cortical synchronization

Summary

Top Publications

  1. ncbi Event-related synchronization (ERS) in the alpha band--an electrophysiological correlate of cortical idling: a review
    G Pfurtscheller
    Department of Medical Informatics, Graz University of Technology, Austria
    Int J Psychophysiol 24:39-46. 1996
  2. pmc Licking-induced synchrony in the taste-reward circuit improves cue discrimination during learning
    Ranier Gutierrez
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 30:287-303. 2010
  3. pmc Gamma rhythms and beta rhythms have different synchronization properties
    N Kopell
    Department of Mathematics, Boston University, Boston MA 02215, USA
    Proc Natl Acad Sci U S A 97:1867-72. 2000
  4. ncbi What does phase information of oscillatory brain activity tell us about cognitive processes?
    Paul Sauseng
    Department of Psychology, University of Salzburg, Hellbrunnerstr 34, A 5020 Salzburg, Austria
    Neurosci Biobehav Rev 32:1001-13. 2008
  5. ncbi Neural synchrony in brain disorders: relevance for cognitive dysfunctions and pathophysiology
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstrasse 46, Frankfurt am Main, 60528, Germany
    Neuron 52:155-68. 2006
  6. pmc Neurophysiological and computational principles of cortical rhythms in cognition
    Xiao Jing Wang
    Department of Neurobiology and Kavli Institute of Neuroscience, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Physiol Rev 90:1195-268. 2010
  7. ncbi Fluctuations in cortical synchronization in pediatric traumatic brain injury
    Vera Nenadovic
    Critical Care Medicine Program, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
    J Neurotrauma 25:615-27. 2008
  8. ncbi Cross-regional cortical synchronization during affective image viewing
    Vladimir Miskovic
    McMaster Integrative Neuroscience Discovery and Study, McMaster University, 1280 Main Street West, Hamilton, ON, Canada L8S 4K1
    Brain Res 1362:102-11. 2010
  9. ncbi Large-scale gamma-band phase synchronization and selective attention
    Sam M Doesburg
    Psychophysics and Cognitive Neuroscience Laboratory, Department of Psychology, University of British Columbia, Vancouver V6T 1Z4, Canada
    Cereb Cortex 18:386-96. 2008
  10. ncbi The role of neuronal synchronization in selective attention
    Thilo Womelsdorf
    FC Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Kapittelweg 29, 6525 EN Nijmegen, The Netherlands
    Curr Opin Neurobiol 17:154-60. 2007

Research Grants

Detail Information

Publications259 found, 100 shown here

  1. ncbi Event-related synchronization (ERS) in the alpha band--an electrophysiological correlate of cortical idling: a review
    G Pfurtscheller
    Department of Medical Informatics, Graz University of Technology, Austria
    Int J Psychophysiol 24:39-46. 1996
    ..In both circumstances, the neurons in the hand area are not needed for visual processing or preparation for foot movement. As a result of this, an enhanced hand area mu rhythm can be observed...
  2. pmc Licking-induced synchrony in the taste-reward circuit improves cue discrimination during learning
    Ranier Gutierrez
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 30:287-303. 2010
    ....
  3. pmc Gamma rhythms and beta rhythms have different synchronization properties
    N Kopell
    Department of Mathematics, Boston University, Boston MA 02215, USA
    Proc Natl Acad Sci U S A 97:1867-72. 2000
    ..The synchronization properties are consistent with data suggesting that gamma rhythms are used for relatively local computations whereas beta rhythms are used for higher level interactions involving more distant structures...
  4. ncbi What does phase information of oscillatory brain activity tell us about cognitive processes?
    Paul Sauseng
    Department of Psychology, University of Salzburg, Hellbrunnerstr 34, A 5020 Salzburg, Austria
    Neurosci Biobehav Rev 32:1001-13. 2008
    ....
  5. ncbi Neural synchrony in brain disorders: relevance for cognitive dysfunctions and pathophysiology
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstrasse 46, Frankfurt am Main, 60528, Germany
    Neuron 52:155-68. 2006
    ..Thus, focused search for abnormalities in temporal patterning may be of considerable clinical relevance...
  6. pmc Neurophysiological and computational principles of cortical rhythms in cognition
    Xiao Jing Wang
    Department of Neurobiology and Kavli Institute of Neuroscience, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Physiol Rev 90:1195-268. 2010
    ..Finally, implications of abnormal neural synchronization are discussed as they relate to mental disorders like schizophrenia and autism...
  7. ncbi Fluctuations in cortical synchronization in pediatric traumatic brain injury
    Vera Nenadovic
    Critical Care Medicine Program, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
    J Neurotrauma 25:615-27. 2008
    ..74) better than the worst Glasgow Coma Scale score, length of coma, or extent of injury on CT scan. This represents a novel approach in the evaluation of TBI in children...
  8. ncbi Cross-regional cortical synchronization during affective image viewing
    Vladimir Miskovic
    McMaster Integrative Neuroscience Discovery and Study, McMaster University, 1280 Main Street West, Hamilton, ON, Canada L8S 4K1
    Brain Res 1362:102-11. 2010
    ..Our results suggest large-scale synchronization of cortical cells during affective viewing and emphasize the role of beta oscillations in mediating such binding...
  9. ncbi Large-scale gamma-band phase synchronization and selective attention
    Sam M Doesburg
    Psychophysics and Cognitive Neuroscience Laboratory, Department of Psychology, University of British Columbia, Vancouver V6T 1Z4, Canada
    Cereb Cortex 18:386-96. 2008
    ....
  10. ncbi The role of neuronal synchronization in selective attention
    Thilo Womelsdorf
    FC Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Kapittelweg 29, 6525 EN Nijmegen, The Netherlands
    Curr Opin Neurobiol 17:154-60. 2007
    ..These results point to a general computational role for selective synchronization in dynamically controlling which neurons communicate information about sensory inputs effectively...
  11. ncbi Event-related beta desynchronization indicates timing of response selection in a delayed-response paradigm in humans
    J Kaiser
    MEG Center, Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, Gartenstrasse 29, 72074 Tubingen, Germany
    Neurosci Lett 312:149-52. 2001
    ..This suggests a close relationship between the latency of beta ERD onset and the duration of cognitive processes involved in selecting a motor response...
  12. ncbi Changes in the alpha and beta amplitudes of the central EEG during the onset, continuation, and offset of long-duration repetitive hand movements
    Nurhan Erbil
    Hacettepe University, Faculty of Medicine, Department of Biophysics, Ankara, Turkey
    Brain Res 1169:44-56. 2007
    ..Modulation of the beta amplitude, rather than the changes in alpha amplitude, appeared to be more closely correlated with the execution of a continuous movement...
