Genomes and Genes
Summary: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
Publications325 found, 100 shown here
- Anesthesia in a patient with multiple endocrine abnormalities. Case reportRenato Toledo Maciel
Hospital Universitário Clementino Fraga Filho da Faculdade de Medicina da Universidade Federal do Rio de Janeiro HUCFF UFRJ, Rio de Janeiro, RJ
Rev Bras Anestesiol 58:172-8. 2008..The patient remained hemodynamically stable even during the pneumoperitoneum. She developed postoperative episodes of hypoglycemia, which motivated the re-operation...
- Current practice of preoperative fasting: a nationwide survey in Japanese anesthesia-teaching hospitalsNobuaki Shime
Department of Anesthesiology, Postgraduate School of Medicine, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kamigyo ku, Kyoto, 602 8566, Japan
J Anesth 19:187-92. 2005..conducted a nationwide survey to investigate the current practice of the preoperative fasting period in Japanese anesthesia-teaching hospitals...
- Low degree of anesthesia increases the risk of neurogenic pulmonary edema developmentJ Sedy
Institute of Experimental Medicine, ASCR, Prague, Czech Republic
Med Hypotheses 70:308-13. 2008..We introduce a new hypothesis that high levels of anesthesia might protect the organism against the development of neurogenic pulmonary edema due to a more pronounced ..
- Percutaneous and minimally invasive valve procedures: a scientific statement from the American Heart Association Council on Cardiovascular Surgery and Anesthesia, Council on Clinical Cardiology, Functional Genomics and Translational Biology InterdisciplinTodd K Rosengart
State University of New York Stony Brook, USA
Circulation 117:1750-67. 2008....
- Population imaging of ongoing neuronal activity in the visual cortex of awake ratsDavid S Greenberg
Department of Cell Physiology, Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany
Nat Neurosci 11:749-51. 2008..b>Anesthesia modulated population-wide synchronization and the relationship between firing rate and correlation...
- Society for Ambulatory Anesthesia guidelines for the management of postoperative nausea and vomitingTong J Gan
Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
Anesth Analg 105:1615-28, table of contents. 2007..and expertise in postoperative nausea and vomiting (PONV) under the auspices of The Society of Ambulatory Anesthesia. The panel critically evaluated the current medical literature on PONV to provide an evidence-based reference ..
- Serotonin-mushroom body circuit modulating the formation of anesthesia-resistant memory in DrosophilaPei Tseng Lee
Department of Life Science, National Tsing Hua University, Hsinchu 30013, Taiwan
Proc Natl Acad Sci U S A 108:13794-9. 2011Pavlovian olfactory learning in Drosophila produces two genetically distinct forms of intermediate-term memories: anesthesia-sensitive memory, which requires the amnesiac gene, and anesthesia-resistant memory (ARM), which requires the ..
- Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermiaEmmanuel Planel
Columbia University Medical Center, Department of Pathology, Taub Institute for Alzheimer s Disease Research, New York, New York 10032, USA
J Neurosci 27:3090-7. 2007Postoperative cognitive dysfunction, confusion, and delirium are common after general anesthesia in the elderly, with symptoms persisting for months or years in some patients...
- Propofol anesthesia and sleep: a high-density EEG studyMichael Murphy
Department of Psychiatry, University of Wisconsin Madison, Madison, WI 53719, USA
Sleep 34:283-91A. 2011..We used high-density electroencephalography (hd-EEG) and source modeling to investigate the cortical processes underlying propofol anesthesia and compare them to sleep.
- Effect of carbon dioxide pneumoperitoneum on development of atelectasis during anesthesia, examined by spiral computed tomographyLena E Andersson
Department of Anesthesiology and Intensive Care, Karolinska University Hospital, Huddinge, Sweden
Anesthesiology 102:293-9. 2005b>Anesthesia per se results in atelectasis development in the dependent regions of the lungs. The effect of pneumoperitoneum on atelectasis formation is not known...
- Anesthesia for a patient with morbid obesity using dexmedetomidine without narcoticsRoger E Hofer
Department of Anesthesiology, Mayo Clinic College of Medicine, 200 First Street S W, Rochester, MN 55905, USA
Can J Anaesth 52:176-80. 2005..To describe the anesthetic management of a patient with extreme obesity undergoing bariatric surgery whose intraoperative narcotic management was entirely substituted with dexmedetomidine...
- The incidence and nature of adverse events during pediatric sedation/anesthesia with propofol for procedures outside the operating room: a report from the Pediatric Sedation Research ConsortiumJoseph P Cravero
Department of Anesthesiology and Pediatrics, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756 0001, USA
Anesth Analg 108:795-804. 2009We used a large database of prospectively collected data on pediatric sedation/anesthesia outside the operating room provided by a wide range of pediatric specialists to delineate the nature and frequency of adverse events associated with ..
- Stable and dynamic cortical electrophysiology of induction and emergence with propofol anesthesiaJonathan D Breshears
Washington University School of Medicine, St Louis, MO 63110, USA
Proc Natl Acad Sci U S A 107:21170-5. 2010..comprehensive recording of invasive human cortical physiology during both induction and emergence from propofol anesthesia. Propofol-induced transitions in and out of consciousness (defined here as responsiveness) were characterized by ..
