electrocardiography

Summary

Summary: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.

Top Publications

  1. ncbi The electrocardiogram predicts one-year outcome of patients with unstable angina and non-Q wave myocardial infarction: results of the TIMI III Registry ECG Ancillary Study. Thrombolysis in Myocardial Ischemia
    C P Cannon
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 30:133-40. 1997
  2. ncbi Heart rate variability: origins, methods, and interpretive caveats
    G G Berntson
    Department of Psychology, Ohio State University, Columbus 43210, USA
    Psychophysiology 34:623-48. 1997
  3. ncbi Universal definition of myocardial infarction
    Kristian Thygesen
    Department of Medicine and Cardiology, Aarhus University Hospital, Tage Hansens, Aarhus C, Denmark
    Eur Heart J 28:2525-38. 2007
  4. ncbi A model for human ventricular tissue
    K H W J ten Tusscher
    Department of Theoretical Biology, Utrecht University, 3584 CH Utrecht, The Netherlands
    Am J Physiol Heart Circ Physiol 286:H1573-89. 2004
  5. ncbi Universal definition of myocardial infarction
    Kristian Thygesen
    Department of Medicine and Cardiology, Aarhus University Hospital, Tage Hansens, Gade 2, DK 8000 Aarhus C, Denmark
    J Am Coll Cardiol 50:2173-95. 2007
  6. ncbi Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
    W S Redfern
    Safety Assessment UK, AstraZeneca R and D Alderley Park, Macclesfield, Cheshire, UK
    Cardiovasc Res 58:32-45. 2003
  7. ncbi ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999
    Elliott M Antman
    Circulation 110:588-636. 2004
  8. ncbi Epidermal electronics
    Dae Hyeong Kim
    Department of Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Science 333:838-43. 2011
  9. pmc Genome-wide association study of PR interval
    Arne Pfeufer
    Institute of Human Genetics, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Germany
    Nat Genet 42:153-9. 2010
  10. ncbi Prevalence of long-QT syndrome gene variants in sudden infant death syndrome
    Marianne Arnestad
    Institute of Forensic Medicine, University of Oslo, Oslo, Norway
    Circulation 115:361-7. 2007

Detail Information

Publications317 found, 100 shown here

  1. ncbi The electrocardiogram predicts one-year outcome of patients with unstable angina and non-Q wave myocardial infarction: results of the TIMI III Registry ECG Ancillary Study. Thrombolysis in Myocardial Ischemia
    C P Cannon
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 30:133-40. 1997
    ..We sought to determine the prognostic value of the admission electrocardiogram (ECG) in patients with unstable angina and non-Q wave myocardial infarction (MI)...
  2. ncbi Heart rate variability: origins, methods, and interpretive caveats
    G G Berntson
    Department of Psychology, Ohio State University, Columbus 43210, USA
    Psychophysiology 34:623-48. 1997
    ..Summary guidelines for research in this area are outlined, and suggestions and prospects for future developments are considered...
  3. ncbi Universal definition of myocardial infarction
    Kristian Thygesen
    Department of Medicine and Cardiology, Aarhus University Hospital, Tage Hansens, Aarhus C, Denmark
    Eur Heart J 28:2525-38. 2007
  4. ncbi A model for human ventricular tissue
    K H W J ten Tusscher
    Department of Theoretical Biology, Utrecht University, 3584 CH Utrecht, The Netherlands
    Am J Physiol Heart Circ Physiol 286:H1573-89. 2004
    ..We conclude that the proposed model reproduces a variety of electrophysiological behaviors and provides a basis for studies of reentrant arrhythmias in human ventricular tissue...
  5. ncbi Universal definition of myocardial infarction
    Kristian Thygesen
    Department of Medicine and Cardiology, Aarhus University Hospital, Tage Hansens, Gade 2, DK 8000 Aarhus C, Denmark
    J Am Coll Cardiol 50:2173-95. 2007
  6. ncbi Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
    W S Redfern
    Safety Assessment UK, AstraZeneca R and D Alderley Park, Macclesfield, Cheshire, UK
    Cardiovasc Res 58:32-45. 2003
    ..To attempt to determine the relative value of preclinical cardiac electrophysiology data (in vitro and in vivo) for predicting risk of torsade de pointes (TdP) in clinical use...
  7. ncbi ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999
    Elliott M Antman
    Circulation 110:588-636. 2004
  8. ncbi Epidermal electronics
    Dae Hyeong Kim
    Department of Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Science 333:838-43. 2011
    ..We used this type of technology to measure electrical activity produced by the heart, brain, and skeletal muscles and show that the resulting data contain sufficient information for an unusual type of computer game controller...
  9. pmc Genome-wide association study of PR interval
    Arne Pfeufer
    Institute of Human Genetics, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Germany
    Nat Genet 42:153-9. 2010
    ..0056). This suggests a role for common variation in ion channel and developmental genes in atrial and atrioventricular conduction as well as in susceptibility to atrial fibrillation...
  10. ncbi Prevalence of long-QT syndrome gene variants in sudden infant death syndrome
    Marianne Arnestad
    Institute of Forensic Medicine, University of Oslo, Oslo, Norway
    Circulation 115:361-7. 2007
    ..Given the importance and potential implications of these observations, we performed a study to more accurately quantify the contribution to SIDS of LQTS gene mutations and rare variants...
  11. doi Dilated cardiomyopathy
    John Lynn Jefferies
    Pediatric Cardiology, Texas Children s Hospital, Baylor College of Medicine, Houston, TX, USA
    Lancet 375:752-62. 2010
    ..Arrhythmia therapy and prevention of sudden death continue to be mainstays of treatment. Despite progress over the past 10 years, outcomes need to be improved...
  12. doi Estimated radiation dose associated with cardiac CT angiography
    Jorg Hausleiter
    Department of Cardiology, Deutsches Herzzentrum Munchen, Klinik an der Technischen Universität München, Lazarettstrasse 36, 80636 München, Germany
    JAMA 301:500-7. 2009
    ..However, the potential risks due to exposure to ionizing radiation associated with CCTA have raised concerns...
  13. doi 2007 focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    Elliott M Antman
    J Am Coll Cardiol 51:210-47. 2008
  14. pmc Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A)
    D Woodrow Benson
    Department of Pediatrics, Cincinnati Children s Hospital, Ohio, USA
    J Clin Invest 112:1019-28. 2003
    ..Our findings reveal a molecular basis for some forms of congenital SSS and define a recessive disorder of a human heart voltage-gated sodium channel...
  15. pmc A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project
    Fabio Marroni
    Institute of Genetic Medicine, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Munich, Germany
    Circ Cardiovasc Genet 2:322-8. 2009
    ..We set out to identify common genetic determinants of the length of the RR and QT intervals in 2325 individuals from isolated European populations...
  16. doi SCN5A mutations and the role of genetic background in the pathophysiology of Brugada syndrome
    Vincent Probst
    INSERM, UMR915, Nantes, France
    Circ Cardiovasc Genet 2:552-7. 2009
    ..However, in familial studies, the relationship between SCN5A mutations and BrS remains poorly understood. The aim of this study was to investigate the association of SCN5A mutations and BrS in a group of large genotyped families...
