diagnostic techniques and procedures

Summary

Summary: Methods, procedures, and tests performed to diagnose disease, disordered function, or disability.

Top Publications

  1. ncbi Resampling dependent concordance correlation coefficients
    John M Williamson
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    J Biopharm Stat 17:685-96. 2007
  2. ncbi Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews
    Johannes B Reitsma
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    J Clin Epidemiol 58:982-90. 2005
  3. pmc Comparative accuracy: assessing new tests against existing diagnostic pathways
    Patrick M Bossuyt
    Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, University of Amsterdam, Amsterdam 1100 DE, Netherlands
    BMJ 332:1089-92. 2006
  4. ncbi The binomial distribution of meta-analysis was preferred to model within-study variability
    Taye H Hamza
    Department of Epidemiology and Biostatistics, Erasmus MC Erasmus University Medical Center, Rotterdam, The Netherlands
    J Clin Epidemiol 61:41-51. 2008
  5. ncbi Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Ann Intern Med 138:40-4. 2003
  6. ncbi The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Ann Intern Med 138:W1-12. 2003
  7. ncbi The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center University of Amsterdam, 1100 DE Amsterdam, The Netherlands
    Clin Chem 49:7-18. 2003
  8. ncbi Reducing the burden of childhood malaria in Africa: the role of improved
    Maria E Rafael
    RAND Corporation, 1776 Main Street, PO Box 2138, Santa Monica, California 90401 2138, USA
    Nature 444:39-48. 2006
  9. ncbi Diagnostic yield of tuberculosis using sputum induction in HIV-positive patients before antiretroviral therapy
    S D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 16:1354-7. 2012
  10. pmc Misguided efforts and future challenges for research on "diagnostic tests"
    A R Feinstein
    Yale University School of Medicine, New Haven, USA
    J Epidemiol Community Health 56:330-2. 2002

Research Grants

  1. Considerations of covariates in biomarker studies
    Margaret S Pepe; Fiscal Year: 2010
  2. Reducing Transmission of Influenza by Face Masks
    ARNOLD MONTO; Fiscal Year: 2008
  3. Assessing Treatment-Related Harms in Prostate Cancer
    H Welch; Fiscal Year: 2007
  4. Oral-Based Diagnostics
    Daniel Malamud; Fiscal Year: 2006
  5. KALLIKREINS AS DIAGNOSTIC MARKERS OF OVARIAN CARCINOMA
    Eleftherios Diamandis; Fiscal Year: 2008
  6. Pain and drug abuse in HIV: Impact on health services
    JENNIE TSAO; Fiscal Year: 2005
  7. OPTIMIZING SOFTCOPY DISPLAYS FOR DIGITAL MAMMOGRAPHY
    Elizabeth Krupinski; Fiscal Year: 2003
  8. SUBMANDIBULAR SALIVARY PROTEINS SPECIFICALLY INHIBIT HIV
    Daniel Malamud; Fiscal Year: 2001
  9. CANCER CHEMOPREVENTION--ROLE OF INFECTION/IMMUNITY
    Charles Loprinzi; Fiscal Year: 2003
  10. GENETIC EPIDEMIOLOGY OF AGING IN A MULTIETHNIC COMMUNITY
    Richard Mayeux; Fiscal Year: 2002

Detail Information

Publications217 found, 100 shown here

  1. ncbi Resampling dependent concordance correlation coefficients
    John M Williamson
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    J Biopharm Stat 17:685-96. 2007
    ..Simulation results indicate that inference based on the bootstrap is valid, although type-I error rates are inflated for small sample sizes ( approximately 30). For illustration we analyze data from a carotid stenosis screening study...
  2. ncbi Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews
    Johannes B Reitsma
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    J Clin Epidemiol 58:982-90. 2005
    ..Studies of diagnostic accuracy most often report pairs of sensitivity and specificity. We demonstrate the advantage of using bivariate meta-regression models to analyze such data...
  3. pmc Comparative accuracy: assessing new tests against existing diagnostic pathways
    Patrick M Bossuyt
    Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, University of Amsterdam, Amsterdam 1100 DE, Netherlands
    BMJ 332:1089-92. 2006
  4. ncbi The binomial distribution of meta-analysis was preferred to model within-study variability
    Taye H Hamza
    Department of Epidemiology and Biostatistics, Erasmus MC Erasmus University Medical Center, Rotterdam, The Netherlands
    J Clin Epidemiol 61:41-51. 2008
    ..This method can easily be performed in standard statistical packages. We investigate the performance of the standard method and the alternative approach...
  5. ncbi Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Ann Intern Med 138:40-4. 2003
    ..To comprehend the results of diagnostic accuracy studies, readers must understand the design, conduct, analysis, and results of such studies. That goal can be achieved only through complete transparency from authors...
  6. ncbi The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Ann Intern Med 138:W1-12. 2003
    ..Complete and informative reporting can only lead to better decisions in health care...
  7. ncbi The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center University of Amsterdam, 1100 DE Amsterdam, The Netherlands
    Clin Chem 49:7-18. 2003
    ..Complete and informative reporting can only lead to better decisions in healthcare...
  8. ncbi Reducing the burden of childhood malaria in Africa: the role of improved
    Maria E Rafael
    RAND Corporation, 1776 Main Street, PO Box 2138, Santa Monica, California 90401 2138, USA
    Nature 444:39-48. 2006
  9. ncbi Diagnostic yield of tuberculosis using sputum induction in HIV-positive patients before antiretroviral therapy
    S D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 16:1354-7. 2012
    ..8-18.8). Spontaneously expectorated spot samples yielded 79.8% of all culture-positive TB diagnoses. The incremental yield from those needing an induced first sample was 5.3% and the yield from induced second samples was 14.9%...
  10. pmc Misguided efforts and future challenges for research on "diagnostic tests"
    A R Feinstein
    Yale University School of Medicine, New Haven, USA
    J Epidemiol Community Health 56:330-2. 2002
  11. ncbi Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Fam Pract 21:4-10. 2004
    ..Our aim was to improve the accuracy and completeness of reporting of studies of diagnostic accuracy in order to allow readers to assess the potential for bias in a study and to evaluate the generalizability of its results...
