cardiovascular diagnostic techniques

..The value of endothelial function as a surrogate endpoint in cardiovascular studies is critically reviewed...

..The aim of this study was to detect the long-term association of peripheral vascular endothelial function and clinical outcome in healthy subjects without apparent coronary artery disease (CAD)...

..The purpose of this study is to determine if an ankle-brachial index (ABI) >or=1.40 is associated with reduced quality of life (QoL)...

..The study was specially aimed at assessing whether brachial artery flow-mediated dilation (FMD) added to the predictive value of ankle-brachial pressure index (ABPI)...

..These results suggest that FMD, IMT and PWV are related to each other, but the combination of these measurements will be of stronger clinical relevance...

..This article will review the growing literature in an effort to evaluate methods of assessment of endothelial function and its clinical utility...

..A detailed discussion of these issues forms the basis of this review...

..If a patient is found to have abnormal non-invasive test, this patient can be elevated to a higher risk category...

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..Finally, the effects of current and future cardiovascular drugs on arterial stiffness are also discussed, as is the relationship between arterial elasticity and endothelial function...

..In the Prospective Study of the Vasculature in Uppsala Seniors (PIVUS) study, different techniques to assess vasodilation in conduit and resistance arteries were evaluated in relation to the MetS and insulin resistance...

..A relatively simple, invasive method for quantitatively assessing the status of the coronary microcirculation independent of the epicardial artery is lacking...

..This study aimed to evaluate the feasibility and usefulness of these techniques in the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study...

..CONCLUSION: In patients with mild coronary endothelial dysfunction, forearm vasoreactivity is related to the coronary response, provided that the same stimulus is used...

..These measurements may offer useful tools for assessment of endothelial function...

..This article introduces the author's early experience using B-flow in the abdomen, and illustrates the potential advantages this technique offers relative to Doppler flow mapping...

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..Such markers have gained popularity for research and clinical use. This paper reviews recent studies using noninvasive technology for detection and monitoring of cardiovascular disease as it pertains to diabetes patients...

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..Finally, a mention is made of the relevance of tele-medicine to education and the costs related to cardiology, with an indication of some future needs for tele-cardiology...

..This statement summarises the principles that should guide developments in cardiovascular diagnostic services...

..However, these studies did not measure network performance in real time, when a significant amount of data required for network function may not be available. They also did not use chemical cardiac marker data...

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..Advances in computer technology have made sophisticated devices, such as the gated SPECT, a routine part of cardiology...

..The clinical significance of CTR in non-diabetic maintenance hemodialysis (MHD) patients remains unclear...

..To briefly survey the literature for the past 2-3 years on the subject of diagnostic and prognostic markers of endothelial cell dysfunction...

..Thus, it is the management for both situations of the heart and the artery that matters, and AI can be regarded as a new marker of cardiovascular disease for suitable clinical management on both heart and artery...

..The Allen test is a widely used screening method of hand circulation. Our aim was to study whether the Allen test alone gives sufficient information for harvesting the radial artery in coronary artery bypass grafting...

..Retinal arteriolar diameter, blood velocity and blood flow increased significantly in response to a hypercapnic provocation in young, healthy subjects...

..9). This innovative approach could significantly contribute to detecting and evaluating arterial stenoses, and to characterize the elasticity of the artery...

..This study was undertaken to determine the natural history of physical function in older men limited by intermittent claudication...

..To study recent practice patterns in radionuclide myocardial perfusion imaging (MPI) and related procedures among radiologists, cardiologists, and other physicians...

..The usefulness of other methods used in population studies, such as pulse wave analysis using a beta-2 receptor agonist as vasodilator and the hyperaemic blood flow velocity have to be further validated...

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..Comprehensive solutions will require addressing the barriers at the system, the provider, and the patient level. An early intervention approach that addresses multiple risk factors should be a high priority...

..Thus, it becomes important to understand the PTTR normality and difference of hypertensive children when compared to those measured from normotensive children...

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..Genetic markers of EH may improve the understanding of individual differences in susceptibility to develop hypertension and LV hypertrophy...

..Reversibility of baPWV suggests that vessel damage is not so serious and may be only endothelial dysfunction. Therefore baPWV should be monitored and ameliorated in treating metabolic syndrome...

..Larger studies are needed to define the criteria for selecting the patients who will benefit from valve replacement...

..To measure the predictive value and diagnostic performance of clinical features used to diagnose coronary syndromes in patients presenting with acute, undifferentiated chest pain...

..CONCLUSIONS: IL-6 and sIL-6R are markers of acute coronary syndromes and may be used for the identification of high-risk patients with unstable angina or AMI...

..To compare differences in the presentation and management of acute coronary syndrome (ACS) patients presenting to interventional versus non-interventional New Zealand hospitals...

..This view had the best correlation with transthoracic LA measurements: r = 0.79 for TEE long axis (CI 0.71-0.85), P <.0001...

..We investigated the agreement between SVV and PPV, as well as the reliability of LiDCO- and PiCCO-measured SVV, PPV and ITBVI, in detecting fluid responsiveness before and after fluid challenge (FC)...

..We will outline some of the changes in the conceptual approach that we consider important to the treatment of complex aortic disease...

..63) is likely attributable to the variability of blood pressure measurements. This study confirms that vascular measurements demonstrate substantial reliability in preschool-aged children as young as 2 years...

..Improving diagnostic skills remains a continuous challenge for clinicians. Simple and reliable diagnostic procedures are crucial to comply with Guidelines and reduce healthcare utilisation and costs...

..To evaluate the impact of a laboratory course on the manual blood pressure (BP) and heart rate (HR) measurement skills of pharmacy students...