  17. ncbi Low-dose, 128-slice, dual-source CT coronary angiography: accuracy and radiation dose of the high-pitch and the step-and-shoot mode
    Hatem Alkadhi
    University Hospital Zurich, Institute of Diagnostic Radiology, Raemistrasse 100, Zurich, Switzerland
    Heart 96:933-8. 2010
    ..To compare the diagnostic accuracy and radiation doses of two low-dose protocols for coronary artery imaging with second-generation, dual-source CT in comparison with catheter angiography (CA)...
  18. ncbi Risk of arrhythmias in myotonic dystrophy: trial design of the RAMYD study
    Antonio Dello Russo
    Institute of Cardiology, Department of Cardiovascular Medicine, Catholic University, L go A Gemelli 8, 00168 Rome, Italy
    J Cardiovasc Med (Hagerstown) 10:51-8. 2009
    ....
  19. ncbi An advanced detrending method with application to HRV analysis
    Mika P Tarvainen
    University of Kuopio, Department of Applied Physics, Finland
    IEEE Trans Biomed Eng 49:172-5. 2002
    ..The method is based on smoothness priors approach and operates like a time-varying finite-impulse response high-pass filter. The effect of the detrending on time- and frequency-domain analysis of HRV is studied...
  20. doi Arrhythmogenic right ventricular cardiomyopathy
    Cristina Basso
    University of Padua Medical School, Padua, Italy
    Lancet 373:1289-300. 2009
    ..Cascade genetic screening of family members of gene-positive probands allows the identification of asymptomatic carriers who would require lifelong follow-up due to the age-related penetrance...
  21. ncbi Genetic variation in SCN10A influences cardiac conduction
    John C Chambers
    Department of Epidemiology and Public Health, Imperial College London, UK
    Nat Genet 42:149-52. 2010
    ..05) and a lower risk of ventricular fibrillation (P = 0.01). Our findings provide new insight into the pathogenesis of cardiac conduction, heart block and ventricular fibrillation...
  22. pmc Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction
    Nona Sotoodehnia
    Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA
    Nat Genet 42:1068-76. 2010
    ..These findings extend our current knowledge of ventricular depolarization and conduction...
  23. ncbi Outcome parameters for trials in atrial fibrillation: executive summary
    Paulus Kirchhof
    Department of Cardiology and Angiology, University Hospital Munster, Albert Schweitzer Strasse 33, D 48149 Munster, Germany
    Eur Heart J 28:2803-17. 2007
    ..In addition to a careful selection of a relevant primary outcome parameter, coverage of outcomes in all major domains of AF-related morbidity and mortality is desirable for any clinical trial in AF...
  24. ncbi Feasibility of low-dose coronary CT angiography: first experience with prospective ECG-gating
    Lars Husmann
    Department of Medical Radiology and Cardiovascular Center, University Hospital Zurich, Raemistr 100, CH 8091 Zurich, Switzerland
    Eur Heart J 29:191-7. 2008
    ..To determine the feasibility of prospective electrocardiogram (ECG)-gating to achieve low-dose computed tomography coronary angiography (CTCA)...
  25. pmc Prevalence and prognosis of unrecognized myocardial infarction determined by cardiac magnetic resonance in older adults
    Erik B Schelbert
    National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    JAMA 308:890-6. 2012
    Unrecognized myocardial infarction (MI) is prognostically important. Electrocardiography (ECG) has limited sensitivity for detecting unrecognized MI (UMI).
  26. ncbi Impaired impulse propagation in Scn5a-knockout mice: combined contribution of excitability, connexin expression, and tissue architecture in relation to aging
    Toon A B van Veen
    Heart Lung Center, Department of Medical Physiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Circulation 112:1927-35. 2005
    ..The SCN5A sodium channel is a major determinant for cardiac impulse propagation. We used epicardial mapping of the atria, ventricles, and septae to investigate conduction velocity (CV) in Scn5a heterozygous young and old mice...
  27. ncbi A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrate
    Koonlawee Nademanee
    Pacific Rim Electrophysiology Research Institute, Inglewood, California 90301, USA
    J Am Coll Cardiol 43:2044-53. 2004
    ..We sought to test the hypothesis that complex fractionated electrograms (CFAEs) recorded during atrial fibrillation (AF) could be used as target sites for catheter ablation of AF...
  28. ncbi A cardiac sodium channel mutation cosegregates with a rare connexin40 genotype in familial atrial standstill
    W Antoinette Groenewegen
    Department of Medical Physiology, University Medical Center, Utrecht, The Netherlands
    Circ Res 92:14-22. 2003
    ..We propose that, although the functional effect of each genetic change is relatively benign, the combined effect of genetic changes eventually progresses to total AS...
  29. ncbi Increased temporal dispersion of myocardial repolarization in myotonic dystrophy type 1: beyond the cardiac conduction system
    Damiano Magrì
    Cardiology Department, S Andrea Hospital, Sapienza University of Rome, Rome, Italy
    Int J Cardiol 156:259-64. 2012
    ..We also investigated the possible differences within DM1 patients by subdividing them according either to the presence of first degree atrioventricular block (1st AVB) or to the cytosine-thymine-guanine (CTG) repeat expansion size...
  30. ncbi Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial
    Michael Bohm
    Universitatsklinikum des Saarlandes, Klinik fur Innere Medizin III, Homburg Saar, Germany
    Lancet 376:886-94. 2010
    ..We aimed to test our hypothesis by investigating the association between heart rate and events in this patient population...
  31. ncbi Wavelet transforms and the ECG: a review
    Paul S Addison
    CardioDigital Ltd, Elvingston Science Centre, East Lothian, UK
    Physiol Meas 26:R155-99. 2005
    ..In this review, the emerging role of the wavelet transform in the interrogation of the ECG is discussed in detail, where both the continuous and the discrete transform are considered in turn...
  32. pmc Autonomic nervous system dysfunction and inflammation contribute to the increased cardiovascular mortality risk associated with depression
    Willem J Kop
    Department of Medicine, Division of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA
    Psychosom Med 72:626-35. 2010
    ..To investigate prospectively whether autonomic nervous system (ANS) dysfunction and inflammation play a role in the increased cardiovascular disease (CVD)-related mortality risk associated with depression...
  33. pmc ECG quantification of myocardial scar in cardiomyopathy patients with or without conduction defects: correlation with cardiac magnetic resonance and arrhythmogenesis
    David G Strauss
    Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Circ Arrhythm Electrophysiol 1:327-36. 2008
    ....
  34. ncbi STEMI and NSTEMI: are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry)
    Gilles Montalescot
    Institut de Cardiologie and INSERM U856, Pitie Salpetriere University Hospital, AP HP, 47 Boulevard de l Hopital, Paris 75013, France
    Eur Heart J 28:1409-17. 2007
    ..The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account...
  35. doi Dispersion of repolarization and beta-thalassemia major: the prognostic role of QT and JT dispersion for identifying the high-risk patients for sudden death
    Vincenzo Russo
    Chair of Cardiology, Second University of Naples, Naples, Italy
    Eur J Haematol 86:324-31. 2011
    ..The aim of our study was to evaluate the heterogeneity of ventricular repolarization in patients with beta-thalassemia and to test the hypothesis that an abnormal QTc and JTc dispersion may predict SCD in this population...
