blood flow velocity

Summary

Summary: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.

Top Publications

  1. ncbi Wave propagation in a model of the arterial circulation
    J J Wang
    Physiological Flow Studies Group, Department of Bioengineering, Imperial College of Science, Technology and Medicine, London SW7 2AZ, UK
    J Biomech 37:457-70. 2004
  2. ncbi Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Hypertension 39:10-5. 2002
  3. pmc Interaction between alk1 and blood flow in the development of arteriovenous malformations
    Paola Corti
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Development 138:1573-82. 2011
  4. ncbi A general kinetic model for quantitative perfusion imaging with arterial spin labeling
    R B Buxton
    Department of Radiology, University of San Diego, California, USA
    Magn Reson Med 40:383-96. 1998
  5. doi The complex interaction between ocular perfusion pressure and ocular blood flow - relevance for glaucoma
    Doreen Schmidl
    Department of Clinical Pharmacology, Medical University of Vienna, Austria
    Exp Eye Res 93:141-55. 2011
  6. pmc Flow measurement by cardiovascular magnetic resonance: a multi-centre multi-vendor study of background phase offset errors that can compromise the accuracy of derived regurgitant or shunt flow measurements
    Peter D Gatehouse
    CMR Unit, Royal Brompton Hospital, London, UK
    J Cardiovasc Magn Reson 12:5. 2010
  7. ncbi Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival
    Stephen Trzeciak
    Division of Cardiovascular Disease and Critical Care Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ 08103, USA
    Ann Emerg Med 49:88-98, 98.e1-2. 2007
  8. doi Magnetic resonance-derived 3-dimensional blood flow patterns in the main pulmonary artery as a marker of pulmonary hypertension and a measure of elevated mean pulmonary arterial pressure
    Gert Reiter
    Siemens Medical Solutions, Graz, Austria
    Circ Cardiovasc Imaging 1:23-30. 2008
  9. ncbi Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress
    Caroline Cheng
    Department of Cardiology, Thoraxcenter, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Circulation 113:2744-53. 2006
  10. ncbi Arterial wave reflections and survival in end-stage renal failure
    G M London
    Service d Hemodialyse, Hôpital F H Manhès, Fleury Merogis, Ste Genevieve des Bois, France
    Hypertension 38:434-8. 2001

Detail Information

Publications274 found, 100 shown here

  1. ncbi Wave propagation in a model of the arterial circulation
    J J Wang
    Physiological Flow Studies Group, Department of Bioengineering, Imperial College of Science, Technology and Medicine, London SW7 2AZ, UK
    J Biomech 37:457-70. 2004
    ..We conclude from these calculations that the complex pattern of wave propagation in the large arteries may be the most important determinant of arterial haemodynamics...
  2. ncbi Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Hypertension 39:10-5. 2002
    ..This study provides the first direct evidence in a longitudinal study that aortic stiffness is an independent predictor of primary coronary events in patients with essential hypertension...
  3. pmc Interaction between alk1 and blood flow in the development of arteriovenous malformations
    Paola Corti
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Development 138:1573-82. 2011
    ....
  4. ncbi A general kinetic model for quantitative perfusion imaging with arterial spin labeling
    R B Buxton
    Department of Radiology, University of San Diego, California, USA
    Magn Reson Med 40:383-96. 1998
    ..In preliminary experiments with a human subject, the model provided a good description of pulsed ASL data during a simple sensorimotor activation task...
  5. doi The complex interaction between ocular perfusion pressure and ocular blood flow - relevance for glaucoma
    Doreen Schmidl
    Department of Clinical Pharmacology, Medical University of Vienna, Austria
    Exp Eye Res 93:141-55. 2011
    ..Indeed there is data indicating that reduction of IOP by pharmacological intervention improves optic nerve head blood flow regulation independently of an ocular vasodilator effect...
  6. pmc Flow measurement by cardiovascular magnetic resonance: a multi-centre multi-vendor study of background phase offset errors that can compromise the accuracy of derived regurgitant or shunt flow measurements
    Peter D Gatehouse
    CMR Unit, Royal Brompton Hospital, London, UK
    J Cardiovasc Magn Reson 12:5. 2010
    ..We studied the severity of uncorrected velocity offset errors across sites and CMR systems...
  7. ncbi Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival
    Stephen Trzeciak
    Division of Cardiovascular Disease and Critical Care Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ 08103, USA
    Ann Emerg Med 49:88-98, 98.e1-2. 2007
    ....
  8. doi Magnetic resonance-derived 3-dimensional blood flow patterns in the main pulmonary artery as a marker of pulmonary hypertension and a measure of elevated mean pulmonary arterial pressure
    Gert Reiter
    Siemens Medical Solutions, Graz, Austria
    Circ Cardiovasc Imaging 1:23-30. 2008
    ..Such pathological altered pressures in the pulmonary vascular system should lead to changes in blood flow patterns in the main pulmonary artery...
  9. ncbi Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress
    Caroline Cheng
    Department of Cardiology, Thoraxcenter, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Circulation 113:2744-53. 2006
    ..However, the effect of shear stress on plaque vulnerability is unknown because the lack of an appropriate in vivo model precludes cause-effect studies...
  10. ncbi Arterial wave reflections and survival in end-stage renal failure
    G M London
    Service d Hemodialyse, Hôpital F H Manhès, Fleury Merogis, Ste Genevieve des Bois, France
    Hypertension 38:434-8. 2001
    ..16 to 1.90; P<0.0001) for CV mortality. These results provide the first direct evidence that in ESRF patients increased effect of arterial wave reflections is an independent predictor of all-cause and CV mortality...
  11. pmc Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in vascular networks
    Walid S Kamoun
    Edwin L Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Nat Methods 7:655-60. 2010
    ..Furthermore, we show that subpopulations of vessels, classified by functional parameters, exist in and around a tumor and in normal brain tissue...
