
  10. ncbi Relationship between visual field sensitivity and retinal nerve fiber layer thickness as measured by scanning laser polarimetry
    Patricio G Schlottmann
    Glaucoma Research Unit, Moorfields Eye Hospital, London, United Kingdom
    Invest Ophthalmol Vis Sci 45:1823-9. 2004
    ..To evaluate the strength and pattern of the relationship between visual field (VF) sensitivity and retinal nerve fiber layer (RNFL) thickness measurements by scanning laser polarimetry (SLP)...
  11. ncbi Discriminating between normal and glaucomatous eyes using the Heidelberg Retina Tomograph, GDx Nerve Fiber Analyzer, and Optical Coherence Tomograph
    L M Zangwill
    Glaucoma Center, Department of Ophthalmology, University of California-San Diego, La Jolla, CA 92093-0946, USA
    Arch Ophthalmol 119:985-93. 2001
    ....
  12. ncbi Comparison of the GDx VCC scanning laser polarimeter, HRT II confocal scanning laser ophthalmoscope, and stratus OCT optical coherence tomograph for the detection of glaucoma
    Felipe A Medeiros
    Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, CA 92093 0946, USA
    Arch Ophthalmol 122:827-37. 2004
    ....
  13. ncbi Relationship between refractive error and monochromatic aberrations of the eye
    Xu Cheng
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    Optom Vis Sci 80:43-9. 2003
    ..To examine the relationship between ametropia and optical aberrations in a population of 200 normal human eyes with refractive errors spanning the range from +5.00 to -10.00 D...
  14. doi Ocular Response Analyzer in subjects with and without glaucoma
    Michael Sullivan-Mee
    Albuquerque VA Medical Center, Albuquerque, New Mexico 87108, USA
    Optom Vis Sci 85:463-70. 2008
    ..This study was devised to investigate whether ORA-derived IOP and corneal biomechanical variables might be useful in discriminating between subjects with and without primary open-angle glaucoma (GLC)...
  15. ncbi Comparison of higher-order wavefront aberrations with 3 aberrometers
    Chung Ling Liang
    Department of Ophthalmology, Kaohsiung Municipal United Hospital, Kaohsiung, Taiwan
    J Cataract Refract Surg 31:2153-6. 2005
    ..To evaluate the agreement of higher-order aberrations (HOAs) between aberrometers based on the Hartmann-Shack wavefront technology...
  16. ncbi Wavefront analysis in normal refractive surgery candidates
    Marcelo V Netto
    The Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    J Refract Surg 21:332-8. 2005
    ..To quantify the higher order aberrations of refractive surgery candidates and compare the wavefront-determined refractions with manifest refractions refined with a +/- 0.25 Jackson cross cylinder...
  17. ncbi Progression of visual field loss in open angle glaucoma in the Melbourne Visual Impairment Project
    Mimiwati Zahari
    Centre for Eye Research Australia, The University of Melbourne, Melbourne, Victoria, Australia
    Clin Experiment Ophthalmol 34:20-6. 2006
    ..To quantify the progression of visual field loss in participants with open angle glaucoma...
  18. ncbi Principles of Tscherning aberrometry
    M Mrochen
    Department of Ophthalmology at the University of Zurich, Switzerland
    J Refract Surg 16:S570-1. 2000
    ..The deviations of all spots from their ideal regular positions are measured by means of a personal computer, and from these values the optical aberrations are computed in the form of Zernike polynomials up to the 8th order...
  19. ncbi Comparison of 4 methods for quantifying posterior capsule opacification
    Oliver Findl
    Department of Ophthalmology, University of Vienna, Vienna, Austria
    J Cataract Refract Surg 29:106-11. 2003
    ..A test set of digital retroillumination images of 100 eyes with PCO of varying degrees was used...
  20. ncbi Repeatability and reproducibility of corneal thickness measurements by optical coherence tomography
    Sarah Muscat
    Tennent Institute of Ophthalmology, University of Glasgow, Glasgow, Scotland, United Kingdom
    Invest Ophthalmol Vis Sci 43:1791-5. 2002
    ..To assess the repeatability and interoperator and intersession reproducibility of central corneal thickness (CCT) measurements made by a commercially available optical coherence tomography (OCT) system...
  21. ncbi Comparative study of central corneal thickness measurement with slit-lamp optical coherence tomography and visante optical coherence tomography
    Haitao Li
    Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China
    Ophthalmology 115:796-801.e2. 2008
    ..To evaluate the repeatability and reproducibility of central corneal thickness (CCT) measurements obtained by 2 anterior segment optical coherence tomography (OCT) imaging systems and to examine their agreements with ultrasound pachymetry...
  22. ncbi Diagnostic capability of scanning laser polarimetry with variable cornea compensator in Indian patients with early primary open-angle glaucoma
    Rajul S Parikh
    LV Prasad Eye Institute, Hyderabad, India
    Ophthalmology 115:1167-1172.e1. 2008
    ..To evaluate the diagnostic ability of scanning laser polarimetry (GDx variable corneal compensator [VCC]) for early glaucoma in Asian Indian eyes...
  23. ncbi Comparison of three methods of measuring corneal thickness and anterior chamber depth
    Wolf Buehl
    Department of Ophthalmology, Medical University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    Am J Ophthalmol 141:7-12. 2006
    ..To compare three different methods of measuring corneal thickness (CT) and anterior chamber depth (ACD)...
  24. ncbi Comparison between GDx VCC scanning laser polarimetry and Stratus OCT optical coherence tomography in the diagnosis of chronic glaucoma
    Paolo Brusini
    Department of Ophthalmology, Santa Maria della Misericordia Hospital, Udine, Italy
    Acta Ophthalmol Scand 84:650-5. 2006
    ....
  25. ncbi Agreement and repeatability of central thickness measurement in normal corneas using ultrasound pachymetry and the OCULUS Pentacam
    Clare O'Donnell
    Faculty of Life Sciences, The University of Manchester, UK
    Cornea 24:920-4. 2005
    ..To compare the accuracy and repeatability of the OCULUS Pentacam (a new Scheimpflug-based imaging system) with ultrasound pachymetry in the measurement of central corneal thickness (CCT)...
