digestive system diagnostic techniques

Summary

Summary: Methods and procedures for the diagnosis of diseases or dysfunction of the digestive system or its organs or demonstration of their physiological processes.

Top Publications

  1. ncbi Methods for measurement of gastric motility
    Lawrence A Szarka
    Clinical Enteric Neuroscience Translational and Epidemiological Research, Mayo Clinic, Charlton 8 110, 200 First St S W, Rochester, MN 55905, USA
    Am J Physiol Gastrointest Liver Physiol 296:G461-75. 2009
  2. ncbi Time and time-frequency characterization of dual-axis swallowing accelerometry signals
    J Lee
    Department of Electrical and Computer Engineering, University of Toronto, Toronto, Canada
    Physiol Meas 29:1105-20. 2008
  3. ncbi Gastric bile monitoring: an in vivo and in vitro study of Bilitec reliability
    L Tibbling Grahn
    Dept of Surgery, University Hospital, Linkoping, Sweden
    Scand J Gastroenterol 37:1334-7. 2002
  4. ncbi The role of transsphincteric pressure and proximal gastric volume in acid reflux before and after fundoplication
    Robert C H Scheffer
    Gastrointestinal Research Unit, Department of Gastroenterology and Department of Surgery, University Medical Center, Utrecht, The Netherlands
    Gastroenterology 129:1900-9. 2005
  5. ncbi Chronic cough: practical considerations
    Susan M Harding
    Chest 123:659-60. 2003
  6. ncbi Chronic cough and gastroesophageal reflux disease: experience with specific therapy for diagnosis and treatment
    Robert H Poe
    Pulmonary Unit, Highland Hospital, Strong Health System, Rochester, NY 14620, USA
    Chest 123:679-84. 2003
  7. ncbi Contribution of sensitivity, volume and tone to visceral perception in the upper gastrointestinal tract in man: emphasis on testing
    H Gregersen
    Center for Visceral Biomechanics and Pain, Aalborg Hospital and University, Aalborg, Denmark
    Neurogastroenterol Motil 19:47-61. 2007
  8. ncbi Transient lower esophageal sphincter relaxations (TLESRs) are the major mechanism of gastroesophageal reflux but are not the cause of reflux disease
    Katsuhiko Iwakiri
    Third Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    Dig Dis Sci 50:1072-7. 2005
  9. ncbi Is proton pump inhibitor testing an effective approach to diagnose gastroesophageal reflux disease in patients with noncardiac chest pain?: a meta-analysis
    Wei Hong Wang
    Department of Gastroenterology, Peking University First Hospital, Beijing, China
    Arch Intern Med 165:1222-8. 2005
  10. ncbi Prospective evaluation of laparoscopic and open 360 degree fundoplication in mild and severe gastro-oesophageal reflux disease
    Thomas Franzén
    Department of Surgery, University Hospital, Linkoping, Sweden
    Eur J Surg 168:539-45. 2002

Research Grants

Detail Information

Publications115 found, 100 shown here

  1. ncbi Methods for measurement of gastric motility
    Lawrence A Szarka
    Clinical Enteric Neuroscience Translational and Epidemiological Research, Mayo Clinic, Charlton 8 110, 200 First St S W, Rochester, MN 55905, USA
    Am J Physiol Gastrointest Liver Physiol 296:G461-75. 2009
    ..The rationale for testing, the relative strengths and weaknesses of each test, and technical details are summarized. We also briefly indicate the applications and validations of the tests for use in experimental animal studies...
  2. ncbi Time and time-frequency characterization of dual-axis swallowing accelerometry signals
    J Lee
    Department of Electrical and Computer Engineering, University of Toronto, Toronto, Canada
    Physiol Meas 29:1105-20. 2008
    ..Therefore, it was concluded that the two axes contain different information about swallowing and that the superior-inferior axis should be further investigated in future swallowing accelerometry studies...
  3. ncbi Gastric bile monitoring: an in vivo and in vitro study of Bilitec reliability
    L Tibbling Grahn
    Dept of Surgery, University Hospital, Linkoping, Sweden
    Scand J Gastroenterol 37:1334-7. 2002
    ..The aim was to study the reliability of the Bilitec 2001 method inmonitoring the presence of bile in repeated tests and at different pH and water dilutions...
  4. ncbi The role of transsphincteric pressure and proximal gastric volume in acid reflux before and after fundoplication
    Robert C H Scheffer
    Gastrointestinal Research Unit, Department of Gastroenterology and Department of Surgery, University Medical Center, Utrecht, The Netherlands
    Gastroenterology 129:1900-9. 2005
    ....
  5. ncbi Chronic cough: practical considerations
    Susan M Harding
    Chest 123:659-60. 2003
  6. ncbi Chronic cough and gastroesophageal reflux disease: experience with specific therapy for diagnosis and treatment
    Robert H Poe
    Pulmonary Unit, Highland Hospital, Strong Health System, Rochester, NY 14620, USA
    Chest 123:679-84. 2003
    ..To evaluate experience using a therapeutic trial of proton-pump inhibitor therapy with or without a prokinetic agent in diagnosis and treatment of gastroesophageal reflux disease (GERD)-related cough...
  7. ncbi Contribution of sensitivity, volume and tone to visceral perception in the upper gastrointestinal tract in man: emphasis on testing
    H Gregersen
    Center for Visceral Biomechanics and Pain, Aalborg Hospital and University, Aalborg, Denmark
    Neurogastroenterol Motil 19:47-61. 2007
    ..It also summarizes the contributions of these techniques towards identifying the components responsible for the generation of upper GI symptoms...
