computer assisted image interpretation

Summary

Summary: Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.

Top Publications

  1. ncbi Refinements in stress echocardiographic techniques improve inter-institutional agreement in interpretation of dobutamine stress echocardiograms
    R Hoffmann
    Medical Clinic I, University RWTH Aachen, Aachen, Germany
    Eur Heart J 23:821-9. 2002
  2. ncbi A statistical model for contours in images
    Francois Destrempes
    Département d informatique et de recherche opérationnelle, C P 6128, Succ Centre Ville, Montreal, Quebec, Canada, H3C 3J7
    IEEE Trans Pattern Anal Mach Intell 26:626-38. 2004
  3. pmc Image reconstruction in SNR units: a general method for SNR measurement
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 54:1439-47. 2005
  4. ncbi Tissue characterisation using intravascular radiofrequency data analysis: recommendations for acquisition, analysis, interpretation and reporting
    Hector M Garcia-Garcia
    Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    EuroIntervention 5:177-89. 2009
  5. ncbi Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe
    Alexander Hammers
    MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, United Kingdom
    Hum Brain Mapp 19:224-47. 2003
  6. ncbi Sparse MRI: The application of compressed sensing for rapid MR imaging
    Michael Lustig
    Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Stanford, California 94305 9510, USA
    Magn Reson Med 58:1182-95. 2007
  7. ncbi Effects of noise, image resolution, and ROI definition on the accuracy of standard uptake values: a simulation study
    Ronald Boellaard
    PET Center, VU University Medical Center, Amsterdam, The Netherlands
    J Nucl Med 45:1519-27. 2004
  8. doi Long-term global and regional brain volume changes following severe traumatic brain injury: a longitudinal study with clinical correlates
    Annette Sidaros
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
    Neuroimage 44:1-8. 2009
  9. ncbi White matter damage in Alzheimer disease and mild cognitive impairment: assessment with diffusion-tensor MR imaging and parallel imaging techniques
    Robert Stahl
    Department of Clinical Radiology, University Hospitals Grosshadern, Ludwig Maximilians University of Munich, Munich, Germany
    Radiology 243:483-92. 2007
  10. ncbi Normalized cuts in 3-D for spinal MRI segmentation
    Julio Carballido-Gamio
    Joint Graduate Group in Bioengineering, University of California, San Francisco, 94143 1290, USA
    IEEE Trans Med Imaging 23:36-44. 2004

Detail Information

Publications285 found, 100 shown here

  1. ncbi Refinements in stress echocardiographic techniques improve inter-institutional agreement in interpretation of dobutamine stress echocardiograms
    R Hoffmann
    Medical Clinic I, University RWTH Aachen, Aachen, Germany
    Eur Heart J 23:821-9. 2002
    ..To determine the degree of inter-institutional agreement in the assessment of dobutamine stress echocardiograms using modern stress echocardiographic technology in combination with standardized data acquisition and assessment criteria...
  2. ncbi A statistical model for contours in images
    Francois Destrempes
    Département d informatique et de recherche opérationnelle, C P 6128, Succ Centre Ville, Montreal, Quebec, Canada, H3C 3J7
    IEEE Trans Pattern Anal Mach Intell 26:626-38. 2004
    ....
  3. pmc Image reconstruction in SNR units: a general method for SNR measurement
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 54:1439-47. 2005
    ..The procedure includes scaling for noise equivalent bandwidth of digital receivers, FFTs and associated window functions (raw data filters), and array combining...
  4. ncbi Tissue characterisation using intravascular radiofrequency data analysis: recommendations for acquisition, analysis, interpretation and reporting
    Hector M Garcia-Garcia
    Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    EuroIntervention 5:177-89. 2009
    ....
  5. ncbi Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe
    Alexander Hammers
    MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, United Kingdom
    Hum Brain Mapp 19:224-47. 2003
    ..Its potential applications range from the automatic labeling of new scans to the detection of anatomical abnormalities in patients. Further data can be extracted from the atlas for the detailed analysis of individual structures...
  6. ncbi Sparse MRI: The application of compressed sensing for rapid MR imaging
    Michael Lustig
    Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Stanford, California 94305 9510, USA
    Magn Reson Med 58:1182-95. 2007
    ..Examples demonstrate improved spatial resolution and accelerated acquisition for multislice fast spin-echo brain imaging and 3D contrast enhanced angiography...
  7. ncbi Effects of noise, image resolution, and ROI definition on the accuracy of standard uptake values: a simulation study
    Ronald Boellaard
    PET Center, VU University Medical Center, Amsterdam, The Netherlands
    J Nucl Med 45:1519-27. 2004
    ..Therefore, an experimental and simulation study was performed to determine the effects of noise, image resolution, and region-of-interest (ROI) definition on the accuracy of SUVs...
  8. doi Long-term global and regional brain volume changes following severe traumatic brain injury: a longitudinal study with clinical correlates
    Annette Sidaros
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
    Neuroimage 44:1-8. 2009
    ..This indicates that the long-term atrophy is attributable to consequences of traumatic axonal injury. Despite progressive atrophy, remarkable clinical improvement occurred in most patients...
  9. ncbi White matter damage in Alzheimer disease and mild cognitive impairment: assessment with diffusion-tensor MR imaging and parallel imaging techniques
    Robert Stahl
    Department of Clinical Radiology, University Hospitals Grosshadern, Ludwig Maximilians University of Munich, Munich, Germany
    Radiology 243:483-92. 2007
    ....
  10. ncbi Normalized cuts in 3-D for spinal MRI segmentation
    Julio Carballido-Gamio
    Joint Graduate Group in Bioengineering, University of California, San Francisco, 94143 1290, USA
    IEEE Trans Med Imaging 23:36-44. 2004
    ..Results of the segmentation as well as limitations and challenges in this area are presented...
  11. pmc Baseline and longitudinal patterns of brain atrophy in MCI patients, and their use in prediction of short-term conversion to AD: results from ADNI
    Chandan Misra
    Department of Radiology, Section of Biomedical Image Analysis, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA
    Neuroimage 44:1415-22. 2009
    ..These pattern classification schemes, which distill spatial patterns of atrophy to a single abnormality score, offer promise as biomarkers of AD and as predictors of subsequent clinical progression, on an individual patient basis...
  12. doi Diffusion tensor MR imaging and fiber tractography: technical considerations
    P Mukherjee
    Department of Radiology, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    AJNR Am J Neuroradiol 29:843-52. 2008
    ..An overview of current methods for quantitative analysis of DTI data and fiber tractography in clinical research is also provided...