  26. ncbi Optical coherence tomography imaging of the anterior chamber angle
    Sunita Radhakrishnan
    Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmol Clin North Am 18:375-81, vi. 2005
    ..It has the potential for use as a rapid screening tool for detection of occludable angles. Ongoing clinical studies should help to evaluate its efficacy in this regard...
  27. ncbi Repeatability and reproducibility of central corneal thickness measurement with Pentacam, Orbscan, and ultrasound
    Birgit Lackner
    Department of Ophthalmology, Medical University of Vienna, Vienna, Austria
    Optom Vis Sci 82:892-9. 2005
    ....
  28. ncbi Diagnostic ability of optical coherence tomography with a normative database to detect localized retinal nerve fiber layer defects
    Jin Wook Jeoung
    Department of Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea
    Ophthalmology 112:2157-63. 2005
    ..To evaluate the diagnostic ability of third-generation optical coherence tomography (Stratus OCT) with a normative database to detect localized retinal nerve fiber layer (RNFL) defects...
  29. ncbi Test-retest variability in structural and functional parameters of glaucoma damage in the glaucoma imaging longitudinal study
    Henry D Jampel
    Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Glaucoma 15:152-7. 2006
    ..To determine the test-retest variability in perimetric, optic disc, and macular thickness parameters in a cohort of treated patients with established glaucoma...
  30. ncbi Reduction of posterior pole retinal thickness in glaucoma detected using the Retinal Thickness Analyzer
    Masaki Tanito
    Sensho kai Eye Institute, Kyoto, Japan
    Ophthalmology 111:265-75. 2004
    ..To report evidence of changes in posterior pole retinal thickness in glaucoma and preperimetric glaucoma...
  31. ncbi Sensitivity and specificity of the StratusOCT for perimetric glaucoma
    Donald L Budenz
    Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, Miami, Florida 33136, USA
    Ophthalmology 112:3-9. 2005
    ..To determine the sensitivity and specificity of measurements of the retinal nerve fiber layer (RNFL) using the StratusOCT in glaucoma subjects with visual field (VF) defects...
  32. ncbi Enhanced imaging algorithm for scanning laser polarimetry with variable corneal compensation
    Nicolaas J Reus
    Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
    Invest Ophthalmol Vis Sci 47:3870-7. 2006
    ..To describe and investigate a method of improving assessment of retinal nerve fiber layer (RNFL) morphology with scanning laser polarimetry (SLP) with variable corneal compensation (VCC)...
  33. ncbi Evaluation of retinal nerve fiber layer, optic nerve head, and macular thickness measurements for glaucoma detection using optical coherence tomography
    Felipe A Medeiros
    Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, California 92093 0946, USA
    Am J Ophthalmol 139:44-55. 2005
    ..To compare the ability of optical coherence tomography retinal nerve fiber layer (RNFL), optic nerve head, and macular thickness parameters to differentiate between healthy eyes and eyes with glaucomatous visual field loss...
  34. ncbi Quantitative assessment of atypical birefringence images using scanning laser polarimetry with variable corneal compensation
    Harmohina Bagga
    Department of Ophthalmology, University of Miami School of Medicine, Bascom Palmer Eye Institute, Miami, Florida, USA
    Am J Ophthalmol 139:437-46. 2005
    ..To define the clinical characteristics of atypical birefringence images and to describe a quantitative method for their identification...
  35. ncbi Repeatability and validity of Zywave aberrometer measurements
    Willem J Hament
    Department of Ophthalmology, Academic Hospital Maastricht, P Debyelaan 25, 6202 AZ Maastricht, The Netherlands
    J Cataract Refract Surg 28:2135-41. 2002
    ..To study the repeatability of Zywave aberrometer (Bausch & Lomb) measurements and compare the measurements with those of subjective refraction and noncycloplegic and cycloplegic autorefractions in a clinical setting...
  36. ncbi Correlation between topographic profiles of localized retinal nerve fiber layer defects as determined by optical coherence tomography and red-free fundus photography
    Jeong Min Hwang
    Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul, Korea
    J Glaucoma 15:223-8. 2006
    ..To evaluate the topographic relationship of localized retinal nerve fiber layer (RNFL) defects as determined by optical coherence tomography (OCT) and by red-free fundus photography...
  37. ncbi Evaluation of enhanced corneal compensation in scanning laser polarimetry: comparison with variable corneal compensation on human eyes undergoing LASIK
    Marta Toth
    Department of Ophthalmology Semmelweis University, Budapest
    J Glaucoma 15:53-9. 2006
    ..To investigate the potential advantages of an enhanced corneal compensation algorithm (ECC) compared with variable corneal compensation (VCC), in scanning laser polarimetry...
  38. ncbi Agreement between stereoscopic photographs, clinical assessment, Heidelberg retina tomograph and digital stereoscopic optic disc camera in estimating vertical cup:disc ratio
    Thiran Jayasundera
    Department of Ophthalmology, University at Auckland, Auckland, New Zealand
    Clin Experiment Ophthalmol 33:259-63. 2005
    ....
  39. ncbi Comparative study of retinal nerve fiber layer measurement by StratusOCT and GDx VCC, I: correlation analysis in glaucoma
    Christopher Kai Shun Leung
    Department of Ophthalmology, Caritas Medical Centre, 111 Wing Hong Street, Sham Shui Po, Hong Kong, People s Republic of China
    Invest Ophthalmol Vis Sci 46:3214-20. 2005
    ..Dublin, CA) and GDx VCC (Laser Diagnostic Technologies, Inc., San Diego, CA)...
  40. ncbi Effect of corneal thickness on the agreement between ultrasound and Orbscan II pachymetry
    Hassan Hashemi
    Noor Ophthalmology Research Center, Tehran University of Medical Sciences, Tehran, Iran
    J Cataract Refract Surg 33:1694-700. 2007
    ..To study the agreement between ultrasound (US) and Orbscan II (Bausch & Lomb) measurements with different ranges of central thickness in normal corneas...