  8. ncbi Transient lower esophageal sphincter relaxations (TLESRs) are the major mechanism of gastroesophageal reflux but are not the cause of reflux disease
    Katsuhiko Iwakiri
    Third Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    Dig Dis Sci 50:1072-7. 2005
    ..These findings, therefore, indicate that reflux disease is not a disorder of TLESRs and relates more to the proximal extent of the refluxate...
  9. ncbi Is proton pump inhibitor testing an effective approach to diagnose gastroesophageal reflux disease in patients with noncardiac chest pain?: a meta-analysis
    Wei Hong Wang
    Department of Gastroenterology, Peking University First Hospital, Beijing, China
    Arch Intern Med 165:1222-8. 2005
    ..Results of studies evaluating the accuracy of a proton pump inhibitor (PPI) treatment as a diagnostic test for GERD-related NCCP have varied. We evaluated the overall accuracy of this modality...
  10. ncbi Prospective evaluation of laparoscopic and open 360 degree fundoplication in mild and severe gastro-oesophageal reflux disease
    Thomas Franzén
    Department of Surgery, University Hospital, Linkoping, Sweden
    Eur J Surg 168:539-45. 2002
    ..To investigate the relationship between five-year control of reflux and early postoperative oesophageal function after total fundoplication done either laparoscopically or through a laparotomy in severe and mild reflux disease...
  11. ncbi Globus sensation and gastroesophageal reflux
    Julia M Chevalier
    Service d ORL et Chirurgie Cervico Faciale, Centre Hospitalier Universitaire Vaudois CHUV, Rue du Bugnon 46, 1011 Lausanne, Switzerland
    Eur Arch Otorhinolaryngol 260:273-6. 2003
    ..Ten out of 13 patients improved with treatment. This study suggests that globus may be associated with reflux, and acidity does not have to reach the pharynx to produce globus sensation...
  12. ncbi Esophageal function testing: role of combined multichannel intraluminal impedance and manometry
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, 210 CSB, Charleston, SC 29425, USA
    Gastrointest Endosc Clin N Am 15:265-75. 2005
    ....
  13. ncbi Multicenter, prospective, double-blind, randomized trial of laparoscopic nissen vs anterior 90 degrees partial fundoplication
    David I Watson
    Department of Surgery, k Flinders University of South Australia, Adelaide, Australia
    Arch Surg 139:1160-7. 2004
    ..Laparoscopic anterior 90 degrees partial fundoplication for gastroesophageal reflux is associated with a lower incidence of postoperative dysphagia and other adverse effects compared with laparoscopic Nissen fundoplication...
  14. ncbi Obesity and gastro-esophageal acid reflux: physiopathological mechanisms and role of gastric bariatric surgery
    Vincenzo Di Francesco
    Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
    Obes Surg 14:1095-102. 2004
    ..The aims of this study were to evaluate esophageal motility and gastro-esophageal acid circadian patterns in obese patients and to test the effects of vertical banded gastroplasty (VBG) on these parameters...
  15. ncbi The proton pump inhibitor (PPI) test in GERD: does it still have a role?
    Anita Gasiorowska
    The Neuroenteric Clinical Research Group, Section of Gastroenterology, Department of Medicine, Southern Arizona VA Health Care System and Arizona Health Sciences Center, Tucson, AZ
    J Clin Gastroenterol 42:867-74. 2008
    ..Although the results were conflicting, the PPI test remains a popular tool for determining the presence of GERD. Attempts to challenge the PPI test without offering attractive alternatives are unlikely to alter clinical practice...
  16. ncbi Acid, weakly acidic and non-acid gastro-oesophageal reflux: differences, prevalence and clinical relevance
    Daniel Sifrim
    Centre for Gastroenterological Research, Catholic University of Leuven, Belgium
    Eur J Gastroenterol Hepatol 16:823-30. 2004
    ..This review will focus on definition, detection, pathophysiology and symptom association of weakly acidic and non-acid reflux, in both adult and paediatric populations...
  17. ncbi Laryngitis and gastroesophageal reflux disease: increasing prevalence or poor diagnostic tests?
    Michael F Vaezi
    Am J Gastroenterol 99:786-8. 2004
    ..GERD may be one cause of laryngeal signs and symptoms in a subgroup of patients but not in all those currently so suspected. Future, studies are needed in this area to better delineate this association...
  18. ncbi [Bernstein test]
    Yoshitaka Konda
    Higashiyama Takeda Hospital
    Nihon Rinsho 65:884-9. 2007
    ..Both as the theoretical basis of acid induced esophageal pain and as clinical method of measuring acid sensitivity in esophagus, Bernstein test should be recalled frequently and improved further...
  19. ncbi [Esophageal pH monitoring]
    Takafumi Yamamoto
    Department of Digestive and Life style Related Disease, Kagoshima University Graduate School of Medical and Dental Sciences
    Nihon Rinsho 65:877-83. 2007
    ..The widespread usage of pH monitoring system is expected to give us the new knowledge of GERD, NERD and GERD associated diseases...
  20. ncbi Impact of antireflux operation on columnar-lined esophagus
    Jean Yves Mabrut
    Department of Digestive Surgery and Liver Transplantation, Croix Rousse Hospital, Lyon, France
    J Am Coll Surg 196:60-7. 2003
    ..The aim of this study was to assess a single center's experience and review the literature on the impact of antireflux operation on CLE without high-grade dysplasia...
  21. ncbi Diagnostic modalities for gastroesophageal reflux
    A K Patwari
    Department of Pediatrics LHMC and Associated Kalawati Saran Children s Hospital, New Delhi, India
    Indian J Pediatr 69:133-6. 2002
    ..To evaluate commonly utilized diagnostic modalities to detecting Gastroesophageal Reflux (GER)...