- Early childhood exposure to anesthesia and risk of developmental and behavioral disorders in a sibling birth cohortCharles DiMaggio
Department of Anesthesiology, Columbia University, 622 West 168 St, New York, NY 10032, USA
Anesth Analg 113:1143-51. 2011..However, the clinical relevance of these findings to children undergoing anesthesia remains unclear...
- Nerve injury associated with anesthesia: a closed claims analysisF W Cheney
Department of Anesthesiology, University of Washington School of Medicine, Seattle 98195, USA
Anesthesiology 90:1062-9. 1999Nerve injury associated with anesthesia is a significant source of morbidity for patients and liability for anesthesiologists...
- Microcirculatory alterations in cardiac surgery: effects of cardiopulmonary bypass and anesthesiaDaniel De Backer
Department of Intensive Care, Erasme Hospital, Free University of Brussels, Brussels, Belgium
Ann Thorac Surg 88:1396-403. 2009..Heterogeneity in microvascular perfusion is associated with impaired tissue oxygenation. We hypothesized that cardiac surgery with or without cardiopulmonary bypass (CPB) could induce microvascular alterations...
- Visualization of murine intranasal dosing efficiency using luminescent Francisella tularensis: effect of instillation volume and form of anesthesiaMark A Miller
The University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
PLoS ONE 7:e31359. 2012..delivery via intranasal dosing performed either with differing instillation volumes or different types of anesthesia. FTLVS was rendered luminescent via transformation with a reporter plasmid that constitutively expressed the ..
- Signaling at A-kinase anchoring proteins organizes anesthesia-sensitive memory in DrosophilaMartin Schwaerzel
Saarland University, Faculty 8 3 Life Science, Department of Zoology and Physiology, 66041 Saarbrucken, Germany
J Neurosci 27:1229-33. 2007..Together, our results show that subcellular organization of signaling components plays a key role in memory processing...
- Cyclic and sleep-like spontaneous alternations of brain state under urethane anaesthesiaElizabeth A Clement
Centre for Neuroscience, University of Alberta, Edmonton, Alberta, Canada
PLoS ONE 3:e2004. 2008....
- Update on tracheobronchial anatomy and flexible fiberoptic bronchoscopy in thoracic anesthesiaJavier H Campos
Department of Anesthesia, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
Curr Opin Anaesthesiol 22:4-10. 2009This review is focused on tracheobronchial anatomy and the use of flexible fiberoptic bronchoscopy in thoracic anesthesia.
- Anesthesia and the old brainJunxia Tang
Department of Anesthesiology and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Anesth Analg 110:421-6. 2010..In this special article, we summarize the rationale and evidence that the anesthetic per se is a contributor. The evidence at this point is considered suggestive and further research is needed, especially in humans...
- The entwined mysteries of anesthesia and consciousness: is there a common underlying mechanism?Stuart R Hameroff
Department of Anesthesiology, The University of Arizona, Tucson, Arizona 85718, USA
Anesthesiology 105:400-12. 2006
- Successful small intestine colonization of adult mice by Vibrio cholerae requires ketamine anesthesia and accessory toxinsVerena Olivier
Department of Microbiology Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
PLoS ONE 4:e7352. 2009..Successful colonization was found to depend upon anesthesia with ketamine-xylazine and neutralization of stomach acid with sodium bicarbonate, but not streptomycin ..
- The use of an anesthesia information management system for prediction of antiemetic rescue treatment at the postanesthesia care unitA Junger
Department of Anesthesiology and Intensive Care Medicine, Justus Liebig University, Rudolf Buchheim Str 7, D 35392 Giessen, Germany
Anesth Analg 92:1203-9. 2001We used an anesthesia information management system (AIMS) to devise a score for predicting antiemetic rescue treatment as an indicator for postoperative nausea and vomiting (PONV) in the postanesthesia care unit (PACU)...
- Anaphylaxis during anesthesia in Norway: a 6-year single-center follow-up studyTorkel Harboe
Department of Anesthesia and Intensive Care, Haukeland University Hospital, Bergen, Norway
Anesthesiology 102:897-903. 2005..studies have recognized neuromuscular blocking agents as the most common cause of anaphylaxis during general anesthesia, but the reported frequencies vary considerably between countries...
- Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouseMihail G Chelu
Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA
FASEB J 20:329-30. 2006..We conclude that the heterozygous expression of the Y522S mutation confers susceptibility to both heat- and anesthetic-induced MH responses...
- Less core hypothermia when anesthesia is induced with inhaled sevoflurane than with intravenous propofolT Ikeda
Department of Anesthesiology and Intensive Care, Hamamatsu University School of Medicine, Japan
Anesth Analg 88:921-4. 1999Hypothermia after the induction of anesthesia results initially from core-to-peripheral redistribution of body heat. Sevoflurane and propofol both inhibit central thermoregulatory control, thus causing vasodilation...
- Stimulus onset quenches neural variability: a widespread cortical phenomenonMark M Churchland
Department of Electrical Engineering, Stanford University School of Medicine, Stanford University, Stanford, California, USA
Nat Neurosci 13:369-78. 2010..This widespread variability decline suggests a rather general property of cortex, that its state is stabilized by an input...