  12. ncbi Sources of variation and bias in studies of diagnostic accuracy: a systematic review
    Penny Whiting
    University of York, York, United Kingdom
    Ann Intern Med 140:189-202. 2004
    ..Studies of diagnostic accuracy are subject to different sources of bias and variation than studies that evaluate the effectiveness of an intervention. Little is known about the effects of these sources of bias and variation...
  13. pmc Conducting systematic reviews of diagnostic studies: didactic guidelines
    Walter L Deville
    Institute for Research in Extramural Medicine EMGO Institute, VU University Medical Centre, Amsterdam, The Netherlands
    BMC Med Res Methodol 2:9. 2002
    ..Although guidelines for critical appraisal of diagnostic research and meta-analyses have already been published, these may be difficult to understand for clinical researchers or do not provide enough detailed information...
  14. ncbi Bivariate meta-analysis of sensitivity and specificity with sparse data: a generalized linear mixed model approach
    Haitao Chu
    J Clin Epidemiol 59:1331-2; author reply 1332-3. 2006
  15. ncbi Interpreting diagnostic test accuracy studies
    Patrick M M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Semin Hematol 45:189-95. 2008
    ..We discuss the relativity of the claim that likelihood ratios are a superior way of expressing diagnostic accuracy, and defend the use of the sometimes downgraded sensitivity and specificity...
  16. pmc Diagnostic tests 4: likelihood ratios
    Jonathan J Deeks
    Screening and Test Evaluation Program, School of Public Health, University of Sydney, NSW 2006, Australia
    BMJ 329:168-9. 2004
  17. pmc EMBASE search strategies for identifying methodologically sound diagnostic studies for use by clinicians and researchers
    Nancy L Wilczynski
    Health Information Research Unit, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, L8N 3Z5 Canada
    BMC Med 3:7. 2005
    ..The objective of this study was to develop search strategies that optimize the retrieval of methodologically sound diagnostic studies from EMBASE for use by clinicians...
  18. ncbi When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we need randomized trials?
    Sarah J Lord
    National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, Sydney, Camperdown, NSW, Australia
    Ann Intern Med 144:850-5. 2006
    ....
  19. pmc Communicating accuracy of tests to general practitioners: a controlled study
    Johann Steurer
    Horten Zentrum für praxisorientierte Forschung und Wissenstransfer, Universitatsspital Zurich, Bolleystrasse 40, Postfach Nord, CH 8091 Zurich, Switzerland
    BMJ 324:824-6. 2002
    ..To assess the extent to which different forms of summarising diagnostic test information influence general practitioners' ability to estimate disease probabilities...
  20. pmc Cost implications of improving malaria diagnosis: findings from north-eastern Tanzania
    Jacklin F Mosha
    National Institute for Medical Research, Mwanza, Tanzania
    PLoS ONE 5:e8707. 2010
    ..This paper attempts to estimate the rates of over diagnosis of malaria among children attending dispensaries in rural Tanzania and examines the potential cost implications of improving the quality of diagnosis...
  21. ncbi Associating explanatory variables with summary receiver operating characteristic curves in diagnostic meta-analysis
    Taye Hussein Hamza
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    J Clin Epidemiol 62:1284-91. 2009
    ....
  22. ncbi QUADOMICS: an adaptation of the Quality Assessment of Diagnostic Accuracy Assessment (QUADAS) for the evaluation of the methodological quality of studies on the diagnostic accuracy of '-omics'-based technologies
    Blanca Lumbreras
    Public Health Department, Miguel Hernandez University, Alicante, Spain
    Clin Biochem 41:1316-25. 2008
    ..To adapt the Quality Assessment of Diagnostic Accuracy Assessment (QUADAS) to the particular methodological challenges posed by research on '-omics'-based diagnostic tests...
  23. ncbi Challenges in systematic reviews of diagnostic technologies
    Athina Tatsioni
    Tufts New England Medical Center Evidence based Practice Center, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 142:1048-55. 2005
    ....
  24. ncbi There is nothing staid about STARD: progress in the reporting of diagnostic accuracy studies
    Karen C Johnston
    Neurology 67:740-1. 2006
  25. ncbi Three approaches to regression analysis of receiver operating characteristic curves for continuous test results
    M S Pepe
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, Washington 98104, USA
    Biometrics 54:124-35. 1998
    ..It is hoped that the presentation in this paper will both encourage the use of regression analysis for evaluating diagnostic tests and help guide the choice of the most appropriate regression analysis approach in applications...
  26. pmc The predictive receiver operating characteristic curve for the joint assessment of the positive and negative predictive values
    Shang Ying Shiu
    Institute of Statistical Science, Academia Sinica, Taipei 115, Taiwan, Republic of China
    Philos Trans A Math Phys Eng Sci 366:2313-33. 2008
    ..We also formulate and discuss regression models for the estimation of the effects of covariates...
  27. pmc Evidence of bias and variation in diagnostic accuracy studies
    Anne W S Rutjes
    Deptartment of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    CMAJ 174:469-76. 2006
    ..We sought to determine and compare the direction and magnitude of the effects of a number of potential sources of bias and variation in studies on estimates of diagnostic accuracy...
  28. ncbi Spectrum bias or spectrum effect? Subgroup variation in diagnostic test evaluation
    Stephanie A Mulherin
    University of North Carolina at Chapel Hill, Department of Epidemiology, Chapel Hill, NC 27599 7435, USA
    Ann Intern Med 137:598-602. 2002
    ..Furthermore, clinicians should consider study samples carefully to determine whether results are generalizable to their specific patient population...
  29. ncbi Sensitivity and specificity should be de-emphasized in diagnostic accuracy studies
    Karel G M Moons
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 80035, 3508 TA Utrecht, The Netherlands
    Acad Radiol 10:670-2. 2003
  30. ncbi Empirical Bayes estimates generated in a hierarchical summary ROC analysis agreed closely with those of a full Bayesian analysis
    Petra Macaskill
    Screening and Test Evaluation Program, School of Public Health, University of Sydney, NSW 2006, Australia
    J Clin Epidemiol 57:925-32. 2004
    ..The objective of this report is to show how the model may be fitted using the SAS procedure NLMIXED and to compare the results to the fully Bayesian analysis using an example...