  22. ncbi Sustained esophageal contraction: a motor correlate of heartburn symptom
    N Pehlivanov
    Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Am J Physiol Gastrointest Liver Physiol 281:G743-51. 2001
    ..3%) Bernstein-negative tests (P = 0.04). We conclude that a SEC precedes both spontaneous and induced heartburn symptoms and may be the cause of heartburn sensation...
  23. ncbi A new optics-based gastroesophageal reflux probe
    Milton P Macedo
    Electronics and Instrumentation Group, Department of Physics, University of Coimbra, Portugal
    Technol Health Care 10:147-60. 2002
    ..Our results show the capability of this new technique to make the identification of GOR episodes...
  24. ncbi Combined multichannel intraluminal impedance and pH esophageal testing compared to pH alone for diagnosing both acid and weakly acidic gastroesophageal reflux
    Amine Hila
    Department of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina, USA
    Clin Gastroenterol Hepatol 5:172-7. 2007
    ..The aim of this study was to assess the accuracy of pH monitoring alone in detecting acid reflux and WAR compared with MII-pH...
  25. ncbi [Gastroenterological function tests in the GP's office]
    H Jablonowski
    Klinikum Salzgitter GmbH
    MMW Fortschr Med 148:48-51. 2006
    ..Further function tests for the detection of pancreatic insufficiency, such as the determination of fecal pancreatic elastase, are also available...
  26. ncbi Laparoscopic fundoplication and gastrostomy
    Daniel J Ostlie
    Department of Surgery, Children s Mercy Hospital, Kansas City, MO 64108, USA
    Semin Pediatr Surg 11:196-204. 2002
    ..Also, the laparoscopic Nissen fundoplication technique currently utilized at Children's Mercy Hospital is described...
  27. ncbi The gastro-oesophageal common cavity revisited
    M C Aanen
    Gastrointestinal Research Unit, University Medical Center, Utrecht, The Netherlands
    Neurogastroenterol Motil 18:1056-61. 2006
    ..The common cavity is a specific but not a sensitive marker of gastro-oesophageal reflux. Furthermore, common cavities are not specific for a particular type of reflux...
  28. ncbi Gastro-oesophageal reflux in obese subjects: influence of overweight, weight loss and chronic gastric balloon distension
    E M H Mathus-Vliegen
    Dept of Gastroenterology and Hepatology, Academic Medical Centre, University of Amsterdam, The Netherlands
    Scand J Gastroenterol 37:1246-52. 2002
    ..The purpose of the study was to investigate the prevalence of gastro-oesophageal reflux in untreated obese subjects and to study the consequences of weight loss with or without intragastric balloon treatment...
  29. ncbi The use of proton pump inhibitors as a diagnostic test for gastroesophageal reflux disease
    Mattijs E Numans
    Arch Intern Med 166:247-8; author reply 248-9. 2006
  30. ncbi Five-year comprehensive outcomes evaluation in 181 patients after laparoscopic Nissen fundoplication
    Mehran Anvari
    Centre for Minimal Access Surgery and Department of Medicine, St Joseph s Hospital, McMaster University, Hamilton, Ontario, Canada
    J Am Coll Surg 196:51-7; discussion 57-8; author reply 58-9. 2003
    ..We conducted an objective followup of 181 patients after laparoscopic Nissen fundoplication during a 5-year period after surgery...
  31. ncbi Centre-specific multichannel electrogastrographic testing utilizing wavelet-based decomposition
    I V Tchervensky
    Department of Electrical and Computer Engineering, University of Calgary, Calgary, Alberta T2N 1N4, Canada
    Physiol Meas 27:569-84. 2006
    ..0%. The utilization of a wavelet-based decomposition technique to process multichannel EGG signals can be a very effective method for enhancing the clinical utility of EGG, provided it is specifically developed for a given testing centre...
  32. ncbi Use of healthcare resources among medically and surgically treated patients with gastroesophageal reflux disease: a population-based study
    M D Holzman
    Department of Surgery, Vanderbilt University and Nashville Veteran Affairs Medical Center, TN, USA
    J Am Coll Surg 192:17-24. 2001
    ....
  33. ncbi Dietary restrictions during ambulatory monitoring of duodenogastroesophageal reflux
    Jan Tack
    Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
    Dig Dis Sci 48:1213-20. 2003
    ..Thus, ambulatory Bilitec monitoring requires the use of liquid meals, as the use of solid meals is associated with too many meal artifacts and a poorer correlation with acid reflux and severity of endoscopic lesions...
  34. ncbi Foregut abnormalities
    Bindi Naik-Mathuria
    Division of Pediatric Surgery, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Texas Children s Hospital, 6621 Fannin CC 650 00, Houston, TX 77030 2399, USA
    Surg Clin North Am 86:261-84, viii. 2006
  35. ncbi [Relationship between globus sensation and esophageal clearance abnormalities in an elderly group]
    Mutsumi Sugiura
    Department of Otorhinolaryngology, Nihon University School of Medicine, Tokyo
    Nihon Jibiinkoka Gakkai Kaiho 109:524-9. 2006
    ..Videopharyngoesophageal examination in the prone position may be an easy and valuable method for evaluating the function of esophageal clearance...
  36. ncbi Ear, nose, and throat manifestations of gastroesophageal reflux disease. Complaints can be telltale signs
    Larry K Burton
    Mayo Clinic, Rochester, Minnesota, USA
    Postgrad Med 117:39-45. 2005
    ....
  37. ncbi Gastro-oesophageal reflux disease: oesophageal impedance versus pH monitoring
    Yvan Vandenplas
    Universitair Ziekenhuis Brussel, Brussels, Belgium
    Acta Paediatr 96:956-62. 2007
    ..The high cost of the material and the investment in time necessary for interpretation of the recording, remains a handicap. It is mandatory, despite ethical difficulties, to obtain normal ranges for intraluminal impedance monitoring...