  12. ncbi Respiratory changes in aortic blood velocity as an indicator of fluid responsiveness in ventilated patients with septic shock
    M Feissel
    , Centre Hospitalier, Belfort, France
    Chest 119:867-73. 2001
    ....
  13. pmc Comprehensive 4D velocity mapping of the heart and great vessels by cardiovascular magnetic resonance
    Michael Markl
    Department of Radiology, Medical Physics, University Hospital Freiburg, Germany
    J Cardiovasc Magn Reson 13:7. 2011
    ..In this article, methods used for the acquisition, visualization, and quantification of such datasets are reviewed and illustrated...
  14. ncbi Efficient pipeline for image-based patient-specific analysis of cerebral aneurysm hemodynamics: technique and sensitivity
    Juan R Cebral
    School of Computational Sciences, George Mason University, 4400 University Drive, MSN 4C7, Fairfax, VA 22030, USA
    IEEE Trans Med Imaging 24:457-67. 2005
    ..We conclude that with the proposed modeling pipeline clinical studies involving large numbers cerebral aneurysms are feasible...
  15. ncbi Brachial-ankle pulse wave velocity: an index of central arterial stiffness?
    J Sugawara
    Institute for Human Science and Bioengineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    J Hum Hypertens 19:401-6. 2005
    ..These results suggest that baPWV may provide qualitatively similar information to those derived from central arterial stiffness although some portions of baPWV may be determined by peripheral arterial stiffness...
  16. ncbi Experimental validation of a time-domain-based wave propagation model of blood flow in viscoelastic vessels
    David Bessems
    Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech 41:284-91. 2008
    ....
  17. ncbi Applications of phase-contrast flow and velocity imaging in cardiovascular MRI
    Peter D Gatehouse
    Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, UK
    Eur Radiol 15:2172-84. 2005
    ..The review includes phase-contrast applications in cardiac function, heart valves, congenital heart diseases, major blood vessels, coronary arteries and myocardial wall velocity...
  18. doi Dissociation of aortic pulse wave velocity with risk factors for cardiovascular disease other than hypertension: a systematic review
    Marina Cecelja
    King s College London British Heart Foundation Centre, Cardiovascular Division, Department of Clinical Pharmacology, St Thomas Hospital, London, United Kingdom
    Hypertension 54:1328-36. 2009
    ..The prognostic value of cfPWV may relate to a process of arterial ageing unrelated to classic risk factors other than hypertension...
  19. doi Quantitative 2D and 3D phase contrast MRI: optimized analysis of blood flow and vessel wall parameters
    A F Stalder
    Department of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Freiburg, Germany
    Magn Reson Med 60:1218-31. 2008
    ..Initial results in a patient with atherosclerosis suggest the potential of the method for understanding the formation and progression of cardiovascular diseases...
  20. ncbi Relationship between optic nerve head and finger blood flow
    Maneli Mozaffarieh
    University Eye Clinic, Basel, Switzerland
    Eur J Ophthalmol 20:136-41. 2010
    ..To examine the relationship between optic nerve head (ONH) and finger blood flow in subjects with and without a primary vascular dysregulation (PVD)...
  21. doi Aneurysm rupture following treatment with flow-diverting stents: computational hemodynamics analysis of treatment
    J R Cebral
    Center for Computational Fluid Dynamics, George Mason University, Fairfax, Virginia 22030, USA
    AJNR Am J Neuroradiol 32:27-33. 2011
    ..We analyzed 7 cases of aneurysms treated with flow diversion to explore the possible rupture mechanisms...
  22. doi Comparative velocity investigations in cerebral arteries and aneurysms: 3D phase-contrast MR angiography, laser Doppler velocimetry and computational fluid dynamics
    Dorothea I Hollnagel
    Institute of Neuroradiology, University Hospital Zurich, Zurich, Switzerland
    NMR Biomed 22:795-808. 2009
    ....
  23. ncbi Bidirectional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities in human retinal vessels
    René M Werkmeister
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    Opt Lett 33:2967-9. 2008
    ..We demonstrate that bidirectional color Doppler optical coherence tomography allows for the measurement of absolute blood flow values in vivo in human retinal vessels...
  24. pmc The relationship between shear stress and flow-mediated dilatation: implications for the assessment of endothelial function
    Kyra E Pyke
    Human Vascular Control Laboratory, School of Physical and Health Education, Queen s University, Kingston, ON, Canada
    J Physiol 568:357-69. 2005
    ....
  25. doi Flow-induced changes in pial artery compliance registered with a non-invasive method in rabbits
    Andrzej F Frydrychowski
    Institute of Human Physiology, Faculty of Health Sciences, Medical University of Gdansk, Tuwima Str 15, 80 210 Gdansk, Poland
    Microvasc Res 82:156-62. 2011
    This study was performed: 1) to assess the relationship between blood flow velocity in the internal carotid artery (CBF(ICA)) and pial artery pulsation (cc-TQ) and 2) to evaluate flow-induced changes in pial artery compliance.
  26. doi Maladaptive aortic properties in children after palliation of hypoplastic left heart syndrome assessed by cardiovascular magnetic resonance imaging
    Inga Voges
    Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital of Schleswig Holstein, Kiel, Germany
    Circulation 122:1068-76. 2010
    ..Therefore, we assessed the anatomy, elastic properties, and viability of the aorta and right ventricular function in patients with hypoplastic left heart syndrome by cardiovascular magnetic resonance imaging...
  27. doi Effects of the Valsalva maneuver on pial artery pulsation and subarachnoid width in healthy adults
    Magdalena Wszedybyl-Winklewska
    Institute of Human Physiology, Faculty of Health Sciences, Medical University of Gdansk, Tuwima Str 15, 80 210 Gdansk, Poland
    Microvasc Res 82:369-73. 2011
    ....