  31. ncbi Spectrum bias: a quantitative and graphical analysis of the variability of medical diagnostic test performance
    Catherine Goehring
    Clinical Epidemiology Division, University Hospital, Geneva, Switzerland
    Stat Med 23:125-35. 2004
    ..We conclude that spectrum effect is more common than spectrum bias and that clinical decisions are affected only under certain conditions...
  32. ncbi Modified exact sample size for a binomial proportion with special emphasis on diagnostic test parameter estimation
    Geoffrey T Fosgate
    Department of Veterinary Anatomy and Public Health, College of Veterinary Medicine, Texas A and M University, College Station, 77843 4458, USA
    Stat Med 24:2857-66. 2005
    ..This algorithm resulted in sample sizes that achieved the appropriate confidence interval width even in situations when normal approximation methods performed poorly...
  33. ncbi Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative
    Patrick M Bossuyt
    Academic Medical Center, Department of Clinical Epidemiology, University of Amsterdam, Amsterdam, The Netherlands
    Clin Chem Lab Med 41:68-73. 2003
    ..To improve the accuracy and completeness of reporting of studies of diagnostic accuracy, to allow readers to assess the potential for bias in the study and to evaluate its generalisability...
  34. ncbi Assessing observer agreement in studies involving replicated binary observations
    Michael Haber
    Department of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
    J Biopharm Stat 17:757-66. 2007
    ..The reliability of the estimation method is examined via a simulation study. Data from a study aimed at determining the validity of diagnosis of breast cancer based on mammograms is used to illustrate the new concepts and methods...
  35. ncbi A class of repeated measures concordance correlation coefficients
    Tonya S King
    Pennsylvania State University College of Medicine, Pennsylvania 17033, USA
    J Biopharm Stat 17:653-72. 2007
    ....
  36. ncbi General radiologists' diagnostic accuracy: incomplete presentation of data casts doubt on study's conclusions
    Marilyn T Zivian
    AJR Am J Roentgenol 184:697-9. 2005
  37. ncbi [Evaluation of diagnostic methods]
    F Doyon
    Institut Gustave Roussy, , 39, rue Camille Desmoulins, 94805 Villejuif
    J Radiol 82:117-25. 2001
    ..CONCLUSION: The tools required to evaluate diagnostic tests rigorously are available and simple. They should be used more often...
  38. ncbi Diagnostic accuracy of the Triage D-dimer test for exclusion of venous thromboembolism in outpatients
    Timothy Ghys
    Department of Hematology, Universitair Ziekenhuis Brussel, Laarbeeklaan 101, B 1090 Brussels, Belgium
    Thromb Res 121:735-41. 2008
    ..We evaluated the diagnostic performance of the Triage D-dimer test, a new fast quantitative point-of-care whole blood D-dimer assay and compared it with the Vidas D-dimer assay...
  39. ncbi Toward complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Acad Radiol 10:664-9. 2003
    ..The authors sought to develop guidelines for improving the accuracy and completeness of reporting of studies of diagnostic accuracy in order to allow readers better to assess the validity and generalizability of study results...
  40. ncbi Measuring diagnostic and predictive accuracy in disease management: an introduction to receiver operating characteristic (ROC) analysis
    Ariel Linden
    Linden Consulting Group, Portland, OR 97124, USA
    J Eval Clin Pract 12:132-9. 2006
    ..Therefore the implementation of ROC as an evaluation tool should be strongly considered in the various phases of a DM programme...
  41. ncbi Assessing individual agreement
    Huiman X Barnhart
    Department of Biostatistics and Bioinformatics, Duke Clinical Research Institute, Duke University, Durham, North Carolina 27715, USA
    J Biopharm Stat 17:697-719. 2007
    ..A method of moments is used for estimation, where one can utilize output from ANOVA models. The nonparametric and bootstrap approaches are used for inference. Five examples are used for illustration...
  42. ncbi Comparison of concordance correlation coefficient and coefficient of individual agreement in assessing agreement
    Huiman X Barnhart
    Department of Biostatistics and Bioinformatics, Duke Clinical Research Institute, Duke University, Durham, North Carolina 27715, USA
    J Biopharm Stat 17:721-38. 2007
    ..The relationship between CCC and CIA as well as the impact of between-subject variability are presented algebraically and graphically. Several examples are presented to explain the interpretation of the CCC and CIA values...
  43. ncbi Medical errors as a result of specialization
    Ahmad Hashem
    Healthcare Industry Solutions Group, Microsoft Corporation, One Microsoft Way, Redmond, WA 98052, USA
    J Biomed Inform 36:61-9. 2003
    ..Specialists generate more diagnostic hypotheses within their domain than outside, and assign higher probabilities to diagnoses within that domain...
  44. ncbi Regression models for method comparison data
    Graham Dunn
    Biostatistics Group, Division of Epidemiology and Health Sciences, University of Manchester, Manchester, UK
    J Biopharm Stat 17:739-56. 2007
    ..Large samples are frequently needed and two-phase sampling methods are introduced to improve the efficiency of the IV estimators...
  45. ncbi Application of summary receiver operating characteristics (sROC) analysis to diagnostic clinical testing
    A S Rosman
    Section of Gastroenterology and Medicine Program, James J Peters VAMC, Bronx, NY 10468, USA
    Adv Med Sci 52:76-82. 2007
    ..Statistical formulas can compare these values from different diagnostic tests. With the introduction of sROC software and better understanding of this method, the application of sROC analysis should continue to increase...
  46. ncbi A practical approach to the diagnosis of growth hormone (GH) deficiency in patients transitioning to adulthood using GH stimulation testing
    Dennis M Styne
    Department of Pediatric Endocrinology, University of California Davis School of Medicine, Sacramento, CA 95817, USA
    J Pediatr Endocrinol Metab 16:637-43. 2003
    ..Thus the choice of testing methods impacts the diagnosis of GHD in transition patients...