  38. ncbi Diagnosing gastroesophageal reflux disease
    L A Szarka
    Division of Gastroenterology and Hepatology and Internal Medicine, Mayo Clinic, Rochester, Minn. 55905, USA
    Mayo Clin Proc 76:97-101. 2001
    ..Optimal use of currently available tests for GERD may allow for more efficient diagnosis and better characterization of the pathological manifestations associated with GERD...
  39. ncbi Noncardiac chest pain: evaluation and treatment
    Guy D Eslick
    Department of Medicine, University of Sydney, Nepean Hospital, Level 5, South Block, PO Box 63, Penrith, New South Wales 2751, Australia
    Gastroenterol Clin North Am 32:531-52. 2003
    ..Finally, trials of management strategies to deal with this problem are required urgently, because the earlier discharge of patients with NCCP may exacerbate the problem. Fig. 2 provides a flow chart for diagnosis and treatment of NCCP...
  40. ncbi Bolus transit patterns in healthy subjects: a study using simultaneous impedance monitoring, videoesophagram, and esophageal manometry
    Hala Imam
    Department of Gastroenterology, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, Ohio 44195, USA
    Am J Physiol Gastrointest Liver Physiol 288:G1000-6. 2005
    ..6 s until cleared into the stomach. We conclude that impedance monitoring is a valid transit test and describe bolus transit patterns in normal subjects for comparison with patients with esophageal motility disorders...
  41. ncbi Are 10 wet swallows an appropriate sample of esophageal motility? Yes and no
    Sajid Jalil
    Division of Gastroenterology and Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
    J Clin Gastroenterol 38:30-4. 2004
    ..Given this relative small number of swallows concerns have been raised whether the abnormal findings based on 10 wet swallows would persist with another set of 10 wet swallows...
  42. ncbi [Diagnostic procedures in esophageal diseases]
    L Degen
    , Kantonsspital, Basel
    Ther Umsch 58:125-7. 2001
    ..Radiographic tests are indicated for special indications only. Finally, the role of functional tests (manometry, 24-hour pH-metry) and their indications are discussed...
  43. ncbi Dissecting oesophageal sensori-motor functions: the fourth domain
    Adil E Bharucha
    Clinical Enteric Neuroscience Translational and Epidemiological Research C E N T E R Program, Mayo Clinic College of Medicine, Rochester, MN, USA
    Neurogastroenterol Motil 18:169-71. 2006
  44. doi Guiding manometry probes into the human small bowel without X-ray: validation of a new technique
    J V Schönfeld
    Klinik fur Innere Medizin, Marienkrankenhaus, Bergisch Gladbach, Germany
    Digestion 77:118-21. 2008
    ..This is usually controlled by fluoroscopy, but a method that allows to place the tubes without X-rays is obviously desirable...
  45. ncbi Accuracy of liver stiffness measurement for the diagnosis of cirrhosis in patients with chronic liver diseases
    Nathalie Ganne-Carrie
    Hépato Gastroentérologie, Hopital Jean Verdier, Bondy, France UPRES EA3409, Universite Paris 13, Bobigny, France
    Hepatology 44:1511-7. 2006
    ..6 kPa. False-negatives are mainly attributable to inactive or macronodular cirrhosis...
  46. ncbi Rectal hyposensitivity: prevalence and clinical impact in patients with intractable constipation and fecal incontinence
    Marc A Gladman
    Academic Department of Surgery and Gastrointestinal Physiology Unit, Barts and The London, Queen Mary s School of Medicine and Dentistry, United Kingdom
    Dis Colon Rectum 46:238-46. 2003
    ..The purpose of this study was to determine the prevalence of rectal hyposensitivity and whether the finding of such an abnormality was associated with any clinical impact...
  47. ncbi [Development and applications of a gastrointestinal monitoring microsystem based on the smart capsule]
    Wen qiang Zhang
    School of Electronics and Electrical Engineering, Shanghai Jiaotong University, Shanghai
    Zhongguo Yi Liao Qi Xie Za Zhi 30:366-8. 2006
    ..The average of HAPCs occurred in patients is significantly lower than in volunteers (12.4 +/- 3.3 vs. 18.5 +/- 3.7 p = 0.013). The system provides a useful tool for STC diagnosis and treatments of patients...
  48. ncbi How do I interpret a positive diagnostic test?
    Jerry D Gardner
    Gastrointest Endosc 66:891-3. 2007
  49. ncbi Significant liver damage in patients with bleeding disorders and chronic hepatitis C: non-invasive assessment of liver fibrosis using transient elastography
    D Posthouwer
    Van Creveldkliniek, University Medical Utrecht, Utrecht, The Netherlands
    J Thromb Haemost 5:25-30. 2007
    ..Liver biopsies are generally not performed in these patients because of increased bleeding risk and high costs. We therefore assessed liver fibrosis and cirrhosis non-invasively using liver stiffness measurement (LSM)...
  50. pmc Adult constipation: a review and clinical guide
    T Q Jacobs
    Case Western Reserve University School of Medicine, Cleveland, OH 44106 4966, USA
    J Natl Med Assoc 93:22-30. 2001
    ..Testing methods and their value in the evaluation of chronic idiopathic constipation are discussed. Finally, although the focus of this article is the evaluation of constipation, a section on the treatment of constipation is included...
  51. ncbi Re-evaluation of the penicillamine challenge test in the diagnosis of Wilson's disease in children
    Thomas Muller
    Department of Pediatrics II, Medical University of Innsbruck, Innsbruck, Austria
    J Hepatol 47:270-6. 2007
    ..2% and sensitivity of 88.2% in diagnosing Wilson's disease (WD). We have re-evaluated this test. Ninety-eight subjects were studied at presentation...