  36. ncbi Long-term follow-up of arrhythmias in patients with myotonic dystrophy treated by pacing: a multicenter diagnostic pacemaker study
    Arnaud Lazarus
    Service de Cardiologie et de Biostatistique, Hopital Cochin, Paris, France
    J Am Coll Cardiol 40:1645-52. 2002
    ....
  37. pmc Connexin30.2 containing gap junction channels decelerate impulse propagation through the atrioventricular node
    Maria M Kreuzberg
    Institut fur Genetik, Abteilung Molekulargenetik, Universitat Bonn, Romerstrasse 164, 53117 Bonn, Germany
    Proc Natl Acad Sci U S A 103:5959-64. 2006
    ..g., atrial fibrillation) by preventing rapid conduction to the ventricles potentially associated with hemodynamic deterioration...
  38. ncbi Mouse model of SCN5A-linked hereditary Lenègre's disease: age-related conduction slowing and myocardial fibrosis
    Anne Royer
    INSERM U533, Institut du Thorax, Faculte de Medecine, Nantes, France
    Circulation 111:1738-46. 2005
    ..In the present study, we investigated heterozygous Scn5a-knockout mice (Scn5a+/- mice) as a model for hereditary Lenègre's disease...
  39. doi Defining left bundle branch block in the era of cardiac resynchronization therapy
    David G Strauss
    Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am J Cardiol 107:927-34. 2011
    ..Further studies are needed to reinvestigate the electrocardiographic criteria for complete LBBB and the implications of these criteria for selecting patients for CRT...
  40. ncbi Age- and training-dependent development of arrhythmogenic right ventricular cardiomyopathy in heterozygous plakoglobin-deficient mice
    Paulus Kirchhof
    Department of Cardiology and Angiology, Hospital of the University of Muenster, Germany
    Circulation 114:1799-806. 2006
    ..To test the hypothesis that reduced desmosomal protein expression causes ARVC, we studied the cardiac effects of heterozygous plakoglobin deficiency in mice...
  41. pmc Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice
    Vesna Nikolova
    Molecular Cardiology Program, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia
    J Clin Invest 113:357-69. 2004
    ..Despite severe DCM, defects in nuclear function prevent Lmna(-/-) cardiomyocytes from developing compensatory hypertrophy and accelerate disease progression...
  42. ncbi Drug-induced prolongation of the QT interval
    Dan M Roden
    Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    N Engl J Med 350:1013-22. 2004
  43. ncbi The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2
    Baofeng Yang
    Department of Pharmacology State Province Key Laboratories of Biomedicine Pharmaceutics of China, Harbin Medical University, Harbin, Heilongjiang 150086, China
    Nat Med 13:486-91. 2007
    ..1) and GJA1 (which encodes connexin 43), and this likely accounts at least in part for its arrhythmogenic potential. Thus, miR-1 may have important pathophysiological functions in the heart, and is a potential antiarrhythmic target...
  44. ncbi Electrocardiographic abnormalities and sudden death in myotonic dystrophy type 1
    William J Groh
    Department of Medicine, Krannert Institute of Cardiology, Indiana University, Indianapolis 46202, USA
    N Engl J Med 358:2688-97. 2008
    ..Sudden death can occur as a consequence of cardiac-conduction abnormalities in the neuromuscular disease myotonic dystrophy type 1. The determinants of the risk of sudden death remain imprecise...
  45. ncbi Clinical and genetic characterization of families with arrhythmogenic right ventricular dysplasia/cardiomyopathy provides novel insights into patterns of disease expression
    Srijita Sen-Chowdhry
    The Heart Hospital, University College London, United Kingdom
    Circulation 115:1710-20. 2007
    ..We hypothesized that unbiased representation of the spectrum of disease expression in arrhythmogenic right ventricular dysplasia/cardiomyopathy would require in vivo assessment of families in a genetically heterogeneous population...
  46. pmc Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy
    Kalliopi Pilichou
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua, 35121 Padua, Italy
    J Exp Med 206:1787-802. 2009
    ..Insight into mechanisms initiating myocardial damage in ARVC is a prerequisite to the future development of new therapies aimed at delaying onset or progression of the disease...
  47. doi Radiation dose reduction and coronary assessability of prospective electrocardiogram-gated computed tomography coronary angiography: comparison with retrospective electrocardiogram-gated helical scan
    Takao Maruyama
    Department of Cardiology, Kawasaki Hospital, Kobe, Japan
    J Am Coll Cardiol 52:1450-5. 2008
    ....
  48. pmc Prosthetic heart valve assessment with multidetector-row CT: imaging characteristics of 91 valves in 83 patients
    Jesse Habets
    Department of Radiology, UMC Utrecht, P O Box 85500, E01 132, 3508, GA, Utrecht, The Netherlands
    Eur Radiol 21:1390-6. 2011
    ..Multidetector CT (MDCT) has shown potential for prosthetic heart valve (PHV) assessment. We assessed the image quality of different PHV types to determine which valves are suitable for MDCT evaluation...
  49. doi Mutational spectrum in the Ca(2+)--activated cation channel gene TRPM4 in patients with cardiac conductance disturbances
    Birgit Stallmeyer
    Institut für Genetik von Herzerkrankungen, Universitatsklinikum Munster, Munster, Germany
    Hum Mutat 33:109-17. 2012
    ..The phenotypes are variable and clearly suggestive of additional factors modulating the disease phenotype in some patients...
  50. ncbi Assessment of clinical features in transient left ventricular apical ballooning
    Yoshiteru Abe
    Division of Cardiology, Shimada Municipal Hospital, Shimada, Shizuoka, Japan
    J Am Coll Cardiol 41:737-42. 2003
    ..We sought to assess the clinical features of transient left ventricular (LV) apical ballooning...
  51. doi Dry and noncontact EEG sensors for mobile brain-computer interfaces
    Yu Mike Chi
    Department of Electrical and Computer Engineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA 92093, USA
    IEEE Trans Neural Syst Rehabil Eng 20:228-35. 2012
    ..The results of these experiments show that both dry and noncontact electrodes, with further development, may become a viable tool for both future mobile BCI and general EEG applications...
  52. ncbi Prospectively ECG-triggered high-pitch spiral acquisition for coronary CT angiography using dual source CT: technique and initial experience
    Michael Lell
    Diagnostic Radiology, University of Erlangen, Erlangen, Germany
    Eur Radiol 19:2576-83. 2009
    ..We evaluated radiation exposure and image quality of a new coronary CT angiography protocol, high-pitch spiral acquisition, using dual source CT (DSCT)...
  53. ncbi Mechanisms for discordant alternans
    M A Watanabe
    Physics Department, Northeastern University, Boston, Massachusetts 02115, USA
    J Cardiovasc Electrophysiol 12:196-206. 2001
    ..CONCLUSION: Spatial inhomogeneities of electrical restitution properties are not required to produce discordant alternans...
