x ray computed tomography

Summary

Summary: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

Top Publications

  1. ncbi Coronary calcium as a predictor of coronary events in four racial or ethnic groups
    Robert Detrano
    Department of Radiological Sciences, University of California at Irvine, Irvine, CA 92697, USA
    N Engl J Med 358:1336-45. 2008
  2. ncbi Fleischner Society: glossary of terms for thoracic imaging
    David M Hansell
    Department of Radiology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, United Kingdom
    Radiology 246:697-722. 2008
  3. ncbi Computed tomography--an increasing source of radiation exposure
    David J Brenner
    Center for Radiological Research, Columbia University Medical Center, New York, NY 10032, USA
    N Engl J Med 357:2277-84. 2007
  4. ncbi Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society
    Heber Macmahon
    Radiology 237:395-400. 2005
  5. ncbi Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism
    A Furlan
    Cerebrovascular Center, Department of Neurology, Cleveland Clinic Foundation, Ohio 44195, USA
    JAMA 282:2003-11. 1999
  6. ncbi Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome
    Sadako Motoyama
    Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Japan
    J Am Coll Cardiol 54:49-57. 2009
  7. ncbi Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coro
    Matthew J Budoff
    Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, California, USA
    J Am Coll Cardiol 52:1724-32. 2008
  8. ncbi Attenuation of skeletal muscle and strength in the elderly: The Health ABC Study
    B H Goodpaster
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Appl Physiol (1985) 90:2157-65. 2001
  9. ncbi Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system
    Jerry L Barker
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:960-70. 2004
  10. ncbi Early Lung Cancer Action Project: overall design and findings from baseline screening
    C I Henschke
    Weill Medical College of Cornell University and New York Presbyterian Hospital, NY 10021, USA
    Lancet 354:99-105. 1999

Detail Information

Publications303 found, 100 shown here

  1. ncbi Coronary calcium as a predictor of coronary events in four racial or ethnic groups
    Robert Detrano
    Department of Radiological Sciences, University of California at Irvine, Irvine, CA 92697, USA
    N Engl J Med 358:1336-45. 2008
    ..However, it is not known whether coronary-artery calcium predicts coronary heart disease in other racial or ethnic groups...
  2. ncbi Fleischner Society: glossary of terms for thoracic imaging
    David M Hansell
    Department of Radiology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, United Kingdom
    Radiology 246:697-722. 2008
    ..Brief descriptions of some diseases are included, and pictorial examples (chest radiographs and CT scans) are provided for the majority of terms...
  3. ncbi Computed tomography--an increasing source of radiation exposure
    David J Brenner
    Center for Radiological Research, Columbia University Medical Center, New York, NY 10032, USA
    N Engl J Med 357:2277-84. 2007
  4. ncbi Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society
    Heber Macmahon
    Radiology 237:395-400. 2005
    ....
  5. ncbi Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism
    A Furlan
    Cerebrovascular Center, Department of Neurology, Cleveland Clinic Foundation, Ohio 44195, USA
    JAMA 282:2003-11. 1999
    ..Intravenous tissue-type plasminogen activator can be beneficial to some patients when given within 3 hours of stroke onset, but many patients present later after stroke onset and alternative treatments are needed...
  6. ncbi Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome
    Sadako Motoyama
    Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Japan
    J Am Coll Cardiol 54:49-57. 2009
    ..In a computed tomographic (CT) angiography study, we identified the characteristics of atherosclerotic lesions that were associated with subsequent development of acute coronary syndrome (ACS)...
  7. ncbi Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coro
    Matthew J Budoff
    Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, California, USA
    J Am Coll Cardiol 52:1724-32. 2008
    ..The purpose of this study was to evaluate the diagnostic accuracy of electrocardiographically gated 64-multidetector row coronary computed tomographic angiography (CCTA) in individuals without known coronary artery disease (CAD)...
  8. ncbi Attenuation of skeletal muscle and strength in the elderly: The Health ABC Study
    B H Goodpaster
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Appl Physiol (1985) 90:2157-65. 2001
    ..These results demonstrate that the attenuation values of muscle on computed tomography in older persons can account for differences in muscle strength not attributed to muscle quantity...
  9. ncbi Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system
    Jerry L Barker
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:960-70. 2004
    ..We conducted a pilot study to quantify the magnitude of these anatomic changes with systematic CT imaging...
  10. ncbi Early Lung Cancer Action Project: overall design and findings from baseline screening
    C I Henschke
    Weill Medical College of Cornell University and New York Presbyterian Hospital, NY 10021, USA
    Lancet 354:99-105. 1999
    ..The Early Lung Cancer Action Project (ELCAP) is designed to evaluate baseline and annual repeat screening by low-radiation-dose computed tomography (low-dose CT) in people at high risk of lung cancer. We report the baseline experience...
  11. ncbi Indications for computed tomography in patients with minor head injury
    M J Haydel
    Section of Emergency Medicine, Louisiana State University Health Science Center at New Orleans, USA
    N Engl J Med 343:100-5. 2000
    ..We performed a study to develop and validate a set of clinical criteria that could be used to identify patients with minor head injury who do not need to undergo CT...
  12. ncbi Subarachnoid haemorrhage: diagnosis, causes and management
    J van Gijn
    Department of Neurology, University Medical Centre, Utrecht, The Netherlands
    Brain 124:249-78. 2001
    ..Once ischaemia has occurred, treatment regimens such as a combination of induced hypertension and hypervolaemia, or transluminal angioplasty, are plausible, but of unproven benefit...
  13. ncbi Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study
    W Bob Meijboom
    Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands
    J Am Coll Cardiol 52:2135-44. 2008
    ..This study sought to determine the diagnostic accuracy of 64-slice computed tomographic coronary angiography (CTCA) to detect or rule out significant coronary artery disease (CAD)...
  14. ncbi Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content
    B H Goodpaster
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Appl Physiol (1985) 89:104-10. 2000
    ....
  15. ncbi MicroCT for developmental biology: a versatile tool for high-contrast 3D imaging at histological resolutions
    Brian D Metscher
    Department of Theoretical Biology, University of Vienna, Vienna, Austria
    Dev Dyn 238:632-40. 2009
    ..These methods establish microCT imaging as a useful tool for comparative developmental studies, embryo phenotyping, and quantitative modeling of development...
  16. ncbi Aorto-iliac multidetector-row CT angiography with low kV settings: improved vessel enhancement and simultaneous reduction of radiation dose
    B Wintersperger
    Department of Clinical Radiology, University of Munich, Marchioninistrasse 15, 81377, Munich, Germany
    Eur Radiol 15:334-41. 2005
    ..7+/-0.4 vs 10.1+/-1.2 mSv; P<0.0001). Tube kVp reduction from 120 to 100 kVp allows for significant reduction of patient dose in abdominal CT angiography, without significant change in SNR,CNR and image quality...