  52. doi Gastrointestinal stromal tumors: report of an audit and review of the literature
    Guido Biasco
    Institute of Hematology and Medical Oncology L A Seragnoli, Policlinico Sant Orsola Malpighi, University of Bologna, Bologna, Italy
    Eur J Cancer Prev 18:106-16. 2009
    ....
  53. ncbi How initial tumor stage affects rectal cancer patient follow-up
    Kenichi Ode
    Education Centre, Royal Lancaster Infirmary, Lancaster LA1 4RR, UK
    Oncol Rep 21:1511-7. 2009
    ..This suggests that a controlled trial comparing high-intensity versus low-intensity follow-up testing could be carried out without stratification by TNM stage...
  54. ncbi [Helicobacter pylori 25 years after (1983 -2008): epidemiology, microbiology, pathogenics, diagnostics and treatment]
    Alberto Ramírez Ramos
    Profesor Emérito e Investigador de la Universidad Peruana Cayetano Heredia
    Rev Gastroenterol Peru 29:158-70. 2009
    ..MICROBIOLOGY: Three strains predominant in Spanish, Asiatic and people from India have been identified. DNA has 1.65 million bases. Different factors of virulence, enzymes and toxins have also been described...
  55. doi Wireless capsule endoscopy in Italy: adding context-specific data to the review of the evidence from literature
    Alessandra Lo Scalzo
    Innovation and Development Department HTA Unit, Agenzia Nazionale per i Servizi Sanitari Regionali Agenas, Via Puglie 23, Rome, 00187, Italy
    Int J Technol Assess Health Care 25:297-304. 2009
    ....
  56. doi Current staging and diagnosis of gastroesophageal varices
    Nayantara Coelho-Prabhu
    Mayo Clinic Rochester, MN 55905, USA
    Clin Liver Dis 14:195-208. 2010
    ..Cirrhosis is the most common cause of portal hypertension in the western world and results from increased resistance to blood flow at the hepatic sinusoidal level...
  57. doi [Childhood periodic syndromes]
    J C Cuvellier
    Service de Neuropediatrie, Hopital Roger Salengro, Clinique de Pediatrie, Rue Emile Laine, Lille Cedex, France
    Rev Neurol (Paris) 166:574-83. 2010
    ..g., cyproheptadine in children 5 years or younger and amitriptyline for those older than 5 years), and acute therapy (e.g., triptans, as abortive therapy, and 10% glucose and ondansetron for those requiring intravenous hydration)...
  58. doi Asian perspectives in the management of inflammatory bowel disease: findings from a recent survey
    Joseph J Y Sung
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong
    J Gastroenterol Hepatol 25:183-93. 2010
    ..The present study aims to investigate the number of existing and new cases of IBD and to understand the current practice of diagnosis and treatment of IBD in different Asian countries...
  59. ncbi Gastroesophageal reflux
    Sonia Michail
    Wright State University, Boonshoft School of Medicine, Dayton Children s Medical Center, Dayton, Ohio, USA
    Pediatr Rev 28:101-10. 2007
  60. doi A meal test improves the specificity of chromogranin A as a marker of neuroendocrine neoplasia
    Constantin S Jianu
    Department of Gastroenterology and Hepatology, St Olav s Hospital, Olav Kyrres gt 17, 7006, Trondheim, Norway
    Tumour Biol 31:373-80. 2010
    ..Concomitant gastrin determination may help to discriminate between nongastric NETs and CAG. Intravenous octreotide rapidly reduces serum CgA...
  61. ncbi The use of transient elastometry for assessing liver fibrosis in patients with HIV and hepatitis C virus coinfection
    Salvador Vergara
    Clinical Unit of Infectious Diseases, Department of Internal Medicine, Hospital Universitario de Valme, Seville, Spain
    Clin Infect Dis 45:969-74. 2007
    ..The purpose of this study was to validate reported cutoff values of TE that discriminate significant liver fibrosis and cirrhosis in HIV-HCV-coinfected subjects...
  62. ncbi Hematochezia in the young patient: a review of health-seeking behavior, physician attitudes, and controversies in management
    Rashid Khan
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza, BCM Mailstop 285, Houston, TX 77030, USA
    Dig Dis Sci 55:233-9. 2010
    ..In this review, the value of clinical symptoms and the underlying risk of CRC in guiding this clinical decision will be discussed...
  63. doi Herniography: a reliable investigation avoiding needless groin exploration--a retrospective study
    M I Hachem
    Department of Surgery, Eastbourne District General Hospital, Eastbourne, UK
    Hernia 13:57-60. 2009
    ..Herniography has been shown to be useful in the detection of occult groin hernias in patients with a history of groin pain. We performed a retrospective review to assess our experience of this investigation...
  64. pmc Effects of anatomical position on esophageal transit time: a biomagnetic diagnostic technique
    Teodoro Córdova-Fraga
    Instituto de Fisica, Universidad de Guanajuato, Lomas del Campestre, Leon 37150, Gto, Mexico
    World J Gastroenterol 14:5707-11. 2008
    ..To study the esophageal transit time (ETT) and compare its mean value among three anatomical inclinations of the body; and to analyze the correlation of ETT to body mass index (BMI)...
  65. doi Enteroaggregative Escherichia coli infection
    Jose Flores
    Division of Infectious Diseases, The University of Texas Medical School at Houston, Texas, USA
    Curr Opin Gastroenterol 25:8-11. 2009
    ..To review studies that improve the current knowledge on the epidemiology, virulence factors, detection, and chronic complications of enteroaggregative Escherichia coli (EAEC) infection...