  47. ncbi Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Standards for Reporting of Diagnostic Accuracy
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center University of Amsterdam, 1100 DE Amsterdam, The Netherlands
    Clin Chem 49:1-6. 2003
    ..To comprehend the results of diagnostic accuracy studies, readers must understand the design, conduct, analysis, and results of such studies. That goal can be achieved only through complete transparency from authors...
  48. ncbi Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, 1100 DE Amsterdam, The Netherlands
    Clin Biochem 36:2-7. 2003
    ..To improve the accuracy and completeness of reporting of studies of diagnostic accuracy in order to allow readers to assess the potential for bias in the study and to evaluate its generalisability...
  49. ncbi Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center University of Amsterdam, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    AJR Am J Roentgenol 181:51-5. 2003
    ..To improve the accuracy and completeness of reporting of studies of diagnostic accuracy in order to allow readers to assess the potential for bias in a study and to evaluate the generalisability of its results...
  50. pmc Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, Netherlands
    BMJ 326:41-4. 2003
    ..To improve the accuracy and completeness of reporting of studies of diagnostic accuracy, to allow readers to assess the potential for bias in a study, and to evaluate a study's generalisability...
  51. ncbi Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative
    Patrick M Bossuyt
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, The Netherlands
    Radiology 226:24-8. 2003
    ..To improve the accuracy and completeness of reporting of studies of diagnostic accuracy, to allow readers to assess the potential for bias in the study and to evaluate its generalisability...
  52. ncbi Toward complete and accurate reporting of studies of diagnostic accuracy. The STARD initiative
    Patrick M Bossuyt
    Dept of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Am J Clin Pathol 119:18-22. 2003
    ..If medical journals adopt the checklist and the flow diagram, the quality of reporting of studies of diagnostic accuracy should improve, to the advantage of clinicians, researchers, reviewers, journals, and the public...
  53. ncbi [Reporting studies of diagnostic accuracy according to a standard method; the Standards for Reporting of Diagnostic Accuracy (STARD)]
    P M Bossuyt
    Academisch Medisch Centrum Universiteit van Amsterdam, Afd Klinische Epidemiologie en Biostatistiek, Postbus 22 700, 1100 DE Amsterdam
    Ned Tijdschr Geneeskd 147:336-40. 2003
    ..Use of the checklist and flow diagram will improve the quality of reports produced, to the advantage of clinicians, researchers, reviewers, journal editors and other interested parties...
  54. ncbi Evidence-based laboratory medicine: addressing bias, generalisability and applicability in studies on diagnostic accuracy. The STARD initiative
    Matthew McQueen
    Clin Chem Lab Med 41:1. 2003
  55. ncbi Reporting studies of diagnostic accuracy: the STARD initiative
    Roger Jones
    Fam Pract 21:3. 2004
  56. ncbi Do we need a checklist for reporting the results of diagnostic test evaluations? The STARD proposal
    Constantine Gatsonis
    Acad Radiol 10:599-600. 2003
  57. ncbi A grey zone for quantitative diagnostic and screening tests
    Joel Coste
    Département de Biostatistique, Pavillon Saint Jacques, Hopital Cochin, 27 rue du Faubourg Saint Jacques, 75674 Paris Cedex 14, France
    Int J Epidemiol 32:304-13. 2003
    ..This partition intentionally includes a grey zone between positive and negative conclusions...
  58. ncbi A fast, simple, and inexpensive method to collect exhaled breath condensate for pH determination
    Philippe Prince
    Unité de Recherche en Pneumologie, Centre de Recherche de l Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Quebec, Canada
    Ann Allergy Asthma Immunol 97:622-7. 2006
    ..Exhaled breath condensate (EBC) analysis is a noninvasive method for assessing lower airway inflammation. Various methods of collecting EBC have been described. However, they are often time-consuming or involve expensive equipment...
  59. ncbi Comparative validity of three screening questionnaires for DSM-IV depressive disorders and physicians' diagnoses
    Bernd Löwe
    Department of General Internal and Psychosomatic Medicine, University of Heidelberg, Medical Hospital, Bergheimer Strasse 58, D 69115, Heidelberg, Germany
    J Affect Disord 78:131-40. 2004
    ....
  60. ncbi Automated analytical microarrays: a critical review
    Michael Seidel
    Chair for Analytical Chemistry and Institute of Hydrochemistry, Technische Universitat Munchen, Marchioninistrasse 17, 81377, Munchen, Germany
    Anal Bioanal Chem 391:1521-44. 2008
    ..This review gives an overview of the current research on microarrays with the focus on automated systems and quantitative multiplexed applications...
  61. ncbi Results of diagnostic accuracy studies are not always validated
    Ann Van den Bruel
    Department of General Practice ACHG, Katholieke Universiteit Leuven, Kapucijnenvoer 33, Blok J, 3000 Leuven, Belgium
    J Clin Epidemiol 59:559-66. 2006
    ..Here we describe whether diagnostic research is validated, which technique is used, and to what extent the validation study results differ from the original...
  62. ncbi The sensitivity of the Malay version of Brief Manual of Sexual Function Inventory in assessing erectile dysfunction secondary to benign prostatic hyperplasia
    K F Quek
    Health Research Development Unit, University Malaya Medical Centre, 50603 Kuala Lumpur
    Med J Malaysia 58:356-64. 2003
    ..The Mal-BMSFI is a suitable, reliable, valid and sensitive to clinical change in the Malaysian population...
  63. ncbi Agreement between methods of measurement with multiple observations per individual
    J Martin Bland
    Department of Health Sciences, University of York, York, UK
    J Biopharm Stat 17:571-82. 2007
    ..In this paper we describe methods for analysing such clustered observations, both when the underlying quantity is assumed to be changing and when it is not...
  64. ncbi Protein profiling as a diagnostic tool in clinical chemistry: a review
    Judith A P Bons
    Department of Clinical Chemistry, University Hospital Maastricht, Maastricht, The Netherlands
    Clin Chem Lab Med 43:1281-90. 2005
    ..Further progress in protein profiling as a diagnostic tool requires a more comprehensive description of technical details in all future studies...