  13. ncbi Anatomically constrained region deformation for the automated segmentation of the hippocampus and the amygdala: Method and validation on controls and patients with Alzheimer's disease
    Marie Chupin
    Department of Clinical and Experimental Epilepsy, Institute of Neurology, UCL, UK
    Neuroimage 34:996-1019. 2007
    ..The proposed approach provides a new framework for further developments in quantitative analyses of the pathological hippocampus and amygdala in MRI scans...
  14. ncbi Two-dimensional strain--a Doppler-independent ultrasound method for quantitation of regional deformation: validation in vitro and in vivo
    Josef Korinek
    Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    J Am Soc Echocardiogr 18:1247-53. 2005
    ..We compared strains measured in vitro and in vivo by 2DSE with those obtained by sonomicrometry...
  15. ncbi Functional MR imaging of prostate cancer
    Young Jun Choi
    Department of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Poong nap dong, Songpa Gu, Seoul 138 736, South Korea
    Radiographics 27:63-75; discussion 75-7. 2007
    ....
  16. pmc Localization accuracy in single-molecule microscopy
    Raimund J Ober
    Department of Electrical Engineering, University of Texas at Dallas, Richardson, Texas, USA
    Biophys J 86:1185-200. 2004
    ..The results demonstrate what is achievable by single-molecule microscopy and provide guidelines for experimental design...
  17. ncbi Increased sensitivity in neuroimaging analyses using robust regression
    Tor D Wager
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Neuroimage 26:99-113. 2005
    ..We show that IRLS can have substantial benefits in analysis of group data and in estimating hemodynamic response shapes from time series data. We provide software to implement IRLS in group neuroimaging analyses...
  18. doi Quantitative 2D and 3D phase contrast MRI: optimized analysis of blood flow and vessel wall parameters
    A F Stalder
    Department of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Freiburg, Germany
    Magn Reson Med 60:1218-31. 2008
    ..Initial results in a patient with atherosclerosis suggest the potential of the method for understanding the formation and progression of cardiovascular diseases...
  19. pmc Human brain white matter atlas: identification and assignment of common anatomical structures in superficial white matter
    Kenichi Oishi
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 43:447-57. 2008
    ..We anticipate that this atlas will be useful resource for atlas-based white matter anatomical studies...
  20. ncbi 18F-FDG PET findings in frontotemporal dementia: an SPM analysis of 29 patients
    Yong Jeong
    Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Nucl Med 46:233-9. 2005
    ..The aim of the current study was 2-fold: (a) to delineate the brain regions with reduction of glucose metabolism, and (b) to investigate the hemispheric asymmetry of glucose metabolism in FTD using (18)F-FDG PET...
  21. pmc Validation of a fully automated 3D hippocampal segmentation method using subjects with Alzheimer's disease mild cognitive impairment, and elderly controls
    Jonathan H Morra
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 1769, USA
    Neuroimage 43:59-68. 2008
    ..Our error metrics compare favorably with those previously reported for other automated hippocampal segmentations, suggesting the utility of the approach for large-scale studies...
  22. ncbi A novel iterative method for lesion delineation and volumetric quantification with FDG PET
    Jorn A van Dalen
    Department of Nuclear Medicine, Radboud University Nijmegen Medical Centre, The Netherlands
    Nucl Med Commun 28:485-93. 2007
    ..A novel, model-based method is hypothesized to provide threshold levels independent f the SBR and to allow accurate measurement of volumes down to the resolution of the PET scanner...
  23. ncbi Accuracy and feasibility of online 3-dimensional echocardiography for measurement of left ventricular parameters
    Carly Jenkins
    University of Queensland, Brisbane, Australia
    J Am Soc Echocardiogr 19:1119-28. 2006
    ..We sought to compare offline and online approaches with magnetic resonance imaging (MRI)...
  24. ncbi The visual word form area and the frequency with which words are encountered: evidence from a parametric fMRI study
    Martin Kronbichler
    Department of Psychology, University of Salzburg, Austria
    Neuroimage 21:946-53. 2004
    ..This convergence suggests that fusiform regions are specialized for extracting and storing abstract patterns when processing visual objects and these patterns serve as recognition units in subsequent encounters with the same objects...
  25. pmc Spatial normalization of lesioned brains: performance evaluation and impact on fMRI analyses
    Jenny Crinion
    Wellcome Trust Centre for Neuroimaging, UCL, 12 Queen Square, London WC1N 3BG, UK
    Neuroimage 37:866-75. 2007
    ..This has important implications for users of both structural and functional imaging techniques in the study of patients with structural brain damage...
  26. doi Heterogeneity of white matter hyperintensities in Alzheimer's disease: post-mortem quantitative MRI and neuropathology
    A A Gouw
    Department of Neurology, Alzheimer Center and Image Analysis Center, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Brain 131:3286-98. 2008
    ..Quantitative MRI techniques reveal differences in WMH between Alzheimer's disease and non-demented elderly, and are able to reflect the severity of the neuropathological changes involved...
  27. ncbi Parameter-optimized digital holographic microscope for high-resolution living-cell analysis
    Daniel Carl
    Laboratory of Biophysics, University of Munster, Robert Koch Strasse 45, D 48129 Munster, Germany
    Appl Opt 43:6536-44. 2004
    ..The lateral and the axial resolutions of the system are discussed and quantified by application to technical objects and to living cells...
  28. ncbi Rigid registration of 3-D ultrasound with MR images: a new approach combining intensity and gradient information
    A Roche
    INRIA Projet Epidaure, Sophia Antipolis, France
    IEEE Trans Med Imaging 20:1038-49. 2001
    ..A cross-validation study has been carried out using a number of phantom and clinical data. This indicates that the method is quite robust and that the worst registration errors are of the order of the MR image resolution...
  29. ncbi Reconstruction and visualization of fiber and laminar structure in the normal human heart from ex vivo diffusion tensor magnetic resonance imaging (DTMRI) data
    Damien Rohmer
    Life Sciences Division, Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, California, USA
    Invest Radiol 42:777-89. 2007
    ..The purpose of this study is the reconstruction and visualization of these structures in 3 dimensions...
  30. ncbi Imaging features that discriminate between foci induced by high- and low-LET radiation in human fibroblasts
    Sylvain V Costes
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Radiat Res 165:505-15. 2006
    ..Thus, even though double-strand breaks and radiation-induced foci are correlated, the dynamic nature of both contradicts their accepted equivalence for low doses of different radiation qualities...
  31. ncbi The current status of breast MR imaging. Part I. Choice of technique, image interpretation, diagnostic accuracy, and transfer to clinical practice
    Christiane Kuhl
    Department of Radiology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
    Radiology 244:356-78. 2007
    ....
  32. ncbi Textural analysis of contrast-enhanced MR images of the breast
    Peter Gibbs
    Academic Department of Radiology, University of Hull, Hull, United Kingdom
    Magn Reson Med 50:92-8. 2003
    ..On combining features obtained using textural analysis with lesion size, time to maximum enhancement, and patient age, a diagnostic accuracy of A(z) = 0.92 +/- 0.05 was demonstrated...
