local anesthesia

Summary

Summary: A blocking of nerve conduction to a specific area by an injection of an anesthetic agent.

Top Publications

  1. ncbi Inguinal versus subinguinal varicocele vein ligation using magnifying loupe under local anesthesia: which technique is preferable in clinical practice?
    Paolo Gontero
    Clinica Urologica, Universita del Piemonte Orientale, Novara, Italy
    Urology 66:1075-9. 2005
  2. ncbi Optimizing local anesthesia during 10-core biopsy of the prostate
    M Schostak
    Department of Urology, University Hospital Benjamin Franklin, Freie Universitat, Berlin, Germany
    Urology 60:253-7. 2002
  3. ncbi Dexmedetomidine during local anesthesia
    Mahmoud I M Abdalla
    Faculty of Medicine, Ain Shams University, Cairo, Egypt
    J Anesth 20:54-6. 2006
  4. ncbi The use of local anesthesia with N-DO injector (Physion) for transurethral resection (TUR) of bladder tumors and bladder mapping: preliminary results and cost-effectiveness analysis
    Maurizio A Brausi
    Department of Urology, AUSL Modena, Modena, Italy
    Eur Urol 52:1407-11. 2007
  5. ncbi Effect of local anesthesia on trabeculectomy success
    Noa Geffen
    Ophthalmology Department, University Health Network
    J Glaucoma 17:658-61. 2008
  6. pmc Serious complications of local anaesthesia for cataract surgery: a 1 year national survey in the United Kingdom
    Tom Eke
    Norfolk and Norwich University Hospitals NHS Trust, Colney Lane, Norwich NR4 7UY, UK
    Br J Ophthalmol 91:470-5. 2007
  7. pmc Local anesthesia with ropivacaine for patients undergoing laparoscopic cholecystectomy
    Yu Yin Liu
    Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu Hsing Street, Kwei Shan, Taoyuan, Taiwan, China
    World J Gastroenterol 15:2376-80. 2009
  8. ncbi Effect of intraprostatic local anesthesia during transrectal ultrasound guided prostate biopsy: comparison of 3 methods in a randomized, double-blind, placebo controlled trial
    Ho Yun Lee
    Department of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Gyeonggi Do, Korea
    J Urol 178:469-72; discussion 472. 2007
  9. ncbi Needle and trocar injuries in diagnostic laparoscopy under local anesthesia: what is the true incidence of these complications?
    Rocco Orlando
    Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
    J Laparoendosc Adv Surg Tech A 13:181-4. 2003
  10. ncbi Intraprostatic local anesthesia with periprostatic nerve block for transrectal ultrasound guided prostate biopsy
    Liu Bingqian
    Department of Urology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China
    J Urol 182:479-83; discussion 483-4. 2009

Detail Information

Publications332 found, 100 shown here

  1. ncbi Inguinal versus subinguinal varicocele vein ligation using magnifying loupe under local anesthesia: which technique is preferable in clinical practice?
    Paolo Gontero
    Clinica Urologica, Universita del Piemonte Orientale, Novara, Italy
    Urology 66:1075-9. 2005
    ..To compare the intraoperative results of inguinal versus subinguinal varicocelectomy using magnifying loupe, in terms of vein ligation and arterial preservation, recurrence rate, and patient tolerability...
  2. ncbi Optimizing local anesthesia during 10-core biopsy of the prostate
    M Schostak
    Department of Urology, University Hospital Benjamin Franklin, Freie Universitat, Berlin, Germany
    Urology 60:253-7. 2002
    ..Reports thus far have shown a high variability in assessing the pain intensity of prostate biopsies and the effectiveness of anesthesia...
  3. ncbi Dexmedetomidine during local anesthesia
    Mahmoud I M Abdalla
    Faculty of Medicine, Ain Shams University, Cairo, Egypt
    J Anesth 20:54-6. 2006
    ..The study revealed that dexmedetomidine in the studied dose has a sedative effect, provides safe control of heart rate and blood pressure, and also decreases intraocular pressure during ophthalmic surgery under local anesthesia.
  4. ncbi The use of local anesthesia with N-DO injector (Physion) for transurethral resection (TUR) of bladder tumors and bladder mapping: preliminary results and cost-effectiveness analysis
    Maurizio A Brausi
    Department of Urology, AUSL Modena, Modena, Italy
    Eur Urol 52:1407-11. 2007
    We evaluated feasibility of TUR of Ta-T1 TCC of the bladder or bladder mapping under local anesthesia using a Physion endoinjector to see if correct tumor staging was possible, to check patient tolerability, and to analyze cost-..
  5. ncbi Effect of local anesthesia on trabeculectomy success
    Noa Geffen
    Ophthalmology Department, University Health Network
    J Glaucoma 17:658-61. 2008
    ..To compare the long-term results of trabeculectomy surgery with subconjunctival anesthesia versus topical lidocaine 2% jelly...
  6. pmc Serious complications of local anaesthesia for cataract surgery: a 1 year national survey in the United Kingdom
    Tom Eke
    Norfolk and Norwich University Hospitals NHS Trust, Colney Lane, Norwich NR4 7UY, UK
    Br J Ophthalmol 91:470-5. 2007
    ..The techniques of sub-Tenon's, topical and topical-intracameral local anaesthesia (LA) have become common in routine practice...
  7. pmc Local anesthesia with ropivacaine for patients undergoing laparoscopic cholecystectomy
    Yu Yin Liu
    Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu Hsing Street, Kwei Shan, Taoyuan, Taiwan, China
    World J Gastroenterol 15:2376-80. 2009
    ..To investigate the effect of pain relief after infusion of ropivacaine at port sites at the end of surgery...
  8. ncbi Effect of intraprostatic local anesthesia during transrectal ultrasound guided prostate biopsy: comparison of 3 methods in a randomized, double-blind, placebo controlled trial
    Ho Yun Lee
    Department of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Gyeonggi Do, Korea
    J Urol 178:469-72; discussion 472. 2007
    ..We evaluated the effect of intracapsular anesthesia and periprostatic nerve block during transrectal ultrasound guided prostate biopsy...
  9. ncbi Needle and trocar injuries in diagnostic laparoscopy under local anesthesia: what is the true incidence of these complications?
    Rocco Orlando
    Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
    J Laparoendosc Adv Surg Tech A 13:181-4. 2003
    ..Simply reporting complications as major or minor on the basis of the follow-up does not allow laparoscopists to understand their true incidence completely...
  10. ncbi Intraprostatic local anesthesia with periprostatic nerve block for transrectal ultrasound guided prostate biopsy
    Liu Bingqian
    Department of Urology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China
    J Urol 182:479-83; discussion 483-4. 2009
    ..We compared the pain control results of periprostatic nerve block alone vs periprostatic nerve block with intraprostatic anesthesia as local anesthesia for prostate biopsy.
  11. ncbi Anterior tension-free repair under local anesthesia of abdominal wall hernias in continuous ambulatory peritoneal dialysis patients
    E Gianetta
    Department of Surgery DICMI School of Medicine, University of Genova, Largo Rosanna Benzi 8, 1 16132 Genova, Italy
    Hernia 8:354-7. 2004
    ..experience of abdominal wall hernia repair performed with anterior tension-free mesh or plug technique under local anesthesia in end-stage renal failure patients submitted to continuous ambulatory peritoneal dialysis (CAPD) is ..
  12. ncbi A single-surgeon randomized trial comparing three composite meshes on chronic pain after Lichtenstein hernia repair in local anesthesia
    H Paajanen
    Department of General Surgery, The Central Hospital of Mikkeli, Porrassalmenkatu 35 37, 50100 Mikkeli, Finland
    Hernia 11:335-9. 2007
    ..Chronic pain may be a long-term problem related to operative trauma and mesh material in Lichtenstein hernioplasty...