  65. ncbi Diagnostic accuracy of flow rate testing in urology
    H R H Patel
    Institute of Urology and Nephrology, University College London Medical School, London, UK
    BJU Int 92:58-63. 2003
    ..To highlight the importance of methodological standards in diagnostic testing in urology, by reviewing the extent of compliance with these standards in reports of published evaluations...
  66. ncbi [Using characteristic numbers to estimate the usefulness of laboratory tests for diagnosis]
    Matti Uhari
    Oulun yliopiston lastentautien klinikka PL 5000, 90014 Oulun yliopisto
    Duodecim 120:935-41. 2004
  67. ncbi [Recent advance in diagnostic telepathology]
    Xin xia Li
    Zhonghua Bing Li Xue Za Zhi 35:176-8. 2006
  68. ncbi Assessment of the accuracy of diagnostic tests: the cross-sectional study
    J A Knottnerus
    University of Maastricht, Netherlands School of Primary Care Research, Post Office Box 616, 6200 MD Maastricht, The Netherlands
    J Clin Epidemiol 56:1118-28. 2003
    ..Also, systematic reviews and meta-analysis have a role. To enable readers of diagnostic research reports to evaluate whether methodological key issues were addressed, authors are advised to follow the STARD guidelines...
  69. ncbi A high performance liquid chromatographic method for the measurement of total carnitine in human plasma and urine
    Christopher J McEntyre
    Biochemistry Unit, Canterbury Health Laboratories, P O Box 151, Christchurch, New Zealand
    Clin Chim Acta 344:123-30. 2004
    ..Advantages of this method include good precision, accuracy and linearity, the use of fluorescence to gain sensitivity, the small sample volume required and a relatively low sample preparation time...
  70. pmc The use of "overall accuracy" to evaluate the validity of screening or diagnostic tests
    Anthony J Alberg
    Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Gen Intern Med 19:460-5. 2004
    ..We assessed the value of overall accuracy in studies of test validity, a topic that has not received adequate emphasis in the clinical literature...
  71. ncbi Diagnostic accuracy of clinical tests for the different degrees of subacromial impingement syndrome
    Hyung Bin Park
    Department of Orthopaedic Surgery, College of Medicine, Gyeong Sang National University, 90 Chilamdong 660 751, Jinju, South Korea
    J Bone Joint Surg Am 87:1446-55. 2005
    ..The hypothesis of this study was that the degree of severity of rotator cuff disease affects the diagnostic values of the commonly used clinical tests...
  72. ncbi New methods in the assessment of diagnostic procedures
    Jos Kleijnen
    Kleijnen Systematic Reviews Limited, York, England
    Z Arztl Fortbild Qualitatssich 100:519-25. 2006
    ..Diagnostic research needs careful consideration of the clinical situation, and should take into account that diagnosis is a multivariable process. Various study designs to evaluate diagnostic procedures are presented...
  73. ncbi A systematic review of the clinical diagnostic tests for carpal tunnel syndrome
    N Massy Westropp
    School of Occupational Therapy, University of South Australia, North Terrace, Adelaide, South Australia
    J Hand Surg Am 25:120-7. 2000
    ..Many reports do not include methodology, which makes the results difficult to reproduce and to apply to other populations. (J Hand Surg 2000; 25A:120-127...
  74. ncbi [Diagnostics: new methodological initiatives]
    Erik Magid
    Amager Hospital, Klinisk Biokemisk Afdeling
    Ugeskr Laeger 166:1664-6. 2004
  75. ncbi Accuracy of diagnostic tests read with and without clinical information: a systematic review
    Clement T Loy
    Screening and Test Evaluation Program, School of Public Health, University of Sydney, Sydney, Australia
    JAMA 292:1602-9. 2004
    ..Although it is common practice to read tests with clinical information, whether this improves or decreases the accuracy of test reading is uncertain...
  76. ncbi The STARD initiative: a possible link to diagnostic accuracy and reduction in medical error
    M J McQueen
    Ann Clin Biochem 40:307-8. 2003
  77. ncbi User's guide to the surgical literature: how to use an article about a diagnostic test
    Mohit Bhandari
    Department of Clinical Epidemiology and Biostatistics, McMaster University Health Sciences Center, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada
    J Bone Joint Surg Am 85:1133-40. 2003
  78. ncbi Idiopathic infantile asymmetry, proposal of a measurement scale
    Heike Philippi
    University Children s Hospital, Johannes Gutenberg University, Langenbeckstr 1 55101 Mainz, Germany
    Early Hum Dev 80:79-90. 2004
    ..Statistical analysis indicated good reliability and consistency of the testing method with an intraclass correlation coefficient of 91.5% (Cronbach alpha 0.84)...
  79. ncbi Interpretation of diagnostic tests
    R H Fletcher
    Harvard Medical School, Department of Ambulatory Care and Prevention, Boston, MA 02215, USA robert
    Indian J Pediatr 67:49-53. 2000
    ..Describing test performance in terms of likelihood ratios facilitates this process. Readers should be able to critique published studies of diagnostic tests which are still far from perfect...
  80. pmc Synthesis of polyacrylamides N-substituted with PNA-like oligonucleotide mimics for molecular diagnostic applications
    V A Efimov
    Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, ul Miklukho Maklaya 16 10, Moscow 117871, Russia
    Nucleic Acids Res 27:4416-26. 1999
    ....
  81. pmc Proceedings of the 2012 National Toxicology Program Satellite Symposium
    Susan A Elmore
    National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 41:151-80. 2013
    ....
  82. ncbi The declining number and variety of procedures done by general internists: a resurvey of members of the American College of Physicians
    Robert S Wigton
    University of Nebraska Medical Center College of Medicine, Omaha, Nebraska 68198 4285, USA
    Ann Intern Med 146:355-60. 2007
    ..Since then, changes in the practice of medicine, regulatory requirements, and availability of subspecialists may have affected the number and type of procedures done by internists...