  66. pmc Gastroparesis: current diagnostic challenges and management considerations
    Shamaila Waseem
    Department of Pediatric Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, Florida 32610, USA
    World J Gastroenterol 15:25-37. 2009
    ..In this comprehensive review, we discuss gastroparesis with emphasis on the latest developments; from the perspective of the practicing clinician...
  67. doi Multi-sensor radiotelemetry system for intestinal motility measurement
    H Biao
    No 820 Lab, Department of Instrument, Shanghai Jiaotong University, Shanghai, PR China
    J Med Eng Technol 33:66-71. 2009
    ..Clinical experiments prove that the radiotelemetry system is non-invasive and reliable. Moreover it is found that the radiotelemetry system is an effective method to study intestine motility characteristics...
  68. pmc Axial force measurement for esophageal function testing
    Flemming H Gravesen
    Mech Sense, Department of Gastroenterology, Aalborg Hospital, Aalborg, Denmark
    World J Gastroenterol 15:139-43. 2009
    ..Using axial force in combination with manometry provides a more complete picture of esophageal motility, and the current paper outlines the advantages of using this method...
  69. ncbi Bedside assessment of swallowing in stroke: water tests are not enough
    Charles Henrique Dias Marques
    Department of Internal Medicine, Faculdade de Medicina da Universidade Federal do Rio de Janeiro, Brazil
    Top Stroke Rehabil 15:378-83. 2008
    ..The clinical functional evaluation is the usual method for dysphagia screening in patients with acute stroke. This study compared two methods of evaluation--with liquid and semisolid viscosities...
  70. doi Reproducibility and symptomatic predictors of a slow nutrient drinking test in health and in functional dyspepsia
    S Kindt
    Center for Gastroenterological Research, University of Leuven, K U Leuven, Belgium
    Neurogastroenterol Motil 20:320-9. 2008
    ..The slow nutrient drinking test confirms its possible role as an attractive non-invasive and reproducible tool for the diagnosis of impaired accommodation and for the assessment of treatment responsiveness...
  71. doi The evolution of oesophageal function testing and its clinical applications in the management of patients with oesophageal disorders
    P M Fisichella
    Loyola University Medical Center, Department of Surgery, Stritch School of Medicine, 2160 South First Avenue Room 3226, Maywood, IL 60153, United States
    Dig Liver Dis 41:626-9. 2009
    ....
  72. ncbi Analysis of new diagnostic methods in suspicious lesions of the oral mucosa
    Anna Trullenque-Eriksson
    Dentistry graduate, Official Master in Dentistry Science, Universidad Complutense de Madrid, Spain
    Med Oral Patol Oral Cir Bucal 14:E210-6. 2009
    ....
  73. ncbi Microballoon occlusion test to predict colonic ischemia after transcatheter embolization of a ruptured aneurysm of the middle colic artery
    Tsuyoshi Tajima
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, 812 8582, Japan
    Cardiovasc Intervent Radiol 31:828-32. 2008
    ..No colonic ischemia or aneurysm rupture occurred after embolization...
  74. ncbi Drinking tests in functional dyspepsia: what do they really measure?
    K Mimidis
    First Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis, Greece
    Neurogastroenterol Motil 19:947-50. 2007
  75. ncbi A systematic review of diagnostic tests for small intestinal bacterial overgrowth
    Reza Khoshini
    Division of Gastroenterology, Harbor UCLA Medical Center, Torrance, CA, USA
    Dig Dis Sci 53:1443-54. 2008
    ..In this systematic review, the validity of culture and other diagnostic testing for SIBO is evaluated...
  76. doi Manometric, sensorimotor, and neurophysiologic evaluation of anorectal function
    S Mark Scott
    GI Physiology Unit and Neurogastroenterology Group Centre for Academic Surgery, Institute of Cell and Molecular Science, Barts, London, UK
    Gastroenterol Clin North Am 37:511-38, vii. 2008
    ..The techniques, limitations, measurements, and clinical use of manometric, sensorimotor, and neurophysiologic tests of anorectal function are presented...
  77. ncbi Clinical usefulness of gastric-juice analysis in 2007: the stone that the builders rejected has become the cornerstone
    Antonio Tucci
    Gastrointestinal Unit of Castel S Pietro Terme Hospital, University of Bologna, AUSL of Imola, Italy
    Gastrointest Endosc 66:881-90. 2007
    ..Gastric juice is usually discarded during upper-GI endoscopy...
  78. ncbi [Imaging methods in liver diseases]
    Jakab Zsuzsa
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 145:1691-8. 2004
    ..She describes the possibilities, performance and disadvantages of the imaging procedures. She makes a recommendation for a generally applicable optimal investigative sequence...
  79. ncbi Lack of association between esophageal acid sensitivity detected by prolonged pH monitoring and Bernstein testing
    Barbara Jung
    University of California, San Diego, California, USA
    Am J Gastroenterol 99:410-5. 2004
    ..We tested the relationship between heartburn and acid in the esophagus by determining the SI and Bernstein test results in the same individual...
  80. ncbi Estimating medical costs of gastroenterological diseases
    Li Fang Chou
    Department of Public Finance, National Chengchi University, Taipei, Taiwan, China
    World J Gastroenterol 10:273-8. 2004
    ..To estimate the direct medical costs of gastroenterological diseases within the universal health insurance program among the population of local residents in Taiwan...
  81. ncbi Heller's esophagomyotomy with or without a 360 degrees floppy Nissen fundoplication for achalasia. Long-term results from a prospective randomized study
    D Falkenback
    Department of Surgery, Business Area Elective Surgery, Helsingborg Hospital Inc, Helsingborg, Sweden
    Dis Esophagus 16:284-90. 2003
    ..The addition of a 360 degrees fundoplication eliminates reflux without adding dysphagia in the majority of patients and can be recommended for most patients with uncomplicated achalasia...