  13. ncbi Impact of general versus local anesthesia on early postoperative cognitive dysfunction following carotid endarterectomy: GALA Study Subgroup Analysis
    Christian Friedrich Weber
    Department of Anesthesiology and Intensive Care Medicine, Goethe University, Frankfurt am Main, Germany
    World J Surg 33:1526-32. 2009
    ..Therefore, we performed a subgroup analysis of the multicenter GALA study...
  14. ncbi A meta-analysis of local anesthesia for transrectal ultrasound-guided biopsy of the prostate
    H Y Tiong
    Department of Urology, National University Hospital, Singapore, Singapore
    Prostate Cancer Prostatic Dis 10:127-36. 2007
    ....
  15. ncbi Percutaneous cryoablation of small pulmonary malignant tumors under computed tomographic guidance with local anesthesia for nonsurgical candidates
    Masafumi Kawamura
    Division of General Thoracic Surgery, School of Medicine, Keio University, Tokyo, Japan
    J Thorac Cardiovasc Surg 131:1007-13. 2006
    ..Cryoablation of pulmonary metastases might be a useful therapy for nonsurgical candidates...
  16. ncbi The quaternary lidocaine derivative, QX-314, produces long-lasting local anesthesia in animal models in vivo
    Tony K Y Lim
    Vancouver General Hospital, British Columbia, Canada
    Anesthesiology 107:305-11. 2007
    ..However, several reports document that extracellular QX-314 application affects action potentials. Hence, the authors tested the hypothesis that QX-314 could produce local anesthesia in animal models in vivo.
  17. ncbi Laparoscopic peritoneal dialysis catheter implantation using a Tenckhoff trocar under local anesthesia with nitrous oxide gas insufflation
    Amir Keshvari
    Department of Surgery, Imam Khomeini Hospital, Tehran, Iran
    Am J Surg 197:8-13. 2009
    ..The ability to perform laparoscopy with the patient under local anesthesia allows renal failure patients, who ordinarily might not be considered candidates for general anesthesia, an ..
  18. ncbi Sentinel node biopsy in melanoma of the trunk and the extremities in tumescent local anesthesia
    Klaus Eichhorn
    University Hospital Leipzig, Department of Dermatology, Dermatologic Surgery Unit, Leipzig, Germany
    Dermatol Surg 30:253-6. 2004
    The sentinel node biopsy (SNB) of axilla and groin is a common staging procedure and can be done in both general anesthesia and local anesthesia.
  19. ncbi Tumescent local anesthesia for a revascularization of a coronary subclavian steal syndrome
    Taketomo Mizukami
    Department of Cardiovascular Surgery, Onomichi General Hospital, Hiroshima, Japan
    Ann Thorac Cardiovasc Surg 13:352-4. 2007
    Tumescent local anesthesia (TLA), originally developed for liposuction, has found widespread application. We report a case of peripheral arterial bypass grafting under TLA...
  20. ncbi Endovascular repair of acute AAAs under local anesthesia with bifurcated endografts: a feasibility study
    Eric L G Verhoeven
    Department of Surgery, University Hospital of Groningen, The Netherlands
    J Endovasc Ther 9:729-35. 2002
    To evaluate endovascular repair of abdominal aortic aneurysms (AAA) under local anesthesia in the acute setting.
  21. ncbi Transcerebellar stereotactic biopsy for lesions of the brainstem and peduncles under local anesthesia
    Nader Sanai
    Department of Neurological Surgery, University of California San Francisco, San Francisco, California CA 94143 0112, USA
    Neurosurgery 63:460-6; discussion 466-8. 2008
    For certain brainstem lesions, a diagnostic biopsy is required for treatment planning. We reviewed the indications, safety, and diagnostic effectiveness of a transcerebellar stereotactic biopsy using local anesthesia and sedation.
  22. pmc Prolonged duration local anesthesia with minimal toxicity
    Hila Epstein-Barash
    Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Children s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 106:7125-30. 2009
    ..These results suggest that controlled release of STX and similar compounds can provide very prolonged nerve blocks with minimal systemic and local toxicity...
  23. ncbi Evaluation of continuous infusion of 0.5% bupivacaine by elastomeric pump for postoperative pain management after open inguinal hernia repair
    Karl A LeBlanc
    Surgical Specialty Group Inc, Baton Rouge, LA 70808, USA
    J Am Coll Surg 200:198-202. 2005
    ..Postoperative pain management and narcotic usage after inguinal hernia repair is an important concern for anesthesiologists and surgeons. Regional anesthesia incisional infiltration techniques may reduce the need for systemic medications...
  24. ncbi Periprostatic local anesthesia before ultrasound-guided prostate biopsy: an update of the miami experience
    A Vaidya
    Department of Urology, University of Miami School of Medicine, Miami, Fla 33101, USA
    Eur Urol 40:135-8. 2001
    ..Pain or discomfort associated with this procedure has been addressed recently by the use of periprostatic local anesthesia. We re-address this issue with an update of our experience and emphasize the crucial steps that contribute to ..
  25. ncbi Changes in Heart Rate Variability in patients under local anesthesia
    K Shafqat
    School of Engineering and Mathematical Sciences, City University, London, EC1V 0HB, UK
    Conf Proc IEEE Eng Med Biol Soc 2007:299-302. 2007
    ..Using this methodology electrocardiogram (ECG) signals from 14 patients undergoing local anesthesia (brachial plexus block) were analyzed with parametric Autoregressive (AR) method...
  26. ncbi Video-assisted thoracic surgery utilizing local anesthesia and sedation: 384 consecutive cases
    Mark R Katlic
    Division of Thoracic Surgery, Geisinger Health System, Wilkes Barre, Pennsylvania, USA
    Ann Thorac Surg 90:240-5. 2010
    ..There are risks to such anesthesia and some operations may not require general anesthesia or intubation. We elected to study the safety and efficacy of VATS utilizing local anesthesia, sedation, and spontaneous ventilation.
  27. ncbi Breast reduction using liposuction with tumescent local anesthesia and powered cannulas
    Louis Habbema
    Medisch Centrum t Gooi, Bussum, The Netherlands
    Dermatol Surg 35:41-50; discussion 50-2. 2009
    ..There is, therefore, a need for an effective technique that produces fewer of these undesirable features...
  28. ncbi Pain perception during transrectal ultrasound guided prostate needle biopsy: an objective analysis of local anesthesia use
    B N Stirling
    Department of Urology, Michigan State University College of Osteopathic Medicine, Metropolitan Hospital of Grand Rapids, Michigan, USA
    Prostate Cancer Prostatic Dis 5:209-11. 2002
    ..Patients were assigned to two groups: Group 1 received no local anesthesia and Group 2 received a periprostatic injection of 5 ml 1% lidocaine solution (2...
  29. ncbi Local anesthesia for the ophthalmic surgery. Select the best technique for your patient
    Mansoor Aqil
    Department of Anesthesiology, King Abdul Aziz University Hospital, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia
    Saudi Med J 31:605-14. 2010
    The majority of the ophthalmic surgical procedures are performed under local anesthesia as it provides excellent operating conditions for the surgery...
  30. ncbi Thyroidectomy using local anesthesia: a report of 1,025 cases over 16 years
    Kathryn Spanknebel
    Division of General Surgery, The New York Thyroid Center, Columbia University, College of Physicians and Surgeons, New York, USA
    J Am Coll Surg 201:375-85. 2005
    Thyroid surgery is performed using general anesthesia by the majority of surgeons in current practice. This study was conducted to analyze the utility and safety of local anesthesia for thyroid surgery.
  31. ncbi S-100B release during carotid endarterectomy under local anesthesia
    Marko Aleksic
    Division of Vascular Surgery, Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Ann Vasc Surg 21:571-5. 2007
    ..the study was to evaluate whether cross-clamping of the carotid artery for carotid endarterectomy (CEA) under local anesthesia is associated with the same S-100B release pattern as during general anesthesia, where an increase in S-100B ..