  41. pmc Comparison of anterior chamber depth measurements using the IOLMaster, scanning peripheral anterior chamber depth analyser, and anterior segment optical coherence tomography
    Raghavan Lavanya
    Glaucoma Department, Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751
    Br J Ophthalmol 91:1023-6. 2007
    ..Depth measurements were made from the corneal epithelium to the anterior lens surface. The values obtained were compared using Bland-Altman analysis...
  42. ncbi Comparison of central corneal thickness measurements by rotating Scheimpflug camera, ultrasonic pachymetry, and scanning-slit corneal topography
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Ophthalmology 113:937-41. 2006
    ..To compare central corneal thickness measurements and their reproducibility when taken by a rotating Scheimpflug camera, ultrasonic pachymetry, and scanning-slit corneal topography/pachymetry...
  43. pmc Optic disk and nerve fiber layer imaging to detect glaucoma
    Federico Badala
    Glaucoma Division, Jules Stein Eye Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA
    Am J Ophthalmol 144:724-32. 2007
    ..To compare optic disk and retinal nerve fiber layer (RNFL) imaging methods to discriminate eyes with early glaucoma from normal eyes...
  44. pmc Optic disk size and glaucoma
    Esther M Hoffmann
    Hamilton Glaucoma Center, Department of Ophthalmology, University of California, San Diego, La Jolla, CA 92093 0946, USA
    Surv Ophthalmol 52:32-49. 2007
    ..These disk size- dependent variations may influence the susceptibility to glaucoma or the likelihood of glaucoma diagnosis. This manuscript reviews the published evidence relating to disk size and glaucoma...
  45. pmc An enhancement module to improve the atypical birefringence pattern using scanning laser polarimetry with variable corneal compensation
    M Sehi
    PhD, Bascom Palmer Eye Institute, 7108 Fairway Drive, Suite 340, Palm Beach Gardens, FL 33418, USA
    Br J Ophthalmol 90:749-53. 2006
    ..To examine the repeatability and effect of an enhancement module on the severity of atypical birefringence patterns (ABP) using scanning laser polarimetery (SLP) with variable corneal compensation (VCC)...
  46. ncbi Agreement among 3 methods to measure corneal thickness: ultrasound pachymetry, Orbscan II, and Visante anterior segment optical coherence tomography
    Emmy Y M Li
    Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China
    Ophthalmology 114:1842-7. 2007
    ..To assess the agreement of central and paracentral corneal thickness measurements between ultrasound pachymetry (USP), Orbscan II, and Visante anterior segment optical coherence tomography (ASOCT)...
  47. ncbi Atypical pattern of retardation on GDx-VCC and its effect on retinal nerve fibre layer evaluation in glaucomatous eyes
    S Da Pozzo
    Eye Clinic, University of Trieste, Trieste, Italy
    Eye (Lond) 20:769-75. 2006
    ..To assess the effect of atypical pattern of retardation (APR) on retinal nerve fibre layer (RNFL) measurements made by scanning laser polarimetry (SLP) with variable corneal compensation (GDx-VCC) in glaucomatous eyes...
  48. ncbi Central corneal thickness measurements using Orbscan II, Visante, ultrasound, and Pentacam pachymetry after laser in situ keratomileusis for myopia
    Thomas Ho
    Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, University Eye Center, Hong Kong Eye Hospital, Hong Kong, China
    J Cataract Refract Surg 33:1177-82. 2007
    ..To compare corneal pachymetry assessment using 4 measurement methods in eyes after laser in situ keratomileusis (LASIK) for myopia...
  49. ncbi Validity and repeatability of anterior chamber depth measurements with Pentacam and Orbscan
    Birgit Lackner
    Department of Ophthalmology, Medical University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    Optom Vis Sci 82:858-61. 2005
    ....
  50. ncbi Scanning laser polarimetry using variable corneal compensation in the detection of glaucoma with localized visual field defects
    Michael S Kook
    Department of Ophthalmology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
    Ophthalmology 112:1970-8. 2005
    ..To evaluate the ability of scanning laser polarimetry parameters and a novel deviation map algorithm to discriminate between healthy and early glaucomatous eyes with localized visual field (VF) defects confined to one hemifield...
  51. ncbi Operator learning effect and interoperator reproducibility of the scanning laser polarimeter with variable corneal compensation
    Shahar Frenkel
    Department of Ophthalmology, Hebrew University Hadassah Medical Center, Jerusalem, Israel
    Ophthalmology 112:257-61. 2005
    ..To ascertain operator learning effect, and to quantify the interoperator reproducibility, using the newly introduced GDx VCC (variable corneal compensator) scanning laser polarimeter...
  52. doi QuantiFERON TB-Gold--a new test strengthening long-suspected tuberculous involvement in serpiginous-like choroiditis
    Friederike Mackensen
    Interdisciplinary Uveitis Center, Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany
    Am J Ophthalmol 146:761-6. 2008
    ..To obtain a diagnosis of tuberculosis in patients with a specific subset of uveitis, serpiginous-like choroiditis. This subset has been suspicious for tuberculous etiology in single case reports and old textbooks...
  53. ncbi Anterior chamber depth measurement: a-scan versus optical methods
    Gabor Koranyi
    St Erik s Eye Hospital, Department of Ophthalmology, Stockholm, Sweden
    J Cataract Refract Surg 28:243-7. 2002
    ..To evaluate methods of measuring anterior chamber depth (ACD) before and after cataract surgery...
  54. ncbi Corneal indentation during ultrasonic pachometry
    O D Solomon
    Department of Ophthalmology, Case Western Reserve School of Medicine, Cleveland, Ohio, USA
    Cornea 18:214-5. 1999
    ..This study attempted to determine whether the indentation of the cornea with an ultrasonic probe affects the corneal-thickness measurement...
  55. ncbi Reliability of pachymetric measurements using orbscan after excimer refractive surgery
    Olivier Prisant
    Fondation Ophtalmologique Adolphe de Rothschild, Hopital Bichat, 25 à 29 Rue Manin, 75019 Paris, France
    Ophthalmology 110:511-5. 2003
    ..To assess the accuracy of pachymetric measurements using Orbscan (Bausch & Lomb, Rochester, NY) after laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK)...