- Consensus statement: First International Workshop on Anesthetics and Alzheimer's diseaseDmitri Baranov
Department of Anesthesiology and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Anesth Analg 108:1627-30. 2009In order to review the current status of the potential relationship between anesthesia and Alzheimer's disease, a group of scientists recently met in Philadelphia for a full day of presentations and discussions...
- Evaluation of anesthesia effects on [18F]FDG uptake in mouse brain and heart using small animal PETHiroshi Toyama
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
Nucl Med Biol 31:251-6. 2004This study evaluates effects of anesthesia on (18)F-FDG (FDG) uptake in mouse brain and heart to establish the basic conditions of small animal PET imaging...
- Anesthesia induces neuronal cell death in the developing rat brain via the intrinsic and extrinsic apoptotic pathwaysJ H Yon
Department of Anesthesiology, University of Virginia Health System, P O Box 800710, Charlottesville, VA 22908, USA
Neuroscience 135:815-27. 2005..We found that the intrinsic pathway is activated early on during anesthesia exposure (within two hours), as measured by the down-regulation of bcl-x(L), up-regulation of cytochrome c and ..
- Deletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesisAnnette Robichaud
Merck Frosst Centre for Therapeutic Research, Pointe Claire Dorval, Quebec, Canada
J Clin Invest 110:1045-52. 2002..of type 4 cAMP-specific cyclic nucleotide phosphodiesterase 4 (PDE4) in reversing alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesis in non-vomiting species...
- Prevention and treatment of postoperative nausea and vomitingA L Kovac
Department of Anaesthesiology, University of Kansas Medical Center, Kansas City 66160 7415, USA
Drugs 59:213-43. 2000....
- Assessing cortico-hippocampal functional connectivity under anesthesia and kainic acid using generalized partial directed coherenceJiannis Taxidis
School of Mathematical Sciences, University of Nottingham, Nottingham, NG7 2RD, UK
Biol Cybern 102:327-40. 2010..medial prefrontal cortex (mPFC) and hippocampus and within the hippocampus of the rat brain, under isoflurane anesthesia and kainic acid-induced enhanced neuronal activity...
- Human Alzheimer and inflammation biomarkers after anesthesia and surgeryJunxia X Tang
Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Anesthesiology 115:727-32. 2011..The authors studied human cerebrospinal fluid (CSF) biomarkers during surgery...
- Neuronal synchrony during anesthesia: a thalamocortical modelJane H Sheeba
Department of Physics, Lancaster University, Lancaster LA1 4YB, United Kingdom
Biophys J 95:2722-7. 2008..The theta- and delta-rhythms are shown to be involved in various sleep stages, and during anesthesia, they undergo changes with the depth of anesthesia...
- Biomarkers of acute kidney injury in anesthesia, intensive care and major surgery: from the bench to clinical research to clinical practiceE Moore
Department of Epidemiology and Preventive Medicine, Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia
Minerva Anestesiol 76:425-40. 2010..These biomarkers have many potential applications during anesthesia and in the ICU...
- Anesthesia for nonobstetric surgery: maternal and fetal considerationsTheodore G Cheek
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
Clin Obstet Gynecol 52:535-45. 2009This monograph will review and update our understanding of the administration of anesthesia for nonobstetric surgery and its maternal and fetal effects...
- Cognitive and behavioral outcomes after early exposure to anesthesia and surgeryRandall P Flick
Department of Anesthesiology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Pediatrics 128:e1053-61. 2011..the possible significance of these findings in children, we investigated the association between exposure to anesthesia and subsequent (1) learning disabilities (LDs), (2) receipt of an individualized education program for an ..
- Factors predictive of patient satisfaction with anesthesiaMaurizia Capuzzo
Department of Surgical, Anesthetic and Radiological Sciences, Section of Anesthesiology and Intensive Care, University Hospital of Ferrara, Ferrara, Italy
Anesth Analg 105:435-42. 2007In this multicenter prospective study, we identified factors associated with satisfaction with anesthesia in patients staying in hospital at least 24 h after surgery.
- Cortical inhibition during burst suppression induced with isoflurane anesthesiaJudy Fay Ferron
Department of Stomatology, School of Medical Dentistry, Universite de Montreal, Montreal, Quebec H3C 3J7, Canada
J Neurosci 29:9850-60. 2009..Thus cortical hyperexcitability during BS is favored by suppressed inhibition...
- Reducing the risk of anaphylaxis during anesthesia: 2011 updated guidelines for clinical practiceP M Mertes
Service d Anesthésie Réanimation Chirurgicale Inserm U911, CHU de Nancy, Hopital Central, Nancy, France
J Investig Allergol Clin Immunol 21:442-53. 2011..represent the updated consensus of experts in the field of immediate hypersensitivity reactions occurring during anesthesia. They provide a series of valid, widely accepted, effective, and easily teachable guidelines that are the fruit ..
- Pathomechanisms and complications related to patient positioning and anesthesia during shoulder arthroscopyDerek D Rains
Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, 98195 4060, USA
Arthroscopy 27:532-41. 2011..the reports and studies documenting independent and dependent complications related to patient positioning and anesthesia during arthroscopic shoulder surgery...