  32. ncbi A laparoscopic approach under local anesthesia for peritoneal dialysis access
    J H Crabtree
    Department of Surgery, Southern California Permanente Medical Group, Kaiser Permanente Bellflower Medical Center, 90706, USA
    Perit Dial Int 20:757-65. 2000
    ..Presented herein is a technical description of a time-proven laparoscopic approach to establishing successful long-term peritoneal dialysis access...
  33. ncbi Total mastectomy under local anesthesia: the tumescent technique
    Grant W Carlson
    Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Breast J 11:100-2. 2005
    ..Four patients (mean age 72 years, range 61-95 years) underwent a unilateral total mastectomy for cancer under local anesthesia using the tumescent technique of infiltrating dilute lidocaine with epinephrine (25 ml of 1% lidocaine [250 ..
  34. ncbi Hypertension: classification, pathophysiology, and management during outpatient sedation and local anesthesia
    Stephen Wilford Holm
    Oral and Maxillofacial Surgery, Carle Foundation Hospital, Urbana, IL, USA
    J Oral Maxillofac Surg 64:111-21. 2006
  35. ncbi Minimally invasive orbital decompression: local anesthesia and hand-carved bone
    Guy J Ben Simon
    Jules Stein Eye Institute and Department of Ophthalmology, The David Geffen School of Medicine, University of California, Los Angeles 90095 7006, USA
    Arch Ophthalmol 123:1671-5. 2005
    ....
  36. ncbi Four-step local anesthesia and sedation for thoracoscopic diagnosis and management of pleural diseases
    Marcello Migliore
    Section of General Thoracic Surgery, Department of Surgery, University of Catania, Catania, Italy
    Chest 121:2032-5. 2002
    Most thoracic surgeons perform thoracoscopy under general anesthesia using a double-lumen endotracheal tube. We describe our own technique for performing thoracoscopy under local anesthesia and sedation.
  37. ncbi Use of a new local anesthesia--intracorpus spongiosum anesthesia--in procedures on anterior urethra
    Gang Ye
    Department of Urology, Xinqiao Hospital, The Third Military Medical University, Chongqing, China
    Int J Urol 12:365-8. 2005
    ..The aim of the present study was to determine the efficacy of intracorpus spongiosum anesthesia during procedures on anterior urethra in the outpatient clinic...
  38. ncbi Sensory innervation of mandibular teeth by the nerve to the mylohyoid: implications in local anesthesia
    Pamela Stein
    Department of Anatomy and Neurobiology, University of Kentucky College of Medicine, Chandler Medical Center, Lexington, KY 40536 0298, USA
    Clin Anat 20:591-5. 2007
    ..This may prevent profound local anesthesia of the mandibular teeth and may account, at least in part, for the high failure rate of the inferior alveolar ..
  39. ncbi Combined analgesia and local anesthesia to minimize pain during circumcision
    A Taddio
    Department of Pharmacy, The Hospital for Sick Children, Toronto, Ontario, Canada
    Arch Pediatr Adolesc Med 154:620-3. 2000
    ..Pain of circumcision is only partially relieved by single modalities, such as penile nerve block, lidocaine-prilocaine cream, and sucrose pacifiers...
  40. ncbi Prostate innervation and local anesthesia in prostate procedures
    Alexandre Oliveira Rodrigues
    Department of Urology, Faculty of Medicine of the ABC, Brazil
    Rev Hosp Clin Fac Med Sao Paulo 57:287-92. 2002
    ..the human prostate is very abundant, and knowledge of the anatomy contributes to successful administration of local anesthesia. However, the exact anatomy of extrinsic neuronal cell bodies of the autonomic and sensory innervation of the ..
  41. ncbi The advancement of pure local anesthesia for penile surgeries: can an outpatient basis be sustainable?
    Geng Long Hsu
    Microsurgical Potency Reconstruction and Research Center, Taiwan Adventist Hospital, 424, Ba De Road, Sec 2, Taipei, Taiwan
    J Androl 28:200-5. 2007
    ..We report on several methods of topical blocks for local anesthesia in patients with indications for penile surgeries...
  42. ncbi Preinsertion local anesthesia at the trocar site improves perioperative pain and decreases costs of laparoscopic cholecystectomy
    N W Hasaniya
    Department of Surgery, Lee County Community Hospital, Medical Arts Building Suite 2, West Alternative Highway 58, Pennington Gap, VA 24277
    Surg Endosc 15:962-4. 2001
    b>Local anesthesia at the trocar site in laparoscopic cholecystectomy is expected to decrease postoperative pain and hence expedite recovery...
  43. ncbi 2-year followup pressure flow studies of prostate photoselective vaporization using local anesthesia with sedation
    John Martin Pedersen
    Department of Surgery, St Olav s University Hospital, Norwegian University of Science and Technology, Trondheim, Norway
    J Urol 181:1794-9. 2009
    We report 2-year pressure flow studies and other clinical outcomes of photoselective prostate vaporization with the patient under general or spinal anesthesia vs local anesthesia with sedation.
  44. ncbi Exogenous and endogenous plasma levels of epinephrine during dental treatment under local anesthesia
    M Lipp
    Klinik fur Anasthesiologie, Universitat Mainz, Germany
    Reg Anesth 18:6-12. 1993
    To determine serum levels of catecholamines after local anesthesia for dental treatment, we used tritium-labeled epinephrine as a vasoconstrictor for dental local anesthesia.
  45. ncbi Local anesthesia reduces pain associated with transrectal prostatic biopsy. A prospective randomized study
    Alberto Trucchi
    Urology Unit, Ospedale Sant Andrea, II Faculty of Medicine, La Sapienza, University of Rome, Rome, Italy
    Urol Int 74:209-13. 2005
    ..To test the hypothesis that periprostatic block could completely relief prostatic biopsy-associated pain...
  46. ncbi Recent developments in local anesthesia and oral sedation
    John A Yagiela
    Division of Diagnostic and Surgical Sciences, University of California, Los Angeles School of Dentistry, Los Angeles, California, USA
    Compend Contin Educ Dent 25:697-706; quiz 708. 2004
    ..The recent administration of triazolam in multiple doses has extended the availability of anxiety control to many dental patients, but unknowns about the safety of the technique as practiced by some dentists remains a concern...
  47. ncbi Minimal invasive lymphaticovenular anastomosis under local anesthesia for leg lymphedema: is it effective for stage III and IV?
    Isao Koshima
    Department of Plastic and Reconstructive Surgery, Graduate School of Medicine and Dentistry, Okayama University, Okayama, Japan
    Ann Plast Surg 53:261-6. 2004
    This is the first report on the effectiveness of minimal invasive lymphaticovenular anastomosis under local anesthesia for leg lymphedema...
  48. ncbi Local anesthesia strategies for the patient with a "hot" tooth
    John M Nusstein
    Division of Endodontics, The Ohio State University College of Dentistry, 305 West 12th Avenue, Room 3058, Columbus, OH 43210, USA
    Dent Clin North Am 54:237-47. 2010
    Attaining local anesthesia for the treatment of teeth diagnosed with irreversible pulpitis ("hot" tooth) can be a challenge...
  49. ncbi Can the Iowa Satisfaction with Anesthesia Scale be used to measure patient satisfaction with cataract care under topical local anesthesia and monitored sedation at a community hospital?
    Donald Fung
    North Bay General Hospital, 750 Scollard, North Bay, Ontario, Canada
    Anesth Analg 100:1637-43. 2005
    ..the Iowa Satisfaction with Anesthesia Scale (ISAS) to measure satisfaction with cataract care under topical local anesthesia and monitored sedation given by an anesthesiologist at a community hospital...
  50. ncbi What determines patient satisfaction with cataract care under topical local anesthesia and monitored sedation in a community hospital setting?