  28. doi Effects of acute hypercapnia on the amplitude of cerebrovascular pulsation in humans registered with a non-invasive method
    Andrzej F Frydrychowski
    Institute of Human Physiology, Faculty of Health Sciences, Medical University of Gdansk, Tuwima Str 15, 80 210 Gdansk, Poland
    Microvasc Res 83:229-36. 2012
    ..The aim of the study was to assess non-invasively the effects of acute hypercapnia on the amplitude of cerebrovascular pulsation (CVP) in humans...
  29. pmc In vivo photoacoustic imaging of transverse blood flow by using Doppler broadening of bandwidth
    Junjie Yao
    Department of Biomedical Engineering, Washington University in St Louis, St Louis, Missouri 63130, USA
    Opt Lett 35:1419-21. 2010
    ..By measuring bovine blood flowing through a plastic tube, the linear dependence of the broadening on the flow speed was validated. The blood flow of the microvasculature in a mouse ear and a chicken embryo (stage 16) was also studied...
  30. ncbi Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke
    Nozomi Nishimura
    Department of Physics, University of California at San Diego, La Jolla, California 92093, USA
    Nat Methods 3:99-108. 2006
    ..This demonstrates that a single blockage to a microvessel can lead to local cortical ischemia. Lastly, we show that hemodilution leads to a restoration of flow in secondary downstream vessels...
  31. pmc Determination of comprehensive arterial blood inflow in abdominal-pelvic organs: impact of respiration and posture on organ perfusion
    Takuya Osada
    Department of Sports Medicine for Health Promotion, Tokyo Medical University, Tokyo, Japan
    Med Sci Monit 17:CR57-66. 2011
    ..However, little information exists regarding the influence of respiration (interplay between inspiration and expiration) and posture on BFAP...
  32. doi Quantitative assessment of the microcirculation in healthy volunteers and in patients with septic shock
    Vanina S Kanoore Edul
    Servicio de Terapia Intensiva, Sanatorio Otamendi y Miroli, Buenos Aires, Argentina
    Crit Care Med 40:1443-8. 2012
    ..Our hypotheses were that 1) hyperdynamic blood flow is absent in septic shock; 2) nonsurvivors show more severe alterations than survivors; and 3) quantitative and semiquantitative microcirculatory parameters have a similar performance...
  33. pmc Noninvasive measurements and analysis of blood velocity profiles in human retinal vessels
    Zhangyi Zhong
    School of Optometry, Indiana University, Bloomington, Indiana 47405 3635, USA
    Invest Ophthalmol Vis Sci 52:4151-7. 2011
    ..To quantitatively model the changes in blood velocity profiles for different cardiac phases in human retinal vessels...
  34. doi Systemic and microcirculatory responses to progressive hemorrhage
    Arnaldo Dubin
    Facultad de Ciencias Medicas, Cátedra de Farmacología Aplicada, Universidad Nacional de La Plata, La Plata, Argentina
    Intensive Care Med 35:556-64. 2009
    ..To compare systemic hemodynamics with microcirculatory changes at different vascular beds during progressive hemorrhage...
  35. doi Accelerated phase-contrast MR imaging: comparison of k-t BLAST with SENSE and Doppler ultrasound for velocity and flow measurements in the aorta
    Andreas Stadlbauer
    MR Physics Group, Department of Radiology, Landesklinikum St Poelten, Austria
    J Magn Reson Imaging 29:817-24. 2009
    ..To evaluate differences in velocity and flow measurements in the aorta between accelerated phase-contrast (PC) magnetic resonance imaging (MRI) using SENSE and k-t BLAST and in peak velocity to Doppler ultrasound...
  36. doi Calcific aortic stenosis--time to look more closely at the valve
    Catherine M Otto
    N Engl J Med 359:1395-8. 2008
  37. doi RBC velocities in single capillaries of mouse and rat brains are the same, despite 10-fold difference in body size
    Miyuki Unekawa
    Department of Neurology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku ku, Tokyo 160 8582, Japan
    Brain Res 1320:69-73. 2010
    ..319bpm) and arterial blood pressure (86 vs. 84mmHg). We speculate that physical factors relating to oxygen exchange may constrain general RBC velocity in capillaries to a certain range for optimum oxygen exchange, regardless of species...
  38. doi The critical role of hemodynamics in the development of cerebral vascular disease
    Alexander M Nixon
    Department of Vascular Surgery, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Neurosurg 112:1240-53. 2010
    ..The recognition of WSS as an important factor in cerebral vascular disease may help to identify individuals at risk and guide treatment options...
  39. pmc Reduced ascending aortic strain and distensibility: earliest manifestations of vascular aging in humans
    Alban Redheuil
    Division of Cardiology, Johns Hopkins University, Baltimore, MD 21287, USA
    Hypertension 55:319-26. 2010
    ..In particular, compared with other measures of aortic function, the best markers of subclinical large artery stiffening, were AA distensibility in younger and aortic arch pulse wave velocity in older individuals...
  40. ncbi Lateralization of cerebral blood flow velocity changes during cognitive tasks. A simultaneous bilateral transcranial Doppler study
    G Vingerhoets
    Department of Psychiatry, University Ghent, Ghent, Belgium
    Stroke 30:2152-8. 1999
    Transcranial Doppler ultrasonography (TCD) permits the assessment of cognitively induced cerebral blood flow velocity (BFV) changes...
  41. doi Plasma fatty acid composition as a predictor of arterial stiffness and mortality
    Simon G Anderson
    Division of Cardiovascular and Endocrine Sciences, University of Manchester Medical School, 46 Grafton St, Manchester, M13 9NT United Kingdom
    Hypertension 53:839-45. 2009
    ..The results are consistent with an effect of dietary sources of n-3 long-chain polyunsaturates influencing arterial stiffness and mortality...
  42. ncbi Stiffness of capacitive and conduit arteries: prognostic significance for end-stage renal disease patients
    Bruno Pannier
    Service d Hemodialyse, Hôpital F H Manhès, Paris, France
    Hypertension 45:592-6. 2005
    ....