  33. ncbi Bayesian fMRI data analysis with sparse spatial basis function priors
    Guillaume Flandin
    Wellcome Department of Imaging Neuroscience, 12 Queen Square, London WC1N 3BG, UK
    Neuroimage 34:1108-25. 2007
    ..Results are shown on synthetic data and on data from an event-related fMRI experiment...
  34. doi Assessment of fluctuating velocities in disturbed cardiovascular blood flow: in vivo feasibility of generalized phase-contrast MRI
    Petter Dyverfeldt
    Division of Cardiovascular Medicine, Department of Medical and Health Sciences, Linkoping University, Linkoping, Sweden
    J Magn Reson Imaging 28:655-63. 2008
    ..To evaluate the feasibility of generalized phase-contrast magnetic resonance imaging (PC-MRI) for the noninvasive assessment of fluctuating velocities in cardiovascular blood flow...
  35. pmc Late gadolinium enhancement: precursor to cardiomyopathy in Duchenne muscular dystrophy?
    Michael D Puchalski
    Department of Pediatrics, University of Utah and Primary Children s Medical Center, 100 N Medical Drive, Salt Lake City, UT 84113, USA
    Int J Cardiovasc Imaging 25:57-63. 2009
    ....
  36. ncbi Regional frontal cortical volumes decrease differentially in aging: an MRI study to compare volumetric approaches and voxel-based morphometry
    Danielle J Tisserand
    Brain and Behaviour Institute, Maastricht University, 6229 GP Maastricht, The Netherlands
    Neuroimage 17:657-69. 2002
    ..Overall, it was concluded that although semiautomated and voxel-based methods can provide a reasonable estimate of regional brain volume, they cannot serve as a substitute for manual volumetry...
  37. ncbi Transit of blood flow through the human left ventricle mapped by cardiovascular magnetic resonance
    Ann F Bolger
    Department of Medicine, University of California, San Francisco, California 94110, USA
    J Cardiovasc Magn Reson 9:741-7. 2007
    ..Quantification of the components of multidirectional flow in the normal left ventricle (LV) is lacking, making it difficult to put the changes observed with LV dysfunction and cardiac surgery into context...
  38. ncbi Multilevel linear modelling for FMRI group analysis using Bayesian inference
    Mark W Woolrich
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK
    Neuroimage 21:1732-47. 2004
    ..We also demonstrate that we can infer on the top level of multilevel hierarchies by inferring on the levels of the hierarchy separately and passing summary statistics of a noncentral multivariate t distribution between them...
  39. doi Effectiveness of a noninvasive digital infrared thermal imaging system in the detection of breast cancer
    Nimmi Arora
    Department of Surgery, New York Presbyterian Hospital Cornell, New York, NY, USA
    Am J Surg 196:523-6. 2008
    ..Digital infrared thermal imaging (DITI) has resurfaced in this era of modernized computer technology. Its role in the detection of breast cancer is evaluated...
  40. doi Measurement of myocardial frequency offsets during first pass of a gadolinium-based contrast agent in perfusion studies
    Pedro Ferreira
    National Heart and Lung Institute, Imperial College, London, UK
    Magn Reson Med 60:860-70. 2008
    ..However, when added to other sources of off-resonance it can cause dark rims in particular regions of the myocardium wall in balanced-SSFP sequences...
  41. ncbi Segmentation of 4D cardiac MR images using a probabilistic atlas and the EM algorithm
    Maria Lorenzo-Valdés
    Visual Information Processing Group, Department of Computing, Imperial College London, 180 Queens Gate, London SW7 2BZ, UK
    Med Image Anal 8:255-65. 2004
    ..93) and myocardium (0.94) when the atlas constructed with volunteers is blurred...
  42. doi Apparent diffusion coefficient values in peripheral and transition zones of the prostate: comparison between normal and malignant prostatic tissues and correlation with histologic grade
    Tsutomu Tamada
    Department of Radiology, Kawasaki Medical School, Okayama, Japan
    J Magn Reson Imaging 28:720-6. 2008
    ....
  43. doi Navigator-gated 3D blood oxygen level-dependent CMR at 3.0-T for detection of stress-induced myocardial ischemic reactions
    Cosima Jahnke
    Department of Internal Medicine Cardiology, German Heart Institute, Berlin, Germany
    JACC Cardiovasc Imaging 3:375-84. 2010
    ..This study determined the value of navigator-gated 3-dimensional blood oxygen level-dependent (BOLD) cardiac magnetic resonance (CMR) at 3.0-T for the detection of stress-induced myocardial ischemic reactions...
  44. doi Computer-aided diagnosis of Alzheimer's disease using support vector machines and classification trees
    D Salas-Gonzalez
    Department of Signal Theory Networking and Communications, ETSIIT, University of Granada, Spain
    Phys Med Biol 55:2807-17. 2010
    ..They are chosen as feature vectors for two different classifiers: support vector machines with linear kernel and classification trees. The proposed methodology reaches greater than 95% accuracy in the classification task...
  45. ncbi Malignant-lesion segmentation using 4D co-occurrence texture analysis applied to dynamic contrast-enhanced magnetic resonance breast image data
    Brent J Woods
    Department of Electrical and Computer Engineering, Ohio State University, Columbus, Ohio 43210, USA
    J Magn Reson Imaging 25:495-501. 2007
    ..To investigate the use of four-dimensional (4D) co-occurrence-based texture analysis to distinguish between nonmalignant and malignant tissues in dynamic contrast-enhanced (DCE) MR images...
  46. pmc The relationship between diffusion tensor imaging and volumetry as measures of white matter properties
    Anders M Fjell
    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Norway
    Neuroimage 42:1654-68. 2008
    ..Further, FA and WM volume are moderately to weakly related and to a large extent sensitive to different characteristics of WM integrity...
  47. doi VBM anticipates the rate of progression of Alzheimer disease: a 3-year longitudinal study
    S Kinkingnehun
    INSERM U610, Paris, France
    Neurology 70:2201-11. 2008
    ..To determine whether regional atrophy or neuropsychological factors can predict the rate of decline in patients with mild Alzheimer disease (AD)...
  48. ncbi Variation of BOLD hemodynamic responses across subjects and brain regions and their effects on statistical analyses
    Daniel A Handwerker
    Henry H Wheeler Jr Brain Imaging Center, Helen Wills Neuroscience Institute and Department of Psychology, University of California, Berkeley, CA 94720, USA
    Neuroimage 21:1639-51. 2004
    ..These results highlight the benefits of determining the best possible HRF estimate and potential negative consequences of assuming HRF consistency across subjects or brain regions...