    Donald Fung
    North Bay General Hospital, 750 Scollard, North Bay, Ontario, Canada
    Anesth Analg 100:1644-50. 2005
    ..We used the ISAS to discover determinants of patient satisfaction with cataract care under topical local anesthesia and monitored sedation in a small community hospital...
  51. ncbi Extracorporeal shock wave therapy without local anesthesia for chronic lateral epicondylitis
    Frank A Pettrone
    Commonwealth Orthopaedics, 1635 North George Mason Drive, Suite 310, Arlington, VA 22205, USA
    J Bone Joint Surg Am 87:1297-304. 2005
    ..The purpose of this study was to evaluate the use of extracorporeal shock wave therapy without local anesthesia to treat chronic lateral epicondylitis.
  52. ncbi Multiple Z-plasty in pilonidal sinus--a new technique under local anesthesia
    Pradeep Purushottam Sharma
    Department of Surgery, Bharati Vidyapeeth Medical College and Hospital, Jehangir Hospital, Sassoon Road, Pune, Maharashtra, 411001, India
    World J Surg 30:2261-5. 2006
    ..Many procedures have been tried, ranging from nonsurgical to surgical methods (both conservative and radical ones). It is well known that recurrences are low when the scar is away from the midline...
  53. ncbi Transurethral cystolithotripsy with holmium laser under local anesthesia in selected patients
    Cengiz Kara
    Department of Urology, Ministry of Health, Kecioren Training and Research Hospital, Kecioren, Ankara, Turkey
    Urology 74:1000-3. 2009
    To evaluate the feasibility and effectiveness of transurethral holmium:yttrium-aluminum-garnet (YAG) laser cystolithotripsy under local anesthesia in selected patients.
  54. ncbi Safety of liposuction using exclusively tumescent local anesthesia in 3,240 consecutive cases
    Louis Habbema
    Department of Dermatology, Medisch Centrum t Gooi, Bussum, The Netherlands
    Dermatol Surg 35:1728-35. 2009
    Many surgeons consider liposuction using tumescent local anesthesia (TLA) to be a safe technique, but when TLA has been combined with other techniques, such as general anesthesia or intravenous medication, or when the guidelines ..
  55. ncbi Local anesthesia using buffered 0.5% lidocaine with 1:200,000 epinephrine for tumors of the digits treated with Mohs micrographic surgery
    Bahar Firoz
    DermSurgery Associates, Houston, Texas 77030, USA
    J Am Acad Dermatol 61:639-43. 2009
    Several specialties and textbooks continue to advocate that local anesthesia using epinephrine should not be used during surgery involving the digits.
  56. ncbi Combined periprostatic and intraprostatic local anesthesia for prostate biopsy: a double-blind, placebo controlled, randomized trial
    Kamil Cam
    Department of Urology, Duzce University Medical School, Duzce, Turkey
    J Urol 180:141-4; discussion 144-5. 2008
    ..We prospectively evaluated the contribution of intraprostatic anesthesia for transrectal prostate biopsies even when the sampling number was doubled to 12 cores...
  57. ncbi Delayed onset of altered sensation following dental implant placement and mental block local anesthesia: a case report
    Dennis Flanagan
    Implant Dent 11:324-30. 2002
    ..The altered sensation was probably caused by the mental block anesthetic technique. The partial anesthetic area in this case was probably a result of crossover innervation from the contralateral mental nerve...
  58. ncbi Neuromonitoring of the external branch of the superior laryngeal nerve during minimally invasive thyroid surgery under local anesthesia: a prospective study of 10 patients
    William B Inabnet
    Department of Surgery, Division of Gastrointestinal and Endocrine Surgery, Columbia University, New York, New York 10032, USA
    Laryngoscope 119:597-601. 2009
    ..This study aims to assess feasibility and efficacy of a novel technique of neuromonitoring of the EBSLN under local anesthesia during minimally invasive thyroidectomy. STUDY DESIGN;
  59. ncbi Ureteroscopic removal of mildly migrated stents using local anesthesia only
    Kostantinos E Livadas
    Second Department of Urology, Athens Medical School, Sismanoglio Hospital, Athens, Greece
    J Urol 178:1998-2001. 2007
    ..In the outpatient office setting we evaluated the feasibility and efficacy of ureteroscopic removal of upward migrated ureteral stents using local or no anesthesia...
  60. ncbi [Influence of local anesthesia and energy level on the clinical outcome of extracorporeal shock wave-treatment of chronic plantar fasciitis]
    G Labek
    Orthopädische Abteilung, Allgemeines Krankenhaus Linz, Osterreich
    Z Orthop Ihre Grenzgeb 143:240-6. 2005
    The efficacy of low energy extracorporeal shock wave treatment (ESWT) for chronic plantar fasciitis is discussed controversially. It is unclear whether the simultaneous application of local anesthesia (LA) interferes with clinical outcome.
  61. ncbi Complications and limitations related to periprostatic local anesthesia before TRUS-guided prostate biopsy
    Ahmet T Turgut
    Department of Radiology, Ankara Training and Research Hospital, Ankara 06590, Turkey
    J Clin Ultrasound 36:67-71. 2008
    ..To assess the frequency of complications specifically related to local anesthetic infiltration prior to transrectal ultrasound (TRUS)-guided prostate biopsy...
  62. ncbi Postoperative internal carotid artery restenosis after local anesthesia: presence of risk factors versus intraoperative shunt
    Narcis Hudorovic
    Department of Vascular Surgery, University Hospital Sestre Milosrdnice, Vinogradska 29, 10000 Zagreb, Croatia
    Interact Cardiovasc Thorac Surg 11:182-4. 2010
    ..At the same time local anesthesia reduced the shunt insertion rate...
  63. ncbi Comparison of different local anesthesia techniques during TRUS-guided biopsies: a prospective pilot study
    Sergey Kravchick
    Department of Urology, Barzilai Medical Center, Ashkelon, Israel
    Urology 65:109-13. 2005
    To introduce two forms of anesthesia and compare them with standard local anesthesia techniques.
  64. ncbi Efficacy of tumescent local anesthesia with variable lidocaine concentration in 3430 consecutive cases of liposuction
    Louis Habbema
    Medisch Centrum t Gooi, Bussum, and Erasmus MC Department of Dermatology, Rotterdam, The Netherlands
    J Am Acad Dermatol 62:988-94. 2010
    Lidocaine toxicity is a potential complication related to using tumescent local anesthesia (TLA) as the exclusive form of pain management in surgical procedures.
  65. ncbi [Temporary suppression of tremor by remifentanil in a patient with Parkinson's disease during cataract extraction under local anesthesia]
    W Böhmdorfer
    Abteilung für Anästhesie und Intensivmedizin, KA Rudolfstiftung Wien, Austria
    Anaesthesist 52:795-7. 2003
    ..A patient with Parkinson's disease refused both anti-Parkinson medication and general anaesthesia. Low dose remifentanil infusion suppressed her otherwise severe tremor, and the operation was performed uneventfully under local anaesthesia...
  66. ncbi Local anesthesia use for laparoscopic cholecystectomy
    Aydin Inan
    Department of General Surgery, Fatih University School of Medicine, Fatih Universitesi Hastanesi, Alparslan Turkes Caddesi No 57, Bestepe, Emek, 06510, Ankara, Turkey
    World J Surg 28:741-4. 2004
    This study aimed to investigate the effects and timing of local anesthesia during laparoscopic surgery in terms of postoperative pain, nausea, and the need for opioids and antiemetics...
  67. ncbi Effects of ring castration with local anesthesia and analgesia in Holstein calves at 3 months of age on welfare indicators
    S Marti
    Department of Ruminant Production, Institut de Recerca i Tecnologia Agroalimentaries IRTA, and Animal Nutrition, Management, and Welfare Research Group, Torre Marimon, 08140 Caldes de Montbui, Barcelona, Spain
    J Anim Sci 88:2789-96. 2010
    ..Castration was performed with local anesthesia (2% lidocaine, 3 mL in each testis and 2 mL in the scrotum) and analgesia (flunixin meglumine, ..