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..To assess the medical and economic impact of preoperative cardiac testing (stress thallium imaging or echocardiography) on the treatment of elderly patients with hip fractures...

..We evaluated the efficacy of the intracoronary (IC) continuous adenosine infusion method via a microcatheter for inducing maximal coronary hyperemia...

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..Differentiating benign causes from those resulting from clinically significant cardiac arrhythmia can be challenging and the clinical examination may aid in this process...

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..It is in the best interest of nuclear cardiology and patients to pursue the latter course...

..With a suitable combination of new methods, it is likely that more patients can be managed as outpatients, that length of stay can be shortened for those admitted, and that some patients with ACS can get earlier treatment...

..Advances in technique can reduce radiation dose by 90%. With appropriate patient selection, cardiac CT can accurately diagnose heart disease, markedly decrease health care costs, and reliably predict clinical outcomes...

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..Our pressure chamber has been stress tested to 100 mmHg below atmospheric pressure and has been used successfully to test orthostatic tolerance and physiological responses to -50 mmHg...

..The limitation that some cardiovascular control mechanisms affect the same frequency components of BPV requires the combination of blood pressure spectral analysis with other techniques...

..Future research of EIMs in patients with ACS might provide evidence of easy-to-measure and economically feasible markers that are sound prognosticators...

..Therefore, before clinically applying HTS-MCG systems to the detection of repolarization abnormalities in acute coronary syndromes, further technical development of the systems is necessary to improve the signal-to-noise ratio...

..The clinical presentation varies and may mimic other more common disease processes. Early recognition on the basis of a focused history, physical examination, appropriate diagnostic studies, and management is essential for good outcomes...

..There are a few concise studies reporting that FMD predicts cardiovascular events. However, the assumption that focal measurement of brachial artery FMD predicts coronary artery disease deserves further investigation...

..To educate pharmacists about the application of laboratory values in oncology...

..A young primiparous lady presented with drug-refractory atrial tachycardia which had led to cardiomyopathy. Three attempts with electrical cardioversion were also unsuccessful. She was rescued by radiofrequency ablation...

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..Concerns have been expressed about quality of for-profit hospitals and their use of expensive technologies...

..Working conditions and the environment may contribute to the multi-factorial aetiology of cardiovascular disease...

..Finally, the overrepresentation of ethnic minority groups in MESA will allow for testing of interactions with ethnicity. We are unaware of any other population-based study adequate to study the stated aims. ..

..We are unaware of any other population-based study that is as comprehensive as this to study the stated aims. ..

..The experiments described herein will provide a sound mechanistic basis for the future translation of this body of work to the clinical domain. (End of Abstract) ..

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..This will provide valuable information for the development of novel therapeutic interventions and improved management of diabetic patients with cardiac disease...

..The investigations may shed light on mechanisms of premature senescence of endothelial cells, role of peroxynitrite in initiating it, and potential therapeutic efficacy of peroxynitrite scavenging in amelioration of vasculopathy. ..

..Number of publicationsand manuscriptsacceptedfor publication (not to exceed 10) 10 Other items (list): 1. Color illustrations from the grant application 2. Movies - intravital videomicroscopy supplement ..

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..The device will widely be applied to various biomedical instruments that require wavelength differentiation and selection. ..

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..It is anticipated that novel therapeutic strategies should be disclosed, which could be applicable to prevention of acute renal failure. ..

..Furthermore, formal research presentations by the trainees will be given biannually to the local research community. ..

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..This familial condition where the heart grows too thick is the most common cause of sudden death in young people and athletes. ..

..The public health significance of this project is that we aim to protect patients from severe cardiotoxic effects of anti-cancer drugs, which in many cases, limits the use of otherwise effective therapies. ..

..Occurrence of MACE will be followed for 2 years. Data will be analyzed using logistic regression and survival analysis. ..

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..Occurrence of MACE will be followed for 2 years. Data will be analyzed using logistic regression and survival analysis. ..

..It is anticipated that novel therapeutic strategies should be disclosed, which could be applicable to prevention of acute renal failure. ..

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..This study will facilitate translation of research findings on carotid lesions into clinical practice for identifying and treating those patients who are more likely to have an unstable plaque. ..

..The impending surgical intervention will allow histopathological evaluation of the endarterectomy specimens to define potential utility of annexin imaging. ..

..If proven to be correct, this hypothesis could delineate new therapeutic approaches to prevent the progression of diabetic nephropathy. ..

..The public health significance of this project is that we aim to protect patients from severe cardiotoxic effects of anti-cancer drugs, which in many cases, limits the use of otherwise effective therapies. ..

..Occurrence of MACE will be followed for 2 years. Data will be analyzed using logistic regression and survival analysis. ..

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..The extent of inflammation and MMP expression in the plaques will be ascertained histopathologically. (End of Abstract) ..

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..The public health significance of this project is that we aim to protect patients from severe cardiotoxic effects of anti-cancer drugs, which in many cases, limits the use of otherwise effective therapies. ..

..Moreover, it will provide an ideal experimental platform for numerous grants that are currently under review. ..

..Aim 4: To enhance the education/training of fellows/practitioners engaged in CVD disparities research/practice and promote partnerships that enhance cardiovascular health within ethnic communities. ..

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..The ability to decrease mortality and morbidity in ACS patients would benefit public health efforts, particularly efforts to improve the health of older persons, who are more prone to coronary events. ..

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..Finally, the overrepresentation of ethnic minority groups in MESA will allow for testing of interactions with ethnicity. We are unaware of any other population-based study adequate to study the stated aims. ..

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