  49. ncbi Direct comparison of myocardial perfusion cardiovascular magnetic resonance sequences with parallel acquisition
    Jonathan C Lyne
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    J Magn Reson Imaging 26:1444-51. 2007
    ..To directly compare the three main myocardial perfusion cardiovascular magnetic resonance (CMR) sequences incorporating parallel acquisition methods...
  50. ncbi Atlas renormalization for improved brain MR image segmentation across scanner platforms
    Xiao Han
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    IEEE Trans Med Imaging 26:479-86. 2007
    ....
  51. pmc Biexponential characterization of prostate tissue water diffusion decay curves over an extended b-factor range
    Robert V Mulkern
    Department of Radiology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Magn Reson Imaging 24:563-8. 2006
    ....
  52. ncbi Computational methods for analysis of human breast tumor tissue in optical coherence tomography images
    Adam M Zysk
    Department of Electrical and Computer Engineering, University of Illinois at Urbana Champaign, Beckman Institute for Advanced Science and Technology, 405 N Mathews Ave, Urbana, Illinois 61801, USA
    J Biomed Opt 11:054015. 2006
    ..Derived from preliminary OCT data, these methods are aimed at the development of automated diagnostic tools that will aid in the translation of this technology into the clinical environment...
  53. ncbi Attenuation correction in myocardial perfusion SPECT/CT: effects of misregistration and value of reregistration
    Sibyll Goetze
    Division of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA
    J Nucl Med 48:1090-5. 2007
    ..Misregistration will influence regional tracer distribution and may reduce diagnostic accuracy. This study focused on the role of misregistration in cardiac SPECT/CT and the performance of a software-based approach for reregistration...
  54. ncbi Differentiating benign from malignant solid breast masses with US strain imaging
    Elizabeth S Burnside
    Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, Madison, WI 53792 3252, USA
    Radiology 245:401-10. 2007
    ..To prospectively evaluate the sensitivity and specificity of ultrasonographic (US) strain imaging for distinguishing between benign and malignant solid breast masses, with biopsy results as the reference standard...
  55. ncbi Voxel-based detection of white matter abnormalities in mild Alzheimer disease
    S Xie
    Radiology Department, Peking University First Hospital, 8 Xishiku St, Xicheng District, Beijing, 100034, China
    Neurology 66:1845-9. 2006
    ..To detect white matter abnormalities in patients with mild Alzheimer disease (AD) by diffusion tensor imaging and to determine their topographic relationship with gray matter atrophy...
  56. pmc A population-average MRI-based atlas collection of the rhesus macaque
    Donald G McLaren
    Geriatric Research Education and Clinical Center, Wm S Middleton Memorial Veterans Hospital, Madison, WI 53705, USA
    Neuroimage 45:52-9. 2009
    ..It is anticipated that these tools will help facilitate voxel-based imaging methodologies in non-human primate species, which in turn may increase our understanding of brain function, development, and evolution...
  57. ncbi Fast high-resolution T1 mapping of the human brain
    Ralf Deichmann
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, London, UK
    Magn Reson Med 54:20-7. 2005
    ..In addition, an improved fitting algorithm based on smoothed flip angle maps is presented and tested successfully...
  58. ncbi Potential and feasibility of parallel MRI at high field
    Florian Wiesinger
    Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland
    NMR Biomed 19:368-78. 2006
    ..In further sections, technical challenges and practical aspects are discussed. The feasibility of parallel MRI at ultra-high field is illustrated by current results of parallel human MRI at 7 T...
  59. ncbi Automated 3-dimensional elastic registration of whole-body PET and CT from separate or combined scanners
    Raj Shekhar
    Department of Diagnostic Radiology, University of Maryland, Baltimore, MD 21201, USA
    J Nucl Med 46:1488-96. 2005
    ..Although a combined PET/CT scanner removes many of these misalignments, breathing-related nonrigid mismatches still persist...
  60. doi Characterization of breast cancer types by texture analysis of magnetic resonance images
    Kirsi Holli
    Medical Imaging Centre, Tampere University Hospital, Post Box 2000, 33521 Tampere, Finland
    Acad Radiol 17:135-41. 2010
    ....
  61. pmc Independent histogram pursuit for segmentation of skin lesions
    David Delgado Gómez
    Computational Imaging Lab, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain
    IEEE Trans Biomed Eng 55:157-61. 2008
    ..The boundary detection precision using k-means segmentation was close to 97%. The proposed algorithm can be easily combined with the majority of classification algorithms...
  62. doi Unenhanced MR angiography of the thoracic aorta: initial clinical evaluation
    Christopher J Francois
    Department of Radiology, Northwestern University, Chicago, IL, USA
    AJR Am J Roentgenol 190:902-6. 2008
    ....
  63. pmc Cardiovascular magnetic resonance parameters of atherosclerotic plaque burden improve discrimination of prior major adverse cardiovascular events
    Venkatesh Mani
    Imaging Science Laboratories Translational and Molecular Imaging Institute, Department of Radiology, Mount Sinai School of Medicine, New York, NY, USA
    J Cardiovasc Magn Reson 11:10. 2009
    ..The purpose of this study was to determine if patients with traditional risk factors and prior MACE had increased cardiovascular magnetic resonance (CMR) plaque burden measures compared to patients with risk factors but no prior events...
  64. ncbi Automatic contour propagation in cine cardiac magnetic resonance images
    Gilion Hautvast
    Advanced Development Department, Philips Medical Systems Healthcare Informatics, 5680 DA Best, The Netherlands
    IEEE Trans Med Imaging 25:1472-82. 2006
    ..Consequently, the resulting contours can be used to accurately determine physiological parameters such as stroke volume and ejection fraction...
  65. pmc Quantitative analysis of lesion morphology and texture features for diagnostic prediction in breast MRI
    Ke Nie
    Tu and Yuen Center for Functional Onco Imaging, University of California, CFOI, 164 Irvine Hall, Irvine, CA 92697, USA
    Acad Radiol 15:1513-25. 2008
    ....
  66. ncbi Quantifying the spatial resolution of the gradient echo and spin echo BOLD response at 3 Tesla
    Laura M Parkes
    F C Donders Centre for Cognitive Neuroimaging, University of Nijmegen, The Netherlands
    Magn Reson Med 54:1465-72. 2005
    ..The spin echo response shows a 13% reduction in the width of the PSF, but at a cost of at least 3-fold reduction in contrast to noise ratio...
  67. ncbi Prostate cancer multi-feature analysis using trans-rectal ultrasound images
    S S Mohamed
    Electrical and Computer Engineering Department, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada
    Phys Med Biol 50:N175-85. 2005
    ..The accuracy classification results range from 87.5% to 93.75%, where the performance of the SVM and that of the DT are significantly better than the performance of the CNN...