  17. pmc Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD
    R A O'Donnell
    Respiratory Cell and Molecular Biology, Division of Infection, Inflammation and Repair, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK
    Thorax 59:837-42. 2004
    ..A number of research tools have been combined to study smokers with a range of COPD severities classified according to the GOLD criteria...
  18. ncbi Perfusion-CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke
    Max Wintermark
    Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    Stroke 37:979-85. 2006
    ....
  19. ncbi Staging of non-small-cell lung cancer with integrated positron-emission tomography and computed tomography
    Didier Lardinois
    Divisions of Thoracic Surgery, University Hospital of Zurich, Zurich, Switzerland
    N Engl J Med 348:2500-7. 2003
    ....
  20. ncbi Combined pulmonary fibrosis and emphysema: a distinct underrecognised entity
    V Cottin
    Groupe d Etudes et de Recherche sur les Maladies Orphelines Pulmonaires, Hopital Cardiovasculaire et Pneumologique Louis Pradel, Universite Claude Bernard, Lyon Bron, France
    Eur Respir J 26:586-93. 2005
    ....
  21. ncbi Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis
    W G Goodman
    Department of Medicine, UCLA School of Medicine, Los Angeles, CA, USA
    N Engl J Med 342:1478-83. 2000
    ....
  22. ncbi Prognostic value of coronary artery calcium screening in subjects with and without diabetes
    Paolo Raggi
    Section of Cardiology, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA
    J Am Coll Cardiol 43:1663-9. 2004
    ..The study was done to determine the interaction of coronary artery calcium and diabetes mellitus for prediction of all-cause death...
  23. ncbi Four-dimensional (4D) PET/CT imaging of the thorax
    S A Nehmeh
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Med Phys 31:3179-86. 2004
    ..4D PET/CT acquisition can reduce smearing, improve the accuracy in PET-CT co-registration, and increase the measured SUV. This should result in an improved tumor assessment for patients with lung malignancies...
  24. ncbi Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR imaging, and FDG PET and validation with surgical specimen
    Jean François Daisne
    Head and Neck Oncology Program, St Luc University Hospital, Universite Catholique de Louvain, 10 Ave Hippocrate, 1200 Brussels, Belgium
    Radiology 233:93-100. 2004
    ....
  25. ncbi Airflow limitation and airway dimensions in chronic obstructive pulmonary disease
    Masaru Hasegawa
    First Department of Medicine, Hokkaido University School of Medicine, N 15 W 7 Kita ku, Sapporo 060 8638, Japan
    Am J Respir Crit Care Med 173:1309-15. 2006
    ..Computed tomography has been widely used to assess emphysema severity, but less attention has been paid to the assessment of airway disease using computed tomography...
  26. ncbi Risk-based selection from the general population in a screening trial: selection criteria, recruitment and power for the Dutch-Belgian randomised lung cancer multi-slice CT screening trial (NELSON)
    Carola A Van Iersel
    Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
    Int J Cancer 120:868-74. 2007
    ..When pooling with Danish trial data (n = +/-4,000) NELSON is the only trial without screening in controls that is expected to have 80% power to show a lung cancer mortality reduction of at least 25% 10 years after randomisation...
  27. ncbi Perfusion CT: a worthwhile enhancement?
    K A Miles
    Southernex Imaging Group, Wesley Hospital, Chasely Street, Auchenflower, Queensland 4066, Australia
    Br J Radiol 76:220-31. 2003
  28. ncbi The Canadian CT Head Rule for patients with minor head injury
    I G Stiell
    Divisions of Emergency Medicine, University of British Columbia, Vancouver, Canada
    Lancet 357:1391-6. 2001
    ..There is much controversy about the use of computed tomography (CT) for patients with minor head injury. We aimed to develop a highly sensitive clinical decision rule for use of CT in patients with minor head injuries...
  29. ncbi Perfusion CT for the assessment of tumour vascularity: which protocol?
    K A Miles
    Division of Clinical and Laboratory Investigation, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton BN1 9PX, UK
    Br J Radiol 76:S36-42. 2003
    ..This article discusses the advantages and disadvantages of the more common CT perfusion protocols and offers proposals that could allow for easier comparison between studies employing different techniques...
  30. ncbi Four-dimensional computed tomography: image formation and clinical protocol
    Eike Rietzel
    Massachusetts General Hospital, Department of Radiation Oncology, Boston, Massachusetts 02114, USA
    Med Phys 32:874-89. 2005
    ..A protocol for 4DCT scanning was evaluated and clinically implemented at the MGH. Patient data are presented to elucidate how additional patient specific parameters can impact 4DCT imaging...
  31. ncbi Extraadrenal paragangliomas of the body: imaging features
    Ki Yeol Lee
    Department of Radiology, Korea University Anam Hospital, College of Medicine Korea University 126 1, 5 Ka, Anam Dong, Sungbuk Ku, Seoul 136 705, Korea
    AJR Am J Roentgenol 187:492-504. 2006
    ..This article illustrates the anatomic distribution of the healthy paraganglion system and the imaging and pathologic features of various extraadrenal paragangliomas occurring in the head and neck, chest, and abdomen...
  32. ncbi The prediction of small airway dimensions using computed tomography
    Yasutaka Nakano
    Department of Respiratory Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan
    Am J Respir Crit Care Med 171:142-6. 2005
    ..01). We conclude that CT measurements of airways with a Pi of 0.75 cm or more could be used to estimate the dimensions of the small conducting airways, which are the site of airway obstruction in chronic obstructive pulmonary disease...
  33. ncbi Drug-induced lung disease: high-resolution CT and histological findings
    Joanne R Cleverley
    Department of Radiology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    Clin Radiol 57:292-9. 2002
    ..To compare the parenchymal high-resolution computed tomography (HRCT) appearances with histological findings in patients with drug-induced lung disease and to determine the prognostic value of HRCT...
  34. ncbi Feasibility of low-dose coronary CT angiography: first experience with prospective ECG-gating
    Lars Husmann
    Department of Medical Radiology and Cardiovascular Center, University Hospital Zurich, Raemistr 100, CH 8091 Zurich, Switzerland
    Eur Heart J 29:191-7. 2008
    ..To determine the feasibility of prospective electrocardiogram (ECG)-gating to achieve low-dose computed tomography coronary angiography (CTCA)...