  43. ncbi Finite element modeling of three-dimensional pulsatile flow in the abdominal aorta: relevance to atherosclerosis
    C A Taylor
    Department of Surgery, Stanford University, CA, USA
    Ann Biomed Eng 26:975-87. 1998
    ..Monogr. Atheroscler. 15:13-19, 1990). This numerical investigation provides detailed quantitative data on hemodynamic conditions in the abdominal aorta heretofore lacking in the study of the localization of atherosclerotic disease...
  44. pmc Chronic optical access through a polished and reinforced thinned skull
    Patrick J Drew
    Department of Physics, University of California at San Diego, San Diego, California, USA
    Nat Methods 7:981-4. 2010
    ..We also repeatedly imaged dendritic spines, microglia and angioarchitecture, as well as used illumination to drive motor output via optogenetics and induce microstrokes via photosensitizers...
  45. doi Validation and reproducibility of aortic pulse wave velocity as assessed with velocity-encoded MRI
    Heynric B Grotenhuis
    Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands
    J Magn Reson Imaging 30:521-6. 2009
    ..To validate magnetic resonance imaging (MRI) assessment of aortic pulse wave velocity (PWV(MRI)) with PWV determined from invasive intra-aortic pressure measurements (PWV(INV)) and to test the reproducibility of the measurement by MRI...
  46. doi Noninvasive determination of carotid-femoral pulse wave velocity depends critically on assessment of travel distance: a comparison with invasive measurement
    Thomas Weber
    Cardiology Department, Klinikum Wels Grieskirchen, Grieskirchnerstrasse 42, Wels 4600, Austria
    J Hypertens 27:1624-30. 2009
    ..The aim of our study was to compare cfPWV, calculated with commonly used noninvasive methods for travel distance assessment, against aortic PWV measured invasively...
  47. ncbi Color Doppler imaging in ocular hypertension and open-angle glaucoma
    Cengiz Akarsu
    Department of Ophthalmology, University of Kirikkale, Kirikkale, 71100, Turkey
    Graefes Arch Clin Exp Ophthalmol 242:125-9. 2004
    ..To quantify the retrobulbar hemodynamics of patients with ocular hypertension and open-angle glaucoma and to compare it with that of normal subjects...
  48. ncbi Cardiac output and central distribution of blood flow in the human fetus
    G Mielke
    Department of Obstetrics and Gynecology, University of Tuebingen, Tuebingen, Germany
    Circulation 103:1662-8. 2001
    ..The objectives of this study were to establish reference ranges for left and right cardiac output and to investigate blood flow distribution through the foramen ovale, ductus arteriosus, and pulmonary bed in human fetuses...
  49. ncbi Reproducibility of the blood flow index as noninvasive, bedside estimation of cerebral blood flow
    Bendicht P Wagner
    Pediatric Intensive Care, Department of Pediatrics, Inselspital, University of Berne, 3010, Berne, Switzerland
    Intensive Care Med 29:196-200. 2003
    ..To investigate the feasibility and reproducibility of the blood flow index (BFI) method for measuring cerebral blood flow...
  50. doi Use of laser speckle flowgraphy in ocular blood flow research
    Tetsuya Sugiyama
    Department of Ophthalmology, Osaka Medical College, Japan
    Acta Ophthalmol 88:723-9. 2010
    ..Unresolved issues concern the effect of pupil size on measurement results, the effects of various stimulations, and how to measure choroidal and retinal blood flow velocity separately without using the blue-component of argon laser.
  51. ncbi Diffuse optical measurement of blood flow in breast tumors
    Turgut Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Opt Lett 30:2915-7. 2005
    ..Increased blood flow was observed in tumor regions relative to healthy tissue, and control subjects did not exhibit significant blood flow heterogeneity. The measurements introduce a new optical contrast for diffuse optical mammography...
  52. doi Effect of antihypertensive agents on cerebral blood flow and flow velocity in acute ischaemic stroke: systematic review of controlled studies
    Gillian M Sare
    Stroke Trials Unit, Institute of Neuroscience, University of Nottingham, Nottingham, UK
    J Hypertens 26:1058-64. 2008
    ..Lowering blood pressure might improve outcome, provided it does not reduce cerebral blood flow in the presence of dysfunctional cerebral autoregulation...
  53. ncbi Histomorphology of the placenta and the placental bed of growth restricted foetuses and correlation with the Doppler velocimetries of the uterine and umbilical arteries
    R Madazli
    Department of Obstetrics and Gynecology, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey
    Placenta 24:510-6. 2003
    ..The most severe clinical outcomes and perinatal mortality are present when both uterine and umbilical districts are altered...
  54. pmc Mechanotransduction in vascular physiology and atherogenesis
    Cornelia Hahn
    Department of Microbiology, University of Virginia, Charlottesville, Virginia 22908, USA
    Nat Rev Mol Cell Biol 10:53-62. 2009
    ....
  55. pmc Arterial stiffness in mild-to-moderate CKD
    Ashish Upadhyay
    Renal Section, Boston Medical Center and Boston University School of Medicine, Boston, Massachusetts, USA
    J Am Soc Nephrol 20:2044-53. 2009
    ..Baseline arterial measures did not associate with incident CKD or incident microalbuminuria. In summary, arterial stiffness correlates with albuminuria but not with mild-to-moderate CKD...
  56. doi Changes in wall motion and blood flow in the outflow tract of chick embryonic hearts observed with optical coherence tomography after outflow tract banding and vitelline-vein ligation
    Sandra Rugonyi
    Division of Biomedical Engineering, Oregon Health and Science University, 3303 SW Bond Ave, CH13B, Portland, OR 97239, USA
    Phys Med Biol 53:5077-91. 2008
    ..Our results therefore establish the utility of spectral domain OCT to study the influence of hemodynamic conditions on heart development in intact, in vivo chicken embryo models...