  83. ncbi Typical Friedreich's ataxia without GAA expansions and GAA expansion without typical Friedreich's ataxia
    D J McCabe
    Department of Neurology, Adelaide and Meath Hospital, Tallaght, Dublin, Ireland
    J Neurol 247:346-55. 2000
    ..Although molecular genetic analysis now plays an essential role in diagnosis and classification, patients with a typical FA phenotype without any identifiable cause for their ataxia exist...
  84. ncbi The fibromyalgia tender points: use them or lose them? A brief review of the controversy
    Manfred Harth
    J Rheumatol 34:914-22. 2007
  85. ncbi Diagnosis of pulmonary embolism in outpatients by sequential noninvasive tools
    A Perrier
    Division of Angiology and Hemostasis, University Hospital, Geneva, Switzerland
    Semin Thromb Hemost 27:25-32. 2001
    ..Finally, spiral computed tomography (CT) seems promising and might modify the diagnostic work-up of PE in the near future. However, it is insufficiently validated, and its place in a rational diagnostic algorithm is not defined...
  86. ncbi Prospective evaluation of propofol anesthesia in the pediatric intensive care unit for elective oncology procedures in ambulatory and hospitalized children
    J H Hertzog
    Department of Pediatrics, Georgetown University Medical Center, Washington, DC, USA
    Pediatrics 106:742-7. 2000
    ..To evaluate our experience with propofol anesthesia delivered by pediatric intensivists in the pediatric intensive care unit (PICU) to facilitate elective oncology procedures in children performed by pediatric oncologists...
  87. ncbi [Is systemic diagnosis possible?]
    Anna Siewierska
    Klinika Psychiatrii Dzieci i Młodziezy IPiN w Warszawie
    Psychiatr Pol 42:17-24. 2008
    ..The authors also stress the crucial effect of the constructivism and social constructionism on the process of the systemic diagnosis...
  88. ncbi Customizable wireless remote control for collaborative medical diagnosis and teaching
    Rajasvaran Logeswaran
    Global School of Media, Soongsil University, Seoul 156 743, Korea
    J Med Syst 33:389-98. 2009
    ..Description of the implementation ideas and results achieved in the development of the firmware and hardware for such a technological tool for use in improving collaborative medical diagnosis and teaching are presented in this article...
  89. ncbi Innovations in optical microfluidic technologies for point-of-care diagnostics
    Frank B Myers
    Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, CA 94720, USA
    Lab Chip 8:2015-31. 2008
    ..We also examine several emerging detection paradigms involving nanoengineered materials which do not suffer from the same miniaturization disadvantages as conventional measurements...
  90. ncbi Tissue arrays as fiducial markers for section alignment in 3-D reconstruction technology
    G Bussolati
    Department of Biomedical Sciences and Human Oncology, University of Turin, Turin, 10126, Italy
    J Cell Mol Med 9:438-45. 2005
    ..This original methodology of incorporating Tissue Arrays into paraffin blocks as fiducial markers for three-dimensional reconstruction has a potential impact on histology for research purposes and diagnostic applications...
  91. ncbi LVI review
    A C Talbot
    Vet Rec 153:340. 2003
  92. ncbi Robotics present huge opportunities
    Nicholas Marshall
    Health Estate 62:21-3. 2008
    ..Glimpses of micro-engineering excellence needed for new generations of operating theatre and diagnostic department robotics were provided at a London conference. Nicholas Marshall reports...
  93. ncbi Evaluation of Ves-Matic Cube 200--an automated system for the measurement of the erythrocyte sedimentation rate
    E Perovic
    Department of Laboratory Diagnostics, General Hospital Zadar, Zadar, Croatia
    Int J Lab Hematol 32:88-94. 2010
    ..48 mm/h; 95% CI: -16.580 to -8.390 mm/h, respectively). The obtained results suggest that the Ves-Matic Cube 200 automated analyzer is reliable system for the measurement of ESR in clinical laboratories...
  94. ncbi An evaluation of three measures of intracranial compliance in traumatic brain injury patients
    Tim Howells
    Section of Neurosurgery, Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Intensive Care Med 38:1061-8. 2012
    ..To compare intracranial pressure (ICP) amplitude, ICP slope, and the correlation of ICP amplitude and ICP mean (RAP index) as measures of compliance in a cohort of traumatic brain injury (TBI) patients...
  95. ncbi [Evaluation of serum cytokines in small cell lung cancer and its clinical significance]
    Xianfeng LU
    Cancer Center and Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, China
    Zhongguo Fei Ai Za Zhi 15:11-6. 2012
    ..The current research investigates the different changes of cytockines and searches for potential biomarkers to improve the situation of the early diagnosis of SCLC...
  96. ncbi Artificial neural networks for diagnosis and prognosis in prostate cancer
    Guido Schwarzer
    Institute of Medical Biometry and Medical Informatics, University of Freiburg, Germany
    Semin Urol Oncol 20:89-95. 2002
    ..It is concluded that there is so far no evidence that the application of ANNs provide real progress in the field of diagnosis and prognosis in prostate cancer...
  97. ncbi Vertical instability in spondylolisthesis: a traction radiographic assessment technique and the principle of management
    Keith D K Luk
    Duchess of Kent Children s Hospital, The University of Hong Kong, Hong Kong hrmoldk hkucc hku hk
    Spine (Phila Pa 1976) 28:819-27. 2003
    ..These radiographs were taken in the neutral, flexion, and extension positions for both erect and recumbent postures, and also in the prone and supine positions with traction applied via a traction table...
  98. ncbi Evaluation of the overhead athlete: Examination and ancillary testing
    Benjamin D Rubin
    Arthroscopy 19:42-6. 2003
  99. ncbi Determinants of pathology in light-irradiated cells
    Michael S Sinyakov
    Bar Ilan University, Ramat Gan, Israel
    Photochem Photobiol 86:123-30. 2010
    ....