  13. ncbi Spectra-temporal patterns underlying mental addition: an ERP and ERD/ERS study
    Yixuan Ku
    Department of Biomedical Engineering, Medical School, Tsinghua University, 1 Qinghuayuan, Haidian District, Beijing 100084, China
    Neurosci Lett 472:5-10. 2010
    ..These results coincide with the theory of simple calculation relying on the visuospatial process and complex calculation depending on the phonological process...
  14. ncbi Phase synchrony among neuronal oscillations in the human cortex
    J Matias Palva
    Department of Biological and Environmental Sciences, University of Helsinki, FIN 00014 Helsinki, Finland
    J Neurosci 25:3962-72. 2005
    ..The enhancement of cross-frequency phase synchrony among functionally and spatially distinct networks during mental arithmetic tasks posits it as a candidate mechanism for the integration of spectrally distributed processing...
  15. ncbi Decreased neuronal synchronization during experimental seizures
    Theoden I Netoff
    Krasnow Institute for Advanced Studies, George Mason University, Fairfax, Virginia 22030, USA
    J Neurosci 22:7297-307. 2002
    ....
  16. ncbi Impaired consciousness during temporal lobe seizures is related to increased long-distance cortical-subcortical synchronization
    Marie Arthuis
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille, F 13005, France
    Brain 132:2091-101. 2009
    ..We suggest that excessive synchronization overloads the structures involved in consciousness processing, preventing them from treating incoming information, thus resulting in LOC...
  17. ncbi The role of corticothalamic coupling in human temporal lobe epilepsy
    Maxime Guye
    Service de Neurophysiologie Clinique, Unité Epilepsy and Cognition INSERM U751, CHU Timone et Université de la Méditerranée, Marseille, France
    Brain 129:1917-28. 2006
    ....
  18. ncbi Long-term modifications in motor cortical dynamics induced by intensive practice
    Bjørg E Kilavik
    Institut de Neurosciences Cognitives de la Méditerranée Centre National de la Recherche Scientifique, Universite Aix Marseille, 13402 Marseille, France
    J Neurosci 29:12653-63. 2009
    ..Performance optimization through practice might therefore be achieved by boosting the computational contribution of spike synchrony, allowing an overall reduction in population activity...
  19. ncbi Dynamics of spiking neurons connected by both inhibitory and electrical coupling
    Timothy J Lewis
    Center for Neural Science and Courant Institute for Mathematical Science, New York University, 4 Washington Place, Rm 809, NY 10003, USA
    J Comput Neurosci 14:283-309. 2003
    ..We also show that these results extend to moderate coupling strengths...
  20. ncbi Synchrony-dependent propagation of firing rate in iteratively constructed networks in vitro
    Alex D Reyes
    Center for Neural Science, New York University, 4 Washington Place, New York, New York 10003, USA
    Nat Neurosci 6:593-9. 2003
    ..The firing rate was represented by a classical rate code in the initial layers, but switched to a synchrony-based code in the deeper layers...
  21. ncbi Statistical method for detection of phase-locking episodes in neural oscillations
    Jose M Hurtado
    Center for Neuroscience, University of California, Davis, California 95616, USA
    J Neurophysiol 91:1883-98. 2004
    ..Surrogate methods that preserve the temporal structure of the individual phase time series decrease substantially the number of false positives when tested on a pair of independent signals...
  22. ncbi Existing motor state is favored at the expense of new movement during 13-35 Hz oscillatory synchrony in the human corticospinal system
    Thomas Gilbertson
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London WC1N 3BG, United Kingdom
    J Neurosci 25:7771-9. 2005
    ..The findings are of relevance to Parkinson's disease, in which subcortical and cortical beta-band synchronization is exaggerated in the setting of increased tone and slowed movements...
  23. ncbi Greater frontal-parietal synchrony at low gamma-band frequencies for inefficient than efficient visual search in human EEG
    Steven Phillips
    Neuroscience Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba Central 2, 1 1 1 Umezono, Tsukuba, Ibaraki 305 8568 Japan
    Int J Psychophysiol 73:350-4. 2009
    ..The failure to observe a bottom-up effect may be due to stimulus familiarity - monkeys require weeks of training in contrast to the few minutes given to humans...
  24. ncbi Defective cortical drive to muscle in Parkinson's disease and its improvement with levodopa
    Stephan Salenius
    Brain Research Unit, Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland
    Brain 125:491-500. 2002
    ..Abnormalities in this aspect of basal ganglia function may directly contribute to bradykinesia and weakness in Parkinson's disease...
  25. ncbi A high performance sensorimotor beta rhythm-based brain-computer interface associated with human natural motor behavior
    Ou Bai
    Human Motor Control Section, Medical Neurological Branch, National Institute of Neurological Disorders, National Institutes of Health, Bethesda, MD 20892, USA
    J Neural Eng 5:24-35. 2008
    ..The sensorimotor beta rhythm of EEG associated with human natural motor behavior can be used for a reliable and high performance BCI for both healthy subjects and patients with neurological disorders...
  26. ncbi Global and local synchrony of coupled neurons in small-world networks
    Naoki Masuda
    Faculty of Engineering, Yokohama National University, Yokohama, Japan
    Biol Cybern 90:302-9. 2004
    ..Finally, cooperation of the global connections and the local clustering property, which is prominent in small-world networks, forces synchrony of distant neuronal groups receiving coherent inputs...
  27. ncbi Early onset of post-movement beta electroencephalogram synchronization in the supplementary motor area during self-paced finger movement in man
    G Pfurtscheller
    Department of Medical Informatics, Institute of Biomedical Engineering, University of Technology Graz, Inffeldgasse 16a, A 8010, Graz, Austria
    Neurosci Lett 339:111-4. 2003
    ..This assumed resetting or inhibitory process within the SMA precedes that of the networks within the primary motor hand area...
  28. ncbi Nonlinear synchronization in EEG and whole-head MEG recordings of healthy subjects
    Cornelis J Stam
    Department of Clinical Neurophysiology, VU University Medical Centre, Amsterdam, The Netherlands
    Hum Brain Mapp 19:63-78. 2003
    ..The spatial scale and physical properties of MEG acquisition may increase the sensitivity of the data to underlying nonlinear structure...
  29. ncbi Postnatal differentiation of basket cells from slow to fast signaling devices
    Daniel Doischer
    Physiologisches Institut I, Universitat Freiburg, D 79104 Freiburg, Germany
    J Neurosci 28:12956-68. 2008
    ..Thus, late postnatal maturation of BCs enhances coherence in neuronal networks and will thereby contribute to the development of cognitive brain functions...
  30. ncbi Theta synchronization and alpha desynchronization in a memory task
    W Klimesch
    Department of Physiological Psychology, University of Salzburg, Austria
    Psychophysiology 34:169-76. 1997
    ..In contrast to the theta band, remembered and not remembered words revealed a complex pattern of desynchronization in the lower and upper alpha band that was different during encoding and recognition...