  68. ncbi Signal and noise characteristics of Hahn SE and GE BOLD fMRI at 7 T in humans
    Essa Yacoub
    Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Neuroimage 24:738-50. 2005
    ..It was concluded that HSE imaging yields a significantly reduced amount of nonspecific signals compared to GE imaging, and, would be the method of choice (over GE) for high-resolution applications in humans...
  69. pmc Automated MRI measures identify individuals with mild cognitive impairment and Alzheimer's disease
    Rahul S Desikan
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Brain 132:2048-57. 2009
    ....
  70. ncbi Automated segmentation, classification, and tracking of cancer cell nuclei in time-lapse microscopy
    Xiaowei Chen
    HCNR Center for Bioinformatics, Harvard Medical School, Boston, MA 02115, USA
    IEEE Trans Biomed Eng 53:762-6. 2006
    ..Experimental results show that the proposed method is efficient and effective in cell tracking and phase identification...
  71. ncbi Biphasic tissue Doppler waveforms during isovolumic phases are associated with asynchronous deformation of subendocardial and subepicardial layers
    Partho P Sengupta
    Division of Cardiovascular Diseases, Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905, USA
    J Appl Physiol 99:1104-11. 2005
    ..The results support an association between asynchronous deformation of subendocardial and subepicardial muscle fibers and the biphasic isovolumic movements observed with high-resolution tissue Doppler imaging...
  72. ncbi Digital holographic microscopy: a noninvasive contrast imaging technique allowing quantitative visualization of living cells with subwavelength axial accuracy
    Pierre Marquet
    Department of Physiology, University of Lausanne, CH 1005 Lausanne, Switzerland
    Opt Lett 30:468-70. 2005
    ..These DHM images are compared with those obtained by use of the widely used phase contrast and Nomarski differential interference contrast techniques...
  73. doi Contrast-enhanced whole-heart coronary magnetic resonance angiography at 3.0 T: comparison with steady-state free precession technique at 1.5 T
    Xin Liu
    Department of Radiology, Northwestern University, Chicago, Illinois 60611, USA
    Invest Radiol 43:663-8. 2008
    ..To compare contrast-enhanced whole-heart coronary MR angiography (MRA) at 3.0 T and noncontrast steady-state free precession coronary MRA at 1.5 T in the same volunteers...
  74. ncbi A new algorithm for border description of polarized light surface microscopic images of pigmented skin lesions
    Costantino Grana
    Department of Computer Engineering, University of Modena and Reggio Emilia, 41100 Modena, Italy
    IEEE Trans Med Imaging 22:959-64. 2003
    ..The efficacy of these new descriptors was tested on a data set of 510 pigmented skin lesions, composed by 85 melanomas and 425 nevi, by employing statistical methods for discrimination between the two populations...
  75. doi In vivo quantification of carotid artery wall dimensions: 3.0-Tesla MRI versus B-mode ultrasound imaging
    R Duivenvoorden
    Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Circ Cardiovasc Imaging 2:235-42. 2009
    ..Our aim was to compare common carotid mean wall thickness (MWT) measurements by 3.0-T MRI with B-mode ultrasound common carotid intima-media thickness (CCIMT) measurements, a validated surrogate marker for cardiovascular disease...
  76. ncbi Investigating cervical spinal cord structure using axial diffusion tensor imaging
    Claudia A M Wheeler-Kingshott
    NMR Research Unit, University Department of Clinical Neurology, Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, United Kingdom
    Neuroimage 16:93-102. 2002
    ..The high axial resolution allowed preliminary evaluation of fiber connectivity using the fast-marching tractography algorithm, which generated traces of fiber paths consistent with the well-known cord anatomy...
  77. doi Can voxel based morphometry, manual segmentation and automated segmentation equally detect hippocampal volume differences in acute depression?
    Loretxu Bergouignan
    CNRS UMR, Emotion Center, Department of Psychiatry, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Neuroimage 45:29-37. 2009
    ..Few studies used automated methods such as voxel-based morphometry (VBM) or automated segmentation that can overcome certain drawbacks of manual segmentation (essentially intra- and inter-rater variability and operator time consumption)...
  78. pmc Ex vivo 3D diffusion tensor imaging and quantification of cardiac laminar structure
    Patrick A Helm
    Center for Cardiovascular Bioinformatics and Modeling, Johns Hopkins University, Baltimore, MD 21218, USA
    Magn Reson Med 54:850-9. 2005
    ....
  79. ncbi Addition of the long-axis information to short-axis contours reduces interstudy variability of left-ventricular analysis in cardiac magnetic resonance studies
    Sharon W Kirschbaum
    Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands
    Invest Radiol 43:1-6. 2008
    ..To reduce interstudy variability using long-axis information for correcting short-axis (SA) contours at basal and apical level for left-ventricular analysis by magnetic resonance imaging...
  80. doi Whole-body magnetic resonance angiography at 3 tesla using a hybrid protocol in patients with peripheral arterial disease
    Yousef W Nielsen
    Department of Radiology, University Hospital at Herlev, Herlev Ringvej 75, Copenhagen, Denmark
    Cardiovasc Intervent Radiol 32:877-86. 2009
    ..02 and p = 0.01, observers 1 and 2). In conclusion, hybrid-protocol WB-MRA shows a better diagnostic performance than standard protocol WB-MRA at 3 T in patients with PAD...
  81. pmc Transmural myocardial strain in mouse: quantification of high-resolution MR tagging using harmonic phase (HARP) analysis
    Jia Zhong
    Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44122, USA
    Magn Reson Med 61:1368-73. 2009
    ..3 mm. The proposed method was applied to the quantification of transmural myocardial wall strain in seven normal C57BL/6 mice. Principal strains, as well as radial and circumferential strains, were quantified using the current method...
  82. pmc MRI-derived measurements of human subcortical, ventricular and intracranial brain volumes: Reliability effects of scan sessions, acquisition sequences, data analyses, scanner upgrade, scanner vendors and field strengths
    Jorge Jovicich
    Center for Mind Brain Sciences, Department of Cognitive and Education Sciences, University of Trento, Italy
    Neuroimage 46:177-92. 2009
    ..The results derived from the young groups (scanner upgrade effects and B1 inhomogeneity correction effects) should be considered as preliminary and in need for further validation with a larger dataset...
  83. pmc How well does structural equation modeling reveal abnormal brain anatomical connections? An fMRI simulation study
    Jieun Kim
    Brain Imaging and Modeling Section, National Institute on Deafness and Other Communication Disorders, Bldg 10, Rm 8S235, MSC 1407, National Institutes of Health, Bethesda, MD 20892, USA
    Neuroimage 45:1190-8. 2009
    ....