  68. ncbi Renal capsular block: a novel method for performing percutaneous nephrolithotomy under local anesthesia
    D Dalela
    Department of Urology, CSM Medical University, Upgraded King George s Medical College, Lucknow UP, India
    J Endourol 18:544-6. 2004
    ..We evolved a technique to block renal capsular sensations by infiltration of lignocaine (lidocaine) at the site of renal entry, permitting the procedure to be done with local anesthesia.
  69. ncbi Radio-guided minimally invasive parathyroidectomy under local anesthesia
    Assim Alfadda
    Department of Internal Medicine, King Saud University, Riyadh, Saudi Arabia
    West Afr J Med 25:134-7. 2006
    ..In an attempt to reduce operative time and decrease perioperative morbidity, we reported our experience with radio-guided minimally invasive parathyroidectomy (RMIP) under local anesthesia.
  70. ncbi Effect of ketoprofen, lidocaine local anesthesia, and combined xylazine and lidocaine caudal epidural anesthesia during castration of beef cattle on stress responses, immunity, growth, and behavior
    S T L Ting
    Teagasc, Grange Research Centre, Dunsany, Co Meath, Ireland
    J Anim Sci 81:1281-93. 2003
    To determine the effects of burdizzo castration alone or in combination with ketoprofen (K), local anesthesia (LA), or caudal epidural anesthesia (EPI) on plasma cortisol, acute-phase proteins, interferon-gamma production, growth, and ..
  71. ncbi Local anesthesia during 10 core biopsy of the prostate: comparison of 2 methods
    Kazuaki Mutaguchi
    Division of Frontier Medical Science, Department of Urology, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    J Urol 173:742-5. 2005
    We investigated the effectiveness of a new method, intraprostatic administration of local anesthesia vs traditional periprostatic injection for decreasing the discomfort caused by transrectal ultrasound guided, 10 core biopsy of the ..
  72. ncbi Outpatient varicocelectomy performed under local anesthesia
    Geng Long Hsu
    Microsurgical Potency Reconstruction and Research Center, Taiwan Adventist Hospital, 424, Pa Te Road, Sec 2, Taipei 105, Taiwan, China
    Asian J Androl 7:439-44. 2005
    To report a series of varicocelectomy performed under pure local anesthesia.
  73. ncbi Comparison of oral and vaginal misoprostol for cervical ripening before manual vacuum aspiration of first trimester pregnancy under local anesthesia: a randomized placebo-controlled study
    Leyla Cakir
    Family Planning Clinic, SSK Social Security Organization Maternity and Women s Health Training Hospital, 06010 Ankara, Turkey
    Contraception 71:337-42. 2005
    ..mug vaginal misoprostol administration for cervical priming 3 h prior to manual vacuum aspiration (MVA) under local anesthesia for voluntary termination of pregnancy before 10 weeks of gestation in comparison with placebo oral or ..
  74. ncbi Local anesthesia for transurethral manipulations: is a transrectal periprostatic nerve block effective?
    Michael Muntener
    Department of Urology, University Hospital, Zurich, Switzerland
    World J Urol 23:349-52. 2005
    ..The mean pain score was 3.4 in group 1 and 3.9 in group 2. This difference was not statistically significant. We conclude that nerve block does not seem to reduce the pain associated with transurethral manipulations...
  75. ncbi Is periprostatic local anesthesia for transrectal ultrasound guided prostate biopsy associated with increased infectious or hemorrhagic complications? A prospective randomized trial
    Can Obek
    Department of Urology, University of Istanbul Cerrahpasa School of Medicine, Istanbul, Turkey
    J Urol 168:558-61. 2002
    Periprostatic local anesthesia for prostate biopsy requires 2 or more extra needle punctures and injection of the local anesthetic through the highly colonized rectum...
  76. ncbi Advanced techniques and armamentarium for dental local anesthesia
    Taylor M Clark
    Dental Anesthesiology Residency Program, School of Dentistry, University of California, Los Angeles, Los Angeles, CA 90095 1668, USA
    Dent Clin North Am 54:757-68. 2010
    ..Supplementary IO anesthesia is particularly suited for providing effective pain control of teeth diagnosed with irreversible pulpitis...
  77. ncbi Genioglossus advancement and hyoid myotomy under local anesthesia
    Chairat Neruntarat
    Department of Otolaryngology, Srinakharinwirot University, Vajira Hospital, Bangkok, Thailand
    Otolaryngol Head Neck Surg 129:85-91. 2003
    ..The purpose of this study was to assess the safety and efficacy of GAHM for the treatment of OSAS with the patient under local anesthesia.
  78. ncbi Tetrodotoxin for prolonged local anesthesia with minimal myotoxicity
    Robert F Padera
    Department of Pathology, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Muscle Nerve 34:747-53. 2006
    ..Epinephrine did not worsen TTX's relatively minimal cytotoxicity. Tetrodotoxin may thus be useful in producing prolonged nerve block with minimal myotoxicity and perhaps neurotoxicity...
  79. ncbi Better short-term outcomes with the U-method compared with the Hammock technique for the implantation of the TVT-SECUR under local anesthesia
    Louis Olivier Gagnon
    Service d Urologie, Centre Hospitalier Universitaire de Sherbrooke CHUS, Universite de Sherbrooke, Quebec, Canada
    Urology 75:1060-4. 2010
    To observe the satisfaction of local anesthesia during the implantation of the tension-free vaginal tape (TVT)-SECUR (Gynecare, Ethicon, Somerville, NJ) for the treatment of stress urinary incontinence, using questionnaires completed by ..
  80. ncbi Corneal endothelial safety of intracameral preservative-free 1% xylocaine
    Alpesh R Shah
    Iladevi Cataract and IOL Research Centre, Ahmedabad, India
    Indian J Ophthalmol 52:133-8. 2004
    ..To evaluate the effect of intracameral preservative-free 1% xylocaine on the corneal endothelium as an adjuvant to topical anaesthesia during phacoemulsification and Acrysof foldable IOL implantation...
  81. ncbi Simple harmonic scalpel hemorrhoidectomy utilizing local anesthesia combined with intravenous sedation: a safe and rapid alternative to conventional hemorrhoidectomy
    Liam A Haveran
    Section of Colon and Rectal Surgery, University of Massachusetts Medical Center, Worcester, MA 01655, USA
    Int J Colorectal Dis 22:801-6. 2007
    ..There was a trend toward performing hemorrhoid surgery as an ambulatory procedure using local anesthesia supplemented with intravenous sedation...
  82. ncbi One-thousand consecutive inguinal hernia repairs under unmonitored local anesthesia
    T Callesen
    Department of Surgical Gastroenterology, H S Hvidovre University Hospital, Hvidovre, Denmark
    Anesth Analg 93:1373-6, table of contents. 2001
    To evaluate the feasibility and safety of unmonitored local anesthesia (ULA) for elective open inguinal hernia repair, we made a prospective, consecutive data collection from 1000 operations on primary and recurrent hernias...
  83. pmc Lignocaine toxicity; a complication of local anaesthesia administered in the community
    M J Donald
    Department of Emergency Medicine, Manly Hospital, Sydney, Australia
    Emerg Med J 21:249-50. 2004
    ..Emergency practitioners should maintain a high level of vigilance for the symptoms of toxicity after local anaesthetic administration. Particular care should be taken when calculating the maximum safe dose for young children...
  84. ncbi Local anesthesia for functional endoscopic sinus surgery employing small volumes of epinephrine-containing solutions of lidocaine produces profound hypotension
    J J Yang
    Department of Anesthesiology, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    Acta Anaesthesiol Scand 49:1471-6. 2005
    ....