  35. ncbi Improvements in cancer staging with PET/CT: literature-based evidence as of September 2006
    Johannes Czernin
    Department of Molecular and Medical Pharmacology, Ahmanson Biological Imaging Clinic Nuclear Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California 90095 6948, USA
    J Nucl Med 48:78S-88S. 2007
    ..From these data, we believe, has emerged reliable evidence in support of the notion that PET/CT offers diagnostic advantages over its individual components for the major cancers...
  36. ncbi Automated detection of pulmonary nodules in helical CT images based on an improved template-matching technique
    Y Lee
    Department of Radiological Technology, School of Health Sciences, Faculty of Medicine, Niigata University, Japan
    IEEE Trans Med Imaging 20:595-604. 2001
    ..1/sectional image. Our present results show that our scheme can be regarded as a technique for CAD systems to detect nodules in helical CT pulmonary images...
  37. ncbi Relationship between noninvasive coronary angiography with multi-slice computed tomography and myocardial perfusion imaging
    Joanne D Schuijf
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 48:2508-14. 2006
    ....
  38. ncbi Gastrointestinal stromal tumors: radiologic features with pathologic correlation
    Angela D Levy
    Department of Radiologic Pathology, Armed Forces Institute of Pathology, 6825 16th St NW, Washington, DC 20306 6000, USA
    Radiographics 23:283-304, 456; quiz 532. 2003
    ..Although the radiologic features of GISTs are often distinct from those of epithelial tumors, criteria to separate GISTs radiologically from other nonepithelial tumors have not yet been fully developed...
  39. ncbi Enhancement of focal liver lesions at gadoxetic acid-enhanced MR imaging: correlation with histopathologic findings and spiral CT--initial observations
    Alexander Huppertz
    Department of Clinical Radiology and Institute of Pathology, Ludwig Maximilians University, Munich, Germany
    Radiology 234:468-78. 2005
    ....
  40. ncbi Prognostic value of multislice computed tomography and gated single-photon emission computed tomography in patients with suspected coronary artery disease
    Jacob M van Werkhoven
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 53:623-32. 2009
    ....
  41. ncbi Chronic obstructive pulmonary disease: thin-section CT measurement of airway wall thickness and lung attenuation
    Ilaria Orlandi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, Florence 50134, Italy
    Radiology 234:604-10. 2005
    ....
  42. pmc Image-guided tumor ablation: standardization of terminology and reporting criteria
    S Nahum Goldberg
    Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    Radiology 235:728-39. 2005
    ....
  43. ncbi CT dose reduction and dose management tools: overview of available options
    Cynthia H McCollough
    Department of Radiology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    Radiographics 26:503-12. 2006
    ..Modulation both angularly around the patient and along the z-axis is optimal, but the tube current must be appropriately adapted to patient size for diagnostic image quality to be achieved...
  44. ncbi National survey of doses from CT in the UK: 2003
    P C Shrimpton
    Radiation Protection Division, Health Protection Agency, Chilton, Didcot, Oxon OX11 0RQ, UK
    Br J Radiol 79:968-80. 2006
    ..The survey has established the PREDICT (Patient Radiation Exposure and Dose in CT) database as a sustainable national resource for monitoring dose trends in CT through the ongoing collation of further survey data...
  45. ncbi Small pulmonary nodules: volumetrically determined growth rates based on CT evaluation
    D F Yankelevitz
    Department of Radiology, New York Presbyterian Hospital Weill Cornell Medical Center, Building Starr 8A23, 525 E 68th St, New York, NY 10021, USA
    Radiology 217:251-6. 2000
    ..To determine the accuracy of high-resolution computed tomographic (CT) volumetric measurements of small pulmonary nodules to assess growth and malignancy status...
  46. ncbi Comparison of CT- and FDG-PET-defined gross tumor volume in intensity-modulated radiotherapy for head-and-neck cancer
    Arnold C Paulino
    Department of Radiation Oncology, Division of Nuclear Medicine and Molecular Imaging, Emory Clinic and Emory University, Atlanta, GA, USA
    Int J Radiat Oncol Biol Phys 61:1385-92. 2005
    ....
  47. pmc Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison
    Julio A Chalela
    Medical University of South Carolina, Charleston, SC, USA
    Lancet 369:293-8. 2007
    ..We aimed to prospectively compare CT and MRI for emergency diagnosis of acute stroke...
  48. ncbi An improved segmentation method for in vivo microCT imaging
    Jan H Waarsing
    Department of Orthopaedics, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Bone Miner Res 19:1640-50. 2004
    ..The new method can improve the results of in vivo microCT, where the need to keep radiation dose low limits scan quality...
  49. ncbi Solitary fibrous tumors of the pleura: surgical outcome and clinical course
    Sook Hwan Sung
    Department of Thoracic Surgery, Seoul National University, Seoul, South Korea
    Ann Thorac Surg 79:303-7. 2005
    ..The aim of this study was to define more precisely the surgical outcome and clinical course of solitary fibrous tumors of the pleura...
  50. ncbi Blood flow-metabolic relationships are dependent on tumour size in non-small cell lung cancer: a study using quantitative contrast-enhanced computer tomography and positron emission tomography
    K A Miles
    Division of Clinical and Laboratory Sciences, Brighton and Sussex Medical School, University of Sussex, Brighton, BN7 3PB, UK
    Eur J Nucl Med Mol Imaging 33:22-8. 2006
    ....
  51. ncbi Treatment of hepatocellular carcinoma with radiofrequency ablation: radiologic-histologic correlation during follow-up periods
    Manabu Morimoto
    Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan
    Hepatology 35:1467-75. 2002
    ..These pathologic findings can be correlated with those of contrast-enhanced CT...
  52. ncbi Acute appendicitis: meta-analysis of diagnostic performance of CT and graded compression US related to prevalence of disease
    Adrienne van Randen
    Department of Radiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Suite G1 227, 1105 AZ Amsterdam, The Netherlands
    Radiology 249:97-106. 2008
    ....
  53. ncbi Measures of response: RECIST, WHO, and new alternatives
    C Carl Jaffe
    Diagnostic Imaging Branch, Cancer Imaging Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    J Clin Oncol 24:3245-51. 2006
    ....
  54. ncbi Risk factors for occult mediastinal metastases in clinical stage I non-small cell lung cancer
    Paul C Lee
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, New York 10021, USA
    Ann Thorac Surg 84:177-81. 2007
    ..The goal of this study was to analyze the risk factors for occult mediastinal metastases in this subset of patients...