  54. ncbi Prolonged QTc interval predicts mortality in patients with Type 1 diabetes mellitus
    P Rossing
    Steno Diabetes Center, Gentofte, Denmark
    Diabet Med 18:199-205. 2001
    ..To evaluate prolonged QTc interval and QT dispersion as predictors of all-cause and cardiovascular mortality after adjustment for well-established risk factors in Type 1 diabetic patients...
  55. pmc Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the Task Force Criteria
    Frank I Marcus
    University of Arizona, Tucson, AZ, USA
    Eur Heart J 31:806-14. 2010
    ..Consequently, the 1994 criteria were highly specific but lacked sensitivity for early and familial disease...
  56. ncbi Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic
    L M Hondeghem
    Department of Pharmacology, Leuven, Belgium
    Circulation 103:2004-13. 2001
    ..Prolongation of action potential duration (APD) is considered a major antiarrhythmic mechanism (class 2I), but paradoxically, it frequently is also proarrhythmic (torsade de pointes)...
  57. doi Cardiac-resynchronization therapy for mild-to-moderate heart failure
    Anthony S L Tang
    Island Medical Program, University of British Columbia, Vancouver, Canada
    N Engl J Med 363:2385-95. 2010
    ..Most of these patients are candidates for an implantable cardioverter-defibrillator (ICD). We evaluated whether adding CRT to an ICD and optimal medical therapy might reduce mortality and morbidity among such patients...
  58. ncbi Recommendations for interpretation of 12-lead electrocardiogram in the athlete
    Domenico Corrado
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padua Medical School, Via Giustiniani 2, Padova, Italy
    Eur Heart J 31:243-59. 2010
    ..of an international panel of cardiologists and sports medical physicians with expertise in the fields of electrocardiography, imaging, inherited cardiovascular disease, cardiovascular pathology, and management of young competitive ..
  59. doi Technical and organisational feasibility of a multifunctional telemedicine system in an emergency medical service - an observational study
    Sebastian Bergrath
    Emergency Medical Care Section, Department of Anaesthesiology, University Hospital Aachen, RWTH Aachen University, Pauwelsstrasse 30, D 52074 Aachen, Germany
    J Telemed Telecare 17:371-7. 2011
    ..Use of the telemedical system in EMS is feasible and the quality of the transmitted images and video was satisfactory. However, technical reliability and availability need to be improved prior to routine use...
  60. pmc Transient outward current (I(to)) gain-of-function mutations in the KCND3-encoded Kv4.3 potassium channel and Brugada syndrome
    John R Giudicessi
    Department of Medicine Division of Cardiovascular Diseases, Department of Pediatrics Division of Pediatric Cardiology, and Department of Molecular Pharmacology and Experimental Therapeutics, Windland Smith Rice Sudden Death Genomics Laboratory, Mayo Clinic, Rochester, Minnesota, USA
    Heart Rhythm 8:1024-32. 2011
    ..Given the prominent role of the transient outward current (I(to)) in BrS pathogenesis, we hypothesized that rare gain-of-function mutations in KCND3 may serve as a pathogenic substrate for BrS...
  61. ncbi Isolated perfused and paced guinea pig heart to test for drug-induced changes of the QT interval
    Hsien C Cheng
    Safety Pharmacology, Drug Safety Evaluation, Sanofi Aventis, Bridgewater, NJ 08807, USA
    J Pharmacol Toxicol Methods 54:278-87. 2006
    ..Since QT intervals can be generated from paced or spontaneously beating hearts, data so generated can also be used for validating QT(c) correction equations...
  62. doi A prospective study on electrocardiographic findings of patients with organophosphorus poisoning
    Subash Vijayakumar
    Department of Pharmacy Practice, Mahatma Gandhi Memorial Hospital, Vaagdevi College of Pharmacy, Warangal, Andhra Pradesh, India
    Cardiovasc Toxicol 11:113-7. 2011
    ..From this study, we conclude that acute organophosphorus poisoning is associated with ventricular arrhythmias, tachycardia and bradycardia, and attributes mild myocardial ischemia...
  63. doi Comparison of dual-source CT coronary angiography and conventional coronary angiography for detecting coronary artery disease
    Yi Xu
    Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China
    Int J Cardiovasc Imaging 26:75-81. 2010
    ..076). The diagnostic performance of DSCT-CCTA is generally as accurate as that of CAG. Thus, DSCT-CCTA is a reliable non-invasive method for detecting coronary artery stenosis...
  64. ncbi 107th ENMC international workshop: the management of cardiac involvement in muscular dystrophy and myotonic dystrophy. 7th-9th June 2002, Naarden, the Netherlands
    K Bushby
    Department of Neuromuscular Genetics, Institute of Human Genetics, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK
    Neuromuscul Disord 13:166-72. 2003
  65. doi American Heart Association/American College of Cardiology Foundation/Heart Rhythm Society Scientific Statement on Noninvasive Risk Stratification Techniques for Identifying Patients at Risk for Sudden Cardiac Death. A scientific statement from the America
    Jeffrey J Goldberger
    J Am Coll Cardiol 52:1179-99. 2008
  66. ncbi Detecting acute coronary syndrome in the emergency department with cardiac magnetic resonance imaging
    Raymond Y Kwong
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    Circulation 107:531-7. 2003
    ..Managing chest pain in the emergency department remains a challenge with current diagnostic strategies. We hypothesized that cardiac MRI could accurately identify patients with possible or probable acute coronary syndrome...
  67. pmc Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome
    Ahmad S Amin
    Heart Failure Research Center, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    J Clin Invest 118:2552-61. 2008
    ....
  68. ncbi Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart
    Rie Schultz Hansen
    Neurosearch A S, Pederstrupvej 93, 2750 Ballerup, Denmark
    J Pharmacol Exp Ther 321:996-1002. 2007
    ..Taken together, the present data strongly support the concept of using hERG activators as a treatment for certain kinds of arrhythmias and suggest further investigation of this new approach...
  69. ncbi Clinical implications of present physiological understanding of HRV components
    Federico Lombardi
    Cardiologia, Dipartimento di Medicina Chirurgia e Odontoiatria, Osp San Paolo, University of Milan, Milan, Italy
    Card Electrophysiol Rev 6:245-9. 2002
    ....
  70. doi Functional recovery after acute myocardial infarction: comparison between angiography, electrocardiography, and cardiovascular magnetic resonance measures of microvascular injury
    Robin Nijveldt
    Department of Cardiology, VU University Medical Center, Amsterdam, The Netherlands
    J Am Coll Cardiol 52:181-9. 2008
    ....
  71. pmc Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function
    Axel Linke
    Cardiovascular Research Institute, Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    Proc Natl Acad Sci U S A 102:8966-71. 2005
    ..These results suggest that strategies capable of activating the growth reserve of the myocardium may be important in cardiac repair after ischemic injury...
  72. ncbi Sensitive troponin I assay in early diagnosis of acute myocardial infarction
    Till Keller
    Department of Medicine II, University Medical Center, Johannes Gutenberg University, Mainz, Germany
    N Engl J Med 361:868-77. 2009
    ..Cardiac troponin testing is central to the diagnosis of acute myocardial infarction. We evaluated a sensitive troponin I assay for the early diagnosis and risk stratification of myocardial infarction...