  84. pmc Variability of myocardial perfusion dark rim Gibbs artifacts due to sub-pixel shifts
    Pedro Ferreira
    National Heart and Lung Institute, Imperial College, London, UK
    J Cardiovasc Magn Reson 11:17. 2009
    ..This article also demonstrates the consequences for Gibbs artifacts when two different methods of image interpolation are applied (post-FFT interpolation, and pre-FFT zero-filling)...
  85. doi Profile order and time-dependent artifacts in contrast-enhanced coronary MR angiography at 3T: origin and prevention
    Melanie S Kotys
    National Heart, Lung, and Blood Institute NHLBI, National Institutes of Health NIH, Bethesda, Maryland 20892 2281, USA
    Magn Reson Med 62:292-9. 2009
    ..Acquisition during the brief postinfusion steady-state produces the greatest signal enhancement and minimizes k-space filtering artifacts...
  86. doi Improved correction of spatial inhomogeneities of surface coils in quantitative analysis of first-pass myocardial perfusion imaging
    Frans P P J Kremers
    Department of Physics, ICaR VU, VU University Medical Center, Amsterdam, The Netherlands
    J Magn Reson Imaging 31:227-33. 2010
    ..This is of importance, as quantitative analysis of magnetic resonance (MR) myocardial perfusion using deconvolution with the arterial input assumes equal signal sensitivity over the heart...
  87. pmc Context based mixture model for cell phase identification in automated fluorescence microscopy
    Meng Wang
    Center for Bioinformatics, Harvard Center for Neurodegeneration and Repair, Harvard Medical School, 3rd Floor, 1249 Boylston, Boston, MA 02215, USA
    BMC Bioinformatics 8:32. 2007
    ..Existing methods are limited in dealing with such time-lapse data sets while manual analysis is not feasible. This paper presents statistical data analysis and statistical pattern recognition to perform this task...
  88. doi Comparison of Alzheimer's disease with vascular dementia and non-dementia using specific voxel-based Z score maps
    Shirou Ishii
    Department of Radiology, Fukusuhima Medical University Hospital, 1 Hikarigaoka, Fukushima, 960 1295, Japan
    Ann Nucl Med 23:25-31. 2009
    ..for the diagnosis of very early AD...
  89. pmc Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning
    Thouis R Jones
    The Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA
    Proc Natl Acad Sci U S A 106:1826-31. 2009
    ..By using this approach, we successfully scored images in RNA interference screens in 2 organisms for the prevalence of 15 diverse cellular morphologies, some of which were previously intractable...
  90. pmc Border detection in dermoscopy images using statistical region merging
    M Emre Celebi
    Department of Computer Science, Louisiana State University in Shreveport, Shreveport, LA 71115, USA
    Skin Res Technol 14:347-53. 2008
    ..Automated border detection is one of the most important steps in this procedure, because the accuracy of the subsequent steps crucially depends on it...
  91. ncbi Early 18F-FDG PET for prediction of prognosis in patients with diffuse large B-cell lymphoma: SUV-based assessment versus visual analysis
    Chieh Lin
    Department of Radiology, H Mondor Hospital, AP HP Paris 12 University, Creteil, France
    J Nucl Med 48:1626-32. 2007
    ..The purpose of this study was to assess the prognostic value of early (18)F-FDG PET using standardized uptake value (SUV) compared with visual analysis in patients with diffuse large B-cell lymphoma (DLBCL)...
  92. doi First-pass dynamic contrast-enhanced MRI with extravasating contrast reagent: evidence for human myocardial capillary recruitment in adenosine-induced hyperemia
    Xin Li
    Advanced Imaging Research Center, Oregon Health and Science University, Portland, OR 97239, USA
    NMR Biomed 22:148-57. 2009
    ..The v(b) values also increased in hyperemia and showed a flow-dependence with a clearly identifiable component due to capillary recruitment...
  93. doi A quantitative evaluation of cross-participant registration techniques for MRI studies of the medial temporal lobe
    Michael A Yassa
    Center for Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, California 92697, USA
    Neuroimage 44:319-27. 2009
    ..The best performance is achieved when both methods are combined. We note that these conclusions are not limited to the MTL and are easily extendable to other areas of the brain...
  94. doi Influence of RF spoiling on the stability and accuracy of T1 mapping based on spoiled FLASH with varying flip angles
    C Preibisch
    Brain Imaging Center, University Hospital, Frankfurt, Germany
    Magn Reson Med 61:125-35. 2009
    ..An algorithm is presented that allows for the calculation of corrected T(1) maps from the apparent values. The method is tested both in phantom experiments and in vivo by acquiring whole-brain T(1) maps of the human brain...
  95. doi Magnetic resonance imaging quantification of left ventricular dysfunction following coronary microembolization
    Marcus Carlsson
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94134, USA
    Magn Reson Med 61:595-602. 2009
    ..It also changed LV geometry and decreased radial and circumferential strain over the course of 1 week...
  96. ncbi Fast tracking of cardiac motion using 3D-HARP
    Li Pan
    Department of Biomedical Engineering, Johns Hopkins School of Medicine, 601 N Caroline St JHOC 4240, Baltimore, MD 21287, USA
    IEEE Trans Biomed Eng 52:1425-35. 2005
    ..8605 and r2 = 0.8645, respectively. The total time required for tracking 3-D cardiac motion is approximately 10 min in a 9 timeframe tagged MRI dataset and has the potential to be much faster...
  97. doi Use of fractional anisotropy for determination of the cut-off value in 11C-methionine positron emission tomography for glioma
    Manabu Kinoshita
    Department of Neurosurgery, Osaka University Gradate School of Medicine, 2 2 Yamadoka, Suita, Osaka 565 0871, Japan
    Neuroimage 45:312-8. 2009
    ..We propose that the combined analysis of DTI and 11C-methionine PET has the potential to improve tumor border imaging in glioma patients, providing important information for establishing neurosurgical strategies...
  98. doi Quantitative MRI predicts long-term structural and functional outcome after experimental traumatic brain injury
    Riikka J Immonen
    Department of Neurobiology, A I Virtanen Institute for Molecular Sciences, University of Kuopio, Finland
    Neuroimage 45:1-9. 2009
    ..01), and also with the water maze performance (p<0.01). We conclude that, assessment of early quantitative MRI changes in the hippocampus and in the perifocal area may help to predict the long-term outcome after experimental TBI...
  99. doi Multiscale structural analysis of mouse lingual myoarchitecture employing diffusion spectrum magnetic resonance imaging and multiphoton microscopy
    Terry A Gaige
    Massachusetts Institute of Technology, Department of Mechanical and Biological Engineering, Cambridge, Massachusetts 02139, USA
    J Biomed Opt 13:064005. 2008
    ....