  56. ncbi Glaucoma detection using scanning laser polarimetry with variable corneal polarization compensation
    Robert N Weinreb
    Hamilton Glaucoma Center, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0946, USA
    Arch Ophthalmol 121:218-24. 2003
    ....
  57. ncbi Macular hole secondary to branch retinal vein occlusion diagnosed by Retinal Thickness Analyzer
    Igal Leibovitch
    Department of Ophthalmology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Ophthalmic Surg Lasers Imaging 34:53-6. 2003
    ..This article reports a patient with decreased vision following branch retinal vein occlusion in whom the Retinal Thickness Analyzer was used to establish the diagnosis of a macular lamellar hole that was not apparent clinically...
  58. ncbi Comparison of ultrasound pachymetry and partial coherence interferometry in the measurement of central corneal thickness
    Georg Rainer
    Department of Ophthalmology, University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    J Cataract Refract Surg 28:2142-5. 2002
    ..To compare central corneal thickness (CCT) measurements obtained with 3 ultrasound pachymeters and with partial coherence interferometry (PCI) and evaluate the effect of repeated contact by a pachymetry probe on corneal thickness...
  59. ncbi Correlational study of central corneal thickness measurements on Hong Kong Chinese using optical coherence tomography, Orbscan and ultrasound pachymetry
    A C M Wong
    Lo Ka Chow Memorial Ophthalmic Centre, Tung Wah Eastern Hospital, Hong Kong, PRC
    Eye (Lond) 16:715-21. 2002
    ..Central corneal thickness (CCT) of 74 eyes from 39 normal Hong Kong Chinese subjects with ages ranging from 39 to 86 years were studied...
  60. ncbi Individualized compensation of anterior segment birefringence during scanning laser polarimetry
    Qienyuan Zhou
    Laser Diagnostic Technologies, Inc, San Diego, California, USA
    Invest Ophthalmol Vis Sci 43:2221-8. 2002
    ..To describe a method for assessment and individualized compensation of anterior segment birefringence with scanning laser polarimetry...
  61. pmc Agreement in assessing optic discs with a digital stereoscopic optic disc camera (Discam) and Heidelberg retina tomograph
    Velota C T Sung
    Eye, Ear, Nose and Throat Centre, Queen s Medical Centre, University Hospital, Nottingham NG7 2UH, UK
    Br J Ophthalmol 86:196-202. 2002
    ....
  62. ncbi Comparison of optic nerve imaging methods to distinguish normal eyes from those with glaucoma
    Michael J Greaney
    Jules Stein Eye Institute, University of California Los Angeles Medical School, Los Angeles, California 90095 7000, USA
    Invest Ophthalmol Vis Sci 43:140-5. 2002
    ....
  63. ncbi Optic disc and visual field changes in a prospective longitudinal study of patients with glaucoma: comparison of scanning laser tomography with conventional perimetry and optic disc photography
    B C Chauhan
    Department of Ophthalmology, Dalhousie Iniversity, Halifax, Nova Scotia, Canada
    Arch Ophthalmol 119:1492-9. 2001
    ..To investigate the relationship between optic disc changes measured with scanning laser tomography and those measured with conventional perimetry and optic disc photography...
  64. ncbi Scanning-slit and specular microscopic pachymetry in comparison with ultrasonic determination of corneal thickness
    L Modis
    Medical and Health Science Center, Department of Ophthalmology, University of Debrecen, 98 Nagyerdei krt, H 4012 Debrecen, Hungary
    Cornea 20:711-4. 2001
    ....
  65. ncbi Assessment of the retinal nerve fiber layer in clinical trials of glaucoma neuroprotection
    E Z Blumenthal
    Glaucoma Center, University of California-San Diego, La Jolla, CA 92093-0946, USA
    Surv Ophthalmol 45:S305-12; discussion S332-4. 2001
    ..Nevertheless, there are excellent prospects for using longitudinal assessment of the RNFL in clinical trials of glaucoma neuroprotection...
  66. ncbi Comparison of data analysis tools for detection of glaucoma with the Heidelberg Retina Tomograph
    Bryce A Ford
    Department of Ophthalmology, Dalhousie University, Halifax, N S, Canada
    Ophthalmology 110:1145-50. 2003
    ..Furthermore, to investigate whether the classification of glaucomatous eyes is related to the severity of visual field loss or to optic disc size...
  67. ncbi Visualization of localized retinal nerve fiber layer defects with the GDx with individualized and with fixed compensation of anterior segment birefringence
    Nicolaas J Reus
    The Rotterdam Eye Hospital, Rotterdam, The Netherlands
    Ophthalmology 110:1512-6. 2003
    ....
  68. ncbi Comparison of different methods for detecting glaucomatous visual field progression
    Eija Vesti
    Discoveries in Sight, Devers Eye Institute, Portland, Oregon, USA
    Invest Ophthalmol Vis Sci 44:3873-9. 2003
    ..To compare the performance characteristics of seven methods for analyzing glaucomatous visual field progression, using a combination of real patient data and computer simulation techniques...
  69. ncbi Central corneal thickness measurement with Pentacam, Orbscan II, and ultrasound devices before and after laser refractive surgery for myopia
    Hassan Hashemi
    Farabi Eye Hospital, Department of Ophthalmology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Cataract Refract Surg 33:1701-7. 2007
    ....
  70. ncbi Ocular higher-order aberrations in individuals screened for refractive surgery
    Li Wang
    Cullen Eye Institute, Baylor College of Medicine, Department of Ophthalmology, Houston, Texas, USA
    J Cataract Refract Surg 29:1896-903. 2003
    ....
  71. ncbi Intraocular tuberculosis--an update
    Vishali Gupta
    Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Surv Ophthalmol 52:561-87. 2007
    ....
  72. ncbi Quantitative assessment of structural damage in eyes with localized visual field abnormalities
    Harmohina Bagga
    Department of Ophthalmology, University of Miami School of Medicine, Bascom Palmer Eye Institute, Miami, Florida, USA
    Am J Ophthalmol 137:797-805. 2004
    ....