  73. ncbi Long QT syndromes and torsade de pointes
    S Viskin
    Department of Cardiology, Sourasky Tel Aviv Medical Center, and Sackler School of Medicine, Tel Aviv University, Israel
    Lancet 354:1625-33. 1999
    ..Mutations causing "silent" forms of congenital LQTS, in which the patient remains free of arrhythmias until exposed to drugs that further impair repolarisation, are now recognised...
  74. pmc Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations
    W H Linda Kao
    Department of Epidemiology, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA
    Circulation 119:940-51. 2009
    ....
  75. ncbi Right ventricular function in patients with acute pulmonary embolism: analysis with electrocardiography-synchronized multi-detector row CT
    Halil Dogan
    Department of Radiology, Leiden University Medical Center, Albinusdreef 2, C2 S, 2333 ZA Leiden, The Netherlands
    Radiology 242:78-84. 2007
    To prospectively assess electrocardiography (ECG)-synchronized multi-detector row computed tomography (CT) for the evaluation of right ventricular (RV) function in patients suspected of having pulmonary embolism (PE).
  76. pmc Unrecognized non-Q-wave myocardial infarction: prevalence and prognostic significance in patients with suspected coronary disease
    Han W Kim
    Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke University, Durham, North Carolina, USA
    PLoS Med 6:e1000057. 2009
    ..However, the diagnosis of UMI is based on the appearance of incidental Q-waves on 12-lead electrocardiography. Thus, the syndrome of non-Q-wave UMI has not been investigated...
  77. doi High prevalence of early repolarization in short QT syndrome
    Hiroshi Watanabe
    Division of Cardiology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
    Heart Rhythm 7:647-52. 2010
    ..It has been reported recently that early repolarization is associated with idiopathic ventricular fibrillation and the QT interval is short in patients with early repolarization...
  78. pmc In vivo studies of Scn5a+/- mice modeling Brugada syndrome demonstrate both conduction and repolarization abnormalities
    Claire A Martin
    Physiological Laboratory, University of Cambridge, Cambridge, United Kingdom
    J Electrocardiol 43:433-9. 2010
    ....
  79. pmc Spatial and temporal heterogeneities are localized to the right ventricular outflow tract in a heterozygotic Scn5a mouse model
    Claire A Martin
    Physiological Laboratory, Department of Biochemistry, University of Cambridge, Downing Site, Cambridge CB2 3EG, UK
    Am J Physiol Heart Circ Physiol 300:H605-16. 2011
    ..Our findings may contribute to future work investigating possible pharmacological treatments for a disease in which the current mainstay of treatment is implantable cardioverter defibrillator implantation...
  80. ncbi ST-segment elevation in conditions other than acute myocardial infarction
    Kyuhyun Wang
    Hennepin County Medical Center, Cardiology Division, University of Minnesota, Minneapolis, MN 55415, USA
    N Engl J Med 349:2128-35. 2003
  81. doi Multivariate short-term heart rate variability: a pre-diagnostic tool for screening heart disease
    Andreas Heitmann
    Department of Medical Engineering and Biotechnology, University of Applied Sciences Jena, Jena, Germany
    Med Biol Eng Comput 49:41-50. 2011
    ..Multivariate short-term HRV, analyzed by both linear and nonlinear methods appears to be a suitable pre-diagnostic tool for screening heart disease in primary care settings...
  82. doi Assessment of interventricular and right-intraventricular dyssynchrony in patients with surgically repaired tetralogy of Fallot by two-dimensional speckle tracking
    Matthias Mueller
    Department of Paediatric Cardiology, Saarland University Hospital, Kirrberger Strase, 66421 Homburg Saar, Germany
    Eur J Echocardiogr 11:786-92. 2010
    ..We aimed to assess interventricular and right-intraventricular dyssynchrony in patients after tetralogy of Fallot (TOF) repair by two-dimensional (2D) speckle tracking and to identify factors associated with dyssynchrony...
  83. ncbi Normal electrocardiography and serum troponin I levels preclude the presence of clinically significant blunt cardiac injury
    George C Velmahos
    Department of Surgery, University of Southern California, and the Los Angeles County and University of Southern California LAC USC Medical Center, Los Angeles, CA 90033, USA
    J Trauma 54:45-50; discussion 50-1. 2003
    ..The purpose of this study was to examine whether the combination of two simple tests, electrocardiography (ECG) and serum troponin I (TnI) level, may serve as reliable predictors of BCI or the absence of it.
  84. pmc Acute ECG ST-segment elevation mimicking myocardial infarction in a patient with pulmonary embolism
    Tomaž Goslar
    Clinical Department for Internal Intensive Care, University Medical Center Ljubljana, Slovenia
    Cardiovasc Ultrasound 8:50. 2010
    ....
  85. pmc State-of-the-art CT imaging techniques for congenital heart disease
    Hyun Woo Goo
    Department of Radiology and the Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138 736, Korea
    Korean J Radiol 11:4-18. 2010
    ....
  86. ncbi The relationship between high resting heart rate and ventricular arrhythmogenesis in patients referred to ambulatory 24 h electrocardiographic recording
    Elsayed Z Soliman
    Department of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston Salem, NC 27104, USA
    Europace 12:261-5. 2010
    ..Ventricular arrhythmia is the most common antecedent event before SCD. Examining associations between resting HR and ventricular arrhythmogenesis may enhance our understanding of the association between high resting HR and SCD...
  87. ncbi A patient-adapting heartbeat classifier using ECG morphology and heartbeat interval features
    Philip de Chazal
    BiancaMed Ltd, NovaUCD, Belfield Innovation Park, University College Dublin, Belfield Dublin 4, Ireland
    IEEE Trans Biomed Eng 53:2535-43. 2006
    ..This study illustrates the ability to provide highly beneficial automatic arrhythmia monitoring and is an improvement on previously reported results for automated heartbeat classification systems...
  88. ncbi Incidence of recognized and unrecognized myocardial infarction in men and women aged 55 and older: the Rotterdam Study
    Anneke De Torbal
    Department of Epidemiology and Biostatistics, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Eur Heart J 27:729-36. 2006
    ..Contemporary data on the incidence of unrecognized myocardial infarction (MI) among subjects aged 55 and older are limited...
  89. ncbi Aging and nonlinear heart rate control in a healthy population
    Frank Beckers
    Laboratory of Experimental Cardiology, School of Medicine, Katholieke Universiteit Leuven, UZ Gasthuisberg O N, Herestraat 49, B 3000 Leuven, Belgium
    Am J Physiol Heart Circ Physiol 290:H2560-70. 2006
    ..No clear difference between men and women was found in the nonlinear indexes. Nonlinear indexes decline with age. This can be related to the concept of decreasing autonomic modulation with advancing age...
  90. ncbi Cardiac resynchronization with sequential biventricular pacing for the treatment of moderate-to-severe heart failure
    Angel R Leon
    Carlyle Fraser Heart Center Division of Cardiology, Emory University, Atlanta, Georgia, USA
    J Am Coll Cardiol 46:2298-304. 2005
    ..The InSync III study evaluated sequential cardiac resynchronization therapy (CRT) in patients with moderate-to-severe heart failure and prolonged QRS...