  31. ncbi Impaired functional connectivity at EEG alpha and theta frequency bands in major depression
    Andrew A Fingelkurts
    BM Science Brain and Mind Technologies Research Centre, Espoo, Finland
    Hum Brain Mapp 28:247-61. 2007
    ..This finding was interpreted within the semantic framework, where different specialization of left (monosemantic context) and right (polysemantic context) hemispheres is functionally insufficient in patients with depression...
  32. pmc Cortical abnormalities in epilepsy revealed by local EEG synchrony
    C A Schevon
    Department of Neurology, Columbia University Medical Center, NY, USA
    Neuroimage 35:140-8. 2007
    ....
  33. ncbi Small-world networks and functional connectivity in Alzheimer's disease
    C J Stam
    Department of Clinical Neurophysiology, VU University Medical Center, 1007 MB Amsterdam, The Netherlands
    Cereb Cortex 17:92-9. 2007
    ..Graph theoretical analysis may be a useful approach to study the complexity of patterns of interrelations between EEG channels...
  34. ncbi Alpha and beta oscillatory changes during stimulus-induced movement paradigms: effect of stimulus predictability
    Manuel Alegre
    Department of Neurology, Clinica Universitaria, Facultad de Medicina, Universidad de Navarra, Pamplona, Spain
    Neuroreport 14:381-5. 2003
    ..The minimal differences observed in the alpha changes in both paradigms suggest that alpha-ERD may not be linked to motor preparation...
  35. ncbi Noninvasive brain stimulation with low-intensity electrical currents: putative mechanisms of action for direct and alternating current stimulation
    Soroush Zaghi
    Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neuroscientist 16:285-307. 2010
    ..Here the authors review what is known about DC and AC stimulation, and they discuss features that remain to be investigated...
  36. ncbi Does post-movement beta synchronization reflect an idling motor cortex?
    F Cassim
    Departments of Clinical Neurophysiology and 1Neurology, Hopital Salengro, CHU, F 59037 Lille, France
    Neuroreport 12:3859-63. 2001
    ..Post-movement beta synchronization can not solely be explained by an idling motor cortex. It may also, at least in part, reflect a movement-related somatosensory processing...
  37. ncbi Phase synchronization measurements using electroencephalographic recordings: what can we really say about neuronal synchrony?
    Ramon Guevara
    Abdus Salam ICTP, Strada Costiera 11, 34100, Miaramare, Trieste, Italy
    Neuroinformatics 3:301-14. 2005
    ....
  38. ncbi Deep brain stimulation of the posterior hypothalamus activates the histaminergic system to exert antiepileptic effect in rat pentylenetetrazol model
    Namiko Nishida
    Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto 606 8507, Japan
    Exp Neurol 205:132-44. 2007
    ..This study clearly indicates that EEG desynchronization and the activation of the histaminergic system contributed to the antiepileptic effects caused by DBS to the posterior hypothalamus...
  39. ncbi EEG and FMRI coregistration to investigate the cortical oscillatory activities during finger movement
    Emanuela Formaggio
    Section of Neurological Rehabilitation, Department of Neurological and Visual Sciences, Gianbattista Rossi Hospital, University of Verona, P le Scuro, 37134, Verona, Italy
    Brain Topogr 21:100-11. 2008
    ....
  40. ncbi Motor imagery and EEG-based control of spelling devices and neuroprostheses
    Christa Neuper
    Institute of Psychology, University of Graz, Universitätsplatz 2 III, A 8010 Graz, Austria
    Prog Brain Res 159:393-409. 2006
    ..The major frequency bands of cortical oscillations considered here are the 8-13 and 15-30 Hz bands. This chapter describes the basic methods used in Graz-BCI research and outlines possible clinical applications...
  41. pmc Theta band zero-lag long-range cortical synchronization via hippocampal dynamical relaying
    Leonardo L Gollo
    Instituto de Física Interdisciplinar y Sistemas Complejos CSIC UIB, Campus Universitat de les Illes Balears, Palma de Mallorca, Spain
    PLoS ONE 6:e17756. 2011
    ..These results suggest that zero-lag long-range cortico-cortical synchronization is likely mediated by hippocampal theta oscillations in lower mammals as a function of cognitive demands ..
  42. ncbi Across-trial averaging of event-related EEG responses and beyond
    A Mouraux
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, United Kingdom
    Magn Reson Imaging 26:1041-54. 2008
    ..In addition, we provide practical guidelines on the implementation of these methods and on the interpretation of the results they produce...
  43. ncbi Alpha and beta oscillatory activity during a sequence of two movements
    Manuel Alegre
    Clinical Neurophysiolgy Section, Department of Neurology, Clinica Universitaria, Facultad de Medicina, Universidad de Navarra, Avda, Pio XII, 36, 31008 Pamplona, Spain
    Clin Neurophysiol 115:124-30. 2004
    ....
  44. pmc Synchronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety
    Avishek Adhikari
    Department of Biological Sciences, Columbia University, New York, NY 10032, USA
    Neuron 65:257-69. 2010
    ..They are consistent with the notion that such synchronization is a general mechanism by which the hippocampus communicates with downstream structures of behavioral relevance...
  45. pmc Auditory steady state response in bipolar disorder: relation to clinical state, cognitive performance, medication status, and substance disorders
    Olga Rass
    Department of Psychological and Brain Sciences, Indiana University, 101 East 10th Street, Bloomington, IN 47405, USA
    Bipolar Disord 12:793-803. 2010
    ..We therefore evaluated the ASSR in bipolar disorder and examined its sensitivity to clinical symptoms, cognitive function, and pharmacological treatment...
  46. ncbi EEG synchrony during a perceptual-cognitive task: widespread phase synchrony at all frequencies
    Susan Pockett
    Department of Physics, University of Auckland, Private Bag 92019, Auckland, New Zealand
    Clin Neurophysiol 120:695-708. 2009
    ..1) To examine the validity of comparing the phase of broad-band signals. (2) To measure phase synchrony over the whole head, at a variety of frequencies...
  47. ncbi When frequencies never synchronize: the golden mean and the resting EEG
    Belinda Pletzer
    Department of Cell Biology, University of Salzburg, Salzburg, Austria
    Brain Res 1335:91-102. 2010
    ..These characteristics have already been discussed to lay the ground for a healthy interplay between various physiological processes (Buchmann, 2002)...
  48. ncbi Exploring intermediate phenotypes with EEG: working memory dysfunction in schizophrenia
    Corinna Haenschel
    Wales Institute of Cognitive Neuroscience, School of Psychology, Adeilad Brigantia, Bangor University, Gwynedd LL57 2AS, UK
    Behav Brain Res 216:481-95. 2011
    ..These links have already resulted in the development of new remediation strategies, which have some translational potential...