  73. ncbi In vivo and in vitro repeatability of Hartmann-Shack aberrometry
    Alireza Mirshahi
    Department of Ophthalmology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Cataract Refract Surg 29:2295-301. 2003
    ..To assess the in vivo and in vitro repeatability of objective refraction and higher-order aberrations (HOAs) measured by a commercially available Hartmann-Shack wavefront sensor...
  74. ncbi Central corneal thickness measurements in unoperated eyes and eyes after PRK for myopia using Pentacam, Orbscan II, and ultrasonic pachymetry
    Sun Woong Kim
    Department of Ophthalmology, Soonchunhyang University College of Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea
    J Refract Surg 23:888-94. 2007
    ....
  75. ncbi Intraobserver reproducibility of retinal nerve fiber layer measurements using scanning laser polarimetry and optical coherence tomography in normal and ocular hypertensive subjects
    A Lleo-Perez
    Rahhal Ophthalmology Clinic Spain
    Eur J Ophthalmol 14:523-30. 2004
    ..To evaluate quantitatively the intraobserver reproducibility of measurements of the retinal nerve fiber layer (RNFL) in healthy subjects and an ocular hypertensive population using two nerve fiber analyzers...
  76. ncbi Influence of operator experience on the performance of ultrasound biometry compared to optical biometry before cataract surgery
    Oliver Findl
    Department of Ophthalmology, University of Vienna, Vienna, Austria
    J Cataract Refract Surg 29:1950-5. 2003
    ..To compare measurements performed with the IOLMaster (Carl Zeiss, Meditec AG) with those obtained by applanation ultrasound (US) and manual keratometry and to evaluate the effect of operator experience on US biometry...
  77. ncbi Comparison of central corneal thickness measured with Orbscan and Pentacam
    Nicola Rosa
    Eye Department, 2nd University of Naples, Naples, Italy
    J Refract Surg 23:895-9. 2007
    ..To compare central corneal thickness measurements obtained with Orbscan II using the acoustic equivalent correction factor (CF) and Pentacam in eyes screened for refractive surgery...
  78. ncbi Comparison of IOP measurements between ORA and GAT in normal Chinese
    Andrew Lam
    School of Optometry, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China
    Optom Vis Sci 84:909-14. 2007
    ..To compare intraocular pressure (IOP) obtained from the ocular response analyzer (ORA) and Goldmann applanation tonometer (GAT) on a group of normal Chinese...
  79. ncbi Association between intensity of posterior capsule opacification and visual acuity
    Wolf Buehl
    Department of Ophthalmology, Medical University of Vienna, Austria
    J Cataract Refract Surg 31:543-7. 2005
    ..To investigate the correlation between the change in visual acuity and the difference in objective posterior capsule opacification (PCO) scores before and after neodymium:YAG (Nd:YAG) laser capsulotomy...
  80. ncbi Wavefront technology in ophthalmology
    N Maeda
    Department of Ophthalmology, Osaka University Medical School, Osaka, Japan
    Curr Opin Ophthalmol 12:294-9. 2001
    ..In addition, it will be theoretically possible to obtain supernormal vision by wavefront-guided refractive surgery...
  81. ncbi Evaluation of refractive error measurements of the Wavescan Wavefront system and the Tracey Wavefront aberrometer
    Li Wang
    Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, 6565 Fannin, Houston, TX 77030, USA
    J Cataract Refract Surg 29:970-9. 2003
    ..To evaluate the accuracy and repeatability of the WaveScan WavePrint system and the Tracey wavefront aberrometer in measuring refractive errors in phakic eyes...
  82. ncbi Reproducibility and repeatability of central corneal thickness measurement in keratoconus using the rotating Scheimpflug camera and ultrasound pachymetry
    Ugo de Sanctis
    Department of Clinical Physiopathology, Ophthalmology Institute, University of Turin, Turin, Italy
    Am J Ophthalmol 144:712-718. 2007
    ..To assess repeatability, reproducibility, and agreement of rotating Scheimpflug camera (Pentacam Oculus, Wetzlar, Germany) and ultrasound pachymetry in measuring central thickness of keratoconic corneas...
  83. pmc Factors affecting the test-retest variability of Heidelberg retina tomograph and Heidelberg retina tomograph II measurements
    N G Strouthidis
    Glaucoma Research Unit, Moorfields Eye Hospital, 162 City Road, London EC1V 2PD, UK
    Br J Ophthalmol 89:1427-32. 2005
    ..An investigation into the factors affecting the repeatability of the measurements of this parameter(s) was conducted...
  84. ncbi Repeatability of ocular wavefront measurement
    Nigel Davies
    Department of Ophthalmology, The Middlesex Hospital, Mortimer Street, London, United Kingdom
    Optom Vis Sci 80:142-50. 2003
    ..To assess the repeatability of measurements of ocular aberrations using wavefront sensing in a small group of observers and to assess the potential effect of measurement error on custom corneal correction due to this variability...
  85. ncbi Glaucoma detection using different Stratus optical coherence tomography protocols
    Jesper Leth Hougaard
    Department of Clinical Sciences, Ophthalmology, Malmo University Hospital, Lund University, Malmo, Sweden
    Acta Ophthalmol Scand 85:251-6. 2007
    ..To examine and compare the diagnostic accuracy of retinal nerve fibre layer (RNFL) thickness measurements using different Stratus optical coherence tomography (OCT) scanning protocols...
  86. doi Retinal nerve fiber layer measurement repeatability in scanning laser polarimetry with enhanced corneal compensation
    Thê Anh Mai
    The Rotterdam Eye Hospital, Rotterdam, The Netherlands
    J Glaucoma 17:269-74. 2008
    ....
  87. ncbi Is scanning laser polarimetry ready for clinical practice?
    Robert N Weinreb
    Am J Ophthalmol 143:674-6. 2007
  88. ncbi Early glaucoma detection using the Humphrey Matrix Perimeter, GDx VCC, Stratus OCT, and retinal nerve fiber layer photography
    Samin Hong
    Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea
    Ophthalmology 114:210-5. 2007
    ..To compare the effectiveness of Humphrey Matrix perimetry, GDx VCC, Stratus OCT, and retinal nerve fiber layer (RNFL) photography using the Heidelberg Retina Angiograph 1 (HRA1) for early glaucoma detection...