  85. ncbi A comparison of patient pain during cataract surgery with topical anesthesia in Prechop Manual Phacofragmentation versus phacoemulsification
    Pipat Kongsap
    Department of Ophthalmology, Prapokklao Hospital, Chantaburi, Thailand
    J Med Assoc Thai 89:959-66. 2006
    ..To compare the pain level and complications during cataract surgery with topical anesthesia in Prechop MPF versus phacoemulsification...
  86. ncbi Randomized prospective study of periprostatic local anesthesia during transrectal ultrasound-guided prostate biopsy
    Issac Kaver
    Department of Urology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Urology 59:405-8. 2002
    ..To prospectively evaluate the efficacy of apical and lateral periprostatic lidocaine injection as anesthesia during transrectal ultrasound-guided prostate biopsy...
  87. ncbi An ambulatory surgical procedure under local anesthesia for treatment of female urinary incontinence
    U Ulmsten
    Department of Obstetrics and Gynecology, Akademiska sjukhuset, Uppsala University, Sweden
    Int Urogynecol J Pelvic Floor Dysfunct 7:81-5; discussion 85-6. 1996
    ..modified intravaginal slingplasty for the surgical treatment of female stress incontinence, carried out under local anesthesia as a day procedure...
  88. ncbi Carotid endarterectomy under local anesthesia in elderly: is it worthwhile?
    B Amato
    Department of General and Geriatric Surgery, University of Naples Federico II, Naples, Italy
    Acta Biomed 76:64-8. 2005
    ..5%). Surgery for carotid artery occlusive disease under local anaesthesia can be safely performed in selected patients of more than 75 yr of age...
  89. ncbi Local anesthesia for ultrasound guided prostate biopsy: a prospective randomized trial comparing 2 methods
    A S Alavi
    Department of Urology, University of Miami School of Medicine, Miami, Florida, USA
    J Urol 166:1343-5. 2001
    ..CONCLUSIONS: Men should have the opportunity to receive local anesthesia before ultrasound guided prostate biopsy with the goal of decreasing the discomfort associated with this ..
  90. ncbi A randomized, controlled trial of the reciprocating procedure device for local anesthesia
    Sharon E Nunez
    Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA
    J Emerg Med 35:119-25. 2008
    ..new reciprocating procedure device (RPD) is superior to the conventional syringe for the administration of local anesthesia. There were 209 local lidocaine anesthesia procedures randomized between the RDP and the conventional syringe...
  91. ncbi Isobolographic analysis of epinephrine with bupivacaine, dextromethorphan, 3-methoxymorphinan, or dextrorphan on infiltrative anesthesia in rats: dose-response studies
    Yu Wen Chen
    Department of Physical Therapy, China Medical University, Taichung, Taiwan
    Reg Anesth Pain Med 33:115-21. 2008
    ..Bupivacaine, a common and long-acting local anesthetic, was used as control...
  92. ncbi Minimally invasive parathyroidectomy using local anesthesia with intravenous sedation and targeted approaches
    Maisie L Shindo
    SUNY at Stony Brook, Stony Brook, NY 11794, USA
    Otolaryngol Head Neck Surg 138:381-7. 2008
    Minimally invasive parathyroidectomy (MIP) is generally performed under general anesthesia. This study evaluates the efficacy and safety of MIP performed under intravenous sedation with local anesthesia.
  93. ncbi Comparison of local anesthesia techniques during transrectal ultrasound-guided biopsies
    Brian N Stirling
    Department of Urology, Michigan State University College of Osteopathic Medicine Urologic Consortium, Metropolitan Hospital of Grand Rapids, Grand Rapids, Michigan 49546, USA
    Urology 60:89-92. 2002
    ..To compare the effectiveness of periprostatic nerve blockade versus intrarectal lidocaine during transrectal ultrasound-guided biopsies...
  94. ncbi Micro-orifice metabolic/bariatric surgery under IV sedation/local anesthesia: porcine feasibility study
    Henry Buchwald
    Department of Surgery, University of Minnesota, MMC 290, Minneapolis, MN 55455, USA
    Obes Surg 20:500-5. 2010
    ..approach has certain disadvantages that can be avoided by a technique for abdominal access via a micro-orifice incision under intravenous (IV) sedation/local anesthesia, without general anesthesia, insufflation, and intubation.
  95. pmc Preemptive analgesia and local anesthesia as a supplement to general anesthesia: a review
    Eliezer Kaufman
    Department of Oral Medicine, The Hebrew University Hadassah School of Dental Medicine, Jerusalem, Israel
    Anesth Prog 52:29-38. 2005
    General anesthesia (GA) and local anesthesia (LA) evolved on separate tracks. Procedures that could not be performed under LA were typically conducted under GA...
  96. ncbi Current trends in local anesthesia in cosmetic plastic surgery of the head and neck: results of a German national survey and observations on the use of ropivacaine
    Tobias Koeppe
    Department of Plastic and Reconstructive Surgery, Marienhospital Stuttgart, Stuttgart, Germany
    Plast Reconstr Surg 115:1723-30. 2005
    ..at the national level the current practice in the use of local anesthetics in cosmetic head and neck surgery and to compare the results with the novel local anesthesia technique used in the authors' department over the past 2 years.
  97. ncbi Local anesthesia before transrectal ultrasound guided prostate biopsy: comparison of 2 methods in a prospective, randomized clinical trial
    Stéphane Mallick
    Department of Urology, University Hospital, Pointe a Pitre, Guadeloupe, French West Indies, France
    J Urol 171:730-3. 2004
    ..We compared the analgesic efficacy of the rectal administration of lidocaine gel and lidocaine periprostatic infiltration prior to transrectal ultrasound guided prostatic biopsies...
  98. pdf Cortical stimulation of language fields under local anesthesia: optimizing removal of brain lesions adjacent to speech areas
    Robson Luis Oliveira de Amorim
    Division of Functional Neurosurgery, Department of Neurology, Clinics Hospital, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
    Arq Neuropsiquiatr 66:534-8. 2008
    ..We have assessed the safety and effectiveness of craniotomy under local anesthesia and monitored conscious sedation for the resection of lesions involving eloquent language cortex.
  99. ncbi A simplified endoscopic third ventriculostomy under local anesthesia
    P L Longatti
    Department of Neurosurgery, Regional Hospital, Treviso, Italy
    Minim Invasive Neurosurg 47:90-2. 2004
    ..From September 1994 to December 2001, 24 neuroendoscopic procedures were performed under local anesthesia. Local infiltration was administered using a bupivacaine and lidocaine mixture...
  100. ncbi Arthroscopic release of the piriformis muscle under local anesthesia for piriformis syndrome
    Akira Dezawa
    Department of Orthopaedic Surgery, School of Medicine, University of Teikyo, Mizonokuchi Hospital, Kawasaki, Japan
    Arthroscopy 19:554-7. 2003
    ..This technique is useful for reducing postoperative pain and allows early return to activity...
  101. ncbi Local anesthesia with 20-mL prilocaine infiltration: the ultimate point for analgesia during shockwave lithotripsy?
    Erdal Yilmaz
    Faculty of Medicine, Department of Urology, University of Kirikkale, Kirikkale, Turkey
    J Endourol 22:883-7. 2008
    ..The effectiveness of 10 mL and 20 mL local prilocaine infiltration for analgesic purposes during shockwave lithotripsy (SWL) was compared, and the differences in pain intensity and need for additional analgesics were defined...

Research Grants62

  1. NEW DERMAL ANESTHETICS
    VINCENT CIOFALO; Fiscal Year: 2003
    ..The new compounds offer faster onset of anesthetic activity, deeper local anesthesia, and longer duration of anesthesia than EMLA...