  49. ncbi Neural synchronization deficits to auditory stimulation in bipolar disorder
    BRIAN F O'DONNELL
    Department of Psychology, Indiana University, Bloomington, IN 47405, USA
    Neuroreport 15:1369-72. 2004
    ..Abnormal high frequency neural synchronization may contribute to cognitive deficits in bipolar disorder...
  50. pmc Dangerous phase
    Steven J Schiff
    Krasnow Institute, George Mason University, Fairfax, VA, USA
    Neuroinformatics 3:315-8. 2005
    ..The good news is that the fix to remove common reference artifacts is simple. The bad news is that the interpretation of reference- free synchronization results from brain signals requires considerable caution...
  51. pmc Reliability, synchrony and noise
    G Bard Ermentrout
    Department of Mathematics, University of Pittsburgh, Thackery Hall, Pittsburgh, PA 15260, USA
    Trends Neurosci 31:428-34. 2008
    ..These results raise fundamental questions about how noise can influence neural function and computation...
  52. ncbi Impaired extinction of fear and maintained amygdala-hippocampal theta synchrony in a mouse model of temporal lobe epilepsy
    Jörg Lesting
    Institute for Physiology I, Muenster, Germany
    Epilepsia 52:337-46. 2011
    ..Therefore, this project was set up to characterize the neurophysiologic basis of seizure-related fear and the contribution of the amygdala-hippocampus system...
  53. ncbi Multiple origins of the cortical γ rhythm
    Miles A Whittington
    Institute of Neuroscience, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom
    Dev Neurobiol 71:92-106. 2011
    ..Finally, we suggest that developmental disruption of the endophenotype for certain subsets of gamma-generating interneuron may underlie cognitive deficit in psychiatric illness...
  54. ncbi Reduction in subthalamic 8-35 Hz oscillatory activity correlates with clinical improvement in Parkinson's disease
    Andrea A Kuhn
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WCIN 3BG, UK
    Eur J Neurosci 23:1956-60. 2006
    ..Our results support a link between levodopa-induced improvements in bradykinesia and rigidity and reductions in population synchrony at frequencies < 35 Hz in the region of the STN in patients with PD...
  55. ncbi A role of beta oscillatory synchrony in biasing response competition?
    B C M van Wijk
    Research Institute MOVE, VU University Amsterdam, Amsterdam, The Netherlands
    Cereb Cortex 19:1294-302. 2009
    ....
  56. ncbi Beta electroencephalograph changes during passive movements: sensory afferences contribute to beta event-related desynchronization in humans
    M Alegre
    Neurophysiology Section, Department of Neurology, Clinica Universitaria de Navarra, Pio XII 36, 31008, Pamplona, Spain
    Neurosci Lett 331:29-32. 2002
    ..These findings suggest that afferent proprioceptive inputs may play a role in the final part of the beta ERD observed during voluntary movements...
  57. ncbi Visuomotor integration is associated with zero time-lag synchronization among cortical areas
    P R Roelfsema
    Max Planck Institute for Brain Research, Frankfurt, Germany
    Nature 385:157-61. 1997
    ..During reward and inter-trial episodes, zero-time-lag synchrony was lost and replaced by interactions exhibiting large and unsystematic time lags...
  58. ncbi Detecting alpha rhythm phase reset by phase sorting: caveats to consider
    Petra Ritter
    Bernstein Center for Computational Neuroscience Berlin, Germany
    Neuroimage 47:1-4. 2009
    ..We will discuss other criteria necessary for further confirmation of the phase reset theory...
  59. ncbi Inhibitory postsynaptic potentials carry synchronized frequency information in active cortical networks
    Andrea Hasenstaub
    Department of Neurobiology, Kavli Institute of Neuroscience, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Neuron 47:423-35. 2005
    ..Our results support the hypothesis that inhibitory networks are largely responsible for the dissemination of higher-frequency activity in cortex...
  60. ncbi Asymmetric spatiotemporal patterns of event-related desynchronization preceding voluntary sequential finger movements: a high-resolution EEG study
    Ou Bai
    Human Motor Control Section, Medical Neurological Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1428, USA
    Clin Neurophysiol 116:1213-21. 2005
    ..To study spatiotemporal patterns of event-related desynchronization (ERD) preceding voluntary sequential finger movements performed with dominant right hand and nondominant left hand...
  61. ncbi GLM-beamformer method demonstrates stationary field, alpha ERD and gamma ERS co-localisation with fMRI BOLD response in visual cortex
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, UK
    Neuroimage 26:302-8. 2005
    ....
  62. ncbi Evoked gamma band synchronization and the liability for schizophrenia
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, P O Box 21247, Baltimore, MD 21228, USA
    Schizophr Res 70:293-302. 2004
    ....
  63. pmc Impaired inhibitory control of cortical synchronization in fragile X syndrome
    Scott M Paluszkiewicz
    Children s National Medical Center, Washington, DC 20010, USA
    J Neurophysiol 106:2264-72. 2011
    ..Together, these findings reveal a functional defect in a single subtype of cortical interneuron in Fmr1 KO mice. This defect is linked to altered activity of the cortical network in line with the FXS phenotype...
  64. ncbi A short review of slow phase synchronization and memory: evidence for control processes in different memory systems?
    Wolfgang Klimesch
    Department of Physiological Psychology, University of Salzburg, Austria
    Brain Res 1235:31-44. 2008
    ..The hypothesis, suggested here is that theta and upper alpha reflect these processes which can be best studied when analyzing phase...
  65. ncbi MEG resting state functional connectivity in Parkinson's disease related dementia
    J L W Bosboom
    Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands
    J Neural Transm 116:193-202. 2009
    ..The observed changes in functional connectivity are reminiscent of changes in AD, and may reflect reduced cholinergic activity and/or loss of cortico-cortical anatomical connections in PDD...
  66. ncbi Disturbed functional connectivity in brain tumour patients: evaluation by graph analysis of synchronization matrices
    Fabrice Bartolomei
    Department of Clinical Neurophysiology, VU University Medical Center, Amsterdam, The Netherlands
    Clin Neurophysiol 117:2039-49. 2006
    ..The present work aims at evaluating the impact of brain tumours on spatial patterns of functional connectivity of the brain measured at rest by MEG...
  67. ncbi Gamma-range corticomuscular coherence during dynamic force output
    Wolfgang Omlor
    Neurological Clinic, Albert Ludwigs University, Breisacher Strasse 64, 79106 Freiburg, Germany
    Neuroimage 34:1191-8. 2007
    ....
  68. ncbi Cannabinoids reveal importance of spike timing coordination in hippocampal function
    David Robbe
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    Nat Neurosci 9:1526-33. 2006
    ..We hypothesize that reduced spike timing coordination and the associated impairment of physiological oscillations are responsible for cannabinoid-induced memory deficits...