  57. ncbi Elevated E/E' predicts prognosis in congestive heart failure patients with preserved systolic function
    Hiroyuki Okura
    Division of Cardiology, Bell Land General Hospital, Sakai, Japan
    Circ J 73:86-91. 2009
    ..The purpose of this study was to investigate whether E/E' predicts prognosis in HFPSF...
  58. doi Bicuspid aortic valve: four-dimensional MR evaluation of ascending aortic systolic flow patterns
    Michael D Hope
    Department of Radiology, University of California San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143 0628, USA
    Radiology 255:53-61. 2010
    ....
  59. ncbi Retrobulbar blood flow in glaucoma patients with nocturnal over-dipping in systemic blood pressure
    D Gherghel
    University Eye Clinic, Basel, Switzerland
    Am J Ophthalmol 132:641-7. 2001
    ....
  60. ncbi Photoplethysmographic assessment of pulse wave reflection: blunted response to endothelium-dependent beta2-adrenergic vasodilation in type II diabetes mellitus
    P J Chowienczyk
    Department of Clinical Pharmacology, Centre for Cardiovascular Biology and Medicine, King s College, London, United Kingdom
    J Am Coll Cardiol 34:2007-14. 1999
    ..We sought to determine whether a simple index of pressure wave reflection may be derived from the digital volume pulse (DVP) and used to examine endothelium-dependent vasodilation in patients with type II diabetes mellitus...
  61. ncbi Blood flow and vessel mechanics in a physiologically realistic model of a human carotid arterial bifurcation
    S Z Zhao
    Department of Chemical Engineering and Chemical Technology, Imperial College, London, UK
    J Biomech 33:975-84. 2000
    ..Stress concentration occurs at both the anterior and posterior aspects of the proximal internal bulb. These are also regions of low wall shear stress. The comparison of computed and measured wall movement generally shows good agreement...
  62. ncbi Vasospasm probability index: a combination of transcranial doppler velocities, cerebral blood flow, and clinical risk factors to predict cerebral vasospasm after aneurysmal subarachnoid hemorrhage
    Nestor R Gonzalez
    Division of Neurosurgery, David Geffen School of Medicine, University of California at Los Angeles, California 90025 7039, USA
    J Neurosurg 107:1101-12. 2007
    ..The goal in this study was to create an index (vasospasm probability index [VPI]) to improve diagnostic accuracy for vasospasm after subarachnoid hemorrhage (SAH)...
  63. ncbi Validation of a new non-invasive portable tonometer for determining arterial pressure wave and pulse wave velocity: the PulsePen device
    Paolo Salvi
    Department of Internal Medicine, Bufalini Hospital, Cesena, Italy
    J Hypertens 22:2285-93. 2004
    ..Its software provides absolute arterial pressure values, an assessment of arterial pulse wave contours, an estimation of reflection waves and measurements of PWV...
  64. ncbi Characterization of volumetric flow rate waveforms in the normal internal carotid and vertebral arteries
    Matthew D Ford
    Imaging Research Labs, Robarts Research Institute and Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada
    Physiol Meas 26:477-88. 2005
    ..This capability may be of particular utility for studies where cerebrovascular flow dynamics are required, but only average flow rates are available...
  65. ncbi Modelling the circle of Willis to assess the effects of anatomical variations and occlusions on cerebral flows
    J Alastruey
    Department of Aeronautics, South Kensington Campus, Imperial College London, SW7 2AZ, UK
    J Biomech 40:1794-805. 2007
    ..Finally, we study the effect of partial occlusions of the communicating arteries on the cerebral flows, which again confirms that the ACoA is a more important collateral pathway than the PCoAs if an ICA is occluded...
  66. ncbi Noninvasive measurement of time-varying three-dimensional relative pressure fields within the human heart
    T Ebbers
    Department of Medicine and Care, Clinical Physiology and Linköping, Sweden
    J Biomech Eng 124:288-93. 2002
    ..Noninvasive simultaneous assessment of cardiac pressure and flow phenomena is an important new tool for studying cardiac fluid dynamics...
  67. ncbi Water drinking acutely improves orthostatic tolerance in healthy subjects
    Christoph Schroeder
    Franz Volhard Clinical Research Center, Medical Faculty of the Charite, Humboldt University, Berlin, Germany
    Circulation 106:2806-11. 2002
    ..In patients with severe autonomic dysfunction, water drinking elicits an acute pressor response and improves orthostatic hypotension. We tested the hypothesis that water drinking also improves orthostatic tolerance in healthy subjects...
  68. ncbi How can blood flow be measured?
    Leopold Schmetterer
    Department of Clinical Pharmacology, Medical University of Vienna, Austria
    Surv Ophthalmol 52:S134-8. 2007
    ..This article aims to review the different techniques available today for the assessment of ocular blood flow. Furthermore the advantages and the possible limitations of the techniques are discussed...
  69. pmc Cerebral dominance for language function in adults with specific language impairment or autism
    Andrew J O Whitehouse
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, UK
    Brain 131:3193-200. 2008
    ..3%). These findings suggest that atypical cerebral dominance is not implicated in all cases of poor language development (i.e. ASD and SLI-history groups), but may act as a biological marker of persisting SLI...
  70. ncbi Magnetic resonance imaging of blood flow with a phase subtraction technique. In vitro and in vivo validation
    A J Evans
    Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710
    Invest Radiol 28:109-15. 1993
    ..A velocity-encoding phase subtraction technique was used to measure the velocity and flow rate of fluid flow in a phantom and blood flow in volunteers...
  71. pmc Contribution of oxygen-sensitive neurons of the rostral ventrolateral medulla to hypoxic cerebral vasodilatation in the rat
    E V Golanov
    Department of Neurology and Neuroscience, Cornell University Medical College, New York, NY 10021, USA
    J Physiol 495:201-16. 1996
    ....