  55. ncbi Lung cancer: performance of automated lung nodule detection applied to cancers missed in a CT screening program
    Samuel G Armato
    Kurt Rossmann Laboratories for Radiologic Image Research, Department of Radiology, University of Chicago, 5841 S Maryland Ave, MC 2026, Chicago, IL 60637, USA
    Radiology 225:685-92. 2002
    ..To evaluate the performance of a fully automated computerized method for the detection of lung nodules in computed tomographic (CT) scans in the identification of lung cancers that may be missed during visual interpretation...
  56. ncbi Low-dose CT of the abdomen: evaluation of image improvement with use of noise reduction filters pilot study
    Mannudeep K Kalra
    Department of Radiology, Massachusetts General Hospital, Harvard Medical School, White 270 E, 55 Fruit St, Boston, MA 02114, USA
    Radiology 228:251-6. 2003
    ..05). A statistically significant reduction of noise in low-dose images processed with three filters was noted. In conclusion, use of noise reduction filters decreased image noise at low-dose CT...
  57. ncbi CT perfusion scanning with deconvolution analysis: pilot study in patients with acute middle cerebral artery stroke
    James D Eastwood
    Depts of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710 3808, USA
    Radiology 222:227-36. 2002
    ..To measure mean cerebral blood flow (CBF) in ischemic and nonischemic territories and in low-attenuation regions in patients with acute stroke by using deconvolution-derived hemodynamic imaging...
  58. ncbi Definition of postlumpectomy tumor bed for radiotherapy boost field planning: CT versus surgical clips
    Hadassah Goldberg
    Department of Oncology, Rambam Medical Center, Haifa, Israel
    Int J Radiat Oncol Biol Phys 63:209-13. 2005
    ..To compare the location and extent of the tumor bed as defined by surgical clips and computed tomography (CT) scans, after lumpectomy, for electron boost planning as part of breast radiotherapy...
  59. ncbi Differences of three-dimensional trabecular microstructure in osteopenic rat models caused by ovariectomy and neurectomy
    M Ito
    Department of Radiology, Nagasaki University School of Medicine, Nagasaki, Japan
    Bone 30:594-8. 2002
    ..Loading during bone resorption increased the anisotropy, whereas immobilization increased the isotropy. In addition, immobilization had a more significant effect on the cortical area...
  60. pmc Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption
    H Yoshitake
    Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3 10 Kanda Surugadai 2 Chome, Chiyoda ku, Tokyo, Japan
    Proc Natl Acad Sci U S A 96:8156-60. 1999
    ..We propose that osteopontin is essential for postmenopausal osteoporosis in women. Strategies to counteract osteopontin's action may prove effective in suppressing osteoporosis...
  61. ncbi Radioimmunoguided surgery (RIGS), PET/CT image-guided surgery, and fluorescence image-guided surgery: past, present, and future
    Duxin Sun
    Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA
    J Surg Oncol 96:297-308. 2007
    ..PET/CT image-guided surgery only detects later stage disease. Fluorescence image-guided surgery using anti-TAG-72 antibodies may provide opportunities for intraoperative cancer detection of both gross and occult tumors...
  62. ncbi Bladder tumor detection at virtual cystoscopy
    J H Song
    Dept of Radiology, University of Michigan Hospital, UH B2B311D 0030, 1500 E Medical Center Dr, Ann Arbor, MI 48109 0030, USA
    Radiology 218:95-100. 2001
    ..To investigate the utility of computed tomographic (CT) virtual cystoscopy in the detection of bladder tumors...
  63. ncbi Evaluation of cystic renal masses: comparison of CT and MR imaging by using the Bosniak classification system
    Gary M Israel
    Department of Radiology, NYU Medical Center, 560 First Ave, Suite HW 202, New York, NY 10016, USA
    Radiology 231:365-71. 2004
    ..To compare computed tomography (CT) and magnetic resonance (MR) imaging in the evaluation of cystic renal masses by using the Bosniak classification system...
  64. ncbi Lung cancer: interobserver agreement on interpretation of pulmonary findings at low-dose CT screening
    David S Gierada
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, St Louis, MO 63105, USA
    Radiology 246:265-72. 2008
    ..To evaluate agreement among radiologists on the interpretation of pulmonary findings at low-dose computed tomographic (CT) screening examinations for lung cancer...
  65. ncbi Image quality and radiation exposure at pulmonary CT angiography with 100- or 120-kVp protocol: prospective randomized study
    Christoph M Heyer
    Institute of Diagnostic Radiology, Interventional Radiology and Nuclear Medicine, BG Clinics Bergmannsheil, Ruhr University of Bochum, Buerkle de la Camp Platz 1, D 44789, Bochum, Germany
    Radiology 245:577-83. 2007
    ..To prospectively compare 16-section multidetector computed tomography (CT) at 100 and 120 kVp for image quality and radiation dose...
  66. ncbi T staging of gastric cancer: role of multi-detector row CT
    Seishi Kumano
    Department of Radiology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 5650871, Japan
    Radiology 237:961-6. 2005
    ..To evaluate retrospectively the accuracy of multi-detector row computed tomography (CT) in the assessment of serosal invasion in patients with gastric cancer...
  67. ncbi Diagnostic patterns and temporal trends in the evaluation of adult patients hospitalized with syncope
    L A Pires
    Department of Medicine, St John Hospital and Medical Center, 22101 Moross, Detroit, MI 48236, USA
    Arch Intern Med 161:1889-95. 2001
    ..Syncope is a common clinical problem that is often difficult and expensive to diagnose. We examined diagnostic patterns and trends and use of specialty consultations in the evaluation of syncope...
  68. ncbi Diagnostic performance of multidetector CT angiography for assessment of coronary artery disease: meta-analysis
    Piet K Vanhoenacker
    Department of Radiology and Medical Imaging, OLV Ziekenhuis Aalst, Moorselbaan 164, 9300 Aalst, Belgium
    Radiology 244:419-28. 2007
    ..To review the literature on the diagnostic performance of multidetector computed tomographic (CT) angiography for assessment of symptomatic coronary artery disease, with conventional coronary angiography as the reference standard...
  69. ncbi Computed tomographic imaging of the airways: relationship to structure and function
    P A de Jong
    Dept of Paediatric Pulmonology, Erasmus MC Sophia, Rotterdam, The Netherlands
    Eur Respir J 26:140-52. 2005
    ..The aim of this article is to review the use of computed tomography in the investigation of airway structure and function in health and disease...
  70. ncbi Clinical impact of integrated PET/CT on the management of suspected cervical cancer recurrence
    Hyun Hoon Chung
    Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul 110 744, South Korea
    Gynecol Oncol 104:529-34. 2007
    ..To assess the value and clinical impact of integrated PET/CT using (18)F-FDG in the diagnosis and management of women with suspected cervical cancer recurrence...