  100. pmc The opinion of clinical staff regarding painfulness of procedures in pediatric hematology-oncology: an Italian survey
    Chiara Po'
    Pediatric Pain and Palliative Care Service, Department of Pediatrics, University of Padua, Italy
    Ital J Pediatr 37:27. 2011
    ..Aim of this study was to evaluate professionals' beliefs about painfulness of invasive procedures repeatedly performed in Pediatric Hemato-Oncology Units...
  101. pmc Infraspinatus scapular retraction test: a reliable and practical method to assess infraspinatus strength in overhead athletes with scapular dyskinesis
    Giovanni Merolla
    Unit of Shoulder and Elbow Surgery, D Cervesi Hospital, L V Beethowen 46, 47841, Cattolica, RN, Italy
    J Orthop Traumatol 11:105-10. 2010
    ....

Research Grants54

  1. Considerations of covariates in biomarker studies
    Margaret S Pepe; Fiscal Year: 2010
    ..Programs written in Stata will be made available through the Stata archive, the EDRN and through a 'Diagnostics and Biomarkers Statistical Center'web site. ..
  2. Reducing Transmission of Influenza by Face Masks
    ARNOLD MONTO; Fiscal Year: 2008
    ..Such a reduction could have a major public health impact during a pandemic. In the second year, the study can be expanded or modified based on findings in the first. ..
  3. Assessing Treatment-Related Harms in Prostate Cancer
    H Welch; Fiscal Year: 2007
    ..The entire process will be repeated on a cohort of men who receive a transurethral resection of the prostate. ..
  4. Oral-Based Diagnostics
    Daniel Malamud; Fiscal Year: 2006
    ..This conference will focus on advances and new technologies in the oral diagnostics field and their utility for detection of health status. [unreadable] [unreadable] [unreadable]..
  5. KALLIKREINS AS DIAGNOSTIC MARKERS OF OVARIAN CARCINOMA
    Eleftherios Diamandis; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  6. Pain and drug abuse in HIV: Impact on health services
    JENNIE TSAO; Fiscal Year: 2005
    ..The proposed research agenda encompasses a set of analyses that will provide valuable insights into the health and well being of IDUs and drug dependent patients in care for HIV. ..
  7. OPTIMIZING SOFTCOPY DISPLAYS FOR DIGITAL MAMMOGRAPHY
    Elizabeth Krupinski; Fiscal Year: 2003
    ..The JND metrix model will then be used to systematically explore and optimize CRT design tradeoffs for current and future digital-mammography display systems. ..
  8. SUBMANDIBULAR SALIVARY PROTEINS SPECIFICALLY INHIBIT HIV
    Daniel Malamud; Fiscal Year: 2001
    ..3. To determine the mechanism by which salivary proteins inhibit HIV infectivity using in vitro models of oral infection. 4. To define the significance of anti-HIV proteins in saliva obtained from HIV-seropositive donors. ..
  9. CANCER CHEMOPREVENTION--ROLE OF INFECTION/IMMUNITY
    Charles Loprinzi; Fiscal Year: 2003
    ..abstract_text> ..
  10. GENETIC EPIDEMIOLOGY OF AGING IN A MULTIETHNIC COMMUNITY
    Richard Mayeux; Fiscal Year: 2002
    ....
  11. Non-steroidal anti-inflammatory use and miscarriage
    Katherine E Hartmann; Fiscal Year: 2010
    ....
  12. Cutaneous Gene Therapy with Ultrasound: DNA Vaccination
    Samir Mitragotri; Fiscal Year: 2006
    ..3. Using an in vitro model, Epiderm, and in vivo mouse model, assess safety of skin exposure to low-frequency ultrasound. ..
  13. Comparative Study of Influenza Vaccines in Adults
    ARNOLD MONTO; Fiscal Year: 2006
    ..Results will help to determine how the vaccine may be used as part of the strategy to combat influenza in varying situations. [unreadable] [unreadable]..
  14. Social Conversation Training Simulation for Adults with Autism Spectrum Disorder
    Dale Olsen; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  15. OPTIMIZING SOFTCOPY DISPLAYS FOR DIGITAL MAMMOGRAPHY
    Elizabeth Krupinski; Fiscal Year: 2002
    ..The JND metrix model will then be used to systematically explore and optimize CRT design tradeoffs for current and future digital-mammography display systems. ..
  16. EPIDEMIOLOGY OF DEMENTIA IN AN URBAN COMMUNITY
    Richard Mayeux; Fiscal Year: 2008
    ..The overall theme of this fourth renewal application is to identify reliable and valid antecedent biomarkers of AD and MCI and to extend these and other clinical parameters to the measurement of disease progression. ..
  17. Procoagulants in Aging CARDIA Participants
    David Green; Fiscal Year: 2009
    ....
  18. Vocational Rehabilitation Training Simulation for the Psychiatrically Disabled
    Dale Olsen; Fiscal Year: 2008
    ..Society benefits from regaining the productive potential of people who may otherwise be marginalized and from increasing the diversity of our nation's workforce. [unreadable] [unreadable] [unreadable]..
  19. Immune Thrombocytopenia and Low-Level Mercury Exposure
    Jodi Segal; Fiscal Year: 2006
    ..Segal with the necessary support for successful completion [unreadable] [unreadable] [unreadable]..
  20. Optimized Compression for Telepathology Virtual Slides
    Elizabeth Krupinski; Fiscal Year: 2009
    ....
  21. Anti-HIV Activity of Lung SRCR (gp-340) in Saliva
    Daniel Malamud; Fiscal Year: 2005
    ..abstract_text> ..
  22. Prosodic Impairment and Speech Intelligibility in Perso*
    Kate Bunton; Fiscal Year: 2005
    ..Enhancing the F0 contour to include the peaks and valleys typical in normal speakers will decrease segment error rates. ..
  23. Conference--Medical Image Perception
    Elizabeth Krupinski; Fiscal Year: 2003
    ..This grant will be used to provide financial support for about 12 graduate students and residents, as well as logistic support for publicity and program printing. ..
  24. PROSPECTIVE INVESTIGATION OF PULMONARY EMBOLISM DX-II
    Paul Stein; Fiscal Year: 2003
    ..4) The team of investigators is strong, and has collaborated previously in successful research in PE. ..