  91. ncbi Reviewing myocardial silent ischemia: specific patient subgroups
    Theodoros Xanthos
    Department of Experimental Surgery and Surgical Research N S Christeas, Athens School of Medicine, Athens, Greece
    Int J Cardiol 124:139-48. 2008
    ....
  92. ncbi Evaluation of electrocardiographic and hemodynamic effects of caffeine with acute dosing in healthy volunteers
    R Ammar
    University of Connecticut School of Pharmacy, Storrs, USA
    Pharmacotherapy 21:437-42. 2001
    ....
  93. ncbi QTc interval and resting heart rate as long-term predictors of mortality in type 1 and type 2 diabetes mellitus: a 23-year follow-up
    C Stettler
    Division of Endocrinology and Diabetes, University of Bern, Inselspital, CH 3010, Bern, Switzerland
    Diabetologia 50:186-94. 2007
    ..We evaluated the association of QT interval corrected for heart rate (QT(c)) and resting heart rate (rHR) with mortality (all-causes, cardiovascular, cardiac, and ischaemic heart disease) in subjects with type 1 and type 2 diabetes...
  94. ncbi Autologous bone marrow stem cell mobilization induced by granulocyte colony-stimulating factor after subacute ST-segment elevation myocardial infarction undergoing late revascularization: final results from the G-CSF-STEMI (Granulocyte Colony-Stimulating
    Markus G Engelmann
    Medical Clinic I Department of Cardiology, Ludwig Maximilians University, Klinikum Grosshadern, Munich, Germany
    J Am Coll Cardiol 48:1712-21. 2006
    ....
  95. ncbi Value of acute rest sestamibi perfusion imaging for evaluation of patients admitted to the emergency department with chest pain
    M C Kontos
    Medical College of Virginia Virginia Commonwealth University, Richmond 23298 0128, USA
    J Am Coll Cardiol 30:976-82. 1997
    ....
  96. ncbi QT dispersion: comparison between diabetic and non-diabetic individuals and correlation with cardiac autonomic neuropathy
    Michael Psallas
    First Department of Propaedeutic Medicine, Athens University, Laiko Hospital, Athens, Greece
    Hellenic J Cardiol 47:255-62. 2006
    ..The aim of this study was to investigate: 1) the differences in QTd between diabetics and non-diabetics; 2) the differences in QTd between those with type 1 and type 2 diabetes; 3) the relation between QTd and CAN...
  97. ncbi Calculation of effective VV interval facilitates optimization of AV delay and VV interval in cardiac resynchronization therapy
    Kevin Vernooy
    Department of Physiology, Maastricht University, Maastricht, The Netherlands
    Heart Rhythm 4:75-82. 2007
    ..The optimal combination of AV delay and VV interval currently is determined by extensive hemodynamic testing...
  98. ncbi A prospective comparison of AV delay programming methods for hemodynamic optimization during cardiac resynchronization therapy
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Cardiovasc Electrophysiol 18:490-6. 2007
    ..The present study was designed to compare the acute effects of AVD programming methods during CRT...
  99. ncbi Q-wave prediction of myocardial infarct location, size and transmural extent at magnetic resonance imaging
    Daniele Rovai
    CNR, Clinical Physiology, Italy
    Coron Artery Dis 18:381-9. 2007
    ..We investigated how pathologic Q waves or equivalents predict location, size and transmural extent of myocardial infarction (MI)...
  100. ncbi P-wave durations in patients experiencing atrial fibrillation during exercise testing
    Ozcan Ozdemir
    Turkiye Yuksek Ihtisas Hospital, Cardiology Clinics, Ankara, Turkey
    Angiology 58:97-101. 2007
    ..Furthermore, treatment of these patients with beta blockers would appear to decrease the recurrence of exercise-induced AF and to be associated with a decrease in P-wave durations...
  101. doi Diagnosis of paroxysmal atrial fibrillation in patients with implanted pacemakers: relationship to symptoms and other variables
    Gianluca Quirino
    Ivrea Hospital, Ivrea, Italy
    Pacing Clin Electrophysiol 32:91-8. 2009
    ..The study prospectively evaluated the burden of asymptomatic AF episodes in pacemaker patients (for sick sinus syndrome) with a history of documented paroxysmal AF...

Research Grants80

  1. Update and modification of Task Force Criteria for ARVD/C
    Frank Marcus; Fiscal Year: 2007
    ..several members from the original Task Force on ARVD/C, and current experts in the imaging modalities, electrocardiography and pathology who have a major interest in ARVD/C...
  2. Autonomic consequences of brief seizures
    Mark Stewart; Fiscal Year: 2004
    ..abstract_text> ..
  3. STATISITICAL DESIGN, MONITORING &COORD. OF VISION CLINICAL TRIALS &EPIDEMIOLOGY
    Keri Hammel; Fiscal Year: 2012
    ..Also, there will be a measurement of pressure in the eye and thickness of the cornea. To study patients'DNA, the researchers will obtain a bloo..
  4. ECG-derived cardiopulmonary coupling biomarkers of sleep, sleep-breathing, and ca
    Robert Thomas; Fiscal Year: 2009
    ..We propose to show its usefulness as a monitor of sleep in health, in those with simple and complicated forms of sleep apnea, and in patients with heart failure. ..
  5. ECG-derived cardiopulmonary coupling biomarkers of sleep, sleep-breathing, and ca
    Robert J Thomas; Fiscal Year: 2010
    ..We propose to show its usefulness as a monitor of sleep in health, in those with simple and complicated forms of sleep apnea, and in patients with heart failure. ..
  6. MOLECULAR BASIS FOR DRUG INDUCED CARDIOTOXICITY IN AIDS
    CRAIG CLARKSON; Fiscal Year: 2000
    ....
  7. MOLECULAR BASIS FOR DRUG INDUCED CARDIOTOXICITY IN AIDS
    CRAIG CLARKSON; Fiscal Year: 2001
    ....
  8. MOLECULAR BASIS FOR DRUG INDUCED CARDIOTOXICITY IN AIDS
    CRAIG CLARKSON; Fiscal Year: 1999
    ....
  9. Autonomic consequences of brief seizures
    Mark Stewart; Fiscal Year: 2003
    ..abstract_text> ..
  10. Betahistine: Novel Therapeutic in Attention Deficit Hyperactivity Disorder
    CHARLES PIERCE; Fiscal Year: 2009
    ..This Phase 1 SBIR proposal will determine the safety, tolerability, and pharmacokinetics of higher doses of betahistine and characterize dose-response for improving attention and impulsivity in young adults with ADHD. ..
  11. ARRHYTHMOGENIC ACTIONS OF ANTIHISTAMINES
    Raymond Woosley; Fiscal Year: 1999
    ..This information will enable physicians to identify patients at risk for adverse response to these actions. Also, the appropriate treatment of patients with intentional or accidental overdose of antihistamines can be determined. ..
  12. IDENTIFYING HIGH RISK PATIENTS WITH SYNCOPE
    Wishwa Kapoor; Fiscal Year: 1990
    ..Furthermore, these models will lead to future studies investigating the impact of various treatment interventions in these high risk groups...