  71. ncbi Hemorrhagic transformation of ischemic brain tissue: asymptomatic or symptomatic?
    C Berger
    Department of Neurology, University of Heidelberg, Germany
    Stroke 32:1330-5. 2001
    ..The aim of this study was to assess which type of HT independently affects clinical outcome...
  72. ncbi Measurement of tumor volume by PET to evaluate prognosis in patients with advanced cervical cancer treated by radiation therapy
    Tom R Miller
    Mallinckrodt Institute of Radiology, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 53:353-9. 2002
    ..This study evaluated the usefulness of tumor volume measurement with positron emission tomography (PET) in patients with advanced cervical cancer treated by radiation therapy...
  73. ncbi 4-dimensional computed tomography imaging and treatment planning
    Paul Keall
    Department of Radiation Oncology, Virginia Commonwealth University, Richmond 23298 0058, USA
    Semin Radiat Oncol 14:81-90. 2004
    ..This article discusses methodology for 4D CT imaging and 4D treatment planning, with some comments on 4D radiation delivery...
  74. ncbi CT-guided needle biopsy of lung lesions: a survey of severe complication based on 9783 biopsies in Japan
    Noriyuki Tomiyama
    Department of Radiology, Osaka University Graduated School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Eur J Radiol 59:60-4. 2006
    ..The aim of our study was to update the rate of severe complications following CT-guided needle biopsy in Japan via a mailed survey...
  75. ncbi Interstitial CT lymphography-guided localization of breast sentinel lymph node: preliminary results
    Kazuyoshi Suga
    Department of Radiology, Yamaguchi University School of Medicine, 1 1 1 Minamikogushi, Ube, Yamaguchi 755 8505, Japan
    Surgery 133:170-9. 2003
    ..We tested the potential capability of interstitial computed tomographic lymphography (CT-LG) using a conventional contrast agent (iopamidol) for SLN mapping...
  76. ncbi Evaluation of deformable registration of patient lung 4DCT with subanatomical region segmentations
    Ziji Wu
    Department of Radiation Oncology, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts 02114, USA
    Med Phys 35:775-81. 2008
    ..Statistical analyses of the mismatch of the homologous points before and after registration demonstrated improved overall accuracy for both algorithms...
  77. ncbi Predisposing factors of bile duct injury after transcatheter arterial chemoembolization (TACE) for hepatic malignancy
    Jeong Sik Yu
    Department of Diagnostic Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Yongdong Severance Hospital, 146 92 Dogok dong, Gangnam Gu, Seoul 135 270, South Korea
    Cardiovasc Intervent Radiol 25:270-4. 2002
    ..05). It was concluded that the chance of bile duct injury after TACE is increased in non-cirrhotic livers with good liver profile and to the more selective embolization of distal arterial branches...
  78. ncbi Patterns of failure in patients receiving definitive and postoperative IMRT for head-and-neck cancer
    K S Clifford Chao
    Department of Radiation Oncology, Washington University Medical School, St Louis, MO, USA
    Int J Radiat Oncol Biol Phys 55:312-21. 2003
    ..To analyze the patterns of locoregional failure in patients with head-and-neck cancer treated with inverse planning intensity-modulated radiotherapy (IMRT)...
  79. ncbi Steroid therapy for idiopathic retroperitoneal fibrosis: dose and duration
    A H Kardar
    Department of Urology, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia
    J Urol 168:550-5. 2002
    ..However, there is no agreement as to the dose and duration of steroid. We adopted a regimen of long-term steroid use in this prospective study...
  80. ncbi Adrenal masses: characterization with combined unenhanced and delayed enhanced CT
    Elaine M Caoili
    Department of Radiology, University of Michigan Medical Center, 1500 E Medical Center Dr, Ann Arbor, MI 48109 9723, USA
    Radiology 222:629-33. 2002
    ..To assess the accuracy of a dedicated adrenal computed tomographic (CT) protocol...
  81. ncbi Malignant tumor, of the gastrointestinal stromal tumor type, in the greater omentum
    Kazufumi Suzuki
    Department of Surgery, Tatsuno General Hospital, 3351 Ooaza Inatomi, Tatsunocho, Kamiina gun, 399 0426, Nagano, Japan
    J Gastroenterol 38:985-8. 2003
    ..The patient died of hypovolemic shock. Necropsy revealed that rupture of one of the metastatic liver tumors had resulted in a massive intraperitoneal hemorrhage...
  82. pmc Strategies for reducing radiation dose in CT
    Cynthia H McCollough
    Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Radiol Clin North Am 47:27-40. 2009
    ..To satisfy the ALARA principle, the dose reduction strategies described in this article must be well understood and properly used. The use of CT must also be justified for the specific diagnostic task...
  83. ncbi Multidetector-row computed tomography in suspected pulmonary embolism
    Arnaud Perrier
    Service of General Internal Medicine, Geneva Faculty of Medicine and Geneva University Hospital, Geneva, Switzerland
    N Engl J Med 352:1760-8. 2005
    ..We evaluated whether the use of D-dimer measurement and multidetector-row CT, without lower-limb ultrasonography, might safely rule out pulmonary embolism...
  84. ncbi Comparison of three different mediastinal radiotherapy techniques in female patients: Impact on heart sparing and dose to the breasts
    Carsten Nieder
    Department of Radiation Oncology, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Germany
    Radiother Oncol 82:301-7. 2007
    ..Especially in highly curable diseases such as lymphoma, long-term survivors might develop late cardiac damage and radiation-induced second cancer...
  85. ncbi Accuracy of dynamic perfusion CT with deconvolution in detecting acute hemispheric stroke
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, USA
    AJNR Am J Neuroradiol 26:104-12. 2005
    ..We determined the accuracy of these maps in patients with suspected acute hemispheric stroke...
  86. ncbi 18F-FDG PET definition of gross tumor volume for radiotherapy of non-small cell lung cancer: is a single standardized uptake value threshold approach appropriate?
    Kenneth J Biehl
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri, USA
    J Nucl Med 47:1808-12. 2006
    ....
  87. ncbi Vascular calcification and cardiovascular function in chronic kidney disease
    Mhairi Sigrist
    Department of Renal Medicine, Derby City General Hospital, Derby, DE22 3NE, UK
    Nephrol Dial Transplant 21:707-14. 2006
    ..Few data are currently available comparing vascular calcification and its attendant functional cardiovascular consequences between CKD stage 4 patients and both peritoneal dialysis (PD) and haemodialysis (HD) (CKD stage 5) patients...