- Anesthesia-related cardiac arrest in children with heart disease: data from the Pediatric Perioperative Cardiac Arrest (POCA) registryChandra Ramamoorthy
Department of Anesthesiology, S tanford University School of Medicine, Stanford, California, USA
Anesth Analg 110:1376-82. 2010From 1994 to 2005, the Pediatric Perioperative Cardiac Arrest Registry collected data on 373 anesthesia-related cardiac arrests (CAs) in children, 34% of whom had congenital or acquired heart disease (HD).
- The incidence and risk factors for hypotension after spinal anesthesia induction: an analysis with automated data collectionBernd Hartmann
Department of Anesthesiology and Intensive Care Medicine, Justus Liebig University Giessen, Rudolf Buchheim Strasse 7, D 35392 Giessen, Germany
Anesth Analg 94:1521-9, table of contents. 2002We sought to identify factors that are associated with hypotension after the induction of spinal anesthesia (SpA) by using an anesthesia information management system...
- Influence of a brief episode of anesthesia during the induction of experimental brain trauma on secondary brain damage and inflammationClara Luh
Department of Anesthesiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany
PLoS ONE 6:e19948. 2011It is unclear whether a single, brief, 15-minute episode of background anesthesia already modulates delayed secondary processes after experimental brain injury...
- Anesthesia in the patient with multiple drug allergies: are all allergies the same?Pascale Dewachter
Pôle d Anesthésie Réanimation, Hopital Gabriel Montpied, Clermont Ferrand, France
Curr Opin Anaesthesiol 24:320-5. 2011..The aim of this review is to facilitate the recognition of risk factors for perioperative anaphylaxis and help the management of patients with 'multiple drug allergies' during the perioperative period...
- Anesthetic modulation of neuroinflammation in Alzheimer's diseaseJunxia X Tang
Department of Anesthesiology and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Curr Opin Anaesthesiol 24:389-94. 2011To summarize key studies and recent thought on the role of neuroinflammation in chronic neurodegeneration, and whether it can be modulated by anesthesia and surgery.
- Epidemiology of anesthesia-related mortality in the United States, 1999-2005Guohua Li
Center for Health Policy and Outcomes in Anesthesia and Critical Care, Department of Anesthesiology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Anesthesiology 110:759-65. 2009Previous research on anesthesia-related mortality in the United States was limited to data from individual hospitals. The purpose of this study was to examine the epidemiologic patterns of anesthesia-related deaths at the national level.
- Influence of anesthesia on cerebral blood flow, cerebral metabolic rate, and brain functional connectivityVincent Bonhomme
University Department of Anesthesia and ICM, CHR Citadelle, Belgium
Curr Opin Anaesthesiol 24:474-9. 2011To describe recent studies exploring brain function under the influence of hypnotic anesthetic agents, and their implications on the understanding of consciousness physiology and anesthesia-induced alteration of consciousness.
- Bispectral index-guided administration of anesthesia for transsphenoidal resection of pituitary tumors: a comparison of 3 anesthetic techniquesZulfiqar Ali
Department of Neuroanaesthesiology, Neurosciences Center, All India Institute of Medical Sciences, New Delhi, India
J Neurosurg Anesthesiol 21:10-5. 2009The main aims of anesthesia for pituitary surgery include maintenance of hemodynamic stability, provision of conditions that facilitate surgical exposure, and a smooth emergence to facilitate a prompt neurologic assessment...
- Safety and efficacy of various combinations of injectable anesthetics in BALB/c miceSandra Buitrago
Department of Laboratory Animal Resources, Roswell Park Cancer Institute, Buffalo, NY, USA
J Am Assoc Lab Anim Sci 47:11-7. 2008..ketamine-xylazine-buprenorphine, and ketamine-xylazine-carprofen--were compared for their ability to produce anesthesia in BALB/c mice...
- Anesthesia for thoracic surgery in morbidly obese patientsJens Lohser
Department of Anesthesiology, Stanford University School of Medicine, Stanford, California, USA
Curr Opin Anaesthesiol 20:10-4. 2007..Obese patients have altered anatomy and physiology, and usually have associated comorbid medical conditions that may complicate their operative course and increase their risks for postoperative complications...
- Redesigning a morbidity and mortality program in a university-affiliated pediatric anesthesia departmentConor McDonnell
Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto
Jt Comm J Qual Patient Saf 36:117-25. 2010..The M&M activities were developed in a university-affiliated pediatric anesthesia department as part of a departmental quality improvement (QI) initiative...
- A protocol for use of medetomidine anesthesia in rats for extended studies using task-induced BOLD contrast and resting-state functional connectivityChristopher P Pawela
Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Neuroimage 46:1137-47. 2009..In the secondary infusion period using 300 microg/kg/h, resting-state functional connectivity is enhanced...
- Oxygen in neonatal anesthesia: friend or foe?Augusto Sola
Mid Atlantic Neonatology Associates and Atlantic Neonatal Research Institute, Morristown, NJ 07960, USA
Curr Opin Anaesthesiol 21:332-9. 2008..Hypoxemia is due to many pathophysiological causes; avoiding hypoxemia is an important objective during neonatal anesthesia. Nevertheless, the only known cause for hyperoxemia is the excess and unnecessary administration of oxygen by ..
- Use of in-office anesthesia during non-surgical radiofrequency collagen denaturation for stress urinary incontinenceW Glen Wells
Alabama Research Center, Birmingham, AL 35209, USA
Curr Med Res Opin 23:1279-84. 2007..This multicenter trial aimed to demonstrate the feasibility, safety, and efficacy of an oral sedation and local anesthetic regimen in performing RF collagen denaturation...