  69. pmc Dynamic links between theta executive functions and alpha storage buffers in auditory and visual working memory
    Masahiro Kawasaki
    Rhythm based Brain Computation Unit, RIKEN BSI TOYOTA Collaboration Center, Wako Shi, Saitama, Japan
    Eur J Neurosci 31:1683-9. 2010
    ....
  70. ncbi Attention to a painful cutaneous laser stimulus modulates electrocorticographic event-related desynchronization in humans
    S Ohara
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD 21287 7247, USA
    Clin Neurophysiol 115:1641-52. 2004
    ..To test the hypothesis that attention to painful cutaneous laser stimuli enhances event-related desynchronization (ERD) in cortical regions receiving nociceptive input...
  71. ncbi The influence of ageing on complex brain networks: a graph theoretical analysis
    Sifis Micheloyannis
    Faculty of Medicine, L Widen Laboratory, University of Crete, Iraklion, Crete, Greece
    Hum Brain Mapp 30:200-8. 2009
    ....
  72. pmc 'Functional connectivity' is a sensitive predictor of epilepsy diagnosis after the first seizure
    Linda Douw
    Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands
    PLoS ONE 5:e10839. 2010
    ..Here we investigate whether using 'functional connectivity' can improve the diagnostic sensitivity of the first interictal EEG in the diagnosis of epilepsy...
  73. ncbi Neuronal desynchronization as a trigger for seizure generation
    Yue Li
    Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA
    IEEE Trans Neural Syst Rehabil Eng 16:62-73. 2008
    ..These results provide a possible pathway in which a decrease in synchronization could provide the trigger for inducing epileptiform activity...
  74. ncbi Abnormal oscillatory synchronisation in the motor system leads to impaired movement
    P Brown
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London WC1N 3BG, UK
    Curr Opin Neurobiol 17:656-64. 2007
    ..Here, pathologically synchronised discharges of pyramidal neurons are transmitted to the healthy spinal cord. The result is the synchronous discharge of motor units leading to rhythmic jerking...
  75. ncbi Cognitive network interactions and beta 2 coherence in processing non-target stimuli in visual oddball task
    M Kukleta
    Department of Physiology, Brno, Czech Republic
    Physiol Res 58:139-48. 2009
    ....
  76. ncbi Task-related changes in cortical synchronization are spatially coincident with the hemodynamic response
    Krish D Singh
    The Wellcome Trust Laboratory for MEG Studies, Neurosciences Research Institute, Aston University, Birmingham, United Kingdom
    Neuroimage 16:103-14. 2002
    ..The results show that frequency-specific, task-related changes in cortical synchronization, detected using MEG, match those areas of the brain showing an evoked cortical hemodynamic response with ..
  77. ncbi EEG phase synchronization in patients with paranoid schizophrenia
    Petr Bob
    First Faculty of Medicine, Center for Neuropsychiatric Research of Traumatic Stress, Charles University, Prague, Czech Republic
    Neurosci Lett 447:73-7. 2008
    ..35 Hz. This finding suggests that higher and lower frequencies may play a specific role in binding and connectivity and may be related to decreased or increased synchrony with specific manifestation in cognitive deficits of schizophrenia...
  78. ncbi Tuning neocortical pyramidal neurons between integrators and coincidence detectors
    Michael Rudolph
    Unité de Neuroscience Intégratives et Computationnelles, CNRS, UPR 2191, Bat 32 33, Avenue de la Terrasse, 91198 Gif sur Yvette, France
    J Comput Neurosci 14:239-51. 2003
    ..Thus, background activity not only sharpens cortical responses but it can also be used to tune an entire network between integration and coincidence detection modes...
  79. ncbi Attenuation of long-range temporal correlations in the amplitude dynamics of alpha and beta neuronal oscillations in patients with schizophrenia
    Vadim V Nikulin
    Neurophysics Group, Department of Neurology, Charite Universitatsmedizin, D 12200 Berlin, Germany
    Neuroimage 61:162-9. 2012
    ..Attenuated LRTC might allow for more random associations between neuronal activations, which in turn might relate to the occurrence of thought disorders in schizophrenia...
  80. ncbi Post-movement beta synchronization in subjects presenting with sensory deafferentation
    N Reyns
    Department of Functional Neurosurgery, EA 2683, University Hospital, Lille, France
    Clin Neurophysiol 119:1335-45. 2008
    ....
  81. pmc Brains swinging in concert: cortical phase synchronization while playing guitar
    Ulman Lindenberger
    Center for Lifespan Psychology, Max Planck Institute for Human Development, Lentzeallee 94, 14195 Berlin, Germany
    BMC Neurosci 10:22. 2009
    ....
  82. pmc Sleep homeostasis and cortical synchronization: II. A local field potential study of sleep slow waves in the rat
    Vladyslav V Vyazovskiy
    Department of Psychiatry, University of Wisconsin, Madison, WI 53719, USA
    Sleep 30:1631-42. 2007
    ..Here we tested the model predictions by obtaining LFP recordings from the rat cerebral cortex and comparing conditions of high homeostatic sleep pressure (early sleep) and low homeostatic sleep pressure (late sleep)...
  83. ncbi Frequency flows and the time-frequency dynamics of multivariate phase synchronization in brain signals
    David Rudrauf
    LENA, MEG EEG Center Pitié Salpêtrière, CNRS UPR 640, Universite Pierre et Marie Curie, 47 bd de l Hopital, 75651 Paris Cedex 13, France
    Neuroimage 31:209-27. 2006
    ....
  84. ncbi Comparison of Hilbert transform and wavelet methods for the analysis of neuronal synchrony
    M Le Van Quyen
    laboratoire de neurosciences cognitives et imagerie cérébrale LENA, Hopital de la Salpetriere, CNRS UPR 640, 47 bd de l Hopital, 75651 Cedex 13, Paris, France
    J Neurosci Methods 111:83-98. 2001
    ..This offers a common language and framework that can be used for future research in the area of synchronization...
  85. ncbi Synchronized oscillations at alpha and theta frequencies in the lateral geniculate nucleus
    Stuart W Hughes
    School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3US, United Kingdom
    Neuron 42:253-68. 2004
    ..We propose that mGluR1a-induced oscillations are a potential mechanism whereby the thalamus promotes EEG alpha and theta rhythms in the intact brain...
  86. ncbi Oscillatory nature of human basal ganglia activity: relationship to the pathophysiology of Parkinson's disease
    Peter Brown
    Sobell Department of Neurophysiology and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 18:357-63. 2003
    ..The lower frequency oscillations facilitate slow idling rhythms in the motor areas of the cortex, whereas synchronisation at high frequency restores dynamic task-related cortical ensemble activity in the gamma band...