  88. ncbi Comparison of CT and sonography in the diagnosis of acute appendicitis: a blinded prospective study
    Pieter Poortman
    Department of Surgery, St Elisabeth Hospital Tilburg, Hilvarenbeekseweg 60, 5000 LC Tilburg, The Netherlands
    AJR Am J Roentgenol 181:1355-9. 2003
    ..The results, independently reported, were correlated with surgical and histopathologic findings...
  89. doi Noninvasive coronary artery imaging: magnetic resonance angiography and multidetector computed tomography angiography: a scientific statement from the american heart association committee on cardiovascular imaging and intervention of the council on cardio
    David A Bluemke
    Circulation 118:586-606. 2008
  90. ncbi Medical radiation exposure in the U.S. in 2006: preliminary results
    Fred A Mettler
    Radiology and Nuclear Medicine Service, New Mexico VA Health Care System, Albuquerque, NM 87108, USA
    Health Phys 95:502-7. 2008
    ..Nuclear medicine accounted for about 4% of all procedures but 26% of the total collective dose. Medical radiation exposure is now approximately equal to natural background radiation...
  91. ncbi Recurrences of hepatocellular carcinoma following initial remission by transcatheter arterial chemoembolization
    Jae Kyun Lee
    Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    J Gastroenterol Hepatol 17:52-8. 2002
    ....
  92. ncbi Thin-section CT in obstructive pulmonary disease: discriminatory value
    Susan J Copley
    Department of Radiology, Hammersmith Hospital, London, England
    Radiology 223:812-9. 2002
    ..To use thin-section computed tomography (CT) to distinguish between causes of obstructive pulmonary disease, to determine which distinctions give rise to diagnostic imprecision, and to identify the most useful CT features...
  93. ncbi Local denervation atrophy of paraspinal muscles in postoperative failed back syndrome
    T Sihvonen
    Department of Clinical Neurophysiology, University Hospital, Kuopio, Finland
    Spine (Phila Pa 1976) 18:575-81. 1993
    ..It may be possible to develop operating techniques that save back muscle innervation better than the usual ones...
  94. ncbi Comparative overview of brain perfusion imaging techniques
    Max Wintermark
    Department of Radiology, University of California, 505 Parnassus Ave, San Francisco, CA 94143 0628, USA
    Stroke 36:e83-99. 2005
    ..All of them are used to characterize the same types of pathological conditions. However, each technique has its own advantages and drawbacks...
  95. ncbi Diagnostic CT scans: assessment of patient, physician, and radiologist awareness of radiation dose and possible risks
    Christoph I Lee
    Department of Diagnostic Radiology, Yale University, 333 Cedar St, TE 2, New Haven, CT 06520, USA
    Radiology 231:393-8. 2004
    ..To determine the awareness level concerning radiation dose and possible risks associated with computed tomographic (CT) scans among patients, emergency department (ED) physicians, and radiologists...
  96. pmc Noncalcified lung nodules: volumetric assessment with thoracic CT
    Marios A Gavrielides
    National Institute of Biomedical Imaging and Bioengineering Center for Devices and Radiological Health, U S Food and Drug Administration, Silver Spring, MD 20993 0002, USA
    Radiology 251:26-37. 2009
    ....
  97. ncbi Immediate repair compared with surveillance of small abdominal aortic aneurysms
    Frank A Lederle
    Veterans Affairs Medical Centers in Minneapolis, MN 55417, USA
    N Engl J Med 346:1437-44. 2002
    ..Whether elective surgical repair of small abdominal aortic aneurysms improves survival remains controversial...
  98. ncbi Small hepatocellular carcinoma: comparison of radio-frequency ablation and percutaneous microwave coagulation therapy
    Toshiya Shibata
    Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Kawaharacho, Shogoin, Sakyoku, Kyoto 606 8507, Japan
    Radiology 223:331-7. 2002
    ..To evaluate the effectiveness of radio-frequency (RF) ablation and percutaneous microwave coagulation (PMC) for treatment of hepatocellular carcinoma (HCC)...
  99. ncbi Bone imaging in metastatic breast cancer
    Tsuyoshi Hamaoka
    Breast Cancer Research Program, Department of Blood and Marrow Transplantation, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 448, Houston, TX 77030, USA
    J Clin Oncol 22:2942-53. 2004
    ....
  100. ncbi PET imaging of somatostatin receptors using [68GA]DOTA-D-Phe1-Tyr3-octreotide: first results in patients with meningiomas
    M Henze
    Department of Nuclear Medicine, University of Heidelberg, Heidelberg, Germany
    J Nucl Med 42:1053-6. 2001
    ..CONCLUSION: According to our initial experiences, [68Ga]DOTATOC seems to be a very promising new PET tracer for imaging SSTRs even in small meningiomas, offering excellent imaging properties and a very high tumor-to-background ratio...
  101. ncbi Quantitative computed tomography of chronic obstructive pulmonary disease
    Harvey O Coxson
    Department of Radiology and James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada V5Z 1M9
    Acad Radiol 12:1457-63. 2005
    ..This review describes some of these CT techniques for quantitative assessment of lung structure...

Research Grants64

  1. PET/SPECT/CT Camera for Small Animal Imaging at UMMS
    Donald Hnatowich; Fiscal Year: 2007
    ..We believe that this application addresses the goals of the NIH in offering the RFA and the goals of UMMS to expand use on our campus of small animal imaging. [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  2. Role of Oxidative Stress and Inflammation in HIV Cardiovascular Risk
    Cecilia M Shikuma; Fiscal Year: 2012
    ..End of Abstract) ..
  3. Epidemiology of CHD of Men Aged 40+ in US, Hawaii, Japan
    Akira Sekikawa; Fiscal Year: 2012
    ....
  4. Automatic Segmentation of Organs in Computed Tomography for Radiation Therapy Pla
    MARK MCKENZIE RODEN; Fiscal Year: 2011
    ....
  5. Preclinical Efficacy And Safety Evaluation Of Graphene Nanoparticle-based Magneti
    Balaji Sitharaman; Fiscal Year: 2013
    ..The GNP-Dex could also due to their high-efficacy be used in clinic for other applications as an alternative off-the-label MRI CA to currently existing gadolinium-basedT1 MRI CAs. ..
  6. Load-mediated Adaptation of the Bone-PDL-Tooth Complex in Vertebrates
    Sunita P Ho; Fiscal Year: 2013
    ..Such adapted sites could act as the local stress points inducing positive feedback when the complex is subjected to implants and/or periodontitis, normal or therapeutic loads (orthodontic braces) subsequently impairing function. ..
  7. Non-Invasive Localization of Vulnerable Plaques
    Cynthia McCollough; Fiscal Year: 2009
    ....