  2. Mentored Patient-Oriented Research Career Development Aw
    Kelly Young; Fiscal Year: 2004
    ..African-American, and Mexican-American, undergoing painful medical procedures typically done with no or local anesthesia only (e.g...
  3. TRANSPLANTATION OF HUMAN BONE MARROW STROMAL CELLS
    Itzhak Fischer; Fiscal Year: 2004
    ..Human MSCs are easy to obtain from a patient under local anesthesia, provide a renewal population and can be used for autologous grafting...
  4. Minimally Invasive Surgical Therapies Treatment Consort*
    Claus Roehrborn; Fiscal Year: 2005
    ..the relative efficacy and safety, as well as tolerability of these procedures in an outpatient setting under local anesthesia, and importantly, durability of the initial results over intermediate follow-up periods is lacking...
  5. Sodium Channel Expression in Human Teeth
    Michael Henry; Fiscal Year: 2009
    ..from this study will further our knowledge regarding both basic pain mechanisms and the increased occurrence of local anesthesia failures in diseased teeth that can be a major deterrent for utilization of dental care.
  6. Pathogenesis of Postoperative Cognitive Dysfunction
    Zhongcong Xie; Fiscal Year: 2013
    ..can also lead to POCD in humans, our Preliminary studies in mice have shown that open abdominal surgery under local anesthesia induced neuroinflammation, A[unreadable] accumulation, and neurobehavioral deficits...
  7. Treating cutaneous leishmaniasis by radio-frequency induced heat (RFH) therapy
    Abhay R Satoskar; Fiscal Year: 2012
    ..This treatment delivers controlled and localized radiofrequencies into lesions for 30-60 seconds under local anesthesia. Several short-term follow-up (4-5 months) studies and one long-term follow-up (12 months) study involving US ..
  8. Local anesthetic receptor in peripheral Na+ channels
    GING K WANG; Fiscal Year: 2013
    ..LAs) block voltage-gated Na+ channels and impede both motor and sensory functions reversibly during local anesthesia. The receptor for LAs in peripheral Na+ channels is therefore an important target for therapeutics...
  9. Enhanced Provision of Male Circumcision for HIV Prevention, Rakai, Uganda
    Ronald H Gray; Fiscal Year: 2013
    ..We will first train personnel in EIMC using the Mogen clamp under local anesthesia, and then enroll 500 infants aged <2 months per arm...
  10. Pediatric Percutaneous Cochlear Implantation Clinical Validation &Implementation
    Robert F Labadie; Fiscal Year: 2012
    ..the following six steps: (i) placing three bone-implanted fiducial markers/anchors surrounding the ear under local anesthesia in an out-patient setting, (ii) obtaining a clinically applicable CT scan, (iii) using the CT scan to plan a ..
  11. Tear-Resistant and Elastic Tissue Adhesive for Craniofacial Applications
    SILVIA D LUEBBEN; Fiscal Year: 2012
    ..The use of tissue adhesives in place of sutures also eliminates the need for local anesthesia and follow-up visits to remove the stiches when non-biodegradable sutures are used...
  12. Adult Stem Cell Minimally Invasive Bone Marrow Harvester
    DANIEL LEWIS KRAFT; Fiscal Year: 2012
    ..designed to obtain significant volumes of rich bone marrow in a minimally invasive manner (one stick under local anesthesia), by using a powered flexible shaft specifically designed to move through the confines of the pelvis...
  13. MICROINVASIVE TREATMENT OF SLEEP APNEA WITH THE LINGUAFLEX TISSUE RETRACTOR II
    Ira Sanders; Fiscal Year: 2010
    ..The therapy involves the insertion of a thin, elastic implant into the side of the tongue, under local anesthesia. The device will be tested in animals and human cadaver specimen...
  14. PROLONGED DURATION LOCAL ANESTHESIA
    Daniel S Kohane; Fiscal Year: 2013
    ..The purpose of this application is to develop means of treating such localized pain with a single injection that would last for days to weeks without patients having to take pain medications that would cloud their minds. ..
  15. Auditory Thalamic Implant
    STEVEN WAN CHEUNG; Fiscal Year: 2012
    ..is device implantation of the ventral medial geniculate body via supratentorial burr hole craniotomy under local anesthesia. Adaptation of established deep brain stimulation and computer assisted surgical navigation technologies to ..
  16. TRPV1 mediation of local vasoconstrictor reflexes in spinal cord injured humans
    Dean L Kellogg; Fiscal Year: 2013
    ..Aims 2 and 3 will be tested in the same groups by comparing the effects of local anesthesia and TRPV1 receptor antagonism on myogenic responses and the VAR during limb dependency and limb cuff ..
  17. Evaluation of Sodium Channel Inhibitors as Therapeutics for Chronic Muscle Disord
    JOHN VINCENT MULCAHY; Fiscal Year: 2013
    ..analogues showing an improved margin of safety and extended duration of action in in vivo models measuring local anesthesia and inhibition of muscle contraction...
  18. Actions of Local Anesthetics on NMDA Receptors
    Meaghan Paganelli; Fiscal Year: 2013
    ..mechanism by which lidocaine and bupivacaine, two widely used local anesthetics, reduce NMDA receptor activity and will provide needed information about how local anesthesia can prevent or reduce the development of central sensitization.
  19. Ocular blood flow and intraocular pressure homeostasis
    Jeffrey W Kiel; Fiscal Year: 2013
    ..Given that the episcleral circulation is innervated and that most published EVP measurements were made under local anesthesia, that assumption is probably wrong...
  20. AROMATIC AMINE LOCAL ANESTHETICS AND MEMBRANES
    Issaku Ueda; Fiscal Year: 1990
    b>Local anesthesia is generally considered to involve specific binding to receptors, most probably to the sodium channel whose gate is opened...
  21. Peripheral and Central Mechanism of Pain in Patients with Fibromyalgia
    ROLAND M STAUD; Fiscal Year: 2010
    ..Either way, we will provide evidence that will characterize the role of local anesthesia, placebo analgesia, or both...
  22. NATURAL HISTORY AND TREATMENT OUTCOME IN BRAIN AVM
    JP MOHR; Fiscal Year: 2005
    ..on-the-table assessments of cerebral function derived from Behavior Science principles and undertaken with local anesthesia challenges using agents with differential effects on brain white and gray matter...
  23. PROLONGED DURATION LOCAL ANESTHESIA
    DANIEL KOHANE; Fiscal Year: 2004
    ..Finally, we will study the effectiveness of prolonged duration local anesthesia in preventing or mitigating the development of pain-related behaviors and the rise in GAP-43 expression ..
  24. BRAIN STEM MECHANISMS OF DEEP CRANIOFACIAL PAIN
    James Hu; Fiscal Year: 1993
    ..the peripherally evoked responses to deep as well as cutaneous stimuli of caudalis nociceptive neurons; local anesthesia or lesioning of RVM can diminish the depressive effects of PAG stimulation...
  25. COCAINE USE: ACUTE AND CHRONIC CARDIOVASCULAR EFFECTS
    ROBERT WILKERSON; Fiscal Year: 1991
    ..e. inhibition of neuronal catecholamine uptake and local anesthesia) are well established, the mechanism(s) of its cardiovascular actions are not understood...
  26. BIOMECHANICS OF THE ROTATOR CUFF
    Kai Nan An; Fiscal Year: 1999
    ..measuring the strength of patients with cuff pathology and associated pain, before and after injection with local anesthesia. Postulates based on the effects of tear size and number of tendons involved will be tested...
  27. NOVEL DELIVERY SYSTEM FOR TOPICAL ANESTHESIA
    Bakul Bhatt; Fiscal Year: 2000
    ..PROPOSED COMMERCIAL APPLICATIONS: The number of procedures requiring local anesthesia and the extent to which local anesthetics are being used is steadily increasing...