  25. A Novel and Non-Invasive Method of Dermal Sampling
    Samir Mitragotri; Fiscal Year: 2003
    ..abstract_text> ..
  26. MIDCAREER INVESTIGATOR AWARD IN CEREBROVASCULAR RESEARCH
    Larry Goldstein; Fiscal Year: 2004
    ....
  27. GENETIC EPIDEMIOLOGY OF ALZHEIMERS DISEASE IN HISPANICS
    Richard Mayeux; Fiscal Year: 2003
    ..The ultimate goal of this project is to chromosomally localize genes that may increase the risk of AD among the Caribbean Hispanic ethnic group. ..
  28. A Microfluidic Diffusion Immunoassay
    Paul Yager; Fiscal Year: 2002
    ..abstract_text> ..
  29. Human Kallikrein 4 (hK4): A New Prostatic Biomarker?
    Eleftherios Diamandis; Fiscal Year: 2003
    ..If successful, our research will contribute to the development of new prostatic biomarkers and possibly, to better diagnosis which may lead to better clinical outcomes and reduced healthcare costs. ..
  30. Point Detection of Pathogens in Oral Samples via UPT
    Daniel Malamud; Fiscal Year: 2005
    ..We now present a plan to combine these separate analyses into a single system that can be used on-site to analyze up to 200 target analytes. ..
  31. A New Biomarker for Ovarian Cancer Detection
    Eleftherios Diamandis; Fiscal Year: 2003
    ..In this grant proposal, we describe further studies, which will examine in greater detail, the ability of a test for the amount of this protein in blood to correctly diagnose the presence of ovarian cancer. ..
  32. Consequences and Course of Uterine Fibroids in Pregnancy
    Katherine Hartmann; Fiscal Year: 2008
    ..By prospectively investigating fibroid characteristics and risk, this research has potential to inform care for many women with fibroids who are pregnant or planning pregnancy. ..
  33. MIPS XII Conference
    Elizabeth Krupinski; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  34. Prospective Investigation for Pulmonary Embolism Dx III
    Paul Stein; Fiscal Year: 2008
    ..abstract_text> ..
  35. Rapid parallel salivary immunoassays on a disposable
    Paul Yager; Fiscal Year: 2005
    ..Finally, a versatile combined system will be designed and tested that will allow monitoring of samples by the two methods simultaneously. ..
  36. Substance Abuse Diagnostic Clinical Interview Simulation
    Dale Olsen; Fiscal Year: 2008
    ..If successful, it will provide a tool to enable students to learn critical skills that will help them interact with and diagnose patients in a more accurate and efficient manner. [unreadable] [unreadable] [unreadable]..
  37. Interactive Multimedia Simulation to Train Motivational Interviewing Skills
    Dale Olsen; Fiscal Year: 2007
    ..The proposed research will produce an innovative new training tool with the potential to increase learning and retention of MI skills among clinicians, thereby benefiting their patients. [unreadable] [unreadable] [unreadable]..
  38. Bioinformatics for Protein Microarrays
    Richard Zangar; Fiscal Year: 2009
    ....
  39. AMPHETAMINE ENHANCED STROKE RECOVERY--BURKE SRCI GROUP
    Larry Goldstein; Fiscal Year: 2002
    ..However the treatment duration will be increased to a total of 10 sessions. ..
  40. Horizontal Basal Cells in the Adult Olfactory Epithelium
    AMY CLEVENGER; Fiscal Year: 2005
    ..Better understanding of the basal cell populations within the OE will also allow us to take new directions in the prevention and treatment of olfactory dysfunction. ..
  41. Medical Image Perception Society Confrence XI
    Elizabeth Krupinski; Fiscal Year: 2005
    ..abstract_text> ..
  42. New Methods for Evaluating Interobserver Agreement
    Michael Haber; Fiscal Year: 2006
    ..Existing and new agreement indices will be compared and linked. All the proposed methods will be applied to real data sets from the behavioral and biomedical sciences. [unreadable] [unreadable]..
  43. REGULATION OF XENOBIOTIC-METABOLIZING CYP3A
    Richard Zangar; Fiscal Year: 2002
    ....
  44. SUBTLE DISTURBANCES OF COBALAMIN STATUS
    Ralph Carmel; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  45. Organizational Factors in the Early Detection of HIV
    Oscar Grusky; Fiscal Year: 2005
    ....
  46. Improving Heart Failure Risk Stratification in the ED
    Alan B Storrow; Fiscal Year: 2010
    ..In collaboration with outcomes and effectiveness researchers, we plan to conduct further studies to test the efficacy of our risk model. ..
  47. Tissue Homogenizaton by Pressure Cycling Technology
    Feng Tao; Fiscal Year: 2003
    ..The successful development of the PCT homogenization technology will benefit molecular based analytical procedures in genomics, medical, forensic, agricultural, pharmaceutical, veterinary and clinical applications ..
  48. A Multiplex, Point-of-Care Test for Enteric Pathogens
    Bernhard Weigl; Fiscal Year: 2007
    ..abstract_text> ..
  49. A PCT Sample Preparation System for Proteomic Research and Clinical Diagnostics
    Feng Tao; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  50. Nucleic Acid Purification Using Pressure Cycling Technology
    Feng Tao; Fiscal Year: 2007
    ..If successful, this technology could be immediately employed in many fields of life sciences. [unreadable] [unreadable] [unreadable]..
  51. HOMOCYST(E)INE, OXIDATIVE STRESS, AND NITRIC OXIDE
    Joseph Loscalzo; Fiscal Year: 2004
    ..With these studies, we hope to gain insight into the molecular mechanisms of homocyst(e)ine-induced endothelial dysfunction and potential therapies for this common metabolic abnormality. ..
  52. A Microfluidic Diffusion Immunoassay
    Paul Yager; Fiscal Year: 2004
    ..abstract_text> ..
  53. GPx-3, Vascular Oxidant Stress, and Thrombosis
    Joseph Loscalzo; Fiscal Year: 2006
    ..abstract_text> ..