  8. High Resolution Multiplexed Fluorescence Tomography
    MARK JONATHAN NIEDRE; Fiscal Year: 2013
    ..We anticipate that the scanner will have many applications in biomedical research including studying disease development and response to novel therapeutics in vivo. ..
  9. MOLECULAR PROBES AND METHODS FOR FLUORESCENCE LIFETIME TOMOGRAPHY AND MICROSCOPY
    Samuel Achilefu; Fiscal Year: 2012
    ....
  10. Development of Thermoacoustic Tomography Brain Imaging
    Mark A Anastasio; Fiscal Year: 2013
    ....
  11. Cross-scale interactions between mineral and collagen for tendon-bone attachment
    Stavros Thomopoulos; Fiscal Year: 2013
    ..Together, these models and data form the foundation of future tissue engineering efforts and efforts to identify clinically useful metrics of tendon-to-bone tissue health. ..
  12. Development of a PEM-PET-CT Breast Imaging and Biopsy Device
    RAYMOND ROBERT RAYLMAN; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE This application proposes the continued development of a dedicated breast PET-CT system. This device could be instrumental in the detection, diagnosis and treatment assessment of breast cancer. ..
  13. CT-based Phenotype for Airway Remodeling in COPD based on Airway Wall Density
    Raul San Jose Estepar; Fiscal Year: 2013
    ..San Josi Estipar into an established independent quantitative research scientist with the expertise to develop image-based quantitative approaches to enable clinical and genetic studies in COPD and related lung diseases. ..
  14. Image-guided thermo-chemoembolization for treatment of liver cancer
    Eleni A Liapi; Fiscal Year: 2013
    ..The long- term objective of this effort is to provid a new image-guided strategy to counter primary liver cancer. ..
  15. Innovative Solid-State Photodetector for Applications in Medical Imaging
    Woon Seng Choong; Fiscal Year: 2011
    ....
  16. DENTIN STRUCTURE, DEMINERALIZATION AND REMINERALIZATION
    Grayson W Marshall; Fiscal Year: 2013
    ..Establishing methods to functionally remineralize dentin caries thereby restoring the mechanical properties of the hydrated tissue will minimize conventional restorative treatment and maximize conservation of tooth structure. ..
  17. Characterizing electrostatic interactions between glycosaminoglycans and cationic
    Brian D Snyder; Fiscal Year: 2013
    ....
  18. Simultaneous SPECT/CT with a single photon counting camera
    William C Barber; Fiscal Year: 2011
    ..Additionally, the detector can perform simultaneous SPECT and CT. The proposal submitted contains several innovative advancements to the current state of the art technologies employed in both CT and SPECT. ..
  19. Electro-optical Approach to Achieve Time-of-Flight PET/MRI for Cancer Imaging
    MATTHEW BIENIOSEK; Fiscal Year: 2012
    ....
  20. Gold-Loaded Polymeric Micelles
    Andrew Tsourkas; Fiscal Year: 2013
    ....
  21. Skyscan 1172 ex-vivo microComputed Tomography System
    Nicola C Partridge; Fiscal Year: 2013
    ..Acquisition of this equipment will enable our institutions to greatly improve the efficiency of biomedical research directly related to pathophysiological processes and animal models of human diseases. ..
  22. Photon Counting Detectors for Clinical k-edge CT
    William C Barber; Fiscal Year: 2012
    ..Photon counting detectors with energy binning can improve CT performance by counting and binning each x-ray detected. ..
  23. Optical Fluorescence and X-Ray Computed Tomography Scanner for Small Animal In-Vi
    SETH D SHULMAN; Fiscal Year: 2011
    ....
  24. Optical Fluorescence and X-Ray Computed Tomography Scanner for Small Animal In-Vi
    SETH D SHULMAN; Fiscal Year: 2012
    ....
  25. Tumor Detection and Quantitation with Emission Tomography
    Thomas K Lewellen; Fiscal Year: 2013
    ..Part of our effort will be to continue to improve SimSET with significance acceleration of SPECT collimator simulation tools. The SimSET software package is freely available via the Internet. ..
  26. In Vivo Optical Imaging Scanner for Small Animal Research
    STUART BERR; Fiscal Year: 2009
    ....
  27. Model-Based Image Reconstruction for X-ray CT in Lung Imaging
    Jeffrey A Fessler; Fiscal Year: 2012
    ....
  28. Efficient snap-shot CT imaging of the entire heart using staggered circular scans
    Frederic Noo; Fiscal Year: 2010
    ..The patients will therefore receive a lower radiation dose with an improved diagnostic, and the population of patients that can be imaged will be widened. ..
  29. FULLY THREE-DIMENSIONAL TOMOGRAPHY MEETING
    GRANT GULLBERG; Fiscal Year: 1993
    ....
  30. Northeastern Ohio Animal Imaging Resource Center- NOAIRC
    Jeffrey Duerk; Fiscal Year: 2006
    ..The result will be clinicians, scientists, and engineers trained for the next generation of conventional and molecular imaging techniques. ..
  31. VirtualDose Software for Diagnostic CT Doses to Adults and Children
    Xie George Xu; Fiscal Year: 2013
    ..3) To establish a comprehensive organ dose database by using the Monte Carlo CT scanner models and ICRP algorithms. (4) To develop and refine the software graphical user interfaces by using 3D object- oriented programming. ..
  32. A Needle Guidance System for Hepatic Tumor Ablation That Fuses Real-Time Ultrasou
    Sharif Razzaque; Fiscal Year: 2013
    ..Our proposed system has potential to dramatically improve the utility of CT in the operating room, increasing the likelihood of an effective, efficient and complete intervention and improved patient outcome. ..
  33. POLYMERIC MICELLAR CONTRAST AGENTS FOR CT ANGIOGRAPHY
    John Babich; Fiscal Year: 2000
    ..abstract_text> ..
  34. Rainbow CT: Cost-effective Spectral CT to increase image contrast and lower dose
    WILLIAM A WORSTELL; Fiscal Year: 2013
    ..In a later Phase II effort, we will develop and test an engineering prototype with which we will demonstrate the manufacturing feasibility and performance capability of a clinical CT system incorporating our new design. ..
  35. New Design of a Photon Counting Detector for Breast CT
    Vivek Nagarkar; Fiscal Year: 2009
    ..Outside medical use, this detector will be extremely important for such applications as X-ray inspections at airports and borders. ..
  36. VISUALIZING DIABETIC FEET TO OPTIMIZE ORTHOTIC FITTING
    Michael Mueller; Fiscal Year: 2006
    ..Experimental testing will help to keep computational models realistic and valid while three dimensional computational modeling will enhance the scientific basis of orthotic design and testing. ..