  87. ncbi Beta 2-band synchronization during a visual oddball task
    M Kukleta
    Department of Physiology, Masaryk University, Komenskeho 2, 662 43 Brno, Czech Republic
    Physiol Res 58:725-32. 2009
    ....
  88. ncbi Graph properties of synchronized cortical networks during visual working memory maintenance
    Satu Palva
    Neuroscience Center, University of Helsinki, Finland
    Neuroimage 49:3257-68. 2010
    ..These data further show that synchronized dynamic networks underlying a specific cognitive state can exhibit distinct frequency-dependent network structures that could support distinct functional roles...
  89. ncbi Reduced movement-related β desynchronisation in juvenile myoclonic epilepsy: a MEG study of task specific cortical modulation
    Khalid Hamandi
    The Epilepsy Unit, University Hospital of Wales, Cardiff CF14 4XW, UK
    Clin Neurophysiol 122:2128-38. 2011
    ..We investigated differences in task induced responses in occipital and sensorimotor cortex between patients with juvenile myclonic epilepsy (JME) and healthy controls ...
  90. ncbi Disturbed post-movement beta synchronization in Wilson's disease with neurological manifestation
    Gertrúd Tamás
    Department of Neurology, Semmelweis University, Balassa u 6, 1083 Budapest, Hungary
    Neurosci Lett 494:240-4. 2011
    ..Since decreased power of PMBS was observed in Parkinson's disease and increased latency in essential tremor, the combined change of PMBS can indicate pathology of different neural circuits and may help the diagnosis in challenging cases...
  91. ncbi Synchronization of neuronal responses in primary visual cortex of monkeys viewing natural images
    Pedro Maldonado
    Centro de Neurociencias Integradas and Programa de Fisiología y Biofísica, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    J Neurophysiol 100:1523-32. 2008
    ..The short latency of the stimulation-related synchronization phenomena suggests a fast-acting mechanism for the coordination of spike timing that may contribute to the basic operations of scene segmentation...
  92. ncbi The neuronal basis of attention: rate versus synchronization modulation
    Andres Buehlmann
    Computational Neuroscience, Universitat Pompeu Fabra, 08003 Barcelona, Spain
    J Neurosci 28:7679-86. 2008
    ..However, we show that there is an advantage in the processing of information if rate modulation is accompanied by gamma modulation, namely that reaction times are shorter, implying behavioral relevance for gamma synchronization...
  93. ncbi Functional neural networks underlying semantic encoding of associative memories
    M Crespo-Garcia
    Laboratory of Functional Neuroscience, Network for Biomedical Research on Neurodegenerative Diseases CIBERNED, University Pablo de Olavide, Seville, Spain
    Neuroimage 50:1258-70. 2010
    ....
  94. ncbi Electroencephalogram functional connectivity between rat hippocampus and cortex after pilocarpine treatment
    S Tejada
    Department of Biologia Fonamental i Ciències de la Salut, University of the Balearic Islands, IUNICS, Palma de Mallorca, Spain
    Neuroscience 165:621-31. 2010
    ..In conclusion, the present EEG study could suggest an effect of the muscarinic cholinergic agonist pilocarpine on the hippocampal-cortical functional connectivity...
  95. ncbi Evaluation of different measures of functional connectivity using a neural mass model
    Olivier David
    Functional Imaging Laboratory, Wellcome Department of Imaging Neuroscience, London WC1N 3BG, UK
    Neuroimage 21:659-73. 2004
    ..We illustrate this using a single-subject MEG study of binocular rivalry and highlight the greater recovery of statistical dependencies among cortical areas in the beta band when mutual information is used...
  96. ncbi Synchronization of neural oscillations as a possible mechanism underlying episodic memory: a study of theta rhythm in the hippocampus
    Yoko Yamaguchi
    Laboratory for Dynamics of Emergent Intelligence, RIKEN Brain Science Institute, Wako Shi, Saitama 351 0198, Japan
    J Integr Neurosci 3:143-57. 2004
    ..Further comparison with electrophysiological data from both rodents and primates suggests a possible role of theta oscillations in memory encoding and online processing of episodic events...
  97. ncbi Heritability of "small-world" networks in the brain: a graph theoretical analysis of resting-state EEG functional connectivity
    Dirk J A Smit
    Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands
    Hum Brain Mapp 29:1368-78. 2008
    ..It is asserted that C, L, and a small-world organization are viable markers of genetic differences in brain organization...
  98. pmc Sleep homeostasis and cortical synchronization: I. Modeling the effects of synaptic strength on sleep slow waves
    Steve K Esser
    Department of Psychiatry, University of Wisconsin, Madison, WI 53719, USA
    Sleep 30:1617-30. 2007
    ..Based on a recent hypothesis, we sought to determine whether a decrease in cortical synaptic strength can account for changes in sleep SWA...
  99. ncbi Epileptic seizures are preceded by a decrease in synchronization
    Florian Mormann
    Department of Epileptology, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Epilepsy Res 53:173-85. 2003
    ....
  100. ncbi Event-related beta synchronization after wrist, finger and thumb movement
    G Pfurtscheller
    Department of Medical Informatics, Institute for Biomedical Engineering, University of Technology, Graz, Austria
    Electroencephalogr Clin Neurophysiol 109:154-60. 1998
    ..Summarizing, pre-movement desynchronization seems relatively independent of the forthcoming type of movement, whereas the post-movement beta synchronization might depend on the activated muscle mass...
  101. ncbi P300 and alpha event-related desynchronization (ERD)
    J Yordanova
    Institute of Physiology, Bulgarian Academy of Sciences, Sofia
    Psychophysiology 38:143-52. 2001
    ..These findings indicate that P300 and ERD are related such that slow and fast alpha ERDs are specifically guided or modified by the internal event(s) indexed by P300...

Research Grants62

  1. Neural synchronydysfunction of gamma oscillations in autism
    Donald C Rojas; Fiscal Year: 2013
    ..Using a whole-head MEG system, we will assess patterns of auditory cortical synchronization with high precision in both time and frequency...
  2. ADVANCED TECHNIQUES FOR ANALYZING CORTICAL DYNAMICS
    Steven Bressler; Fiscal Year: 1999
    ..small portion of this NIMH data set, reported in Nature in 1993, revealed shifting patterns of multi-site cortical synchronization during visuomotor processing, and implicated synchronization in the formation of functional relations ..
  3. PERCEPTION AND PRODUCTION OF EXPRESSIVE MICROSTRUCTURE
    Bruno Repp; Fiscal Year: 2002
    ..This research is expected to provide new insights into the largely subconscious psychological processes underlying the flexible control of timing in both musical and nonmusical contexts. ..