  82. ncbi Diagnostic tests for gastroesophageal reflux disease
    Joel E Richter
    Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Ohio 44195, USA
    Am J Med Sci 326:300-8. 2003
    ..By using the available tests judiciously, one can increase the opportunity of making a correct diagnosis of GERD and simultaneously limit the potential inconveniences or cost to the patient...
  83. ncbi Assessment of intestinal permeability and orocecal transit time in patients with systemic sclerosis: analysis of relationships with epidemiologic and clinical parameters
    Luigi Caserta
    Gastroenterology Unit, Magrassi Lanzara Department of Clinical and Experimental Internal Medicine, Second University of Naples, Naples, Italy
    Rheumatol Int 23:226-30. 2003
    ..The aim of this study was to assess intestinal permeability (IP) in patients with systemic sclerosis (SSc) and to relate the results with general disease activity and gastrointestinal involvement...
  84. ncbi [Gastroesophageal reflux disease]
    A Arin
    Servicio de Digestivo, Hospital de Navarra, 31008 Pamplona, Spain
    An Sist Sanit Navar 26:251-68. 2003
    ..We describe typical and atypical or extra esophageal clinical manifestations, while bringing up to date the diagnostic methodology. Finally, we review the present state of treatment in its pharmacological, endoscopic and surgical facets..
  85. ncbi Minimally invasive management of epiphrenic esophageal diverticula
    Brent D Matthews
    Department of General Surgery, Carolina s Laparoscopic and Advanced Surgery Program, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
    Am Surg 69:465-70; discussion 470. 2003
    ..Long-term outcomes should be monitored during the evolution of these novel minimally invasive techniques to ensure outcomes comparable to those of a transthoracic open approach...
  86. ncbi Irritable bowel syndrome: epidemiology and diagnosis
    Yishai Ron
    Department of Gastroenterology, Wolfson Medical Center, Holon, Israel
    Isr Med Assoc J 5:201-2. 2003
  87. ncbi [Electrogastroenterography in diagnosis of pyloroduodenal ulcers]
    R Sh Shaĭmardanov
    Klin Med (Mosk) 81:45-7. 2003
    ..The proposed method can be applied both for diagnosis of the motor-evacuatory disorders and control of therapy in patients with uncomplicated PDU, adequacy of preooperative preparation in complication of ulcer with pyloristenosis...
  88. ncbi Diagnosis of symptomatic gastroesophageal reflux disease
    Peter J Kahrilas
    Department of Medicine, Section of Gastroenterology, Northwestern University Feinberg School of Medicine, Suite 1400, 676 N St Clair Street, Chicago, IL 60611 2927, USA
    Am J Gastroenterol 98:S15-23. 2003
    ..It has been shown effective in about 75% of patients, and offers a simple approach to managing the difficult-to-diagnose patient even while further diagnostic procedures are carried out...
  89. ncbi Autonomic nerve dysfunction in pathologically obese patients
    E Surrenti
    Gastroenterology Unit, Department of Clinical Physiopathology, University of Florence, Azienda Ospedaliera Careggi, Florence, Italy
    Dig Liver Dis 34:768-74. 2002
    ..Obese patients frequently present clinical symptoms related to gastrointestinal motility alterations and autonomic nervous system dysfunction...
  90. ncbi Studies on the relationship between esophageal acid exposure, mucosal lesions and heartburn using an acid exposure sensor
    G Vantrappen
    Center for Gastroenterological Research and Dept of Pathology, University Hospital Gasthuisberg and Interuniversity Micro Electronics Centre, University of Leuven, Leuven, Belgium
    Scand J Gastroenterol 37:1253-8. 2002
    ..The aim was to determine whether SR correlates with the severity of acid-induced esophageal mucosal lesions and acid-induced heartburn...
  91. ncbi Overview and diagnosis of malabsorption syndrome
    James J Farrell
    Division of Digestive Diseases, UCLA School of Medicine, UCLA Center for the Health Science, Los Angeles, CA 90095, USA
    Semin Gastrointest Dis 13:182-90. 2002
    ..This review discusses the etiology and pathophysiology of malabsorption. A diagnostic approach to malabsorption is proposed. Other articles review specific disorders such as celiac disease, bacterial overgrowth, and chronic pancreatitis...
  92. ncbi The end of diagnosis: when to stop testing
    Amnon Sonnenberg
    Gastroenterology Section, Department of Veterans Affairs Medical Center, Albuquerque, NM 87108, USA
    Am J Gastroenterol 97:2494-8. 2002
    ....
  93. ncbi Whither the Bernstein test?
    Benson T Massey
    Am J Gastroenterol 99:416-8. 2004
  94. pmc Bringing science to the art of diagnosis
    P Moayyedi
    Gastroenterology Division, McMaster University HSC 4W8, Hamilton, Ontario, Canada L8N 3Z5
    Gut 53:627-8. 2004
  95. ncbi Clinical application of polymerase chain reaction to diagnose Clostridium difficile in hospitalized patients with diarrhea
    Michael S Morelli
    Division of Digestive Diseases, University of Cincinnati, Ohio, USA
    Clin Gastroenterol Hepatol 2:669-74. 2004
    ..We sought to show the usefulness and potential cost effectiveness of polymerase chain reaction (PCR) amplification of toxin B gene for diagnosis of C. difficile-induced diarrhea...
  96. ncbi Evaluation of the abdomen in the critically ill patient: opening the black box
    Marie Crandall
    Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Curr Opin Crit Care 12:333-9. 2006
    ..Evaluation of the abdomen in critically ill patients can be challenging. This article reviews the available data and proposes evidence-based guidelines for evaluation of the abdomen in the critically ill patient...