  37. Micro Computerized Tomography Imaging System
    PETER CONTI; Fiscal Year: 2004
    ....
  38. 122I GENERATOR AND RADIOTRACERS FOR PERFUSION STUDIES
    Thomas Budinger; Fiscal Year: 1999
    ..Comparisons of the selected compound will be made against 13NH and 62Cu-PTSM by dynamic PET in man. ..
  39. Quantitative periprosthetic PET/CT
    Thomas Lang; Fiscal Year: 2009
    ....
  40. Fast Photon-counting CZT Detector for CT Imaging
    NEAL HARTSOUGH; Fiscal Year: 2009
    ..These new features lead to potentially significantly reduced x-ray dose to the patient, compositional analysis of tissue through spectroscopic x-ray imaging, and potentially significant improvement in overall image quality. ..
  41. Skyscan 1172 ex-vivo microComputed Tomography System
    Francesco Ramirez; Fiscal Year: 2007
    ..Acquisition of this equipment will enable our institutions to engage in biomedical research highly relevant to pathophysiological processes and animal models of human diseases. [unreadable] [unreadable] [unreadable]..
  42. An Integrated PET-MRI System for Molecular Imaging
    Bernd Pichler; Fiscal Year: 2005
    ..abstract_text> ..
  43. An Integrated CT-based Image-Guided Neurosurgical System
    JOSEPH STAYMAN; Fiscal Year: 2005
    ..for reducing the size of the imager and the effective dosage) but to evaluate the device through clinical trials for the specific task of resection of brain tumors. ..
  44. Helical Pinhole SPECT for Small-Scale Quantification
    SCOTT METZLER; Fiscal Year: 2003
    ..Another long-term vision for this system is its miniaturization to a table-top research instrument. ..
  45. Helical Pinhole SPECT for Small-Scale Quantification
    SCOTT METZLER; Fiscal Year: 2006
    ..Another long-term vision for this system is its miniaturization to a table-top research instrument. [unreadable] [unreadable]..
  46. X-SPECTTM for Functional & Anatomic Imaging In Vivo
    Sissy Jhiang; Fiscal Year: 2006
    ..Thus, space and utilities for the instrument plus the salary and benefits for the research nuclear medicine technologist will be provided by the Ohio State University Comprehensive Cancer Center. [unreadable] [unreadable]..
  47. INTEGRATED 3D DISPLAY OF MR, CT, AND PET IMAGES
    David Levin; Fiscal Year: 1993
    ..Software for surgery simulation will be written so that the user can "rehearse" surgical procedures on the 3-D model...
  48. Novel Extended Red-Shifted Xanthene Dyes
    NICHOLAS CAIRNS; Fiscal Year: 2003
    ..abstract_text> ..
  49. Mathematical Model of Linked Longitudinal Data
    Peter Meyer; Fiscal Year: 2006
    ..The Candidate will develop the necessary skills to be an independent researcher in biostatistics, cardiovascular epidemiology and cardiology through the training and research projects. ..
  50. Animal SPECT camera for functional microimaging of brain
    BRADLEY PATT; Fiscal Year: 2005
    ..The prototype scanner will be capable of non-invasive, internal, in vivo, quantitative functional and fully 3-dimensional imaging of animals from mice to non-human primate brains. ..
  51. NUFFT for Multi-Modality In Vivo Imaging
    Qing Liu; Fiscal Year: 2006
    ..The joint inversion method will improve the information obtained by the individual modalities. ..
  52. INTERACTIVE 3-D ATLAS OF HUMAN TOOTH ANATOMY
    William Brown; Fiscal Year: 2001
    ..We expect that it will currently be a required purchase by the 4200 freshman dental students in the 55 US dental schools. We also expect a large international market. ..
  53. CORONARY ARTERY CALCIUM, EXERCISE TESTS, AND CHD OUTCOME
    MICHAEL LAMONTE; Fiscal Year: 2004
    ..This study will make important contributions as to the role of the primary exposures as predictors of CHD and diabetes. and implications for the prevention of these diseases. ..
  54. DEEP WHITE MATTER LESIONS--IMAGING AND COGNITIVE STUDIES
    Craig Van Dyke; Fiscal Year: 1990
    ..type (SDAT)? In non-demented subjects, is the presence of DWMLs associated with increased risk for developing cognitive impairments over time? What is the neuropathologic basis of the abnormalities we identify with MRI and PET?..
  55. Sub-Millimeter Stimultaneous SPECT-CT for Imaging
    Lawrence MacDonald; Fiscal Year: 2001
    ....
  56. BONE REMODELING IN PAGET'S DISEASE
    Henry Bone; Fiscal Year: 1993
    ..The proposed work will complement, but not duplicate, ongoing studies relating bone structure to biology in other conditions. ..
  57. Determinants of Accelerated CVD in Type 1 Diabetes
    Marian Rewers; Fiscal Year: 2007
    ....
  58. COMPUTED 3D SURFACE AND VOLUME ESTIMATION IN CT AND MRI
    Charles Meyer; Fiscal Year: 1993
    ..The major clinical beneficiaries of substantial success in these algorithm developments are 3D radiation therapy treatment planning and routine and inexpensive quantitative assessment of tumor response to therapy...
  59. QUANTITATIVE MICROTOMOGRAPHY OF BONE TRABECULAE
    Michael Flynn; Fiscal Year: 2003
    ..Prior experience indicates that these models should alter the mineralization and porosity at a microscopic scale. ..
  60. Coronary Artery Calcification in Type 1 Diabetes
    Marian Rewers; Fiscal Year: 2007
    ..This proposed study will better define the causes of increased heart disease risk in T1D patients, develop appropriate screening methods, and set the stage for effective primary prevention. ..
  61. Radiation Dose Reduction in X-ray Computed Tomography
    Bruce Whiting; Fiscal Year: 2002
    ..Accomplishing these objectives will enable us to define a systematic research program for establish clinical dose-reduction protocols. ..
  62. A Novel In-Vivo Cell Tracking System Based on Combined XCT and FT
    William Barber; Fiscal Year: 2009
    ..This new technology will create a new type of dual-modality molecular imaging. This project will create new cell tracking capabilities and will benefit preclinical studies of cellular therapies. ..
  63. Improvement of CT-Based PET Attenuation Correction
    CHARLES LAYMON; Fiscal Year: 2004
    ..This is a far simpler problem than the general case. The results of the proposed research will provide basic tools and experience for developing a comprehensive strategy for optimizing the use of PET/CT data. ..
  64. Image-Guided Chemotherapy and Radiofrequency Ablation
    Agata Exner; Fiscal Year: 2004
    ..abstract_text> ..