  100. doi Computing average shaped tissue probability templates
    John Ashburner
    Wellcome Trust Centre for Neuroimaging, 12 Queen Square, London, WC1N 3BG, UK
    Neuroimage 45:333-41. 2009
    ..g. grey and white matter) are registered simultaneously with the current template estimate. In order to generalise the resulting template to a broader range of subjects, a template blurriness prior is included within the model...
  101. ncbi Operator induced variability in left ventricular measurements with cardiovascular magnetic resonance is improved after training
    Theodoros D Karamitsos
    Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford Centre for Clinical Magnetic Resonance Research, Oxford, UK
    J Cardiovasc Magn Reson 9:777-83. 2007
    ..The aim of the study was to assess the interobserver variability of the manual planimetry of LV contours amongst two experienced and six inexperienced operators before and after a two months training period...

Research Grants116 found, 100 shown here

  1. In Vivo Analysis of the Mechanisms of Neural Crest Migration
    Paul M Kulesa; Fiscal Year: 2010
    ....
  2. Neuroanatomical endophenotypes in Persistent Developmental Stuttering
    Matthew Cykowski; Fiscal Year: 2007
    ..It is known to have a genetic basis, but the genes involved are still largely unknown. Understanding the genetic basis of the disorder will help improve diagnostic approaches and treatment strategies. ..
  3. Very-High-Frequency Ultrasound Imaging With Coded Signals and Annular Arrays
    Jonathan Mamou; Fiscal Year: 2007
    ..It will allow obtaining medical images with exquisite resolution, increased depth of field and a greater depth of penetration, and lead to new capabilities for improved diagnostic imaging and disease management. ..
  4. New Scanning Methods for 3-D Breast Ultrasound
    Jesse Yen; Fiscal Year: 2006
    ..A series of water tank and tissue phantom experiments will be performed to evaluate imaging performance in terms of resolution, contrast, and signal-to-noise ratio. ..
  5. Statistical Analysis of Biomedical Imaging Data in Curved Space
    Hongtu Zhu; Fiscal Year: 2011
    ..New statistical methods are developed and applied to detect morphological differences of cortical and subcortical structures across time between schizophrenia and autism patients and healthy subjects. ..
  6. Diffusion Tensor Imaging of Wallerian Degeneration in MS
    Khader Hasan; Fiscal Year: 2009
    ..The DTI measures, after accounting for the age and gender dependence will be correlated with the clinical measures. ..
  7. Observer Studies Involving Search: Modeling and Analysis
    Dev Chakraborty; Fiscal Year: 2007
    ..Also, the explicit modeling of search and the ability to estimate search related parameters from observer data should open up new areas of vision research that all researchers can exploit. ..
  8. Data Coordinating and Image Analysis for CRISP-II
    Kyongtae Bae; Fiscal Year: 2006
    ....
  9. Study of individual variability in acupuncture and placebo analgesia
    Jian Kong; Fiscal Year: 2007
    ..This integrated program of training and research will yield new tools for studying acupuncture and placebo treatment and provide the candidate with the skills needed to achieve independence in a highly complex field. ..
  10. Diffusion Tensor Imaging of Wallerian Degeneration in MS
    Khader Hasan; Fiscal Year: 2007
    ..This tool will also help in the fusion of multi-modal MRI data for a robust segmentation of the subregions of CC and 1C. The DTI measures, after accounting for the age and gender dependence will be correlated with the clinical measures. ..
  11. Magnetic Resonance Imaging of Cardiomyocyte Apoptosis
    David Sosnovik; Fiscal Year: 2007
    ..The proposed research also has the potential to facilitate a greater understanding of cardiomyocyte apoptosis and accelerate the development of novel cardioprotective strategies. ..
  12. Improved MRI techniques for measurement of absolute temperature distributions
    NICHOLAS TODD; Fiscal Year: 2007
    ..A temporally constrained reconstruction algorithm has been shown to be capable of reducing scan time and can also be implemented with any pulse sequence. ..
  13. Continued Development and Maintenance of a Computational Morphometry Toolkit
    Torsten Rohlfing; Fiscal Year: 2009
    ..This project will enhance a proven soft- ware system for imaging-based morphometric studies and make it freely avail- able to the scientific community. ..
  14. BREATH HOLD 3D MRA OF THE CORONARY ARTERIES
    Robert Edelman; Fiscal Year: 2002
    ..The goal is to optimize the MRA method and to determine if the use of contrast agents provides any clinical benefit. ..
  15. Statistical Analysis of Biomedical Imaging Data in Curved Space
    Hongtu Zhu; Fiscal Year: 2010
    ..New statistical methods are developed and applied to detect morphological differences of cortical and subcortical structures across time between schizophrenia and autism patients and healthy subjects. ..
  16. Identifying CT Imaging Biomarkers Associated with Prognosis of Pulmonary Embolism
    Kyongtae T Bae; Fiscal Year: 2010
    ..We believe the proposed study is timely and will provide a new insight to prognosis and clinical management and treatment of PE. ..
  17. 3-D Transrectal Ultrasound with 2-D Arrays
    JESSE T P YEN; Fiscal Year: 2010
    ..Lastly, a small number of in vitro experiments of canine prostates will be done. ..
  18. New Methods for Analysis of Eye-tracking Data for Medical Image Perception Resear
    Dev P Chakraborty; Fiscal Year: 2010
    ..We propose a new approach to the analysis of eye-tracking data. With better understanding of image perception we will be better able to improve radiologist performance and reduce interpretive errors. ..
  19. Continued Development and Maintenance of a Computational Morphometry Toolkit
    Torsten Rohlfing; Fiscal Year: 2010
    ..This project will enhance a proven soft- ware system for imaging-based morphometric studies and make it freely avail- able to the scientific community. ..
  20. Molecular and Microstructural Imaging of Cardiomyocyte Apoptosis and Autophagy
    David E Sosnovik; Fiscal Year: 2010
    ..The development of such strategies has the potential to significantly reduce the rapidly rising number of patients with heart failure, and is thus of major clinical and public health significance. ..
  21. Pathogenesis and Pathophysiological Mechanisms of Myofascial Trigger Points
    Siddhartha Sikdar; Fiscal Year: 2010
    ..Our approach would also be broadly applicable to elucidating the underlying mechanisms in other chronic musculoskeletal pain disorders, such low back pain. ..
  22. Identifying CT Imaging Biomarkers Associated with Prognosis of Pulmonary Embolism
    Kyongtae Bae; Fiscal Year: 2009
    ..We believe the proposed study is timely and will provide a new insight to prognosis and clinical management and treatment of PE. ..