  13. Screening for Jervell and Lange-Nielsen Syndrome
    Ruey Kang Chang; Fiscal Year: 2009
    ..We propose an innovative approach to early diagnosis of JLNS by cardiac screening of all infants who are identified with sensorineural hearing loss by the California Newborn Hearing Screening Program. ..
  14. Screening for Jervell and Lange-Nielsen Syndrome
    Ruey Kang R Chang; Fiscal Year: 2010
    ..We propose an innovative approach to early diagnosis of JLNS by cardiac screening of all infants who are identified with sensorineural hearing loss by the California Newborn Hearing Screening Program. ..
  15. Update and modification of Task Force Criteria for ARVD/C
    Frank Marcus; Fiscal Year: 2006
    ..several members from the original Task Force on ARVD/C, and current experts in the imaging modalities, electrocardiography and pathology who have a major interest in ARVD/C...
  16. EXPERIMENTAL MODEL OF NEUROGENIC HYPERTENSION
    PETER JANNETTA; Fiscal Year: 1980
    ..In chronic experiments hemodynamic changes in the unanesthesized animal, and possible establishment of permanent hypertension will be studied. Finally, anatomic (Text Truncated -Exceeds Capacity)..
  17. NURSING STRATEGY FOR CARDIAC ISCHEMIA MONITORING
    Barbara Drew; Fiscal Year: 1993
    ..The contingency table will be analyzed under a non-parametric "correlated proportions" statistical model. The Stuart extension of the McNemar test will be used to test for the equality of the correlated marginal probabilities...
  18. PROMISE Trial: Clinical Coordinating Center
    Pamela Susan Douglas; Fiscal Year: 2012
    ..testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest pain, and will reduce the composite primary ..
  19. PROMISE Trial: EQOL Coordinating Center
    Daniel B Mark; Fiscal Year: 2010
    ..testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest pain, and will reduce the composite primary ..
  20. PROMISE Trial: SDCC
    Kerry L Lee; Fiscal Year: 2010
    ..testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest pain, and will reduce the composite primary ..
  21. PROMISE Trial: Dx Core
    Udo Hoffmann; Fiscal Year: 2010
    ..testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest pain, and will reduce the composite primary ..
  22. PROMISE Trial: Dx Core
    Udo Hoffmann; Fiscal Year: 2009
    ..testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest pain, and will reduce the composite primary ..
  23. PROMISE Trial: Clinical Coordinating Center
    Pamela Susan Douglas; Fiscal Year: 2010
    ..testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest pain, and will reduce the composite primary ..
  24. PROMISE Trial: SDCC
    Kerry Lee; Fiscal Year: 2009
    ..testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest pain, and will reduce the composite primary ..
  25. PROMISE Trial: Clinical Coordinating Center
    Pamela Douglas; Fiscal Year: 2009
    ..testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest pain, and will reduce the composite primary ..
  26. PROMISE Trial: EQOL Coordinating Center
    Daniel Mark; Fiscal Year: 2009
    ..testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest pain, and will reduce the composite primary ..
  27. AUTONOMIC FUNCTION AND POSTTRANSPLANT QUALITY OF LIFE
    Donna Hathaway; Fiscal Year: 1999
    ....
  28. IDIOPATHIC DILATED CARDIOMYOPATHY
    Virginia Michels; Fiscal Year: 1991
    ..Medical histories of 1st degree relatives will be obtained; these relatives will be studied by electrocardiography and M-mode, 2-dimensional, and Doppler echocardiography and will have levels of ANP determined...
  29. IDIOPATHIC DILATED CARDIOMYOPATHY
    Virginia Michels; Fiscal Year: 1990
    ..Medical histories of 1st degree relatives will be obtained; these relatives will be studied by electrocardiography and M-mode, 2-dimensional, and Doppler echocardiography and will have levels of ANP determined...
  30. GENERAL CLINICAL RESEARCH CENTER
    CECIL SAMUELSON; Fiscal Year: 1990
    ..hereditary nephritis, congenital adrenal hyperplasia, and Huntington's chorea; the development of improved electrocardiography; the enzymatic basis for acute intermittent porphyria; the therapeutic effectiveness of plasmaphoresis in ..
  31. PROGNOSTIC IMPORTANCE OF MYOCARDIAL ISCHEMIA
    Andrew Selwyn; Fiscal Year: 1993
    ..If the activity of ischemia affects prognosis, it may not be sufficient to treat symptoms alone and new goals may be necessary that aim to control all active ischemia during daily life...
  32. PROGNOSTIC IMPORTANCE OF MYOCARDIAL ISCHEMIA
    Andrew Selwyn; Fiscal Year: 1990
    ..If the activity of ischemia affects prognosis, it may not be sufficient to treat symptoms alone and new goals may be necessary that aim to control all active ischemia during daily life...
  33. FUNCTIONAL CHARACTERISTICS OF THE LEFT HEART
    HAROLD DODGE; Fiscal Year: 1990
    ..Factors influencing the rate of lysis and rethrombosis following thrombolytic therapy are being identified...
  34. Prevention and Risk Identification of SUDEP Mortality - the PRISM Project
    Samden Lhatoo; Fiscal Year: 2011
    ..and analysis of very large datasets of multi-modal seizure data (video, electroencephalography (EEG), electrocardiography (EKG), blood pressure, O2 &CO2 measurements, sleep data);traditional visual and statistical analyses of ..
  35. Bupropion VS Placebo to Treat Pathological Gambling
    Donald Black; Fiscal Year: 2003
    ..abstract_text> ..
  36. Bupropion VS Placebo to Treat Pathological Gambling
    Donald Black; Fiscal Year: 2002
    ..abstract_text> ..
  37. DYNAMICS OF RETINOPATHY AMONG MEXICAN AMERICAN DIABETICS
    Craig Hanis; Fiscal Year: 1990
    ..Such results will suggest intermediate points at which intervention could be aimed to alter the progression and lessen the impact of retinopathy...
  38. Bupropion VS Placebo to Treat Pathological Gambling
    Donald Black; Fiscal Year: 2004
    ..abstract_text> ..
  39. DIAGNOSIS OF CHEST PAIN AND CARE IN RURAL HOSPITALS
    John Westfall; Fiscal Year: 2000
    ..abstract_text> ..
  40. Point Process Models of Human Heart Beat Interval Dynamics
    Riccardo Barbieri; Fiscal Year: 2010
    ..The health implications of this project are a more accurate characterization of cardiovascular control in research and clinical studies of both normal and pathological conditions. ..
  41. Point Process Models of Human Heart Beat Interval Dynamics
    Riccardo Barbieri; Fiscal Year: 2009
    ..The health implications of this project are a more accurate characterization of cardiovascular control in research and clinical studies of both normal and pathological conditions. ..
  42. Point Process Models of Human Heart Beat Interval Dynamics
    Riccardo Barbieri; Fiscal Year: 2007
    ..The health implications of this project are a more accurate characterization of cardiovascular control in research and clinical studies of both normal and pathological conditions. ..