  72. ncbi Diagnostic value of Doppler assessment of the hepatic and portal vessels and ultrasound of the spleen in liver disease
    John O'Donohue
    Institute of Liver Studies, King s College Hospital, London, UK
    Eur J Gastroenterol Hepatol 16:147-55. 2004
    ....
  73. ncbi Pulmonary arterial hypertension: noninvasive detection with phase-contrast MR imaging
    Javier Sanz
    Zena and Michael A Wiener Cardiovascular Institute, Marie Josee and Henry R Kravis Center for Cardiovascular Health, Mount Sinai School of Medicine, New York, NY 10029, USA
    Radiology 243:70-9. 2007
    ..To retrospectively identify pulmonary arterial (PA) flow parameters measured with phase-contrast magnetic resonance (MR) imaging that allow noninvasive diagnosis of chronic PA hypertension (PAH)...
  74. ncbi Parametric imaging of myocardial blood flow with 15O-water and PET using the basis function method
    Hiroshi Watabe
    Department of Investigative Radiology, National Cardiovascular Center Research Institute, Osaka, Japan
    J Nucl Med 46:1219-24. 2005
    ..The basis function method linearizes the solution of the 1-tissue-compartment model, which results in a computationally much faster method than the conventional nonlinear least-squares fitting method in estimating the parameters...
  75. ncbi Effects of epoprostenol on right ventricular hypertrophy and dilatation in pulmonary hypertension
    Roald J Roeleveld
    Department of Pulmonology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Chest 125:572-9. 2004
    ..To gain more knowledge of changes in main pulmonary artery flow and right ventricular mass and volumes in patients with pulmonary hypertension during epoprostenol therapy...
  76. ncbi Effect of endothelial shear stress on the progression of coronary artery disease, vascular remodeling, and in-stent restenosis in humans: in vivo 6-month follow-up study
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
    Circulation 108:438-44. 2003
    ..The endothelium controls local arterial responses by transduction of shear stress. Characterization of endothelial shear stress (ESS) may allow for prediction of progression of atherosclerosis and in-stent restenosis...
  77. pmc Nonlinear assessment of cerebral autoregulation from spontaneous blood pressure and cerebral blood flow fluctuations
    Kun Hu
    Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, 812 Stoneman Bldg, 330 Brookline Avenue, Boston, MA 02115, USA
    Cardiovasc Eng 8:60-71. 2008
    ..relied on the quantification of the relationship between noninvasive beat-to-beat blood pressure (BP) and blood flow velocity (BFV)...
  78. pmc Neutrophil adhesion and activation under flow
    Alexander Zarbock
    Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA
    Microcirculation 16:31-42. 2009
    ..This review provides an overview of signaling in rolling and adherent neutrophils...
  79. ncbi Age-associated changes in regional aortic pulse wave velocity
    W J Rogers
    Department of Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212, USA
    J Am Coll Cardiol 38:1123-9. 2001
    ..This study was designed to determine noninvasively the age-associated changes in regional mechanical properties in normals using phase-contrast magnetic resonance imaging (PCMRI)...
  80. ncbi Wall shear stress--an important determinant of endothelial cell function and structure--in the arterial system in vivo. Discrepancies with theory
    Robert S Reneman
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, Maastricht, The Netherlands
    J Vasc Res 43:251-69. 2006
    ..Applications of wall shear stress as in flow-mediated arterial dilation, clinically in use to assess endothelial cell (dys)function, are also addressed. This review starts with some background considerations and some theoretical aspects...
  81. ncbi Autonomic neural control of dynamic cerebral autoregulation in humans
    Rong Zhang
    Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, and The University of Texas Southwestern Medical Center at Dallas, Tex 75231, USA
    Circulation 106:1814-20. 2002
    ..The purpose of the present study was to determine the role of autonomic neural control of dynamic cerebral autoregulation in humans...
  82. ncbi Increased pulse wave velocity is not associated with elevated augmentation index in patients with diabetes
    Peter S Lacy
    Department of Cardiovascular Sciences, Cardiovascular Research Institute, University of Leicester, Leicester LE2 7LX, UK
    J Hypertens 22:1937-44. 2004
    ..This study compares the relationship between PWV and AI in people with and without diabetes...
  83. ncbi Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure
    R Hambrecht
    University of Leipzig, Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    Circulation 98:2709-15. 1998
    ..Local handgrip exercise has previously been shown to enhance endothelium-dependent vasodilation in conduit and resistance vessels in CHF...
  84. ncbi The in vivo effects of the Pro12Ala PPARgamma2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank
    G D Tan
    Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, University of Oxford, Oxford OX3 7LJ, UK
    Diabetologia 49:158-68. 2006
    ..We hypothesised that Ala12 allele carriers demonstrate greater adipose tissue metabolic flexibility and insulin sensitivity...
  85. ncbi Flow measurement by magnetic resonance: a unique asset worth optimising
    Philip J Kilner
    CMR Unit, Royal Brompton Hospital, Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney Street, London, UK
    J Cardiovasc Magn Reson 9:723-8. 2007
    ..Awareness of the potential problems and concerted efforts towards optimisation are needed from manufacturers and users to make appropriate use of phase contrast flow measurement - a unique strength of cardiovascular magnetic resonance...
  86. pmc Differences in aortic arch geometry, hemodynamics, and plaque patterns between C57BL/6 and 129/SvEv mice
    Hui Zhu
    Department of Biomedical Engineering, Duke University, Durham, NC 27708 0281
    J Biomech Eng 131:121005. 2009
    ..These results support the notion that heritable features of arterial geometry can contribute to individual differences in local susceptibility to arterial disease...
  87. pmc Molecular imaging of the initial inflammatory response in atherosclerosis: implications for early detection of disease
    Beat A Kaufmann
    Cardiovascular Division, UHN 62, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
    Arterioscler Thromb Vasc Biol 30:54-9. 2010
    ..Background- We hypothesized that molecular imaging of endothelial cell adhesion molecule expression could noninvasively evaluate prelesion atherogenic phenotype...