  23. MR Diffusion Tensor Imaging for Detection and Characterization of Breast Lesions
    SAVANNAH CORRINA PARTRIDGE; Fiscal Year: 2010
    ....
  24. PERCEPTUAL MODEL FOR WORKSTATION DISPLAY OPTIMIZATION
    Dev Chakraborty; Fiscal Year: 2003
    ..Also to be generated are iso-contour plots of the effects of common workstation variables on image quality in both tasks. This will allow digital mammography workstations to be more intelligently used. ..
  25. Smash Contrast-Enhanced 3D MR Angiography
    Robert Edelman; Fiscal Year: 2003
    ....
  26. Observer Studies Involving Search: Modeling and Analysis
    Dev P Chakraborty; Fiscal Year: 2010
    ..Health care benefits because more efficient and cost-effective studies become possible which could serve as surrogates for expensive clinical trials. ..
  27. Preventing spike-wave epileptogenesis: critical periods & neuroimaging biomarkers
    Hal Blumenfeld; Fiscal Year: 2010
    ..untreated animals. We will also investigate the anatomical basis of white matter DTI abnormalities through electron microscopy to determine changes in axons and myelin in affected regions. 2. ..
  28. MIPS XII Conference
    Elizabeth Krupinski; Fiscal Year: 2007
    ....
  29. Tools for Analyzing Cortical Structure and Connectivity
    Bruce Fischl; Fiscal Year: 2010
    ..abstract_text> ..
  30. PARTNERSHIP FOR MR SPECTROSCOPIC IMAGING DATA PROCESSING
    ANDREW MAUDSLEY; Fiscal Year: 2009
    ....
  31. Real-Time MRI Motion Correction System
    Roland Bammer; Fiscal Year: 2007
    ..The optical system will track head position; correct for motion throughout image acquisition time; result in improved diagnostic image quality; and reduce, or even eliminate, the need for repeat studies due to patient head motion. ..
  32. DEVELOPMENT OF COMPLEX RETINAL FIELDS
    NORBERTO GRZYWACZ; Fiscal Year: 2001
    ..Incidence of orientation selectivity and receptive-field size will be measured for each of these conditions as a function of age, and the results compared to those of new computer simulations. ..
  33. The Organization of Semantic Memory
    Eiling Yee; Fiscal Year: 2007
    ..Together, these investigations will lead to a better understanding of how semantic information is organized, accessed and represented in normal subjects, and how semantic information degrades with various kinds of brain damage. ..
  34. Eyestrain in Radiologists
    Elizabeth Krupinski; Fiscal Year: 2007
    ..Only by developing a better understanding of the nature of observer error, may we discover effective approaches to reducing the errors. ..
  35. Volumetric MRSI Evaluation of Traumatic Brain Injury
    ANDREW MAUDSLEY; Fiscal Year: 2007
    ....
  36. Mechanisms of Acupuncture Analgesia
    Richard Harris; Fiscal Year: 2006
    ..There is a strong institutional commitment to see the applicant succeed in this task due to a tremendous need for well-trained clinical investigators in alternative and complementary medicine. ..
  37. NEURAL CORRELATES OF AGE-RELATED DIFFERENCES IN MEMORY
    Naftali Raz; Fiscal Year: 1993
    ..Are the deficits in procedural (skill) memory, frequently observed in older adults, related to age-dependent atrophy of the basal ganglia and the cerebellum?..
  38. Quantitative MRI analysis method for longitudinal assessment of knee OA
    JEFFREY W DURYEA; Fiscal Year: 2010
    ..The work will contribute to the public health indirectly by assisting others in developing and evaluating OA therapies. ..
  39. The Relationship of n-3 Fatty Acids with Pain and Synovium in knee OA
    Kristin Baker; Fiscal Year: 2007
    ..It is a major public health issue with substantial economic impact that will increase as the population ages. Individuals with the disease are eager for nonpharmacological treatments such as a nutrition intervention. ..
  40. MAGNETIC RESONANCE CORONARY ANGIOGRAPHY
    John Oshinski; Fiscal Year: 2001
    ....
  41. Characterization of a Novel 5-HT1A Receptor Agonist PET Ligand
    MATE MILAK; Fiscal Year: 2007
    ..Training research scientists in areas of translational research such as proposed here can accelerate the translation of new PET tracers to clinical research. ..
  42. Computerized Radiographic Outcomes for Rheumatoid Hands
    Jeffrey Duryea; Fiscal Year: 2004
    ..This work will play a major role towards alleviating the effects of this debilitating disease. ..
  43. Rapid Robust Pediatric MRI
    Shreyas S Vasanawala; Fiscal Year: 2010
    ....
  44. Hyperscan:Simultaneous fMRI across the internet
    Gregory Berns; Fiscal Year: 2002
    ..Linking together two 3 T scanners, one at Emory University and one at Princeton University, the biological substrates associated with human-human interaction will be compared to human-computer interaction. ..
  45. NEUROIMAGING OG NOVELTY DETECTION IN COCAINE DEPENDENCE
    Gregory Berns; Fiscal Year: 2003
    ..abstract_text> ..
  46. Neurobiology of Uncertainty
    Gregory Berns; Fiscal Year: 2009
    ..In this project, we will use modern brain imaging techniques to see how social messages from peers and authority figures change risky decisions and which parts of the brain are responsible. ..
  47. INTEGRATION OF BIFURCATION THEORY AND CONTINUOUS FMRI
    Gregory Berns; Fiscal Year: 2003
    ..The integration of bifurcation theory with continuous fMRI is anticipated to have a significant impact on the way in which fMRI experiments are conducted and will yield new techniques for the study of neuropsychiatric illness. ..
  48. Behavioral and Neural Correlates of Melodic Intonation Therapy
    Gottfried Schlaug; Fiscal Year: 2009
    ..Secondary outcome measures include correctly named items on standard picture naming tests, timed automatic speech, and linguistically-based measures of phrase and sentence analysis. Project Description Page 6 ..
  49. Facilitators of Motor Recovery Following Stroke
    Gottfried Schlaug; Fiscal Year: 2007
    ..abstract_text> ..
  50. Dectection of occult mediastinal lymph node mestastases
    Michael Wallace; Fiscal Year: 2007
    ..In the R33 component of the grant application these criteria will be prospectively evaluated and correlated with clinical outcome in a second, larger cohort of patients. ..
  51. Quantitative Cardiac PET/CT Imaging
    Adam Alessio; Fiscal Year: 2007
    ..This development will occur while contributing solutions to what are widely recognized as the most important challenges in cardiac PET/CT imaging. ..
  52. Vascular Dynamics in Functional MRI
    Thomas Liu; Fiscal Year: 2007
    ..1 Hz spectral index would allow investigators to more effectively determine which medications are likely to be of clinical value. ..