  28. STUDY OF OCULOMOTOR CONTROL SYSTEM
    David Robinson; Fiscal Year: 1993
    ..We will investigate this in the alert monkey by microstimulation and micro injections of a local anesthesia in this region to provide evidence that may suggest how the neural integrator works...
  29. Image-Guided Otologic Surgery
    Robert Labadie; Fiscal Year: 2004
    ..gold standard for fiducial markers is a rigid frame which is screwed directly into the patient's skull under local anesthesia. Registration involves identifying the fiducial markers on both the patient and the X-ray images and then ..
  30. Indirect Lymphosonography for Sentinel Node Localization
    Robert Mattrey; Fiscal Year: 2005
    ..If the node is accessible, resection could potentially be done under local anesthesia or by use of a percutaneous resection device...
  31. LONG-LIVED BLOCKADE OF NA+ CHANNELS BY LOCAL ANESTHETICS
    Kevin Gingrich; Fiscal Year: 2000
    ..Naplus current, and thereby provide important clinical utility in suppressing cardiac arrhythmia s and in local anesthesia. Naplus channels are membrane-spanning proteins that undergo voltage -triggered conformational changes (..
  32. Interleukin 12 Gene Therapy For Colorectal Cancer
    Savio Woo; Fiscal Year: 2003
    ..administered by percutaneous injection into a metastatic tumor in the liver under ultrasound guidance and local anesthesia. The clinical protocol has been approved by the IRB, IBC, FDA, and RAC at the NIH...
  33. PAIN MANAGEMENT IN ALCOHOLICS
    Louis Fiset; Fiscal Year: 1993
    ..among alcoholics in a controlled laboratory setting at baseline and in the presence of peripherally acting local anesthesia and centrally acting nitrous oxide...
  34. Microbiology/Immunology of Periodontal Disease in T1DM
    Paul Moore; Fiscal Year: 2002
    ..An integrated multidisciplinary effort provides significant data collection capabilities essential for understanding the complex multifactorial etiology of periodontal disease in Type 1 diabetes. ..
  35. ORAL HEALTH OF OLDER TYPE 1 DIABETIC PATIENTS
    Paul Moore; Fiscal Year: 2003
    ..This overall plan will permit us to understand the etiology of these complications and to define specific subpopulations and risk factors appropriate for future prospective oral health prevention and intervention trials. ..
  36. MOLECULAR BASIS OF LOCAL ANESTHESIA
    Walter Chazin; Fiscal Year: 2008
    ....
  37. URINE LOSS AND PROLAPSE IN NUNS AND THEIR PAROUS SISTERS
    GUNHILDE BUCHSBAUM; Fiscal Year: 2003
    ..A matched pair logistic regression will be performed to obtain an adjusted estimate of the impact of familiality and vaginal delivery in UT and POP, taking into account other risk factors. ..
  38. The Molecular Basis of Juvenile Polyposis
    James Howe; Fiscal Year: 2005
    ..These studies will also benefit JP patients by improving presymptomatic genetic testing, and identification of new therapeutic targets for polyp regression and cancer prevention in JP. ..
  39. Role of TGF-b In Excessive Scarring: A Cutaneous Model
    Thomas Mustoe; Fiscal Year: 2005
    ..abstract_text> ..
  40. RCT of a Novel Oral Contraceptive Initiation Method
    Carolyn Westhoff; Fiscal Year: 2004
    ..We will also assess dual method use for STD prevention in the study to adoption of and adherence to oral contraceptives. We will also assess dual method use for STD prevention in the study population. ..
  41. Outcomes After ACL Reconstruction: Femoral Nerve Block
    Brian Williams; Fiscal Year: 2005
    ..The methods learned and the model developed herein will be the basis of future studies funded through the R01 mechanism. ..
  42. NEURAL PROCESSING OF COMMUNICATION SOUNDS
    John Crawford; Fiscal Year: 2002
    ..e. phase spectrum) of periodic stimuli. ..
  43. IMPACT OF AGING, ISCHEMIA AND CYTOKINES ON WOUND HEALING
    Thomas Mustoe; Fiscal Year: 2002
    ....
  44. MOLECULAR BASIS OF LIGAND/SODIUM CHANNEL INTERACTIONS
    GING WANG; Fiscal Year: 2002
    ....
  45. CUTANEOUS CONTROL OF EXPLORATORY HAND MOVEMENT
    ALLAN SMITH; Fiscal Year: 2001
    ..Ultimately both the prehension and tactile exploration tasks have promise as diagnostic and therapeutic techniques to aid in rehabilitation medicine with stroke patients and patients with peripheral neuropathies. ..
  46. THE ROLE OF MYCOBACTERIA IN CROHN'S DISEASE
    David Graham; Fiscal Year: 2005
    ..The results of this study should either confirm or refute the proposed etiologic association of M. paratuberculosis and Crohn's disease as well as the identification of patients with Crohn's disease and M. paratuberculosis. ..
  47. Regulation of SMAD4 and BMPR1A Expression in Juvenile Polyposis
    James R Howe; Fiscal Year: 2010
    ..abstract_text> ..
  48. PALLIDAL PHYSIOLOGY IN HUMAN AND PRIMATE DYSTONIA
    PHILIP STARR; Fiscal Year: 2005
    ..Development of an animal model in a large nonhuman primate will open the possibility for further detailed investigations of basal ganglia physiology in dystonia, beyond those which are possible during human surgery. ..
  49. Impact of adolescent pregnancy on nutritional status
    Joanne Katz; Fiscal Year: 2006
    ..Measures of nutritional status at birth include weight, length, head, chest and mid upper arm circumference. Growth of these infants through 6 months of age will also be examined, as will hemoglobin and serum retinol at 3 months of age. ..
  50. Child Obesity Intervention:Feasibility in Dental Setting
    Mary Tavares; Fiscal Year: 2006
    ..Recommendations and referrals (for those with BMI in the 85%ile or higher) will be individualized for each participant. ..
  51. Neural correlates of memory fMR in human cortex.
    George Ojemann; Fiscal Year: 2006
    ..clinical opportunity, patients undergoing surgery for epilepsy with a technique where they are awake under local anesthesia for a portion of the operation...
  52. Development of Sensory/Pain-Selective Local Anesthetics
    Peter Gerner; Fiscal Year: 2006
    ..abstract_text> ..
  53. Cytokine Regulation of Periradicular Pain in Humans
    Asma Khan; Fiscal Year: 2007
    ..Dr Kenneth Kornman of IL Genetics will serve as a consultant on this project and will oversee the genotyping and genetic analysis. Statistical consultation will be provided by Dr. Brad Pollock. ..
  54. Obesity, Oral Contraception and Ovarian Suppression
    Carolyn Westhoff; Fiscal Year: 2007
    ..This study will have very good power to detect clinically important differences. Results could directly and immediately affect contraceptive practice. ..
  55. CLINICAL NEUROSCIENCES TRAINING
    George Ojemann; Fiscal Year: 2008
    ..Four (4) post-doctoral and two (2) pre-doctoral trainees each year are requested, along with three (3) three-month short-term trainees. ..
  56. Acupuncture and Low Back Pain during Pregnancy
    Shu Ming Wang; Fiscal Year: 2007
    ..abstract_text> ..
  57. Menthol, Ethnicity and Nicotine Dependence
    Karen Ahijevych; Fiscal Year: 2007
    ..Findings may inform future tobacco dependence treatment with smokers who prefer menthol cigarettes. ..
  58. PREVALENCE AND IMPACT OF GLAUCOMA AMONG THE VERY ELDERLY
    David Friedman; Fiscal Year: 2003
    ..Finally, the interactions between comorbidities (including cognitive deficits) and visual field loss will be explored. ..
  59. Microbial Outcomes of Minimal Intervention Treatment
    Mathilde Peters; Fiscal Year: 2005
    ..This investigation is a clinical and molecular re-entry study of sealing of caries, in support of a future full-scale clinical trial of incomplete caries removal. ..