  4. Neural Temporal Coding Mechanisms of Tactile Attention
    Ernst Niebur; Fiscal Year: 2007
    ..Aim 3 is to study the mechanisms underlying the generation of synchrony. One hypothesis that will be tested is phase locking of action potentials to a periodic function (oscillations). ..
  5. The Effects of Cannabis Use/Abuse on In Vivo Dopamine Function
    WILLIAM FRANKLE; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  6. Circuit Mechanisms of Cortical Synchronizations
    Brendon Watson; Fiscal Year: 2008
    ..abstract_text> ..
  7. Network Models of Seizure Dynamics and Evolution
    Pawel Kudela; Fiscal Year: 2008
    ..This can facilitate development of technology for controlling or reducing the frequency of seizures and lead to possibilities for developing new treatment options for patients with epilepsy. [unreadable] [unreadable] [unreadable]..
  8. Neurophysiological Basis of fMRI
    Charles Schroeder; Fiscal Year: 2007
    ..This will help to bridge-the-gap between a vast single unit literature in monkeys, and a developing understanding of somatosensory structure and function in humans. ..
  9. Cortical Plasticity and Processing of Speech Sounds
    Michael Kilgard; Fiscal Year: 2006
    ..Insights derived from these studies will influence the use and development of behavioral and sensory rehabilitation of language impairments. ..
  10. Functional Organization of Somatosensory Cortex
    KEVIN ALLOWAY; Fiscal Year: 2007
    ..To address this issue, conditional cross-correlation analysis will be used to quantify the impact of synchronized activity in SI on the probability of neuronal responsiveness in corresponding parts of the MI whisker representation. ..
  11. Connexins in Ischemia-Induced Neuronal Death
    Michael Bennett; Fiscal Year: 2007
    ..Moreover, this study has important implications for research on other neurodegenerative disorders including focal ischemia, epilepsy, AIDS encephalopathy, and Alzheimer's disease. ..
  12. The Effect of Cannabis Use on Human Cerebellar Function
    PATRICK SKOSNIK; Fiscal Year: 2008
    ..Project Narrative [unreadable] [unreadable] [unreadable]..
  13. Course Development in the Neurobiology of Disease
    Jeffrey Noebels; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  14. Neurobehavioral correlates of bipolar disorder
    BRIAN O DONNELL; Fiscal Year: 2006
    ..abstract_text> ..
  15. Non-invasive Fast Optical Imaging of Visual and Motor Processing
    Andrei Medvedev; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  16. Somatosensory Cortical Influences on Subcortical Processing
    KEVIN ALLOWAY; Fiscal Year: 2007
    ..Aim 4. Support or refute the hypothesis that stimulus-induced neuronal activity in SI barrel cortex and the pons are more strongly correlated than stimulus-induced activity in SI cortex and the neostriatum. ..
  17. Hypocretin and Drug Addiction
    Luis de Lecea; Fiscal Year: 2010
    ..This demonstration may lead to future treatments to prevent relapse. ..
  18. Somatosensory Cortical Influences on Subcortical Processing
    KEVIN DOUGLAS ALLOWAY; Fiscal Year: 2010
    ....
  19. Conceptual Processing in Alzheimer's Disease
    Murray Grossman; Fiscal Year: 2010
    ..This work will help facilitate communication in the day-to-day care of patients with AD, and advance our understanding of a fundamental aspect of cognition. ..
  20. D-Cycloserine Enhancement of Exposure in Social Phobia
    Stefan G Hofmann; Fiscal Year: 2010
    ..This study addresses an important public health issue by assessing an intervention that may lead to a more efficient and effective application of empirically based psychosocial interventions for the treatment of SAD. ..
  21. Somato-Auditory Convergence: Supratemporal Plane
    Charles Schroeder; Fiscal Year: 2009
    ..Because of our unique combination of methods we can bridge the gap between incisive findings from in-vitro cellular-level experiments and effects noted by electromagnetic and hemodynamic imaging studies in humans. ..
  22. Parallel Sequence Profiling of Ion Channels in Epilepsy
    Jeffrey Noebels; Fiscal Year: 2008
    ..abstract_text> ..
  23. BDNF AND HIPPOCAMPAL HYPEREXCITABILITY
    Helen Scharfman; Fiscal Year: 2008
    ..We will now address the hypothesis that BDNF induction by estrogen increases pyramidal cell activation, and the induction of VEGF by estrogen ensures that seizures are prevented. ..
  24. Visual Processing in Schizophrenia and SPD
    BRIAN O DONNELL; Fiscal Year: 2009
    ..These findings may identify neurobehavioral deficits common to SZ and SPD, as well as features which differentiate these disorders. ..
  25. ANESTHETIC EFFECTS ON SENSORIMOTOR INTEGRATION
    JOSEPH ANTOGNINI; Fiscal Year: 2009
    ..Understanding how and where anesthetics act will eventually lead to the development of better and safer anesthetics, thereby decreasing peri-operative morbidity and mortality and improving public health. ..
  26. Modulation of auditory processing by behavioral state
    Marc Schmidt; Fiscal Year: 2009
    ..We hypothesize that the behavioral context with which the heard song is produced as well as the identity of the singer will significantly influence auditory responses. ..
  27. Identifying molecular path of behavioural phenotype in schizophrenia
    L Hong; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  28. An EEG Study of Neural Dynamics in Schizophrenia
    Kevin Spencer; Fiscal Year: 2006
    ..This project seeks to further this goal by studying how brainwave synchronization is related to perception and thinking in people who are healthy, and in people who have schizophrenia. [unreadable] [unreadable] [unreadable]..
  29. NEUROPEPTIDE CORTISTATIN AND SLEEP
    Luis de Lecea; Fiscal Year: 2006
    ..These features and others make cortistatin a sleep factor that may have a major role in cortical synchronization and the maintenance of slow wave sleep...
  30. BRAIN AND SPINAL CORD CONTRIBUTIONS TO ANESTHETIC ACTION
    JOSEPH ANTOGNINI; Fiscal Year: 2005
    ..This information will aid the development of newer and safer anesthetics, as well as lead to clinically useful means of modulating the neurotransmitter systems that are themselves modulated by anesthetics. ..
  31. Electrophysiology and Neurocognition in Schizophrenia
    Peter Bachman; Fiscal Year: 2004
    ..abstract_text> ..
  32. Liability Markers for Deficit Schizophrenia?
    L Hong; Fiscal Year: 2004
    ..We plan to use the preliminary data collected from this grant support to guide our full-scale search for phenotypic markers specifically associated with the liability for deficit schizophrenia and subsequent molecular genetic studies. ..
  33. TREATMENT OF SOCIAL PHOBIA--MEDIATORS AND MODERATORS
    Stefan Hofmann; Fiscal Year: 2002
    ..The main hypothesis is that perceived emotional control will mediate treatment outcome and generality of effectiveness independent of the specific treatment condition. ..