- Impact of anesthesia on transcranial electric motor evoked potential monitoring during spine surgery: a review of the literatureAnthony C Wang
Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan 48109 5338, USA
Neurosurg Focus 27:E7. 2009..b>Anesthesia, however, can significantly affect the reliability of TcMEP monitoring...
- The effects of carbon dioxide anesthesia and anoxia on rapid cold-hardening and chill coma recovery in Drosophila melanogasterTheresa L Nilson
Department of Biological Sciences University of Nevada, Las Vegas, NV 89154 4004, USA
J Insect Physiol 52:1027-33. 2006..Exposure to CO(2) anesthesia increases chill coma recovery time, but this effect disappears if the flies are given 90 min recovery in air ..
- The effects of sevoflurane and desflurane anesthesia on QTc interval and cardiac rhythm in childrenEbru Aypar
Section of Pediatric Cardiology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey
Paediatr Anaesth 17:563-7. 2007..We assessed the effects of desflurane anesthesia on QTc interval and cardiac rhythm and compared them with sevoflurane anesthesia in children.
- Temporal scaling properties and spatial synchronization of spontaneous blood oxygenation level-dependent (BOLD) signal fluctuations in rat sensorimotor network at different levels of isoflurane anesthesiaKun Wang
LIAMA Center for Computational Medicine, National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China
NMR Biomed 24:61-7. 2011..In order to obtain more insights into this relationship and, in particular, the effects of anesthesia thereupon, we investigated the spatial and temporal correlations of spontaneous BOLD fluctuations in ..
- Bruchpilot, a synaptic active zone protein for anesthesia-resistant memoryStephan Knapek
Max Planck Institut fur Neurobiologie, 82152 Martinsried, Germany
J Neurosci 31:3453-8. 2011..We further demonstrate that Brp in the Kenyon cells preferentially functions for anesthesia-resistant memory...
- Anesthesia for patients with congenital long QT syndromeSusan J Kies
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Anesthesiology 102:204-10. 2005..Certain drugs, including anesthetic agents, are known to contribute to QT prolongation. After reviewing the literature the authors give recommendations for the anesthetic management of these patients in the perioperative period...
- Anesthesia and its allied disciplines in the developing world: a nationwide survey of the Republic of ZambiaStefan Jochberger
Department of Anesthesiology and Critical Care Medicine, Innsbruck Medical University, Innsbruck, Austria
Anesth Analg 106:942-8, table of contents. 2008..To improve survival of acutely and critically ill patients in these countries, basic problems and demands of anesthesia care need to be identified...
- The role of nicotinic acetylcholine receptors in the mechanisms of anesthesiaEdomer Tassonyi
Division of Anesthesiology, Department of Anesthesiology, Pharmacology and Surgical Intensive Care APSIC, Geneva University Hospitals, Geneva, Switzerland
Brain Res Bull 57:133-50. 2002..Although nicotinic acetylcholine receptors are not directly involved in the hypnotic component of anesthesia, it is possible that modulation of central nicotinic transmission by volatile agents contributes to analgesia...
- Anesthesia-induced developmental neuroapoptosis. Does it happen in humans?John W Olney
Anesthesiology 101:273-5. 2004
- Anesthesia can cause sustained hyperglycemia in C57/BL6J miceE T Brown
Center for Vision Research, SUNY Upstate Medical University, Syracuse, NY 13210, USA
Vis Neurosci 22:615-8. 2005Effects of anesthesia on the blood glucose of C57/BL6J mice were evaluated under conditions commonly used for testing retinal sensitivity with electroretinographic (ERG) recordings...
- Clinical anesthesia causes permanent damage to the fetal guinea pig brainSabina Rizzi
Department of Anesthesiology, University of Virginia Health System, Charlottesville, VA 22908, USA
Brain Pathol 18:198-210. 2008Exposure of the immature brain to general anesthesia is common. The safety of this practice has recently been challenged in view of evidence that general anesthetics can damage developing mammalian neurons...
- New developments in pediatric cardiac anesthesiaLaura K Diaz
The Arthur S Keats Division of Pediatric Cardiovascular Anesthesiology, Texas Children s Hospital, Houston, TX 77030, USA
Anesthesiol Clin North America 23:655-76, viii. 2005As the practice of pediatric cardiac anesthesia continues to grow, anesthesiologists now routinely care for patients ranging in size from less than 2 kg to more than 100 kg...
- Weak intermolecular associations and anesthesiaCamille Sandorfy
Departement de Chimie, Universite de Montreal, Montreal, Quebec
Anesthesiology 101:1225-7. 2004
- How depth of anesthesia influences the blood oxygenation level-dependent signal from the visual cortex of childrenV L Marcar
Department of Neuropsychology, University of Zurich, Zurich, Switzerland
AJNR Am J Neuroradiol 27:799-805. 2006..MR imaging in young children or infants frequently involves measuring a clinical population under sedation or anesthesia. We examined the effect of depth of anesthesia on the extent and amplitude of the blood oxygen level-dependent (..