  89. ncbi Diagnostic accuracy of the Moorfields Regression Analysis using the Heidelberg Retina Tomograph in glaucoma patients with visual field defects
    N Medved
    University Medical Centre, Eye Hospital Ljubljana, Zaloska 29a, 1525 Ljubljana, Slovenia
    Eur J Ophthalmol 17:216-22. 2007
    ..This study was designed to determine the specificity and sensitivity of the Heidelberg Retina Tomograph I (HRT) using the Moorfields Regression Analysis (MRA) in differentiating healthy from glaucomatous eyes...
  90. ncbi Using red-free monochromatic conversions of nonmydriatic digital fundus images
    Eui Seok Han
    Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea
    Am J Ophthalmol 143:371-2. 2007
    ..To compare three types of digital images for assessment of retinal nerve fiber layer (RNFL) defects: red-free RNFL images, color nonmydriatic images, and digitally converted nonmydriatic red-free fundus images...
  91. ncbi Diagnostic ability of Heidelberg Retina Tomograph 3 classifications: glaucoma probability score versus Moorfields regression analysis
    Antonio Ferreras
    Department of Ophthalmology, Miguel Servet University Hospital, Zaragoza, Spain
    Ophthalmology 114:1981-7. 2007
    ....
  92. ncbi The effect of disc size and severity of disease on the diagnostic accuracy of the Heidelberg Retina Tomograph Glaucoma Probability Score
    Linda M Zangwill
    Hamilton Glaucoma Center, Department of Ophthalmology, University of California, San Diego, CA 92093 0946, USA
    Invest Ophthalmol Vis Sci 48:2653-60. 2007
    ..To compare the effect of disc size and disease severity on the Heidelberg Retina Tomograph (HRT) Glaucoma Probability Score (GPS) and the Moorfields Regression Analysis (MRA) for discriminating between glaucomatous and healthy eyes...
  93. ncbi Accuracy of combined GDx-VCC and matrix FDT in a glaucoma screening trial
    Marta Toth
    Department of Ophthalmology, Semmelweis University, Budapest, Hungary
    J Glaucoma 16:462-70. 2007
    ..To assess the advantage in glaucoma screening of the use of scanning laser polarimetry with customized cornea compensation (GDx-VCC) combined with Matrix Frequency Doubling Technology (M-FDT) testing...
  94. pmc Relationship between scanning laser polarimetry with enhanced corneal compensation and with variable corneal compensation
    Kyung Hoon Kim
    Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea
    Korean J Ophthalmol 22:18-25. 2008
    ....
  95. pmc Comparison of retinal nerve fiber layer and optic disc imaging for diagnosing glaucoma in patients suspected of having the disease
    Felipe A Medeiros
    Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, CA 92093 0946, USA
    Ophthalmology 115:1340-6. 2008
    ..To compare retinal nerve fiber layer (RNFL) and optic disc topographic imaging for detection of optic nerve damage in patients suspected of having glaucoma...
  96. ncbi Diagnostic ability of the Heidelberg retina tomograph, optical coherence tomograph, and scanning laser polarimeter in open-angle glaucoma
    Victoria Pueyo
    Ophthalmology Department, Miguel Servet University Hospital, Zaragoza, Spain
    J Glaucoma 16:173-7. 2007
    ....
  97. ncbi Application of shape-based analysis methods to OCT retinal nerve fiber layer data in glaucoma
    Pinakin Gunvant
    Southern College of Optometry, Memphis, TN 38104 2222, USA
    J Glaucoma 16:543-8. 2007
    ..2) To compare the performance of the shape-based metrics to that of the standard OCT output measures (Inferior Average and Average Thickness)...
  98. pmc Optic disc imaging in perimetrically normal eyes of glaucoma patients with unilateral field loss
    Joseph Caprioli
    Jules Stein Eye Institute, Los Angeles, California, USA
    Trans Am Ophthalmol Soc 104:202-11. 2006
    ..To compare the ability of optic disc and retinal nerve fiber layer (RNFL) imaging to discriminate perimetrically unaffected eyes of glaucoma patients from normal eyes...
  99. ncbi Scanning laser polarimetry with enhanced corneal compensation and optical coherence tomography in normal and glaucomatous eyes
    Mitra Sehi
    Department of Ophthalmology, University of Miami Miller School of Medicine, Bascom Palmer Eye Institute, Palm Beach Gardens, Florida 33418, USA
    Invest Ophthalmol Vis Sci 48:2099-104. 2007
    ....
  100. ncbi Diagnostic accuracy of scanning laser polarimetry with enhanced versus variable corneal compensation
    T A Mai
    Rotterdam Eye Hospital, Rotterdam, The Netherlands
    Ophthalmology 114:1988-93. 2007
    ....
  101. ncbi Usefulness of optical coherence tomography parameters of the optic disc and the retinal nerve fiber layer to differentiate glaucomatous, ocular hypertensive, and normal eyes
    Alfonso Anton
    Instituto de Oftamobiología Aplicada, Universidad de Valladolid, Valladolid, Spain
    J Glaucoma 16:1-8. 2007
    ..To assess Stratus optical coherence tomography (OCT) original parameters for identifying glaucomatous damage and to evaluate differences among glaucomatous, ocular hypertensive, and normal eyes...

Research Grants62

  1. Noninvsive Imaging of Chorio-retinal Oxygen Tension
    Mahnaz Shahidi; Fiscal Year: 2005
    ..abstract_text> ..
  2. Telemedical Diagnosis of Retinopathy of Prematurity
    Michael Chiang; Fiscal Year: 2007
    ..Columbia University has a strong existing framework in medical information systems, telemedicine, and public health, which will be leveraged to complete this training and research program successfully. ..
  3. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Donald Budenz; Fiscal Year: 2008
    ....
  4. Retinal Image Quality in Retinal-diseased Eyes
    Mahnaz Shahidi; Fiscal Year: 2010
    ....
  5. OPTICAL AND RETINAL LIMITS TO HUMAN VISUAL PERFORMANCE
    Larry N Thibos; Fiscal Year: 2010
    ..Project 6. Develop a new concept of wavefront tomography to characterize the 3-dimensional structure of the eye's optical system from a series of wavefront measurements along multiple lines-of-sight. ..