  88. doi The efficacy of a new stimulation technology to increase venous flow and prevent venous stasis
    M Griffin
    The Vascular Noninvasive Screening and Diagnostic Centre, 30 Weymouth Street, London W1G 7BS, UK
    Eur J Vasc Endovasc Surg 40:766-71. 2010
    ..The aim was to determine: (a) dependence of venous blood velocity and ejected volume on the rates of stimulated calf contractions: (b) clinical factors affecting efficacy in healthy individuals...
  89. pmc Rapid flow assessment of congenital heart disease with high-spatiotemporal-resolution gated spiral phase-contrast MR imaging
    Jennifer A Steeden
    Centre for Medical Image Computing, UCL Department of Medical Physics and Bioengineering, London, England
    Radiology 260:79-87. 2011
    ..To validate a prospectively triggered spiral phase-contrast magnetic resonance (MR) sequence accelerated with sensitivity encoding (SENSE) in a population of children and adults with congenital heart disease...
  90. ncbi Aortic pulse wave velocity predicts cardiovascular mortality in subjects >70 years of age
    S Meaume
    Geriatrics Department of Charles-Foix Hospital, Limeil-Brevannes, France
    Arterioscler Thromb Vasc Biol 21:2046-50. 2001
    ..In subjects 70 to 100 years old, aortic PWV is a strong, independent predictor of cardiovascular death, whereas systolic or pulse pressure was not. This prospective result will need to be confirmed in an intervention trial...
  91. doi Use of colour Doppler imaging in ocular blood flow research
    Ingeborg Stalmans
    Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium
    Acta Ophthalmol 89:e609-30. 2011
    ..The intention of this review is to standardize methods in CDI assessment that are used widely, but not to exclude other approaches or additional tests that individual laboratories may choose or continue to use...
  92. ncbi Flow velocity vector fields by ultrasound particle imaging velocimetry: in vitro comparison with optical flow velocimetry
    John Westerdale
    Department of Mechanical and Aerospace Engineering, Ira A Fulton School of Engineering, Arizona State University, Tempe, AZ 85287, USA
    J Ultrasound Med 30:187-95. 2011
    ..We performed an in vitro study to assess the precision and accuracy of particle imaging velocimetry (PIV) data acquired using a clinically available portable ultrasound system via comparison with stereo optical PIV...
  93. doi Improved aortic pulse wave velocity assessment from multislice two-directional in-plane velocity-encoded magnetic resonance imaging
    Jos J M Westenberg
    Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands
    J Magn Reson Imaging 32:1086-94. 2010
    ..To evaluate the accuracy and reproducibility of aortic pulse wave velocity (PWV) assessment by in-plane velocity-encoded magnetic resonance imaging (MRI)...
  94. doi Brachial-ankle pulse wave velocity predicts all-cause mortality in the general population: findings from the Takashima study, Japan
    Tanvir Chowdhury Turin
    Department of Health Science, Shiga University of Medical Science, Shiga, Japan
    Hypertens Res 33:922-5. 2010
    ..8 (95% confidence interval: 1.4-32.8) as compared with the lowest tertile. The present study demonstrated that increased baPWV is an independent predictor of all-cause mortality in the Japanese population...
  95. doi Tetralogy of fallot: 3D velocity-encoded MR imaging for evaluation of right ventricular valve flow and diastolic function in patients after correction
    Annelies E van der Hulst
    Division of Pediatric Cardiology, Department of Pediatrics, Leiden University Medical Center, RC, Leiden, The Netherlands
    Radiology 256:724-34. 2010
    ....
  96. doi Arterial stiffness, physical function, and functional limitation: the Whitehall II Study
    Eric J Brunner
    Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
    Hypertension 57:1003-9. 2011
    ..The nature of the link between arterial stiffness and quality of life in older people merits attention...
  97. doi Patient-specific modeling of cardiovascular mechanics
    C A Taylor
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Annu Rev Biomed Eng 11:109-34. 2009
    ..Applications of patient-specific models of cardiovascular mechanics are presented, followed by a discussion of the challenges and opportunities that lie ahead...
  98. pmc Sequence optimization to reduce velocity offsets in cardiovascular magnetic resonance volume flow quantification--a multi-vendor study
    Marijn P Rolf
    Department of Physics and Medical Technology, ICaR VU, VU University Medical Center, Amsterdam, The Netherlands
    J Cardiovasc Magn Reson 13:18. 2011
    ..This study is aimed at identifying correlations between protocol parameters and the resulting velocity error in clinical CMR flow measurements in a multi-vendor study...
  99. doi Can Doppler ultrasonographic indices of the renal artery predict the presence of supernumerary renal arteries?
    K Ghabili
    Tuberculosis and Lung Diseases Research Center, Tabriz University Medical Sciences, Tabriz, Iran
    Transplant Proc 41:2731-3. 2009
    ..However, this modality is expensive and invasive. The aim of this study was to assess whether Doppler ultrasonographic (DU) indices of the renal artery could predict the presence of supernumerary renal arteries...
  100. pmc Improved accuracy in flow mapping of congenital heart disease using stationary phantom technique
    Thomas A Miller
    Department of Pediatrics, Maine Medical Center, 22 Bramhall St, Portland, ME, USA
    J Cardiovasc Magn Reson 11:52. 2009
    ..Previous reports have highlighted the presence of inherent errors in flow mapping that are improved with the use of a stationary phantom control. To our knowledge, these studies have only been performed in healthy volunteers...
  101. doi Age-related changes of regional pulse wave velocity in the descending aorta using Fourier velocity encoded M-mode
    Valentina Taviani
    Department of Radiology, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
    Magn Reson Med 65:261-8. 2011
    ..There was a preferential stiffening of the thoracic aorta with age, which may be due to progressive fragmentation of elastin fibers in this region...