- A retrospective cohort study of the association of anesthesia and hernia repair surgery with behavioral and developmental disorders in young childrenCharles DiMaggio
Department of Epidemiology, Mailman School of Public Health, New York, NY, USA
J Neurosurg Anesthesiol 21:286-91. 2009..of the potential association of surgery and its concurrent exposure to anesthetic agents with neurotoxicity and underscore the need for more rigorous clinical research on the long-term effects of surgery and anesthesia in children.
- Angiotensin-converting enzyme inhibitors: mechanisms of action and implications in anesthesia practiceRahim Behnia
Department of Anesthesiology and Pain Management, John H Stroger Jr Hospital of Cook County, Chicago, IL 60612, USA
Curr Pharm Des 9:763-76. 2003..their possible interaction with anesthetic agents must be an integral part of clinical decision-making during anesthesia Hemodynamic variation during anesthesia is mainly related to specific effects of anesthetic agents on ..
- Contralateral hand anesthesia transiently improves poststroke sensory deficitsBernhard Voller
Human Cortical Physiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
Ann Neurol 59:385-8. 2006..To test a possible strategy to alleviate somatosensory deficits after stroke...
- Anesthetic management and one-year mortality after noncardiac surgeryTerri G Monk
Department of Anesthesiology Duke University Medical Center, Durham, NC 27705, USA
Anesth Analg 100:4-10. 2005..We designed a prospective observational study of adult patients undergoing major noncardiac surgery with general anesthesia to determine if mortality in the first year after surgery is associated with demographic, preoperative clinical, ..
- Development of a measure of patient satisfaction with monitored anesthesia care: the Iowa Satisfaction with Anesthesia ScaleF Dexter
Department of Anesthesia, University of Iowa, Iowa City 52242, USA
Anesthesiology 87:865-73. 1997The authors describe development of the Iowa Satisfaction with Anesthesia Scale (ISAS) for monitored anesthesia care (MAC). Patients complete the self-administered written questionnaire before discharge from the hospital...
- The effects of pentobarbital, fentanyl-droperidol, ketamine-xylazine and ketamine-diazepam on arterial blood pH, blood gases, mean arterial blood pressure and heart rate in adult male ratsS K Wixson
Department of Comparative Medicine, Milton S Hershey Medical Center, Pennsylvania State University, Hershey 17033
Lab Anim Sci 37:736-42. 1987..Throughout all dosages investigated, the ketamine-diazepam combination showed the least overall effects on ventilation and perfusion of the four parenteral drug combinations studied...
- Distress during the induction of anesthesia and postoperative behavioral outcomesZ N Kain
Department of Anesthesiology, Yale School of Medicine, New Haven, Connecticut, USA
Anesth Analg 88:1042-7. 1999We determined whether children who are extremely anxious during the induction of anesthesia are more at risk of developing postoperative negative behavioral changes compared with children who appear calm during the induction process...
- Trends in anesthesia-related death and brain damage: A closed claims analysisFrederick W Cheney
Department of Anesthesiology, University of Washington, School of Medicine, Seattle, WA 98195 6540, USA
Anesthesiology 105:1081-6. 2006....
- Cellular and network mechanisms of slow oscillatory activity (<1 Hz) and wave propagations in a cortical network modelAlbert Compte
Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts 02454, USA
J Neurophysiol 89:2707-25. 2003Slow oscillatory activity (<1 Hz) is observed in vivo in the cortex during slow-wave sleep or under anesthesia and in vitro when the bath solution is chosen to more closely mimic cerebrospinal fluid...
- Educating patients about anesthesia: a systematic review of randomized controlled trials of media-based interventionsAnna Lee
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, China
Anesth Analg 96:1424-31, table of contents. 2003In this systematic review, we compared the effectiveness of media-based patient education about anesthesia. Fifteen randomized controlled trials (n = 1506) were identified after a systematic search of electronic databases (MEDLINE, EMBASE,..
- Integration and segregation of activity in entorhinal-hippocampal subregions by neocortical slow oscillationsYoshikazu Isomura
Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, New Jersey 07102, USA
Neuron 52:871-82. 2006..Thus, neo/paleocortical and hippocampal networks periodically reset, self-organize, and temporally coordinate their cell assemblies via the slow oscillation...
- Muscle relaxation does not alter hypnotic level during propofol anesthesiaRobert Greif
Department of Anesthesiology and Intensive Care Medicine, Donauspital SMZO, Vienna, Austria
Anesth Analg 94:604-8; table of contents. 2002..BIS averaged 95 plus/minus 4 before induction of anesthesia, and decreased significantly to 40 plus/minus 5 after propofol administration...
- Anesthesia for electroconvulsive therapyZhengnian Ding
Department of Anesthesiology and Pain Management, First Affiliated Hospital of Nanjing Medical University, China
Anesth Analg 94:1351-64. 2002
- Reactive oxygen species as mediators of cardiac injury and protection: the relevance to anesthesia practiceLeo G Kevin
Anesthesiology Research Laboratories, 8701 Watertown Plank Road, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Anesth Analg 101:1275-87. 2005..The sources of ROS, the means by which they induce cardiac injury or activate protective signaling pathways, the results of clinical studies evaluating ROS scavengers, and the effects of anesthetic drugs on ROS are each discussed...