  6. OUTCOME MEASURES FOR CLINICAL TRIALS IN STRABISMUS
    Jonathan Holmes; Fiscal Year: 2008
    ..Ultimately this research will result in better quality of life for patients with strabismus. ..
  7. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Robert Weinreb; Fiscal Year: 2008
    ....
  8. PATHOGENESIS OF RETINOPATHY OF PREMATURITY
    Jonathan Holmes; Fiscal Year: 2003
    ....
  9. EARLY DETECTION OF GLAUCOMA DAMAGE
    Henry Jampel; Fiscal Year: 2004
    ..This assessment of the RTA and NFA will help to establish their utility as outcome measures for clinical management of glaucoma, epidemiological research, and clinical trials. ..
  10. Gene Therapy of Autosomal Recessive RP
    Simon Petersen Jones; Fiscal Year: 2006
    ..abstract_text> ..
  11. COLLABORATIVE INITIAL GLAUCOMA TREATMENT STUDY
    Henry Jampel; Fiscal Year: 2002
    ....
  12. GLAUCOMA SURGICAL OUTCOMES STUDY
    Henry Jampel; Fiscal Year: 2001
    ..The results of the study may allow physicians to reduce the morbidity of glaucoma surgery by altering their indications for surgery, surgical technique, and postoperative follow-up. ..
  13. Eicosanoids and the Outflow Pathways of the Eye
    Robert Weinreb; Fiscal Year: 2008
    ..The results of these studies have important implications for the discovery of new treatments for glaucoma and other vision-threatening eye diseases. ..
  14. An Internet Based Imaging System for Practical Diabetic*
    Ingrid Zimmer Galler; Fiscal Year: 2007
    ..We will lay the concepts and specifications for a computer based training program for education, certification and quality control of readers. [unreadable] [unreadable] [unreadable]..
  15. Characterization of Tear Dynamics
    Jianhua Wang; Fiscal Year: 2007
    ..g. dry eye). [unreadable] [unreadable]..
  16. Retinal Vascular Changes in Type 1 Diabetic African-Americans
    Monique Roy; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  17. Treatment for Canine Diabetic Cataracts
    Milton Wyman; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  18. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    David Herman; Fiscal Year: 2008
    ..Documentation is provided of the capabilities of the proposed investigators and their staff for the performance of the study in accord with the details of the OHTS Manual of Procedures." ..
  19. VESTIBULAR INFLUENCES ON SPATIAL ORIENTATION
    Richard Lewis; Fiscal Year: 2008
    ..abstract_text> ..
  20. Ethnic Disparities in Diabetes Complications
    Andrew Karter; Fiscal Year: 2008
    ..abstract_text> ..
  21. Mechanisms of apoptosis in the central nervous system
    Kenneth Tyler; Fiscal Year: 2009
    ..In addition, the proposed studies will evaluate the role of these genes and pathways as novel therapeutic targets for these diseases. ..
  22. Mechanisms of virus-induced apoptosis in neurons and CNS
    Kenneth L Tyler; Fiscal Year: 2010
    ..pathways involved, as well as an easily accessible in mouse model of CNS apoptosis that allows rapid testing of results obtained in cell culture for their significance on the pathogenesis of CNS viral disease in vivo ..
  23. PATHOGENESIS OF GLAUCOMATOUS OPTIC NERVE DAMAGE
    Harry Quigley; Fiscal Year: 2008
    ..Candidate molecules for genetic susceptibility to glaucoma are likely to be identified. ..
  24. Ultrasound-Enhanced Delivery of Medications to the Eye
    Ronald Silverman; Fiscal Year: 2008
    ..We will visualize the distribution of the molecules within the sclera, choroid and retina to evaluate transport and characterize any tissue damage that might have occurred microscopically and by apoptosis assays. ..
  25. VISION RESEARCH AT INDIANA UNIVERSITY
    Joseph Bonanno; Fiscal Year: 2008
    ..They include advanced optics of the eye, visual displays for infant vision development, microscopic fluorimetry and imaging, and equipment repair support. [unreadable] [unreadable] [unreadable]..
  26. Low-cost, portable, computer assisted imaging for diabe*
    Michael Abramoff; Fiscal Year: 2008
    ..Our overall aim is to validate and optimize a low-cost, high quality, patient friendly imaging system for the early diagnosis of diabetic retinopathy. ..
  27. Novel Risk Factors for Chronic Kidney Disease
    Ronald Klein; Fiscal Year: 2008
    ..The new data may provide insights into the relative protective value of low levels of these markers on the incidence CKD in an aging population. [unreadable] [unreadable] [unreadable]..
  28. Diagnostic Innovations in Glaucoma: Clinical Electrophysiology
    Christopher Bowd; Fiscal Year: 2008
    ..Findings will be important to the clinical community for determining future evidence-based changes in standard of care for glaucoma diagnosis and monitoring. [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  29. Low-Cost Device for Digital Retinal Imaging
    Ann E Elsner; Fiscal Year: 2010
    ..While this project focuses on diabetic retinopathy in humans, future applications include other retinal disorders in both humans and animal models. ..
  30. CONVERGENCE INSUFFICIENCY TREATMENT TRIAL
    Rachel Coulter; Fiscal Year: 2006
    ....
  31. High Resolution and High Contrast Near-IR Imaging of the Human Fundus
    Nathan Doble; Fiscal Year: 2006
    ..Under this proposal, new imaging technology will be developed to fight debilitating eye disease resulting in earlier disease detection, faster drug clinical trials, and better medical understanding. [unreadable] [unreadable] [unreadable]..
  32. Prednisone Ocular Myasthenia Gravis Trial Planning Grant
    Mark Kupersmith; Fiscal Year: 2004
    ....
  33. RISK FACTORS FOR DIABETIC RETINOPATHY IN BLACK AMERICANS
    Monique Roy; Fiscal Year: 2003
    ..abstract_text> ..
  34. MODULATION OF CORTICAL ACTIVITY BY EYE MOVEMENTS
    D Snodderly; Fiscal Year: 2002
    ..The results will be relevant to human visual perception, as well as in vivo imaging of human visual function. ..