  43. FATTY ACID ANTIARRYTHMIA TRIAL (FAAT)
    Alexander Leaf; Fiscal Year: 1999
    ..We have been developing the protocol for this study for the past three years while establishing the evidence in the laboratory that these n-3 PUFAs are potent antiarrhythmic agents. ..
  44. MODULATION OF CARDIAC REPOLARIZATION
    Dan M Roden; Fiscal Year: 2012
    ..This research focuses on how genetic variation in key molecules controlling normal heart behavior makes people more or less susceptible to serious heart rhythm abnormalities. ..
  45. Efficacy of an Acute Exercise Intervention for Side Effects of SSRIs
    Tierney K Ahrold; Fiscal Year: 2010
    ..This knowledge may help doctors advise and treat patients who take these drugs, and may help scientists create new drugs with mitigated side effect profiles. ..
  46. Efficacy of an Acute Exercise Intervention for Side Effects of SSRIs
    Tierney Ahrold; Fiscal Year: 2009
    ..This knowledge may help doctors advise and treat patients who take these drugs, and may help scientists create new drugs with mitigated side effect profiles. ..
  47. AUTONOMIC NERVOUS SYSTEM FUNCTIONING IN THE HUMAN FETUS
    Lynn Groome; Fiscal Year: 1999
    ....
  48. HIGH RESOLUTION ELECTROCARDIOGRAMS AND ARRHYTHMIA RISK
    EDWARD BERBARI; Fiscal Year: 1990
    High resolution electrocardiography (HRECG) is used to record electrical activity from diseased and/or damaged regions of the myocardium. These potentials are at the end of the QRS and extend into the ST segment...
  49. MASSAGE THERAPY FOR PATIENTS WITH HIV-1
    Thomas Birk; Fiscal Year: 1993
    ..A four by two design utilizing analysis of variance (ANOVA) with repeated measures will be used for statistical treatment of the data. The 0.05 level of significance will be used to reject the null hypothesis. ..
  50. Movement-Responsive Cage for Simultaneous Pharmacology Studies in MiniPigs
    Douglas Mann; Fiscal Year: 2007
    ..programmed dosing, and physiological data acquisition modules for core body temperature, blood pressure and electrocardiography. In accordance with the intent of the SBIR program, the ultimate objective is an instrument that can be ..
  51. EMS Based TIPI-IS Cardiac Care QI/Error Reduction System
    HARRY SELKER; Fiscal Year: 2004
    ....
  52. EMS Based TIPI-IS Cardiac Care QI/Error Reduction System
    HARRY SELKER; Fiscal Year: 2005
    ....
  53. EMS Based TIPI-IS Cardiac Care QI/Error Reduction System
    HARRY SELKER; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  54. INSULIN, INSULIN RESISTANCE, HYPERGLYCEMIA AND CARDIOVAS
    Mohammed Saad; Fiscal Year: 1993
    ....
  55. INSULIN, INSULIN RESISTANCE, HYPERGLYCEMIA AND CARDIOVAS
    Mohammed Saad; Fiscal Year: 1992
    ....
  56. INSULIN, INSULIN RESISTANCE, HYPERGLYCEMIA AND CARDIOVAS
    Mohammed Saad; Fiscal Year: 1991
    ....
  57. Rituximab Therapy in Refractory Adult and Juvenile IIM
    CHARLES ODDIS; Fiscal Year: 2009
    ..abstract_text> ..
  58. Rituximab Therapy in Refractory Adult and Juvenile IIM
    CHARLES ODDIS; Fiscal Year: 2010
    ..abstract_text> ..
  59. CARDIAC AUTONOMIC CONTROL IN CHILDREN OF HIV+ MOTHERS
    Steven Lipshultz; Fiscal Year: 1992
    ....
  60. CARDIAC AUTONOMIC CONTROL IN CHILDREN OF HIV+ MOTHERS
    Steven Lipshultz; Fiscal Year: 1993
    ....
  61. Three-dimensional cardiac accelerometry for cardiac monitoring
    Michael J Russell; Fiscal Year: 2010
    ..The cardiac stress test is the standard screening tool for assessing cardiac function, and electrocardiography (ECG), ultrasound (echocardiography, ECHO) and nuclear myocardial perfusion imaging (MPI) are the ..
  62. Dynamic ECG Predictors of Sudden Cardiac Death in Ischemia Cardiomyopathy
    Mary Carey; Fiscal Year: 2007
    ..Thus, the candidates' strengths in electrocardiography prepare her well for the proposal while expanding her expertise to analyze repolarization abnormalities in ..
  63. Dynamic ECG Predictors of Sudden Cardiac Death in Ischemia Cardiomyopathy
    Mary Carey; Fiscal Year: 2006
    ..Thus, the candidates' strengths in electrocardiography prepare her well for the proposal while expanding her expertise to analyze repolarization abnormalities in ..
  64. Dynamic ECG Predictors of Sudden Cardiac Death
    Mary Carey; Fiscal Year: 2005
    ..Thus, the candidates' strengths in electrocardiography prepare her well for the proposal while expanding her expertise to analyze repolarization abnormalities in ..
  65. Exercise Stress Cardiovascular Magnetic Resonance
    ORLANDO PAUL contact SIMONETTI; Fiscal Year: 2010
    ..affords for the first time measurement of myocardial perfusion, diastolic function, systolic function, electrocardiography, myocardial edema and exertional symptoms - the complete ischemic cascade - in one test...
  66. TIME-INSENSITIVE PREDICTIVE INSTRUMENT IMPACT TRIAL
    HARRY SELKER; Fiscal Year: 1993
    ..S. EDs with symptoms suggestive of ACI and will provide a model of medical practice improvement applicable to many other clinical problems...
  67. Subcellular Origin of T-wave Alternans in the Beating Mouse Heart
    Ariel L Escobar; Fiscal Year: 2010
    ..The resulting transmural difference in AP repolarization creates the TW-Alt observed in the ECG waveform. ..
  68. Subcellular Origin of T-wave Alternans in the Beating Mouse Heart
    ARIEL ESCOBAR; Fiscal Year: 2007
    ..The resulting transmural difference in AP repolarization creates the TW-Alt observed in the ECG waveform. ..
  69. Novel Pharmacological Strategies in Autism
    Christopher McDougle; Fiscal Year: 2005
    ..Phase II (following 6 months of aripiprazole monotherapy). ..
  70. Subcellular Origin of T-wave Alternans in the Beating Mouse Heart
    ARIEL ESCOBAR; Fiscal Year: 2009
    ..The resulting transmural difference in AP repolarization creates the TW-Alt observed in the ECG waveform. ..
  71. Novel Pharmacological Strategies in Autism
    Christopher McDougle; Fiscal Year: 2009
    ..Phase II (following 6 months of aripiprazole monotherapy). ..
  72. Novel Pharmacological Strategies in Autism
    Christopher McDougle; Fiscal Year: 2006
    ..Phase II (following 6 months of aripiprazole monotherapy). ..
  73. MODEL BASED INTERPRETATION OF INTRACARDIAC ELECTROGRAMS
    David Tong; Fiscal Year: 2000
    ....
  74. MODEL BASED INTERPRETATION OF INTRACARDIAC ELECTROGRAMS
    David Tong; Fiscal Year: 1999
    ....