- Non-invasive intraoperative monitoring of blood pressure and arterial pCO2 during surgical anesthesia in miceSerge C Thal
Institute for Surgical Research, University of Munich Medical Center, Grosshadern, Munich, Germany
J Neurosci Methods 159:261-7. 2007..Thereby the current study may help to reduce animal numbers and perform mice experiments under more defined and controlled physiological conditions in the future...
- Anesthesia and other considerations for in vivo imaging of small animalsIsabel J Hildebrandt
Department of Molecular and Medical Pharmacology at the David Geffen School of Medicine at the University of California, Los Angeles, CA 90095 6942, USA
ILAR J 49:17-26. 2008..In contrast to human studies, however, imaging of small animals generally requires anesthesia, and anesthetic agents can have unintended effects on animal physiology that may confound the results of the ..
- Rocuronium versus succinylcholine for rapid sequence induction of anesthesia and endotracheal intubation: a prospective, randomized trial in emergent casesMathias Sluga
Department of Anesthesia, Krankenhaus Thusis, Switzerland
Anesth Analg 101:1356-61. 2005When anesthesia is induced with propofol in elective cases, endotracheal intubation conditions are not different between succinylcholine and rocuronium approximately 60 s after the injection of the neuromuscular relaxant...
- Brain-state- and cell-type-specific firing of hippocampal interneurons in vivoThomas Klausberger
MRC Anatomical Neuropharmacology Unit, Department of Pharmacology, Oxford University, Mansfield Road, Oxford OX1 3TH, UK
Nature 421:844-8. 2003..We conclude that the diversity of interneurons, innervating distinct domains of pyramidal cells, emerged to coordinate the activity of pyramidal cells in a temporally distinct and brain-state-dependent manner...
- Anesthesia and cognitive performance in children: no evidence for a causal relationshipMeike Bartels
Department of Biological Psychology, VU University, Amsterdam, The Netherlands
Twin Res Hum Genet 12:246-53. 2009Recent findings of an association between anesthesia administration in the first three years of life and later learning disabilities have created concerns that anesthesia has neurotoxic effects on synaptogenesis, causing later learning ..
- Systematic review of questionnaires measuring patient satisfaction in ambulatory anesthesiaPratamaporn Chanthong
Department of Anesthesia, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Canada
Anesthesiology 110:1061-7. 2009Patient satisfaction has become an important component of quality improvement in ambulatory anesthesia services. However, it is difficult to measure due to its subjective and complex psychological construct...
- Auditory cortical neuron response differences under isoflurane versus pentobarbital anesthesiaS W Cheung
W M Keck Center for Integrative Neuroscience, Department of Otolaryngology, University of California, San Francisco 94143 0342, USA
Hear Res 156:115-27. 2001..of feline primary auditory cortex neurons to simple sounds were compared for isoflurane versus pentobarbital anesthesia in a within subject study control design...
- Positioning the morbidly obese patient for anesthesiaJay B Brodsky
Department of Anesthesia, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
Obes Surg 12:751-8. 2002..An understanding of the physiologic changes that can occur is essential for the successful management of these patients...
- Electroencephalographic order pattern analysis for the separation of consciousness and unconsciousness: an analysis of approximate entropy, permutation entropy, recurrence rate, and phase coupling of order recurrence plotsDenis Jordan
Department of Anesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Germany
Anesthesiology 109:1014-22. 2008..g., approximate entropy, have been suggested as measures of the hypnotic component of anesthesia. Compared with linear methods, they may detect additional information and quantify the irregularity of a ..
- Anesthesia condition for (18)F-FDG imaging of lung metastasis tumors using small animal PETSang Keun Woo
Division of Nuclear Medicine and RI Application, Korea Institute of Radiological and Medical Sciences KIRAMS, Nowon Gu, Seoul 139 706, South Korea
Nucl Med Biol 35:143-50. 2008..The aim of this study was to establish the anesthesia condition for imaging of lung metastasis tumor using small animal (18)F-FDG PET.
- Induction of anesthesia and insertion of a laryngeal mask airway in the prone position for minor surgeryAlexander Ng
University Department of Anaesthesia, Critical Care and Pain Management, University Hospitals of Leicester, NHS Trust, Leicester Royal Infirmary, Leicester, England
Anesth Analg 94:1194-8, table of contents. 2002..of the prone position for surgery presents potential obstacles to rapid tracking of patients during ambulatory anesthesia. We describe a prospective audit of 73 patients who placed themselves in the prone position; anesthesia was ..
- Anesthesia and neurodevelopment in children: time for an answer?Lena S Sun
Department of Anesthesiology and Pediatrics, Columbia University, New York, NY, USA
Anesthesiology 109:757-61. 2008
- Plasma concentrations of neuroactive steroids before and after electroconvulsive therapy in major depressionThomas C Baghai
Department of Psychiatry and Psychotherapy, Ludwig Maximilian University of Munich, Munich, Germany
Neuropsychopharmacology 30:1181-6. 2005....
- Fatal and non fatal cardiac arrests related to anesthesiaP Biboulet
Department of Anesthesiology and Critical Care A, Lapeyronie University Hospital, Montpellier, France
Can J Anaesth 48:326-32. 2001The aim of this study was to assess the incidence and causes of cardiac arrests related to anesthesia.