  34. Fine-grained analysis of vocal learning
    TODD TROYER; Fiscal Year: 2003
    ..By clarifying the principles governing vocal learning in songbirds, these models will yield insight into fundamental questions related to motor learning in humans. ..
  35. THALAMIC NEURON DYNAMICS AND ABSENCE EPILEPSY
    WILLIAM LYTTON; Fiscal Year: 2002
    ..Finally, we will assess the in vitro responses of interneurons and thalamocortical cells to protocols that mimic established models of absence epilepsy. ..
  36. TMS Intervention Development for Auditory Hallucinations
    Ralph Hoffman; Fiscal Year: 2003
    ..The results of these studies will be used to design an intervention algorithm for a full-scale trial of rTMS in a larger group of schizophrenic patients with medication-resistant AHs. ..
  37. DEVELOPMENT OF THE CORTICOTHALAMIC SYSTEM
    Edward Jones; Fiscal Year: 2003
    ..Defective maturation may be a concomitant of or a basis for certain forms of seizures in young individuals. ..
  38. MARIJUANA CNS EFFECTS IN LOW- AND HIGH-RISK ADULTS
    John Polich; Fiscal Year: 2002
    ..The most sensitive and effective paradigms will provide reliable neuroelectric signatures that reflect marihuana's cognitive effects. ..
  39. HILAR NEURONS IN HIPPOCAMPAL NETWORK FUNCTION
    Helen Scharfman; Fiscal Year: 2002
    ..The results will provide insight into cognitive function that should ultimately help in the understanding and treatment of learning disorders and mental illness. ..
  40. CORTICAL PLASTICITY AND PROCESSING OF COMPLEX STIMULI
    Michael Kilgard; Fiscal Year: 2002
    ..Our continuing studies will examine several other acoustic stimuli to determine precisely what stimulus features are required to generate each element of representational plasticity observed in our preliminary results. ..
  41. Cognitive Impairments in Parkinson's Disease and Aging
    Murray Grossman; Fiscal Year: 2006
    ..Our data support a componential neurocognitive architecture consisting of dynamically interactive networks modified to process sentences depending on available resources and relative demand. ..
  42. FAST ELECTRICAL OSCILLATIONS IN SOMATOSENSORY CORTEX
    DANIEL BARTH; Fiscal Year: 2006
    ..abstract_text> ..
  43. STRIATAL ORGANIZATION AND DOPAMINE RECEPTOR LOCALIZATION
    John Marshall; Fiscal Year: 2006
    ..The significance of this work derives both from its relevance to basal ganglia disorders such as Parkinson's disease and also because of its potential to elucidate the significance of the pallidostriatal circuitry. ..
  44. The Role of the Amygdala in Anesthetic-Induced Amnesia
    MICHAEL ALKIRE; Fiscal Year: 2006
    ..abstract_text> ..
  45. A Prospective Longitudinal Study of PANDAS
    James Leckman; Fiscal Year: 2005
    ..These insights may be relevant to our understanding of other diseases including AIDS. ..
  46. The hypocretins and alcohol dependence
    Luis de Lecea; Fiscal Year: 2003
    ..The development of these mouse models will generate invaluable tools to assess the role of the hypocretins on drug abuse, and may help to design better treatments for sleep disorders associated with alcoholism. ..
  47. AUTOMATIC ELICITATION OF COGNITIVE ERP COMPONENTS
    Judith Ford; Fiscal Year: 2001
    ..By combining ERP and fMRI methods we will characterize the spatio-tumoral dynamics of the neuroanatomic circuit(s) involved in normal and abnormal response monitoring. ..
  48. Rhythms of the Nervous System
    Nancy Kopell; Fiscal Year: 2005
    ..We will also study, both experimentally and via modeling, separated networks that produce a coherent gamma rhythm, and networks distributed over space. ..
  49. Infant Temperament and Cognitive Development
    MARTHA BELL; Fiscal Year: 2004
    ..Likewise, they have the potential to generate hypotheses about foundations for the development of extremes in self-regulation (i.e., attention deficit disorder, depression) and associated complexities in cognition. ..
  50. Pathway(s) From Genes to Functional Deficits of Schizophrenia Patients
    Gregory A Light; Fiscal Year: 2010
    ....
  51. Sensory Processing Deficits in Cannabis Use
    PATRICK SKOSNIK; Fiscal Year: 2006
    ..Taken together, this data may serve to elucidate whether the known cognitive dysfunction observed in cannabis use is in part related to disturbances in early sensory information processing and/or neural synchronization. ..
  52. INTEGRATIVE APPROACH TO CORTICAL COGNITIVE NETWORKS
    JOAQUIN FUSTER; Fiscal Year: 2009
    ..These correlations are expected to provide crucial information on the neuronal basis of functional imaging signals, such as those obtained by BOLD fMRI, in human cognition. ..
  53. Reverse Engineering Cortical Circuitry
    WILLIAM LYTTON; Fiscal Year: 2007
    ..This will set the stage for use of the subiculum slice and subiculum computer model as an epilepsy model. ..
  54. COMPUTATIONAL ASPECTS OF PRIMATE MEMORY
    JOAQUIN FUSTER; Fiscal Year: 2004
    ..A better understanding of the neural dynamics of memory may help us better understand the pathogenesis of memory disorders in the mentally ill and thus lead to better treatments. ..
  55. The Neuroanatomy of Antipsychotic Drug Action
    WILLIAM FRANKLE; Fiscal Year: 2008
    ..abstract_text> ..
  56. Brain Lateralization in Adolescent Psychosis
    Donald Rojas; Fiscal Year: 2005
    ....
  57. Neuroelectric Assessment of Ecstasy Use in Young Adults
    John Polich; Fiscal Year: 2008
    ..Equal numbers of female and male subjects will be assessed in all phases. The proposed methods will characterize CNS differences from MDMA use to provide assessment of drug effects on cognition. ..
  58. Alcohol and Tobacco CNS Effects in Binge Drinkers
    JOHN M POLICH; Fiscal Year: 2010
    ....
  59. ACTIVITY-DEPENDENT PLASTICITY IN SENSORY CORTEX
    Edward Jones; Fiscal Year: 2004
    ....
  60. Neuroelectric Assessment of MDMA (Ecstasy) Use in Adults
    John Polich; Fiscal Year: 2003
    ..These results will provide fundamental data on how MDMA use may alter CNS function. ..
  61. Mechanisms for Odor Coding in the Olfactory System
    Maksim Bazhenov; Fiscal Year: 2008
    ..Since neuronal oscillations and synchrony are observed in other sensory systems, the conclusions of this study might also provide insights into information processing in other brain areas. [unreadable] [unreadable] [unreadable]..