  35. Retinal Microvascular Characteristics/Vascular Disorders
    Ronald Klein; Fiscal Year: 2003
    ..abstract_text> ..
  36. HIGH-RESOLUTION IMAGING OF OCULAR MELANOMA AND RETINA
    Dirk Uwe Bartsch; Fiscal Year: 2003
    ..Since we can measure and characterize these aberrations, we can develop digital inverse filter based on our experience in image reconstruction to correct the acquired images. ..
  37. CONTACT LENSES AND MYOPIA (CLAMP) STUDY
    JEFFREY WALLINE; Fiscal Year: 2003
    ..The CLAMP Study is the ideal scope and size of study to train Dr. Walline to become an independent investigator and has the potential to change the standard of care for young children who become nearsighted. ..
  38. Do Free Glucose Test Strips Increase Self-Monitoring?
    Andrew Karter; Fiscal Year: 2003
    ..Proposal strengths also include a longitudinal design, substantial statistical power, low cost data acquisition, and an ethnically diverse population with uniform access to care. ..
  39. Ophthalmic Antibiotic Resistance Study
    Kirk Wilhelmus; Fiscal Year: 2003
    ..abstract_text> ..
  40. MEIBOMIAN KERATOCONJUNCTIVITIS
    James McCulley; Fiscal Year: 2003
    ..Methods include non-destructive HPLC as well as GC-MS to analyze patient meibum, and standard lipid mixtures based on the composition of patient meibum for physical measurements. ..
  41. RETINAL ARTERIOLAR ABNORMALITIES AND CV MORTALITY
    Ronald Klein; Fiscal Year: 2002
    ..Data from this study will improve the understanding of the association between microvascular characteristics and cardiovascular mortality. ..
  42. CORNEAL METABOLIC ACTIVITY IN HUMANS
    Joseph Bonanno; Fiscal Year: 2002
    ..If so, this could lead to the development of a provocative test for suitability of contact lens wear based on a quick and simple measure of corneal oxygen consumption. ..
  43. Central Scotomas in AMD and Cortical Remapping
    Janet Sunness; Fiscal Year: 2005
    ....
  44. CYTOKINE MODULATION IN PROLIFERATIVE VITREORETINOPATHY
    GLENN JAFFE; Fiscal Year: 2005
    ..Density-dependent effects of IL-1, TNFalpha, and specific NF-kappaB inhibitors on NF-kappaB-mediated RPE apoptosis will be quantified. IV) To determine whether specific in vivo NF-kappaB blockade inhibits PVR. ..
  45. Medical Advice from Glaucoma Informatics (MAGI)
    Michael Goldbaum; Fiscal Year: 2005
    ..In an effort to discover new and use useful information with unsupervised learning, we will mine our data in visual function and structural tests for glaucoma and in specific combinations of population groups. ..
  46. Microvascular - Macrovascular Disease in Type 2 Diabetes
    Ronald Klein; Fiscal Year: 2005
    ....
  47. Regulatory Role of CTL-O2/Bcl2 in Epithelial Homeostasis
    H Cavanagh; Fiscal Year: 2006
    ..abstract_text> ..
  48. Quan11tification of Glaucomatous Optic Neuropathy
    Christopher Girkin; Fiscal Year: 2006
    ....
  49. Multi-Ethnic Study of Atherosclerosis-Eye Study
    Ronald Klein; Fiscal Year: 2005
    ..insights into the relative contribution of microvascular disease to the pathophysiology and natural history of subclinical and clinical cardiovascular disease, in representative populations of men and women of diverse ethnicities ..
  50. Educational Disparities in Diabetes Complications
    Andrew Karter; Fiscal Year: 2006
    ..abstract_text> ..
  51. Retinopathy in Chronic Renal Insufficiency
    Juan E Grunwald; Fiscal Year: 2010
    ....
  52. Very-High-Frequency Ultrasound Imaging With Coded Signals and Annular Arrays
    Jonathan Mamou; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  53. Tailored messages to increase eye examination behavior
    NANCY ELLISH; Fiscal Year: 2007
    ..This proposal addresses the need for research to assess tailored print communications to increase eye examination behavior in a minority population at increased risk for glaucoma. ..
  54. Organization of the Trichromatic Cone Mosaic
    Joseph Carroll; Fiscal Year: 2005
    ..This will be done in subjects for whom we also have a representation of their cone mosaic, to be able to selectively stimulate cones from a particular class. ..
  55. Conformal laser thermal therapy for epithelial cancer
    Brett Bouma; Fiscal Year: 2007
    ....
  56. Choroidal circulation in age related macular degeneration
    Juan Grunwald; Fiscal Year: 2008
    ..In addition, the knowledge gained through this investigation could also help in the identification of patients at risk of developing choroidal neovascularization, thus enabling earlier treatment. [unreadable] [unreadable] [unreadable]..
  57. OCULAR HEMODYNAMICS IN GLAUCOMA
    Juan Grunwald; Fiscal Year: 2001
    ..If hemodynamic abnormalities are present, then attention can be focused on altering the optic nerve circulation as a means of treating glaucoma. ..
  58. In-site Measurement of Plaque Biomechanical Properties
    Brett Bouma; Fiscal Year: 2005
    ..The methods that will be developed in this work present the potential for characterizing the biomechanical properties of coronary plaques in vivo and may facilitate the development of improved therapeutic approaches. ..
  59. The Northwest Tribal Vision Project
    Steven Mansberger; Fiscal Year: 2008
    ..This project will then lead to a larger, more comprehensive survey of the prevalence and causes of visual impairment in AI/AN. ..
  60. Optical modeling of visual corrections
    Pete Kollbaum; Fiscal Year: 2008
    ..These models will have general applicability to other diseased conditions in which visual performance is degraded due to increased optical aberrations. [unreadable] [unreadable]..
  61. Low-Cost Device for Digital Retinal Imaging
    ANN ELSNER; Fiscal Year: 2007
    ..We will investigate the key features considered necessary for early detection grading, and also more the serious damage that is typically discovered late in the rural and urban underserved. ..