- Anesthesia-related cardiac arrest in children: update from the Pediatric Perioperative Cardiac Arrest RegistrySanjay M Bhananker
Department of Anesthesiology, University of Washington School of Medicine, Seattle, WA, USA
Anesth Analg 105:344-50. 2007..Changes in pediatric anesthesia practice may have altered the causes of cardiac arrest in anesthetized children.
- Injury and liability associated with monitored anesthesia care: a closed claims analysisSanjay M Bhananker
Department of Anesthesiology, University of Washington, Virginia Mason Medical Center, Seattle, WA 98195, USA
Anesthesiology 104:228-34. 2006To assess the patterns of injury and liability associated with monitored anesthesia care (MAC) compared with general and regional anesthesia, the authors reviewed closed malpractice claims in the American Society of Anesthesiologists ..
- Mechanisms of anesthetic effects on tachykinin induced airway toneCharles Emala; Fiscal Year: 2007..1 million from COPD. An increasing number of patients with these diseases require anesthesia and bronchospasm especially during induction and emergence from anesthesia carries significant morbidity...
- Etomidate Analogues as Safer General AnestheticsDouglas E Raines; Fiscal Year: 2010..S. alone, nearly 30 million general anesthetics are administered each year. At the doses required to produce anesthesia, all general anesthetics produce serious side effects...
- Mechanisms of anesthetic effects on tachykinin induced airway toneCharles W Emala; Fiscal Year: 2010..1 million from COPD. An increasing number of patients with these diseases require anesthesia and bronchospasm especially during induction and emergence from anesthesia carries significant morbidity...
- Neuromuscular blocker-induced asthma during anesthesiaCharles Emala; Fiscal Year: 2006..It was developed specifically to facilitate tracheal intubation during the induction of general anesthesia, but has been associated with life threatening bronchospasm...
- Outcomes After ACL Reconstruction: Femoral Nerve BlockBrian Williams; Fiscal Year: 2005..In the proposed project, the applicant aims to develop expertise in clinical trials to measure outcomes after anesthesia and pain management for common orthopedic procedures...
- BRAIN METABOLISM DURING ANESTHESIA, LOW PH1, AND HYPOXIALawrence Litt; Fiscal Year: 1993..The anesthetic effect on "critical oxygen levels" will be examined by repeating the studies for issue #2 during anesthesia with halothane, isoflurane, and thiopental. 4...
- The Role of the Amygdala in Anesthetic-Induced AmnesiaMICHAEL ALKIRE; Fiscal Year: 2006..Understanding anesthesia requires understanding both phenomenon...
- Multimodal Functional Imaging of Auditory Perception Under General AnesthesiaPATRICK PURDON; Fiscal Year: 2007A fundamental problem in neuroscience and medicine is to understand the mechanisms of general anesthesia. This proposal, "Multimodal Functional Imaging of Auditory Perception Under General Anesthesia", is submitted in response to the ..
- Anesthesia-induced Developmental NeuroapoptosisVesna Jevtovic Todorovic; Fiscal Year: 2009Exposure of premature infants, neonates and very young children to general anesthesia is a frequent occurrence in modern medicine...
- Anesthesia-induced Developmental NeuroapoptosisVesna Jevtovic Todorovic; Fiscal Year: 2007Exposure of premature infants, neonates and very young children to general anesthesia is a frequent occurrence in modern medicine...
- Anesthesia-induced Developmental NeuroapoptosisVesna Jevtovic Todorovic; Fiscal Year: 2009Exposure of premature infants, neonates and very young children to general anesthesia is a frequent occurrence in modern medicine...
- The Role of the Amygdala in Anesthetic-Induced AmnesiaMICHAEL ALKIRE; Fiscal Year: 2003..Understanding anesthesia requires understanding both phenomenon...
- ACUTE TOLERANCE IN ANESTHETIC ACTIONS AND INTERACTIONSIgor Kissin; Fiscal Year: 2001..may provide different outcomes (addition, synergism, or antagonism) regarding different components of anesthesia (e.g., unconsciousness or immobility to noxious stimulation)...
- Neonatal Anesthetic NeurotoxicityPiyush M Patel; Fiscal Year: 2010A premise of general anesthesia is that anesthetics produce a non-toxic and reversible state of unconsciousness...
- Arousal, orexins and anesthesiaMAX KELZ; Fiscal Year: 2007..anesthetics varies across a population with some individuals requiring a higher dose to achieve a given depth of anesthesia. Anesthetic resistance may present in humans as awareness under anesthesia...
- Isoflurane: Identification of Key New TargetsAaron Fox; Fiscal Year: 2009..Isoflurane, a halogenated volatile anesthetic, is thought to produce anesthesia by depressing central nervous system function...
- Isoflurane: Identification of Key New TargetsAaron P Fox; Fiscal Year: 2010..Isoflurane, a halogenated volatile anesthetic, is thought to produce anesthesia by depressing central nervous system function...
- Propofol Interactions with GABA-A ReceptorsMYLES AKABAS; Fiscal Year: 2009Each year millions of people undergo general anesthesia so that surgeons can perform life-saving operations...
- Propofol Interactions with GABA-A ReceptorsMYLES AKABAS; Fiscal Year: 2007Each year millions of people undergo general anesthesia so that surgeons can perform life-saving operations...