  97. ncbi A review of digestible microsystems for gastrointestinal tract diagnostic applications
    A Arshak
    Physics Department, University of Limerick, Ireland
    Crit Rev Biomed Eng 34:163-86. 2006
    ..These systems have the potential to improve diagnostic yield and, in the future, treatment of disease using these capsules should become a reality...
  98. ncbi An evidence-based, Latin-American consensus on gastro-oesophageal reflux disease
    Henry Cohen
    Department of Gastroenterology, Uruguayan Medical School, Montevideo, Uruguay
    Eur J Gastroenterol Hepatol 18:349-68. 2006
    ..The methodology, results and recommendations of the consensus are described in detail...
  99. ncbi [Useful clinical tests for early diagnosis of liver, biliary, and pancreatic diseases]
    Masahiko Sunaga
    Nihon Naika Gakkai Zasshi 94:2514-22. 2005
  100. ncbi [Useful clinical laboratory tests for early diagnosis of gastrointestinal diseases]
    Yumiko Ishino
    Nihon Naika Gakkai Zasshi 94:2508-13. 2005
  101. pmc Role of rapid urease test and histopathology in the diagnosis of Helicobacter pylori infection in a developing country
    Javed Yakoob
    Department of Gastroenterology and Pathology, Aga Khan University Hospital, Karachi, Pakistan
    BMC Gastroenterol 5:38. 2005
    ..The aim of this study was to determine the effect of commonly self-prescribed proton pump inhibitors (PPI) on the results of rapid urease test and histology for the diagnosis of H. pylori infection...

Research Grants19

  1. ANORECTAL MANIFESTATIONS OF FEMALE PELVIC FLOOR DISORDER
    Adil Bharucha; Fiscal Year: 2000
    ..abstract_text> ..
  2. Epidemiology and Mechanisms of Fecal Incontinence
    Adil Bharucha; Fiscal Year: 2005
    ..abstract_text> ..
  3. Epidemiology and Mechanisms of Fecal Incontinence
    Adil Bharucha; Fiscal Year: 2004
    ..abstract_text> ..
  4. Epidemiology and Mechanisms of Fecal Incontinence
    Adil Bharucha; Fiscal Year: 2003
    ..abstract_text> ..
  5. Pathophysiology of Anorectal Disorders
    Adil Bharucha; Fiscal Year: 2009
    ..This proposal will enhance our understanding of the mechanisms and assess novel approaches to manage FI. ..
  6. ANORECTAL MANIFESTATIONS OF FEMALE PELVIC FLOOR DISORDER
    Adil Bharucha; Fiscal Year: 2002
    ..abstract_text> ..
  7. Epidemiology and Mechanisms of Fecal Incontinence
    Adil Bharucha; Fiscal Year: 2002
    ..abstract_text> ..
  8. Pathophysiology of Anorectal Disorders
    Adil E Bharucha; Fiscal Year: 2010
    ..This proposal will enhance our understanding of the mechanisms and assess novel approaches to manage FI. ..
  9. ANORECTAL MANIFESTATIONS OF FEMALE PELVIC FLOOR DISORDER
    Adil Bharucha; Fiscal Year: 2001
    ..abstract_text> ..
  10. Epidemiology and Mechanisms of Fecal Incontinence
    Adil Bharucha; Fiscal Year: 2001
    ..abstract_text> ..
  11. Pathophysiology of Anorectal Disorders
    Adil Bharucha; Fiscal Year: 2008
    ..This proposal will enhance our understanding of the mechanisms and assess novel approaches to manage FI. ..
  12. Novel Treatment Strategies for Constipation and Role of Brain-Gut axis
    Satish Rao; Fiscal Year: 2009
    ..These studies aim to define the mechanisms of, and evaluate new therapies for dyssynergia, rectal hyposensitivity and rectal hypersensitivity, and could significantly impact constipation treatments. ..
  13. Novel Treatment Strategies for Constipation and Role of Brain-Gut axis
    Satish Rao; Fiscal Year: 2008
    ..These studies aim to define the mechanisms of, and evaluate new therapies for dyssynergia, rectal hyposensitivity and rectal hypersensitivity, and could significantly impact constipation treatments. ..
  14. Novel Treatment Strategies for Constipation and Role of Brain-Gut axis
    Satish Rao; Fiscal Year: 2007
    ..These studies aim to define the mechanisms of, and evaluate new therapies for dyssynergia, rectal hyposensitivity and rectal hypersensitivity, and could significantly impact constipation treatments. ..
  15. NEUROMUSCULAR CONDITION THERAPY-DYSSYNERGIC DEFECATION
    Satish Rao; Fiscal Year: 2004
    ..abstract_text> ..
  16. NEUROMUSCULAR CONDITION THERAPY-DYSSYNERGIC DEFECATION
    Satish Rao; Fiscal Year: 2003
    ..abstract_text> ..
  17. NEUROMUSCULAR CONDITION THERAPY-DYSSYNERGIC DEFECATION
    Satish Rao; Fiscal Year: 2002
    ..abstract_text> ..
  18. NEUROMUSCULAR CONDITION THERAPY-DYSSYNERGIC DEFECATION
    Satish Rao; Fiscal Year: 2001
    ..abstract_text> ..
  19. Novel Treatment Strategies for Constipation and Role of Brain-Gut axis
    SATISH SC RAO; Fiscal Year: 2010
    ..These studies aim to define the mechanisms of, and evaluate new therapies for dyssynergia, rectal hyposensitivity and rectal hypersensitivity, and could significantly impact constipation treatments. ..