Research Grants78

  1. Circulatory Dysfunction in Chronic Fatigue Syndrome
    Julian Stewart; Fiscal Year: 2004
    ..Cerebral blood flow velocity (CBFv) will be estimated by transcranial Doppler ultrasonography...
  2. FUNCTIONAL ASPECTS OF OXYGEN DELIVERY
    Marcos Intaglietta; Fiscal Year: 2004
    ..of microvascular transport properties including micro-p02 and micro-NO measurements in blood and tissue, blood flow velocity, functional capillary density and arteriolar reactivity...
  3. Neurodevelopmental Outcomes in Infants with HLHS after Hybrid Stage I Palliation
    Sharon L Hill; Fiscal Year: 2010
    ..objective of this research proposal is to test the hypothesis that a correlation exists between cerebral blood flow velocity and neurodevelopmental outcomes in hypoplastic left heart syndrome babies who have undergone Hybrid Stage I ..
  4. Neurodevelopmental Outcomes in Infants with HLHS after Hybrid Stage I Palliation
    Sharon Hill; Fiscal Year: 2009
    ..objective of this research proposal is to test the hypothesis that a correlation exists between cerebral blood flow velocity and neurodevelopmental outcomes in hypoplastic left heart syndrome babies who have undergone Hybrid Stage I ..
  5. Muscle Reflex Control of the Coronary Circulation
    Lawrence I Sinoway; Fiscal Year: 2010
    ..Over the past 5 to 6 years we have worked hard to develop the duplex method to examine renal blood flow velocity. This has resulted in a series of papers that have defined the role of muscle mechanoreceptors in ..
  6. Muscle Reflex Control of the Coronary Circulation
    Lawrence Sinoway; Fiscal Year: 2009
    ..Over the past 5 to 6 years we have worked hard to develop the duplex method to examine renal blood flow velocity. This has resulted in a series of papers that have defined the role of muscle mechanoreceptors in ..
  7. Label-free optical imaging of 3D structural and functional microcirculations
    Ruikang Wang; Fiscal Year: 2009
    ..technique is based on the linear relationship between phase-changes in the optical fOMAG signals and the blood flow velocity when fOMAG images the tissue; 3) Map the oxygenation status of the blood perfusion by a novel spectroscopic ..
  8. Label-free optical imaging of 3D structural and functional microcirculations
    Ruikang Wang; Fiscal Year: 2010
    ..technique is based on the linear relationship between phase-changes in the optical fOMAG signals and the blood flow velocity when fOMAG images the tissue;3) Map the oxygenation status of the blood perfusion by a novel spectroscopic ..
  9. Cerebral Blood Flow Model for Normo/Hypertensive Elderly
    METTE OLUFSEN; Fiscal Year: 2002
    ..The specific aim is to develop a lumped parameter model that can reproduce a dynamic changes of pulsatile blood flow velocity (BFV) and pressure (BP) in the middle cerebral artery (MCA) during posture change from sitting to standing, ..
  10. Data Mining Based Noninvasive Intracranial Pressure Assessment
    Xiao Hu; Fiscal Year: 2007
    ..from a signal database that contains records of simultaneous arterial blood pressure (ABP) and cerebral blood flow velocity (CBFV) from a population of patients...
  11. ORTHOSTATIC INTOLERANCE IN CFS
    Roy Freeman; Fiscal Year: 2006
    ..using the Evans Blue dye method; venous compliance using venous occlusion plethysmography; and cerebral blood flow velocity with transcranial Doppler...
  12. Exploring the Physiology of Short-term Control of Cerebral Blood Flow in Humans
    J Andrew Taylor; Fiscal Year: 2010
    ..Beat-by-beat assessment of cerebral blood flow velocity has shown that cerebral flow is regulated not just over minutes and hours but also on shorter time scales ..
  13. Vitamin B6, Vascular Dysfunction and Adhesion Molecules in Sickle Cell Disease
    Ralph Green; Fiscal Year: 2007
    ..soluble adhesion molecules known to be related to vascular injury (by real-time multiplex assay), and blood flow velocity and microvessel morphometry (by direct real-time computer-assisted intravital microscopy)...
  14. TRANSFUSION TRIGGER EXTENSION BY PLASMA EXPANDERS
    Marcos Intaglietta; Fiscal Year: 2003
    ..hypothesis by direct in vivo measurement of micro-p02 and micro-NO in blood and tissue, capillary pressure, blood flow velocity, functional capillary density and arteriolar reactivity...
  15. Tyrosine Hydroxylase Sry and Hypertension
    Daniel Ely; Fiscal Year: 2009
    ..Blood pressure will be measured by telemetry and blood flow velocity by Doppler flow probe in conscious animals...
  16. LOOP-GAP RESONATOR COILS FOR MRI AND 31-P SPECTROSCOPY
    James Hyde; Fiscal Year: 1993
    ..Applications focus on tissue grafts and possible rejection including kidneys, heart and skin...
  17. ULTRASONIC INSTRUMENTATION FOR CARDIOVASCULAR STUDIES
    Craig Hartley; Fiscal Year: 2004
    ..The developed methods will allow measurement and evaluation oi? cardiac timing, blood flow velocity, arterial pulse wave velocity, arterial impedance spectra, fluid dynamies, blood viscosity;flow ..
  18. NON-INVASIVE EVALUATION OF ICP AND HEMODYNAMICS
    David Newell; Fiscal Year: 2004
    ..Transcranial Doppler (TCD) can be used to continuously record blood flow velocity from the intracranial vessels which then can be used in combination with arterial blood pressure (ABP) ..
  19. LICIT & ILLICIT ABUSED STIMULANT DRUGS
    ROLAND GRIFFITHS; Fiscal Year: 2004
    ..One study will explore the use of cerebral blood flow velocity and quantitative EEG as sensitive physiological measures of caffeine withdrawal...